HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODIES AGAINST CD47
CY1125912T1Undetermined Publication Date: 2026-04-17THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
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Patent Information
- Application Number
- CY20221100778T
- Authority / Receiving Office
- CY · CY
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2010-05-14
- Filing Date
- 2022-12-07
- Publication Date
- 2026-04-17
- Estimated Expiration
- 2042-12-07
Abstract
Humanized or chimeric anti-CD47 monoclonal antibodies are provided. The antibodies bind to and neutralize human CD47, and find use in various therapeutic methods. Non-activating antibodies are preferred. Embodiments of the invention include isolated antibodies and derivatives and fragments thereof, pharmaceutical compositions comprising one or more of the humanized or chimeric anti-CD47 monoclonal antibodies; and cell lines which produce these monoclonal antibodies. Amino acid sequences of the antibodies are also provided.
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