Odor binding protein compositions and methods of making and using the same

Abstract

Provided herein are compositions comprising an odor binding protein for non-aerosol formulations intended, to maintain hair and / or skin health of an individual and prolong time between application of such compositions. In some embodiments, the compositions may remove malodors. Also, provided herein are methods of making and using compositions described herein for non-aerosol formulations for maintaining hair and / or skin health.

Description

CROSS REFERENCE

[0001] This application claims the benefit of U.S. Provisional Application Serial No. 63 / 612,211, filed December 19, 2023, and U.S. Provisional Application Serial No. 63 / 667,522 filed on July 3, 2024, each of which is incorporated herein by reference in its entirety. SEQUENCE LISTING [00021 The present application is being filed along with a Sequence Listing in electronic format. The Sequence Listing is provided as a file entitled 63230-728_601_SL.xml, created December 16, 2024, which is 305 kilobytes in size. The information in the electronic format of the Sequence Listing is incorporated by reference in its entirety. BACKGROUND

[0003] Overuse of water and use of volatile organic chemicals tor the preparation of personal care products is wasteful and environmentally unsafe. SUMMARY

[0004] High frequency use of in-shower shampoos by an individual to mitigate scalp malodor and oiliness can expose hair fibers to harmful and damaging agents in tap water (e.g., from a shower or faucet) including but not limited to alkaline pH of tap water, hard water, and trace metals and minerals. In certain instances, repeated use of in-shower shampoos can lead to color loss in trea ted hair. Furthermore, commercially available alternatives to in-shower shampoos, such as styling agents or dry shampoos, are often provided to die hair and / or scalp by aerosol delivery which requires high levels of toxic and environmentally unsafe organic chemicals to be effective and may require special shipping due to pressurization and high flammability. Moreover, in order to formulate aerosol-delivered products (e.g., with propellants) as well as the need for a drier application feel further necessitates inclusion of low levels of water, making incorporation of water-soluble extracts that possess scalp skin benefits challenging. Aerosol-delivered product formulations introduce additional challenges, such as difficulty in controlling product pH upon application. Inclusion of higher levels of powder in aerosol-delivered products aids in oil absorption and odor adsorption, but excess levels can be over-drying to scalp skin without hydrating ingredients causing an itchy or uncomfortable scalp. Incorporation of high levels of fragrance to mask odors can also contribute to scalp irritation.

[0005] In one aspect provided herein are compositions and formulations for application to an individual (e.g., to mitigate scalp malodor and oiliness) that reduce / and or eliminate use of dangerous and environmentally harmful ingredients and damaging agents like organic solvents.

[0006] The above features and methods are of representative embodiments only and are not intended to limit the scope and breadth of the claims.

[0007] In some aspects, provided herein is a composition comprising an odor binding protein comprising a sequence at least about 80% identical to any one of SEQ ID NOS: 1-82, 201-340 and an absorbing agent. In some embodiments, the absorbing agent binds to and / or absorbs oil and sebum. In some embodiments, the absorbing agent, comprises a compound comprising silicon. In some embodiments, the compound comprises silica, a silicate salt, silica silylate, silica dimethyl silylate, silica dimethicone silylate, or a combination of two or more thereof. In some embodiments, the absorbing agent comprises silica. In some embodiments, the absorbing agent comprises a carbonate salt, metal oxide, clay mineral powder, or a combination of two or more thereof. In some embodiments, the absorbing agent is from about 0.01% to about. 40% by weight (w / w) of the composition. In some embodiments, the absorbing agent is from about 1% to about 25% by weight (w / w) of the composition. In some embodiments, the absorbing agent is from about 2% to about 15% by weight (w / w) of the composition. In some embodiments, the absorbing agent comprises silica from about 2% to about 15% by weight (w / w) of the composition. In some embodiments, the composition further comprises a sebum regulating agent. In some embodiments, when applied to hair, the composition maintains or increases a hair property as compared to the hair property of hair not applied with the composition, where the hair property comprises hair strength, hair color, hair elasticity, hair luster, hair porosity, or a combination thereof. In some instances, Ilie hair elasticity is determined by measuring a Young’s Modulus of hair. In some instances, the hair color is determined by a color fade assay. In some instances, the hair strength is determined by a break stress. In some instances, the hair luster is determined by polarized spectroscopy, imaging, or both. In some instances, the hair porosity is determined by measuring a density of hair. In some embodiments, the composition is applied to hair prior to heat application.

[0008] In some aspects, provided herein is a composition comprising an odor binding protein comprising a sequence at least about. 80% identical to any one of SEQ ID NOS: 1-82, 201-340; and a sebum regulating agent. In some embodiments, the sebum regulating agent comprises bioactive compounds for reducing sebum and oil. In some embodiments, the sebum regulating agent, reduces, regulates, or removes sebum and / or sweat. In some embodiments, the sebum regulating agent comprises salicylic acid, microalgae extracts, green tea emulsions, avocado extract, Opuntia ficus-indica stem extract, Anetholea anisate leaf extract, Tetraselmis Suecica extract, Alteromonas ferment extract, Pseudoalteromonas ferment extract, Corylus avellana leaf extract, Phyllanthus emblica fruit extract, Saccharum officinarum (sugarcane) extract, Rhodomyrtus tomentosa fruit extract, Hedychium coronarium root extract, Epiiobium angustifolium flower / Jeaf / stem extract, Tremella fuciformis sporocarp extract, or a combination of two or more thereof. In some embodiments, the sebum regulating agent comprises tetraselmis suecica extract. In some embodiments, the sebum regulating agent is from about 0.0001% to about 1% by weight (w / w) of the composition. In some embodiments, the sebum regulating agent is from about 0.0005% to about 0.5% by weight (w / w) of the composition. In some embodiments, the sebum regulating agent is from about 0.001% to about ¢).05% by weight (w / w) of the composition. In some embodiments, the sebum regulating agent comprises tetraselmis suecica extract from about 0.001% to about 0,05% by weight (w / w) of the composition.

[0009] In some embodiments, the composition has a pH from about 6 to about 9. In some embodiments, the composition has a pH from about 7 to about 7.5.

[0010] In some embodiments, the composition further comprises a buffering agent. In some embodiments, the buffering agent maintains the pH of the composition. In some embodiments, the buffering agent comprises a weak acid, weak base, amino acid, weak organic acid, weak organic base, or combinations of two or more thereof. In some embodiments, the buffering agent comprises citric acid, lactic acid, glycolic acid, malic acid, tartaric acid, arginine, tromethamine, sodium hydroxide, potassium hydroxide, or a combination of two or more thereof. In some embodiments, the buffering agent comprises lactic acid, citric acid, tromethamine (Tris), and arginine.

[0011] In some embodiments, buffering agent is from about 0.001% to about 1% by weight (w / w) of the composition. In some embodiments, the buffering agent is from about 0.005% to about 0.5 by weight (w / w) of the composition. In some embodiments, the buffering agent is from about 0.01% to about 0.1% by weight (w / w) of the composition. In some embodiments, the buffering agent comprises lactic acid from about 0.0005% to about 0.01% by weight (w / w), cihic acid from about 0.01% to about 0.1% (w / w), tromethamine from about 0.001% to about 0.05% (w / w), and arginine from about 0.000075% to about 0.005% (w / w) of the composition.

[0012] In some embodiments, the sequence is at least about 90% identical to any one of SEQ ID NOS: 1-82, 201-340. In some embodiments, the odor binding protein binds to an odorant molecule.

[0013] In some embodiments, the odor binding protein is from about 0.001% to about 1% by weight (w / w) of the composition. In some embodiments, the odor binding protein is from about 0.002.5% to about 0.5% by weight (w / w) of the composition. In some embodiments, the odor binding protein is from about 0.005% to about 0.1% by weight (w / w) of the composition.

[0014] In some embodiments, the composition further comprises a solvent. In some embodiments, the solvent comprises a polar solvent, nonpolar solvent, water, alcohol, polyol, glycol, sugar, polyethylene glycol, or a combination of two or more thereof. In some embodiments, the solvent comprises water, mannitol, dimethyl isosorbide, triethyl citrate, phenethyl benzoate, dicaprylyl maleate, dilinoleic acid / propanediol copolymer, denatured ethanol, denatured methanol, denatured propanol, denatured isopropyl alcohol, denatured butanol, denatured pentanol, denatured hexanol, methanol, ethanol, propanol, isopropyl alcohol, butanol, pentanol, hexanol, glycerin, butylene glycol, isoprene glycol, propylene glycol, dipropylene glycol, propanediol, isopentyldiol, polyethylene glycols, sorbitol, glucose, fructose, maltose, lactose, sucrose, PEG-4, PEG-6, PEG-8, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18, PEG-20, or a combination of two or more thereof. In some embodiments, the solvent comprises water, mannitol, glycerin, and denatured ethanol. In some embodiments, the solvent comprises water and denatured ethanol.

[0015] In some embodiments, the solvent is from about 35% to about 99% by weight (w7w) of the composition. In some embodiments, the solvent is from about 60% to about 97% by weight (w / w) of the composition. In some embodiments, solvent is from about 80% to about 95% by weight (w / w) of the composition. In some embodiments, the solvent comprises water from about 45% to about 85% by weight (w / w), mannitol from about 0.02% to about 0.1% (w / w), glycerin from about 0.1% to about 1% (w / w), and dena tured ethanol from about 10% to about 30%« (wAv) of the composition. In some embodiments, the solvent comprises water from about 45% to about 85% by weight (w / w) and denatured ethanol from about 10% to about 30% (w / w) of the composition.

[0016] In some embodiments, the composition further comprises a humectant. In some embodiments, the humectant comprises a hyaluronate, glycol, sorbitol, sugar, carbocyclic sugar, alcohol, or a combination of two or more thereof. In some embodiments, the humectant comprises 1,2,6 hexanetriol, dipropylene glycol, glycerin, butylene glycol, caprylyl glycol, pentylene glycol, isopentyldiol, hexylene glycol, panthenol, phytantriol, propylene glycol, propanediol, sodium PCA, sorbitol, triethylene glycol, polyglyceryl sorbitol, glucose, fructose, mannitol, xylitol, inositol, trehalose, poly dextrose, potassium PCA, hydrogenated honey, hyaluronic acid, hydrolyzed hyaluronic acid, sodium hyaluronate, inositol, erythritol, capryl glycol, acetamidoethoxyethanol, or a combination of two or more thereof. In some embodiments, the humectant comprises glycerin, mannitol, sodium hyaluronate, and hydrolyzed hyaluronic acid.

[0017] In some embodiments, the humectant is from about 0.01% to about 5% by weight (w / w) of the composition. In some embodiments, the humectant is from abou t from about 0.1% to about 2% by weight (w / w) of the composition. In some embodiments, the humectant is from about 0.25% to about 1% by weight (w / w) of the composition. In some embodiments, the humectant comprises mannitol from about 0.02% to about 0.1% by weight (w / w), glycerin from about 0.1% to about 1% (w / w), sodium hyaluronate from about 0.001% to about 0.01% (w / w), and hydrolyzed hyaluronic acid from about 0.001% to about 0,1% (w / w) of the composition.

[0018] In some embodiments, the composition further comprises a rheology modifying agent. In some embodiments, the rheology modifying agent comprises a hydrocolloid, naturally derived polymer, aqueous natural polymer, sugars, or a combinations of two or more thereof. In some embodiments, the rheology modifying agent comprises pectin, gellan gum, carrageen, glycerin, agar, xanthan gum. pullulan, algin, tetragonoloba (guar) gum, sclerotium gum, acacia Senegal gum, cellulose, cellulose gum, carboxymethylcellulose, carbomer, hydroxypropyl starch phosphate, guar hydroxypropyltrimonium chloride, carboxymethyl hydroxyethyl cellulose, carboxymethyl hydroxypropyl guar, cellulose, ethyl cellulose, hydroxybutyl methylcellulose, hydroxyethylcellulose, hydroxy methylcellulose, lauryl poly glucose, or a combination of two or more thereof. In some embodiments, the rheology modifying agent comprises gelian gum.

[0019] In some embodiments, the rheology modifying agent is from about 0.005% to about 10% by weight (w / w) of the composition. In some embodiments, the rheology modifying agent is from about 0.01 % to about 2% by weight (w / w) of the composition. In some embodiments, the rheology modifying agent is from about 0.05% to about 0.5% by weight (w / w) of tire composition. In some embodiments, the rheology modifying agent comprises gelian gum from about 0.05% to about 0.5% by (w / w) of tire composition.

[0020] In some embodiments, the composition further comprises a stabilizing agent. In some embodiments, the stabilizing agent comprises a salt, sulfate, or a combination of two or more thereof. In some embodiments, the stabilizing agent comprises calcium chloride, magnesium chloride, magnesium sulfate, potassium chloride, potassium glycol sulfate, sodium chloride, or a combination of two or more thereof. In some embodiments, the stabilizing agent comprises sodium chloride.

[0021] In some embodiments, the stabilizing agent is from about 0.005% to about 10% by weight (w / w) of the composition. In some embodiments, the stabilizing agent is from about 0.01% to about 2% by weight (w / w) of the composition. In some embodiments, the stabili zing agent is from about 0.05% to about 0.5% by weight (w / w) of the composition. In some embodiments, the stabilizing agent comprises sodium chloride from about 0.05% to about 0.5% by weight (w / w) of the composition.

[0022] In some embodiments, tire composition further comprises a chelating agent. In some embodiments, the chelating agent comprises EDTA, sodium phytate, sodium gluconate, trisodium dicarboxymethyl alanmate, tetrasodium glutamate diacetate, caprylhydroxamic acid, or a combination of two or more thereof. In some embodiments, the chelating agent comprises sodium phytate. In some embodiments, the chelating agent is from about 0.005% to about 10% by weight (w7wj of the composition. In some embodiments, the chelating agent is from about 0.01% to about 2% by weight (w / w) of the composition. In some embodiments, the chelating agent is from about ¢).05% to about 0.5% by weight (w / w) of the composition. In some embodiments, the chelating comprises sodium phytate from about 0.05% to about 0.5% by weight (w / w) of the composition.

[0023] In some embodiments, the composition further comprises a preservative. In some embodiments, the preservative comprises an alcohol, paraben, formaldehyde release, carbamate, sorbate, or a combination of two or more thereof In some embodiments, the preservative comprises benzyl alcohol, benzoic acid, butyl paraben, diazolidinyl urea, DMDM hydantoin, ethyl paraben, imidazolidinyl urea, iodopropynyl butylcarbamate, isobutyl paraben, methyl paraben, methylchloroisothiazolinone, methylisothiazolinone, phenoxyethanol, propyl paraben, sodium benzoate, potassium sorbate, ethylhexylglycerin, gluconolactone, or a combination of two or more thereof.

[0024] In some embodiments, the preservative comprises benzy1 alcohol. In some embodiments, the preservative is from about 0.005% to about 10% by weight (w / w) of the composition. In some embodiments, the preservative is from about 0.01% to about 5% by weight (w / w) of the composition. In some embodiments, the preservative is from about 0.5% to about 2% by weight (w / w) of tire composition. In some embodiments, tire preservative comprises benzyl alcohol from about 0.5% to about 2% by weight (w / w) of the composition.

[0025] In some embodiments, the composition is a suspension. In some embodiments, the suspension comprises a non-aerosol hydroalcoholic formulation. In some embodiments, tire composition is a hair or scalp composition. In some embodiments, when applied to the hair, the composition maintains or increases the hair property' as compared to the hair property' of hair not applied with the composition. In some embodiments, die composition is applied to the hair prior to heat application.

[0026] In some aspects, provided herein is a method for reducing malodor of a hair and / or scalp of an individual, tire method comprising administering an effective amount of tire composition as described herein to the hair and / or scalp of the individual.

[0027] In some embodiments, provided herein is a method for reducing sebum in a hair and / or scalp of an individual, the method comprising administering an effective amount of the composition as described herein to die hair and / or scalp of the individual.

[0028] In some embodiments, provided herein is a method for reducing sebum on a hair and / or scalp of an individual, the method comprising administering an effective amount of a composition comprising an odor binding protein to tire hair and scalp of the individual, wherein the odor binding protein comprises a sequence at least about 80% identical to any one of SEQ ID NOS: 1-82, 201 -340.

[0029] In some embodiments, the composition further comprises an absorbing agent.

[0030] In some embodiments, the composition further comprises a sebum reducing agent.

[0031] In some embodiments, skin surface levels of sebum are reduced compared to a baseline measurement for about 24 to about 72 hours or more after administration of tire composition. In some embodiments, sebum reduction is measured by a Sebumeter. In some embodiments, when measured immediately after administration compared to a baseline measurement, sebum is reduced about 1 to about 20 pg / cm2. In some embodiments, when measured immediately after administration compared to a baseline measurement, sebum is reduced about 5 to about 15 pg / cm2. In some embodiments, when measured immediately after administration compared to a baseline measurement, sebum is reduced by about 10 pg / cm2. In some embodiments, when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced about I to about 19 pg / cm2. In some embodiments, when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced about 4 to about 14 pg / cm2. In some embodiments, when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced by about 9 pg / cm2. In some embodiments, when measured about 24 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 17 pg / cm2. In some embodiments, when measured about 24 hours after administration compared to a baseline measurement, sebum is reduced about 3 to about 12 pg / cm2. In some embodiments, when measured about 24 hours after administration compared to a baseline measurement, sebum is reduced by about 7 pg / cm2. In some embodiments, when measured about 48 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 15 pg / cm2. In some embodiments, when measured about 48 hours after administration compared to a baseline measurement, sebum is reduced about 2 to about 10 pg / cm2. In some embodiments, when measured about 48 hours after administration compared to a baseline measurement, sebum is reduced by about 5.5 pg / cm2. In some embodiments, when measured about 72 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 8 pg / cm2'. In some embodiments, when measured about 72 hours after administration compared to a baseline measurement, sebum is reduced about 2 to about 6 pg / cm2. In some embodiments, when measured about 72 hours after administration compared to a baseline measurement, sebum is reduced by about 4 pg / cm2.

[0032] In some aspects, provided herein is a method for reducing malodor on a hair and / or scalp of an individual, the method comprising administering an effective amount of a composition comprising an odor binding protein to the hair and scalp of the individual, wherein the odor binding protein comprises a sequence at least about 80% identical to any one of SEQ ID NOS: 1-82, 201 -340. In some embodiments, the composition further comprises an absorbing agent. In some embodiments, the composition further comprises a sebum reducing agent. In some embodiments, malodor levels are reduced compared to a baseline measurement for about 24 to about 72 hours or more after administration of the composition. In some embodiments, malodor levels are evaluated by a trained odor grader on a scale of 0 to 10. In some embodiments, when measured immediately after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 7 on the scale. In some embodiments, when measured immediately after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 6 on the scale. In some embodiments, when measured immediately after administration compared to a baseline measurement, malodor levels are reduced by about 5 on the scale. In some embodiments, when measured about 12 hours after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 7 on the scale. In some embodiments, when measured about 12 hours after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 6 on the scale. In some embodiments, when measured about 12 hours after administration compared to a baseline measurement, malodor levels are reduced by about 5 on the scale. In some embodiments, when measured about 24 hours after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 6 on the scale. In some embodiments, when measured about 24 hours after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 5 on the scale. In some embodiments, when measured about 24 horns after administration compared to a baseline measurement, malodor levels are reduced by about 4 on the scale. In some embodiments, when measured about 48 hours after administration compared to a baseline measurement, malodor levels are reduced about 2. to about 5 on the scale. In some embodiments, when measured about 48 hours after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 4 on the scale. In some embodiments, when measured about 48 hours after administration compared to a baseline measurement, malodor levels are reduced by about 3.5 on the scale. In some embodiments, when measured about 72 hours after administration compared to a baseline measurement, malodor levels are reduced about 1 to about 4 on the scale. In some embodiments, when measured about. 72 hours after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 3 on the scale. In some embodiments, when measured about 72 hours after administration compared to a baseline measurement, malodor levels are reduced by about 2.5 on tire scale.

[0033] In some embodiments, when applied to the hair, the composition maintains or increases a hair property as compared to the hair property of hair not applied with the composition. In some embodiments, the composition described herein is applied to the hair prior to heat, application. DETAILED DESCRIPTION

[0034] Provided herein are compositions (e.g., for application to the hair and / or skin of individuals), as well as methods of making and using such compositions. In certain embodiments, any composition provided herein can comprise formulations (e.g,, non-aerosol, hydroalcoholic formulations) for application to the hair and / or skin of individuals. In specific embodiments, compositions provided herein comprise non-aerosol, hydroalcoholic formulations. In some instances, compositions provided herein are useful in prolonging time between washing the hair of an individual without comprising scalp comfort and maintaining scalp health. In certain instances, such compositions are useful in addressing such aspects while meeting volatile organic compound (VOC) reduction requirements.

[0035] In some embodiments, provided herein are compositions (e.g., provided to the hair and / or scalp of an individual) comprising an odor binding protein (e.g., such as a peptide comprising a sequence at least about 80% identical to any one of SEQ ID NOS: 1-82, 201-340). In certain embodiments, provided herein are compositions comprising an odor binding protein and an absorbing agent. In some embodiments, provided herein are compositions comprising an odor binding protein and a sebum regulating agent.

[0036] In some embodiments, provided herein are compositions (e.g., provided to the hair and / or scalp of an individual) comprising an odor binding protein (e.g., such as a peptide comprising a sequence at least about 80% identical to any one of SEQ ID NOS: 1 -82, 201-340). In certain embodiments, provided herein are compositions comprising an odor binding protein and an absorbing agent. In some embodiments, the composition maintains or increases a hair property where applied, e.g., hair and / or skin of individuals, relative to hair or and / or skin not applied with the composition described herein. In some embodiments, the composition maintains a hair property where applied, e.g., hair anchor skin of individuals, relative to hair or and / or skin not applied with the composition described herein. In some embodiments, the composition increases a hair property where applied, e.g., hair and / or skin of individuals, relative to hair or and / or skin not applied with the composition described herein. In some embodiments, the composition is applied to the hair prior to heat application. In some embodiments, the hair property of hair applied with the composition is greater than a hair property of hair not applied with the composition.

[0037] As used herein, in some instances, hair property refers to various aspects of hair characteristics, e.g., hair strength, hair color, hair elasticity, hair luster, hair porosity, or a combination thereof. In some instances, tire hair property comprises hair strength, hair color, hair elasticity, hair luster, hair porosity, or a combination thereof. In some instances, the hair property can be determined using appropriate tests or measurements. In some instances, the hair elasticity is determined by measuring a Young’s Modulus of hair. In some instances, the hair color is determined by a color fade assay. In some instances, the hair strength is determined by a break stress. In some instances, die hair luster is determined by polarized spectroscopy, imaging, or both. In some instances, the hair porosity is determined by measuring a density7 of hair.

[0038] In some embodiments, any composition provided herein comprises one or more additional agents (such as a solvent, humectant, preservative, chelating agent, stabilizing agent, buffering agent, rheology modifying agent, sebum regulating agent, fragrance, excipients and the like). In certain instances, addition of one or more additional agents to any composition provided herein improve absorption of (e.g., odor binding proteins in) compositions provided herein. [0039^ In certain embodiments, the pH of a composition (e.g., a composition provided herein) is adjusted (e.g., using an acid, base, and / or buffer). In some embodiments, the pH of any composition provided herein is adjusted and / or maintained with a buffering agent (e.g., a buffering agent provided herein). In some instances, pH of a composition provided herein is important for the components of the composition to function properly (e.g., odor binding protein, absorbing agents, sebum regulating agents, and / or the like). In specific embodiments, a buffering agent (e.g., a buffering agent provided herein) is used to raise die pH of the composition. In yet more specific embodiments, a buffering agent (e.g., a buffering agent provided herein) is used to lower the pH of tlie composition.

[0040] In certain embodiments, pH of a composition (e.g., a composition provided herein) is adjusted to a pH from about 6 to about 9. In some embodiments, pH of a composition (e.g., a composition provided herein) is adjusted to a pH from about 6.5 to about 8.5. In certain embodiment, pH of a composition (e.g., a composition provided herein) is adjusted to a pH from about 6.8 to about 8.2. In specific embodiments, pH of a composition (e.g., a composition provided herein) is adjusted to a pH from about 7 to about 7.5. In yet more specific embodiments, pH of a composition (e.g., prior to adding an odor binding protein) is adjusted to a pH from about 6.8 to about 7.2. In still more specific embodiments, pH of a composition (e.g., a non-aerosol, hydroalcoholic formulation of a composition provided herein) is adjusted to a pH from about 7 to about 7.5. In yet more specific embodiments, pH of a composition (e.g., a non-aerosol, hydroalcoholic formulation of a composition provided herein) is adjusted to a pH no more than about 7.5. In yet more specific embodiments, pH of a composition (e.g., a non-aerosol, hydroalcoholic formulation of a composition provided herein) is adjusted to a pH no less than about 7.

[0041] In certain embodiments, application of a composition (e.g., a composition provided herein provided to the hair and / or skin of an individual) reduces malodor levels where applied, when compared to a baseline measurement. In certain instances, malodor levels are evaluated by trained odor graders (e.g., such as provided herein in Table 2). In some instances, baseline measurement refers to the malodor levels measured in the hair and / or skin of individuals that refrained from washing their hair and refrained from using any hair or scalp products tor tour days prior to testing and prior to administration of a composition (e.g., non-aerosol, hydroalcoholic formulations of compositions provided herein). In certain instances, the mean odor difference compared to the baseline measurement persists for about 24 to about 72. hours or more after administration. In certain instances, the mean odor difference compared to the baseline measurement is maintained at a sustained level immediately after administration to about 24 hours after administration.

[0042] In specific embodiments, the mean odor difference compared to the baseline measurement in individuals administered compositions provided herein when measured immediately after administration comprises a reduction of about 2 to about 7. In yet more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured immediately after administration comprises a reduction of about 3 to about 6. In still more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured immediately after administration comprises a reduction of about 5.

[0043] In yet more specific embodiments, tire mean odor difference compared to tire baseline measurement in individuals when measured about 12 hours after administration comprises a reduction of about to 2 to about 7. In still more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 12 hours after administration comprises a reduetion of about 3 to about 6. In yet more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 12 hours after administration comprises a reduction of about 5.

[0044] In still more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 24 hours after administration comprises a reduction of about 2 to about 6. In yet more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 24 hours after administration comprises a reduction of about 3 to about 5. In still more specific embodiments, the mean odor difference compared to tire baseline measurement m individuals when measured about 24 hours after administration comprises a reduction of about 4.

[0045] In yet more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 48 hours after administration comprises a reduction of about 2 to about 5. In still more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 48 hours after administration comprises a reduction of about 3 to about 4. In yet more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 48 hours after administration comprises a reduction of about 3.5.

[0046] In still more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 72 hours after administration comprises a reduction of about 1 to about 4. In yet more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 72 hours after administration comprises a reduction of about 2 to 3. In still more specific embodiments, the mean odor difference compared to the baseline measurement in individuals when measured about 72 hours after administration comprises a reduction of about 2.5.

[0047] In certain embodiments, application of a composition (e.g., a composition provided herein provided to the hair and / or skin of an individual) reduces sebum levels when compared to a baseline measurement. In certain embodiments, sebum is measured with any suitable device or technique (e.g., a Sebumeter). In some instances, sebum levels are measured with a Sebumeter, a device used to assess skin surface sebum levels on an individual. A Sebumeter measures sebum by application of a specialized probe composed of a sebum sensitive film on its surface and results are expressed in g / cm2, mg / cm2, pg / cm2, and the like. In some instances, sebum levels are measured with Sebutape, a measurement technique used to assess the seborrheic activity of skin pores in an individual. Sebutape measurement is performed by applying a patch of a transparent film that collects skin surface sebum. Active pores filled of sebum block the light and form spots on the film which is subsequently analyzed by image analysis or visually using a graded scale.

[0048] In certain embodiments, baseline measurement refers to the amount of sebum measured in individuals that refrained from washing their hair and using any hair or scalp products for four days prior to testing and prior to administration of a composition (e.g., non-aerosol, hydroalcoholic formulations of compositions provided herein). In certain instances, the mean sebum difference compared to the baseline measurement persists for about 24 to about 72 hours or more after administration. In certain instances, the mean sebum difference compared to the baseline measurement is maintained at a sustained level immediately after administration to about 24 hours after administration.

[0049] In specific embodiments, the mean sebum difference compared to the baseline measurement in individuals administered compositions provided herein when measured immediately after administration comprises a reduction of about 1 to about 20 pg / cm2. In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured immediately after administration comprises a reduction of about 5 to about 15 pg / cm2. In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured immediately after administration comprises a reduction of about 10 pg / cm2.

[0050] In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 12 hours after administration comprises a reduction of about to 1 to about 19 pg / cm2. In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 12 hours after administration comprises a reduction of about 5 to about 14 pg / cm2. In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 12 hours after administration comprises a reduction of about 9 pg / cm2.

[0051] In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 24 hours after administration comprises a reduction of about 1 to about 17 pg / cm2 In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 24 hours after administration comprises a reduction of about 3 to about 12 ug / cm2. In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 24 hours after administration comprises a reduction of about 7 pg / cm2.

[0052] In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 48 hours after administration comprises a reduction of about 1 to about 15 pg / cm2. In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 48 hours after administration comprises a reduction of about 2 to about 10 ug / cm2. In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 48 hours after administration comprises a reduction of about 5.5 pg / cm2.

[0053] In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 72 hours after administration comprises a reduction of about 1 to about 8 ug / cm2. In yet more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 72 hours after administration comprises a reduction of about 2 to 6 pg / cm2. In still more specific embodiments, the mean sebum difference compared to the baseline measurement in individuals when measured about 72 hours after administration comprises a reduction of about 4 pg / cm2.

[0054] In some embodiments, application of a composition (e.g., a composition provided herein provided to tire hair and / or skin of an individual) protects the area where the composition is applied, e.g., hair and / or skin of individuals. In some embodiments, application of a composition (e.g., a composition provided herein provided to the hair and / or skin of an individual) increases or maintains a hair property of hair or scalp as compared to the hair property of hair or scalp not applied with the composition. In some embodiments, application of a composition (e.g., a composition provided herein provided to the hair and / or skin of an individual) increases a hair property of hair or scalp as compared to the hair property of hair or scalp not applied with the composition. In some embodiments, application of a composition (e.g., a composition provided herein provided to the hair and / or skin of an individual) maintains a hair property of hair or scalp as compared to the hair property of hair or scalp not applied with the composition. In some embodiments, application of a composition (e.g., a composition provided herein provided to the hair and / or skin of an individual) increases a hair property' where applied, when compared to a baseline measurement. In some instances, as described herein, the hair property refers to various aspects of hair characteristics, e.g., hair strength, hair color, hair elasticity, hair luster, hair porosity, or a combination thereof.

[0055] In some instances, the hair property can be determined using appropriate tests or measurements. In some instances, the hair elasticity is determined by measuring a Young’s Modulus of hair. In certain embodiments, the Young’s Modulus is measured using a tensiometer. In some instances, the hair color is determined by a color fade assay. In some instances, the hair strength is determined by a break stress. In certain embodiments, die break stress is measured using a tensiometer. In some instances, the hair luster is determined by polarized spectroscopy, imaging (e.g., scanning electron microscopy (SEM)), or both. In some instances, die hair porosity is determined by measuring a density of hair. In some embodiments, hair porosity is determined by a strand test, wherein hair is submerged in water.

[0056] In some embodiments, the composition is applied to the hair prior to heat application. In some instances, as described herein, the heat application comprises exposing of hair and / or skin of an individual to heat such as using a hair styling tool, including but not limited to, hair dryer (or hood dryer), blow-dryer, straightener (e.g., flat iron), curling iron, curling wand, styler, heated brush / comb, etc., or a combination thereof. In some embodiments, tire heat application comprises hair styling tools comprising a dryer, a straightener, a curling iron, a styler, a heated brush, or a heated comb. In some instances, application of the composition reduces damage caused by heat application.

[0057] In certain embodiments, compositions (e.g., compositions provided herein) are formulated as products for use by individuals. In some embodiments, compositions provided herein are formulated as products such as deodorants, shampoos, conditioners, hair conditioners, hair shampoos, dry shampoos, dry conditioners, leave in conditioners, hair masks, face washes, sunscreens, body washes, hand lotions, body lotions, face lotions, body moisturizers, face moisturizers, hair products, makeup removers, shaving creams, shaving gels, lip balms, hair styling products, and the like. In specific embodiments, a composition (e.g., a composition provided herein) is formulated as a hair product. In yet more specific embodiments, a composition (e.g., a composition provided herein) is formulated as a hair product (e.g., a dry shampoo). In still more specific embodiments, a composition (e.g., a composition provided herein) is formulated as a dry shampoo. In yet more specific embodiments, a composition (e.g., a composition provided herein) is formulated as a deodorant. In still more specific embodiments, a composition (e.g., a composition provided herein) is formulated as a hygiene product (e.g., a body wash). In some embodiments, compositions are formulated as a body deodorizer, a body wipe, a hair styling product, a hand soap, a foot cream, a foot soak, a bath bomb, a bath salt, a body scrub, a face mask, an underarm mask, a hair perfume, a style refresher, or scalp refresher, or a combination of two or more thereof.

[0058] In some embodiments, the compositions (e.g., compositions provided herein) are formulated as a product for administering to hair prior to heat application. In some instances, the compositions reduce damage caused by heat application. In some embodiments, damage caused by heat application comprises decreasing a hair property comprising decreasing hair strength, decreasing hair color, decreasing hair elasticity, decreasing hair luster, decreasing hair porosity, or a combination thereof. In some embodiments, damage caused by heat application comprises decreasing a hair property comprising decreasing hair strength, decreasing hair elasticity', decreasing hair luster, decreasing hair porosity', or a combination thereof. In some embodiments, the decreasing hair elasticity comprises reducing heat-induced conversion of alpha-keratin (a-keratin) to betakeratin (p-keratin).

[0059] In some embodiments, application of the composition reduces conversion of a-keratin to p-keratin by about 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, or 100%. In some embodiments, application of the composition reduces conversion of a-keratin to P-keratin by at least 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, or 100%. In some embodiments, application of the composition reduces conversion of a-keratin to p-keratin by at most 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, or 100%. In some embodiments, application of the composition reduces conversion of a-keratin to b-keratm by about 10% to about 100%, about 20% to about 100%, about 30% to about 100%, about 40% to about 100%, about 50% to about 100%, about 60% to about 100%, about 70% to about 100%, about 80% to about 100%, or about 90% to about 100%.

[0060] In some embodiments, the amount of a-keratin, p-keratin, or both is determined by circular dichroism (CD), wide-angle x-ray scattering (WAXS), or both.

[0061] In some embodiments, hair applied with the composition maintains hair porosity as compared to hair not applied with tire composition. In some embodiments, porosity of hair is determined by measuring a density of hair. In some embodiments, hair porosity is determined byplacing a tress of hair applied with the composition and treated with heat in water, wherein if the tress of hair sinks, then the hair is not porous. Conversely, in some instances, if the tress of hair floats, then the hair is porous. In some embodiments, if the tress of hair floats, then the hair is porous, and the tress of hair is determined to be heat damaged. In some embodiments, die tress of hair treated with the composition described herein has the same porosity as compared to a tress of hair not treated with the composition and not treated with heat.

[0062] In certain embodiments, compositions (e.g., compositions provided herein) and formulations of such compositions are prepared using any suitable method (e.g., by combining composition components in suitable sequence and amount under suitable conditions (e.g., such as temperature, pH, and the like)). In specific embodiments, compositions (e.g., compositions provided herein) are prepared with particular process instructions (e.g., such as provided in Example 2). In certain embodiments, compositions provided herein are formulated as suspensions (e.g., such that that active components of compositions are uniformly distributed throughout). In some embodiments, compositions (e.g., compositions provided herein) are formulated as non-aerosol formulations (e.g., using any suitable method). In specific embodiments, compositions provided herein are formulated as non-aerosol, high power content gel biphase formulations. In yet more specific embodiments, compositions provided herein are formulated as hydroalcoholic, high power content gel biphase formulations. In still more specific embodiments, compositions provided herein are formulated as non-aerosol, hydroalcoholic, high powder content gel biphase formulations.

[0063] In some embodiments, the OBP is modified to combine tire binding abilities of a native OBP with an additional domain. In some cases, the additional domain enhances the OBP’s binding strength to hair fibers.

[0064] In one aspect, compositions (e.g., a composition provided herein) comprise an odor binding protein (OBP). In some embodiments, the OBP is produced through recombinant protein production techniques. In some embodiments, the OBP selectively binds to and removes an odorous compound, e.g., in the same or similar manner to its native counterpart found in a mammals' nasal cavity. Native OBPs belong to the lipocalin protein supergroup, with a three-dimensional beta-barrel structure that effectively traps specific odors through non-covalent interactions. In some embodiments, the OBP herein traps odors through non-covalent interactions.

[0065] In some embodiments, OBP liberates a fragrance compound when it is in the presences of higher concentrations of certain odor compounds. In some cases, the OBP has a different binding affinity to different compounds based on specific delta G binding energies. Some compounds have stronger negative delta G values meaning stronger binding to the OBP, Examples of the relevant human odor compounds such isovaleric acid and skatole with good binding energies. In some cases, the OBP enhances the delivery of fragrance compounds due to competitive binding effects.

[0066] In some embodiments, the OBP disclosed herein comprise an odor-binding protein (OBP) or an odor-like binding peptide. In some embodiments, the odor-like binding peptide refers to a peptide, including a synthetic peptide, having a similar secondary structure, tertiary structure, or amino acid sequence, or a combination of two or more thereof, to a wild-type OBP (e.g,, any one of SEQ ID NOS: 1-20), or a fragment of a wild-type OBP. Table 3 provides example embodiments of OBP. In some embodiments, a fragment includes a sequence having at least 4, 5, 6, 7, 8, 9, or 10 amino acids 100% identical to a sequence of wild-type OBP. Non-limiting examples of OBP include SEQ ID NOS: 1-82.

[0067] In some embodiments, the OBP comprises an isolated or artificial unmodified protein with at least 90% of identity to an ammo acid sequence selected from any one of SEQ ID NOS: 182, or mixtures thereof, e.g., 91% identical, 92% identical, 93% identical, 94% identical, 95% identical, 96% identical, 97% identical, 98% identical, 99% identical or 100% identical.

[0068] In some embodiments, the OBP comprises an isolated or artificial unmodified protein with at least 80% of identity to an ammo acid sequence selected from any one of SEQ ID NOS: 182, or mixtures thereof, e.g., 81% identical, 82% identical, 83% identical, 84% identical, 85% identical, 86% identical, 87% identical, 88% identical, or 99% identical.

[0069] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 1. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3. In some embodiments, tire OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6. In some embodiments, tire OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9. In some embodiments, tire OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%. 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 20. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 21-82.

[0070] In some embodiments, the OBP is a fusion protein comprising an OBP region and a keratin or keratin-like peptide. The OBP region may have a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 1-82. The fusion protein may bind to an odor compound. The fusion protein may bind with hair, skin, and / or nails. The fusion protein may bind with high affinity. The fusion protein may repair keratinous fiber damage through the formation of new disulfide bonds between tire fusion protein and the keratin. The fusion protein may have a sequence comprising one or more cysteine amino acids. The one or more cysteine amino acids may form one or more disulfide bonds with one or more cysteine amino acids in the hair, skin, and / or nails. The formation of new disulfide bonds may help to restore the mechanical properties of the hair, skin, and / or nails. The formation of new disulfide bonds may improve elasticity, resistance, and / or appearance of hair. The keratin or keratin-like peptide may have a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%. 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In some embodiments, the fusion protein comprises the OBP connected to the keratin, keratin-like peptide or keratin associated protein via a linker. The linker may be an amino acid linker.

[0071] In some embodiments, the fusion protein comprises a wild-type keratin peptide, a functional fragment of a wild-type keratin peptide, or a peptide having at least 90% identity to a wild-type keratin peptide or a functional fragment of a wild-type keratin peptide. The -wild-type keratin peptide may be keratin 85 having SEQ ID NO: 90. The wild-type peptide keratin peptide may comprise SEQ ID NO: 91, 92, 93, 94 or 95. In some embodiments, the fusion protein forms one or more disulfide bonds wuth hair. In some embodiments, the fusion protein forms one or more disulfide bonds with skin. In some embodiments, the fusion protein forms one or more disulfide bonds with nails.

[0072] In a non-limiting example embodiment, a functional fragment of a wild-type keratin peptide comprises at least 6, 7, 8, 9, 10, II, 12, 13, 14, 15, or 16 contiguous amino acids of a wdld-type keratin peptide. In a non-limiting example embodiment, a functional fragment of a wild-type keratin peptide comprises at least 6, 7, 8, 9, 10, II, 12, 13, 14, 15, or 16 amino acids having at least 90% identity to a wild-type keratin peptide. In a non-limiting example embodiment, a functional fragment of a wild-type keratin peptide comprises at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16 amino acids, where the at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16 amino acids comprise one or more cysteine amino acids. For instance, the one or more cysteine amino acids is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 223, 24, 25, 26 or 27 cysteine amino acids. In a non-limiting example embodiment, a functional fragment of a wild-type keratin peptide comprises at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16 amino acids, where at least 10%, 11%, 12%, 13%, 14%. 15%, 16%, 17%, 18%, 19%, 20%, 30%, 40%, or 50% of the at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16 ammo acids are cysteine amino acids. A non-limiting example embodiment of a keratin or keratin peptide is provided in SEQ ID NO: 90. Table 11 provides example embodiments of keratin and keratin-like peptides.

[0073] In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 6-16 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 6 residues. In some embodiments, tire number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 7 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 8 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 9 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 10 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of tire fusion protein is 11 residues. In some embodiments, the number of ammo acids in the keratin or keratin associated peptide component of the fusion protein is 12 residues. In some embodiments, the number of amino acids m the keratin or keratin associated peptide component of tire fusion protein is 13 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 14 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of die fusion protein is 15 residues. In some embodiments, the number of amino acids in the keratin or keratin associated peptide component of the fusion protein is 16 residues.

[0074] In some embodiments, the keratin or keratin associated peptide of the fusion protein possess a high cysteine content in order to enrich certain properties of the keratin or keratin associated peptide, such as, for example, to enhance formation of intermolecular cross-linking. The total cysteine content may range from about 1% to about 10% of the total number of amino acids in the fusion protein. The total cysteine content may range from about 5% to about 40% of the total number of amino acids in the keratin or keratin associated peptide of the fusion protein. In some embodiments, the keratin or keratin associated peptide of the fusion protein / peptide comprises 2 cysteine residues. In some embodiments, the keratin or keratin associated peptide of the fusion protein comprises 3 cysteine residues. In some embodiments, the keratin or keratin associated peptide of the fission protein comprises 4 cysteine residues. In some embodiments, the keratin or keratin associated peptide of the fusion protein comprises 5 cysteine residues.

[0075] In some embodiments, the keratin or keratin associated peptide of the fusion protein / peptide comprises the peptide sequence (X3)kC(X3)5C(X3)k.

[0076] In some embodiments, each -‘X3” is independently glycine, alanine, valine, isoleucine, leucine, phenylalanine, proline, serine, threonine, asparagine, glutamine, cysteine, methionine, phenylalanine, tyrosine, tryptophan, aspartate, glutamate, histidine, lysine, or arginine.

[0077] In some embodiments, each ‘"k’' is independently an integer ranging from 0 to 3. If k is 2, then (X3)k has a first X3 and a second X3, where each X3 is independently glycine, alanine, valine, isoleucine, leucine, phenylalanine, proline, serine, threonine, asparagine, glutamine, cysteine, methionine, phenylalanine, tyrosine, tryptophan, aspartate, glutamate, histidine, lysine, or argmine. If k is 3, then (X3)k has a first X3, a second X3, and a third X3, where each X3 is independently glycine, alanine, valine, isoleucine, leucine, phenylalanine, proline, serine, threonine, asparagine, glutamine, cysteine, methionine, phenylalanine, tyrosine, tryptophan, aspartate, glutamate, histidine, lysine, or arginine. (X3)5 has a first X3, a second X3, a third X3, a fourth X3, and a fifth X3, where each X3 is independently glycine, alanine, valine, isoleucine, leucine, phenylalanine, proline, serine, threonine, asparagine, glutamine, cysteine, methionine, phenylalanine, tyrosine, tryptophan, aspartate, glutamate, histidine, lysine, or arginine.

[0078] In some embodiments, the keratin or keratin associated peptide component, of the fusion protein comprises: GGVCGPSPPC1TT (SEQ ID NO: 91), GGVCGPSPPC (SEQ ID NO: 92), CGPSPPCITT (SEQ ID NO: 93), CGPSPPC (SEQ ID NO: 94), GVCGPSPPC (SEQ ID NO: 95), or a sequence of SEQ ID NOS: 96-112, or a combination of two or more thereof.

[0079] In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 91. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 92. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 93. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 94. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 95. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 96. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 97. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 98. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 99. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 100. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 101. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 102. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 103, In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 104. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 105. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 106. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 107. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 108. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 109. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 110. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 111. In some embodiments, the keratin or keratin associated peptide sequence comprises SEQ ID NO: 112,

[0080] In some embodiments, a keratin associated peptide includes a peptide that forms a disulfide bond with wild-type keratin. In some embodiments, a keratin associated peptide comprises about or at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16 ammo acids, and the about or at least 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, or 16 amino acids are at least 90% identical to a wild-type keratin peptide sequence. The wild-type keratin peptide may be keratin 85 having SEQ ID NO: 90. The wild-type peptide keratin peptide may comprise SEQ ID NO: 91, 92, 93, 94, or 95.

[0081] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%. 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 1, and a sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 1, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In anon-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: I, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%. 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 1, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 1, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 1, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%. 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0082] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises die sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, die OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0083] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises Ilie sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In anon-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%. 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 3, and die sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0084] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4, and the sequence about or at least about 80%, 81%. 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 4, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0085] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises die sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92, In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 5, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%. 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0086] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises die sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, die OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 6, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0087] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%. 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises Ilie sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In anon-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%. 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 7, and die sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95. JOOSS]    In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 8, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0089] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises die sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a non-iimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92, In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 9, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%. 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0090] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises tire sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 10, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0091] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%. 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In anon-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%. or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%. 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 11, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0092] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12, and the sequence about or at least about 80%, 81%. 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 12, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0093] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises tiie sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93, In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 13, and the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0094] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises tire sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 14, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0095] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%. 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In anon-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%. 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 15, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0096] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID N O: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 16, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0097] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises tiie sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a non-hmiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92, In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93, In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 17, and the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95. [009§] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-Iimitmg example, the OBP comprises tire sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 18, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0099] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%. 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%. 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In anon-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%. 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%. 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%. 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%. 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%. 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 19, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95. JO 100] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 20, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 91-112. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 20, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91. In a nonlimiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 20, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 20, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 2.0, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%. 88%, 89%, 90%, 91%, 92%, 93%, 94%. 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94. In a non-limiting example, the OBP comprises the sequence about or at least about 80%, 81%, 82%, 83%. 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%. 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 20, and the sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 95.

[0101] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 91, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 1-82.

[0102] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 92, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 1-82.

[0103] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%. 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 93, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 1-82.

[0104] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 94, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 1-82. [GIOS] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identieal to SEQ ID NO: 95, and a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 1-82.

[0106] In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to any one of SEQ ID NOS: 2.01-340. In some embodiments, (XI) comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 401. In some embodiments, (XI) comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 402. In some embodiments, (XI) comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 403, In some embodiments, (XI) comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 404. In some embodiments, (XI) comprises LA of Table 13. In some embodiments, (XI) comprises LB of Table 13. In some embodiments, (XI ) comprises LC of Table 13. In some embodiments, (XI) comprises LD of Table 13.

[0107] In some embodiments, the OBP comprises a linker, e.g., a linker between the OBP region and the keratin or keratin like peptide. In some embodiments, the OBP comprises a sequence about or at least, about. 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 401. In some embodiments, the linker comprises a sequence about or at. least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 401. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 402. In some embodiments, the linker comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 402. In some embodiments, the OBP comprises a sequence about or at. least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 403. In some embodiments, the linker comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 403. In some embodiments, the OBP comprises a sequence about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 404. In some embodiments, the linker comprises a sequence about or at least about 80%, 81%, 82%. 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to SEQ ID NO: 404. In some embodiments, the linker comprises LA of Table 13. In some embodiments, the linker comprises LB of Table 13. In some embodiments, the linker comprises LC of Table 13. In some embodiments, the linker comprises LD of Table 13. Table 10. Non-Limiting Example OBP Sequences SEQ ID NO Sequences Odor / odor-like binding proteins 1 Pig OBP QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA Q MKTI.JLGVTLGLAAALSFTLEEE.DITGTWYVKAMVVDKDFP PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYL QELPGTDD^FYCKDQRRGGLRYNIGKLVGRNPNTNLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEH 3 Human OBPlIb MKTLFLGVTLGIAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMY LQELPRRDH.YI.FYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSC1VPEH 4 Mouse OBP M AKFLLLALTFGL AHA AMEGPWKTV Al A ADRVDKIERGGELRIY CR SLICE KECKEMKVTFYVNENGQCSLTin%YLQEDGK.TYKTQFQGNNRYKLVDES PENLTFYSENVDR.ADRKTKLLFrLGHGPErSEQKEKFAELAEEKGIPAGNlRE VLITDYCPE 5 Mouse OBP2A MKSLLLTILLLGLVAVLKAQEAPPDDLVDYSGIWYAKAM.VHNGTLPSHKIP SIVFPVRIIALEECi-DLETTVVFWNNGIlCREFKFVMKKTEEPGKYTAFHNTK VniVEKTSVNEHYWYCEGRHNGTSSFGMGKLMGRDSGENPEAMEEFKNFI KRMNLRLENMFV PEIGDK C VE SD 6 Mouse OBPIB MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDENVDRASRKTKLLYILGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPE 7 Rat OBP HHENLD1SPSEVNGDWRTLY1VADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDI1FFHN VNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQ 8 Rat OBP MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN TFT1LKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSD1KEKFAKLCV AHGURDNIIDLTKTDRCLQA 9 Rat OBP MVKFLLIVLALGVSCAHHENLD1SPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDUFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYN1PNENTQHLVPTDTCNQ 10 Bovine OBP AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKVVKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA HN1NVDKHGQTTEL TGLFVKLNVEDEDLEKFVVKLTEDKGIDKKNVVNFLE NEDHPHPE 11 Boar OBP HKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEH1RVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY SDYV1LHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVE1CQQYGHKFYH DLTKIDRCFQLRGSGGVQESSAE 12 Panda OBP HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN SSLLFNMHIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFR1VETDYTDYI IFHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHG1VKEN1FDLTE VDRCLQARGSEKA 13 Chinese hamster OBP MVKFLLLAFALSVSCAHHKIPEISPSEVDGKWRTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTLT1TFNTKEEGKCQTHTVVGRKDEDGQYKTGFSGNN DFHWEKADGIIIFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLENIAKE FD1SKENIQHLVPTDTCDQ 14 Meishan pig OBP MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 15 Horse OBP MQILLLSLVLGVVCAVQEPQSETDYSLFSGEWNTIYIGSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKWGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTA1IIDIWEDEGGLVTKMVALVGMLGD1QKEDIEKFKEVAKEKEIPEE NIVNIINIDDCPTSE 16 Guinea pig OBP MQILLLALTIGLAYAHQTLDPSEINGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EV1GKKEDAIAFYNHNTDETGKETKMIVVVARRDSLTEEEQQKLQEVAGEK G1PKDNIRYFRERDTCAQ 17 Dog OBP MK1LLLCLILVLACDAHLPLPNVLTQVSGPWKTLYVSSNNLDKIAENGPFRI YIRR1NVD1PRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGR1TKLASLVGRGAHVNEEDIAKFKKLSREKG1P EENII YLGDTDNCPNHE 18 Tibetan pig OBP MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 19 Cat leks OBP RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKV DVDVTNGTWFNFSVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSV TSNTIAiNVNTRRNTTKAFALLDTNGNIFNIGYDSLGSLIIHTANVDTAGQTT QVFALLGKRLHPDDNDFAKFRELMRENNIPEENLIDMSKTEKCPKKEKGTN PS 20 Chimpanzee OBP MALLLLSLGLSLITAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVWVCEKTEKNGEYS1 NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII NLTNKDPCYSKHYRSPPRPPMRE 21 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFWSYASETALITSNTNVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIWIIERDDCPA 22 MKTLJ'LGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYL QELPGTDD^FYCKDQRRGGLRYAIGKLVGRNPNTNLEALEEFKKLVQHK GI.SEEDIFMPLQTGSCVL / EH 23 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRC1QKK1LMRKTEEPGKYSAYGGRKLMY LQELPRRDHYIFYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEH 24 MAKFLLLALTFGLAHAAMEGPWKTVAIAADRVDKIERGGELRIYCRSLTCE KECKEMKVTFYVNENGQCSLTTITGYLQEDGKTYKTQFQGNNRYKLVDES PENLTFYSENVDRADRKTKLLFILGHGPLTSEQKEKFAELAEEGIPAGNIREV L1TDYCPE 25 MKSLLLTILLLGLVAVLKAQEAPPDDLVDYSGIWYAKAMVHNGTLPSHKIP SIVFPVRIIALEEGDLETTWFWNNGHCREFKFVM1<1<TEEPGKYTAFHNT1< VIHVEKTSVNEHYIFYCEGRHNGTSSFGMGKLMGRDSGENPEAMEEFKNFI KRMNLRLENMFVPEIGDKCVESD 26 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDENVDRASRKTKLLYILGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPE 27 HHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFIIN VNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQ 28 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWSIWASDKREKIEENGSM RVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGENT FTILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSDIKEKFAKLCV AHGITRDNIIDLTKTDRCLQA 29 MVKFLI.JrVLAI.JGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDIIFFHNVWDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYNIPNENTQHI.VPTDTCNQ 30 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEGFVD FYFSVKRDGKWNVHVKATQDDGTYVADYEGQNVFKIVSLSRTHLVAHNI NVDHGQTTELTGLFVKLNVEDEDLEFWLTEDGIDNVVNFLEN^ 31 HKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY SDYVILHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVEICGQYGIIKE DLTKIDRCFQLRGSGGVQESSAE 32 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN SSLLFNMHIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFRIVETDYTDYI IFHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHGIVKENIFDLTE VDRCLQARGSEKA 33 MVKFLLIAFALSVSCAHHKIPEISPSEW AYFRHMECSDECQTLTTTFNTKEEGKCQTHTWGRKDEDGQYKTGFSGNN DFHWEKADGIIIHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLENIAKEF DISKENIQHLVPTDTCDQ 34 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 35 MQ1LLLSLVLGVVCAVQEPQSETDYSLFSGEWNTIYIGSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE NIVNIINIDDCPTSE 36 MQTLLLALTIGLAYAHQTLDPSEINGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFWKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EVIGKKEDAIAFYNHNTDETGKETKMIVVVARRDSLTEEEQQKLQEVAGEK GIPKDNIRYFRERDTCAQ 37 MK.TLLLCLILVLACDAHLPLPNVLTQVSGPWKTLWSSNNLDKIAENGPFRI YIRRINVDIPRLKU.FSFFVKVDGECA / 'EKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEEDIAKFKKLSREKGIP EENIIYLGDTDNCPNHE 38 MK.SLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIETDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPEGRLPLPDSHPP LQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKVDVDVTNGTVVFNF SVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSVTSNTIAINVNTRRN TTKAFALLDTNGNIFNIGYDSLGSLIIHTAWDTAGQTTQVFALLGKRLHPD 39 DNDFAKFRELMRENNIPEENLIDMSKTEKCPKKEKGTNPS MALLLLSLGLSLITAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVWVCEKTEKNGEYSI NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII 40 NLTNKDPCYSKHYRSPPRPPMRE QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDWYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ 41 42. GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGGVCGPSPPCITT QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALUSN1NVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQASPIGEGTFDDG PEGWVAYGTDGPLDTSTGALCVAVPAGSAQYGVGWLNGVAIEEGTTYTL RYTATASTDVTVRALVGQNGAPYGTVLDTSPALTSEPRQVTETFTASATYP ATPAADDPEGQIAFQLGGFSADAW TLCLDDVALDSEVEL QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENG1CEEFSEIGTKQEGNTYDVNYAGNNKFWSYASETALIISNINVD 43 EEGDKT1MTGLEGKGTD1EDQDLEKFKEVTRENGIPEENIVNIIERDDCPA QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEG-NTYDVNYAGNNKFVVSYASETALIISNINVD 44 EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAK MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP 45 EENIVNIIERDDCPAK QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNrNVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGGVCGPSPP 46 47 CITT QEPQPEQDPFELSGKWUSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENG1CEEFSEIGTKQEGNTYDVNYAGNNKFWSYASETALIISNINVD EEGDK.TIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIWIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQASPIGEGFFD DGPEGWVAYGTDGPLDTSTGALCVAVPAGSAQYGVGWLNGVAIEEGTT YTLRYTATASTDVTVRALVGQNGAPYGTVLDTSPALTSEPRQVTETFTASA TYPATPAADDPEGQIAFQLGGFSADAWTLCLDDVALDSEVEL, EPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLN FFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALUSN1NVDE 48 EGDKT1MTGLLGKGTDIEDQDLEKFKE VTREN G1PEEN1VN1IERDDCPA 49 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETAEIISNINVDEEGDKT1MTGLLGKGTDTEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 50 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 51 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSTEFDDKESKVYLNFFSKENGTCEEFSLTGTKQEGNTYDVNYAGN KFVVSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRE NGIPEENIVNIIERDDCPAK 52 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKTGENAPFQV FMRSTEFDDKESKVYLNFFSKENGTCEEFSLIGTKQEGNTYDVNYAGNNKFV \S5ASETALUSNINVDEEGDKTIMTGLLGKGTDTEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK. 53 PFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSKENG ICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETAL1ISNINVDEEGDKTIM TGLEGKGTDIEDQDLEKFKEVTRENGIPEENTVNllERDDCPA 54 MKSLLLSLVLGLVCAQEPQPEQDPFEYFFLASGKWITSYIGSSDLEKIGENAP FQVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNN KFVVSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRE NGIPEENIVNIIERDDCPAK 55 MKSLLLSLVLGLVCAQEPQPEQDPFEVRGMGKWITSYIGSSDLEKIGENAPF QVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNN KFVVSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRE NGIPEENIWIIERDDCPAK 56 MKSLLLSLVLGLVCAQEPQPEQDLFELSGKWTTNYTGSSDLEKIGANAPFQ VFMRSTVFDDQESKVYVDFFRKENGTCEEFSLSGTKLEGNTYDVDYVGDNR FVINYASETALILTNINVDEEGNK TVMTGLLGKGTDIEDLEIEKFKEVTRAN GIPEENIVNIIGRDDCPAK 57 QEPQPEQDPFELSGKWITSYIGSSDEEK1GENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALUSN1NVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA 58 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAK 59 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 60 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGGVCGPSPP CITT 61 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSrEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQASPIGEGTFD DGPEGWVAYGTDGPLDTSTGALCVAVPAGSAQYGVGVVLNGVAIEEGTT YTLRYTATASTDVTVRALVGQNGAPYGTVLDTSPALTSEPRQVTETFTASA TYPATPAADDPEGQIAFQLGGFSADAWTLCLDDVALDSEVEL 62 EPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLN FFSKENG1CEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVDE EGD1<TIMTGLLG1<GTDIEDQDLE1<FKEVTRENGIPEENIVNIIERDDCPA 63 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDTEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 64 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 65 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 66 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEK1GENAPFQV FMRS1EFDDKESKVYLNFFSKENG1CEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDTEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 67 PFELSGKWITSYIGSSDLEKTGENAPFQVFMRSTEFDDKESKVYLNFFSKENG ICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVDEEGDKTIM TGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA 68 MKSLLLSLVLGLVCAQEPQPEQDPFEYFFLASGKWITSYIGSSDLEKIGENAP FQVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNN KFVVSYASETALIISNTNVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRE NGIPEENIWIIERDDCPAK 69 MKSLLLSLVLGLVCAQEPQPEQDPFEVRGMGKWITSYIGSSDLEKIGENAPF QVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNN K.FVVSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRE NGIPEENIVNIIERDDCPAK 70 MKSLLLSLVLGLVCAQEPQPEQDLFELSGKWTTNYIGSSDLEKIGANAPFQ VFMRSIVFDDQESK V Y VDFFRKEN GICEEF SLSGTKLEGN T YDVD YV GDN R FVINYASETALILTNINVDEEGNKTVMTGLLGKGTDIEDLEIEKFKEVTRAN GIPEENIVNIIGRDDCPAK 71 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPF QVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEG NTYDVNYAGN NKFWSYASE TALIISNINVDEEGDKTIME GLLGK 72 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFWSYASETALITSNTNVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA 73 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETAIJISNrNVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAK 74 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDTEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK 75 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGGV CGPSPPCITT 76 EPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLN FFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFWSYASETALIISNINVDE EGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA 77 MKSLLI .SLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDI .EKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGN NKFVVSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEV TRENGIPEENIWIIERDDCPAK 78 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGN NKFVVSYASETALIISNINVDEEGDKTIMTGLLGKGTDTEDQDLEKFKEV TRENGIPEENIVNIIERDDCPAK 79 PFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSK ENG1CEEFSEIGTKQEGNTYDVNYAGNNKFWSYASETALIISNINVDEE GDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA 80 MKSLLLSLVLGLVCAQEPQPEQDPFEYFFLASGKWTTSYIGSSDLEKIGE NAPFQVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVN YAGNNKFWSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEK FKEVTRENGIPEENIVNIIERDDCPAK 81 MKSLLLSLVLGLVCAQEPQPEQDPFEVRGMGKWITSYIGSSDLEKIGENA PFQVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYA GNNKFWSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFK EVTRENGIPEENIVNUERDDCPAK 82 MKSLLLSLVLGLVCAQEPQPEQDLFELSGKWTTNYTGSSDLEKIGANAPFQ VFMRSTVFDDQESKVYVDFFRKENGTCEEFSLSGTKLEGNTYDVDYVGDNR FVINYASETALILTNINVDEEGNKTVMTGLLGKGTDIEDLEIEKFKEVTRAN GIPEENIVNIIGRDDCPAK Table 11. Non-Limiting Example Keratin / Keratin-Iike Peptide Sequences SEQ ID NO Sequences Keratin / Keratin-!ike peptides (KLPs) 90 MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFG SRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLL TPLNLEIDPNAQCVKQEEKEQTKSLNSRFAAFTDKVRFLEQQNKLLETKWQF YQNQRCCESNLEPLFSGYIETLRREAECVEANSGRLASELNHVQEVLEGYKK KYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLY EEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAES WYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLE AAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSK LGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGR QITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSSRSVRFA 91 GGVCGPSPPCITT 92 GGVCGPSPPC 93 CGPSPPCITT 94 CGPSPPC 95 GVCGPSPPC 96 CLPCLPAASC 97 CLPAASC 98 VSSCCKPQCC 99 CCKPQCC 100 CCQSSCCKPS 101 YGGSSGGG 102 FGGGS 103 CCQSSCCKPSC 104 CVSSCCKPQCC 105 PITCRRTCYH 106 DCKLPCNPCA 107 CLPCLPAASC 108 CEPA1CEPSC 109 CQCSCCKPYCS 110 FCGFPSCSTSC 111 CTPPSCCQLHHA 112 SCCAPVYCCK Table 12. Non-Limiting Example OBP (Fission Protein) Sequences SEQ ID NOS Sequences Each (XI) is independently absent or a linker peptide 201, QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL and 91 EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA(X DGGVCGPSPPCITT 202, 22 and 91 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVIALGGGNLEAITTFMREDRCIQKK1LMRKTEEPGKFSAYGGRKLIYL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHK GL.SEEDIFMPLQTGSCALL’PXI )GGVCGPSPPCI TT 203, 23 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRCIQKK1LMRKTEEPGKYSAYGGRKLMY and 91 LQELPRRDHYIFYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEH(X1)GGVCGPSPPCITT 204, 24 and 91 MAKFLLLALTFGLAHAAMEGPWKTVAIAADRVDKIERGGELRIYCRSLTCE KECKEMKVTFYVNEAGQCSLT'I'ITOTLQEDGKTYKTQFQGNNRYKIADES PENLTFYSEYVDRADRKTKLLFIEGllGPETSEQKEKFAELAEEKGIPAG VLITDYCPE(X1)GGVCGPSPPCITT 205, 25 MKSLLIAILLLGLVAVLKAQEAPPDDEVDYSGIWYAKAMVHNGTEPSHKIP SIVFPVRUAEEEGDLETTVVFWNYGHCREFKFVMKKTEEPGKYTAFEA'I'K and 91 V1HVEKTSVNEHY1FYCEGRHNGTSSFGA1GKLMGRDSGENPEAMEEFKNFI KRMNLRLENMFVPEIGDKCVESD(Xl 1GGVCGPSPPCITT 206, 26 MMVKFLLLALVFGLAHVHAHDHPELQGQ FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN and 91 NYKLLKATSENLVFYDENVDRASR.KTKLLYILGKGEALTHEQKERLTELAT QKGIPAGNLREI^HEDTCPE 207, 27 311(1 91 HHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN YNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQ DTCN Q(X 1)GGVCGPSPPCITT 208, 28 and 91 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN 'rh'l'lLKTDYDNYVMFHLYTNlVAfNGETFQLMELYGRTKDLSSDlKEKFAKLCV AHGURDN1IDLTKTDRCLQA(X1)GGVCGPSPPCITT 209, 29 and 91 MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKUFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDD1IFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYNIPNENTQHLVPTDTCNQ(X1)GGVCGPSPPC1TT 210, 410 and 91 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKWNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA HN1NVDKHGQTTELTGLFVKLNVEDEDLEKFWKLTEDKG1DKKNVVNFLE NEDHPHPE(X 1)GGVCGPSPPCITT 211, HKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY and 91 SDYVTLHlAYyVNGDKTFQLME^^ DLTKIDRCFQLRGSGGVQESSAE(X1)GGVCGPSPPCITT 212, 32 and 91 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN SSLLFNMHIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFRIVETDYTDY1 1FHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHG1VKEN1FDLTE VDRCLQARGSEKA(X1)GGVCGPSPPCUT 213, 411 and 91 MVKFLLLAFALSVSCAHHKIPEISPSEVDGKWRTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTLT1TFNTKEEGKCQTHTVVGRKDEDGQYKTGFSGNN DFHWEKADGIIIFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLEN1AKE FDISKENIQHLVPTDTCDQ(X 1 )GGVCGPSPPCITT 214, 34 and 91 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEK1GENAPFQV FMRS1EFDDKESKVYLNFFSKENG1CEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X1)GGVCGPSPPCITT 215, 35 MQILLLSLVLGVVCAVQEPQSETDYSlA'SGEWNTlYlGSSNrEKlSENGPFRrL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL and 91 HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE N1VN11N1DDCPTSE(X1)GGVCGPSPPCUT 216, 36 and 91 MQILLLALTIGLAYAHQTLDPSETNGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EYTGKKEDAIAFYNHNTDETGKETKMIVVVARRDSLTEEEQQKLQEVAGEK GIPKDNIRYFRERDTCAQ(X1)GGVCGPSPPCITT 217, 37 and 91 MKILLLCLILVLACDAHLPLPNVLTQVSGPWKTLYVSSNNLDKIAENGPFRI YIRRINVDIPRLK1LFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQ1 LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEEDIAKFKKLSREKGIP EENTIYLGDTDNCPNHE(X1)GGVCGPSPPCITT 218, 38 and 91 MKSLLLSLVLGLVCAQEPQPEQLWELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYIJNFFSKENGICEEFSLTGTKQEGNTYDWYAGNNKFVr VSYASETALriANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X)GGVCGPSPPCUT 219, 409 and 91 RSCV1HLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKV DVDVINGTVVFNFSVMMNGRCTEKSAVGT1GRDKFINIGSMNQNLFNLFSV TSNT1A1NVNTRRNTTKAFALLDTNGN1FN1GYDSLGSL11HTANVDTAGQTI QVFALLGKRI.HPDDNDFAKFRELMRENNrPEENLIDMSKTEKCPKKEKGTN PS(X1)GGVCGPSPPCITT 220, 40 and 91 MALLLLSLGLSL1TAQEFDPRNVMQRNYNMARVSGVWYS1FMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVVVVCEKTEKNGEYSI NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNll NLTNKDPCYSKHYRSPPRPPMRE(X1)GGVCGPSPPQTT 221, 21 and 92 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKT1MTGLLGKGTD1EDQDLEKFKEVTRENGIPEENIVNIIERDDCPA(X 1)GGVCGPSPPC 222, 22 and 92 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEH(X1)GGVCGPSPPC 223, 23 and 92 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMY LQELPRRDHY1FYCKDQHHGGL.LHMGKI.VGRNSDTNREALEEFKKI.VQRK GLSEEDIFTPLQTGSCVPEH(X1)GGVCGPSPPC 224, 412 and 92 M AKFLLLALTFGL AHA AMEGPWKTV AI A ADRVDKIERGGE LRIY CR SLICE KECKEMKVTFYVNENGQCSLTTITGYLQEDGKTYKTQFQGNNRYKLVDES PENLTFYSENVDRADRKTKLLEILGHGPLTSEQKEKFAELAEEKGIPAGNiRE VL1TDYCPE(X1)GGVCGPSPPC 225, 25 and 92 MKSLLLTILLLGLVAVLKAQEAPPDDLVDYSGIWYAKAMVHNGTLPSHKIP SIVFPVRnALEEGDLETTVVFWNNGHCREFKFVMKKTEEPGKYTAFHNTK VnTVEKTSVNEHYiFYCEGRHNGTSSFGMGKLMGRDSGENPEAMEEFKNFI KRMNLRLENMFV PEIGDK C VE SD(X 1 )GGV CGPSPPC 226, 26 and 92 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDENVDRASRKTKLLY1LGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPE(X1)GGVCGPSPPC 227, 27 and 92 HHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN VNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQ(X 1 )GGVCGPSPPC 228, 413 and 92 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFS1VVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN TFTILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSD1KEKFAKLCV AHGITRDNIIDLTKTDRCLQA(X1)GGVCGPSPPC 229, 29 MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR and 92 NYFHVLKKTDDIIFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYWPNENTQHLVPTDTCNQ(X1)GGVCGPSPPC 230, 410 and 92 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA HNINVDKHGQTTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVNFLE NEDHPHPE(X 1 )GGVCGPSPPC 231, 31 and 92 HKEAGQDWTSNFDASKIAGEWYS1LLASDAKENIEENGSMRVFVEHIRVL DN S SLAFKF QRK VN GEC TDF Y A V CDKV GDGV YTV AY Y GENKFRLLEVN Y SDYVlLHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVElCQQYGnKENn DLTKTDRCFQLRGSGGVQESSAE(X1)GGVCGPSPPC 232, 32 and 92 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN S SLLFN MH1KVDGKCTEIAL VSDKTEKDGE YS VE YDG YN VFR1VETD YTDYI IFHLVNFKEKDSFQMMELSAREPDTSEEVRKRF’VEYCQKHGIVKENIFDLTE VDRCLQARGSEKA(X1)GGVCGPSPPC 233 411’ and 92 MVKFLLLAFALSVSCAHHKIPEISPSEVDGKWTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTLTITFNTKEEGKCQTHTVVGRKDEDGQYKTGFSGNN DFHVVEKADG11IFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLEN1AKE FDISKENIQHLVPTDTCDQ(X1)GGVCGPSPPC 234, 34 and 92 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VS Y ASET ALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X1)GGVCGPSPPC 235. 35 and 92 MQTLLLSLVLGWCAVQEPQSETDYSLFSGEWNTIYIGSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE NrVNirNIDDCPTSE(X 1 )GGVCGPS PPG 236, 36 and 92 MQILLLALTIGLAYAHQTLDPSE1NGQWHT1S1AADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EV1GKKEDA1AFYNHNTDETGKETKM1VVVARRDSLTEEEQQKLQEVAGEK G1PKDNIR YFRERDTCAQ(X 1 )GGVCGPSPPC 237, 37 and 92 MKILLLCL1LVLACDAHLPLPNVLTQVSGPWKTLYVSSNNLDKIAENGPFRI Y1RRINVDIPRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEED1AKFKKLSREKG1P EEN1IYLGDTDNCPNHE(X1)GGVCGPSPPC 238, 38 and 92 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSTEFDDKESKVYLNFFSKENGTCEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X1)GGVCGPSPPC RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKV 239, 409 and 92 240, DVDVTNGTVVFNFSVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSV TSNTIAINVNTRRNTTKAFALLDTNGNIFNIGYDSLGSLIIHTANVDTAGQTT QVFALLGKRLHPDDNDFAKFRELMRENNIPEENLIDMSKTEKCTKKEKGTN PS(X1)GGVCGPSPPC MALLLLSLGLSLITAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK 40 and 92 ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVWVCEKTEKNGEYS1 NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII NL1WDPCYSKHYRSPPRPPMRE(X1)GGVCGPSPPC 241, 21 and 93 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFWSYASETALITSNTNVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAIX 1)CGPSPPCITT 242, 22 and 93 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEH(X1)CGPSPPCITT 243, MKTLFLGVTLGIAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS and 93 a V lx V .1 r’xJi.A.j l_j kjIx. iLjA-'.rt. I i a 1 iviix.ix. I.L.IVaaVj.x. 1 a.<j.ja kj.ix i Cj / j. i              j.jj.v.i LQELPRRDHYIFYCK.DQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEH(X1)CGPSPPCITT 244, 412 and 93 PENL.TFYSENVDRADRKTKLUn,GHGPLTSEQKEKFAELAEEKGIPAGNIRE VUTDYCPE(X1)CGPSPPC1TT 245, 25 SIVFPVRnALEEGDLETTVVFWNNGHCREFKFVMKKTEEPGKYTAFHNTK and 93 KREFN LRLENMFVPEIGDKCVESD(X1)CGPSPPCITT    ! * 246, 26 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN and 93 NYKLLKATSENLVFYDENVDRASRKTKLLYILGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPE(X1)CGPSPPCITT 247, 2 7 and 93 HHENLDISPSEVNGDWR.TLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN VNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQ(X1)CGPSPPCITT 248, MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGS 413 and 93 MRVFVQHIDVLENSLGFTFRIK.ENGVCTEFSLVADKTAKDGEYFVEYDGEN TFTILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSDIKEKFAKLCV AHGITRDNni.>L^^^^ 249, 29 and 93 250, MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKI1FNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDIIFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYNIPNENTQHLVPTDTCNQ(X1)CGPSPPCITT AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV 410 DFYFSVKRDGKVVKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA and 93 HNINVDKHGQTTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVNFLE NEDHPHPE(X DCGPSPPCITT 251, 31 and 93 HKEAGQDWTSNFDASKIAGEWSILLASDAKENIEENGSMRVFVEHIRVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY SDYVILHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVEICGQYGH^ DLTK1DRCFQLRGSGGVQESSAE(X1)CGPSPPCITT 252, 32 and 93 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN SSLLFNMHIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFRIVETDYTDYI IFHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHGIVKENIFDLTE VDRCLQARGSEKA(X1)CGPSPPCITT 253, 411 and 93 MVKFUAAFALSVSCAHHKIPEISPSEVre AYFRHMECSDECQTLTTTFNTKEEGKCQTHTWGRKDEDGQYKTGFSGNN DFHVVEKADGIIIFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLENIAKE FDISKENIQHLVPTDTCDQ(X1)CGPSPPCITT 254, 34 and 93 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X1)CGPSPPCITT 255, 35 and 93 MQ1LLLSLVLGVVCAVQEPQSETDYSLFSGEWNTIYIGSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE NIVN1INIDDCPTSE(X1)CGPSPPC1TT 256, 36 and 93 MQTLLLALTIGLAYAHQTLDPSEINGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EVIGKKEDAIAFYNHNTDETGKETKMIVWARRDSLTEEEQQKLQEVAGEK GIPKDNIRYFRERDTCAQ(X1)CGPSPPCITT 257, 37 and 93 MK.TLLLCLILVLACDAHLPLPNVLTQVSGPWKTLWSSNNLDKIAENGPFRI YIRRTNVDIPRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEEDIAKFKKLSREKGIP EENIIYLGDTDNCPNHE(X1)CGPSPPCITT 258, 38 and 93 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNnERDDCPAK(Xl )CGPSPPCITT 259, 409 and 93 RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGY1CKV DVDVTNGTVVFNFSVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSV TSNTIAINVNTRRNTTKAFALLDTNGNIFNIGYDSLGSLIIHTANVDTAGQTT QVFALLGKRL.HPDDNDFAKFRELMRENNIPEENL1DMSKTEKCPKKEKGTN PS(X1)CGPSPPCIT T 260, 40 and 93 MALLLLSLGLSLITAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVWVCEKTEKNGEYSl NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII NLTNKDPCYSKHYRSPPRI’PMRECXljCGPSPPClTT 261, 21 and 94 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEG-NTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAIX DCGPSPPC 2.62, 22 and 94 MKTLELGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKL1YL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNl'NLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEH(X1)CGPSPPC 263, 23 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMY and 94 LQELPRRDHYIFYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEH(X1)CGPSPPC 264, 412 and 94 MAKFLLLALTFGLAHAAMEGPWKTVAIAADRVDKIERGGELRIYCRSLTCE KECKEMKVTFYVNENGQCSLTTITGYLQEDGKTYKTQFQGNNRYKLVDES PENLTFYSEXVDRADRKTKLLFILGHGPLTSEQKEKFAELAEEKGlPAGNilRE V L1TDYCPE(X 1 )CGPSPPC 265, 25 and 94 MKSLLLTILLLGLVAVLKAQEAPPDDLVDYS SIVFPVRnALEEGDEETTVVFWNNGHCREFKFVMKKTEEPGO VIHVEKTSYNEHYTFYCEGRHNGTSSFGMGKLMGRDSGENPEAMEEF^ KRMNLRLENMFVPEIGDKCVESD(Xl 1CGPSPPC 266, 26 and 94 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTA1MADN1DK1ETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDENVDRASRKTKLEY1LGKGEALTHEQKERLTELAT QK.GIPAGNLRELAHEDTCPE(X1)CGPSPPC 267, 27 and 94 HHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN VWDESGKETWILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQ(X1)CGPSPPC 268, 413 and 94 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFS1VVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN TFTILKTDYDNYVMFHLYTnIVTnNGETFQLMELYGRTKDLSSDIKEKFAKLCV AHGITRDNIIDLTKTDRCLQA(X1)CGPSPPC 269, 29 and 94 MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKUFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDIIFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EE YN1PNENTQHLVPTDTCNQ(X1 )CGPSPPC 270 410 and 94 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQ HNINVDKHGQTTEIYIGUFV^ NEDHPHPE(X1)CGPSPPC 271, 31 and 94 HKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY SDYV1LHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVE1CQQYG1IKEN11 DLTK1DRCFQLRGSGG VQE S S AE( X1 )CGPSPPC 272, 32 and 94 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN SSLLFNMHIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFRIVETDYTDY1 IFHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHGIVKEN1FDLTE VDRCLQARGSEKA(X 1 )CGP SPPC 273, 411 and 94 MVKFLLLAFALSVSCAHHKIPEISPSEVDGKWRTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTLT1TFNTKEEGKCQTHTVVGRKDEDGQYKTGFSGNN DFHWEKADGIIIFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLEN1AKE FDISKENIQHLVPTDTCDQ(X1)CGPSPPC 274, 34 and 94 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEK1GENAPFQV FMRS1EFDDKESKVYLNFFSKENG1CEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKT1MTGLLGKGTD1EDQDLEKFKEVTRENG1P EENrVNlIERDDCPAK(Xl)CGPSPPC 275, 35 and 94 MQILLLSLVLGVVCAVQEPQSETDYSLFSGEWNT1Y1GSSNIEKISENGPFRIL LRRLDLDSAGDR1IYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE NIVNIIN1DDCPTSE(X1)CGPSPPC 276, 36 and 94 MQILLLALTIGLAYAHQTLDPSETNGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EVIGKKEDAIAFYNHNTDETGKETKMIVWARRDSLTEEEQQKLQEVAGEK GIPKDNIRYFRERDTCAQ(X 1 )CGPSPPC 277, 37 and 94 MKILLLCLILVLACDAHLPLPNVI. / rQVSGPWKTLYVSSNNLDKIAENGPFRI YTRRINVDIPRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHV'NEEDIAKFKKLSREKGIP EENII YLGDTDNCPNHE(X1 )CGPSPPC 278, 38 and 94 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASEIALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X 1 )CGPSPPC 279, 409 and 94 280, 40 and 94 RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNILLVAATNVDKISNGPFHGYICKV DVDVTNGTVVFNFSVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSV TSNT1A1NVNTRRNTTKAFALLDTNGNIFNIGYDSLGSL1IHTANVDTAGQTT QVF ALLGKRLHPDDNDF AKFRELMRENNIPEEN LIDMSKTEKCPKKEKGTN PS(X1)CGPSPPC MALLLLSLGLSL1TAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVVVVCEKTEKNGEYSI NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII NLTNKDPCYSKHYRSPPRPPMRE(X1)CGPSPPC 281, 21 and 95 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYT NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPA(X 1)GVCGPSPPC 282, 22 and 95 MKTLFLGVTLGLAAALSFTLEEEDITGTWWKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEH(X1)GVCGPSPPC 283, 23 and 95 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFIFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMY LQELPRRDHYIFYCKDQHHGGLLHMGK.LVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEH(X1)GVCGPSPPC 284, 412 and 95 M AKFLLLALTFGF AHA AMEGPWKTV AI A ADRVDKIERGGE LRi Y CRSLTCE KECKEMKVTFYVNENGQCSL / FnTGYLQEDGKTYKTQFQGNNRYKLVDES PENLTFYSENVDRADRKTKLLFILGHGPLTSEQKEKFAELAEEKGIPAGNIRB VL1TDYCPE(X1)GVCGPSPPC 285, 25 MKSLLLTILLLGLVAVLKAQEAPPDDLVDYSGIWYAKAM.VHNGTLPSHKIP SIVFPVRIIALEEGDLETTVVFWNNGIKAEFKFV^^ and 95 V1HVEKTSV N EHY1FYCEGRHNGTSSFGMGKLMGRDSGEN PEAMEEFKNF1 KRM14LRLENMFVPE1GDKCVESD(X1)GVCGPSPPC 286, 26 and 95 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDEWDRASRKTKLLYILGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPE(X1)GVCGPSPPC 287, 2 7 and 95 HHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN VNVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQ(X 1 )GVCGPSPPC 288, 413 and 95 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFSIVVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN TFTILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSDIKEKFAKLCV AHGITRDNnDLT^ 289, 29 and 95 MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKI1FNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDIIFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYNIPNENTQHLVPTDTCNQ(X1)GVCGPSPPC 290, 410 and 95 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA HN1NVDKHGQTTEL TGLFVKLNVEDEDLEKFVVKLTEDKG1DKKNVVNFLE NEDHPHPE(X1)GVCGPSPPC 291, 31 and 95 HKEAGQDWTSNFDASKIAGEWYSTLLASDAKENIEENGSMRVFVEHIRVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY SDYVILHLVDWGDKTFQLMEFYGRKPDVEPKLKDKFVEICQQYGIIKENII DLTKIDRCFQLRGSGGVQESSAE(X1)GVCGPSPPC 292, 32 and 95 HEJIGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRW^ SSLLFNWIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFR1VETDYTDYI 1FHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHGIVKENIFDLTE VDRCLQARGSEKA(X1)GVCGPSPPC 293, 411 and 95 MVKFLLLAFALSVSCAHHKIPEISPSEVDGKWRTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTL / TTTFNTKEEGKCQTHTVVGRKDEDGQYKTGFSGNN DFHVVEKADGIIIFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLENIAKE FD1SKENIQHLVPTDTCDQ(X1)GVCGPSPPC 294, 34 and 95 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEK1GENAPFQV FMRS1EFDDKESKVYLNFFSKENG1CEEFSL1GTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKT1MTGLLGKGTD1EDQDLEKFKEVTRENG1P EEN1VNUERDDCPAK(X1)GVCGPSPPC 295, 35 and 95 MQILLLSLVLGVVCAVQEPQSETDYSLFSGEWNT1Y1GSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE N1VN1IMDDCPTSE(X1)GVCGPSPPC 296, 36 and 95 MQILLLALTIGLAYAHQTLDPSE1NGQWHT1S1AADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EV1GKKEDAIAFYNHNTDETGKETKMIVWARRDSLTEEEQQKLQEVAGEK G1PKDNIRYFRERDTCAQ(X 1 )GVCGPSPPC 297, 37 MKILLLCIJLVLACDAHLPLPNVL / rQVSGPWKTLYVSSNNLDKIAENGPFRl YTRRINVDIPRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI and 95 LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEEDIAKFKKLSREKGIP EEN1IYLGDTDNCPNHE(X1)GVCGPSPPC 298, 38 and 95 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVF MRSTEFDDKESKVYLNFFSKENGTCEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVN1IERDDCPAK(X1)GVCGPSPPC 299, 409 and 95 RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKV DVDVTNGTWFNFSVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSV TSNTIA1NVNTRRNTTKAFALLDTNGNIFNIGYDSLGSLIIHTANVDTAGQTT QVFALLGKRLHPDDNDFAKFRELMRENNIPEENLIDMSKTEKCPKKEKGTN PS(X1)GVCGPSPPC 300, 40 and 95 MAU idSi AH .SIJTAQEFDPRNVMQRNYNMARVSGVWYSIFMADDI XRIK ENGDLRVFVQNIEHLKNGSLKFDFEYWQGECVAVVTVCEKTEKNGEYSI NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII NLTNKDPCYSKHYR.SPPRPPMRE(X 1 )GVCGPSPPC 301 and 43 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFWSYASETALIISNINVD EEGDK.TIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIWIIERDDCPA(X 1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 302 and 22 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATF1TMREDRCIQKKILMRKTEEPGKFSAYGGRKL1YL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEH(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 303 and 23 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMY LQELPRRDHYIFYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEH(XI)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 304 and 412 VLITDYCPE(XI)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 305 and 25 SIVFPVRnALEEGDLETTVVFWNNGHCREFKFVMKKTEEPGKYTAFHNTK KRMNLRLENMFVPE1GDKCVESD(XI)(X2), wherein X2 is any one of SEQ ID NOS: 91-112                                                ’ 306 and 26 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNTDKTETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDENVDRASRKTKLLYTLGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPE(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112                                   '                                  ' 307 and 27 HHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN VNVDESGKETNV1LVAGKREDLNKAQKQELRKLAEEYN1PNENTQHLVPT DTCXQl X U X2 k wherein X2 is any one of SEQ ID NOS: 91-112 308 and 413 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFS1VVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN IM’ILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSDIKEKFAKLCV AHGITRDNIIDLTKTDRCLQA(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 309 and 29 MVKFLLIVLALGVSCAHHENLDISPSEWGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDIIFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYNIPNENTQHLVPTDTCNQ(X1)('X2), wherein X2 is any one of SEQ ID NOS: 91-112 310 and 410 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKWKNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA HNINVDKHGQTTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVNFLE NEDHPHPE(XI)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 311 and 31 HKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVL DNSSLAFKFQRKVNGECTDFYAVCDKVGDGVYTVAYYGENKFRLLEVNY SDYVILHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVEICQQYGIIKENII DLTKTDRCFQLRGSGGVQESSAE(X1)(X2). wherein X2 is any one of SEQ ID NOS: 91-112                                           ' 312 and 32 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHrEVLSN S SLLFNMHIK VDGKCTEIALV SDKTEKDGE YS VE YDGYNVFRIVETD YTDYI IFHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHGIVKENIFDLTE VDRCLQARGSEKA(X 1 )(X2), wherein X2 is any one of SEQ ID NOS: 91-112 313 and 411 MVKFLLLAFALSVSCAHHK1PEISPSEVDGKWRTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTLT1TFNTKEEGKCQTHTWGRKDEDGQYKTGFSGNN DFHVVEKADGIIIFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERL.EN1AKE FD1SKENIQHLVPTDTCDQ(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91112 314 and 34 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 315 and 35 MQTLLLSLVLGVVCAVQEPQSETDYSLFSGEWNTIYIGSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE NIVNIINIDDCPTSE(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 316 and 36 MQTLLLALTIGLAYAHQTLDPSEINGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EVIGKKEDAIAFYNHNTDETGKETKMIVWARRDSLTEEEQQKLQEVAGEK GIPKDNIRYFRERDTCAQ(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91112 317 and 37 MKILLLCLILVLACDAHLPLPNVL / fQVSGPWKTLYVSSNNLDKIAENGPFRI YTRRINVDIPRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEEDIAKFKKLSREKGIP EENIIYLGDTDNCPNHE(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 318 and 38 MKSLLLSLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDLEK1GENAPFQVF MRSIEFDDKESKVYLNFFSKENGICEEFSLTGTKQEGNTYDVNYAGNNKFV VSYASEIAL1IANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAK(X1)(X2). wherein X2 is any one of SEQ ID NOS: 91-112 319 and 409 RSCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKV DVDV1NGTVVFNFSVMMNGRCTEKSAVGITGRDKFINIGSMNQNLFNLFSV TSNTIAINVNTRRNTTKAFALLDTNGNIFNIGYDSLGSIJIHTANVDTAGQTT QVFALLGKRLHPDDNDFAKFRELMRENNIPEENL1DMSKTEKCPKKEKGTN PS(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112 320 and 40 MALLLLSLGLSLITAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVWVCEKTEKNGEYSI NYEGQNTVAVSETDYRLF1TFHLQNFRNGTETHTLALYETCKKYGLGSQNII NLTNKDPCYSKHYRSPPRPPMRE(X1)(X2), wherein X2 is any one of SEQ ID NOS: 91-112                                             ' 321 QEPQPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYL NFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFVVSYASETALIISNINVD EEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAGQ GQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GGVCGPSPPCITT 322 MKTLFLGVTLGLAAALSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVS PVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYL QELPGTDDYVFYCKDQRRGGLRYMGKLVGRNPNTNLEALEEFKKLVQHK GLSEEDIFMPLQTGSCVLEHGQGQGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQGQGQ GGVCGPSPPCITT 323 MKTLFLGVTLGLAAALSFTLEEEDITGTWYV'KAMVVDKDFPEDRRPRKVS PVKVTALGGGKLEATFTFMREDRCIQKKILMRKTEEPGKYSAYGGRKLMY LQELPRRDHYIFYCKDQHHGGLLHMGKLVGRNSDTNREALEEFKKLVQRK GLSEEDIFTPLQTGSCVPEHGQGQGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQGQGQ GGVCGPSPPCITT 324 KECKEMKVTFYVNENGQCSLTTITGYL.QEDGKTYKTQFQGNNRYKL.VDES VLs IDY CPeGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQG Q GGVCGPSPPCITT '                  '                     ' 325 MKSLLLTILLLGLVAVLKAQEAPPDDLVDYSGIWYAKAMVHNGTLPSHKIP KRMNLRLENMFVPEIGDKCVESDGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQGQGQGQGQ GGVCGPSPPCITT 326 MMVKFLLLALVFGLAHVHAHDHPELQGQWKTTAIMADNIDKIETSGPLEL FVREITCDEGCQKMKVTFYVKQNGQCSLTTVTGYKQEDGKTFKNQYEGEN NYKLLKATSENLVFYDENVDRASRKTKLLYILGKGEALTHEQKERLTELAT QKGIPAGNLRELAHEDTCPEGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GQGQGQGQGQGQ GGVCGPSPPCITT 327 HHENLDISPSEVTSGDWRTLYIVADNVEKVAEGGSLRAYFQHMECGDECQE LK1IFNVKLDSECQTHTVVGQKHEDGRYTTDYSGRNYFHVLKKTDDIIFFHN V'NVDESGKETNVILVAGKREDLNKAQKQELRKLAEEYNIPNENTQHLVPT DTCNQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GGVCGPSPPCITT 328 MRGSHHHHHHTDPEEASFERGNLDVDKLNGDWFSTVVASDKREKIEENGS MRVFVQHIDVLENSLGFTFRIKENGVCTEFSLVADKTAKDGEYFVEYDGEN TFTILKTDYDNYVMFHLVNVNNGETFQLMELYGRTKDLSSDIKEKFAKLCV AHGITRDNIIDLTKTDRCLQAGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GQGQGQGQGQGQ GGVCGP SPPCITT 329 MVKFLLIVLALGVSCAHHENLDISPSEVNGDWRTLYIVADNVEKVAEGGSL RAYFQHMECGDECQELKIIFNVKLDSECQTHTVVGQKHEDGRYTTDYSGR NYFHVLKKTDDIIFFHNVNVDESGRRQCDLVAGKREDLNKAQKQELRKLA EEYNIPNENTQHLVPTDTCNQGQGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQGQGQGQ GGVCGPSPPCITT 330 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTV DFYFSVKRDGKWNVHVKATKQDDGTYVADYEGQNVFKIVSLSRTHLVA HNINVDKHGQTTELTGLFVKLNVEDEDLEKFWKLTEDKGIDKKNVVNFLE NEDHPHPEGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQG Q GGVCGPSPPCITT 331 HKEAGQDVVTSNFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVL DN S SLA FKF QRK VN GEC TDF Y A VCDKV GDGV YTV A Y YGENKFRLLEVN Y SDYVILHLVDVNGDKTFQLMEFYGRKPDVEPKLKDKFVEICQQYGIIKENIT DLTKIDRCFQLRGSGGVQESSAEGQGQGQGQGQGQGQGQGQGQGQGQGQ GQGQGQGQGQGQGQ GGVCGPSPPCITT 332 HEEGNDVRRNFDVSKISGYWYSVLLASDVREKTEENSSMRVFVNHIEVLSN SSLLFNMHIKVDGKCTEIALVSDKTEKDGEYSVEYDGYNVFRIVETDYTDY1 TFHLVNFKEKDSFQMMELSAREPDTSEEVRKRFVEYCQKHGIVKENIFDLTE VDRCLQARGSEKAGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GQGQGQ GQGQGQ GGVCGPSPPCITT 333 MVKFLLLAFALSVSCAHHKIPEISPSEVDGKWRTLYIGADNTEKVIQGGPLR AYFRHMECSDECQTLTITFNTKEEGKCQTHTVVGRKDEDGQYKTGFSGNN DFHVVEKADGI1IFHNVNVDSSGKKTNVILVAGKGKSLSKEQKERLENIAKE FDISKENIQHLVPTDTCDQGQGQGQGQGQGQGQ GQGQGQ GQGQGQGQGQ GQGQGQGQGQ GGVCGPSPPCITT 334 MKSLLLSLVLGLVCAQEPQPEQDPFVLSGKWITSYIGSSDLEKIGENAPFQV FMRSIEFDDKESKVYLNFFSKENGICEEFSLIGTKQEGNTYDVNYAGNNKFV VSYASETALIISNINVDEEGDKTIMTGLLGKG TDIEDQDLEKFKEVTRENGIPEENIVNIIERDDCPAKGQGQGQGQGQGQGQ GQGQGQGQGQGQGQGQGQGQGQGQGQ GGVCGPSPPCITT 335 MQ1LLLSLVLGVVCAVQEPQSETDYSLFSGEWNTIYIGSSNIEKISENGPFRIL LRRLDLDSAGDRIIYTFFLKVNGQCTKISSLAIKTEENTYVCHYAGKNKFEIL HLSKTAIIIDIVNEDEGGLVTKMVALVGMLGDIQKEDIEKFKEVAKEKEIPEE NIVNIINIDDCPTSEGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GQGQGQ GGVCGPSPPCITT 336 MQILLLALTIGLAYAHQTLDPSEINGQWHTISIAADNVEKIGEGGPLRGYFH NLHCYDGCKNIGLTFYVKLDGNCQRFDVLGAKQEDSDVYVAQYSGTNHF EVIGKKEDAIAFYNHNTDETGKETKMIVVVARRDSLTEEEQQKLQEVAGEK GIPKDNTRYFRERDTCAQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GQGQGQGQGQ GGVCGPSPPCITT 337 MK.TLLLCLILVLACDAHLPLPNVLTQVSGPWKTLWSSNNLDKIAENGPFRI YIRRINVDIPRLKILFSFFVKVDGECVEKSVEASIGQDNLINAHYAGGNYHQI LDVTPNALIGYIVNVDDKGRITKLASLVGRGAHVNEEDIAKFKKLSREKGIP EENIIYLGDTDNCPNHEGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQGQ GGVCGPSPPCITT 338 MKSL / LIXLVLGLVCAQEPQPEQDPFELSGKWITSYIGSSDIXKIGENAPFQVF MRSIEFDDKESKVYLNFFSKENGICFXFSLTGTKQEGNTYDVNYAGNNKFV VSYASETALIIANINVDEEGDKTIMTGLLGKGTDIEDQDLEKFKEVTRENGIP EENIVNIIERDDCPAKGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQ GGVCGPSPPCITT 339 R.SCVIHLQCLPTGCLFSALHNGLPDGRLPLPDGRLPLPDGRLPLPDSRLPLPD GRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLPLPDGRLP LPEGRLPLPDSHPPLQDNLTQLSGEWNTLLVAATNVDKISNGPFHGYICKV DVDVTNGTWFNFSVMMNGRCTEKSAVGTIGRDKFINIGSMNQNLFNLFSV TSNTIAiNVNTRRNTTKAFALLDTNGNIFNIGYDSLGSLIIHTANVDTAGQTT QVFALLGKRLHPDDNDFAKFRELMRENNIPEENLIDMSKTEKCPKKEKGTN PSGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQGQ GGVCGPSPPCITT 340 MALLLLSLGLSLITAQEFDPRNVMQRNYNMARVSGVWYSIFMADDLNRIK ENGDLRVFVQNIEHLKNGSLKFDFEYMVQGECVAVWVCEKTEKNGEYSI NYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCKKYGLGSQNII NLTNKDPCYSKHYRSPPRPPMREGQGQGQGQGQGQGQGQGQGQGQGQG QGQGQGQGQGQGQGQ GGVCGPSPPCITT Table 13. Non-Limiting Example Linker Sequences SEQ ID NO Sequences 401 GQG QGQGQGQGQG QGQGQGQGQG QGQGQGQGQG QGQGQGQ 402 AKAKAKAKAKAKAKAKAKAKAKAKAKAKAK 403 LKLKLKLKLKLKLKLKLKLKLKLKLKLKLK 404 GAGAGAGAGAGAGAGAGAGAGAGAGAGAGA LA SEQ ID NO: 405 (GQ)n, where n is 1-20 LB SEQ ID NO: 406 (AK)n, where n is 1-20 LC SEQ ID NO: 407 (LK)n, where n is 1-20 LD SEQ ID \O 408 (GA)n, where n is 1-20

[0108] In certain embodiments, about 0.001% to about 1% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In some embodiments, about 0.0025% to about 0.5% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In certain embodiments, about 0.005% to about ¢). 1% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In specific embodiments, about 0.009% to about 0.011% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In still more specific embodiments, about 0.01% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In yet more specific embodiments, about 0.05% to about 0.07% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In specific embodiments, an odor binding protein in a composition (e.g., a composition provided herein) comprises e.g., a sequence at least about 80% identical to any one of SEQ ID NOS: 1-82, 201-340.

[0109] In some embodiments, a composition provided herein comprises an odor binding protein (e.g., an odor binding protein provided herein) at about 0.001% to about 1% (w / w) of die composition. In some embodiments, about 0,001% to about 0.002%, about 0.001% to about 0.004%, about 0.001% to about 0.006%, about 0.001% to about 0.008%, about 0.001% to about 0.01%, about 0.001% to about 0.015%, about 0.001% to about 0.05%, about 0.001% to about 0.1%, about 0.001% to about 0.2.5%, about 0.001% to about 0.5%, about 0.001% to about 1%, about 0.002% to about 0.004%, about 0.002% to about 0.006%, about 0.002% to about 0.008%, about 0.002% to about 0.01%, about 0.002% to about 0.015%, about 0.002% to about 0.05%, about 0.002% to about 0.1%, about 0.002% to about 0.25%, about 0.002% to about 0.5%, about 0.002% to about 1%, about 0.004% to about 0.006%, about 0.004% to about 0.008%, about 0.004% to about 0.01%, about 0.004% to about 0.015%, about 0.004% to about 0.05%, about 0.004% to about 0.1%, about 0.004% to about 0.25%, about 0.004% to about 0.5%, about 0.004% to about 1%, about 0.006% to about 0.008%, about 0.006% to about 0.01%, about 0.006% to about 0.015%, about 0.006% to about 0.05%, about 0.006% to about 0.1%, about 0.006% to about 0.25%, about 0.006% to about 0.5%, about 0.006% to about 1%, about 0.008% to about 0.01%, about 0.008% to about 0.015%, about 0.008% to about 0.05%, about 0.008% to about 0.1%, about 0.008% to about 0.25%, about 0.008% to about 0.5%, about 0.008% to about 1%, about 0.01% to about 0.015%, about 0,01% to about 0.05%, about 0.01% to about 0.1%, about 0.01% to about 0.25%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.015% to about 0.05%, about 0.015% to about 0.1%, about 0.015% to about 0.25%, about 0.015% to about 0.5%, about 0.015% to about 1%, about 0.05% to about 0.1%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.1% to about 0.25%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.25% to about 0.5%, about 0.25% to about 1%, or about 0.5% to about 1% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In some embodiments, about 0.001%, about 0.002%, about 0.004%, about 0.006%, about 0.008%, about 0.01%, about 0.015%, about 0.05%, about 0.1%, about 0.2.5%, about 0.5%, or about 1% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In some embodiments, at least about 0.001%, about 0.002%, about 0.004%, about 0.006%, about 0.008%, about 0.01%, about 0.015%, about 0.05%, about 0.1%, about 0.25%, or about 0.5% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In some embodiments, not more than about 0.002%, about 0.004%, about 0.006%, about 0.008%, about 0.01%, about 0.015%, about 0.05%, about 0.1%, about 0.25%, about 0.5%, or about 1% (w / w) of a composition provided herein is an odor binding protein (e.g., an odor binding protein provided herein). In some embodiments, the composition comprising an odor binding protein maintains or increases a hair property to where applied, e.g., hair and / or skin of individuals, as compared to the hair property' of hair not applied with the composition. In some embodiments, the composition comprising an odor binding protein increases a hair property to where applied, e.g., hair and / or skin of individuals, when compared to no application of the composition. In some embodiments, the composition comprising an odor binding protein increases a hair property to where applied, e.g., hair and / or skin of individuals, when compared to a baseline measurement. In some embodiments, the composition comprising an odor binding protein maintains a hair property to where applied, e.g., hair and / or skin of individuals, when compared to no application of the composition. In some embodiments, the composition comprising an odor binding protein maintains a hair property to where applied, e.g., hair and / or skin of individuals, when compared to a baseline measurement. In some embodiments, the composition comprising an odor binding protein is applied to hair prior to heat application.

[0110] In some aspects, compositions (e.g., a composition provided herein) comprise an absorbing agent. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise an absorbing agent (such as oil absorbing agents). In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one absorbing agent, two absorbing agents, three absorbing agents, four absorbing agents, five absorbing agents, or more. In certain embodiments, an absorbing agent (e.g., an absorbing agent provided herein) is added to a composition (e.g., a composition provided herein, such as a non-aerosol formulation). In certain instances, absorbing agents are useful tor reducing excess oils (e.g., on the scalp or hair of an individual) and are added to compositions (e.g., a non-aerosol formulation) provided herein for such purpose. In certain instances, absorbing agents are oil absorbing agents. In some instances, properties of the absorbing agents, such as multiporous structure allows for absorption of oils and sebum (e.g., on the scalp and hair of an individual). In certain instances, tire shape and structure of particles of absorbing agents absorb sweat and oils (e.g., from the skin of an individual). In some embodiments, the absorbing agent may physically absorb sebum and / or oil. In some embodiments, the absorbing agent my chemically absorb sebum and / or oil (e.g., by forming a covalent bond with the sebum and / or oil, interacting with the sebum and / or oil via intermolecular forces, such as ionic interactions, van der Waals interactions, and the like). [Gill] In some embodiments, an absorbing agent (e.g., an absorbing agent provided herein) comprises a compound comprising silicon (e.g., silica, silica silylate), silica derivatives, synthetic silica derivatives, silicate salts, carbonate salts, metal oxides, clay mineral powders (e.g., talc), and / or any combination of one or more thereof. In specific embodiments, the absorbing agent comprises a compound comprising silicon. In yet more specific embodiments, the absorbing agents comprises a compound comprising silicon, wherein the compound comprises silica, silica silylate, silica dimethyl silylate, silica dimethicone silylate, and / or the like. In certain embodiments, the absorbing agent comprises silica, spherical silica, fumed silica, precipitated silica, silicone-surface treated silica, hydroxyapatite, talc, mica, silica, magnesium silicate, synthetic fluorophlogopite, calcium silicate, aluminum silicate, bentonite, montmorillonite, silica silylate, silica dimethyl silylate, silica dimethicone silylate, starch, distarch phosphate, tapioca starch, oryza sativa (rice) starch, solanum tuberosum (potato) starch, zea mays (com) starch, hydrolyzed corn starch, potato starch modified, corn starch modified, sodium polyacrylate starch, sodium carboxymethyl starch, calcium starch octenylsuccinate, sodium starch octenylsuccinate, aluminum starch octenylsuccinate, hydrolyzed com starch octenylsuccinate, sodium hydroxypropyl oxidized starch succinate, hydrolyzed corn starch hydroxyethyl ether, hydroxypropyl starch phosphate, sodium hydroxypropyl starch phosphate, hydroxypropyl oxidized starch pg-trimonium chloride, starch hydroxypropylfrimomum chloride, dimethylimidazolidinone rice starch, nylon-12, methyl methacrylate crosspolymer (MMA), polymethylmethacrylate (PMMA), HDI / trimethyloI hexyllactone crosspolymer, dimethicone / vinyl dimethicone crosspolymer, divinyldimethicone / dimethicone crosspolymer, dimethicone crosspolymer, poly silicone-11, polymethylsilsesquioxane (PSQ), polymethylsilsesquioxane / trimethylsiloxysilicate, divmyldimethicone / dimethicone / phenylsilsesquioxane crosspolymer, polydimethylsiloxane, lauroyl lysine, talc, boron nitride, bismuth oxychloride, alumina, magnesium aluminum silicate, kaolin, montmorillonite, bentonite, hectorite, illite, perlite, calcite, clay, Canadian colloidal clay, Moroccan lava clay, hydroxyapatite, disteardimonium hectorite, stearalkonium hectorite, quatemium-90 sepiolite, quatemium-90 montmorillonite, quatemium-18 bentonite, calcium carbonate, magnesium carbonate, silt, sea silt, mica, synthetic fluorphlogopite, calcium silicate, magnesium aluminum silicate, sodium potassium aluminum silicate, calcium sodium borosilicate, calcium aluminum borosilicate, nephrite powder, titanium dioxide, tin oxide, synthetic sapphire, carbon, charcoal, iron oxides, dextrin, maltodextrin, hydroxypropyltrimonium maltodextrin crosspolymer, inulin, cellulose, cellulose acetate, cellulose gum, microcrystalline cellulose, hydroxyethylcellulose, hydroxymethylcellulose, hydroxypropyl methylcellulose, diatomaceous earth, olea europaea (olive) seed powder, zea mays (corn) bran extract, maranta arundinacea root extract (arrowroot starch), hordeum vulgare (barley) seed flour, or a combination of two or more thereof.

[0112] In specific embodiments, an absorbing agent in a composition (e.g., a composition provided herein) comprises hydroxyapatite. In yet more specific embodiments, an absorbing agent in a composition (e.g., a composition provided herein) comprises silica. In still more specific embodiments, an absorbing agent in a composition (e.g., a composition provided herein) comprises magnesium silicate.

[0113] In certain embodiments, a composition (e.g., a composition provided herein) comprises an absorbing agent (e.g., an absorbing agent provided herein). In certain embodiments, about 0.01% to about 40% (w / w) of a composition provided herein is an absorbing agent (e.g., an absorbing agent provided herein). In some embodiments, about 1% to about 25% (w / w) of a composition provided herein is an absorbing agent (e.g., an absorbing agent provided herein). In certain embodiments, about 2% to about 15% (w / w) of a composition provided herein is an absorbing agent (e.g., an absorbing agent provided herein). [Oil4]    In certain embodiments, a composition (e.g., a composition provided herein) is an absorbing agent, such as silica. In certain embodiments, about 0.01% to about 40% (w / w) of a composition provided herein is silica. In some embodiments, about 1% to about 25% (w / w) of a composition provided herein is silica. In certain embodiments, about 2% to about 15% (w / w) of a composition provided herein is silica. In specific embodiments, about 6% to about 20% (w / w) of a composition provided herein is silica. In still more specific embodiments, about 2% to about 4% (w / w) of a composition provided herein is silica. In yet more specific embodiments, about 12% to about 16% (w / w) of a composition provided herein is silica. In still more specific embodiments, about 0.5% to about 5% (w / w) of a composition provided herein is silica. In yet more specific embodiments, about 8% (w / w) of a composition provided herein is silica. In still more specific embodiments, about 25% (w / w) of a composition provided herein is silica. In yet more specific embodiments, about 10% (w / w) of a composition provided herein is silica. In still more specific embodiments, about 25% (w / w) of a composition provided herein is silica,

[0115] In some embodiments, a composition provided herein comprises silica at about 0,01% to about 40% ( w / w) of a total weight of the composition. In some embodiments, about 0.01% to about 0.1%, about 0,01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2%, about 0.01% to about 5%, about 0.01% to about 8%, about 0.01% to about 10%, about 0.01% to about 15%, about 0.01% to about 23%, about 0.01% to about 30%, about 0.01 % to about 40%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.1% to about 2%, about 0.1% to about 5%, about 0.1% to about 8%, about 0.1% to about 10%, about 0.1% to about 15%, about 0.1% to about 23%, about 0.1% to about 30%, about 0.1% to about 40%, about 0.5% to about 1%, about 0.5% to about 2%, about 0.5% to about 5%, about ¢).5% to about 8%, about 0.5% to about 10%, about 0.5% to about 15%, about 0.5% to about 23%, about 0.5% to about 30%, about 0.5% to about 40%, about 1% to about 2%, about 1% to about 5%, about 1% to about 8%, about 1% to about 10%, about 1% to about 15%, about 1% to about 23%, about 1% to about 30%, about 1% to about 40%, about 2% to about 5%, about 2% to about 8%, about 2% to about 10%, about 2% to about 15%, about 2% to about 23%, about 2% to about 30%, about 2% to about 40%, about 5% to about 8%, about 5% to about 10%, about 5% to about 15%, about 5% to about 23%, about 5% to about 30%, about 5% to about 40%, about 8% to about 10%, about 8% to about 15%, about 8% to about 23%, about 8% to about 30%, about 8% to about 40%, about 10% to about 15%, about 10% to about 23%, about 10% to about 30%, about 10% to about 40%, about 15% to about 23%, about 15% to about 30%, about 15% to about 40%, about 23% to about 30%, about 23% to about 40%, or about 30% to about 40% (w / w) of a composition provided herein comprises silica. In some embodiments, about 0.01%, about 0.1%, about 0.5%, about 1%, about 2%, about 5%, about 8%, about 10%, about 15%, about 23%, about 30%, or about 40% (w / w) of a composition provided herein comprises silica. In some embodiments, at least about 0.01%, about 0.1%, about 0.5%, about 1%, about 2%, about 5%, about 8%, about 10%, about 15%, about 23%, or about 30% (w / w) of a composition provided herein is silica. In some embodiments, not more than about 0.1%, about 0.5%, about 1%, about 2%, about 5%, about 8%, about 10%, about 15%, about 23%, about 30%, or about 40% (w / w) of a composition provided herein is silica.

[0116] In some instances, the addition of silica to a composition provided herein is useful for reducing oils and / or sebum (e.g., in the scalp or hair of an individual).

[0117] In some aspects, compositions (e.g., a composition provided herein) comprise a sebum regulating agent. In specific embodiments, additional agents of composition (e.g., a composition provided herein) comprise a sebum regulating agent. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one sebum regulating agent, two sebum regulating agents, three sebum regulating agents, four sebum regulating agents, five sebum regulating agents, or more. In some instances, sebum regulating agents (e.g., a sebum regulating agent provided herein) are useful as sebum regulators (e.g., exfoliating and regulating levels of sebum on the scalp of an individual), and their inclusion in compositions (e.g., a composition provided herein, such as a non-aerosol formulation) furthers such purpose. In certain instances, sebum regulating agents are useful for other inherent properties, such as antioxidant, soothing, regenerative and tissue repair activities (e.g,, in an individual). In certain embodiments, sebum regulating agents provided herein (e.g., microalga extracts and metabolites) possess biochemical characteristics and contain bioactive compounds (e.g., with antimicrobial properties). In certain instances, sebum regulating agents provided herein (e.g., Tetraselmis Suecica extract) produce vitamin C which is a reactive oxygen species scavenger and protect against lipid hydroperoxy! radical reduction; and further, such sebum regulating agents are rich in carotenoids such as xanthophylls, lutein, violaxanthin, neoxanthin, T. suecica antheraxanthin and loroaxanthin esters. In some instances, sebum regulating agents provided herein have emulsifying and foaming properties (e.g., useful for reducing sebum and other oils in individuals). [bl 18]    In certain embodiments, a sebum regulating agent (e.g., a sebum regulating agent provided herein) can comprise tea tree oils and / or extracts (e.g., green tea emulsions), salicylic acids, fruit extracts (e.g., avocado extract), microalga extracts, and the like. In some embodiments, a sebum regulating agent (e.g., a sebum regulating agent provided herein) can comprise salicylic acid, microalgae extracts, green tea emulsions, avocado extract, Opuntia ficus-indica stem extract, Anetholea anisate leaf extract, Tetraselmis Suecica extract, Alteromonas ferment extract, Pseudoalteromonas ferment extract, Corylus avellana leaf extract, Phyllanthus emblica fruit extract, Saccharum offlcinarum (sugarcane) extract, Rhodomyrtus tomentosa fruit extract, Hedychium coronarium root extract, Epilobium angustifolium flower / leaf / stem extract, Tremella fuciformis sporocarp extract, salicylic acid, and / or combinations of one or more thereof. In specific embodiments, a sebum regulating agent in a composition (e.g., a composition provided herein) comprises Tetraselmis Suecica extract. In yet more specific embodiments, a sebum regulating agent in a composition (e.g., a composition provided herein) comprises green tea emulsions.

[0119] In certain embodiments, about 0.0001% to about 1% (w.Av) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In some embodiments, about .0005% to about 0.5% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In certain embodiments, about 0.001% to about 0,05% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In specific embodiments, about 0.005% to about 0.015% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In yet more specific embodiments, about 0.006% to about 0.01% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In still more specific embodiments, about 0.0089% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In yet more specific embodiments, about 0.5% to about 0.8% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In still more specific embodiments, about 0,002% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In specific embodiments, the sebum regulating agent, comprises Tetraselmis Suecica extract.

[0120] In some embodiments, a composition provided herein comprises a sebum regulating agent (e.g., a sebum regulating agent provided herein) at about 0.001% to about 1% (w / w) of the composition. In some embodiments, about 0,001% to about 0.002%, about 0.001% to about 0.003%, about 0.001% to about 0,005%, about. 0.001% to about 0.006%, about 0.001% to about 0.008%, about 0.001% to about 0.0089%, about 0.001% to about 0.01%, about 0.001% to about 0.05%, about. 0.001% to about 0.1%, about. 0.001% to about 0.5%, about 0.001% to about 1%, about 0.002% to about 0.003%, about 0.002% to about 0.005%, about 0.002% to about 0.006%, about 0.002% to about 0.008%, about. 0.002% to about 0.0089%, about 0.002% to about 0.01%, about 0.002% to about 0.05%, about 0.002% to about 0.1%, about 0.002% to about 0.5%, about 0.002% to about 1%, about 0.003% to about 0.005%, about 0.003% to about 0.006%, about 0.003% to about 0.008%, about 0.003% to about 0.0089%, about 0.003% to about 0.01%, about 0.003% to about 0.05%, about 0.003% to about 0.1%, about 0.003% to about 0.5%, about 0.003% to about 1%, about 0.005% to about 0.006%, about 0.005% to about 0.008%, about 0.005% to about 0.0089%, about 0.005% to about 0.01%, about 0.005% to about 0.05%, about 0.005% to about 0.1%, about 0.005% to about 0.5%, about 0.005% to about 1%, about 0.006% to about 0.008%, about 0.006% to about 0.0089%, about 0.006% to about 0.01%, about 0.006% to about 0.05%, about 0.006% to about 0.1%, about 0.006% to about 0.5%, about 0.006% to about 1%, about 0.008% to about 0.0089%, about 0.008% to about 0.01%, about 0.008% to about 0.05%, about 0.008% to about 0.1%, about 0.008% to about 0.5%, about 0.008% to about 1%, about 0.0089% to about 0.01%, about 0.0089% to about 0.05%, about 0.0089% to about 0.1%, about 0.0089% to about 0.5%, about 0.0089% to about 1%, about 0.01% to about 0.05%, about 0.01% to about 0.1%, about 0.01 % to about 0.5%, about 0.01% to about 1%, about 0.05% to about 0.1%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.1% to about 0.5%, about 0.1 % to about 1%, or about 0.5% to about 1% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In some embodiments, about 0.001%, about 0.002%, about 0.003%, about 0.005%, about 0.006%, about 0,008%, about 0.0089%, about 0.01%, about 0.05%, about 0.1%, about 0.5%, or about 1% (w / w) of a composition provided herein is a seburn regulating agent (e.g., a sebum regulating agent provided herein). In some embodiments, at least about 0.001 %, about 0.002%, about 0.003%, about 0.005%, about 0.006%, about 0.008%, about 0.0089%, about 0.01%, about 0.05%, about 0.1%, or about 0.5% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein). In some embodiments, not more than about 0.002%, about 0.003%, about 0.005%, about 0.006%, about 0.008%, about 0.0089%, about 0.01%, about 0.05%, about 0.1%, about 0.5%, or about 1% (w / w) of a composition provided herein is a sebum regulating agent (e.g., a sebum regulating agent provided herein).

[0121] In some aspects, compositions (e.g., a composition provided herein) comprise an odor control agent. In some embodiments, the odor control agent comprises fullerene encapsulated in silica, magnesium hydroxide, magnesium carbonate hydroxide, shikimic acid, zinc pyrrolidone carboxylate, glycerin, Morhula citrifolia callus culture lysate, citric acid, maltodextrin, or soy ethyl morpholinium ethosulfate, or a combination of two or more thereof.

[0122] In some aspects, compositions (e.g., a composition provided herein) comprise a solvent. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise a solvent. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one solvent, two solvents, three solvents, four solvents, five solvents, or more. In certain embodiments, a solvent (e.g., a solvent provided herein) is used to additional agents of a composition (e.g., a composition provided herein, such as a non-aerosol formulation).

[0123] In some embodiments, solvents (e.g., a solvent provided herein) comprise any suitable solvent (such as an alcohol, water, or the like). In certain embodiments, solvents can comprise polar solvents, nonpolar solvents, water, alcohols (e.g., ethanol), denatured alcohols (e.g., denatured ethanol), polyols (e.g., glycerin), glycols, sugars (e.g., glucose, fructose, or the like), polyethylene glycols, and / or combinations of one or more thereof. In some embodiments, solvents can comprise water, mannitol, dimethyl isosorbide, triethyl citrate, phenethyl benzoate, dicaprylyl maleate, dilinoleic acid / propanediol copolymer, denatured ethanol, denatured methanol, denatured propanol, denatured isopropyl alcohol, denatured butanol, denatured pentanol, denatured hexanol, methanol, ethanol, propanol, isopropyl alcohol, butanol, pentanol, hexanol, glycerin, buty lene glycol, isoprene glycol, propylene glycol, dipropylene glycol, propanediol, isopentyldiol, polyethylene glycols, sorbitol, glucose, fructose, maltose, lactose, sucrose, PEG-4, PEG-6, PEG-8, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18, PEG-20, and / or combinations of one or more thereof.

[0124] In certain embodiments, a solvent in a composition (e.g., a composition provided herein) comprises water. In some embodiments, the solvent in a composition (e.g., a composition provided herein) comprises glycerin. In certain embodiments, the solvent in a composition (e.g., a composition provided herein) comprises mannitol. In some embodiments, a solvent in a composition provided herein comprises an alcohol. In specific embodiments, the solvent, in a composition (e.g., a composition provided herein) comprises denatured ethanol.

[0125] In certain embodiments, solvents (e.g., total solvent) comprise about 35% to about 99% by weight (w / w) of a composition (e.g., a composition provided herein). In some embodiments, solvents comprise about 60% to about. 97% (w / w) of the composition. In certain embodiments, solvents comprise about 80% to about 95% (w / w) of the composition.

[0126] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent. In certain embodiments, about 15% to about 95% (w / w) of a composition provided herein comprises a solvent (e.g., a solvent provided herein). In some embodiments, about 30% to about 90% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein). In certain embodiments, about 45% to about 85% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein).

[0127] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent, such as water. In certain embodiments, the solvent in a composition (e.g., a composition provided herein) comprises water. In certain embodiments, about 15% to about 95% (w / w) of a composition provided herein is water. In some embodiments, about 30% to about 90% (w / w) of a composition provided herein is water. In certain embodiments, about 45% to about 85% (w / w) of a composition provided herein is water. In specific embodiments, about 65% to about 70% (w / w) of a composition provided herein is water. In yet more specific embodiments, about 20% to about 40% (w / w) of a composition provided herein is water. In still more specific embodiments, about 40% to about 45% (w / w) of a composition provided herein is water.

[0128] In some embodiments, a composition provided herein comprises water at about 15% to about 95% by weight (w / w) of the composition. In some embodiments, a composition provided herein comprises water (% w / w) at about 15% to about 25%, about 15% to about 40%, about 15% to about 45%, about 15% to about 55%, about 15% to about 60%, about 15% to about 65*0,. about 15% to about 68%, about 15% to about 70%, about 15% to about 75%, about 15% to about 85%, about 15% to about 95%, about 25% to about 40%, about 25% to about 45%, about 25% to about 55%, about 2.5% to about 60%, about 25% to about 65%, about 25% to about 68%, about 25% to about 70%, about 25% to about 75%, about 25% to about 85%, about 25% to about 95%, about 40% to about 45%, about 40% to about 55%, about 40% to about 60%, about 40% to about 65%, about 40% to about 68%, about 40% to about 70%, about 40% to about 75%, about 40% to about 85%, about 40% to about 95%, about 45% to about 55%, about 45% to about 60%, about 45% to about 65%, about 45% to about 68%, about 45% to about 70%, about 45% to about 75%, about 45% to about 85%, about 45% to about 95%, about 55% to about 60%, about 55% to about 65%, about 55% to about 68%, about 55% to about 70%, about 55% to about 75%, about 55% to about 85%, about 55% to about 95%, about 60% to about 65%, about 60% to about 68%, about 60% to about 70%, about 60% to about 75%, about 60% to about 85%, about 60% to about 95%, about 65% to about 68%, about 65% to about 70%, about 65% to about 75%, about 65% to about 85%, about 65% to about 95%, about 68% to about 70%, about 68% to about 75%, about 68% to about 85%, about 68% to about 95%, about 70% to about 75%, about 70% to about 85%, about 70% to about 95%, about 75% to about 85%, about 75% to about 95%, or about 85% to about 95% (w / w). In some embodiments, about 15%, about 25%, about 40%, about 45%, about 55%, about 60%, about 65%, about 68%, about 70%, about 75%, about 85%, or about 95% (w / wj of a composition provided herein is water. In some embodiments, at least about 15%, about 25%, about 40%, about 45%, about 55%, about 60%, about 65%, about 68%, about 70%, about 75%, or about 85% (w / w) of a composition provided herein is water. In some embodiments, not more than about 25%, about 40%, about 45%, about 55%, about 60%, about 65%, about 68%, about 70%, about 75%, about 85%, or about 95% (w / w) of a composition provided herein is water.

[0129] In certain instances, the addition of water to a composition provided herein is useful for dissolving one or more additional agents of the composition.

[0130] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent (e.g., a solvent provided herein). In certain embodiments, about 0.01% to about 10% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein. In some embodiments, about 0.05% to about 5% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein. In certain embodiments, about 0.1% to about 1% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein.

[0131] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent, such as glycerin. In certain embodiments, about 0.01% to about 10% (w / w) of a composition provided herein is glycerin. In some embodiments, about 0.05% to about 5% (w / w) of a composition provided herein is glycerin. In certain embodiments, about ¢). 1% to about 1% (w / w) of a composition provided herein is glycerin. In some embodiments, about 1% to about 5% (w / w) of a composition provided herein is glycerin. In specific embodiments, about 0.1% to about 0.2% (w / w) of a composition provided herein is glycerin. In yet more specific embodiments, about 0.3% to about 0.5% (w / w) of a composition provided herein is glycerin. In still more specific embodiments, about 1.4% to about 2.5% (w / w) of a composition provided herein is glycerin. In yet more specific embodiments, about 0.4% (w / w) of a composition provided herein is glycerin. In still more specific embodiments, about 1% (wAv) of a composition provided herein is glycerin. In yet more specific embodiments, about 5% (w / w) of a composition provided herein is glycerin.

[0132] In some embodiments, a composition provided herein comprises glycerin at about 0.01% to about 10% (w / w ) of the composition. In some embodiments, a composition provided herein comprises glycerin at about 0.01% to about 0.1%, about 0.01% to about 0.2%, about 0.01% to about 0.3%, about 0.01% to about 0.4%, about 0.01% to about 0.5%, about 0.01% to about 0.6%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.01% to about 7.5%, about 0.01% to about 10%, about 0.1% to about 0.2%, about 0.1% to about 0.3%, about 0.1% to about 0.4%, about 0.1% to about 0.5%, about 0.1 % to about 0.6%, about 0.1% to about 1 %, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.1% to about 7.5%, about 0.1% to about 10%, about 0.2% to about 0.3%, about 0.2% to about 0.4%, about 0.2% to about 0.5%, about 0.2% to about 0.6%, about 0.2% to about 1%, about 0,2% to about 2.5%, about 0.2% to about 5%, about 0.2% to about 7.5%, about 0.2% to about 10%, about 0.3% to about 0.4%, about 0.3% to about 0.5%, about 0.3% to about 0.6%, about 0.3% to about 1%, about 0.3% to about 2.5%, about 0.3% to about 5%, about 0.3% to about 7.5%, about 0.3% to about 10%, about 0.4% to about 0.5%, about 0.4% to about 0.6%, about 0.4% to about 1%, about 0.4% to about 2.5%, about 0.4% to about 5%, about 0.4% to about 7.5%, about 0.4% to about 10%, about 0.5% to about 0.6%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 0.5% to about 7.5%, about 0.5% to about 10%, about 0.6% to about 1%, about 0.6% to about 2.5%, about 0.6% to about 5%, about 0.6% to about 7.5%, about 0.6% to about 10%, about 1% to about 2.5%, about 1% to about 5%, about 1% to about 7.5%, about 1% to about 10%, about 2.5% to about 5%, about 2.5% to about 7.5%, about 2.5% to about 10%, about 5% to about 7.5%, about 5% to about 10%, or about 7.5% to about 10% (w / w). In some embodiments, about 0.01%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 1%, about 2.5%, about 5%, about 7.5%, or about 10% of the composition. In some embodiments, at least about 0.01%, about 0.1%, about 0,2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 1%, about 2.5%, about 5%, or about 7.5% (w / w) of a composition provided herein is glycerin. In some embodiments, not more than about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 1%, about 2.5%, about 5%, about 7.5%, or about 10% (w / w) of a composition provided herein is glycerin.

[0133] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent (e.g., a solvent provided herein). In certain embodiments, about 0.001% to about 5% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein). In some embodiments, about 0.01% to about 1% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein). In certain embodiments, about 0.02% to about 0.1% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein).

[0134] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent, such as mannitol. In certain embodiments, about 0.001% to about 5% (w / w) of a composition provided herein is mannitol. In some embodiments, about 0.01% to about 1% (w / w) of a composition provided herein is mannitol. In certain embodiments, about 0,02% to about 0.1% (w / w) of a composition provided herein is mannitol. In some embodiments, about 0.1% to about 1% (w / w) of a composition provided herein is mannitol. In specific embodiments, about 0.02% to about 0.1% (w / w) of a composition provided herein is mannitol. In yet more specific embodiments, about 0.03% to about 0.04% (w7w) of a composition provided herein is mannitol. In still more specific embodiments, about 0.05% to about 0.07% (w / w) of a composition provided herein is mannitol. In yet more specific embodiments, about 0.035% (w / w) of a composition provided herein is mannitol. In still more specific embodiments, about 0.3% (w / w) of a composition provided herein is mannitol. In yet more specific embodiments, about 1% (w / w) of a composition provided herein is mannitol.

[0135] In some embodiments, a composition provided herein comprises mannitol at about 0.001% to about 5% (w / 'w) of the composition. In certain embodiments, a composition provided herein comprises mannitol at about 0.001% to about 0.01%, about 0.001% to about 0.02%, about 0.001% to about 0.03%, about 0.001% to about 0.035%, about 0.001% to about 0.04%, about 0.001% to about 0.06%, about 0.001% to about 0.1%, about 0.001% to about 0.5%, about 0.001% to about 1%, about 0.001% to about 2.5%, about 0.001% to about 5%, about 0.0 J % to about 0.02%, about 0.01% to about 0.03%, about 0.01% to about 0.035%, about 0.01% to about 0.04%, about ¢).01% to about 0.06%, about ¢).01% to about 0.1%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.02% to about 0.03%, about 0.02% to about 0.035%, about 0.02% to about 0.04%, about 0.02% to about 0.06%, about 0.02% to about 0.1%, about 0.02% to about 0.5%, about 0.02% to about 1%, about 0.02% to about 2.5%, about 0.02% to about 5%, about 0.03% to about 0.035%, about 0.03% to about 0.04%, about 0.03% to about 0.06%, about 0.03% to about 0.1%, about 0.03% to about 0.5%, about 0.03% to about 1%, about 0.03% to about 2,5%, about 0.03% to about 5%, about 0.035% to about 0.04%, about 0.035% to about 0.06%, about 0.035% to about 0.1%, about 0.035% to about 0.5%, about 0.035% to about 1%, about 0.035% to about 2.5%, about 0.035% to about 5%, about 0.04% to about 0.06%, about 0.04% to about 0.1%, about 0.04% to about 0.5%, about 0.04% to about 1%, about 0.04% to about 2.5%, about 0.04% to about 5%, about 0.06% to about 0.1%, about 0.06% to about 0.5%, about 0.06% to about 1%, about 0.06% to about 2.5%, about 0.06% to about 5%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0,5% to about 5%, about 1% to about 2.5%, about 1% to about 5%, or about 2.5% to about 5% (w / w). In some embodiments, about 0.001%, about 0.01%, about 0.02%, about. 0.03%, about 0.035%, about 0.04%, about 0.06%, about. 0.1%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of the composition. In some embodiments, at least about 0.001%, about 0.01%, about 0.02%, about 0.03%, about 0.035%, about 0.04%, about 0.06%, about 0.1%, about 0.5%, about 1%, or about 2.5% (w / w) of a composition provided herein is mannitol. In some embodiments, not more than about 0.01%, about 0.02%, about 0.03%, about 0.035%, about 0.04%, about 0.06%, about 0,1%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of a composition provided herein is mannitol.

[0136] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent (e.g., a solvent provided herein). In certain embodiments, about 1% to about 60% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein). In some embodiments, about 5% to about 40% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein). In certain embodiments, about 10% to about 30% (w / w) of a composition provided herein is a solvent (e.g., a solvent provided herein). In some embodiments, the odor binding protein does not substantially denature or unfold in the presence of alcohol, such as denatured ethanol. In some instances, die odor binding protein does not substantially denature or unfold in die presence of about 20% (w / w), about 30% (w / w), about 40% (w / w), about 50% (w / w), or about 60% (w / w) of alcohol, such as denatured ethanol. In some embodiments, the solvent improves a dry time of the composition.

[0137] In certain embodiments, a composition (e.g., a composition provided herein) comprises a solvent, such as an (e.g., denatured) alcohol. In certain embodiments, about 1% to about 60% (w / w) of a composition provided herein is denatured ethanol. In some embodiments, about 5% to about 40% (w / w) of a composition provided herein is denatured ethanol. In certain embodiments, about 10% to about 30% (w / w) of a composition provided herein is denatured ethanol. In some embodiments, about 10% to about 20% (w / w) of a composition provided herein is denatured ethanol. In some embodiments, about 25% to about 50% (w / w) of a composition provided herein is denatured ethanol. In some embodiments, about 1% to about 20% (w / w) of a composition provided herein is denatured ethanol. In specific embodiments, about 20% to about 25% (w / w) of a composition provided herein is denatured ethanol In yet more specific embodiments, about 45% to about 50% (w / w) of a composition provided herein is denatured ethanol. In still more specific embodiments, about 5% to about 15% (w / w) of a composition provided herein is denatured ethanol. In yet more specific embodiments, about 22% (w / w) of a composition provided herein is denatured ethanol. In still more specific embodiments, about 35% (w / w) of a composition provided herein is denatured ethanol. In yet more specific embodiments, about 5% (w / w) of a composition provided herein is denatured ethanol. In some embodiments, a composition provided herein is denatured ethanol at about 1% to about 60% (w / w) of the composition. In some embodiments, about 1% to about 5%, about 1% to about 10%, about 1% to about 15%, about 1% to about 20%, about 1% to about 21%, about 1% to about 22%, about 1% to about 25%, about 1% to about 30%, about 1% to about 40%, about 1% to about 50%, about 1% to about 60%, about 5% to about 10%, about 5% to about 15%, about 5% to about 20%, about 5% to about 21%, about 5% to about 22%, about 5% to about 25%, about 5% to about 30%, about 5% to about 40%, about 5% to about 50%, about 5% to about 60%, about 10% to about 15%, about 10% to about 20%, about 10% to about 21%, about 10% to about 22%, about 10% to about 25%, about 10% to about 30%, about 10% to about 40%, about 10% to about 50%, about 10% to about 60%, about 15% to about 20%, about 15% to about 21%, about 15% to about 22%, about 15% to about 25%, about 15% to about 30%, about 15% to about 40%, about 15% to about 50%, about 15% to about 60%, about 20% to about 21%, about 20% to about 22%, about 20% to about 25%, about 20% to about 30%, about 20% to about 40%, about 20% to about 50%, about 20% to about 60%, about 21% to about 22%, about 21% to about 25%, about 21% to about 30%, about 21% to about 40%, about 21% to about 50%, about 21% to about 60%, about 22% to about 25%, about 22% to about 30%, about 22% to about 40%, about 22% to about 50%, about 22% to about 60%, about 25% to about 30%, about 25% to about 40%, about 25% to about 50%, about 25% to about 60%, about 30% to about 40%, about 30% to about 50%, about 30% to about 60%, about 40% to about 50%, about 40% to about 60%, or about 50% to about 60% of a composition provided herein is denatured ethanol. In some embodiments, about 1%, about 5%, about 10%, about 15%, about 20%, about 21%, about 22%, about 25%, about 30%, about 40%, about 50%, or about 60% of a composition provided herein is denatured ethanol. In some embodiments, at least about 1%, about 5%, about 10%, about 15%, about 20%, about 21%, about 22%, about 25%, about 30%, about 40%, or about 50% (w / w) of a composition provided herein is denatured ethanol. In some embodiments, not more than about 5%, about 10%, about 15%, about 20%, about 21%, about 22%, about 25%, about 30%, about 40%, about 50%, or about 60% (w / w) of a composition provided herein is denatured ethanol.

[0139] In certain instances, the addition of denatured alcohol to a composition provided herein is useful for dissolving additional components of compositions provided herein (e.g., without interfering with active ingredients (e.g., an odor binding protein provided herein) of the same).

[0140] In some aspects, compositions (e.g., a composition provided herein) comprise a humectant. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) a humectant. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one humectant, two humectants, three humectants, four humectants, five humectants, or more. In certain instances, a humectant (e.g., a humectant provided herein) is useful for moisturizing (such as moisturizing the hair and / or scalp of an individual). Humectants are added to compositions (e.g., a composition provided herein, such as a non-aerosol formulation) for such purposes. [0141 ] In some embodiments, the humectants comprise any suitable humectant. In certain embodiments, a humectant comprises a hyaluronate, glycol, sorbitol, sugar (e.g., glucose), carbocyclic sugar, (e.g., sugar) alcohol, or a combination of two or more thereof. In some embodiments, the humectant comprises 1,2,6 hexanetriol, dipropylene glycol, glycerin, butylene glycol, caprylyl glycol, pentylene glycol, isopentyldiol, hexylene glycol, panthenol, phytantriol, propylene glycol, propanediol, sodium PCA, sorbitol, triethylene glycol, polyglyceryl sorbitol, glucose, fructose, mannitol, xylitol, inositol, trehalose, polydextrose, potassium PCA, hydrogenated honey, hyaluronic acid, hydrolyzed hyaluronic acid, sodium hyaluronate, inositol, erythritol, capryl glycol, acetamidoethoxyethanol, or a combination of two or more thereof.

[0142] In specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises glycerin. In yet more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises sorbitol. In still more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises potassium PCA. In yet more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises mannitol. In yet more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises propylene glycol. In still more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises hexanetriol. In yet more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises sodium hyaluronate. In still more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises hydrolyzed hyaluronic acid. In yet more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises hydrogenated honey. In still more specific embodiments, a humectant in a composition (e.g., a composition provided herein) comprises acetamidoethoxyethanol.

[0143] In certain embodiments, humectants (e.g., total humectant) comprise about 0.01% to about 5% by weight (w / w) of a composition (e.g., a composition provided herein). In some embodiments, humectants comprise about 0.1% to about 2% (w / w) of the composition. In certain embodiments, humectants comprise about 0.25% to about 1% (w / w) of the composition.

[0144] In certain embodiments, a composition provided herein comprises a humectant (e.g., a humectant provided herein). In some embodiments, about 0.01% to about 10% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.05% to about 5% of a composition provided herein is a humectant (e.g., a humectant provided herein). In certain embodiments, about 0,1% to about 1% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein).

[0145] In certain embodiments, a composition provided herein comprises a humectant such as glycerin. In some embodiments, abou t 0.01% to about 10% (w / w) of a composition provided herein is glycerin. In certain embodiments, about 0.05% to about 5% of a composition provided herein is glycerin. In certain embodiments, about 0.1% to about 1% (wAv) of a composition provided herein is glycerin. In some embodiments, about 1% to about 5% (w / w) of a composition provided herein is glycerin. In specific embodiments, about 0.1% to about 0.2% (w / w) of a composition provided herein is glycerin. In yet more specific embodiments, about 0.3% to about 0.5% (w / w) of a composition provided herein is glycerin. In still more specific embodiments, about 1.4% to about 2.5% (w / w) of a composition provided herein is glycerin. In yet more specific embodiments, about 0.4% (w / w) of a composition provided herein is glycerin. In still more specific embodiments, about 1% (w / w) of a composition provided herein is glycerin. In yet more specific embodiments, about 5% (w / w) of a composition provided herein is glycerin.

[0146] In some embodiments, a composition provided herein comprises glycerin at about 0.01% to about 10% (w / w) of the composition. In some embodiments, a composition provided herein comprises glycerin at about 0.01% to about 0.1%, about 0.01% to about 0.2%, about 0.01% to about 0.3%, about 0.01% to about 0.4%, about 0.01% to about 0.5%, about 0.01% to about 0.6%, about 0.01% to about 1%, about 0.01% to about 2,5%, about 0.01% to about 5%, about 0.01% to about 7.5%, about 0.01% to about 10%, about 0.1% to about 0.2%, about 0.1% to about 0.3%, about 0.1% to about 0.4%, about 0.1 % to about 0.5%, about 0.1% to about 0.6%, about 0.1% to about 1%, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.1% to about 7.5%, about 0.1% to about 10%, about 0.2% to about 0.3%, about 0.2% to about 0.4%, about 0.2% to about 0.5%, about 0.2% to about 0.6%, about 0.2% to about 1%, about 0.2% to about 2.5%, about 0.2% to about 5%, about ¢).2% to about 7.5%, about 0.2% to about 10%, about 0.3% to about 0.4%, about 0.3% to about 0.5%, about 0.3% to about 0.6%, about 0.3% to about 1%, about 0.3% to about 2.5%, about 0.3% to about 5%, about 0.3% to about 7.5%, about ¢).3% to about 10%, about 0.4% to about 0.5%, about 0.4% to about 0.6%, about 0.4% to about 1%, about 0.4% to about 2.5%, about 0.4% to about 5%, about 0.4% to about 7.5%, about 0.4% to about 10%, about 0.5% to about 0.6%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 0.5% to about 7.5%, about 0.5% to about 10%, about 0.6% to about 1%, about 0.6% to about 2.5%, about 0.6% to about 5%, about 0.6% to about 7.5%, about 0.6% to about 10%, about 1% to about 2.5%, about 1% to about 5%, about 1% to about 7.5%, about 1% to about 10%, about 2.5% to about 5%, about 2.5% to about 7.5%, about 2.5% to about 10%, about 5% to about 7.5%, about 5% to about 10%, or about 7.5% to about 10% (w / w). In some embodiments, about 0.01%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 1%, about 2.5%, about 5%, about 7.5%, or about 10%. In some embodiments, a composition provided herein comprises glycerin at least about 0.01%, about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 1%, about 2.5%, about 5%, or about 7.5% (w / w) of the composition. In some embodiments, not more than about 0.1%, about 0.2%, about 0.3%, about 0.4%, about 0.5%, about 0.6%, about 1%, about 2.5%, about 5%, about 7.5%, or about 10% (w / w) of a composition provided herein is glycerin.

[0147] In certain embodiments, a composition (e.g., a composition provided herein) comprises a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.001% to about 5% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In some embodiments, about 0.01% to about 1% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.02% to about 0.1 % (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein).

[0148] In certain embodiments, a composition (e.g., a composition provided herein) comprises a humectant, such as mannitol. In certain embodiments, about 0.001% to about 5% (w / w) of a composition provided herein is mannitol. In some embodiments, about 0.01% to about 1% (w / w) of a composition provided herein is mannitol. In certain embodiments, about 0.02% to about 0.1 % (w / w) of a composition provided herein is mannitol. In some embodiments, about 0,1% to about 1% (w / w) of a composition provided herein is mannitol. In specific embodiments, about 0.02% to about 0.1% (w / w) of a composition provided herein is mannitol. In yet more specific embodiments, about 0.03% to about 0.04% (w / w) of a composition provided herein is mannitol. In still more specific embodiments, about 0,05% to about 0.07% (w / w) of a composition provided herein is mannitol. In yet more specific embodiments, about 0.035% (w / w) of a composition provided herein is mannitol. In still more specific embodiments, about 0.3% (w / w) of a composition provided herein is mannitol. In yet more specific embodiments, about 1% (w / w) of a composition provided herein is mannitol.

[0149] In some embodiments, a composition provided herein comprises mannitol at about 0.001% to about 5% (w / w) of the composition. In certain embodiments, a composition provided herein comprises mannitol at about 0,001% to about 0.01%, about 0.001% to about 0.02%, about 0.001% to about 0.03%, about 0.001% to about 0.035%, about 0.001% to about 0.04%, about 0.001% to about 0.06%, about 0.001% to about 0.1%, about 0.001% to about 0.5%, about 0.001% to about 1%, about 0.001% to about 2.5%, about 0.001% to about 5%, about 0.01% to about 0.02%, about 0.01% to about 0.03%, about 0.01% to about 0.035%, about 0.01 % to about 0.04%, about 0.01% to about 0.06%, about 0.01% to about 0.1%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.02% to about 0.03%, about 0.02% to about 0.035%, about 0.02% to about 0.04%, about 0.02% to about 0.06%, about 0.02% to about 0.1%, about 0.02% to about 0.5%, about 0.02% to about 1%, about 0.02% to about 2.5%, about 0.02% to about 5%, about 0.03% to about 0.035%, about 0.03% to about 0.04%, about 0.03% to about 0.06%, about 0.03% to about 0.1%, about 0.03% to about 0.5%, about 0.03% to about 1%, about 0.03% to about 2.5%, about 0.03% to about 5%, about 0.035% to about 0.04%, about 0.035% to about 0.06%, about 0.035% to about 0,1%, about 0.035% to about 0,5%, about 0.035% to about 1%, about 0.035% to about 2.5%, about 0.035% to about 5%, about 0.04% to about 0.06%, about 0.04% to about 0.1%, about 0,04% to about 0.5%, about 0.04% to about 1%, about 0.04% to about 2.5%, about 0.04% to about 5%, about 0.06% to about 0.1%, about 0.06% to about 0.5%, about 0.06% to about 1%, about 0.06% to about 2.5%, about 0.06% to about 5%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 1% to about 2.5%, about 1% to about 5%, or about 2.5% to about 5% (wAv). hr some embodiments, about 0.001%, about 0.01%, about 0.02%, about 0.03%, about 0.035%, about 0.04%, about 0.06%, about 0.1%, about 0.5%, about 1%, about 2,5%, or about 5% (w / w) of the composition. In some embodiments, at least about 0.001%, about 0.01%, about 0.02%, about 0.03%, about 0.035%, about 0.04%, about 0.06%, about 0.1%, about 0.5%, about 1%, or about 2.5% (w / w) of a composition provided herein is mannitol. In some embodiments, not more than about 0.01%, about 0.02%, about 0.03%, about 0.035%, about 0.04%, about 0.06%, about 0.1%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of a composition provided herein is mannitol.

[0150] In certain embodiments, a composition (e.g., a composition provided herein) comprises a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.0001% to about 2% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In some embodiments, about 0.0005% to about 1% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.001% to about 0.01% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). [0151 ]    In certain embodiments, a composition (e.g., a composition provided herein) comprises a humectant, such as sodium hyaluronate. In certain embodiments, about 0.0001% to about 2% (w / w) of a composition provided herein is sodium hyaluronate. In some embodiments, about. 0.0005% to about 1 % (w / w) of a composition provided herein is sodium hyaluronate. In certain embodiments, about 0.001% to about 0.001% (w / w) of a composition provided herein is sodium hyaluronate. In specific embodiments, about 0.1% to about 0.5% (w / w) of a composition provided herein is sodium hyaluronate. In yet more specific embodiments, about 0.001% to about 0.003% (w7w) of a composition provided herein is sodium hyaluronate. In still more specific embodiments, about 0.001% to about 0.002% (w / w) of a composition provided herein is sodium hyaluronate. In yet more specific embodiments, about 0.005% to about 0.009% (w / w) of a composition provided herein is sodium hyaluronate. In still more specific embodiments, about 1.0% to about 1.5% (w / w) of a composition provided herein is sodium hyaluronate. In yet more specific embodiments, about 0.001% of a composition provided herein is sodium hyaluronate. In still more specific embodiments, about 1.0% (w / w) of a composition provided herein is sodium hyaluronate. In yet more specific embodiments, about 0.0015% to about 0.002% (w / w) of a composition provided herein is sodium hyaluronate. In still more specific embodiments, about 0.0018% (w / w) of a composition provided herein is sodium hyaluronate.

[0152] In some embodiments, a composition provided herein comprises sodium hyaluronate at about 0.0001% to about 2% (w / w) of the composition. In some embodiments, about 0.0001% to about 0.0003%, about 0.0001% to about 0.0006%, about 0.0001% to about 0.0009%, about 0.0001% to about 0.0018%, about 0.0001% to about 0.0025%, about 0.0001% to about 0.01%, about 0.0001% to about 0.05%, about 0.0001% to about 0.1%, about 0.0001% to about 0.5%, about 0.0001% to about 1%, about 0.0001% to about 2%, about 0.0003% to about 0.0006%, about 0.0003% to about 0.0009%, about 0.0003% to about 0.0018%, about 0.0003% to about 0,0025%, about 0.0003% to about 0.01%, about 0.0003% to about 0.05%, about 0.0003% to about 0.1%, about 0.0003% to about 0.5%, about 0.0003% to about 1%, about 0,0003% to about 2%, about 0.0006% to about 0.0009%, about 0.0006% to about 0.0018%, about 0.0006% to about 0.0025%, about 0.0006% to about 0.01%, about 0.0006% to about 0.05%, about 0.0006% to about 0.1%, about 0.0006% to about 0.5%, about 0.0006% to about 1%, about 0.0006% to about 2%, about 0.0009% to about 0.0018%, about 0.0009% to about 0.0025%, about 0.0009% to about 0.01%, about 0.0009% to about 0.05%, about 0.0009% to about 0.1%, about 0.0009% to about 0.5%, about 0,0009% to about 1%, about 0.0009% to about 2%, about 0.0018% to about 0.0025%, about 0.0018% to about 0.01%, about 0.0018% to about 0.05%, about 0.0018% to about 0.1%, about 0.0018% to about 0.5%, about 0.0018% to about 1%, about 0.0018% to about 2%, about 0.0025% to about 0.01%, about 0.0025% to about 0.05%, about 0.0025% to about 0.1%, about 0.0025% to about 0.5%, about 0.0025% to about 1%, about 0.0025% to about 2%, about 0.01% to about 0.05%, about 0.01% to about 0.1%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2%, about 0.05% to about 0.1%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.05% to about 2%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.1% to about 2%, about 0.5% to about 1%, about 0.5% to about 2%, or about 1% to about 2% (w / w) of a composition provided herein is sodium hyaluronate. In some embodiments, about 0.0001%, about 0.0003%, about 0.0006%, about 0.0009%, about 0.0018%, about 0.002.5%, about 0.01%, about 0.05%, about 0,1%, about 0.5%, about 1%, or about 2% (w / w) of a composition provided herein is sodium hyaluronate. In some embodiments, at least about 0.0001%, about 0.0003%, about 0.0006%, about 0.0009%, about 0.0018%, about 0.0025%, about 0.01%, about 0.05%, about 0.1%, about 0.5%, or about 1% (w / w) of a composition provided herein is sodium hyaluronate. In some embodiments, not more than about 0.0003%, about 0.0006%, about 0.0009%, about 0.0018%, about 0.0025%, about 0.01%, about 0.05%, about 0.1%, about 0.5%, about 1%, or about 2% (w / w) of a composition provided herein is sodium hyaluronate.

[0153] In some embodiments, the sodium hyaluronate in the composition comprises a molecular weight (kDa). In some embodiments, the sodium hyaluronate comprises a molecular weight of about 100 kDa to about 2,000 kDa, about 100 kDa to about 1,800 kDa, about 100 kDa to about 1,600 kDa, about 100 kDa to about 1,400 kDa, about 100 kDa to about 1,200 kDa, about 100 kDa to about 1,000 kDa, about 100 kDa to about 800 kDa, about 100 kDa to about 600 kDa, about 100 kDa to about 400 kDa, about 100 kDa to about 200 kDa, about 200 kDa to about 2,000 kDa, about 200 kDa to about 1,800 kDa, about 200 kDa to about 1,600 kDa, about 200 kDa to about 1,400 kDa, about 200 kDa to about 1,200 kDa, about 2.00 kDa to about 1,000 kDa, about 200 kDa to about 800 kDa, about 200 kDa to about 600 kDa, about 200 kDa to about 400 kDa, about 500 kDa to about 2,000 kDa, about 500 kDa to about 1,800 kDa, about 500 kDa to about 1,600 kDa, about 500 kDa to about 1,400 kDa, about 500 kDa to about 1,200 kDa, about 500 kDa to about 1,000 kDa, about 500 kDa to about 800 kDa, about 500 kDa to about 600 kDa, about 100 kDa to about 2,000 kDa, about 200 kDa to about 1,800 kDa, about 300 kDa to about 1,600 kDa, about 400 kDa to about 1,400 kDa, about 500 kDa to about 1,200 kDa, about 600 kDa to about 1,000 kDa, or about 700 kDa to about 800 kDa.

[0154] In some instances, the addition of sodium hyaluronate to a composition provided herein is useful tor maintaining moisture in the hair of an individual. In certain instances, sodium hyaluronate is useful for exfoliating the scalp and strengthening the hair of an individual.

[0155] In certain embodiments, a composition (e.g., a composition provided herein) comprises a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.0001% to about 2% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In some embodiments, about 0.0005% to about 1% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein). In certain embodiments, about 0.001% to about 0.1% (w / w) of a composition provided herein is a humectant (e.g., a humectant provided herein).

[0156] In certain embodiments, a composition (e.g., a composition provided herein) comprises a humectant, such as (e.g., hydrolyzed) hyaluronic acid. In certain embodiments, about 0.0001% to about 2% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In some embodiments, about 0.0005% to about 1% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In certain embodiments, about 0.001% to about 0.1% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In certain embodiments, about 0.001% to about 0.01% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In some embodiments, about 0.1% to about 0.5% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In some embodiments, about 0.001% to about 0,004% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In some embodiments, about 1.0% to about 1.5% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In specific embodiments, about 0.005% to about 0.008% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In yet. more specific embodiments, about. 0,005% to about 0.008% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In still more specific embodiments, about 0.006% to about 0.007% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In yet more specific embodiments, about 0,01% to about 0.05% (w7w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In still more specific embodiments, about 0,007% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In yet more specific embodiments, about 1.5% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In still more specific embodiments, about 0.0004% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid.

[0157] In some embodiments, a composition provided herein comprises (e.g., hydrolyzed) hyaluronic acid at about 0.0001% to about 2% (w / w) of the composition. In some embodiments, about 0.0001% to about 0.0005%, about 0.0001% to about 0,001%, about 0.0001% to about 0.003%, about 0.0001% to about 0.0064%, about 0.0001% to about 0.0085%, about 0.0001’% to about 0.01%, about 0.0001% to about. 0.05%, about 0.0001% to about 0.1%, about 0.0001% to about 0.5%, about. 0.0001% to about 1%, about 0.0001% to about 2%, about 0.0005% to about 0.001%, about 0.0005% to about 0.003%, about 0.0005% to about 0.0064%, about 0.0005% to about 0.0085%, about 0.0005% to about 0.01%, about 0.0005% to about 0.05%, about 0.0005% to about 0.1%, about ¢).00()5% to about 0.5%, about 0.0005% to about 1%, about 0.0005% to about 2%, about 0.001% to about 0.003%, about 0.001% to about 0,0064%, about 0,001% to about 0.0085%, about 0.001% to about 0.01%, about 0.()()1% to about 0.05%, about 0.001% to about 0.1%, about 0.001% to about 0.5%, about 0.001% to about 1%, about 0.001% to about 2%, about 0,003% to about 0.0064%, about ¢).0()3% to about 0.0085%, about 0.003% to about 0.01%, about 0.003% to about 0.05%, about 0.003% to about 0.1%, about 0.003% to about 0.5%, about 0.003% to about 1%, about 0.003% to about 2%, about 0.0064% to about 0.0085%, about 0.0064% to about 0.01%, about 0.0064% to about 0.05%, about 0.0064% to about 0.1%, about 0.0064% to about 0.5%, about 0.0064% to about 1%, about 0.0064% to about 2%, about 0.0085% to about 0.01%, about 0.0085% to about 0.05%, about 0.0085% to about 0.1%, about 0.0085% to about 0.5%, about ¢).0085% to about 1%, about 0.0085% to about 2%, about 0.01% to about. 0.05%, about 0.01% to about. 0.1%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2%, about 0.05% to about 0.1%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.05% to about. 2%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.1% to about 2%, about 0.5% to about 1%, about 0.5% to about 2%, or about 1% to about 2% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In some embodiments, about 0.0001%, about 0,0005%, about 0,001%, about 0.003%, about 0.0064%, about 0.0085%, about 0.01%, about 0.05%, about 0.1%, about 0.5%, about 1%, or about 2% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid. In some embodiments, at least about 0.0001%, about 0.0005%, about 0.001%, about 0.003%, about 0.0064%, about 0.0085%, about 0.01%, about 0.05%, about 0,1%, about 0.5%, or about 1% (w / w) of a composition provided herein is (e.g., hydrolyzed hyaluronic acid). In some embodiments, not more than about 0.0005%, about 0.001%, about 0.003%, about 0.0064%, about 0.0085%, about 0.01%, about 0.05%, about 0,1%, about 0.5%, about 1%, or about 2% (w / w) of a composition provided herein is (e.g., hydrolyzed) hyaluronic acid.

[0158] In some instances, the addition of hyaluronic acid to a composition provided herein is useful for smoothing or reducing frizz in the hair of an individual. In certain instances, addition of hyaluronic acid to a composition provided herein is useful for soothing skin on the scalp of an individual [0159J    In some aspects, compositions (e.g., a composition provided herein) comprise a rheology modifying agent. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise a rheology modifying agent. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one rheology modifying agent, two rheology modifying agents, three rheology modifying agents, four rheology modifying agents, five rheology modifying agents, or more. In certain embodiments, a rheology modifying agent (e.g., a rheology modifying agent provided herein) is useful for providing a stable suspension of a composition (e.g., a composition provided herein, such as a non-aerosol formulation). In certain instances, a rheology modifying agent is used as a emulsifying agent or gelling agent (e.g., such as by keeping oil and water phases together through fluctuations in temperature). In certain instances, addition of a rheology modifying agent to a composition (e.g,, a non-aerosol formulation) is useful for forming oil-in-water emulsions.

[0160] In some embodiments, a rheology modifying agent (e.g., a rheology modifying agent provided herein) comprises any suitable rheology modifying agent (such as a hydrocolloid). In some embodiments a rheology modifying agent comprises a naturally derived polymer. In certain embodiments, a rheology modifying agent comprises a hydrocolloid (e.g., gellan gum), aqueous natural polymer (e.g,, carboxymethyl cellulose), sugar (e.g., pectin), and the like. In certain embodiments, a rheology modifying agent comprises pectin, gellan gum, carrageen, glycerin, agar, xanthan gum, pullulan, algin, tetragonoloba (guar) gum, sclerotium gum, acacia Senegal gum, cellulose, cellulose gum, carboxymethylcellulose, carbomer, hydroxypropyl starch phosphate, guar hydroxypropyltrimonium chloride, carboxymethyl hydroxyethyl cellulose, carboxymethyl hydroxypropyl guar, cellulose, ethyl cellulose, hydroxybutyl methylcellulose, hydroxyethylcellulose, hydroxy methylcellulose, lauryl poly glucose, or a combination of two or more thereof. In specific embodiments, a rheology modifying agent in a composition (e.g., a composition provided herein) comprises agar. In yet more specific embodiments, a rheology modifying agent in a composition (e.g., a composition provided herein) comprises gellan gum. In still more specific embodiments, a rheology modifying agent in a composition (e.g., a composition provided herein) comprises carboxymethyl cellulose.

[0161] In certain embodiments, a composition (e.g., a composition provided herein) comprises a rheology modifying agent (e.g., a rheology modifying agent provided herein). In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein is a rheology modifying agent (e.g., a rheology modifying agent provided herein). In some embodiments, about 0.01% to about 2% (w / w) of a composition provided herein is a rheology modifying agent (e.g., a rheology modifying agent provided herein). In certain embodiments, about 0.05% to about 0.5% (w / w) of a composition provided herein is a rheology modifying agent (e.g., a rheology modifying agent provided herein).

[0162] In certain embodiments, a composition (e.g., a composition provided herein) comprises a rheology modifying agent, such as gellan gum. In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein is gellan gum. In some embodiments, about 0.01% to about 2% (w / w) of a composition provided herein is gellan gum. In certain embodiments, about 0.05% to about 0.5% (w / w) of a composition provided herein is gellan gum. In specific embodiments, about 0.5% to about 5% (w / w) of a composition provided herein is gellan gum. In yet more specific embodiments, about 0.05% to about 0.15% (w / w) of a composition provided herein is gellan gum. In still more specific embodiments, about 1% to about 2% (w / w) of a composition provided herein is gellan gum. In yet more specific embodiments, about 0.1% of a composition provided herein is gellan gum. In still more specific embodiments, about ¢).06% (w / w) of a composition provided herein is gellan gum. In yet more specific embodiments, about 5% to about 7% (w / w) of a composition provided herein is gellan gum. In still more specific embodiments, about 0.3% (w / w) of a composition provided herein is gellan gum. In yet more specific embodiments, about 2% to about 3.5% (w / w) of a composition provided herein is gellan gum.

[0163] In some embodiments, a composition provided herein comprises gellan gum at about 0.01% to about 10% (w / w) of the composition. In some embodiments, about 0.01% to about 0.05%, about 0.01% to about 0.08%, about 0.01% to about 0,1%, about 0.01% to about 0.12%, about 0.01% to about 0.15%, about 0.01% to about 0.25%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.01% to about 10%, about 0.05% to about 0.08%, about 0.05% to about 0.1%, about 0.05% to about 0.12%, about 0.05% to about 0.15%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.05% to about 2.5%, about 0.05% to about 5%, about 0.05% to about 10%, about 0.08% to about 0.1%, about 0.08% to about 0.12%, about 0.08% to about 0.15%, about 0.08% to about 0.25%, about 0.08% to about 0,5%, about 0.08% to about 1%, about 0.08% to about 2.5%, about 0.08% to about 5%, about 0.08% to about 10%, about 0.1% to about 0.12%, about 0.1% to about 0.15%, about 0.1 % to about 0.25%, about 0.1 % to about 0.5%, about 0.1% to about 1 %, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.1% to about 10%, about 0.12% to about 0.15%, about 0.12% to about 0.25%, about 0.12% to about 0.5%, about 0.12% to about 1%, about 0.12% to about 2.5%, about 0.12% to about 5%, about 0.12% to about 10%, about 0.15% to about 0.25%, about 0.15% to about 0.5%, about 0.15% to about 1%, about 0.15% to about 2.5%, about 0.15% to about 5%, about 0.15% to about 10%, about 0.25% to about 0.5%, about 0.25% to about 1%, about 0.25% to about 2,5%, about 0.25% to about 5%, about 0.25% to about 10%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 0.5% to about 10%, about 1 % to about 2,5%, about 1% to about 5%, about 1% to about 10%, about 2,5% to about 5%, about 2.5% to about 10%, or about 5% to about 10% (w / w) of a composition provided herein is gellan gum. In some embodiments, about 0.01%, about 0.05%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is gellan gum. In some embodiments, at least about 0.01%, about 0.05%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of a composition provided herein is gellan gum. In some embodiments, not more than about 0,05%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is gellan gum.

[0164] In certain instances, the addition of gellan gum is useful for suspending components of a composition, such as a non-aerosol, hydroalcoholic formulation.

[0165] In some aspects, compositions (e.g., a composition provided herein) comprise a stabilizing agent. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise a stabilizing agent. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one stabilizing agent, two stabilizing agents, three stabilizing agents, four stabilizing agents, five stabilizing agents, or more. In certain embodiments, a stabilizing agent (e.g., a stabilizing agent provided herein) is useful for maintaining the function and activity of additional agents of a composition (e.g., a composition provided herein, such as a nonaerosol formulation). In some embodiments, when a rheology modifier is present, the rheology modifier creates a shear-thinning structure gel that suspends powders and prevents compaction. In some embodiments, the shear-thinning structure gel sets and is maintained by the cations of the stabilizing agent, such as NaCl or MgCh.

[0166] In some embodiments, a stabilizing agent comprises a salt, sulfate, or the like. In some embodiments, a stabilizing agent comprises calcium chloride, magnesium chloride, magnesium sulfate, potassium chloride, potassium glycol sulfate, sodium chloride, or a combination of two or more thereof. In specific embodiments, a stabilizing agent in a composition (e.g., a composition provided herein) comprises calcium chloride. In yet more specific embodiments, a stabilizing agent in a composition (e.g., a composition provided herein) comprises sodium chloride. In still more specific embodiments, a stabilizing agent in a composition (e.g., a composition provided herein) comprises potassium glycol sulfate.

[0167] In certain embodiments, a composition (e.g., a composition provided herein) comprises a stabilizing agent (e.g., a stabilizing agent provided herein). In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein is a stabilizing agent (e.g,, a stabilizing agent provided herein). In some embodiments, about 0.01% to about 2% (w / w) of a composition provided herein is a stabilizing agent (e.g., a stabilizing agent provided herein). In certain embodiments, about 0.05% to about 0.5% (w / w) of a composition provided herein is a stabilizing agent (e.g., a stabilizing agent provided herein).

[0168] In certain embodiments, a composition (e.g., a composition provided herein) comprises a stabilizing agent, such as sodium chloride. In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein is sodium chloride. In some embodiments, about 0.01% to about 2% (w / w) of a composition provided herein is sodium chloride. In certain embodiments, about 0.05% to about 0.5% (w / w) of a composition provided herein is sodium chloride. In specific embodiments, about 0.5% to about 5% (w / w) of a composition provided herein is sodium chloride. In yet more specific embodiments, about 0.05% to about 0.15% (w / w) of a composition provided herein is sodium chloride. In still more specific embodiments, about 1% to about 2% (w / w) of a composition provided herein is sodium chloride. In yet more specific embodiments, about 0.1% of a composition provided herein is sodium chloride. In still more specific embodiments, about 0.06% (wAv) of a composition provided herein is sodium chloride. In yet more specific embodiments, about 5% to about 7% (wAv) of a composition provided herein is sodium chloride. In still more specific embodiments, about 0.3% (w / w) of a composition provided herein is sodium chloride. In yet more specific embodiments, about 2% to about 3.5% (w / w) of a composition provided herein is sodium chloride.

[0169] In some embodiments, a composition provided herein comprises sodium chloride at about 0.001% to about 10% of tire composition. In some embodiments, about 0.001% to about 0.01%, about 0.001% to about 0.08%, about 0.001% to about 0.1%, about 0.001% to about 0.12%, about 0.001% to about 0.15%, about 0.001% to about 0.25%, about 0.001% to about 0,5%, about 0.001% to about 1%, about 0.001% to about 2.5%, about 0.001% to about 5%, about 0.001% to about 10%, about 0.01% to about 0.08%, about 0.01% to about 0.1%, about 0.01% to about 0.12%, about 0.01% to about ¢). 15%, about 0.01% to about 0.25%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01 % to about 5%, about 0.01% to about 10%, about 0.08% to about 0.1%, about 0.08% to about 0.12%, about 0.08% to about 0.15%, about 0.08% to about 0.25%, about 0.08% to about 0.5%, about 0.08% to about 1%, about 0.08% to about 2.5%, about 0.08% to about 5%, about 0.08% to about 10%, about 0,1% to about 0.12%, about 0.1% to about 0.15%, about 0.1% to about 0.25%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.1% to about 10%, about 0.12% to about 0.15%, about 0.12% to about 0.25%, about 0.12% to about 0.5%, about 0.12% to about 1%, about 0.12% to about 2.5%, about 0.12% to about 5%, about 0.12% to about 10%, about 0.15% to about 0.25%, about 0.15% to about 0.5%, about 0.15% to about 1%, about 0.15% to about 2.5%, about 0.15% to about 5%, about 0.15% to about 10%, about 0.25% to about 0.5%, about 0.25% to about 1%, about 0.25% to about 2.5%, about 0.25% to about 5%, about 0.25% to about 10%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 0.5% to about 10%, about 1% to about 2.5%, about 1% to about 5%, about 1% to about 10%, about 2.5% to about 5%, about 2.5% to about 10%, or about 5% to about 10% (w / w) of a composition provided herein is sodium chloride. In some embodiments, about 0.001%, about 0.01%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is sodium chloride. In some embodiments, at least about 0.001%, about 0.01%, about 0.08%, about 0.1%, about 0.12%, about 0,15%, about 0.25%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of a composition provided herein is sodium chloride. In some embodiments, not more than about 0.01%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is sodium chloride.

[0170] In some aspects, compositions (e.g., a composition provided herein) comprise a chelating agent. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise a chelating agent. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one chelating agent, two chelating agents, three chelating agents, four chelating agents, five chelating agents, or more. In certain instances, a chelating agent (e.g., a chelating agent provided herein) is useful for binding to metals and preventing metal-catalyzed reactions in a composition (e.g., a composition provided herein, such as a non-aerosol formulation) thereby stabilizing such compositions. In certain instances, chelating agents are useful for removing mineral deposits and impurities (such as from the scalp and / or hair of an individual). [0171 ]     In certain embodiments, a chelating agent can be any suitable chelating agent (e.g., .EDTA, sodium phytate, and the like). In some embodiments, a chelating agent comprises EDTA, sodium phytate, sodium gluconate, trisodium dicarboxymethyl alaninate, tetrasodium glutamate diacetate, caprylhydroxamic acid, or a combination of two or more thereof. In specific embodiments, a chelating agent in a composition (e.g., a composition provided herein) comprises EDTA. In yet more specific embodiments, a chelating agent in a composition (e.g., a composition provided herein) comprises sodium phytate. In still more specific embodiments, a chelating agent in a composition (e.g., a composition provided herein) comprises sodium gluconate.

[0172] In certain embodiments, a composition (e.g., a composition provided herein) comprises a chelating agent (e.g., a chelating agent provided herein). In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein is a chelating agent (e.g., a chelating agent provided herein). In some embodiments, about 0.01 % to about 2% (w / w) of a composition provided herein is a chelating agent (e.g., a chelating agent provided herein). In certain embodiments, about 0.05% to about 0.5% (w / w) of a composition provided herein is a chelating agent (e.g., a chelating agent provided herein).

[0173] In certain embodiments, a composition (e.g., a composition provided herein) comprises a chelating agent, such as sodium phytate. In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein is sodium phytate. In some embodiments, about 0.01% to about 2% (w / w) of a composition provided herein is sodium phytate. In certain embodiments, about 0.05% to about 0.5% (w / w) of a composition provided herein is sodium phytate. In specific embodiments, about 0.5% to about 5% (w / w) of a composition provided herein is sodium phy tate. In yet more specific embodiments, about 0.05% to about 0.15% (w / w) of a composition provided herein is sodium phytate. In still more specific embodiments, about 1% to about 2% (w / 'w) of a composition provided herein is sodium phy tate. In yet more specific embodiments, about 0.1% of a composition provided herein is sodium phytate. In still more specific embodiments, about 0.06% (w / w) of a composition provided herein is sodium phytate. In yet more specific embodiments, about 5% to about 7% (w7w) of a composition provided herein is sodium phytate. In still more specific embodiments, about 0.3% (w / w) of a composition provided herein is sodium phytate. In yet more specific embodiments, about 2% to about 3.5% (w / w) of a composition provided herein is sodium phytate.

[0174] In some embodiments, a composition provided herein comprises sodium phytate at about ¢).01% to about 10% (w / w) of the composition. In some embodiments, about 0.01% to about 0.05%, about 0.01% to about 0.08%, about 0.01% to about 0.1%, about 0.01% to about 0.12%, about 0.01% to about 0.15%, about 0.01% to about 0.25%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.01% to about 10%, about 0.05% to about 0.08%, about 0.05% to about 0.1%, about 0.05% to about 0.12%, about 0.05% to about 0.15%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.05% to about 2.5%, about 0,05% to about 5%, about 0,05% to about 10%, about 0.08% to about 0.1%, about 0.08% to about 0.12%, about 0.08% to about 0.15%, about 0.08% to about 0.25%, about 0.08% to about 0,5%, about 0.08% to about 1%, about 0.08% to about 2.5%, about 0.08% to about 5%, about 0.08% to about 10%, about 0.1% to about 0.12%, about 0.1% to about 0.15%, about 0.1 % to about 0.25%, about 0.1 % to about 0.5%, about 0.1% to about 1 %, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0.1% to about 10%, about 0.12% to about 0.15%, about 0.12% to about 0.25%, about 0.12% to about 0.5%, about 0.12% to about 1%, about 0.12% to about 2.5%, about 0.12% to about 5%, about 0.12% to about 10%, about 0.15% to about 0.25%, about 0,15% to about 0.5%, about 0.15% to about 1%, about 0.15% to about 2.5%, about 0.15% to about 5%, about 0.15% to about 10%, about 0.25% to about 0.5%, about 0.25% to about 1%, about 0.25% to about 2.5%, about 0.25% to about 5%, about 0.25% to about 10%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 0.5% to about 10%, about 1% to about 2.5%, about 1% to about 5%, about 1% to about 10%, about 2.5% to about 5%, about 2.5% to about 10%, or about 5% to about 10% (w / w) of a composition provided herein is sodium phytate. In some embodiments, about0.01%, about0.05%, about 0.08%, about0.1%, about 0.12%, about0.15%, aboutO.25%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is sodium phytate. In some embodiments, at least about 0.01%, about 0.05%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of a composition provided herein is sodium phytate. In some embodiments, not more than about 0.05%, about 0.08%, about 0.1%, about 0.12%, about 0.15%, about 0.25%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is sodium phytate.

[0175] In some aspects, compositions (e.g., a composition provided herein) comprise a preservative. In specific embodiments, additional agents of compositions (e.g,, a composition provided herein) comprise a preservative. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one preservative, two preservatives, three preservatives, four preservatives, five preservatives, or more. In some instances, preservatives (e.g., a preservative provided herein) are useful for extending the duration of efficacy of (e.g., active components, such as an odor binding protein provided herein) of a composition (e.g., a composition provided herein, such as a non-aerosol formulation). In certain instances, addition of preservatives to a composition provided herein (e.g., anon-aerosol, hydroalcoholic formulation) are useful for inhibiting and / or preventing growth of harmful microorganisms in such compositions.

[0176] In some embodiments, a preservative (e.g., a preservative provided herein) can be any suitable preservative (e.g., used in products fit for human consumption, such as personal care products). In some embodiments, a preservative comprises a alcohol (e.g., benzyl alcohol), paraben, formaldehyde release, carbamate, sorbate, and the like. In certain embodiments, a preservative comprises benzyl alcohol, benzoic acid, butyl paraben, diazolidmyl urea, DMDM hydantoin, ethyl paraben, imidazolidinyl urea, iodopropynyl butylcarbamate, isobutyl paraben, methyl paraben, metbyichloroisothiazohnone, methyhsothiazoiinone, phenoxyethanol, propyl paraben, sodium benzoate, potassium sorbate, ethylhexylglycerin, gluconolactone, or a combination of two or more thereof. In specific embodiments, a preservative in a composition (e.g., a composition provided herein) comprises potassium sorbate. In yet more specific embodiments, a preservative in a composition (e.g., a composition provided herein) comprises benzyl alcohol. In still more specific embodiments, a preservative in a composition (e.g., a composition provided herein) comprises phenoxyethanol.

[0177] In certain embodiments, about 0.005% to about 10% (w / w) of a composition provided herein comprises a preservative (e.g., a preservative provided herein). In some embodiments, about .01% to about 5% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In certain embodiments, about 0.5% to about 2% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In specific embodiments, about 0.8% to about 1.2% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In yet more specific embodiments, about 0.9% to about 1.1% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In still more specific embodiments, about 0.95% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In yet more specific embodiments, about 1.5% to about 7.5% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In still more specific embodiments, about 2% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In specific embodiments, the preservative is benzyl alcohol.

[0178] In some embodiments, a composition provided herein comprises a preservative (e.g., a preservative provided herein) at about 0.01% to about 10% (w / w) of the composition. In some embodiments, about 0.01% to about 0.05%, about 0.01% to about 0.1%, about 0.01% to about 0.2%, about 0.01% to about 0.4%, about 0.01% to about 0.7%, about 0.01% to about 0.95%, about 0.01% to about 1.1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.01% to about 7.5%, about 0.01% to about 10%, about 0.05% to about 0.1%, about 0.05% to about 0.2%, about 0.05% to about 0.4%, about 0.05% to about 0.7%, about 0.05% to about 0,95%, about 0.05% to about 1.1%, about 0.05% to about 2.5%, about 0.05% to about 5%, about 0.05% to about 7.5%, about 0.05% to about 10%, about 0.1 % to about 0,2%, about 0.1% to about 0.4%, about 0.1% to about 0.7%, about 0.1% to about 0.95%, about ¢).1% to about 1.1%, about 0.1% to about 2.5%, about 0.1% to about 5%, about 0,1% to about 7.5%, about 0.1% to about 10%, about 0.2% to about 0.4%, about 0.2% to about 0.7%, about 0.2% to about 0.95%, about 0.2% to about 1.1%, about 0.2% to about 2.5%, about 0.2% to about 5%, about 0.2% to about 7.5%, about 0.2% to about 10%, about 0.4% to about 0.7%, about 0.4% to about 0.95%, about 0.4% to about 1.1%, about 0.4% to about 2.5%, about 0.4% to about 5%, about 0.4% to about 7.5%, about ¢).4% to about 10’%, about 0.7% to about 0.95%, about 0.7% to about 1.1%, about 0,7% to about 2.5%, about 0.7% to about 5%, about 0.7% to about 7.5%, about 0.7% to about 10%, about 0.95% to about 1.1%, about ¢).95% to about 2.5%, about 0.95% to about 5%, about 0.95% to about 7.5%, about 0.95% to about 10%, about 1.1% to about 2.5%, about 1.1% to about 5%, about 1.1% to about 7.5%, about 1.1% to about 10%, about 2.5’% to about 5%, about 2.5% to about 7.5’%, about 2.5% to about 10’%, about 5% to about 7.5%, about 5% to about 10%, or about 7.5% to about 10% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In some embodiments, about 0.01%, about 0.05%, about 0.1%, about 0.2%, about 0.4%, about 0.7%, about 0.95%, about 1.1%, about 2.5%, about 5%, about 7.5%, or about 10% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In some embodiments, at least about 0.01%, about 0.05%, about 0.1%, about 0.2%, about 0.4%, about 0.7%, about 0.95%, about 1.1%, about 2.5%, about 5%, or about 7.5% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein). In some embodiments, not more than about 0.05%, about 0.1%, about 0.2%, about 0.4%, about 0.7%, about 0.95%, about 1.1%, about 2.5%, about 5%, about 7.5%, or about 10% (w / w) of a composition provided herein is a preservative (e.g., a preservative provided herein).

[0179] In some aspects, compositions (e.g., a composition provided herein) comprise a fragrance component. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise a fragrance component. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one fragrance component, two fragrance components, three fragrance components, four fragrance components, five fragrance components, or more. In some instances, fragrance components (e.g., a fragrance component provided herein) are provided in a composition (e.g., a composition provided herein, such as a nonaerosol, hydroalcoholic formulation) to reduce malodor (e.g., of the scalp and hair of an individual). In certain instances, fragrance components are useful additions to compositions provided herein for reduction of malodor (e.g., of an individual)). In some instances, fragrance components of compositions provided herein provide pleasant odors to such compositions.

[0180] In some embodiments, a fragrance component can be any suitable fragrance (e.g., used in personal hygiene products of an individual). In some embodiments, a fragrance component comprises a synthetic or naturally derived fragrance. In certain embodiments, a fragrance component (e.g., a fragrance component provided herein) comprises linalool, hexyl cinnamal, limonene, or benzyl alcohol, and the like. In some embodiments, a fragrance component (e.g., a fragrance component provided herein) comprises linalool, hexyl cinnamal, limonene, or benzyl alcohol, and / or a combination of two or more thereof.

[0181] In certain embodiments, about 0.01% to about 10% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In some embodiments, about 0.05% to about 5% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In certain embodiments, about 0.1% to about 1% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In specific embodiments, about 0.2% to about 0.3% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In yet more specific embodiments, about 0.25% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In still more specific embodiments, about 0.1% to about 0.3% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In specific embodiments, the fragrance component comprises linalool, hexyl cinnamal, limonene, or benzyl alcohol, or a combination of two or more thereof.

[0182] In some embodiments, a composition provided herein comprises a fragrance component (e.g., a fragrance component provided herein) at about 0.01% to about 10% (w / w) of the composition. In some embodiments, about 0.01% to about 0.05%, about 0.01% to about 0.08%, about 0.01% to about 0.1%, about 0.01% to about 0.2%, about 0.01% to about 0.25%, about 0.01% to about 0.3%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.01% to about 2.5%, about 0.01% to about 5%, about 0.01% to about 10%, about 0.05% to about 0.08%, about 0.05% to about 0.1%, about 0.05% to about 0.2%, about 0.05% to about 0.25%, about 0.05% to about 0.3%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.05% to about 2.5%, about 0.05% to about 5%, about 0.05% to about 10%, about 0.08% to about 0.1%, about 0.08% to about 0.2%, about 0.08% to about 0.25%, about 0.08% to about 0.3%, about 0.08% to about 0.5%, about 0.08% to about 1%, about 0.08% to about 2.5%, about 0.08% to about 5%, about 0.08% to about 10%, about 0.1% to about 0.2%, about 0.1% to about 0.25%, about 0,1 % to about 0.3%, about 0.1% to about 0.5%, about ¢). 1% to about 1%, about 0.1 % to about 2.5%, about 0.1% to about 5%, about 0.1% to about 10%, about 0,2% to about 0.25%, about 0.2% to about 0,3%, about 0.2% to about 0.5%, about 0.2% to about 1%, about 0.2% to about 2.5%, about 0.2% to about 5%, about 0.2% to about 10%, about 0.25% to about 0,3%, about 0.25% to about 0.5%, about 0.25% to about 1%, about 0.25% to about 2.5%, about 0.25% to about 5%, about 0.25% to about 10%, about 0.3% to about 0.5%, about 0.3% to about 1%, about 0.3% to about 2.5%, about 0.3% to about 5%, about 0.3% to about 10%, about 0.5% to about 1%, about 0.5% to about 2.5%, about 0.5% to about 5%, about 0.5% to about 10%, about 1% to about 2.5%, about 1% to about 5%, about 1% to about 10%, about 2.5% to about 5%, about 2.5% to about 10%, or about 5% to about 10% (wAv) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In some embodiments, about 0.01%, about 0.05%, about 0,08%, about 0.1%, about 0.2%, about 0.25%, about 0.3%, about 0,5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is a fragrance component, (e.g., a fragrance component provided herein). In some embodiments, at least about 0.01%, about 0.05%, about 0.08%, about 0.1%, about 0.2%, about 0.25%, about 0.3%, about 0.5%, about 1%, about 2.5%, or about 5% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In some embodiments, not more than about 0.05%, about 0.08%, about 0.1%, about 0.2%, about 0.25%, about 0.3%, about 0.5%, about 1%, about 2.5%, about 5%, or about 10% (w / w) of a composition provided herein is a fragrance component (e.g., a fragrance component provided herein). In specific embodiments, the fragrance component comprises linalool, hexyl cinnamal, limonene, or benzyl alcohol, or a combination of two or more thereof.

[0183] In some aspects, compositions (e.g., a composition provided herein) comprise a buffering agent. In specific embodiments, additional agents of compositions (e.g., a composition provided herein) comprise a buffering agent. In yet more specific embodiments, compositions (e.g., a composition provided herein) comprise one buffering agent, two buffering agents, three buffering agents, four buffering agents, five buffering agents, or more. In some instances, buffering agents (e.g., a buffering agent provided herein) are provided in a composition (e.g., a composition provided herein, such as a non-aerosol, hydroalcoholic formulation) to raise or lower the pH of such composition (or for raising or lowering pH of the scalp or hair of an individual). In certain instances, buffering agents maintain the pH of compositions provided herein.

[0184] In some embodiments, the buffering agent can be any acid or base suitable for use in products fit for human consumption, such as personal care products. In certain embodiments, a buffering agent (e.g., a buffering agent provided herein) comprises weak acids, weak bases, amino acids, weak organic acids, weak organic bases, and the like. In some embodiments, buffering agents (e.g., a buffering agent provided herein) can comprise citric acid, lactic acid, glycolic acid, malic acid, tartaric acid, arginine, tromethamine, sodium hydroxide, potassium hydroxide, or a combination of two or more thereof. In specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) lactic acid. In yet more specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) comprises citric acid. In still more specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) comprises tromethamine. In yet more specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) comprises arginine. In still more specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) comprises malic acid.

[0185] In certain embodiments, a buffering agent (e.g., total buffering agent) is about 0.001% to about 1% by weight (w / w) of a composition (e.g., a composition provided herein). In some embodiments, a buffering agent is about 0.005% to about 0.5% (w / w) of the composition. In certain embodiments, a buffering agent is about 0.01% to about 0.1% (w / w) of the composition.

[0186] In certain embodiments, about 0.0005% to about 1% (w / w) of a composition provided herein comprises a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about 0.0001% to about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In certain embodiments, about 0.0005% to about 0.01% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In specific embodiments, about 0.001% to about 0.002% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In yet more specific embodiments, about 0.0017% to about 0.0019% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.0018% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In yet more specific embodiments, about 0.0005% to about 0.0009% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) comprises lactic acid.

[0187] In some embodiments, a composition provided herein comprises a buffering agent (e.g., a buffering agent provided herein) at about 0.0001% to about 1% (w / w) of the composition. In some embodiments, about 0.0001% to about 0.0003%, about 0.0001% to about 0.0006%, about 0.0001% to about 0.0009%, about 0.0001% to about 0.0012%, about 0.0001% to about 0.0018%, about 0.0001% to about 0.0025%, about 0.0001% to about 0.05%, about 0.0001% to about 0.1%, about 0.0001% to about 0.25%, about 0.0001% to about 0.5%, about 0.0001% to about 1%, about 0.0003% to about 0.0006%, about 0.0003% to about 0.0009%, about 0.0003% to about 0.0012%, about 0.0003% to about 0.0018%, about 0.0003% to about 0.0025%, about 0.0003% to about 0.05%, about 0.0003% to about 0.1%, about 0.0003% to about 0.25%, about 0.0003% to about 0.5%, about 0.0003% to about 1%, about 0.0006% to about 0.0009%, about 0.0006% to about 0.0012%, about 0.0006% to about 0.0018%, about 0.0006% to about 0.0025%, about 0.0006% to about 0.05%, about 0.0006% to about 0.1%, about 0.0006% to about 0.25%, about 0.0006% to about 0.5%, about 0.0006% to about 1%, about 0.0009% to about 0.0012%, about 0.0009% to about 0.0018%, about 0.0009% to about 0.0025%, about 0.0009% to about 0.05%, about 0.0009% to about 0.1%, about 0.0009% to about 0.25%, about 0.0009% to about 0.5%, about 0.0009% to about 1%, about 0.0012% to about 0.0018%, about 0,0012% to about 0.0025%, about 0.0012% to about 0.05%, about 0,0012% to about 0.1%, about 0.0012% to about 0.25%, about 0.0012% to about 0.5%, about 0.0012% to about 1%, about 0,0018% to about 0.0025%, about 0.0018% to about 0.05%, about 0.0018% to about 0.1%, about 0.0018% to about 0.25%, about 0.0018% to about 0.5%, about 0.0018% to about 1%, about 0.0025% to about 0.05%, about 0.0025% to about 0.1%, about 0.0025% to about 0.25%, about 0.0025% to about 0.5%, about 0.0025% to about 1%, about 0.05% to about 0.1%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 1%, about 0.1% to about 0.25%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.25% to about 0.5%, about 0.25% to about 1%, or about 0.5% to about 1% (w' / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about 0.0001%, about 0.0003%, about 0.0006%, about 0.0009%, about 0.0012%, about 0.0018%, about 0.0025%, about 0.05%, about 0.1%, about 0.2.5%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, at least about 0.0001%, about 0.0003%, about 0.0006%, about 0.0009%, about 0.0012%, about 0.0018%, about 0.002.5%, about 0.05%, about 0.1%, about 0.2.5%, or about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, not more than about 0.0003%, about 0.0006%, about 0.0009%, about 0.0012%, about 0.0018%, about 0.0025%, about 0.05%, about 0.1%, about 0.25%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein).

[0188] In certain embodiments, about 0.001% to about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about 0.005% to about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In certain embodiments, about. 0.01% to about 0.1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In specific embodiments, about 0.04% to about 0.06% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In yet more specific embodiments, about 0.045% to about 0.055% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.0515% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In yet more specific embodiments, about 0.0005% to about 0.0007% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.1% (w / w) of a composition provided herein is a buffering agent, (e.g,, a buffering agent provided herein). In specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) citric acid.

[0189] In some embodiments, a composition provided herein comprises a buffering agent (e.g., a buffering agent provided herein) at about 0,0001% to about 1% (w / w) of the composition. In some embodiments, about 0.0001% to about 0.0003%, about 0.0001% to about 0.0006%, about 0.0001% to about. 0.0009%, about 0,0001% to about 0.0012%, about 0.0001% to about 0.0018%, about 0.0001% to about 0.0025%, about 0.0001% to about 0.0515%, about 0.0001% to about 0.1%, about 0.0001% to about 0.25%, about 0.0001% to about 0,5%, about 0.0001% to about 1%, about 0,0003% to about 0.0006%, about 0.0003% to about 0.0009%, about 0.0003% to about 0.0012%, about 0.0003% to about 0.0018%, about 0.0003% to about. 0.0025%, about 0.0003% to about 0.0515%, about 0.0003% to about 0.1%, about 0.0003% to about 0.25%, about 0.0003% to about 0.5%, about 0.0003% to about 1%, about 0.0006% to about 0.0009%, about 0.0006% to about 0.0012%, about 0.0006% to about 0.0018%, about 0.0006% to about 0,0025%, about 0.0006% to about 0.0515%, about 0.0006% to about 0.1%, about 0.0006% to about 0.25%, about 0.0006% to about 0.5%, about 0.0006% to about 1%, about 0.0009% to about 0.0012%, about 0.0009% to about. 0.0018%, about 0.0009% to about 0.0025%, about 0.0009% to about 0.0515%, about 0.0009% to about 0.1%, about 0.0009% to about 0.25%, about 0.0009% to about 0.5%, about. 0.0009% to about 1%, about 0.0012% to about 0.0018%, about 0.0012% to about 0.0025%, about 0.0012% to about 0.0515%, about 0.0012% to about 0.1%, about 0.0012% to about 0.25%, about 0.0012% to about 0.5%, about 0.0012% to about 1%, about 0.0018% to about 0.0025%, about 0.0018% to about 0.0515%, about 0.0018% to about 0.1%, about 0.0018% to about 0.25%, about 0.0018% to about 0.5%, about 0.0018% to about 1%, about 0.0025% to about 0.0515%, about 0.0025% to about 0.1%, about 0.0025% to about 0.25%, about 0.0025% to about 0.5%, about 0.0025% to about 1%, about 0.0515% to about 0.1%, about 0.0515% to about 0.25%, about 0.0515% to about 0.5%, about 0.0515% to about 1%, about 0.1% to about 0.25%, about 0.1% to about 0.5%, about 0.1% to about 1%, about 0.25% to about 0.5%, about 0.25% to about 1%, or about 0.5% to about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about 0.0001%, about 0.0003%, about 0.0006%, about 0.0009%, about 0.0012%, about 0.0018%, about 0.0025%, about 0.0515%, about 0.1%, about 0.25%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, at least about 0.0001%, about 0.0003%, about 0.0006%, about 0.0009%, about 0.0012%, about 0.0018%, about 0.0025%, about 0.0515%, about 0.1%, about 0.25%, or about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, not more than about 0.0003%, about 0.0006%, about 0.0009%, about 0.0012%, about 0.0018%, about 0.0025%, about 0.0515%, about 0.1%, about 0.25%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein).

[0190] In certain embodiments, about 0.0001% to about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, tire buffering agent comprises tromethamine, or Tris. In some embodiments, about 0.0005% to about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In certain embodiments, about 0.001% to about 0.05% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). [0191 [ In specific embodiments, about 0.003% to about 0.005% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.004% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In yet more specific embodiments, about 0.0001% to about 0.0003% (w / wj of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.6% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In specific embodiments, the buffering agent in a composition (e.g., a composition provided herein) comprises tromethamine.

[0192] In some embodiments, a composition provided herein comprises a buffering agent (e.g., a buffering agent provided herein) at about 0.0001% to about 1% of the composition. In some embodiments, about 0.0001% to about 0.0003%, about 0.0001% to about 0.0009%, about 0.0001% to about 0.0025%, about 0,0001% to about 0.004%, about 0.0001% to about 0.006%, about 0,0001% to about 0.01%, about 0.0001% to about 0.05%, about ¢).0001% to about 0.1%, about 0.0001% to about 0.25%, about 0.0001% to about 0.5%, about 0.0001% to about 1%, about 0.0003% to about 0.0009%, about 0.0003% to about 0.0025%, about 0.0003% to about 0.004%, about 0.0003% to about 0.006%, about 0.0003% to about 0.01%, about 0.0003% to about 0.05%, about 0.0003% to about 0.1%, about 0.0003% to about 0.25%, about 0.0003% to about 0.5%, about 0.0003% to about 1%, about 0.0009% to about 0.0025%, about 0.0009% to about 0.004%, about 0.0009% to about 0.006%, about 0.0009% to about 0.01%, about 0.0009% to about 0.05%, about 0.0009% to about 0.1%, about ¢).0009% to about 0.25%, about 0.0009% to about 0.5%, about 0.0009% to about 1%, about 0.0025% to about 0.004%, about 0.0025% to about 0.006%, about 0.0025% to about 0.01%, about 0.0025% to about 0.05%, about 0.0025% to about 0.1%, about 0.0025% to about 0.25%, about 0.0025% to about 0.5%, about 0.0025% to about 1%, about 0.004% to about 0.006%, about 0.004% to about 0.01%, about 0.004% to about 0.05%, about 0.004% to about 0.1%, about 0.004% to about 0.25%, about 0.004% to about 0.5%, about 0.004% to about 1%, about 0.006% to about 0.01%, about 0.006% to about 0.05%, about 0.006% to about 0.1%, about 0.006% to about 0.25%, about 0.006% to about 0.5%, about 0.006% to about 1%, about 0.01% to about 0.05%, about 0.01% to about 0.1%, about 0.01% to about 0,2.5%, about 0.01% to about 0,5%, about 0.01% to about 1%, about 0.05% to about 0.1%, about 0.05% to about 0.25%, about 0.05% to about 0.5%, about 0.05% to about 1 %, about 0.1% to about 0.25%, about 0.1% to about 0.5%, about 0.1 % to about 1%, about 0.25% to about 0.5%, about 0.25% to about 1%, or about 0.5% to about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about 0.0001%, about 0.0003%, about 0.0009%, about 0.0025%, about 0.004%, about 0.006%, about 0.01%, about 0.05%, about 0.1%, about 0.25%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g,, a buffering agent provided herein). In some embodiments, at least about 0.0001%, about 0.0003%, about 0.0009%, about 0.0025%, about 0.004%, about 0.006%, about 0.01%, about 0,05%, about 0.1%, about 0.25%, or about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, not more than about 0.0003%, about 0.0009%, about 0.0025%, about 0.004%, about 0.006%, about 0.01%, about 0.05%, about 0.1%, about 0.25%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein).

[0193] In certain embodiments, about 0.00001% to about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about ¢).00()05% to about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In certain embodiments, about 0.000075% to about 0.005% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In specific embodiments, about 0.00009% to about 0.00011% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.0001 % (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In yet more specific embodiments, about 0.0005% to about 0.001% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In still more specific embodiments, about 0.2% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In specific embodiments, a buffering agent in a composition (e.g., a composition provided herein) is arginine.

[0194] In some embodiments, a composition provided herein comprises a buffering agent (e.g., a buffering agent provided herein) at about 0.00001% to about 1% (w / w) of a total weight of the composition. In some embodiments, about 0.00001% to about 0.00002%, about 0.00001% to about 0.00004%, about 0.00001% to about 0.00006%, about 0.00001% to about 0.00008%, about 0.00001% to about 0.0001%, about 0.00001% to about 0.0005%, about 0.00001% to about 0.001%, about 0.00001% to about 0.01%, about 0.00001% to about 0.1%, about 0.00001% to about 0.5%, about 0.00001% to about 1%, about 0.00002% to about 0.00004%, about 0.00002% to about 0.00006%, about 0.00002% to about 0.00008%, about 0.00002% to about 0.0001%, about 0.00002% to about 0.0005%, about 0,00002% to about 0.001%, about 0.00002% to about 0.01%, about 0.00002% to about 0.1%, about 0.00002% to about 0.5%, about 0.00002% to about 1%, about 0.00004% to about 0.00006%, about 0.00004% to about 0,00008%, about 0.00004% to about 0.0001%, about 0.00004% to about 0.0005%, about 0.00004% to about 0.001%, about 0.00004% to about 0.01%, about 0.00004% to about 0.1%, about 0.00004% to about 0.5%, about 0.00004% to about 1%, about 0.00006% to about 0.00008%, about 0.00006% to about 0.0001%, about 0.00006% to about 0.0005%, about 0.00006% to about 0.001%, about 0.00006% to about 0.01%, about 0.00006% to about 0.1%, about 0,00006% to about 0.5%, about 0.00006% to about 1%, about 0.00008% to about 0.0001%, about 0.00008% to about 0.0005%, about 0.00008% to about 0.001%, about 0.00008% to about 0.01%, about 0.00008% to about 0.1%, about 0.00008% to about 0,5%, about 0.00008% to about 1%, about 0.0001% to about 0.0005%, about 0.0001% to about 0.001%, about 0.0001% to about 0.01%, about 0.0001% to about 0.1%, about 0.0001% to about 0.5%, about 0.0001% to about 1%, about 0.0005% to about 0.001%, about 0.0005% to about 0.01%, about 0.0005% to about 0.1%, about 0.0005% to about 0.5%, about 0.0005% to about 1%, about 0.001% to about 0.01%, about 0.001% to about 0.1%, about 0.001% to about 0.5%, about 0.001% to about 1%, about 0.01% to about 0.1%, about 0.01% to about 0.5%, about 0.01% to about 1%, about 0.1% to about 0.5%, about 0.1% to about 1%, or about 0.5% to about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, about 0.00001%, about 0.00002%, about 0,00004%, about 0.00006%, about 0.00008%, about 0.0001%, about 0.0005%, about 0.001%, about 0.01%, about 0.1%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, at least about 0.00001%, about 0.00002%, about 0.00004%, about 0,00006%, about 0.00008%, about 0.0001%, about 0.0005%, about 0.001%, about 0.01%, about 0.1%, or about 0.5% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein). In some embodiments, not more than about 0.00002%, about 0.00004%, about 0.00006%, about 0.00008%, about 0.0001%, about 0.0005%, about 0.001%, about 0.01%, about 0.1’%, about 0.5%, or about 1% (w / w) of a composition provided herein is a buffering agent (e.g., a buffering agent provided herein).

[0195] In certain embodiments, a composition (e.g., a composition provided herein) comprises an odor binding protein and an absorbing agent. In specific embodiments, the composition comprises an odor binding protein, an absorbing agent, and one or more of: a solvent, humectant, rheology modifying agent, chelating agent, sebum regulating agent, fragrance component, buffering agent. In yet more specific embodiments, the composition comprises an odor binding protein, absorbing agent, humectant, rheology modifying agent, chelating agent, sebum regulating agent, fragrance component, buffering agent, and solvent. In still more specific embodiments, the composition comprises an odor binding protein, absorbing agent, sebum regulating agent, buffering agent, and solvent. In yet more specific embodiments, the composition comprises an odor binding protein, absorbing agent, humectant, rheology modifying agent, buffering agent, and solvent. In still more specific embodiments, the composition comprises an odor binding protein, absorbing agent, rheology modifying agent, chelating agent, sebum regulating agent, and solvent. In some embodiments, the composition is a hair or scalp composition. In some embodiments, the composition described herein maintains or increases a hair property to where applied, e.g., hair and / or skin of individuals as compared to a hair property of hair not applied with the composition. In some embodiments, the composition described herein increases a hair property to where applied, e.g., hair and / or skin of individuals, when compared to no application of the composition. In some embodiments, the composition described herein increases a hair property to where applied, e.g,, hair and / or skin of individuals, when compared to a baseline measurement. In some embodiments, die composition described herein maintains a hair property to where applied, e.g., hair and / or skin of individuals, when compared to no application of the composition. In some embodiments, the composition described herein maintains a hair property to where applied, e.g., hair and / or skin of individuals, when compared to a baseline measurement. In some embodiments, tire composition described herein is applied to hair prior to heat application. Table 1 depicts non-limiting examples of compositions comprising an odor binding protein, absorbing agent, and one or more additional agents. Table 1: non-limiting examples of compositions comprising odor binding protein and absorbing agent Formulation I Ingredient Percent formula (total w.Av%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable V ariable V ariable Variable Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% 0.5 15 8 5 0.1 Formulation II Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% Variable Variable Variable Variable V ariable humectant 0.01-5% 0.05 7 0.44 1.33 0.6 Odor binding protein 0.001-1% ¢).4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% 0.5 15 8 5 0.1 Formulation III Ingredient Percent formula (total w.Av%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable Rheology modifying agent 0.005-10 ¢).3 7 0.1 0.08 1 Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% 0.5 15 8 5 0.1 Formulation IV Ingredient Percent formula (total w.Av%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Van able V ariable V ariable Variable Chelating agent 0.005-10 0.2 6 0.1 0.15 1 Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% ¢).5 15 8 5 0.1 Formulation V Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% Variable Variable Variable Variable Variable stabilizing agent 0.005-10 0.3 0.05 0.1 0.7 9 Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% 0.5 15 8 5 0.1 Formulation VI Ingredient Percent formula (total w.Av%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable preservative 0.005-10 0.01 0.06 0.95 1.5 5 Odor binding protein 0.001-1%        0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40%        0.5 15 8 5 0.1 Formulation VII Ingredient Percent formula (total vv / w%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable Variable Variable Sebum regulating agent 0.0001-1 0.0005 0.55 0.0089 0.0067 0.5 Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% 0.5 15 8 5 0.1 Formulation VIII Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable Fragrance component 0.01-10 0.05 2.5 0.25 0.4 0.5 Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15 0.05 Absorbing agent 0.01-40% 0.5 15 8 5 0.1 Formulation IX Ingredient Percent formula (total w / w%) Example A Example B Example C Example Example D      E Solvent 35-99% Variable Variable Variable Variable Variable Buffering agent 0.001-1 0.069 0.71 0.057 0.4         0.9 Odor binding protein 0.001-1% 0.4 0.03 0.01 0.15        0.05 Absorbing agent 0.01-40% 0.5 15 8 5            0.1

[0196] In certain embodiments, a composition (e.g., a composition provided herein) comprises an odor binding protein and a sebum regulating agent. In specific embodiments, the composition comprises an odor binding protein, a sebum regulating agent, and one or more of: a solvent, humectant, rheology modifying agent, chelating agent, absorbing agent, fragrance component, buffering agent. In yet more specific embodiments, the composition comprises an odor binding protein, sebum regulating agent, humectant, rheology modifying agent, chelating agent, absorbing regulating agent, fragrance component, buffering agent, and solvent. In still more specific embodiments, the composition comprises an odor binding protein, sebum regulating agent, buffering agent, and solvent. In yet more specific embodiments, the composition comprises an odor binding protein, sebum regulating agent, humectant, rheology modifying agent, buffering agent, and solvent. In still more specific embodiments, the composition comprises an odor binding protein, sebum regulating agent, absorbing agent, rheology modifying agent, chelating agent, and solvent. In some embodiments, the composition is a hair or scalp composition. In some embodiments, the composition described herein maintains or increases a hair property to where applied, e.g., hair and / or skin of individuals as compared to a hair property of hair not applied with the composition. In some embodiments, the composition described herein increases a hair property where applied, e.g., hair and / or skin of individuals, when compared to no application of the composition. In some embodiments, the composition described herein increases a hair property where applied, e.g., hair and / or skin of individuals, when compared to a baseline measurement. In some embodiments, the composition described herein maintains a hair property to where applied, e.g., hair and / or skin of individuals, when compared to no application of the composition. In some embodiments, the composition described herein maintains a hair property' to where applied, e.g., hair and / or skin of individuals, when compared to a baseline measurement. In some embodiments, the composition described herein is applied to hair prior to heat application. Table 2 depicts non-limiting examples of compositions comprising an odor binding protein, sebum regulating agent, and one or more additional agents. Table 2: non-limiting examples of compositions comprising odor binding protein and sebum regulating agent Formulation I Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.25 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation II Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable humectant 0.01-5% 0.44 2.5 0.05 0.03 4 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.2.5 Sebum regulating agent 0.0()01-1% ¢).0089 0.3 0.0065 0.03 0.5 Formulation III Ingredient Percent formula (total w / w%) Example A Example B Example C ' Example D Example E Solvent 35-99% Variable Variable Variable Variable V ariable Rheology modifying agent 0.005-10% 0.1 5 0.88 2 0.05 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.2.5 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation IV Ingredient Percent formula (total w / w%) Example A Example B Example C ' Example D Example E Solvent 35-99% Variable Variable Variable Variable V ariable Chelating agent 0.005-10 0.1 0.2 0.4 2 5 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.25 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation V Ingredient Percent formula (total w.Av%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable stabilizing agent 0.005-10 0.1 0.14 0.025 0.5 9.2 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.25 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation VI Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% V ariable Variable Variable V ariable Variable preservative 0.005-10 0.95 1 0.85 1.5 0.05 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.2.5 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation VII Ingredient Percent formula (total w / w%) Example A Example B Example C ' Example D Example E Solvent 35-99% Variable Variable Variable Variable V ariable Absorbing agent 0.01-40% 8 15 10 0.5 35 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.25 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation VIII Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% Variable Variable Variable Variable Variable Fragrance component 0.01-10% 0.25 0.35 7 3.1 0.5 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.25 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5 Formulation IX Ingredient Percent formula (total w / w%) Example A Example B Example C Example D Example E Solvent 35-99% Variable Variable Variable Variable Variable Buffering agent 0.001-1 ¢).057 0.6 0.035 0.2 0.9 Odor binding protein 0.001-1% 0.01 0.02 0.9 0.13 0.25 Sebum regulating agent 0.0001-1% 0.0089 0.3 0.0065 0.03 0.5

[0197] In another aspect, the present disclosure provides a method for reducing malodor of a hair and / or scalp of an individual, where the method comprising administering an effective amount of the composition described herein to the hair and / or scalp of die individual.

[0198] In one aspect, the present disclosure provides a method for reducing sebum in a hair and / or scalp of an individual, the method comprising administering an effective amount of the composition described herein to the hair and / or scalp of the individual.

[0199] In another aspect, the present disclosure provides a method for reducing sebum on a hair and / or scalp of an individual, where the method comprising administering an effective amount of a composition comprising an odor binding protein to the hair and scalp of the individual. In some instances, the odor binding protein comprises a sequence at least about 80%, at least about 85%, at least about 90%, at least about 95%, at least about 96%, at least about 97%, at least about 98%, or at least about 99% identical to any one of SEQ ID NOS: 1-340. In some instances, the odor binding protein comprises a sequence at least about 80% identical to any one of SEQ ID NOS: 1-340. In some instances, the composition further comprises an absorbing agent. In some instances, the composition further comprises a sebum reducing agent.

[0200] In some instances, skin surface levels of sebum of area where applied, e.g., the hair and scalp, are reduced compared to a baseline measurement for about 2.4 to about 72 hours or more after administration of the composition. In some instances, sebum reduction is measured by a Sebumeter.

[0201] In some instances, when measured immediately after administration compared to a baseline measurement, sebum is reduced about 1 to about 20 pg / cm2. In some instances, when measured immediately after administration compared to a baseline measurement, sebum is reduced about 5 to about 15 pg / cm2. In some instances, when measured immediately after administration compared to a baseline measurement, sebum is reduced by about 10 pg / cm2.

[0202] In some instances, when measured immediately after administration compared to a baseline measurement, the sebum is reduced by about 10%, about 20%, about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, about 90%, or about 100%. In some instances, when measure immediately after administration compared to a baseline measurement, the sebum is reduced by at least 10%, at least 20%, at least 30%, at least 40%, at least 50%, at least 60%, at least 70%, at least 80%, at least 90%, or at least 100%. In some instances, when measure immediately after administration compared to a baseline measurement, the sebum is reduced by at most 10%, at most 20%, at most 30%, at most 40%, at most 50%, at most 60%, at most 70%, at most 80%, at most 90%, or at most 100%. In some instances, when measure immediately after administration compared to a baseline measurement, tire sebum is reduced by between 10% to 100%, between 20% to 100%, between 30% to 100%, between 40% to 100%, between 50% to 100%, between 60% to 100%, between 70% to 100%, between 80% to 100%, or between 90% to 100%.

[0203] In some instances, when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 19 ug / cm2. In some instances, when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced about 4 to about 14 pg / cm2. In some instances, when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced by about 9 pg / cm2.

[0204] In some instances, when measured about 12 hours after administration compared to a baseline measurement, the sebum is reduced by about 10%, about 20%, about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, about 90%, or about 100%. In some instances, when measured about 12. hours after administration compared to a baseline measurement, the sebum is reduced by at least 10%, at least 20%, at least 30%, at least 40%, at least 50%, at least 60%, at least 70%, at least 80%, at least 90%, or at least 100%. In some instances, when measured about 12 hours after administration compared to a baseline measurement, th...

Claims

1. A composition comprising:an odor binding protein comprising a sequence at least about 80% identical to any one of SEQ ID NOS: 1-340; andan absorbing agent.

2. The composition of claim 1, wherein the absorbing agent binds to and / or absorbs oil and sebum.

3. The composition of claim I or claim 2, wherein the absorbing agent comprises a compound comprising silicon.

4. The composition of claim 3, wherein the compound comprises silica, a silicate salt, silica silylate, silica dimethyl silylate, silica dimethicone silylate, or a combination of two or more thereof.

5. The composition of any one of the preceding claims, wherein the absorbing agent comprises silica.

6. The composition of any one of the preceding claims, wherein the absorbing agent comprises a carbonate salt, metal oxide, clay mineral powder, or a combination of two or more thereof7. The composition of any one of the preceding claims, wherein the absorbing agent is from about 0.01% to about 40% by weight (w / w) of the composition.

8. The composition of any one of the preceding claims, wherein die absorbing agent is from about 1% to about 25% by weight (w / w) of the composition.

9. The composition of any one of tire preceding claims, wherein the absorbing agent is from about 2% to about 15% by weight (¾7.¼) of the composition.

10. The composition of any one of the preceding claims, wherein the absorbing agent comprises silica from about 2% to about 15% by weight (w / w) of the composition.

11. The composition of any one of the preceding claims, further comprising a sebum regulating agent.

12. The composition of any one of the preceding claims, wherein, when applied to hair, the composition maintains or increases a hair property' as compared to the hair property' of hair not applied with the composition, wdierein the hair property comprises hair strength, hair color, hair elasticity', hair luster, hair porosity', or a combination thereof.

13. The composition of claim 12, wherein the hair elasticity is determined by measuring a Young’s Modulus of hair.

14. The composition of claim 12, wherein the hair color is determined by a color fade assay.

15. The composition of claim 12, wherein the hair strength is determined by a break stress.

16. The composition of claim 12, wherein the hair luster is determined by polarized spectroscopy, imaging, or both.

17. The composition of claim 12, wherein the hair porosity' is determined by measuring a density' of hair.

18. The composition of any one of the preceding claims, wherein the composition is applied to the hair prior to heat application.

19. A composition comprising:an odor binding protein comprising a sequence at least about 80% identical to any one of SEQ ID NOS: 1-340; anda sebum regulating agent.

20. The composition of any one of claims 11-19, wherein the sebum regulating agent comprises bioactive compounds for reducing sebum and oil.

21. The composition of claim 19 or claim 20, wherein the sebum regulating agent reduces, regulates, or removes sebum and / or sweat.

22. The composition of any one of claims 11-21, wherein the sebum regulating agent comprises salicylic acid, microalgae extracts, green tea emulsions, avocado extract, Opuntia ficus-indica stem extract, Anetholes anisate leaf extract, Tetraselmis Suecica extract, Alteromonas ferment extract, Pseudoalteromonas ferment extract, Corylus avellana leaf extract, Phyllanthus emblica fruit extract, Saccharum officinanim (sugarcane) extract, Rhodomyrtus tomentosa fruit extract, Hedychium coronarium root extract, Epilobium angustifolium flower / leaf / stem extract, Tremella fuciformis sporocarp extract, or a combination of two or more thereof.

23. The composition of any one of claims 11-22, wherein the sebum regulating agent comprises tetraselmis suecica extract.

24. The composition of any one of claims 11-23, wherein the sebum regulating agent is from about 0.0001% to about 1% by weight (w / w) of the composition.

25. The composition of any one of claims 11-24, wherein the sebum regulating agent is from about 0.0005% to about. 0.5% by weight. (wAv) of the composition.

26. The composition of any one of claims 11-25, wherein tire sebum regulating agent is from about 0.001% to about 0.05% by weight ( wAv) of the composition.

27. The composition of any one of claims 11-26, wherein the sebum regulating agent comprises tetraselmis suecica extract from about 0.001% to about 0.05% by weight (w / w) of the composition.

28. The composition of any one of the preceding claims, -wherein the composition has a pH from about 6 to about 9.

29. The composition of any one of the preceding claims, wherein the composition has a pH from about 7 to about 7.5.

30. The composition of any one of the preceding claims, further comprising a buffering agent.

31. The composition of claim 30, wherein the buffering agent maintains the pH of tire composition.

32. The composition of claim 30 or claim 31, wherein the buffering agent comprises a weak acid, ■weak base, ammo acid, weak organic acid, weak organic base, or combinations of two or more thereof.

33. The composition of any one of ciaims 30-32, wherein the buffering agent comprises citric acid, lactic acid, glycolic acid, malic acid, tartaric acid, arginine, tromethamine, sodium hydroxide, potassium hydroxide, or a combination of two or more thereof.

34. The composition of any one of claims 30-33, wherein the buffering agent comprises lactic acid, citric acid, tromethamine, and arginine.

35. The composition of any one of claims 30-34, wherein buffering agent is from about 0.001% to about 1% by weight (w / w) of the composition.

36. The composition of any one of claims 30-35, wherein the buffering agent is from about 0.005% to about 0.5 by weight (w7w) of the composition.

37. The composition of any one of claims 30-36, wherein the buffering agent is from about 0.01% to about 0.1% by weight (w / w) of the composition.

38. The composition of any one of claims 30-37, wherein the buffering agent comprises lactic acid from about 0.0005% to about 0.01% by weight (w / w), citric acid from about 0.01% to about 0.1% (w / w), tromethamine from about 0.001% to about 0.05% (w / w), and arginine from about 0.000075% to about 0.005% (w / w) of the composition.

39. The composition of any one of the preceding claims, wherein the sequence is at least about 90% identical to any one of SEQ ID NOS: 1-340.

40. The composition of any one of the preceding claims, wherein die odor binding protein binds to an odorant molecule.

41. The composition of any one of the preceding claims, wherein the odor binding protein is from about 0.001% to about 1% by weight (w / w) of the composition.

42. The composition of any one of the preceding claims, wherein the odor binding protein is from about 0.0025% to about 0.5% by weight (w / w) of the composition.

43. The composition of any one of the preceding claims, wherein the odor binding protein is from about 0.0()5% to about 0.1% by weight (w / w) of the composition.

44. The composition of any one of the preceding claims, further comprising a solvent.

45. The composition of claim 44, wherein the solvent comprises a polar solvent, nonpolar solvent, water, alcohol, polyol, glycol, sugar, polyethylene glycol, or a combination of two or more thereof.

46. The composition of claim 44 or claim 45, wherein the solvent comprises water, mannitol, dimethyl isosorbide, triethyl citrate, phenethyl benzoate, dicaprylyl maleate, dilinoleic acid / propanediol copolymer, denatured ethanol, denatured methanol, denatured propanol, denatured isopropyl alcohol, denatured butanol, denatured pentanol, denatured hexanol, methanol, ethanol, propanol, isopropyl alcohol, butanol, pentanol, hexanol, glycerin, butylene glycol, isoprene glycol, propylene glycol, dipropylene glycol, propanediol, isopentyldiol, polyethylene glycols, sorbitol, glucose, fructose, maltose, lactose, sucrose, PEG-4, PEG-6, PEG-8, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18, PEG-20, or a combination of two or more thereof.

47. The composition of any one of claims 44-46, wherein the solvent comprises water, mannitol, glycerin, and denatured ethanol.

48. The composition of any one of claims 44-47, wherein the solvent comprises water and denatured ethanol.

49. The composition of any one of claims 44-48, wherein the solvent is from about 35% to about 99% by weight (w / w) of tire composition.

50. The composition of any one of claims 44-49, wherein the solvent is from about 60% to about 97% by weight (w7w) of the composition.

51. The composition of any one of claims 44-50, wherein solvent is from about 80% to about 95% by weight (w / w) of the composition.

52. The composition of any one of claims 44-51, wherein the solvent comprises water from about 45% to about 85% by weight (w / w), mannitol from about 0.02% to about 0.1% (w / w), glycerin from about 0.1% to about 1% (w / w), and denatured ethanol from about 10% to about 30% (w / w) of the composition.

53. The composition of any one of claims 44-52, wherein the solvent comprises water from about 45% to about 85% by weight (w7w) and denatured ethanol from about 10% to about 30% (w7w) of die composition.

54. The composition of any one of the preceding claims, further comprising a humectant.

55. The composition of claim 54, wherein the humectant comprises a hyaluronate, glycol, sorbitol, sugar, carbocyclic sugar, alcohol, or a combination of two or more thereof.

56. The composition of claim 54 or claim 55, wherein the humectant comprises 1,2,6 hexanetriol, dipropylene glycol, glycerin, butylene glycol, caprylyl glycol, pentylene glycol, isopentyldiol, hexylene glycol, panthenol, phytantriol, propylene glycol, propanediol, sodium PCA, sorbitol, triethylene glycol, polyglyceryl sorbitol, glucose, fructose, mannitol, xylitol, inositol, trehalose, polydextrose, potassium PCA, hydrogenated honey, hyaluronic acid, hydrolyzed hyaluronic acid, sodium hyaluronate, inositol, erythritol, capry l glycol, acetamidoethoxyethanol, or a combination of two or more thereof.

57. The composition of any one of claims 54-56, wherein the humectant comprises glycerin, mannitol, sodium hyaluronate, and hydrolyzed hyaluronic acid.

58. The composition of any one of claims 54-57, wherein the humectant is from about 0.01% to about 5% by weight (w / w) of the composition.

59. The composition of any one of claims 54-58, the humectant is from about from about 0.1% to about. 2% by weight (w / w) of the composition.

60. The composition of any one of claims 54-59, wherein the humectant is from about 0.25% to about 1% by weight (wAv) of the composition.

61. The composition of any one of claims 54-60, wherein the humectant comprises mannitol from about ¢).02% to about 0.1% by weight (w / w), glycerin from about 0.1% to about 1% (w / w), sodium hyaluronate from about 0.001% to about 0.01% (w / w), and hydrolyzed hyaluronic acid from about 0.001% to about 0.1% (w / w) of the composition.

62. The composition of any one of the preceding claims, further comprising a rheology modifying agent.

63. The composition of claim 62, wherein the rheology modifying agent comprises a hydrocolloid, naturally derived polymer, aqueous natural polymer, sugars, or a combinations of two or more thereof.

64. The composition of claim 62 or claim 63, wherein the rheology modifying agent comprises pectin, gellan gum, carrageen, glycerin, agar, xanthan gum, pullulan, algin, tetragonoloba (guar) gum, sclerotium gum, acacia Senegal gum, cellulose, cellulose gum, carboxymethylcellulose, carbomer, hydroxypropyl starch phosphate, guar hydroxy propyltrmionium chloride, carboxymethyl hydroxyethyl cellulose, carboxymethyl hydroxypropyl guar, cellulose, ethyl cellulose, hydroxybutyl methylcellulose, hydroxyethylcellulose, hydroxymethylcellulose, lauryl poly glucose, or a combination of two or more thereof.

65. The composition of any one of claims 62-64, wherein the rheology modifying agent comprises gellan gum.

66. The composition of any one of claims 62-65, wherein the rheology modifying agent is from about 0.005% to about 10% by weight (w / w) of tire composition.

67. The composition of any one of claims 62-66, wherein the rheology modifying agent is from about 0.01% to about 2% by weight (w / w) of the composition.

68. The composition of any one of claims 62-67, wherein die rheology modifying agent is from about 0.05% to about 0.5% by weight (wAv) of the composition.

69. The composition of any one of claims 62-68, wherein the rheology modifying agent comprises gellan gum from about 0.05% to about 0.5% by (w-. / w) of the composition.

70. The composition of any one of the preceding claims, further comprising a stabilizing agent.

71. The composition of claim 70, wherein the stabilizing agent comprises a salt, sulfate, or a combination of two or more thereof.

72. The composition of claim 70 or claim 71, wherein the stabilizing agent comprises calcium chloride, magnesium chloride, magnesium sulfate, potassium chloride, potassium glycol sulfate, sodium chloride, or a combination of two or more thereof73. The composition of any one of claims 70-72, wherein the stabilizing agent comprises sodium chloride.

74. The composition of any one of claims 70-73, wherein the stabilizing agent is from about 0.005% to about 10% by weight (w / w) of the composition.

75. The composition of any one of claims 70-74, wherein the stabilizing agent is from about 0.01% to about 2% by weight (wAv) of the composition.

76. The composition of any one of claims 70-75, wherein the stabilizing agent is from about 0.05% to about 0.5% by weight (w.Av) of the composition.

77. The composition of any one of claims 70-76, wherein the stabilizing agent comprises sodium chloride from about 0.05% to about 0.5% by weight (w / w) of tire composition.

78. The composition of any one of the preceding claims, further comprising a chelating agent.

79. The composition of claim 78, wherein the chelating agent comprises EDTA, sodium phytate, sodium gluconate, trisodium dicarboxymethyl alanmate, tetrasodium glutamate diacetate, capryl hydroxamic acid, or a combination of two or more thereof.

80. The composition of claim 78 or claim 79, wherein the chelating agent comprises sodium phytate.

81. The composition of any one of claims 78-80, wherein the chelating agent is from about 0.005% to about 10% by weight (wAv) of the composition.

82. The composition of any one of claims 78-81, wherein the chelating agent is from about 0.01% to about. 2% by weight (w / w) of the composition.

83. The composition of any one of claims 78-82, wherein the chelating agent is from about 0.05% to about 0.5% by weight (w / w) of the composition .

84. The composition of any one of the claims 78-83, wherein the chelating comprises sodium phytate from about 0.05% to about 0.5% by weight (w / w) of the composition.

85. The composition of any one of the preceding claims, further comprising a preservative.

86. The composition of claim 85, wherein the preservative comprises an alcohol, paraben, formaldehyde release, carbamate, sorbate, or a combination of two or more thereof.

87. The composition of claim 85 or claim 86, wherein the preservative comprises benzyl alcohol, benzoic acid, butyl paraben, diazolidinyl urea, DMDM hydantoin, ethyl paraben, imidazolidinyl urea, iodopropynyl butylcarbamate, isobutyl paraben, methyl paraben, methylchloroisothiazolinone, methylisothiazolinone, phenoxyethanol, propyl paraben, sodium benzoate, potassium sorbate, ethylhexylglycerin, gluconolactone, or a combination of two or more thereof.

88. The composition of any one of claims 85-87, wherein the preservative comprises benzyl alcohol.

89. The composition of any one of claims 85-88, wherein the preservative is from about 0.005% to about 10% by w eight (w / w) of tire composition.

90. The composition of any one of claims 85-89, wherein the preservative is from about 0.01% to about. 5% by weight (w / w) of the composition.

91. The composition of any one of claims 85-90, wherein the preservative is from about 0.5% to about 2% by weight (w.Av) of the composition.

92. The composition of any one of claims 85-91, wherein the preservative comprises benzyl alcohol from about 0.5% to about 2% by weight (w / w) of the composition.

93. The composition of any one of the preceding claims, wherein the composition is a suspension.

94. The composition of claim 93, wherein the suspension comprises a non-aerosol hydroalcoholic formulation.

95. The composition of any one of tire preceding claims, wherein tire composition is a hair or scalp composition.

96. The composition of any one of the preceding claims, wherein, when applied to the hair, the composition maintains or increases the hair property as compared to the hair property of hair not applied with the composition.

97. The composition of any one of tire preceding claims, wherein the composition is applied to the hair prior to heat application.

98. A method for reducing malodor of a hair and / or scalp of an individual, the method comprising administering an effective amount of the composition of any one of the preceding claims to the hair and / or scalp of the individual.

99. A method for reducing sebum in a hair and / or scalp of an individual, the method comprising administering an effective amount of the composition of any one of claims 1-86 to the hair and / or scalp of the individual.

100. A method for reducing sebum on a hair and / or scalp of an individual, the method comprising administering an effective amount of a composition comprising an odor binding protein to the hair and scalp of the individual, wherein the odor binding protein comprises a sequence at least about 80% identical to any one of SEQ ID NOS: 1-340.

101. The method of claim 100, wherein the composition further comprises an absorbing agent.

102. The method of claim 100 or claim 101, wherein the composition further comprises a sebum reducing agent.103, The method of any one of claims 100-102, wherein skin surface levels of sebum are reduced compared to a baseline measurement for about 24 to about 72 hours or more after administration of the composition.

104. The method of any one of claims 100-103, wherein sebum reduction is measured by a Sebumeter.

105. The method of any one of claims 100-104, wherein when measured immediately after administration compared to a baseline measurement, sebum is reduced about 1 to about 20 pg / cm2.106, The method of any one of claims 100-105, wherein when measured immediately after administration compared to a baseline measurement, sebum is reduced about 5 to about 15 pg / cm2.

107. The method of any one of claims 100-106, wherein when measured immediately after administration compared to a baseline measurement, sebum is reduced by about 10 pg / cnr.108, The method of any one of claims 100-107, wherein when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 19 pg / cm2.

109. The method of any one of claims 100-108, wherein when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced about 4 to about 14 ug / cm2.

110. The method of any one of claims 100-109, wherein when measured about 12 hours after administration compared to a baseline measurement, sebum is reduced by about 9 pg / cm2.

111. The method of any one of claims 100-110, wherein when measured about 24 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 17 pg / cm2.

112. The method of any one of claims 100-111, wherein when measured about 24 hours after administration compared to a baseline measurement, sebum is reduced about 3 to about 12 pg / cm2.

113. The method of any one of claims 100-112, wherein when measured about 24 hours after administration compared to a baseline measurement, sebum is reduced by about 7 pg / cm2.

114. The method of any one of claims 100-113, wherein when measured about 48 hours after administra tion compared to a baseline measurement, sebum is reduced about 1 to about 15 pg / cm2.

115. The method of any one of claims 100-114, wherein when measured about 48 hours after administration compared to a baseline measurement, sebum is reduced about 2 to about 10 pg / cm2.

116. The method of any one of claims 100-115, wherein when measured about 48 hours after administration compared to a baseline measurement, sebum is reduced by about 5.5 ug / cm2.

117. The method of any one of claims 100-116, wherein when measured about 72 hours after administration compared to a baseline measurement, sebum is reduced about 1 to about 8 pg / cm2.

118. The method of any one of claims 100-117, wherein when measured about 72 hours after administration compared to a baseline measurement, sebum is reduced about 2 to about 6 ug / cm2.

119. The method of any one of claims 100-118, wherein when measured about 72 hours after administration compared to a baseline measurement, sebum is reduced by about 4 pg / cm2.

120. A method for reducing malodor on a hair and / or scalp of an individual, the method comprising administering an effective amount of a composition comprising an odor binding protein to the hair and scalp of the individual, wherein the odor binding protein comprises a sequence at least about 80% identical to any one of SEQ ID NOS: 1-340.

121. The method of claim 120, wherein tire composition further comprises an absorbing agent.

122. The method of claim 120 or claim 121, wherein the composition further comprises a sebum reducing agent.

123. The method of any one of claims 120-122, wherein malodor levels are reduced compared to a baseline measurement for about 2.4 to about 72. hours or more after administration of the composition.

124. The method of any one of claims 120-123, wherein malodor levels are evaluated by a trained odor grader on a scale of 0 to 10.

125. The method of claim 124, wherein when measured immediately after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 7 on the scale.

126. The method of claim 124 or claim 125, wherein when measured immediately after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 6 on the scale.

127. The method of any one of claims 124-126, wherein when measured immediately after administration compared to a baseline measurement, malodor levels are reduced by about 5 on the scale.

128. The method of any one of claims 124-127, wherein when measured about 12 hours after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 7 on the scale.

129. The method of any one of claims 124-128, wherein when measured about 12 hours after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 6 on the scale.

130. The method of any one of claims 124-129, wherein when measured about 12 hours after administration compared to a baseline measurement, malodor levels are reduced by about 5 on the scale.

131. The method of any one of claims 124-130, wherein when measured about 24 hours after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 6 on the scale.

132. The method of any one of claims 124-131, wherein when measured about 24 hours after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 5 on the scale.

133. The method of any one of claims 124-132, wherein when measured about 24 hours after administration compared to a baseline measurement, malodor levels are reduced by about 4 on the scale.

134. The method of any one of claims 124-133, wherein when measured about 48 hours after administration compared to a baseline measurement, malodor levels are reduced about 2 to about 5 on the scale.

135. The method of any one of claims 124-134, wherein when measured about 48 hours after administration compared to a baseline measurement, malodor levels are reduced about 3 to about 4 on the scale.

136. The method of any one of claims 124-135, wherein when measured about 48 hours after administration compared to a baseline measurement, malodor levels are reduced by about 3.5 on the scale.

137. The method of any one of claims 124-136, wherein when measured about 72 hows after administration compared to a baseline measurement, maiodor levels are reduced about 1 to about 4 on the scale.

138. The method of any one of claims 124-137, wherein when measured about 72 hours after administration compared to a baseline measurement, maiodor levels are reduced about 2 to about 3 on the scale.

139. The method of any one of claims 124-138, wherein when measured about 72 hows after administration compared to a baseline measurement, maiodor levels are reduced by about 2.5 on the scale.

140. The method of any one of the preceding claims, wherein, when applied to the hair, the composition maintains or increases a hair property as compared to the hair property of hair not applied with the composition.

141. The method of any one of the preceding claims, wherein the composition is applied to the hair prior to heat application.