ORAL ADMINISTRATION OF ANTISIAN CONJUGATES TARGETING PCSK9

MA61691B2Active Publication Date: 2026-06-30CIVI BIOPHARMA INC
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Patent Information

Application Number
MA61691
Authority / Receiving Office
MA · MA
Patent Type
Patents
Current Assignee / Owner
Priority Date
2021-12-10
Filing Date
2023-07-07
Publication Date
2026-06-30
Estimated Expiration
2043-07-07
Patent Text Reader

Abstract

The present disclosure provides pharmaceutic compositions for oral delivery comprising an antisense oligonucleotide (e.g., CIVI 008) and an oral delivery agent such as 5-CNAC. In some aspects, the disclosure provides a capsule comprising a dry blend of CIVI 008 and 5-CNAC, and optionally a statin.
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Citation Information

Patent Citations

  • Method of treating cancer

    WO2014046983A1

  • Antisense oligomers and conjugates targeting PCSK9

    WO2014207232A1