Method for preparing trioxane derivatives
The method enhances trioxane derivative synthesis by using esters, compounds, and controlled reaction conditions to achieve a high yield and selectivity, addressing the inefficiencies of previous methods.
JP7877519B2Active Publication Date: 2026-06-22EVONIK OXENO GMBH & CO KG
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- EVONIK OXENO GMBH & CO KG
- Filing Date
- 2025-01-31
- Publication Date
- 2026-06-22
AI Technical Summary
Technical Problem
Existing methods for preparing trioxane derivatives suffer from low yield and efficiency, as exemplified by the 40% formaldehyde conversion rate in U.S. Patent Application Publication No. 2017/0233366.
Method used
A method involving the introduction of an ester of formula (I), addition of a compound of formula (II), PtI2, CO, and H2, followed by heating, to convert the ester to a trioxane derivative, with specific conditions such as solvent use and pressure control, allowing for higher yield and selectivity.
Benefits of technology
The method achieves a high yield of 98% with a selectivity of 98.2:1.8, producing a trioxane derivative with high purity and stability.
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Abstract
To provide a method for preparing trioxane derivatives that achieves a good yield.SOLUTION: An ester of formula (I) (where m is an integer from 1 to 10 and n is an integer from 0 to 8) is converted to a corresponding trioxane derivative by heating in the presence of a specific catalyst.SELECTED DRAWING: None
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Citation Information
Patent Citations
JP2023090657A
US20170233366A1