Use of phosphoglucose isomerase ospgip1 in regulating plant yield and plant height

By ectopically expressing the OsPGIp1 protein in plants and regulating its expression using the CRISPR/Cas9 system, the problem of regulating starch accumulation and biomass in plants in existing technologies has been solved, resulting in a significant improvement in crop yield and agronomic traits.

WO2026108245A1PCT designated stage Publication Date: 2026-05-28INST OF GENETICS & DEVELOPMENTAL BIOLOGY CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
INST OF GENETICS & DEVELOPMENTAL BIOLOGY CHINESE ACAD OF SCI
Filing Date
2025-08-01
Publication Date
2026-05-28

AI Technical Summary

Technical Problem

Current technologies lack effective means to regulate glucose-6-phosphate isomerase (PGI) activity through genetic engineering to increase crop starch content and biomass, thereby improving grain yield.

Method used

By ectopically expressing the OsPGIp1 protein in plants or regulating the expression of its encoding gene, gene editing using the CRISPR/Cas9 system can reduce or upregulate the expression level of the OsPGIp1 protein, thereby controlling plant height and yield.

Benefits of technology

It significantly increased starch accumulation and biomass in plants, and improved agronomic traits such as crop yield, seed setting rate, effective tillering, and plant height.

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Abstract

Provided in the present application are a glucose 6-phosphate isomerase OsPGIp1 protein and an encoding gene thereof, and use of the protein and a substance for regulating the expression of the encoding gene of the protein in regulating the height, grain weight, effective tiller number, seed-setting rate, or yield of a plant. The rice gene OsPGIp1 can be used for rice genetic breeding, germplasm resource screening, and mechanism research on breeding.
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