A reagent kit and a reagent disk device

Abstract

The present invention discloses a reagent kit and a reagent disk device, the reagent kit comprising: a reagent kit body, which is detachably connected to a reagent disk matched with the reagent kit body, comprising a first reagent bottle area and a second reagent containing area, the first reagent bottle area is provided with a first reagent bottle assembly circular hole on a first pitch circle, and the second reagent containing area is provided with a plurality of second reagent containing cavities on a second pitch circle. By the above method, the suction action process of the sample to be tested can be simplified.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a reagent kit and a reagent disk device. Background Art

[0002] Medical reagent analyzers are instruments that detect and analyze samples and can provide important data support for the diagnosis, treatment and prevention of diseases.

[0003] Existing medical reagent analyzers usually include a reagent kit part and a reagent kit tray that cooperates with the reagent kit, and the reagent kit usually includes multiple reagent samples to be tested. Accordingly, the sample aspirator needs to move multiple times in the radial direction to absorb samples from different reagent bottles respectively, and the action process is relatively complicated.

[0004] The inventor of the present application provides a novel reagent kit and reagent disk device, which can simplify the action process of the sample aspiration needle. Summary of the invention

[0005] The main technical problem solved by the present invention is to provide a reagent kit and a reagent disk device, which can simplify the aspiration process of a sample to be tested by a medical analyzer.

[0006] In order to solve the above technical problems, a technical solution adopted by the present invention is: providing a kit.

[0007] The kit includes:

[0008] The reagent box body is detachably connected to a reagent tray assembly matching the reagent box body, and includes a first reagent bottle area and a second reagent containing area. The first reagent bottle area is provided with a first reagent bottle assembly circular hole on a first pitch circle, and the second reagent containing area is provided with a plurality of second reagent containing cavities on a second pitch circle.

[0009] In order to solve the above technical problem, another technical solution adopted by the present invention is: to provide a reagent disk device.

[0010] Wherein, the reagent disc device comprises:

[0011] A plurality of the reagent kits and a reagent tray for assembling the plurality of the reagent kits, wherein the reagent tray is detachably connected to the reagent kits.

[0012] The beneficial effect of the present invention is that, different from the prior art, the present invention arranges the first reagent bottle area on the first pitch circle, and arranges the second reagent containing area including a plurality of second reagent containing cavities on the second pitch circle, and during the sampling process, the sampling needle only needs to move radially from the first pitch circle to the second pitch circle. When sampling the samples to be tested in the plurality of second reagent containing cavities located on the same pitch circle, it is only necessary to move the reagent kit body circumferentially, so that the motion sequence of the sampling process can be effectively reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:

[0014] Figure 1 It is a schematic structural diagram of an embodiment of a kit of the present invention;

[0015] Figure 2 The present invention Figure 1 A top view of the reagent kit;

[0016] Figure 3 It is a structural schematic diagram of an embodiment of a first reagent bottle in the present invention;

[0017] Figure 4 yes Figure 3 A cross-sectional view of the first reagent bottle;

[0018] Figure 5 It is a structural schematic diagram of an embodiment of a reagent disc device of the present invention;

[0019] Figure 6 It is a schematic structural diagram of an embodiment of a reagent disc assembly of the present invention;

[0020] Figure 7 yes Figure 6 A schematic structural diagram of an embodiment of a reagent disc. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] See also Figure 1 and Figure 2 , Figure 1 is a schematic structural diagram of an embodiment of a kit, Figure 2 The present invention Figure 1 A top view of a kit in FIG. 1 , wherein the kit includes:

[0023] The reagent kit body is detachably connected to a reagent tray matched with the reagent kit body, and includes a first reagent bottle area 100 and a second reagent bottle area 200. The first reagent bottle area 100 is provided with a first reagent bottle assembly circular hole 110 on a first pitch circle, and the second reagent bottle area 200 is provided with a plurality of second reagent containing cavities 210 on a second pitch circle.

[0024] In this embodiment, by arranging the first reagent bottle area 100 on the first pitch circle, and arranging the second reagent containing area 200 including the plurality of second reagent containing cavities 210 on the second pitch circle, during the sampling process, the sampling needle only needs to move radially from the first pitch circle to the second pitch circle. When sampling the samples to be tested in the plurality of second reagent containing cavities located on the same pitch circle, it is only necessary to move the reagent kit body circumferentially, so that the motion sequence of the sampling process can be effectively reduced.

[0025] In one embodiment, the reagent kit further comprises: a first reagent bottle 120, which is accommodated in the first reagent bottle assembly circular hole 110; and the second reagent containing cavity 210 is used to contain reagents. A first sampling port and a second sampling port are respectively provided at the first pitch circle and the second pitch circle positions, and by rotating the reagent disk matched with the reagent kit body, a plurality of the second reagent bottles are aligned with the second sampling ports at the second pitch circle positions for sampling.

[0026] Furthermore, since the shape of the reagent box body is rectangular or sector-shaped, in one embodiment, the shape of the reagent box body is sector-shaped, at this time, the first reagent bottle area 100 is located near the center of the sector, and the second reagent bottle area 200 is located away from the center of the sector. In this way, the space of the reagent tray can be fully utilized, so that more reagent boxes can be accommodated on one reagent tray, further improving the detection efficiency.

[0027] In another embodiment, the number of the second reagent bottle accommodating chambers 210 is multiple, such as 3, 4, 6, 8, etc. Of course, it can also be set according to the structure of the detector and user needs, which is conducive to better meeting the detection needs. In one embodiment, the number of the second reagent accommodating chambers 210 is 4.

[0028] In one embodiment, the first reagent bottle area 100 is provided with arc concave surfaces 130 on both sides. When the reagent kit is assembled into the reagent tray, the two arc concave surfaces 130 cooperate with the convex surfaces of any two adjacent guide posts for positioning provided on the reagent tray assembly. Since the arc concave surfaces 130 cooperate with the convex surfaces of the guide posts, the reagent kit is clamped between the adjacent guide posts, which facilitates the installation of the reagent kit on the reagent tray and improves the operating efficiency.

[0029] Furthermore, the first reagent bottle area 100 is provided with annular grooves 140 at the bottom of the two arc concave surfaces 130, respectively, and the annular grooves 140 are inserted into the annular protrusions at the bottom of the guide column. The annular grooves 140 are inserted into the annular protrusions at the bottom of the guide column, which can reliably position the reagent box and prevent the reagent box from circumferential movement during the rotation process.

[0030] Furthermore, the bottoms of both sides of the second reagent containing area 200 are respectively provided with first positioning boundaries 230. When the reagent kit is assembled into the reagent tray, the two first positioning boundaries 230 cooperate with the second positioning boundaries of any two adjacent positioning blocks provided on the reagent tray assembly for positioning. The limiting blocks are provided at the periphery of the reagent tray, and the second reagent containing area 200 of the reagent kit is prevented from circumferentially moving during the rotation process by engaging the second reagent containing area 200 of the reagent kit at the first positioning boundaries 230, so that the mixing process of the reagents to be detected is more reliable and efficient.

[0031] In this embodiment, the guide column and the limiting block cooperate to respectively engage and limit the first reagent bottle area 100 and the second reagent containing area 200 of the reagent kit, so that the reagent bottle can be firmly fixed.

[0032] In another embodiment, the reagent kit further includes: a reagent kit cover 240, which is covered on the top of the plurality of second reagent containing cavities 210, so that the plurality of second reagent containing cavities 210 and the reagent kit cover 240 are integrated. Specifically, the reagent kit cover 240 is fixedly connected to the boundaries of the plurality of second reagent containing cavities 210 by ultrasonic welding.

[0033] In one embodiment, the reagent kit further includes: a plurality of second silicone sleeves 250 covering the opening of the second reagent containing chamber 210, and the second silicone sleeve 250 is fixed to the opening of the second reagent containing chamber 210 by a hot melt process. The opening is covered with aluminum foil to seal the second reagent containing chamber 210. Furthermore, the second silicone sleeve 250 is also provided with a plurality of cross notches to facilitate the insertion of the sampling needle and also to slow down the volatilization of the reagent.

[0034] Furthermore, anti-skid protrusions 260 are provided on both sides of the second reagent containing area 200. The anti-skid protrusions 260 are provided at the opening of the second reagent containing chamber 210 in the second reagent containing area 200, and can increase the friction coefficient to prevent the reagent kit from slipping when the operator grabs and places the reagent kit. There are multiple anti-skid protrusions 260, and each anti-skid protrusion 260 is cylindrical in shape.

[0035] In another embodiment, please refer to Figure 1 , Figure 3 and Figure 4 , Figure 3 is a schematic structural diagram of an embodiment of the first reagent bottle in the present invention, Figure 4 yes Figure 3 The cross-sectional view of the first reagent bottle in FIG. 1 shows that the first reagent bottle 120 includes a first reagent bottle body 211 and a first reagent bottle mouth 122 and a first reagent bottle bottom 123 respectively arranged at two ends of the first reagent bottle body 121; the outer diameter of the first reagent bottle mouth 122 is larger than the inner diameter of the first reagent bottle accommodating chamber 110, which is convenient for placing and removing the first reagent bottle 120. Further, the first reagent bottle 120 is a fluorescent reagent bottle, and at least one rib 124 is arranged in the first reagent bottle 120, and the rib 124 is arranged on the first reagent bottle body 121 and has the same extension direction as the first reagent bottle body 121, and is used to promote the generation of turbulence of the sample to be detected in the first reagent bottle 120 during the rotation of the first reagent bottle 120, so as to improve the uniformity of mixing of the sample to be detected.

[0036] Furthermore, the first reagent bottle 120 also includes a first silicone sleeve 150 covering the bottle mouth of the first reagent bottle, the first silicone sleeve 150 is fixed to the bottle mouth of the first reagent bottle by hot-melt process, and the bottle mouth is covered with aluminum foil to seal the first reagent bottle 120. Furthermore, the first silicone sleeve 150 is also provided with a cross cut to facilitate the insertion of the sampling needle and also to slow down the volatilization of the reagent.

[0037] In another embodiment, during the use of the reagent kit, the reagent tray drives the reagent tray and the reagent kit to rotate under the drive of the motor. The bottom 123 of the first reagent bottle is provided with a transmission component 125, which is used to receive power from the driven gear on the reagent tray and drive the first reagent bottle 120 to rotate. In this way, the reagent kit rotates while revolving with the reagent tray, forming a planetary gear train structure, so that the reagent kit and the sample to be tested are mixed more evenly, which is conducive to improving the accuracy of the test results.

[0038] In order to solve the above technical problem, another technical solution adopted by the present invention is: to provide a reagent disk device.

[0039] Please refer to Figure 5 and Figure 6 , Figure 5 is a schematic structural diagram of an embodiment of a reagent disc device of the present invention, Figure 6 1 is a schematic structural diagram of an embodiment of a reagent disc assembly of the present invention, wherein the reagent disc device comprises:

[0040] A plurality of reagent kits 10 and a reagent tray 20 for assembling the plurality of reagent kits 10, the reagent tray 20 being detachably connected to the reagent kits 10. Further, the reagent tray 20 comprises a plurality of reagent kit positioning devices (not shown), the reagent kit positioning devices being detachably connected to the reagent kits 10 and being used to fix the plurality of reagent kits 10. Further, Figure 5 The reagent disc assembly includes the reagent disc 20 and a reagent kit 10 mounted on the reagent disc 20.

[0041] In one embodiment, please refer to Figure 7 , Figure 7 yes Figure 6 The schematic diagram of the structure of an embodiment of the reagent tray in the figure, the reagent tray 20 also includes a fixed motor (not shown) and a fixed gear 21 arranged at the center of the reagent tray, and the reagent kit positioning device includes: a guide post 22 fixedly arranged on the periphery of the fixed gear 21; a driven gear 23 arranged between adjacent guide posts 22 and meshing with the fixed gear 21; and a limit block 24 arranged at the periphery of the reagent tray 20 and corresponding to the guide post 22. Further, the motor drives the reagent tray 20 to rotate, while the fixed gear 21 does not move. Since the driven gear 23 revolves and moves relative to the fixed gear 21, the transmission component 125 of the bottom 123 of the first reagent bottle is driven to realize the rotation of the first reagent bottle 120.

[0042] In one embodiment, please continue to refer to Figure 7 When the two sides of the first reagent bottle area 100 of the reagent kit are respectively provided with arc concave surfaces 130, the reagent disc is provided with a plurality of guide pillars 22 for positioning at corresponding intervals along the first circumferential direction, and the convex surfaces of any two adjacent guide pillars 22 match the two arc concave surfaces 130; the guide pillars 22 include a cylindrical sub-component 221 fixedly connected to the test disc and a conical sub-component 222 provided on the cylindrical sub-component 221. The end of the conical sub-component 222 away from the cylindrical sub-component 221 is a pointed end, which is convenient for inserting the reagent kit.

[0043] Furthermore, when the first reagent bottle area 100 is respectively provided with annular grooves 140 at the bottom of the two arc concave surfaces 130, the bottom of the guide column 22 is correspondingly provided with an annular protrusion 223, and the annular groove 140 can be snapped into the annular protrusion 223; the annular groove 120 is snapped into the annular protrusion 223 at the bottom of the guide column 22, so as to reliably position the reagent kit and prevent the reagent kit from circumferential movement during the rotation process.

[0044] Furthermore, when the bottoms of both sides of the second reagent containing area 200 are respectively provided with first positioning boundaries 230, the reagent disc is provided with a plurality of positioning limit blocks 24 at corresponding intervals along the second circumferential direction, each of the limit blocks 24 having a second positioning boundary (not shown), and two of the first positioning boundaries 230 are matched with the second positioning boundaries of any two adjacent limit blocks 24. The limit blocks 24 are arranged at the periphery of the reagent disc, and the second reagent containing area 200 of the reagent kit is engaged at the first positioning boundary 230 to prevent the second reagent containing area 200 of the reagent kit from circumferentially moving during the rotation process, so that the mixing process of the reagents to be detected is more reliable and efficient.

[0045] In this embodiment, the guide column 22 and the limiting block 24 cooperate to respectively engage and limit the first reagent bottle area 100 and the second reagent containing area 200 of the reagent kit, so that the reagent kit can be firmly fixed.

[0046] In addition, the reagent kit and reagent disk device disclosed in the present invention are used in a medical reagent analyzer, especially a chemiluminescence analyzer. Furthermore, the chemiluminescence analyzer is a chemiluminescence immunoassay analyzer.

[0047] In summary, the present invention discloses a reagent kit and a reagent disk device, the reagent kit comprising: a reagent kit body, which is detachably connected to a reagent disk assembly matched with the reagent kit body, including a first reagent bottle area and a second reagent containing area, the first reagent bottle area is provided with a first reagent bottle assembly circular hole on a first pitch circle, and the second reagent containing area is provided with a plurality of second reagent containing cavities on a second pitch circle. In the above manner, the present invention can simplify the suction action process of the medical analyzer for the sample to be tested.

[0048] The above description is only an implementation mode of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the present invention specification and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A kit, characterized in that: The kit comprises: A reagent box body, which is detachably connected to a reagent tray matched with the reagent box body, and includes a first reagent bottle area and a second reagent bottle area, wherein the first reagent bottle area is provided with a first reagent bottle assembly circular hole on a first pitch circle, and the second reagent bottle area is provided with a plurality of second reagent containing cavities on a second pitch circle; Wherein, arc concave surfaces are respectively arranged on both sides of the first reagent bottle area, and when the reagent kit is assembled into the reagent tray, the two arc concave surfaces cooperate with the convex surfaces of any two adjacent guide pillars for positioning provided on the reagent tray assembly; annular grooves are respectively arranged at the bottoms of the two arc concave surfaces, and an annular protrusion is correspondingly arranged at the bottom of the guide pillar, and the annular groove is engaged with the annular protrusion at the bottom of the guide pillar to position the reagent kit and limit the circumferential movement of the reagent kit during rotation; The bottoms of both sides of the second reagent bottle area are respectively provided with first positioning boundaries. When the reagent kit is assembled into the reagent disk, the reagent disk is provided with a plurality of positioning limit blocks at corresponding intervals along the second circumferential direction. The two first positioning boundaries match the second positioning boundaries of any two adjacent positioning limit blocks provided on the reagent disk assembly. The limit blocks are provided at the periphery of the reagent disk, and the second reagent bottle area of ​​the reagent kit is engaged at the first positioning boundaries to limit the circumferential movement of the second reagent bottle area of ​​the reagent kit during the rotation process. At least one rib is provided in the first reagent bottle. The rib is provided on the first reagent bottle body and has the same extension direction as the first reagent bottle body, and is used to generate turbulence for the sample to be detected in the first reagent bottle when the sample to be detected in the first reagent bottle rotates with the first reagent bottle.

2. The kit according to claim 1, characterized in that The reagent box body is fan-shaped, the first reagent bottle area is located close to the center of the fan-shaped circle, and the second reagent bottle area is located away from the center of the fan-shaped circle.

3. The kit according to claim 1, characterized in that The number of the second reagent containing chambers is 4.

4. The kit according to claim 1, characterized in that The kit also includes: The reagent box cover is arranged on the top of the plurality of second reagent containing cavities and is provided with a plurality of corresponding second reagent sampling ports.

5. The kit according to claim 4, characterized in that The reagent kit also includes: a first reagent bottle mounted in the first reagent bottle mounting circular hole, a first silicone sleeve covering the bottle mouth of the first reagent containing cavity, and a plurality of second silicone sleeves covering the openings of the second reagent containing cavities.

6. The kit according to claim 1, characterized in that Anti-slip protrusions are arranged on both sides of the second reagent bottle area.

7. A reagent disc device, characterized in that: The reagent disk device comprises a plurality of reagent kits as described in any one of claims 1 to 6 and a reagent disk for assembling a plurality of the reagent kits, wherein the reagent disk is detachably connected to the reagent kit; wherein, when arc concave surfaces are respectively provided on both sides of the first reagent bottle area of ​​the reagent kit, a plurality of guide posts for positioning are correspondingly provided at intervals along a first circumferential direction on the reagent disk, and the convex surfaces of any two adjacent guide posts cooperate with the two arc concave surfaces; annular grooves are respectively provided at the bottoms of the two arc concave surfaces, and annular protrusions are correspondingly provided at the bottoms of the guide posts, and the annular grooves are engaged in the annular protrusions at the bottoms of the guide posts, so as to position the reagent kit and limit the circumferential movement of the reagent kit during rotation; The bottoms of both sides of the second reagent bottle area are respectively provided with first positioning boundaries. When the reagent kit is assembled into the reagent disk, the reagent disk is provided with a plurality of the limiting blocks for positioning at corresponding intervals along the second circumferential direction, and the two first positioning boundaries cooperate with the second positioning boundaries of any two adjacent limiting blocks for positioning provided on the reagent disk assembly; when the bottoms of both sides of the second reagent bottle area are respectively provided with first positioning boundaries, the reagent disk is provided with a plurality of limiting blocks for positioning at corresponding intervals along the second circumferential direction, each limiting block has a second positioning boundary, and the two first positioning boundaries cooperate with the second positioning boundaries of any two adjacent limiting blocks; the limiting blocks are provided at the periphery of the reagent disk, and the second reagent bottle area of ​​the reagent kit is engaged at the first positioning boundary to limit the circumferential movement of the second reagent bottle area of ​​the reagent kit during the rotation process; At least one rib is provided in the first reagent bottle. The rib is provided on the first reagent bottle body and has the same extension direction as the first reagent bottle body, and is used to generate turbulence for the sample to be detected in the first reagent bottle when the sample to be detected in the first reagent bottle rotates with the first reagent bottle.

8. The reagent disc device according to claim 7, characterized in that: The reagent tray comprises a reagent kit positioning device for fixing a plurality of the reagent kits, and the reagent kit positioning device is detachably connected to the reagent kits.

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