Fully automatic biological laboratory equipment cleaning, disinfection and air drying system

Abstract

The present invention provides a fully automatic biological experiment vessel cleaning, disinfection and air-drying system, comprising a cleaning and disinfection box, a support frame, a vessel support and a disinfection, cleaning and air-drying mechanism; the vessel support is arranged in the cleaning and disinfection box, and the cleaning and disinfection box is fixedly arranged on the support frame; the disinfection and cleaning mechanism comprises an upper spray assembly, a lower spray assembly and a spray assembly mounting mechanism; the upper spray assembly is fixedly arranged on the spray assembly mounting mechanism, the lower spray assembly is arranged on the spray assembly mounting mechanism and can reciprocate in the longitudinal direction, the spray assembly mounting mechanism drives the upper spray assembly and the lower spray assembly to reciprocate in the transverse direction at the same time, and the upper spray assembly and the lower spray assembly have opposite spraying directions. Through the structure of the present invention, biological experiment vessels such as blood type gradient plates can be automatically and closedly cleaned and disinfected, and human contact can be effectively avoided during the cleaning, disinfection and air-drying process to prevent cross infection and ensure biological safety in the laboratory.

Description

Technical Field

[0001] The invention relates to a cleaning, disinfecting and air-drying device, in particular to a full-automatic biological experiment vessel cleaning, disinfecting and air-drying system. Background Art

[0002] There are still many materials and utensils in the laboratories of the current health care system that need to be soaked in disinfectant and disinfected before being reused. Currently, they mainly rely on manual processing and lack suitable fully automated processing instruments and equipment, which carries a great risk of biological exposure and environmental pollution.

[0003] For example, the molecular biology techniques used in molecular diagnosis mainly include polymerase chain reaction, fluorescence quantification, DNA sequencing, fluorescence in situ hybridization, DNA imprinting technology, single nucleic acid polymorphism and gene chip. The operation of these technologies is inseparable from the detection of an important substance-viral nucleic acid. In the experiment, the test specimens contain a large number of various hidden pathogens, which have considerable biosafety risks, seriously threaten the health of the staff, and cause great interference to the experiment, especially after hundreds of millions of times of viral nucleic acid amplification test: transcription-mediated amplification test (TMA), nucleic acid polymerase chain reaction test (PCR), strict requirements on laboratory utensils are required, and they must be disinfected and cleaned in time.

[0004] Currently, the most commonly used method is to manually rinse and immerse various specimen racks used in nucleic acid experiments for disinfection. Disinfection and operation are performed in an open space, and the operator is directly exposed to specimen blood and disinfectant. In this process, the safety of the operator is greatly endangered.

[0005] Another example is the Olympus PK7300 fully automatic blood transfusion detection and analysis system, which is currently the world's top product in blood type testing and analysis technology. The application of this equipment not only saves reagents and consumables, reduces the cost of blood testing, and improves work efficiency, but its blood type trapezoidal microplate, digital imaging, data storage and output technologies provide a basis for the modern management and application of blood type testing, and reduce the risks caused by human errors. In particular, the unique blood type trapezoidal microplate is its core key technology. However, it has the following disadvantages:

[0006] 1. Reusability. In the current development trend of detection technology, from sample addition to the experimental process, in order to avoid cross contamination, disposable experimental plates (wells) are basically used. However, as for the blood type ladder microplate, due to its high cost, one plate costs more than a thousand yuan, forcing people to wash and use it repeatedly.

[0007] 2. High precision is an advantage in itself. Judging from the current global usage, its precision to the cell diameter depends on the most primitive manual cleaning and disinfection. The quality of cleaning and disinfection is greatly reduced, which directly affects the precision of the plate and the operating quality of the entire system.

[0008] 3. Manual operation of cleaning and disinfection. At present, the water in the board is manually shaken off and then dried, which is time-consuming and labor-intensive, and the quality cannot be guaranteed. Although relevant countries have developed board washing machines, the huge cost of 700,000 to 800,000 yuan is too high to be expected, and it does not have a complete disinfection function and cannot be widely used.

[0009] 4. Biosafety issues. With the current processing method, manual flushing and disinfection in an open space will inevitably cause the generation of aerosols and droplets, which will affect the serum and blood cells in the microplate, causing biosafety issues.

[0010] Therefore, in order to solve the above technical problems, it is urgent to propose a new technical means to solve them. Summary of the invention

[0011] In view of this, the purpose of the present invention is to provide a fully automatic biological laboratory vessel cleaning, disinfection and air-drying system, which can automatically and closed clean, disinfect and air-dry biological laboratory vessels such as blood type gradient plates and nucleic acid racks, effectively avoid human contact during the cleaning and disinfection process, prevent cross infection, and ensure biological safety in the laboratory.

[0012] The present invention provides a fully automatic biological experiment vessel cleaning, disinfection and air drying system, comprising a cleaning and disinfection box, a support frame, a vessel support and a disinfection and cleaning mechanism;

[0013] The vessel support is arranged in a cleaning and disinfecting box, and the cleaning and disinfecting box is fixedly arranged on a supporting frame;

[0014] The disinfection and cleaning mechanism comprises an upper spray cleaning component, a lower spray cleaning component and a spray cleaning component mounting mechanism;

[0015] The upper spray washing assembly is fixedly arranged on the spray washing assembly mounting mechanism, and the lower spray washing assembly is arranged on the spray washing assembly mounting mechanism and can reciprocate longitudinally. The spray washing assembly mounting mechanism drives the upper spray washing assembly and the lower spray washing assembly to reciprocate laterally at the same time, and the upper spray washing assembly and the lower spray washing assembly have opposite spraying directions.

[0016] Further, the upper spray washing assembly and the lower spray washing assembly have the same structure;

[0017] The upper spray assembly and the lower spray assembly both have a water-gas nozzle and a water-gas nozzle mounting seat. The water-gas nozzle is fixedly arranged on the water-gas nozzle mounting seat and is connected to the water-gas nozzle mounting seat. There are multiple water-gas nozzles and they are arranged at equal intervals along the length direction of the water-gas nozzle mounting seat. The input port of the water-gas nozzle mounting seat is connected to the cleaning and disinfection medium supply equipment.

[0018] Further, the spray assembly mounting mechanism includes a transverse guide rail, a slider, a longitudinal guide rail, a first mounting plate and a second mounting plate;

[0019] The transverse guide rail is fixedly arranged on the support frame and is located outside the cleaning and disinfection box, the slider is slidably arranged on the transverse guide rail, the longitudinal guide rail is fixedly arranged on the slider and the longitudinal guide rail is perpendicular to the transverse guide rail, the first mounting plate is fixedly arranged on the longitudinal guide rail, and the first mounting plate is installed with an upper spray assembly, the second mounting plate is slidably arranged on the longitudinal guide rail, and the second mounting plate is installed with a lower spray assembly.

[0020] Further, the spray assembly installation mechanism also includes a first drive motor, a first lead screw pair, a second drive motor and a second lead screw pair;

[0021] The first drive motor and the first screw pair are arranged on the transverse guide rail, the power output end of the first drive motor is transmission connected with the power input end of the screw pair, the first screw pair drives the slider to move, the second drive motor and the second screw pair are arranged in longitudinal conduction, the power output end of the second drive motor is transmission connected with the power input end of the second screw pair, and the second screw pair drives the second mounting plate to slide longitudinally.

[0022] Furthermore, the vessel support is formed by arranging a plurality of vessel support units in parallel;

[0023] The vessel support unit comprises a support plate, a U-shaped support and a vessel support, wherein the U-shaped opening of the U-shaped support faces the horizontal direction, the support plate is fixedly arranged on the upper side of the U-shaped support, and the vessel support is in multiple and equidistantly arranged on the support plate.

[0024] Further, the cleaning and disinfecting medium supply equipment includes a gas compressor, a booster pump and a liquid cleaning and disinfecting medium container;

[0025] The output ends of the gas compressor and the booster pump are connected to the input port of the water and gas nozzle mounting seat through a three-way joint, and the input end of the booster pump is connected to the liquid cleaning and disinfecting medium container.

[0026] The beneficial effects of the present invention are as follows: through the present invention, biological experimental utensils such as blood type gradient plates and nucleic acid racks can be automatically and closedly cleaned, disinfected and air-dried, and human contact can be effectively avoided during the cleaning and disinfection process to prevent cross infection and ensure biological safety in the laboratory. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The present invention will be further described below in conjunction with the accompanying drawings and embodiments:

[0028] Figure 1 It is a structural schematic diagram of the present invention.

[0029] Figure 2 It is a schematic diagram of the structure of the support frame and the cleaning, disinfection and air-drying mechanism of the present invention.

[0030] Figure 3 for Figure 2 Another diagram of the directional structure diagram.

[0031] Figure 4 It is a schematic diagram of the structure of the vessel support unit of the present invention.

[0032] Figure 5 It is a schematic diagram of the pipeline structure of the present invention. DETAILED DESCRIPTION

[0033] The present invention is further described in detail below in conjunction with the accompanying drawings:

[0034] The present invention provides a fully automatic biological experiment vessel cleaning, disinfection and air drying system, comprising a cleaning and disinfection box, a support frame 6, a vessel support 3 and a disinfection cleaning and air drying mechanism; wherein the cleaning and disinfection box comprises a box body 1 and a box cover 4, such as Figure 1 As shown;

[0035] The vessel support 3 is arranged in a cleaning and disinfecting box, and the cleaning and disinfecting box is fixedly arranged on a support frame;

[0036] The disinfection and cleaning mechanism comprises an upper spray cleaning component 7, a lower spray cleaning component 8 and a spray cleaning component mounting mechanism;

[0037] The upper spray assembly 7 is fixedly arranged on the spray assembly installation mechanism, and the lower spray assembly 8 is arranged on the spray assembly installation mechanism and can reciprocate in the longitudinal direction. The spray assembly installation mechanism drives the upper spray assembly and the lower spray assembly to reciprocate in the transverse direction at the same time. The upper spray assembly and the lower spray assembly spray in opposite directions. Figure 1 As shown, the cleaning and disinfecting medium of the upper spray assembly is sprayed downward, and the cleaning and disinfecting medium of the lower spray assembly is sprayed upward. Through the structure of the present invention, biological experimental vessels such as blood type gradient plates can be automatically and closed for cleaning, disinfection, and air-drying. Human contact can be effectively avoided during the cleaning, disinfection, and air-drying process, thereby effectively preventing cross-infection of the human body and effectively ensuring the safety of biological samples. In order to facilitate the transportation of the entire equipment, walking wheels 18 are also provided on the bracket.

[0038] In this embodiment, the upper spray washing assembly 7 and the lower spray washing assembly 8 have the same structure;

[0039] The upper spray assembly 7 and the lower spray assembly 8 both have a water-gas nozzle 9 and a water-gas nozzle mounting seat 2, wherein the water-gas nozzle is fixedly arranged on the water-gas nozzle mounting seat and is connected to the water-gas nozzle mounting seat, wherein there are multiple water-gas nozzles and they are arranged at equal intervals along the length direction of the water-gas nozzle mounting seat, and an input port 10 of the water-gas nozzle mounting seat 2 is connected to a cleaning and disinfection medium supply device, wherein the interior of the water-gas nozzle mounting seat is a hollow structure for conveying liquid medium, gas or a mixture of liquid medium and gas to the water-gas nozzle, and through the above structure, vessels such as blood type gradient plates arranged on the vessel holder can be rinsed, disinfected and air-dried, and immersion disinfection can also be achieved through the box.

[0040] In this embodiment, the spray assembly mounting mechanism includes a transverse guide rail 17, a slider 16, a longitudinal guide rail 13, a first mounting plate 11 and a second mounting plate 14;

[0041] The transverse guide rail 17 is fixedly arranged on the support frame 6 and is located outside the cleaning and disinfection box, the slider 16 is slidably arranged on the transverse guide rail, the longitudinal guide rail 13 is fixedly arranged on the slider and the longitudinal guide rail is perpendicular to the transverse guide rail 17, the first mounting plate is fixedly arranged on the longitudinal guide rail, the first mounting plate is installed with an upper spray assembly, the second mounting plate is slidably arranged on the longitudinal guide rail, and the second mounting plate is installed with a lower spray assembly. Through the above structure, when the biological experimental vessel needs to be immersed and disinfected, the second mounting plate is controlled to slide upward, so that the lower spray assembly will not be immersed in the disinfection medium; wherein:

[0042] The spray assembly installation mechanism also includes a first drive motor 19, a first lead screw pair 15, a second drive motor 12 and a second lead screw pair 20;

[0043] The first drive motor and the first screw pair are arranged on the transverse guide rail, the power output end of the first drive motor is transmission-connected with the power input end of the screw pair, the first screw pair drives the slider to move, the second drive motor and the second screw pair are arranged in longitudinal conduction, the power output end of the second drive motor is transmission-connected with the power input end of the second screw pair, the second screw pair drives the second mounting plate to slide longitudinally, wherein the structure and driving principle of the screw pair are prior art and will not be described in detail here, through the above structure, on the one hand, the upper spray assembly and the lower spray assembly can be driven to move along the transverse direction at the same time The guide rail moves, thereby realizing horizontal scanning spray washing, disinfection and air drying of the utensils in the cleaning and disinfection box, and because the spraying directions of the upper spray head and the lower spray head are opposite, the cleaning direction is comprehensive and the cleaning is more thorough. On the other hand, the second drive motor drives the second screw pair to move, thereby realizing the longitudinal reciprocating motion of the second mounting plate, so that when immersion disinfection is carried out, the second mounting plate is controlled to slide upward, so that the lower spray washing assembly will not be immersed in the disinfection medium; the transmission connection in the above-mentioned can be directly connected through a coupling, and can also be realized through an existing reducer.

[0044] In this embodiment, the vessel support 3 is formed by a plurality of vessel support units arranged in parallel;

[0045] The vessel holder unit includes a support plate 31, a U-shaped holder 33 and a vessel holder 32. The U-shaped opening of the U-shaped holder 33 faces the horizontal direction. Of course, the U-shaped opening of the U-shaped holder 33 of each vessel holder unit faces the same direction. The support plate is fixedly arranged on the upper side of the U-shaped holder. There are multiple vessel holders arranged on the support plate at equal intervals. Through the above structure, multiple test vessels such as blood type gradient plates can be placed. On the other hand, due to the effect of the U-shaped holder, there is a gap between the vessel holder and the bottom of the box, thereby avoiding obstruction to the lower spray assembly during the horizontal scanning spray process.

[0046] In this embodiment, the cleaning, disinfection and medium supply equipment includes a gas compressor 21, a booster pump 26 and a liquid cleaning and disinfection medium container 25;

[0047] The output ends of the gas compressor 21 and the booster pump 26 are connected to the input port of the water and gas nozzle mounting base 2 through three-way connectors (23, 24, 28, 29), and the input end of the booster pump is connected to the liquid cleaning and disinfection medium container. The specific connection method is as follows: Figure 5 As shown, a first solenoid valve 22 is provided at the output end of the booster pump, and a second solenoid valve 27 is provided at the output end of the gas compressor to control the flow of gas and liquid cleaning and disinfection media. In order to ensure that the upper spray washing component and the lower spray washing component can have gas and liquid media at the same time, a plurality of three-way valves are also provided on the pipeline, such as Figure 5As shown; of course, in order to display the corresponding parameters of the disinfection and cleaning process, a display controller 5 is also provided, which is used to control the rotation speed of the first drive motor, the second drive motor and the opening and closing of the first solenoid valve and the second solenoid valve, and a liquid level detector is provided in the box body, which is used to monitor the amount of liquid cleaning and disinfection medium in the box body and display it through the display controller. In order to ensure the reciprocating motion of the slider and the second mounting plate, the first drive motor and the second drive motor adopt existing forward and reverse motors.

[0048] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the present invention, which should be included in the scope of the claims of the present invention.

Claims

1. A fully automatic biological experiment vessel cleaning, disinfection and air drying system, characterized by: It includes a cleaning and disinfection box, a support frame, a vessel support, and a disinfection, cleaning and air-drying mechanism; The vessel support is arranged in a cleaning and disinfecting box, and the cleaning and disinfecting box is fixedly arranged on a supporting frame; The disinfection, cleaning and air-drying mechanism comprises an upper spray-washing assembly, a lower spray-washing assembly and a spray-washing assembly mounting mechanism; The upper spray assembly is fixedly arranged on the spray assembly installation mechanism, the lower spray assembly is arranged on the spray assembly installation mechanism and can reciprocate in the longitudinal direction, the spray assembly installation mechanism drives the upper spray assembly and the lower spray assembly to reciprocate in the transverse direction at the same time, and the upper spray assembly and the lower spray assembly spray in opposite directions; The spray assembly mounting mechanism includes a transverse guide rail, a slider, a longitudinal guide rail, a first mounting plate and a second mounting plate; The transverse guide rail is fixedly arranged on the support frame and is located outside the cleaning and disinfection box, the slider is slidably arranged on the transverse guide rail, the longitudinal guide rail is fixedly arranged on the slider and the longitudinal guide rail is perpendicular to the transverse guide rail, the first mounting plate is fixedly arranged on the longitudinal guide rail, the first mounting plate is installed with an upper spray assembly, the second mounting plate is slidably arranged on the longitudinal guide rail, and the second mounting plate is installed with a lower spray assembly; The vessel support is formed by arranging a plurality of vessel support units in parallel; The vessel support unit comprises a support plate, a U-shaped support and a vessel support, wherein the U-shaped opening of the U-shaped support faces the horizontal direction, the support plate is fixedly arranged on the upper side of the U-shaped support, and the vessel support is in multiple and equidistantly arranged on the support plate.

2. The fully automatic biological experiment vessel cleaning, disinfection and air drying system according to claim 1, characterized in that: The upper spray washing assembly and the lower spray washing assembly have the same structure; The upper spray assembly and the lower spray assembly both have a water-gas nozzle and a water-gas nozzle mounting seat. The water-gas nozzle is fixedly arranged on the water-gas nozzle mounting seat and is connected to the water-gas nozzle mounting seat. There are multiple water-gas nozzles and they are arranged at equal intervals along the length direction of the water-gas nozzle mounting seat. The input port of the water-gas nozzle mounting seat is connected to the cleaning, disinfection and air-drying medium supply equipment.

3. The fully automatic biological experiment vessel cleaning, disinfection and air drying system according to claim 1, characterized in that: The spray assembly installation mechanism also includes a first drive motor, a first lead screw pair, a second drive motor and a second lead screw pair; The first drive motor and the first screw pair are arranged on the transverse guide rail, the power output end of the first drive motor is transmission connected with the power input end of the screw pair, the first screw pair drives the slider to move, the second drive motor and the second screw pair are arranged in longitudinal conduction, the power output end of the second drive motor is transmission connected with the power input end of the second screw pair, and the second screw pair drives the second mounting plate to slide longitudinally.

4. The fully automatic biological experiment vessel cleaning, disinfection and air drying system according to claim 2, characterized in that: The cleaning, disinfecting and air-drying medium supply equipment includes a gas compressor, a booster pump and a liquid cleaning and disinfecting medium container; The output ends of the gas compressor and the booster pump are connected to the input port of the water and gas nozzle mounting seat through a three-way joint, and the input end of the booster pump is connected to the liquid cleaning and disinfecting medium container.

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