Occluder without external protrusions at both ends

Abstract

The present invention discloses an occluder without external protrusion structures at both ends, which includes: a mesh body; a first closing line, the first closing line is passed through a plurality of grids composed of mesh wires at the first closing end to achieve the closing of the first closing end; a second closing line, the second closing line is passed through a plurality of grids composed of mesh wires at the second closing end to achieve the closing of the second closing end. Compared with the occluder with a threaded connector in the prior art, this solution of the present invention can reduce the difficulty of processing, reduce the defective rate, and save costs.

Description

Technical Field

[0001] The present invention relates to an occluder without external protrusion structures at both ends, which is used for treating congenital heart diseases, including atrial septal defect, patent ductus arteriosus, ventricular septal defect, patent foramen ovale, left atrial appendage, or blood vessels, other blocked tissue cavities and other diseases that need to be blocked for treatment. Background Art

[0002] In the prior art, one end of the occluder generally has a connector with an internal thread to connect to the conveyor to realize the conveyance of the occluder. Since the internal thread is difficult to process and a high defective rate is generated during the production process, this will cause waste of raw materials and increase in ineffective labor costs. With the development of degradable occluders, since it is difficult to make a degradable occluder with a threaded connector, the method of this scheme can be used to make an occluder without an external protrusion structure at both ends. When treating tumors and vascular lesions, the occluder can also be implanted in the supply blood vessel of the diseased organ to cause occlusion and interrupt blood supply, in order to achieve the purpose of controlling bleeding and treating tumors and vascular lesions. The occluder can also be placed in some tissue cavities to close the tissue cavity and cut off the transportation of internal substances.

[0003] In summary, in the prior art, the occluder connector is difficult to manufacture and increases the manufacturing cost because it has threads. Summary of the invention

[0004] The technical problem to be solved by the present invention is to overcome the defects of the prior art that the connecting piece of the occluder is difficult to manufacture and increases the manufacturing cost due to the threaded connection piece, and to provide an occluder without external protrusion structures at both ends.

[0005] The present invention solves the above technical problems through the following technical solutions:

[0006] An occluder without external protrusions at both ends is characterized in that it includes:

[0007] A mesh body, the mesh body having a first closing end and a second closing end that are arranged opposite to each other;

[0008] A first closing line, the first closing line is passed through a plurality of grids formed by the mesh wires at the first closing end to close the first closing end;

[0009] The second closing line is passed through a plurality of grids formed by the mesh wires at the second closing end to achieve the closing of the second closing end.

[0010] Preferably, the first closed end and the second closed end have no external protrusions.

[0011] In this solution, the first closing end and the second closing end have no external protrusions, which means that the outer surface of the occluder where the two closing ends of the occluder are located is a flat and smooth surface. With the above arrangement, on the one hand, the flat and smooth outer surface of the occluder without external protrusions at both ends is more conducive to the climbing of endothelial cells, which will quickly form endothelialization on the surface of the occluder, shortening the endothelialization time, that is, shortening the postoperative recovery period; on the other hand, the occluder without external protrusions at both ends causes minimal damage to surrounding tissues.

[0012] Preferably, the second closing line has an annular closing line, which is passed through a plurality of grids formed by mesh wires at the second closing end to achieve the closing of the second closing end, and the annular closing line serves as a connecting component and is connected to a conveyor for conveying the occluder with no external protruding point structure at both ends.

[0013] Preferably, the second closing line comprises a ring-shaped closing line and a conveying line, the ring-shaped closing line is passed through a plurality of grids formed by mesh wires at the second closing end to achieve the closing of the second closing end, and the two ends of the conveying line are respectively connected to the ring-shaped closing line to be connected to a conveyor for conveying the occluder having no external protruding point structure at both ends.

[0014] With the above arrangement, the conveying line can be easily connected by the connecting parts of the conveyor, so that the conveying can be achieved more reliably.

[0015] Preferably, the mesh body, the first closing line, and the second closing line are all made of implantable materials, and are selected from at least one of the following materials:

[0016] (1) Metals and their alloys, including stainless steel, cobalt-based alloys, titanium and titanium alloys, and nickel-titanium alloy shape memory materials;

[0017] (2) Non-degradable bio-inert medical polymer materials, including nylon, polyester resin, polytetrafluoroethylene, ultra-high molecular weight polyethylene, high-density polyethylene, polymethyl methacrylate, polypropylene, polycarbonate, polyurethane, silicone, and polyacrylonitrile;

[0018] (3) Degradable biomedical materials, including polylactide, polyglycolide, polycaprolactone, polydioxanone, and copolymers or mixtures of these materials.

[0019] It should be noted that the materials of the mesh body, the first closing line and the second closing line can be selected from one or more materials in any one of the categories (1) to (3), or can be selected from one or more materials in two or more categories (1) to (3).

[0020] Preferably, the mesh body is made by mesh weaving or 3D printing.

[0021] Preferably, the occluder without external protruding point structures at both ends is provided with fiber fabric, non-woven fabric or film inside.

[0022] With the above arrangement, the fiber fabric, non-woven fabric or film can provide endothelial tissue cells with a means of climbing and increase the barrier of the device to blood or body fluids.

[0023] Preferably, the occluder without external protrusion structures at both ends is: an atrial septal defect occluder, a patent ductus arteriosus occluder, a ventricular septal defect occluder, a patent foramen ovale occluder, a left atrial appendage occluder or a vascular plug.

[0024] On the basis of being in accordance with the common sense in the art, the above-mentioned preferred conditions can be arbitrarily combined to obtain the preferred embodiments of the present invention.

[0025] The positive and progressive effects of the present invention are:

[0026] The occluder with no external protruding point structure at both ends disclosed by the present invention can be closed into a ring structure with a closing line at both ends, and the closing line or the conveying line can be captured by the conveyor to realize the conveyance of the occluder; compared with the occluder with a threaded connector in the prior art, this scheme of the present invention can reduce the difficulty of processing, reduce the defective rate, and save costs. The occluder with no external protruding point structure at both ends has good fit, can safely and effectively block heart defects or unoccluded parts, can greatly reduce the residual shunt in postoperative ultrasound examination, and can also avoid or reduce the adhesion of platelets at the exposed rivet points on the traditional rivet-type occluder with both ends, thereby reducing the risk of local thrombosis of the occluder, and fundamentally reducing the occurrence of postoperative complications of the occluder. The occluder with no external protruding point structure at both ends can also be used to treat tumors and vascular lesions. The occluder is implanted in the supply blood vessel of the diseased organ to cause occlusion and interrupt blood supply, in order to achieve the purpose of controlling bleeding and treating tumors and vascular lesions. The occluder without external protrusion structures at both ends can also be placed in some tissue cavities to close the tissue cavities and cut off the transportation of internal substances. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a front view schematic diagram of an occluder without external protruding point structures at both ends according to Example 1 of the present invention.

[0028] Figure 2 It is a rear view schematic diagram of an occluder without external protruding point structures at both ends according to Example 1 of the present invention.

[0029] Figure 3 for Figure 1 An enlarged schematic diagram of the central part of .

[0030] Figure 4 It is a bottom view schematic diagram of an occluder without external protruding point structures at both ends according to Example 1 of the present invention.

[0031] Figure 5 It is a three-dimensional schematic diagram of an occluder without external protruding point structures at both ends according to Example 1 of the present invention.

[0032] Figure 6 It is a partial three-dimensional schematic diagram of the occluder without external protrusion structures at both ends at the second closing end of Example 2 of the present invention.

[0033] Description of reference numerals:

[0034] 1: Occluder without external protrusions at both ends

[0035] 10: Mesh

[0036] 11: First closing end

[0037] 12: Second closing end

[0038] 20: First closing line

[0039] 30: Second closing line

[0040] 31: Ring closing line

[0041] 32: Conveyor line DETAILED DESCRIPTION

[0042] A preferred embodiment is given below, and the present invention is described more clearly and completely in conjunction with the accompanying drawings.

[0043] Example 1

[0044] like Figure 1-5 As shown, the occluder 1 without external protrusion structures at both ends includes: a mesh body 10, a first closing line 20 and a second closing line 30. The structure of the mesh body 10 is similar to that of the prior art, including two mesh disks, and both mesh disks are sewn with membranes for endothelial cells to climb. In this embodiment, the two mesh disks are concave and the concave directions are the same.

[0045] The mesh body 10 has a first closing end 11 and a second closing end 12 which are arranged opposite to each other, and the first closing end 11 and the second closing end 12 have no external protrusions. Figure 1 The front one is the second closing end 12, Figure 2 The front one is the first closing end 11. The first closing line 20 is passed through a plurality of grids formed by the mesh at the first closing end 11 to achieve the closing of the first closing end 11. The second closing line 30 is passed through a plurality of grids formed by the mesh at the second closing end 12 to achieve the closing of the second closing end 12. The second closing line 30 has an annular closing line, which is passed through a plurality of grids formed by the mesh at the second closing end 12 to achieve the closing of the second closing end 12. The annular closing line is connected to the conveyor of the occluder without an external protruding point structure at both ends as a connecting component.

[0046] In this embodiment, the mesh, the first closing line, and the second closing line are all made of implantable materials, specifically nickel-titanium alloy shape memory materials. In other alternative embodiments, the mesh, the first closing line, and the second closing line can also be made of metals and their alloys, such as one or more of stainless steel, cobalt-based alloys, titanium and titanium alloys, or non-degradable bio-inert medical polymer materials, such as one or more of nylon, polyester resin, polytetrafluoroethylene, ultra-high molecular weight polyethylene, high-density polyethylene, polymethyl methacrylate, polypropylene, polycarbonate, polyurethane, silicone, polyacrylonitrile, etc., or degradable biomedical materials, such as one or more of polylactide, polyglycolide, polycaprolactone, polydioxanone, or copolymers or mixtures of these materials.

[0047] In the above, both ends are closed with closing wires to form a ring structure, wherein the closing wire at the proximal end can be captured by the conveyor to realize the delivery of the occluder. Compared with the occluder with a threaded connector in the prior art, this solution of this embodiment can reduce the risk of use and increase the speed of endothelialization.

[0048] In addition, both the first closed end and the second closed end have no external protrusions. On the one hand, the flat and smooth outer surface of the occluder without external protrusions at both ends is more conducive to the climbing of endothelial cells, which will quickly form endothelialization on the surface of the occluder and shorten the endothelialization time, that is, shorten the postoperative recovery period; on the other hand, the occluder without external protrusions at both ends causes minimal damage to surrounding tissues.

[0049] In this embodiment, the mesh body 10 is formed by weaving mesh wires. In other alternative embodiments, the mesh body 10 can also be made by 3D printing.

[0050] In addition, in this embodiment, a thin film is provided inside the occluder without external protrusion structures at both ends to allow endothelial cells to climb and to increase the device's ability to block blood or body fluids. In other alternative embodiments, a fiber fabric or non-woven fabric may also be provided inside the occluder without external protrusion structures at both ends to allow endothelial cells to climb and to increase the device's ability to block blood or body fluids.

[0051] The occluder without external protrusion structures at both ends can be: atrial septal defect occluder, patent ductus arteriosus occluder, ventricular septal defect occluder, patent foramen ovale occluder, left atrial appendage occluder or vascular plug, or other medical devices for closing tissue cavities.

[0052] Example 2

[0053] like Figure 6As shown, this embodiment 2 is similar to the embodiment 1, except that: in the embodiment 1, the second closing line 30 only includes the annular closing line, while in the embodiment 2, the second closing line 30 has an annular closing line 31 and a conveying line 32. The annular closing line 31 is passed through a plurality of grids formed by the mesh wire at the second closing end 12 to achieve the closing of the second closing end 12, and the two ends of the conveying line 32 are respectively connected to the annular closing line 31 to be connected to the conveyor of the occluder 1 having no external protruding point structure at both ends.

[0054] The conveying line 32 can be easily connected by the connecting parts of the conveyor to achieve more reliable conveying.

[0055] It should be noted that the structure of the conveying line 32 can be set to various structures according to actual needs, such as a semi-annular structure, a U-shaped structure, etc., as long as the conveying line 32 can be connected to the annular closing line 31 and can be connected to the conveyor of the occluder 1 without external protruding point structures at both ends of the conveying.

[0056] Figure 6 For illustrative purposes only, the annular closing line 31 is shown to be thicker than it actually is.

[0057] In the description of the present invention, one embodiment may be accompanied by multiple drawings, and the drawing marks of the same components in the same embodiment are not necessarily marked in every drawing; however, those skilled in the art should understand that when describing one or more drawings in an embodiment, they can be understood in conjunction with other drawings in the embodiment; those skilled in the art should understand that when it is not specified which drawing a text specifically corresponds to, it can be understood in conjunction with all drawings in the embodiment.

[0058] In the description of the present invention, it should be understood that the terms "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0059] Although the specific embodiments of the present invention are described above, it should be understood by those skilled in the art that this is only for illustration and the protection scope of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, but these changes and modifications all fall within the protection scope of the present invention.

Claims

1. An occluder without external protrusions at both ends, characterized in that: These include: A mesh body, the mesh body having a first closing end and a second closing end that are arranged opposite to each other; A first closing line, the first closing line is passed through a plurality of grids formed by the mesh wires at the first closing end to close the first closing end; A second closing line, wherein the second closing line is passed through a plurality of grids formed by the mesh wires at the second closing end to close the second closing end; The first closing end and the second closing end have no external protrusions; The second closing line has an annular closing line, which is passed through a plurality of grids formed by mesh wires at the second closing end to achieve the closing of the second closing end, and the annular closing line is used as a connecting component to be connected to a conveyor for conveying the occluder without external protrusion structures at both ends; The mesh body is made by mesh weaving or 3D printing.

2. The occluder with no external protrusion structure at both ends as claimed in claim 1, characterized in that: The mesh body, the first closing line and the second closing line are all made of implantable materials, and the implantable materials are metals and their alloy materials, including one or more of stainless steel, cobalt-based alloys, titanium and titanium alloys, and nickel-titanium alloy shape memory materials.

3. The occluder with no external protrusion structure at both ends as claimed in claim 1, characterized in that: The materials of the mesh body, the first closing line and the second closing line are all implantable materials, and the implantable materials are non-degradable bioinert medical polymer materials, including one or more of nylon, polyester resin, polytetrafluoroethylene, ultra-high molecular weight polyethylene, high-density polyethylene, polymethyl methacrylate, polypropylene, polycarbonate, polyurethane, silicone and polyacrylonitrile.

4. The occluder with no external protrusion structure at both ends as claimed in claim 1, characterized in that: The mesh body, the first closing line and the second closing line are all made of implantable materials, and the implantable materials are degradable biomedical materials, including one or more of polylactide, polyglycolide, polycaprolactone and polydioxanone, or copolymers or mixtures of these materials.

5. The occluder with no external protrusion structure at both ends as claimed in claim 1, characterized in that: The interior of the occluder without external protruding point structures at both ends is provided with fiber fabric, non-woven fabric or film.

6. The occluder without external protrusions at both ends according to any one of claims 1 to 5, characterized in that: The occluder without external protrusion structures at both ends is: an atrial septal defect occluder, a patent ductus arteriosus occluder, a ventricular septal defect occluder, a patent foramen ovale occluder, a left atrial appendage occluder or a vascular plug.

7. An occluder without external protrusion structures at both ends, characterized in that: These include: A mesh body, the mesh body having a first closing end and a second closing end that are arranged opposite to each other; A first closing line, the first closing line is passed through a plurality of grids formed by the mesh wires at the first closing end to close the first closing end; A second closing line, wherein the second closing line is passed through a plurality of grids formed by the mesh wires at the second closing end to close the second closing end; The first closing end and the second closing end have no external protrusions; The second closing line comprises an annular closing line and a conveying line, wherein the annular closing line is passed through a plurality of grids formed by mesh wires at the second closing end to achieve the closing of the second closing end, and both ends of the conveying line are respectively connected to the annular closing line to be connected to a conveyor for conveying the occluder having no external protruding point structure at both ends; The mesh body is made by mesh weaving or 3D printing.

8. The occluder with no external protrusions at both ends as claimed in claim 7, characterized in that: The mesh body, the first closing line and the second closing line are all made of implantable materials, and the implantable materials are metals and their alloy materials, including one or more of stainless steel, cobalt-based alloys, titanium and titanium alloys, and nickel-titanium alloy shape memory materials.

9. The occluder with no external protrusions at both ends as claimed in claim 7, characterized in that: The materials of the mesh body, the first closing line and the second closing line are all implantable materials, and the implantable materials are non-degradable bioinert medical polymer materials, including one or more of nylon, polyester resin, polytetrafluoroethylene, ultra-high molecular weight polyethylene, high-density polyethylene, polymethyl methacrylate, polypropylene, polycarbonate, polyurethane, silicone and polyacrylonitrile.

10. The occluder with no external protrusion structure at both ends as claimed in claim 7, characterized in that: The mesh body, the first closing line and the second closing line are all made of implantable materials, and the implantable materials are degradable biomedical materials, including one or more of polylactide, polyglycolide, polycaprolactone and polydioxanone, or copolymers or mixtures of these materials.

11. The occluder with no external protrusion structure at both ends as claimed in claim 7, characterized in that: The interior of the occluder without external protruding point structures at both ends is provided with fiber fabric, non-woven fabric or film.

12. The occluder without external protrusions at both ends according to any one of claims 7 to 11, characterized in that: The occluder without external protrusion structures at both ends is: an atrial septal defect occluder, a patent ductus arteriosus occluder, a ventricular septal defect occluder, a patent foramen ovale occluder, a left atrial appendage occluder or a vascular plug.

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