Microneedle Infusion Device
By designing a microneedle delivery device, a support platform and suction tube system are used to flatten the skin. Combined with a pressing component and a negative pressure source, the problem of traditional microneedles being difficult to insert vertically into convex and curved surfaces is solved, thereby improving drug delivery efficiency and penetration rate.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-04-24
- Publication Date
- 2026-03-03
AI Technical Summary
Traditional soluble microneedles are difficult to insert evenly and vertically into the skin on convex structures and curved areas such as the face, resulting in low drug delivery efficiency and penetration rate.
A microneedle delivery device is designed, which uses a support platform and an adsorption tube system to make the skin surface flat. The vertical insertion of soluble microneedles is achieved by pressing the component. The use of a negative pressure source and an adsorption tube ensures that the microneedles are evenly distributed and stably inserted.
It improves the conduction efficiency and drug penetration of soluble microneedles, achieving uniform drug delivery on convex and curved surfaces, and reducing pain and skin damage.
Smart Images

Figure CN111467669B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the medical and cosmetic fields, and particularly to a microneedle delivery device. Background Technology
[0002] Delivering medication correctly to the treatment site to maximize its effectiveness is a new challenge in the medical and cosmetic fields. Injection via needles is one of the most common methods of drug delivery. However, it has several drawbacks, such as pain, skin damage, bleeding, and injection site infection.
[0003] Microneedling technology effectively solves the above problems. It can painlessly create micron-sized drug delivery channels on the skin, enhancing the skin's permeability to active substances or drugs, especially macromolecular drugs. Due to its advantages such as being painless, safe, and easy to operate, especially the soluble microneedle drug delivery technology, the active drug carried in the microneedle melts and releases within the skin as it penetrates the skin.
[0004] However, traditional soluble microneedles are in the form of patches and are inserted into the skin surface by pressing with the fingers. It is difficult to effectively insert the microneedles into the skin by pressing with the fingers, especially on the face with many convex structures, wrinkles with uneven skin structure, and curved areas such as joints. It is difficult to insert the microneedles vertically into the skin, which greatly reduces the conduction efficiency and drug penetration rate of the microneedles. Summary of the Invention
[0005] This invention aims to at least solve one of the technical problems existing in the prior art. To this end, this invention proposes a microneedle delivery device that can effectively insert microneedles vertically into the skin.
[0006] According to an embodiment of the present invention, a microneedle delivery device includes: a support platform with a receiving groove at the center of its lower part; multiple first adsorption tubes installed on the support platform and distributed around the receiving groove, extending downward to the lower surface of the support platform, the first adsorption tubes being connected to a negative pressure source; and a needle-piercing part, which is received in the receiving groove and slidably connected to the support platform, with a pressing component connected to its upper end, and a patch adsorbed on its lower surface, the patch having a plurality of soluble microneedles attached thereon.
[0007] It has at least the following beneficial effects: This infusion device applies slight pressure to the lower surface of the support platform and adheres it to the skin surface. Multiple first adsorption tubes are distributed around the receiving groove and extend downward to the lower surface of the support platform, which can adsorb the skin accordingly, making the skin in curved areas smoother. The effect is more obvious on the skin with convex structures. Then, by pressing the component, several soluble microneedles are driven into the skin in the central area, achieving the effect of vertical insertion of soluble microneedles into the skin, which makes the conduction efficiency and drug penetration rate of soluble microneedles very high.
[0008] According to some embodiments of the present invention, a plurality of the first adsorption tubes are evenly distributed on the outer periphery of the support platform.
[0009] According to some embodiments of the present invention, a guide hole extending vertically through the center of the support platform is provided, the pressing assembly includes a pressing rod and a spring, the pressing rod is connected to the needle part and slidably connected to the guide hole, a stop part is installed on the pressing rod above the support platform, and the spring is disposed between the stop part and the support platform.
[0010] According to some embodiments of the present invention, the pressing rod includes a pressing portion and a sliding portion distributed from top to bottom, the size of the guide hole is larger than the size of the sliding portion and smaller than the size of the pressing portion, and the sliding portion is slidably connected to the guide hole.
[0011] According to some embodiments of the present invention, a cover is installed on the upper end of the support platform. The cover has an upper end face and an open lower end. The upper end face of the cover is provided with a through hole for the pressing rod to pass through only. The stop and the spring are stopped inside the cover.
[0012] According to some embodiments of the present invention, the spring is a compression spring and is sleeved on the outside of the pressing rod.
[0013] According to some embodiments of the present invention, the size of the needle-punched portion is larger than the size of the guide hole.
[0014] According to some embodiments of the present invention, a plurality of second adsorption tubes are installed on the needle-punched portion, the plurality of second adsorption tubes extending downward to the lower surface of the needle-punched portion, and the second adsorption tubes are connected to a negative pressure source to adsorb the patch.
[0015] According to some embodiments of the present invention, the second adsorption tube extends vertically through the support platform. Attached Figure Description
[0016] The above and / or additional aspects and advantages of the present invention will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:
[0017] Figure 1 This is a schematic diagram of the structure of an embodiment of the present invention;
[0018] Figure 2 This is a partial structural schematic diagram of an embodiment of the present invention;
[0019] Figure 3 This is a schematic diagram of another part of the structure of an embodiment of the present invention;
[0020] Figure 4 This is a schematic diagram of the present invention before the needle is inserted into the skin, according to an embodiment of the invention.
[0021] Figure 5 This is a schematic diagram of the present invention after the needle has been inserted into the skin.
[0022] Reference numerals: 1. Support platform, 11. Receiving groove, 12. Guide hole, 13. Cover, 131. First adsorption tube, 2. Needle part, 3. Pressing assembly, 4. Pressing rod, 41. Pressing part, 411. Sliding part, 412. Spring, 42. Stop part, 43. Patch, 5. Soluble microneedle, 6. Skin, 7. Second adsorption tube, 8. Detailed Implementation
[0023] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.
[0024] In the description of this invention, it should be understood that the orientation descriptions, such as up, down, front, back, left, right, etc., are based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting this invention.
[0025] In the description of this invention, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. The use of "first" and "second" in the description is merely for distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.
[0026] In the description of this invention, unless otherwise explicitly defined, terms such as "set up," "install," and "connect" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this invention in conjunction with the specific content of the technical solution.
[0027] Reference Figure 1 , Figure 4 and Figure 5 The present invention discloses a microneedle delivery device, including a support platform 1, a needle insertion part 3 and multiple first adsorption tubes 2.
[0028] The support platform 1 has a receiving groove 11 at the lower center. Multiple first adsorption tubes 2 are installed on the support platform 1 and distributed around the receiving groove 11, extending downward to the lower surface of the support platform 1. The first adsorption tubes 2 are connected to a negative pressure source. The needle part 3 is accommodated in the receiving groove 11 and is slidably connected to the support platform 1. The upper end is connected to a pressing component 4. The lower surface is adsorbed with a patch 5, and several soluble microneedles 6 are pasted on the patch 5.
[0029] Understandably, since the lower surface of the support platform 1 is flat, the soluble microneedles 6 can be moved below the lower surface of the support platform 1 to pierce the skin 7. Additionally, as... Figure 4 As shown, multiple first adsorption tubes 2 are distributed around the receiving tank 11 and extend downward to the lower surface of the support platform 1. When connected to a negative pressure source, a negative pressure is formed inside the first adsorption tubes 2, which can adsorb but not damage the skin 7. Specifically, multiple first adsorption tubes 2 can act on the skin 7 surrounding several soluble microneedles 6.
[0030] The lower surface of the support platform 1 is slightly pressed and adhered to the skin 7 surface. Multiple first adsorption tubes 2 can correspondingly adsorb the skin 7, making the skin 7 in curved areas flat, especially for convex skin 7. This prevents the soluble microneedles 6 from piercing the skin 7 at an angle. Then, the pressing component 4 drives several soluble microneedles 6 to pierce the skin 7 in the central area, achieving the effect of the soluble microneedles 6 piercing the skin 7 vertically. This makes the conduction efficiency and drug penetration rate of the soluble microneedles 6 very high.
[0031] Specifically, multiple first adsorption tubes 2 are evenly distributed on the outer periphery of the support platform 1 and fixed on the outer periphery of the support platform 1 for easy installation and disassembly.
[0032] See further Figure 2 and Figure 3 In some embodiments of the present invention, a guide hole 12 extending vertically is provided in the center of the support platform 1. The pressing component 4 includes a pressing rod 41 and a spring 42. The pressing rod 41 is connected to the needle part 3 and slidably connected to the guide hole 12. A stop part 43 is installed on the pressing rod 41 above the support platform 1. The spring 42 is disposed between the stop part 43 and the support platform 1. When the user presses the pressing rod 41 down and releases it, the pressing rod 41 can automatically spring up under the elastic force of the spring 42. Since the size of the needle part 3 is set to be larger than the size of the guide hole 12, the needle part 3 will not disengage from the receiving groove 11. The user can press the pressing rod 41 multiple times, which is conducive to the complete insertion of the soluble microneedle 6 into the skin 7.
[0033] In addition, such as Figure 2As shown, the pressing rod 41 includes a pressing part 411 and a sliding part 412 distributed from top to bottom. The size of the guide hole 12 is larger than the size of the sliding part 412 and smaller than the size of the pressing part 411. The sliding part 412 is slidably connected to the guide hole 12. The pressing part 411 will not enter the guide hole 12, thus constraining the pressing rod 41 and limiting the maximum downward distance of the pressing rod 41. This allows for a reasonable setting of the depth at which the soluble microneedles 6 penetrate the skin.
[0034] To protect the pressing lever 41 and the spring 42, such as Figure 3 As shown, a cover 13 is installed on the upper end of the support platform 1. The cover 13 has an upper end face and an open lower end. The upper end face of the cover 13 is provided with a through hole 131 for the pressing rod to pass through. The stop part 43 and the spring 42 are stopped inside the cover 13. The spring 42 is a compression spring, which is sleeved on the outside of the pressing rod 41 and can further limit the maximum distance of the pressing rod 41 moving upward.
[0035] In some embodiments of the present invention, multiple second adsorption tubes 8 are installed on the needle-punching part 3, and the second adsorption tubes 8 penetrate the support platform 1 vertically, such as... Figure 1 As shown, multiple second adsorption tubes 8 extend downwards to the lower surface of the acupuncture part 3. The second adsorption tubes 8 are connected to a negative pressure source to adsorb the patch 5. When the soluble microneedles 6 are completely inserted into the skin 7, the negative pressure source is turned off, and the second adsorption tubes 8 release the patch 5, allowing the entire infusion device to be removed. The patch 5 adheres to the surface of the skin 7. Once the soluble microneedles 6 have completely dissolved in the skin 7, the patch 5 can be removed. The operation is very convenient and facilitates the installation of the next patch 5 and soluble microneedles 6. In other embodiments, the acupuncture part 3 can also have elastic silicone protrusions arranged on its surface. The elastic silicone protrusions can form an adhesive surface that mimics the paw of a gecko, effectively adsorbing the patch 5. Of course, adsorption can also be achieved by directly using an adhesive patch or by physical adsorption.
[0036] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.
Claims
1. A microneedle delivery device, characterized in that, include: A support platform, the lower surface of which is flat, and a receiving groove is provided in the center of the lower part; Multiple first adsorption tubes are installed on the support platform and distributed around the receiving groove, extending downward to the lower surface of the support platform. The first adsorption tubes are connected to a negative pressure source, and the multiple first adsorption tubes are evenly distributed on the outer periphery of the support platform. The acupuncture part is housed in the receiving groove and slidably connected to the support platform. A pressing component is connected to the upper end, and a patch is adsorbed on the lower surface. Several soluble microneedles are attached to the patch. The lower surface of the support platform is pressed and adhered to the skin surface. Multiple first adsorption tubes act on the skin surrounding the several soluble microneedles, which can correspondingly adsorb the skin, making the skin in curved areas smooth. Multiple second adsorption tubes are installed on the acupuncture part. The multiple second adsorption tubes extend downward to the lower surface of the acupuncture part. The second adsorption tubes are connected to a negative pressure source to adsorb the patch. When the soluble microneedles are completely inserted into the skin, the negative pressure source is turned off, and the second adsorption tubes release the patch.
2. The microneedle delivery device according to claim 1, characterized in that, The support platform has a through guide hole at its center. The pressing assembly includes a pressing rod and a spring. The pressing rod is connected to the needle part and slidably connected to the guide hole. A stop part is installed on the pressing rod above the support platform. The spring is located between the stop part and the support platform.
3. The microneedle delivery device according to claim 2, characterized in that, The pressing rod includes a pressing part and a sliding part distributed from top to bottom. The size of the guide hole is larger than the size of the sliding part and smaller than the size of the pressing part. The sliding part is slidably connected to the guide hole.
4. The microneedle delivery device according to claim 2 or 3, characterized in that, The upper end of the support platform is equipped with a cover, which has an upper end face and an open lower end. The upper end face of the cover is provided with a through hole for the pressing rod to pass through. The stop and the spring are stopped inside the cover.
5. The microneedle delivery device according to claim 4, characterized in that, The spring is a compression spring and is sleeved on the outside of the pressing rod.
6. The microneedle delivery device according to claim 2 or 3, characterized in that, The size of the needle-punched part is larger than the size of the guide hole.
7. The microneedle delivery device according to claim 1, characterized in that, The second adsorption tube extends vertically through the support platform.
Citation Information
Patent Citations
Microneedle introducer
CN212395601U
Driving Microneedle Arrays into Skin and Delivering RF Energy
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