Automatic analysis device, data processing device, data processing method and program

Abstract

A purpose of the present invention is to provide an autonomous analysis device with which an operator can easily associate and confirm a reaction course and an illness. In order to achieve this purpose, the present invention provides an autonomous analysis device comprising an analysis unit for analyzing a sample, an operation unit for accepting an operation from an operator, a control unit for controlling the analysis unit on the basis of an input from the operation unit and computing measurement data using a measurement value acquired from the analysis unit, and a display unit for displaying the measurement data computed by the control unit, wherein the control unit causes the display unit to display not only measurement reaction course information that is based on the measurement data of the sample being analyzed, but also reference reaction course information that is designated by the operation unit from among items of reference reaction course information classified in advance for each illness.

Description

[Technical field]

[0001] The present invention relates to an automatic analyzer. [Background technology]

[0002] One of the tests that can be measured using an automated analyzer is a blood coagulation test. A blood coagulation test measures a patient's blood clotting ability, and the main items are PT (prothrombin time), APTT (activated partial thromboplastin), and Fbg (fibrinogen concentration). The coagulation reaction begins when the patient's sample is mixed with a reagent. The coagulation reaction process is monitored by the amount of change in scattered light or absorbance to detect the coagulation point, and the clotting time is measured. In recent years, there has been progress in clot waveform analysis (CWA), which extracts the entire coagulation reaction process, especially PT and APTT, as a clot waveform and analyzes the clot waveform.

[0003] As one method of clot waveform analysis, Patent Document 1 discloses a technology that calculates the peak width time at a specified height on the clot reaction rate curve data obtained from the clot reaction waveform data, and determines the concentration of a component involved in coagulation or a coagulation abnormality. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2019-86517 A Summary of the Invention [Problem to be solved by the invention]

[0005] CWA includes the clot waveform and parameters that can be calculated from it, such as the clot velocity, which is the first derivative of the clot waveform, the clot acceleration, which is the second derivative, and the maximum clot velocity and maximum clot acceleration, which are the maximum values ​​of these. The number of devices that can output these is increasing, and in the future, CWA is expected to be used to predict diseases, the severity of bleeding, and hemostatic management.

[0006] However, at present, even if a certain amount of measurement data (measurement results and coagulation reaction process, etc.) is accumulated, it is automatically deleted, or is deleted daily by the operator to avoid the risk of data misinterpretation, and past data is not effectively used for disease prediction. In other words, it is difficult for the operator to determine which disease the coagulation reaction process resembles just by looking at it.

[0007] An object of the present invention is to provide an automatic analyzer that allows an operator to easily link a reaction process with a disease, and a data processing device, data processing method, and program for processing the measurement data obtained thereby. [Means for solving the problem]

[0008] In order to achieve the above-mentioned object, the automatic analyzer of the present invention comprises an analysis unit that analyzes samples, an operation unit that accepts operations from an operator, a control unit that controls the analysis unit based on input from the operation unit and calculates measurement data using measurement values ​​obtained from the analysis unit, and a display unit that displays the measurement data calculated by the control unit, and the control unit displays on the display unit not only measurement reaction process information based on the measurement data of the sample to be analyzed, but also reference reaction process information specified by the operation unit from reference reaction process information pre-classified by disease. Effect of the Invention

[0009] According to the present invention, it becomes easy for an operator to find similarities between the reaction process of the sample to be analyzed and reaction processes classified by disease in the past, and it is possible to provide an automatic analyzer that can easily link and confirm reaction processes with diseases, as well as a data processing device, data processing method, and program for processing the measurement data. [Brief description of the drawings]

[0010] [Figure 1] FIG. 1 is a schematic diagram illustrating a configuration of an automatic analyzer according to an embodiment of the present invention. [Diagram 2]FIG. 2 is a functional block diagram of a control device provided in the automatic analyzer. [Diagram 3] 11 is a flowchart showing an example of confirmation of the coagulation reaction process of a target sample. [Figure 4] FIG. 13 is a diagram showing an example of a list screen of measurement results by an automatic analyzer. [Diagram 5] FIG. 13 is a diagram showing an example of a list screen of the coagulation reaction process of a target sample. [Figure 6a] FIG. 13 is a diagram showing an example of a screen displaying the clotting reaction process of the APTT measurement item of the target sample alongside the clotting reaction process of the APTT measurement item of a previous test classified as congenital hemophilia A. [Figure 6b] FIG. 13 is a diagram showing an example of a screen displaying the clotting reaction process of the APTT measurement item of the target sample alongside the clotting reaction process of the APTT measurement item of a past measurement item classified as APS. [Figure 7a] FIG. 6B is a diagram showing a state in which the overlay button for overlaying a past clotting reaction process on the clotting reaction process of the target sample is selected on the screen of FIG. 6A. [Figure 7b] FIG. 7b shows an example of an overwrite confirmation screen displayed after the screen of FIG. 7a. [Figure 7c] FIG. 7B is a diagram showing an example of a screen displayed after overwriting has been performed after the screen of FIG. 7B. [Figure 7d] FIG. 7C shows an example of a screen displayed when a reaction process display area that displays the overwritten reaction processes is scrolled. [Figure 8a] FIG. 13 is a diagram showing an example of a screen that prompts selection of a classification and input of a comment, which is displayed when saving the coagulation reaction process of a target sample. [Figure 8b] FIG. 13 is a diagram showing another example of a screen for prompting a user to select a category and input a comment, which is displayed when saving the coagulation reaction process of a target sample. [Figure 9] 6b screen when the reaction process list edit button in the past reaction process display area is selected. FIG. [Figure 10a] FIG. 10 is a diagram showing an example of a confirmation screen for deleting a reaction process, which is displayed when a delete button corresponding to one of the past reaction processes is selected on the screen transitioned to from the screen of FIG. 9. [Figure 10b] FIG. 10 is a diagram showing an example of a comment change screen that is displayed when a comment change button corresponding to one of the past reaction processes is selected on the screen transitioned from the screen of FIG. 9. [Figure 10c] FIG. 10 shows an example of a classification change screen that is displayed when a classification change button corresponding to one of the past reaction processes is selected on the screen transitioned from the screen of FIG. 9. [Figure 11] FIG. 13 is a diagram showing an example of an operation screen for editing keys (tabs) to be assigned to each disease classification. [Figure 12] FIG. 13 is another example of a list screen of the coagulation reaction process of a target sample, which also displays a first derivative curve and a second derivative curve. [Figure 13a] FIG. 13 shows an example of a screen in which the clotting reaction process of the APTT measurement item of the target sample is overlaid with the clotting reaction process of the APTT measurement item of a previous test classified as congenital hemophilia A. [Figure 13b] FIG. 13b shows the first derivative curves overlaid by scrolling the reaction process display area of ​​the target sample in FIG. 13a. [Figure 13c] FIG. 13B shows the second derivative curve overlaid by further scrolling the reaction process display area of ​​the target sample. [Figure 14] FIG. 13 is a basic configuration diagram of an analysis system including an automatic analyzer and a data processing device according to another embodiment. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0011] Hereinafter, an embodiment of the present invention will be described with reference to the drawings.

[0012] (Configuration of the automatic analyzer) 1 is a schematic diagram showing the configuration of an automatic analyzer according to an embodiment of the present invention. In this embodiment, an example of an application is an integrated automatic analyzer having functions of biochemical analysis, blood coagulation analysis (blood coagulation fibrinolysis markers, blood coagulation time measurement, etc.), and immune analysis.

[0013] 1 includes an analysis unit 1 (analysis section) that analyzes samples, an operation device 2 (operation section) that accepts operations from an operator, a control device 3 (control section) that controls the analysis unit 1 based on input from the operation device 2 and calculates measurement data using measurement values ​​obtained from the analysis unit 1, and a monitor 4 (display section) that displays and outputs the measurement data calculated by the control device 3. The samples analyzed by the automatic analysis device 100 are specimens such as blood or urine from patients.

[0014] <Analysis unit> The analysis unit 1 is composed of a reaction disk 10, a sample disk 20, a first reagent disk 30A, a second reagent disk 30B, a sample dispensing mechanism 40, a first reagent dispensing mechanism 50A, a second reagent dispensing mechanism 50B, a first measurement unit 60A to a third measurement unit 60C, and a first reading device 70A to a third reading device 70C.

[0015] -Reaction Disc- The reaction disk 10 is a disk-shaped unit that can rotate around a vertical axis, and holds a large number of reaction containers (reaction cells) 11 made of a light-transmitting material. The reaction containers 11 are containers for mixing and reacting a sample with a reagent, and a plurality of reaction containers 11 are arranged in a ring shape on the reaction disk 10. When the automatic analyzer 100 is in operation, the reaction containers 11 are kept at a predetermined temperature (for example, about 37°C) in a thermostatic bath 12 of the reaction disk 10. The reaction disk 10 is also equipped with a stirring mechanism 13 and a reaction container washing mechanism 14. The stirring mechanism 13 is a device that stirs the liquid contained in the reaction container 11. The reaction container washing mechanism 14 is a device that washes the inside of the reaction container 11 after use.

[0016] -Sample disc- The sample disk 20 is a disk-shaped unit that can rotate around a vertical axis, and holds a large number of sample containers 21 that contain samples. Fig. 1 illustrates a configuration in which the sample containers 21 can be arranged on the sample disk 20 in two concentric rows.

[0017] -Reagent disk- The first reagent disk 30A is a disk-shaped unit that can rotate around a vertical axis and holds a number of first reagent bottles 31A. The first reagent bottles 31A are arranged in a ring shape on the first reagent disk 30A. Similarly, the second reagent disk 30B is a disk-shaped unit that can rotate around a vertical axis and holds a number of second reagent bottles 31B. The second reagent bottles 31B are arranged in a ring shape on the second reagent disk 30B. The first reagent bottles 31A and the second reagent bottles 31B contain reagent liquids corresponding to the analysis items analyzed by the automatic analyzer 100. Each of the first reagent bottles 31A on the first reagent disk 30A contains a first reagent or a coagulation reagent used for, for example, biochemistry or scattering, and each of the second reagent bottles 31B on the second reagent disk 30B contains a second reagent used for, for example, biochemistry or scattering.

[0018] -Sample dispensing mechanism- The sample dispensing mechanism 40 has a pipette nozzle and aspirates and discharges a sample using the pipette nozzle. The sample dispensing mechanism 40 is located between the sample disk 20 and the reaction disk 10. The sample dispensing mechanism 40 aspirates a predetermined amount of sample from inside the sample container 21 located at the dispensing position (aspirating position) 20a of the sample disk 20, and discharges the aspirated sample into the inside of the reaction container 11 located at the dispensing position (discharging position) 10a of the reaction disk 10.

[0019] -Reagent dispensing mechanism- The first reagent dispensing mechanism 50A and the second reagent dispensing mechanism 50B each have a pipette nozzle, and aspirate and discharge a reagent using the pipette nozzle. The first reagent dispensing mechanism 50A is located between the first reagent disk 30A and the reaction disk 10. The second reagent dispensing mechanism 50B is located between the second reagent disk 30B and the reaction disk 10. The first reagent dispensing mechanism 50A aspirates a reagent from inside a first reagent bottle 31A corresponding to a test item at a dispensing position (aspiration position) 30Aa on the first reagent disk 30A, and discharges (dispenses) the reagent into a target reaction container 11 at a dispensing position (discharge position) 10b on the reaction disk 10. Similarly, the second reagent dispensing mechanism 50B aspirates a reagent from inside a second reagent bottle 31B corresponding to the test item at a dispensing position (aspiration position) 30Ba on the second reagent disk 30B, and discharges (dispenses) the reagent into a target reaction vessel 11 at a dispensing position (discharge position) 10c on the reaction disk 10. The reagent discharged into the reaction vessel 11 is stirred by the stirring mechanism 13 and mixed with the sample.

[0020] -Measurement unit- The first to third measurement units 60A to 60C are units for measuring target items of a sample, and each includes a light source that irradiates light onto a mixture of the sample and reagent inside a reaction vessel, and a photometer that detects the light that has passed through the mixture and outputs a measurement value. The first to third measurement units 60A to 60C measure the reaction of the sample and reagent inside the reaction vessel, thereby measuring the target items of the sample.

[0021] The first measurement unit 60A and the second measurement unit 60B are measurement units used for biochemical analysis and immunological analysis. The first measurement unit 60A includes a first light source 61A and a first photometer 62A. The second measurement unit 60B includes a second light source 61B and a second photometer 62B. The first light source 61A and the second light source 61B are arranged on the inner circumference side of the reaction disk 10, and irradiate light to the reaction vessel 11 from the inner circumference side of the reaction disk 10. The first photometer 62A and the second photometer 62B are arranged on the outer circumference side of the reaction disk 10, and face the first light source 61A and the second light source 61B, respectively, across the annular row of the reaction vessel 11. The first photometer 62A and the second photometer 62B are located on the optical axis of the first light source 61A and the second light source 61B, respectively. Light irradiated from a first light source 61A passes through the reaction vessel 11 and is measured by a first photometer 62A. Similarly, light irradiated from a second light source 61B passes through the reaction vessel 11 and is measured by a second photometer 62B. Each time the reaction vessel 11 passes through the first measurement unit 60A and the second measurement unit 60B as the reaction disk 10 rotates, the reaction liquid (mixture of sample and reagent) contained therein is photometered. Used reaction vessels 11 are washed by a reaction vessel washing mechanism 14 and are used repeatedly.

[0022] The third measurement unit 60C is a blood coagulation time measurement unit and includes a reaction vessel storage section 63, a reaction vessel transport mechanism 64, a sample dispensing station 65, a reaction vessel temperature control block 66, a reagent dispensing mechanism 67, and a measurement channel 68.

[0023] In the third measurement unit 60C, a plurality of disposable reaction vessels 60a are accommodated in a reaction vessel accommodation section 63. These reaction vessels 60a are transferred to a sample dispensing station 65 by a reaction vessel transfer mechanism 64. The sample dispensing station 65 is disposed so as to sandwich the sample dispensing mechanism 40 between itself and the sample disk 20. The sample is aspirated from the sample vessel 21 by the sample dispensing mechanism 40 and discharged (dispensed) into the reaction vessel 60a in the sample dispensing station 65.

[0024] The reaction vessel 60a into which the sample has been dispensed in this manner is transferred by the reaction vessel transfer mechanism 64 from the sample dispensing station 65 to the reaction vessel temperature adjustment block 66, where it is heated to approximately 37°C. The reagent is kept cold on the first reagent disk 30A, and the first reagent dispensing mechanism 50A aspirates the reagent from the first reagent bottle 31A corresponding to the test item, and dispenses it into a predetermined empty reaction vessel 11 placed on the reaction disk 10, where it is heated to approximately 37°C.

[0025] After a certain time has elapsed, the reagent kept warm inside the reaction vessel 11 is sucked up by a reagent dispensing mechanism 67 with a reagent heating function, and the temperature is further raised to about 40°C by the reagent dispensing mechanism 67. During this time, the reaction vessel 60a in which the sample is kept warm at about 37°C is transferred to an arbitrary measurement channel 68 of the third measurement unit 60C by the reaction vessel transfer mechanism 64. The third measurement unit 60C is provided with a plurality of measurement channels 68 each having a light source and a photometer. After that, the warmed reagent is discharged (dispensed) into the reaction vessel 60a of the measurement channel 68 by the reagent dispensing mechanism 67, and a blood coagulation reaction between the sample and the reagent starts inside the reaction vessel 60a.

[0026] In the measurement channel 68, after the reagent is dispensed into the reaction vessel 60a, measurement data is output from the photometer at a predetermined time interval (for example, every 0.1 seconds). When the measurement is completed, the used reaction vessel 60a is transferred by the reaction vessel transfer mechanism 64 and disposed of in the reaction vessel disposal unit 69.

[0027] As described above, in the first measurement unit 60A to the third measurement unit 60C, the scattered light is photoelectrically converted by the photometer, and a measurement signal (analog signal) having a magnitude proportional to the scattered light intensity is output from the photometer. These measurement signals are converted into digital signals by the A / D converter 79 and input to the control device 3.

[0028] -Reading device- The first reading device 70A to the third reading device 70C are devices that read the identification data attached to the container. Although barcodes, RFID, etc. can be used as the identification data, an example using barcodes will be described in this example. In other words, the first reading device 70A to the third reading device 70C are barcode readers.

[0029] The first reading device 70A reads the barcode attached to the first reagent bottle 31A when the reagent is registered. The identification data of the reagent read by the first reading device 70A is transmitted to the control device 3 together with the position data of the first reagent bottle 31A on the first reagent disk 30A to which the identification data is attached, and is stored in the memory 6.

[0030] The second reader 70B reads the barcode affixed to the second reagent bottle 31B when the reagent is registered. As with the first reader 70A, the identification data of the reagent read by the second reader 70B is also transmitted to the control device 3 together with the position data of the second reagent bottle 31B on the second reagent disk 30B to which the identification data is attached, and is stored in the memory 6.

[0031] The third reader 70C reads the barcode affixed to the sample container 21 when the sample is registered. The barcode contains data such as the sample ID, patient ID, and sample type. As with the first reader 70A and the second reader 70B, the sample identification data read by the third reader 70C is also transmitted to the control device 3 together with the position data on the sample disk 20 of the sample container 21 to which this identification data is attached, and is stored in the memory 6.

[0032] 1 is equipped with a function for avoiding carryover of samples and reagents, i.e., a function for reducing or avoiding carryover by performing a cleaning operation between measurements. The cleaning operation for avoiding carryover can be performed on the first reagent dispensing mechanism 50A, the second reagent dispensing mechanism 50B, each pipette nozzle of the sample dispensing mechanism 40, and the reaction vessel 11.

[0033] <Operating device> The operation device 2 is a device that an operator or the like operates when inputting measurement request data (described later) into the computer 7 and displaying various data on the monitor 4. As the operation device 2, a keyboard and a mouse can typically be used, but a touch panel or other operation devices can also be applied.

[0034] <Control device> The control device 3 includes an interface 5, a memory 6, a computer 7 (first computer), a control computer 8 (second computer), and a server 9 (third computer).

[0035] -Interface- The interface 5 is an input / output unit for data of the computer 7 to the analysis unit 1. Although the computer 7 and the interface 5 are shown separately in FIG. 1, the interface 5 may be configured integrally with the computer 7. Data on analysis items sent from the computer 7 to the analysis unit 1 is input to the control computer 8 via the interface 5. Furthermore, the measurement data by the first measurement unit 60A to the third measurement unit 60C output from the analysis unit 1 via an A / D converter 79 is input to the computer 7 and memory 6 via the interface 5. The identification data read by the first reading device 70A to the third reading device 70C is also input to the computer 7 and memory 6 via the interface 5.

[0036] -Memory- The memory 6 is a storage device such as an HDD or SSD, and while Fig. 1 illustrates an external storage device connected to the computer 7 via the interface 5, a storage device built into the computer 7 may also be used. The memory 6 stores data such as reagent identification information, sample identification information, analysis parameters, measurement request data, calibration results, and measurement data. The measurement request data includes at least a sample ID and measurement items, and may also include other information such as a patient ID as necessary.

[0037] -computer- The computer 7 is a control device used by an operator, etc. This computer 7 has a function of creating measurement request data in response to the operation of the operator, etc., outputting the data to the control computer 8, and displaying a screen on the monitor 4 in response to the operation of the operator, etc., based on the measurement data from the analysis unit 1, etc.

[0038] 1 illustrates an example of a configuration in which only one analysis unit 1 is connected to the computer 7, but multiple analysis units 1 may be connected to one computer 7 via the interface 5. When connecting multiple analysis units 1 within a facility, a network (such as a LAN) may be connected to the interface 5, and multiple analysis units 1 may be connected to one computer 7 via the network.

[0039] -Control computer- The control computer 8 is a control device that outputs a command signal to the analysis unit 1 according to the measurement request data input from the computer 7, and commands the analysis. It is assumed that the control computer 8 is configured integrally with the analysis unit 1 (built inside the body of the analysis unit 1), but in FIG. 1 it is illustrated separately from the analysis unit 1. The objects to which the control computer 8 issues commands are mechanisms (operating devices) such as the sample disk 20, the first reagent disk 30A, the second reagent disk 30B, the sample dispensing mechanism 40, the first reagent dispensing mechanism 50A, the second reagent dispensing mechanism 50B, the reaction vessel transport mechanism 64, and the reagent dispensing mechanism 67. This embodiment is an example in which one control computer 8 drives the analysis unit 1 in an integrated manner, but it is also possible to configure the system so that each operating device is provided with a dedicated control computer, and each control computer drives the corresponding operating device in response to an input from the computer 7.

[0040] -server- The server 9 is connected to the computer 7. Although Fig. 1 shows a configuration in which the computer 7 and the server 9 are connected without the interface 5, the server 9 may be connected to the computer 7 via the interface 5. In addition, the computer 7 and the server 9 may be connected via a network.

[0041] <Monitor> The monitor 4 is connected to the computer 7, and is a display device that displays and outputs a graphical user interface and various data when operating the computer 7. The various data that the monitor 4 displays and outputs include measurement data by the analysis unit 1, judgment results by the computer 7, patient data, etc., and desired data is displayed on the monitor 4 by a signal input from the computer 7 in response to the operation of the operation device 2 by an operator, etc.

[0042] (Basic operations - biochemical testing) A description will be given of an example of a basic operation using the automatic analyzer 100. Here, the analysis operation will be described for measurement items related to blood coagulation and fibrinolysis markers such as D-dimer and FDP in biochemical tests and blood coagulation tests of a sample using the first photometer 62A.

[0043] Operation parameters for measurement items that can be analyzed by the automatic analyzer 100 are input in advance to the computer 7 by an operator or the like and stored in the memory 6. Measurement request data for each sample is input by an operator or the like. When it is the turn to measure a certain sample ID for which measurement request data has been input, operation parameters corresponding to the measurement items of the corresponding measurement request data are read from the memory 6 and input from the computer 7 to the control computer 8. The control computer 8 then drives the analysis unit 1 in accordance with the operation parameters.

[0044] Specifically, the reaction disk 10 and the sample disk 20 are driven by an operation command from the control computer 8, and the target reaction vessel 11 and the sample vessel 21 are moved to the dispensing positions 10a and 20a, respectively. Then, the sample dispensing mechanism 40 aspirates a predetermined amount of sample from the target sample vessel 21 at the dispensing position 20a, and dispenses it into the target reaction vessel 11 at the dispensing position 10a on the reaction disk 10. The reaction vessel 11 into which the sample has been dispensed is moved from the dispensing position 10a to the dispensing position 10b or 10c by the rotating reaction disk 10, and the first reagent dispensing mechanism 50A or the second reagent dispensing mechanism 50B dispenses a reagent according to the measurement item. The order of dispensing the sample and the reagent may be reversed (the reagent is dispensed before the sample).

[0045] Thereafter, when the reaction vessel 11 passes the first measurement unit 60A, the light transmitted through the sample is measured by the first photometer 62A, and the measurement value by the first photometer 62A is converted to a digital signal by the A / D converter 79 and input to the computer 7 via the interface 5. In the computer 7, the concentration of the mixture of the sample and the reagent is calculated as measurement data based on the calibration curve data corresponding to the measurement item and the measurement value. The calibration curve data is measured in advance using a specified analysis method and stored in the memory 6. The measurement data calculated by the computer 7 is displayed and output on the monitor 4 in response to the operation of an operator or automatically.

[0046] The measurement data can be calculated by a control computer 8 instead of the computer 7. The analysis unit 1 in Fig. 1 uses a turntable type reaction disk 10, which allows samples to be dispensed continuously by the rotation of the disk, and has the characteristic of excellent processing capacity.

[0047] (Basic operation - blood coagulation test) Another example of the basic operation using the automatic analyzer 100 will be described. Here, the analytical operation relating to the measurement of a hemostatic function test item, that is, the measurement of blood coagulation time, will be described. In the measurement of blood coagulation time as well, the analytical unit 1 is driven by the control computer 8 in accordance with the operating parameters.

[0048] Specifically, the reaction vessel 60a accommodated in the reaction vessel accommodation section 63 in the third measurement unit 60C is transferred to the sample dispensing station 65 by the reaction vessel transfer mechanism 64. Then, the sample aspirated from the corresponding sample vessel 21 of the sample disk 20 is dispensed into the reaction vessel 60a in the sample dispensing station 65 by the sample dispensing mechanism 40. The reaction vessel 60a into which the sample has been dispensed is transported by the reaction vessel transfer mechanism 64 to the reaction vessel temperature adjustment block 66, where it is heated to 37°C.

[0049] On the other hand, the first reagent dispensing mechanism 50A aspirates a reagent from a first reagent bottle 31A corresponding to the measurement item and dispenses it into a predetermined empty reaction container 11 installed on the reaction disk 10. The reagent kept cold on the first reagent disk 30A is heated to about 37° C. on the reaction disk 10.

[0050] After a certain time has passed, the reagent kept warm in the reaction vessel 11 is sucked up by a reagent dispensing mechanism 67 with a reagent heating function, and the temperature is further raised, for example, to 40° C. inside the reagent dispensing mechanism 67. During this time, the reaction vessel 60a containing the sample is transferred from the reaction vessel temperature control block 66 to a predetermined measurement channel 68 by the reaction vessel transfer mechanism 64. The heated reagent is then dispensed into the reaction vessel 60a in the measurement channel 68 by the reagent dispensing mechanism 67. This reagent dispensing initiates a blood coagulation reaction between the sample and the reagent inside the reaction vessel 60a.

[0051] After the reagent is thus discharged, the light measurement values ​​are sequentially output at predetermined short measurement time intervals (for example, every 0.1 seconds) in the measurement channel 68. The output measurement values ​​are converted into digital signals by the A / D converter 79 and input to the computer 7 via the interface 5. After the photometry is completed, the used reaction vessel 60a is transported by the reaction vessel transport mechanism 64 and disposed of in the reaction vessel disposal section 69.

[0052] The computer 7 thus determines the blood clotting time from the measured value input from the analysis unit 1. Thereafter, the concentration of the mixture of the sample and the reagent is calculated as measurement data based on the calibration curve data corresponding to the measurement item and the calculated blood clotting time. The measurement data and blood clotting time calculated by the computer 7 are displayed on the monitor 4 either automatically or in response to the operation of an operator.

[0053] In the third measurement unit 60C, since the measurement values ​​must be collected for a certain period of time, only one reaction vessel 60a can be measured per measurement channel 68 during that period. Although a configuration having six measurement channels 68 is illustrated in FIG. 1, when there are no free measurement channels 68, the next blood coagulation time measurement cannot be accepted and the system goes into a standby state. From the viewpoint of preventing such a standby state from occurring, a configuration having many measurement channels 68 is advantageous.

[0054] (Control device functions) Fig. 2 is a functional block diagram of a control device provided in the automatic analyzer. In Fig. 2, elements corresponding to those in Fig. 1 are given the same reference numerals as in Fig. 1, and descriptions thereof will be omitted as appropriate. As shown in Fig. 2, the control device 3 has the functions of measurement order management F1, mechanism control F2, data calculation F3, and data management F4.

[0055] These functions are realized by executing the programs by the processor of the computer, in cooperation with other hardware to perform the specified processes. The programs for realizing these functions are stored in the memory 6. The programs may be provided by being incorporated in the memory 6 in advance, or may be provided by being recorded in a computer-readable recording medium such as a CD-ROM in the form of an installable or executable file. Furthermore, the programs can also be downloaded from a computer connected via a network and installed in the memory 6.

[0056] In the present embodiment, the following description assumes that these functions are shared and executed by multiple computers, specifically, that the functions of measurement order management F1 and mechanism control F2 are executed by a control computer 8, and the other two functions are executed by a computer 7. However, a configuration in which all functions are executed by a single computer may also be used.

[0057] -Measurement order management- Measurement order management F1 is a function for setting the measurement order of samples. This function of measurement order management F1 is assumed to be executed by the control computer 8, but may be executed by the computer 7. Measurement request data set by the operation device 2 in the computer 7 is input from the computer 7 to the control computer 8. For ease of explanation, specific measurement request data will be referred to as measurement request data X, and a sample whose ID is specified in the measurement request data X will be referred to as sample Y. When the measurement request data X is input from the computer 7, the control computer 8 sets the measurement order for sample Y, such as which sample to measure next.

[0058] -Mechanism control- The mechanism control F2 is a function that controls the operation of the analysis unit 1. The function of this mechanism control F2 is executed by the control computer 8. When the measurement order of sample Y set in the measurement order management F1 arrives, the control computer 8 drives the analysis unit 1 to perform measurement on sample Y. Specifically, the sample Y placed on the sample disk 20 is dispensed into the reaction vessel 11 or 60a according to the measurement item specified in the measurement request data X, and is mixed with a reagent according to the measurement item as described above to cause a reaction.

[0059] -Data Calculation- Data calculation F3 is a function that calculates measurement data from the measurement values ​​input from the analysis unit 1. This function of data calculation F3 is executed by, for example, the computer 7. When the sample Y is reacted with a reagent by the mechanism control F2, photometric values ​​for the sample Y are input from the first measurement unit 60A to the third measurement unit 60C via the A / D converter 79. Measurement data for the measurement items specified for the sample Y is calculated based on these measurement values. The measurement data for the sample Y calculated here is stored in the memory 6 together with the measurement values, reagent identification information, sample identification information, analysis parameters, measurement request data, calibration results, etc.

[0060] -Data Management- Data management F4 is a function for managing measurement data. This function of data management F4 is executed by, for example, computer 7. Specifically, computer 7 links data (measurement data, etc.) on sample Y calculated in data calculation F3 with the sample ID of sample Y. At the same time, the measurement data, etc. on sample Y stored in memory 6 is also linked with the sample ID of sample Y. Then, computer 7 displays and outputs the measurement data, etc. of sample Y processed in data management F4 on monitor 4 automatically or in response to an operation by an operator, etc. In addition, the measurement data, etc. linked with the sample ID of sample Y is transmitted from computer 7 to server 9 and accumulated in the memory (storage unit) of server 9. In this way, the memory of server 9 is an examination information database that stores past measurement data. In addition, the memory of server 9 stores electronic medical records for each patient ID in addition to the measurement data for each patient ID, and also serves as a patient information database that collects various data on individual patients. The electronic medical record records the doctor's findings during the examination, the patient's symptoms, medical history, medication history, family history, etc.

[0061] (Example of confirming the clotting reaction process of a target sample) FIG. 3 is a flow chart showing an example of confirmation of the coagulation reaction process of a target sample.

[0062] First, for a blood coagulation test specified in the measurement request data, when the measurement data for the target patient ID is output by computer 7 through the process of mechanism control F2, the reaction process confirmation process shown in Fig. 3 is started. Then, computer 7 calculates the measurement data of the blood coagulation test (step S101), stores the measurement data file of the measurement data of the blood coagulation test in memory 6 (step S102), and displays the measurement results on monitor 4 (step S103).

[0063] At this time, by performing a predetermined operation on the screen of the monitor 4, the coagulation reaction process can be confirmed (step S104). When the predetermined operation is performed in step S104, the computer 7 causes the monitor 4 to display the coagulation reaction process of the target sample (step S105). At this time, the screen of the monitor 4 also displays a button for referring to past coagulation reaction processes stored in the memory of the automatic analyzer 100 or the database of the server 9 (hereinafter, database, etc.), and a button for saving the coagulation reaction process of the target sample in the database, etc.

[0064] Here, when a button for referring to the past coagulation reaction process is selected (step S106), the computer 7 causes the monitor 4 to display a list of the past coagulation reaction processes (step S107).

[0065] The past coagulation reaction processes are classified in advance by disease and stored in a database or the like. When a predetermined coagulation reaction process classified into a predetermined disease is designated (step S108) and the overwrite button is operated (step S109), the computer 7 overwrites the designated past coagulation reaction process graph on the coagulation reaction process graph of the target sample (step S110). In this way, not only the measurement reaction process information based on the measurement data of the sample to be analyzed, but also the designated reference reaction process information from the past reference reaction process information classified in advance by disease is displayed, so that the operator can easily find similar reaction processes and easily match disease patterns.

[0066] On the other hand, after step S105, when a button for saving the clotting reaction process of the target sample is selected (step S111), the computer 7 displays on the monitor 4 a screen prompting the user to select a classification (by disease) of the clotting reaction process to be saved and to input a comment (step S112). Then, when the selection of the classification and the input of a comment (optional) are completed and a confirmation operation for saving is performed, the computer 7 saves the clotting reaction process of the target sample in a database or the like (step S113).

[0067] (Example of screen display) Fig. 4 is a diagram showing an example of a list screen of the measurement results obtained by the automatic analyzer. Each screen described hereinafter in this specification, including the screen in Fig. 4, is displayed and output on the monitor 4 by the computer 7 in response to an operation by an operator or the like. Furthermore, operations including the selection of tabs on the screen are performed by the operator or the like using the operation device 2.

[0068] The screen in FIG. 4 is displayed when a tab 401 labeled "measurement results" is selected (clicked) on a specific screen displayed on the monitor 4. The screen in FIG. 4 has a measurement status display area 400a for each sample, an item-specific result display area 400b that displays the results for each measurement item of the selected sample, and a button display area 400c for each function. The result column for each sample in the measurement status display area 400a is provided with a reaction process details button 402 for viewing the reaction process of the analysis target. In this embodiment, not only blood coagulation tests but also biochemical and immunological test reaction processes can be saved and referenced. The button display area 400c for each function has a reaction process reference button 403 that allows past reaction processes to be referenced.

[0069] Fig. 5 is a diagram showing an example of a list screen of the coagulation reaction process of a target sample. The screen of Fig. 5 is displayed when the reaction process detail button 402 corresponding to the topmost sample is selected on the screen of Fig. 4, and a list of the reaction processes of the selected sample is displayed in a reaction process list display area 501. A reaction process reference button 502 and a reaction process save button 503 are displayed to the right of each reaction process. In the example of Fig. 5, the reaction process reference button 502 is selected to refer to and compare past reaction processes for the measurement item of APTT among the selected samples.

[0070] FIG. 6a is a diagram showing an example of a screen displaying the coagulation reaction process of the measurement item APTT of the target sample and the coagulation reaction process of the past measurement item APTT classified as congenital hemophilia A side by side. The screen of FIG. 6a is displayed when the reaction process reference button 502 corresponding to the measurement item APTT is selected on the screen of FIG. 5 and then executed. On the screen of FIG. 6, a past reaction process display area 602 is displayed vertically side by side with a reaction process display area 601 of the target sample. The past APTT reaction processes are stored in a database or the like for each disease, and when tabs 604 to 607 are selected (clicked) in the past reaction process display area 602, the past APTT reaction processes stored for each disease are displayed. Note that the display names of the tabs can be changed or added by an operator or the like, as described later. In addition, a reaction process list edit button 608 and a reaction process overwrite button 609 are also displayed in the past reaction process display area 602. In the example of FIG. 6a, since the tab 604 has been selected (clicked), a list of past reaction processes saved as congenital hemophilia A is displayed in the past reaction process display area 602.

[0071] In addition, when the reaction process reference button 403, which allows reference to past reaction processes, is selected (clicked) on the screen of Figure 4, a screen is displayed in which the reaction process of the selected measurement item is selected for confirmation, and then the reaction process of the selected measurement item is displayed.

[0072] Fig. 6b is a diagram showing an example of a screen displaying the coagulation reaction process of the measurement item APTT of the target sample alongside the coagulation reaction process of the past measurement item APTT classified as APS. The screen of Fig. 6b is displayed when tab 606 is selected (clicked) on the screen of Fig. 6a. On the screen of Fig. 6b, the coagulation reaction process of the past measurement item APTT classified as APS is displayed in the past reaction process display area 602. In addition, comments can be entered for all reaction processes stored in a database or the like, and the entered comments are displayed in a comment display field 610.

[0073] Fig. 7a is a diagram showing a state in which an overwrite button for overlaying and displaying a past coagulation reaction process on the coagulation reaction process of a target sample is selected on the screen of Fig. 6a. As shown in Fig. 7a, in a past reaction process display area 702, a tab 704, i.e., congenital hemophilia A, is selected (clicked), so that a list of past reaction processes saved as congenital hemophilia A is displayed, and in this state, a reaction process overwrite button 709 is selected (clicked).

[0074] Fig. 7b is a diagram showing an example of an overwrite confirmation screen displayed after the screen of Fig. 7a. When the reaction process overwrite button 709 is selected (clicked) in Fig. 7a, an overwrite confirmation box 710 is displayed as shown in Fig. 7b, along with an overwrite execute button 711 and an overwrite cancel button 712. In the example of Fig. 7b, the overwrite execute button 711 has been selected (clicked).

[0075] Fig. 7c is a diagram showing an example of a screen after overwriting, which is displayed after the screen of Fig. 7b. When the overwriting execution button 711 is selected (clicked) on the screen of Fig. 7b, as shown in Fig. 7c, the clotting reaction process 713 (solid line) of the measurement item APTT of the target sample and the clotting reaction process 714 (dotted line) of the past measurement item APTT classified as congenital hemophilia A are displayed in an overlaid manner in the reaction process display area 701 of the target sample. Since they are displayed in an overlaid manner in this way, it is easier to compare them with the reaction process pattern corresponding to the disease.

[0076] FIG. 7d is a diagram showing an example of a screen when the reaction process display area displaying the overwritten reaction process on the screen of FIG. 7c is scrolled. The reaction process display area 701 of the target sample displays a graph legend 715, date 716, sample ID 717, measurement item name 718, measurement value 719, unit 720, and classification 721. As shown in FIG. 7d, scrolling the reaction process display area 701 displays the measurement results and classification 721 of the past reaction process that are overwritten. Note that multiple reaction processes can be overwritten, and the line style changes to make the reaction process easier to see, and the style is displayed in the graph legend 715.

[0077] FIG. 8a is a diagram showing an example of a screen that prompts the user to select a classification and input a comment when saving the coagulation reaction process of the target sample. The screen of FIG. 8a is displayed after the reaction process save button corresponding to the measurement item APTT is selected on the screen of FIG. 5. In the disease classification selection box 804, the user can select (click) the disease classification to be saved, and in the comment input box 805, the user can input a comment as necessary. When the save execution button 807 is selected (clicked) out of the save cancellation button 806 and the save execution button 807, the reaction process of the target sample is saved in a database or the like. When the disease classification of the target sample is already known, the reaction process of the target sample is classified in this way, and the classification results are saved in a database or the like, thereby expanding the data that can be referred to later as a past reaction process.

[0078] FIG. 8b is a diagram showing another example of a screen that prompts a user to select a classification and input a comment when saving the coagulation reaction process of a target sample. The screen of FIG. 8b is displayed after the Save Reaction Process button in the target sample reaction process display area 701 is selected on the screen of FIG. 7a. As in the case of FIG. 8a, the disease classification selection box 804 allows the user to select (click) a disease classification to be saved, and the comment input box 805 allows the user to input a comment as necessary. In addition, when the Save Execute button 807 is selected (clicked) out of the Cancel Save button 806 and the Save Execute button 807, the reaction process of the target sample is saved in a database or the like. In this way, the reaction process of the target sample can be classified while referring to past reaction processes, and the classification results can be saved in a database or the like.

[0079] Fig. 9 is a diagram showing a state in which the Edit Reaction Process List button in the past reaction process display area is selected on the screen of Fig. 6b. As shown in Fig. 9, in the past reaction process display area 902, a tab 905, i.e., APS, is selected (clicked), so a list of past reaction processes saved as APS is displayed, and in this state, the Edit Reaction Process List button 907 is selected (clicked).

[0080] FIG. 10a is a diagram showing an example of a confirmation screen for deleting a reaction process, which is displayed when a delete button corresponding to one of the past reaction processes is selected on a screen transitioned from the screen of FIG. 9. In FIG. 9, when the APS tab is selected and the edit reaction process list button in the past reaction process display area is selected (clicked), a delete reaction process button 1007, a change comment button 1008, a change disease classification button 1009, and a comment display field 1012 (if a comment is entered) are displayed for each of the past reaction processes saved as an APS. Note that in FIG. 10a, only the past reaction process area 1001 and the previous past reaction process area 1002 are displayed, but it is possible to check even more past reaction process areas by scrolling the screen. In addition, the example of FIG. 10a shows a state in which a confirmation box for deleting a reaction process is displayed by selecting (clicking) the delete reaction process button 1007 in the past reaction process area 1001. Furthermore, in the example of FIG. 10a, the delete execution button 1010 is selected (clicked), so that the target reaction process is deleted.

[0081] FIG. 10b is a diagram showing an example of a comment change screen that is displayed when a comment change button corresponding to one of the past reaction processes is selected on the screen transitioned from the screen in FIG. 9. In FIG. 9, when the APS tab is selected and the reaction process list edit button in the past reaction process display area is selected (clicked), multiple buttons for editing are displayed for each reaction process, as described above. The example in FIG. 10b shows a state in which a comment change box is displayed by selecting (clicking) the comment change button 1008 in the past reaction process area 1001. Here, when a comment is entered in the comment change field 1013 and the comment change completion button 1015 is selected (clicked), the comment change is reflected.

[0082] FIG. 10c is a diagram showing an example of a classification change screen that is displayed when a classification change button corresponding to one of the past reaction processes is selected on a screen transitioned from the screen of FIG. 9. In FIG. 9, when the APS tab is selected and the reaction process list edit button in the past reaction process display area is selected (clicked), multiple buttons for editing are displayed for each reaction process, as described above. The example of FIG. 10c shows a state in which a disease classification change box is displayed by selecting (clicking) the disease classification change button 1009 in the past reaction process area 1001. Here, when the disease classification to be changed is selected (clicked) and the disease classification change completion button 1018 is selected (clicked), the disease classification change is reflected.

[0083] 11 is a diagram showing an example of an operation screen when editing keys (tabs) to be assigned to each disease classification. A disease classification selection area 1101a, a set button 1102, a release button 1103, and a placement selection area 1101b are displayed in a reaction process classification setting area 1101. In the disease classification selection area 1101a, a list of disease classifications 1105 registered in advance is displayed together with comments 1106 entered at the time of registration.

[0084] When allocating a disease classification to a key, an operator or the like selects a desired disease classification in the disease classification selection area 1101a, selects one of the keys (e.g., key 1 to key 10) to which the selected disease classification is to be allocated in the arrangement selection area 1101b, and operates (clicks) the set button 1102. As a result, the disease classification selected in the disease classification selection area 1101a is input to the disease classification 1107 in the arrangement selection area 1101b, and the selected disease classification is allocated to the corresponding key in the check box 1104. FIG. 11 shows a state in which congenital hemophilia B is selected in the disease classification selection area 1101a and key 5 is selected in the arrangement selection area 1101b, and the set button 1102 is operated (clicked), so that congenital hemophilia B is added as the disease classification corresponding to key 5. In addition, the setting of a key to which a disease classification has already been allocated can be cleared by selecting the key in the arrangement selection area 1101b and operating (clicking) the release button 1103. In addition, a comment can be freely input in the comment area 1106.

[0085] FIG. 12 is another example of a list screen of the coagulation reaction process of the target sample, which also displays the first differential curve and the second differential curve. In the example of FIG. 5 described above, only the coagulation reaction process is displayed as the measurement result, but in the example of FIG. 12, not only the coagulation reaction process but also its first differential curve and second differential curve are displayed as the measurement result. For example, for the measurement item PT, the coagulation reaction process 1204 is shown by a solid line, the first differential curve 1205 of the coagulation reaction process is shown by a dashed line, and the second differential curve 1206 of the coagulation reaction process is shown by a dotted line. Similarly, for the measurement item APTT, the coagulation reaction process 1207 is shown by a solid line, the first differential curve 1208 of the coagulation reaction process is shown by a dashed line, and the second differential curve 1209 of the coagulation reaction process is shown by a dotted line. In this way, by displaying not only the reaction process but also its differential curve, it is possible to accurately determine the tendency of the target sample.

[0086] FIG. 13a is a diagram showing an example of a screen when the coagulation reaction process of the APTT measurement item of the target sample, classified as congenital hemophilia A, of the past measurement item is overwritten. In the past reaction process display area 1302, a list of data classified as congenital hemophilia A can be displayed by scrolling, and not only the coagulation reaction process 1310 (solid line) but also its first differential curve 1311 (dashed line) and second differential curve 1312 (dotted line) are displayed for each data. In the example of FIG. 13a, since the reaction process overwrite button 1314 corresponding to a specific data is selected (clicked) in the past reaction process display area 1302, the coagulation reaction process 1303 (solid line) of the measurement item APTT of the target sample and the coagulation reaction process 1310 (dashed line) of the selected past measurement item APTT are overwritten and displayed in the reaction process display area 1301 of the target sample.

[0087] Fig. 13b is a diagram showing first-order differential curves superimposed by scrolling the reaction process display area of ​​the target sample in Fig. 13a. As shown in Fig. 13b, a first-order differential curve 1304 (solid line) of the coagulation reaction process of the measurement item APTT of the target sample and a first-order differential curve 1311 (dashed line) of the coagulation reaction process of a selected past measurement item APTT are superimposed and displayed in the reaction process display area 1301 of the target sample.

[0088] Fig. 13c is a diagram showing the second derivative curves superimposed by further scrolling the reaction process display area of ​​the target sample in Fig. 13b. As shown in Fig. 13c, the reaction process display area 1301 of the target sample displays a second derivative curve 1305 (solid line) of the coagulation reaction process of the measurement item APTT of the target sample and a second derivative curve 1312 (dashed line) of the coagulation reaction process of the selected past measurement item APTT, superimposed on each other.

[0089] In this way, by overwriting the past coagulation reaction process (reference reaction process information) on the coagulation reaction process of the target sample (measurement reaction process information) for comparison, if the disease of the patient sample is unknown, it is possible to predict the disease to some extent from the coagulation reaction process, and if the disease of the patient sample is known, it is possible to reconfirm that the disease is known from the coagulation reaction process. Furthermore, if a disease classification is selected by an operator or the like for the measurement reaction process information, the measurement reaction process information is linked to the selected disease and stored in a database or the like as reference reaction process information, so that repeating such classification selection expands the database, leading to improved accuracy in disease prediction.

[0090] (Other embodiments) The above-mentioned functions (mainly the function of displaying the measurement reaction process information and the reference reaction process information) may be installed in the data processing device 200 that processes the measurement data of the automatic analyzer 100, instead of the main body of the automatic analyzer 100 that analyzes the sample. FIG. 14 is a basic configuration diagram of an analysis system including an automatic analyzer and a data processing device. As shown in FIG. 14, the automatic analyzer 100 and the data processing device 200 are connected via a network 300. That is, the measurement data including the measurement reaction process information measured by the automatic analyzer 100 is transmitted to the data processing device 200, and the past data including the reference reaction process information stored in the data processing device 200 is transmitted to the automatic analyzer 100. This makes it possible to display and operate the above-mentioned on the screen even in the data processing device 200 located away from the automatic analyzer 100. Note that the transmission and reception of data between the automatic analyzer 100 and the data processing device 200 may be performed directly by a wired or wireless communication line without going through the network 300, or may be performed using an external medium.

[0091] The data processing device 200 includes a data acquiring unit 201 that acquires measurement data from the automatic analyzer 100, a memory unit 202 that stores reference reaction process information pre-classified by disease, and an output unit 203 that outputs measurement reaction process information corresponding to the measurement data and reference reaction process information corresponding to a selected disease. The data processing device 200 may be connected to a plurality of automatic analyzers 100.

[0092] The present invention is not limited to the above-described embodiments, but includes various modified examples. For example, the above-described embodiments have been described in detail to clearly explain the present invention, and are not necessarily limited to those having all of the configurations described. In addition, it is possible to replace a part of the configuration of one embodiment with the configuration of another embodiment, and it is also possible to add the configuration of another embodiment to the configuration of one embodiment. In addition, it is possible to add, delete, or replace a part of the configuration of each embodiment with another configuration. [Explanation of symbols]

[0093] 1...analysis unit, 2...operation device, 3...control device, 4...monitor, 6...memory, 7...computer, 8...control computer, 9...server, 10...reaction disk, 11...reaction vessel, 12...thermostatic bath, 13...mixing mechanism, 14...reaction vessel cleaning mechanism, 20...sample disk, 21...sample vessel, 30A...first reagent disk, 30B...second reagent disk, 31A...first reagent bottle, 31B...second reagent bottle, 40...sample dispensing mechanism, 50A...first reagent dispensing mechanism, 50B...second reagent dispensing mechanism, 60A...first measurement unit, 60B...second measurement unit, 60C...third measurement unit, 60a...reaction vessel, 61A...first light source, 61B...second light source, 62A...first photometer, 62B...second photometer, 63...reaction vessel storage section, 64...reaction vessel transfer mechanism, 65...sample dispensing station, 66...reaction vessel temperature control block, 67...reagent dispensing mechanism, 68...measurement channel, 69...reaction vessel disposal section, 70A...first reader, 70B...second reader, 70C...third reader, 79...A / D converter, 100...automatic analyzer, 200...data processing device, 201...data acquisition unit, 202...storage unit, 203...output unit, 300...network, 403, 502, 802, 1202...reaction process reference button, 501, 801, 1201...reaction process list display area, 503, 603, 703, 803, 1203, 1313...reaction process save button, 601, 701, 901, 1301...reaction process display area for target sample, 602, 702, 902, 1302...past reaction process display area, 604, 704, 903 ,1003,1306...Congenital hemophilia A tab,605,705,904,1004,1307...VWF deficiency tab,606,706,905,1005,1308...APS tab,607,707,906,1006,1309...Acquired hemophilia A tab,608,708,907,1317...Reaction process list edit button,609,709,1314...Reaction process overwrite button,610,1012...Comment display,713,1207,1303...Clotting reaction process of the measurement item APTT of the target sample,714,1310...clotting reaction process of past measurement item APTT, 715...legend, 716...date, 717...sample ID, 718...item name, 719...measurement value, 720...unit, 721...classification, 1204...clotting reaction process of measurement item PT of target sample, 1205...first derivative curve of clotting reaction process of measurement item PT of target sample, 1206...second derivative curve of clotting reaction process of measurement item PT of target sample, 1208...first derivative curve of clotting reaction process of measurement item APTT of target sample, 1209...second derivative curve of clotting reaction process of measurement item APTT of target sample, 1304...first derivative curve of clotting reaction process of measurement item APTT of target sample, 1305...second derivative curve of clotting reaction process of measurement item APTT of target sample,

Claims

1. an analysis unit for analyzing the sample; an operation unit that receives operations from an operator; Controlling the analysis unit based on an input from the operation unit, and calculating the measurement value obtained from the analysis unit. A control unit that calculates the measurement data using the A display unit that displays the measurement data calculated by the control unit; In an automatic analyzer comprising: The control unit not only provides measurement reaction process information based on the measurement data of the sample to be analyzed, A reference reaction process information, which is past reaction process information assigned to a specific disease, is displayed on the display unit, The automatic analyzer according to claim 1, wherein the reference reaction process information is selected by the operation unit from a plurality of past reaction process information for each disease.

2. 2. The automated analyzer according to claim 1, The control unit receives the measurement reaction process information, the reference reaction process information, and The automatic analyzer is characterized in that the above-mentioned are displayed side by side or overlapping on the display unit.

3. 2. The automated analyzer according to claim 1, An automatic analyzer characterized in that, when a disease classification is selected by the operation unit for the measurement reaction process information, the measurement reaction process information is linked to the selected disease and stored as the reference reaction process information.

4. 2. The automated analyzer according to claim 1, The automatic analyzer is characterized in that the control unit is connected to a server that stores the reference reaction process information.

5. A data processing device that processes measurement data from an automatic analyzer that analyzes a sample, A data acquisition unit that acquires measurement data from an automatic analyzer; A storage unit that stores reference reaction process information that is pre-classified by disease; and an output unit that outputs measurement reaction process information corresponding to the measurement data and reference reaction process information designated from a plurality of pieces of past reaction process information assigned to each disease.

6. A data processing method for processing measurement data of an automatic analyzer that analyzes a sample, comprising the steps of: Measurement reaction process information based on measurement data of the sample to be analyzed; Reference reaction process information designated from among a plurality of past reaction process information assigned to each disease; A data processing method that outputs:

7. A program to be executed by a computer included in an automatic analyzer or a computer connected to the automatic analyzer, Measurement reaction process information based on measurement data of the sample to be analyzed; Reference reaction process information designated from among a plurality of past reaction process information assigned to each disease; A program that executes the process of outputting.

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