Automatic glass plate washer for immunoblotting

Abstract

The present invention relates to an automatic glass plate cleaning machine for immunoblotting test, comprising a body, a cleaning device arranged on the body, the cleaning device comprising a conveyor belt and a cleaning mechanism arranged along the conveyor belt, a glass plate positioning tooling for positioning a glass plate arranged on the conveyor belt, a glass plate soaking device also arranged on the body, the glass plate soaking device comprising a glass plate placement bin with a plurality of glass plate shelves and a soaking chamber for immersing the glass plates in the glass plate placement bin, the glass plate placement bin being matched with a feeding mechanism for transferring the glass plates on the glass plate shelves to the glass plate positioning tooling of the conveyor belt. The glass plates are soaked in advance and then automatically cleaned, which has the advantages of simple and convenient operation and clean cleaning.

Description

Technical Field

[0001] The invention relates to biological laboratory auxiliary equipment, in particular to equipment for automatically cleaning glass plates used in immunoblotting tests. Background Art

[0002] Western Blot is a commonly used experimental method in molecular biology, biochemistry and immunogenetics. Its basic principle is to stain cells or biological tissue samples treated by gel electrophoresis with specific antibodies. By analyzing the position and depth of staining, information on the expression of specific proteins in the analyzed cells or tissues can be obtained. Experiments often require multi-plate gel electrophoresis to be carried out simultaneously, and the cleanliness of the glass plate is extremely strict when making gels, so the glass plates used in the experiment need to be fully cleaned. The commonly used method is to wipe them one by one with laundry detergent or alcohol, rinse them with a large amount of water, wash them with distilled water, and dry them for use. Manual operation is cumbersome, which wastes the precious time of experimental operators, and improper operation can easily damage the glass plate.

[0003] For this purpose, there is a technology designed to automatically clean the glass, such as the "Glass Plate Cleaning Device for Protein Blotting Method" disclosed in the patent document with Chinese patent application number CN 201910256959.4, which uses a conveyor belt with multiple clamping tools set in the box, clamps the glass plate on the tools and moves it through the conveyor belt, and arranges cleaning nozzles and cleaning strips along the conveyor belt to clean the glass plate. Because the gel on the glass plate adheres more firmly and is not easy to clean, the above cleaning requires the glass plate to be clamped and fixed firmly and then cleaned with greater force, and there is a low degree of automation, and the cleaning operation process is inconvenient. Summary of the invention

[0004] Purpose of the invention: To overcome the defects of the prior art, the present invention provides an automatic glass plate cleaning machine for immunoblotting test which can automatically clean the glass plate after soaking it in advance, and has the advantages of simple and convenient operation and clean cleaning.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an automatic glass plate cleaning machine for immunoblotting test, comprising a body, a cleaning device is provided on the body, the cleaning device comprises a conveyor belt and a cleaning mechanism arranged along the conveyor belt, a glass plate positioning tooling for positioning the glass plate is arranged on the conveyor belt, and the characteristic is that: a glass plate immersion device is also provided on the body, the glass plate immersion device comprises a glass plate placement bin with a plurality of glass plate shelves and a immersion chamber for immersing the glass plate in the glass plate placement bin, the glass plate placement bin is matched with a feeding mechanism on the glass plate positioning tooling for transferring the glass plate on the glass plate shelf to the conveyor belt.

[0006] By adopting the above technical solution, the glass plate is soaked in advance before cleaning, and the gel on the glass plate is softened, thereby facilitating the subsequent cleaning operation of the glass plate. The gel on the glass plate is easier to be thoroughly cleaned, and the feeding mechanism automatically transfers the glass plate to the tooling of the conveyor belt, which is more automated and more convenient to operate.

[0007] Preferably, the glass plate placement bin is lifted and matched in the machine body, and the feeding mechanism includes a soaking bin lifting drive mechanism for driving the glass plate placement bin to lift and lower, and the machine body is provided with a discharge station, a soaking station and a feeding station in sequence along the lifting direction of the glass plate placement bin. The glass plate placement bin is located at the front end of the conveyor belt cleaning process, and the glass plate shelf rack is inclined downwardly towards one end of the conveyor belt in a slope shape. The low end of the glass plate shelf rack is a slide-out end for the glass plate to slide out, and the high end of the glass plate shelf rack is an insertion end for the glass plate to be inserted into the glass plate shelf rack. The glass plate placement bin includes a frame-shaped main body, the frame-shaped main body has a bottom and closed side panels located on both sides of the glass plate shelf rack in the horizontal direction, the frame-shaped main body is matched with a sealing gate plate corresponding to the slide-out end of the glass plate shelf rack, and the sealing gate plate is sealed and plugged into the frame-shaped main body along the lifting direction of the glass plate placement bin, and the machine body A blocking part is provided inside to block the sealing gate from following the glass plate placing bin to descend to the feeding station. The sealing gate is blocked by the blocking part during the process of the glass plate placing bin descending from the immersion station to the feeding station, so that the glass plate placing bin exposes the sliding-out end of the glass rod shelf rack. The glass plate shelf rack corresponds to the glass plate sliding along the sliding-out end of the glass plate shelf rack into the glass plate positioning fixture of the conveyor belt during the feeding process, and as the conveyor belt moves to complete the sliding and positioning of the glass plate on the glass plate positioning fixture, the sealing gate rises with the glass plate placing bin to the discharging station, and a sealing bin door corresponding to the immersion station is provided in the machine body for closing a side opening corresponding to the feeding end of the glass plate placing bin located at the immersion station, the inner cavity of the glass plate placing bin located at the immersion station is enclosed by the sealing bin door and the sealing gate to form the immersion chamber, and the immersion chamber is provided with a liquid injection port and a liquid discharge port. Under this structural design, when the glass plate placing bin is located at the unloading station, the sealing gate follows the glass plate placing bin to close the sliding-out end, and the operator places the glass plate along the putting-in end onto the glass plate shelf rack located in the glass plate placing bin, and the glass plate placing bin with the glass plate placed descends to enter the soaking process. At this time, the sealing bin door closes the putting-in end of the glass plate placing bin, thereby forming a soaking chamber, and the soaking chamber is injected with soaking liquid (such as water, alcohol, etc.). After the soaking is completed, the liquid in the soaking chamber is drained, the sealing bin door is opened, and the glass plate placing bin descends to enter the feeding station. At this time, the sealing gate is blocked by the blocking part, so that the sliding-out end of the glass plate shelf rack entering the feeding station in turn is exposed, and the glass plate can slide out and fall on the conveyor belt. As the conveyor belt moves, the glass plate is dragged until it finally falls completely on the glass plate positioning tooling of the conveyor belt, and the glass plate enters the cleaning process. The lifting and lowering of the glass plate placing bin is used to realize the carrying of the glass plate for unloading, soaking and feeding, which has the advantage of compact structure.

[0008] Preferably, the glass plate placement bin has a reset process for automatically resetting to the soaking station after the glass plate racks have passed the feeding station, and the machine body is provided with a retaining part for retaining the sealing gate at the soaking station during the reset action of the glass plate placement bin. This structural design facilitates the next operation of the equipment.

[0009] Preferably, the sealed door is slidably fitted on the machine body in a direction facing the insertion end of the glass plate placement bin, and the sealed door is equipped with a door driver for driving the sealed door to slide. Under this structural design, the sealed door is positively buckled toward the glass plate placement bin, which has the advantage of reliable sealing.

[0010] Preferably, the glass plate positioning tool comprises a positioning and resting groove cavity with positioning walls on all sides, and a rubber pressing needle assembly is arranged at the four corner positions of the positioning and resting groove cavity, the rubber pressing needle assembly comprises a flexible rubber pressing needle and a needle seat for fixing the rubber pressing needle, the needle seat is slidably fitted on the conveyor belt along the width direction of the conveyor belt, and the rubber pressing needle can enter and exit the positioning and resting groove cavity as the needle seat slides, the rubber pressing needle is spaced from the bottom of the positioning and resting groove cavity for the glass plate to be inserted, the needle seat is equipped with a driving spring for driving the needle seat to move the rubber pressing needle into the positioning and resting groove cavity, the needle seat has a toggle end located on the side of the conveyor belt, and a toggle piece is arranged on the side of the machine body corresponding to the end of the conveyor belt that receives the glass plate, as the conveyor belt moves, the toggle end of the needle seat passes through the toggle piece and is toggled by the toggle piece to make the rubber pressing needle exit the positioning and resting groove cavity, the toggle piece corresponds to the position where the rubber pressing needle assembly located at the rear enters the glass plate, so as to facilitate the glass plate to fall into the positioning and resting groove cavity. Under this structural design, the rubber pressure pin can achieve flexible pressing of the glass plate. In the initial stage, the inclined glass plate is pressed by the rubber pressure pin so that the glass plate can be reliably dragged along with the conveyor belt. In the cleaning stage, the rubber pressure pin can press and hold the glass plate.

[0011] Preferably, the conveyor belt is formed into a ring shape by splicing a plurality of chain plates, and the middle part of the chain plates between adjacent positioning and shelving grooves is hollowed out. The cleaning mechanism includes an initial wiping roller strip, a flushing nozzle, a secondary wiping roller strip, a cleaning nozzle and a water removal roller strip arranged in sequence along the moving direction of the conveyor belt. The flushing nozzle and the cleaning nozzle are both oriented toward the direction of the conveyor belt cleaning starting position. The flushing nozzle and the cleaning nozzle are equipped with a cleaning liquid storage box, and a water receiving tray is provided in the middle of the conveyor belt. Under this structural design, the glass plate is well cleaned after at least two scrubbings, and the flushing nozzle flushes and cleans toward the front wiping roller, which can flush the impurities under the scrubbing and discharge them through the hollowing on the conveyor belt. The water receiving tray can receive the cleaning liquid and impurities flowing out of the hollowing to prevent the impurities from contaminating the conveyor belt. The water removal roller strip cleans the accumulated water on the cleaned glass plate.

[0012] Preferably, the machine body is rotatably provided with a first roller bar mounting arm and a second roller bar mounting arm, the initial wiping roller bar is detachably mounted on one end of the first roller bar mounting arm, a spare initial wiping roller bar is detachably mounted on the other end of the first roller bar mounting arm, the secondary wiping roller bar is detachably mounted on one end of the second roller bar mounting arm, a spare secondary wiping roller bar is detachably mounted on the other end of the second roller bar mounting arm, the first roller bar mounting arm and the second roller bar mounting arm are connected with a rotation driving mechanism for driving the first roller bar mounting arm and the second roller bar mounting arm to rotate, and a disassembly operation window for exposing the spare initial wiping roller bar and the spare secondary wiping roller bar is provided on the machine body. Under this structural design, both the initial wiping roller bar and the secondary wiping roller bar have spare roller bars that can be used in rotation, which is more convenient to use, and the disassembly operation window facilitates the replacement of the spare roller bars.

[0013] Preferably, the conveyor belt is connected to a glass plate drying device at the end of the washing process, and the glass plate drying device includes a glass plate receiving bin for receiving the glass plates washed on the conveyor belt, and a drying chamber for drying the glass plates in the glass plate receiving bin is provided on the machine body. With this structural design, the glass plates washed on the conveyor belt are automatically stored and dried for next use.

[0014] Preferably, the glass plate drying device comprises a glass plate receiving bin which is lifted and matched on the machine body, a receiving bin lifting drive mechanism for driving the glass plate receiving bin to lift and lower, and a drying box. The glass plate receiving bin is located at the end position of the washing process of the conveyor belt. The glass plate receiving bin comprises a frame-shaped receiving bin main body. A plurality of receiving racks for placing glass plates are longitudinally distributed in the receiving bin main body. The receiving racks are arranged obliquely upward in the direction toward the conveyor belt. The receiving bin main body has a glass plate sliding entrance facing the conveyor belt, a closed back plate and a bottom plate opposite to the glass plate sliding entrance. A sealed bottom cover plate is magnetically attached to the bottom plate of the receiving bin main body. The machine body is provided with a drying A drying station is provided with a U-shaped box plate at the drying station, and a hot air outlet is provided on the U-shaped box plate. A hot air generating device for supplying hot air through the hot air outlet is provided on the machine body. When the glass plate receiving bin enters the drying process, it is inserted into the U-shaped box plate and is laterally closed by the U-shaped box plate, so that the glass plate receiving bin is surrounded by the U-shaped box plate and the closed back plate to form a cylindrical drying chamber during the drying process. The sealed bottom cover plate contacts and covers the bottom of the U-shaped box plate, thereby closing the bottom of the cylindrical drying chamber, and a magnetic attraction part that cooperates with the sealed bottom magnetic attraction is provided at the bottom of the U-shaped box plate. The machine body is provided with a bin cover that can open and close the top opening of the cylindrical drying chamber, and the glass plate receiving bin can rise and pass through the top opening of the U-shaped box plate. With this structural design, the glass plate receiving bin moves upward to receive the cleaned glass plates output by the conveyor belt in sequence, and the glass plates slide onto the receiving rack. When the glass plate receiving bin rises to the drying position, the glass plate receiving bin is inserted into the U-shaped box plate, and a closed drying chamber is formed by the sealed bottom cover plate, bin cover, closed back plate and bottom plate of the glass plate receiving bin, and hot air is injected into the drying chamber through the hot air outlet to achieve drying and storage of the glass plates. When needed, the bin cover is opened, the glass plate receiving bin is moved out of the top opening of the U-shaped box plate, and the glass plate sliding entrance is exposed, so that the glass plates can be easily taken out, and the sealed bottom cover plate is restricted at the bottom of the U-shaped box plate. When the glass plate receiving bin descends, the sealed bottom cover plate can be pushed and fixed by magnetic attraction. It has the advantages of simple and compact structure.

[0015] Preferably, the machine body has an electronic device assembly chamber separated from the area where the cleaning device, the glass plate soaking device and the glass plate drying device are located. Under this structural design, the main electronic devices are assembled separately to ensure stable and reliable operation of the equipment.

[0016] The present invention will be further described below in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the structure of an automatic glass plate cleaning machine for immunoblotting test according to a specific embodiment of the present invention;

[0018] Figure 2 This is a schematic diagram of the internal structure of an automatic glass plate cleaning machine for immunoblotting test according to a specific embodiment of the present invention;

[0019] Figure 3 It is a structural schematic diagram of a glass plate soaking device according to a specific embodiment of the present invention in a state where a glass plate to be cleaned is placed therein;

[0020] Figure 4 It is a structural schematic diagram of a glass plate soaking device in a specific embodiment of the present invention in a feeding state;

[0021] Figure 5 It is a structural schematic diagram of a glass plate drying device in a specific embodiment of the present invention in a state where a glass plate is provided for use;

[0022] Figure 6 It is a structural schematic diagram of a glass plate drying device according to a specific embodiment of the present invention in a state where a glass plate is provided to receive a glass plate on a conveyor belt;

[0023] Figure 7 This is a schematic structural diagram of a machine body in a specific embodiment of the present invention when the electronic device assembly cavity is open;

[0024] Figure 8 for Figure 2 A partial enlarged view of part A. DETAILED DESCRIPTION

[0025] See attached Figures 1 to 8 The present invention discloses an automatic glass plate cleaning machine for immunoblotting test, comprising a body 1, a cleaning device 2 is arranged on the body 1, the cleaning device 2 comprises a conveyor belt 21 and a cleaning mechanism arranged along the conveyor belt 21, a glass plate positioning tooling for positioning the glass plate 1 is arranged on the conveyor belt 21, and a glass plate soaking device 3 is also arranged on the body 1, the glass plate soaking device 3 comprises a glass plate placing bin 31 with a plurality of glass plate shelves 32 and a soaking chamber 30 for immersing the glass plate in the glass plate placing bin 31, and the glass plate placing bin 31 is matched with a feeding mechanism for transferring the glass plate on the glass plate shelf 32 to the glass plate positioning tooling on the conveyor belt 21. Before the glass plate is cleaned, the glass plate is soaked in advance, the gel on the glass plate is softened, so as to facilitate the subsequent cleaning operation of the glass plate, and the gel on the glass plate is easier to be thoroughly cleaned, and the feeding mechanism automatically transfers the glass plate to the tooling on the conveyor belt 21, which is more automated and more convenient to operate.

[0026] The glass plate placement bin 31 is lifted and matched in the machine body 1, a track is provided in the machine body 1, a matching track that matches the track is provided on the glass plate placement bin 31, the feeding mechanism includes an immersion bin lifting drive mechanism 33 that drives the glass plate placement bin 31 to lift and lower, and the machine body 1 has a discharge station, an immersion station and a feeding station in sequence along the lifting direction of the glass plate placement bin 31. The glass plate placement bin 31 is located at the front end of the conveyor belt 21 cleaning process, and the glass plate shelf 32 is inclined downward toward one end of the conveyor belt 21 in a slope shape. In order to slide out the glass plate better, the glass plate shelf 32 adopts rollers to support the glass plate, the low end of the glass plate shelf 32 is a slide-out end 321 for the glass plate to slide out, and the high end of the glass plate shelf 32 is for the glass plate to be inserted into the glass plate shelf 32 The glass plate placing bin 31 comprises a frame-shaped main body 311, the frame-shaped main body 311 has a bottom 312 and closed side panels 313 located on both sides of the glass plate shelf 32, the frame-shaped main body 311 is matched with a sealing gate 34 corresponding to the slide-out end 321 of the glass plate shelf 32, the sealing gate 34 is sealed and plugged on the frame-shaped main body 311 along the lifting direction of the glass plate placing bin 31, and a blocking part (not shown in the figure, which can be fixed on a convex plate in the body) is provided in the machine body 1 to block the sealing gate 34 from following the glass plate placing bin 31 to descend to the feeding station, and the sealing gate 34 is blocked by the blocking part during the process of the glass plate placing bin 31 descending from the immersion station to the feeding station, so that the glass plate placing bin 31 is exposed to the slide-out end 321 of the glass rod shelf (such as Figure 4The glass plate placement bin 31 is located at the position of the glass plate placement bin 31 shown in the figure), and the glass plate shelf 32 corresponds to the glass plate sliding into the glass plate positioning fixture of the conveyor belt 21 along the sliding-out end 321 of the glass plate shelf 32 during the feeding process, and as the conveyor belt 21 moves to complete the sliding of the glass plate 1 into the glass plate positioning fixture, the sealing gate 34 rises with the glass plate placement bin 31 to the discharging station, and a sealing bin door 35 corresponding to the immersion station is provided in the machine body 1 for closing a side opening corresponding to the feeding end 322 of the glass plate placement bin 31 located at the immersion station, and the sealing bin door 35 and the sealing gate 34 are used to seal the glass plate placement bin 31 located at the immersion station. The inner cavity of the glass plate placement bin 31 forms the immersion chamber 30, and the sealing surface of the sealed bin door 35 is pressed against the frame of the glass plate placement bin 31 to achieve a reliable seal. The specific sealing structure is a conventional technology in the field, so it is not described in detail. The immersion chamber 30 is equipped with a liquid injection port 300 and a liquid discharge port 301. The liquid injection port 300 can lead to a dedicated water tank, and the liquid discharge port can lead to the outside. The liquid injection port 300 and the liquid discharge port 301 are both arranged on the sealed bin door 35. It is well known to those skilled in the art that in order to make the pipes connecting the liquid injection port and the liquid discharge port adapt to the movement of the sealed bin door 35, a telescopic joint is used on the pipe to achieve this. When the glass plate placement bin 31 is located at the unloading station, the sealing gate 34 follows the glass plate placement bin 31 to close the sliding end 321, and the operator places the glass plate along the insertion end 322 onto the glass plate shelf 32 located in the glass plate placement bin 31. The glass plate placement bin 31 with the glass plate placed descends to enter the soaking process. At this time, the sealing bin door 35 closes the insertion end 322 of the glass plate placement bin 31, thereby forming a soaking chamber 30. Soaking liquid (such as water, alcohol, etc.) is injected into the soaking chamber 30. After the soaking is completed, the liquid in the soaking chamber 30 is drained, and the sealing bin door 35 is opened. The glass plate is placed The bin 31 descends and enters the feeding station. At this time, the sealing gate 34 is blocked by the blocking part, so that the sliding end 321 of the glass plate shelf 32 that enters the feeding station in turn is exposed, and the glass plate can slide out and fall on the conveyor belt 21. As the conveyor belt 21 moves, the glass plate is dragged until it finally falls completely on the glass plate positioning tooling of the conveyor belt 21. The glass plate enters the cleaning process. The sealing gate 34 achieves sealing and blocks the glass plate, thereby controlling the sliding out and feeding of the glass plate. The lifting and lowering of the glass plate placement bin 31 is used to realize the carrying, discharging, soaking and feeding of the glass plate, which has the advantage of compact structure.

[0027] The sealed chamber door 35 is slidably fitted on the machine body 1 in the direction of the placement end 322 facing the glass plate placement chamber 31, and the sealed chamber door 35 is equipped with a chamber door driver 35-1 that drives the sealed chamber door 35 to slide. The sealed chamber door 35 is buckled toward the glass plate placement chamber 31 in a positive direction, which has the advantage of reliable sealing. The chamber door driver 35-1 adopts a push electric cylinder, and the driving shaft of the push electric cylinder is matched with a push spring in the push direction of the sealed chamber door 35, so that the spring force of the push spring can press the sealed chamber door to the glass plate placement chamber 31. Of course, as is well known to those skilled in the art, there are many other structures for driving devices that drive objects to move in a straight line, so all technical solutions of the driver that can drive the sealed chamber door to move in a straight line fall within the protection scope of the present invention.

[0028] In order to ensure that the equipment is convenient and reliable when in use, the glass plate placement bin 31 has a reset process that automatically resets to the soaking station after the glass plate shelf 32 passes through the feeding station. The body 1 is provided with a retaining portion that keeps the sealing gate 34 at the soaking station when the glass plate placement bin 31 is reset. This is convenient for the next operation of the equipment. In addition, in order to reliably reinsert the sealing gate 34 into the glass plate placement bin 31, a blocker can usually be provided above the sealing gate 34, such as a blocking tongue controlled by an electromagnet, or the upper end of the sealing gate 34 can be blocked by the top cover 36 on the body 1 that covers the top opening of the soaking chamber 30, and an electronic locking structure can be configured so that the top cover can be opened only when the glass plate shelf 32 is reset to the soaking station.

[0029] The glass plate positioning tool comprises a positioning and placing groove cavity 2-1 having positioning walls on all sides, and a rubber pressure needle assembly 2-2 is arranged at the four corners of the positioning and placing groove cavity 2-1. The rubber pressure needle assembly 2-2 comprises a flexible rubber pressure needle 2-21 and a needle seat 2-22 for fixing the rubber pressure needle 2-21. The needle seat 2-22 is slidably fitted on the conveyor belt 21 along the width direction of the conveyor belt 21. The rubber pressure needle 2-21 can enter and exit the positioning and placing groove cavity 2-1 by sliding with the needle seat 2-22. The rubber pressure needle 2-21 is spaced from the bottom of the positioning and placing groove cavity 2-1 for the glass plate to be inserted. The needle seat 2-22 is equipped with a driving needle seat 2-22 to move the rubber pressure needle 2-21 to the rubber pressure needle 2-21. A driving spring is provided for moving into the positioning and resting groove 2-1, and the needle seat 2-22 has a toggle end 2-221 located on the side of the conveyor belt 21. A toggle piece is provided on the side of the body 1 corresponding to the end of the conveyor belt 21 that receives the glass plate. As the conveyor belt 21 moves, the toggle end 2-221 of the needle seat 2-22 passes through the toggle piece and is toggled by the toggle piece so that the rubber pressure needle 2-21 withdraws from the positioning and resting groove 2-1. A toggle piece or an inclined surface can be provided on the toggle end 2-221 to realize the pushing and toggling of the needle seat 2-22. The toggle piece corresponds to the position where the glass plate falls into the rubber pressure needle assembly 2-2 at the rear, so as to facilitate the glass plate to fall into the positioning and resting groove 2-1. The rubber pressing needle 2-21 realizes flexible pressing and fixing of the glass plate. In the initial stage, the glass plate that slides in is inserted into the rubber pressing needle 2-21 and the bottom of the positioning and placing groove cavity 2-1 under the action of inertia. The inclined glass plate is pressed by the rubber pressing needle 2-21 so that the glass plate can be reliably dragged with the conveyor belt 21. An intermediate receiving roller is provided on the machine body 1 between the belt surface of the conveyor belt 21 and the sliding end 321 of the glass plate. During the cleaning stage, the rubber pressing needle 2-21 can press and fix the glass plate.

[0030] In the present invention, the conveyor belt 21 is connected to a glass plate drying device 5 at the end of the cleaning process, and the glass plate drying device 5 includes a glass plate receiving bin 51 for receiving the glass plate 1 cleaned on the conveyor belt 21, and the machine body 1 is provided with a drying chamber 50 for drying the glass plate in the glass plate receiving bin 51. The cleaned glass plate on the conveyor belt 21 is automatically stored and dried for next use.

[0031] The glass plate receiving bin 51 is lifted and matched on the machine body 1. The glass plate receiving bin 51 is matched with a receiving bin lifting driving mechanism 52 for driving the glass plate receiving bin 51 to lift. The glass plate receiving bin 51 is located at the end of the cleaning process of the conveyor belt 21. The glass plate receiving bin 51 includes a frame-shaped receiving bin main body 511. A plurality of receiving racks 512 for placing glass plates are longitudinally distributed in the receiving bin main body 511. The receiving racks 512 are arranged obliquely upward in the direction toward the conveyor belt 21. The receiving bin main body 511 has a glass plate sliding entrance 5111 facing the conveyor belt 21, a closed back plate 5112 and a bottom plate 5113 opposite to the glass plate sliding entrance 5111, and a sealed bottom cover plate 53 is magnetically attracted on the bottom plate 5113 of the receiving bin main body 511. The machine body 1 is provided with a drying station above the conveyor belt 21, and a U-shaped box plate 5 is provided at the drying station. 4. A hot air outlet 541 is provided on the U-shaped box plate 54, and a hot air generating device 56 (such as a hot air blower) for supplying hot air through the hot air outlet 541 is provided on the machine body 1. The hot air generating device is a device that can be directly purchased on the market, so its pipeline connection is not repeated. When the glass plate receiving bin 51 enters the drying process, it is inserted into the U-shaped box plate 54 and is laterally closed by the U-shaped box plate 54, so that the glass plate receiving bin 51 is surrounded by the U-shaped box plate 54 and the closed back plate 5112 to form a cylindrical drying chamber 50 during the drying process. The sealed bottom cover plate 53 contacts and covers the bottom of the U-shaped box plate 54, thereby closing the bottom of the cylindrical drying chamber 50, and a magnetic attraction member that magnetically cooperates with the sealed bottom 312 is provided at the bottom of the U-shaped box plate 54. The machine body 1 is provided with a bin cover 55 that can open and close the top opening of the cylindrical drying chamber 50, and the glass plate receiving bin 51 can rise and pass through the top opening of the U-shaped box plate 54 (such as Figure 5 As shown). The glass plate receiving bin 51 rises and moves to sequentially receive the cleaned glass plates output by the conveyor belt 21, and the glass plates slide onto the receiving rack 512. When the glass plate receiving bin 51 rises to the drying position, the glass plate receiving bin 51 is inserted into the U-shaped box plate 54, and the sealed bottom cover plate 53, the bin cover 55, the closed back plate of the glass plate receiving bin 51, and the bottom plate 5113 are surrounded to form a closed drying chamber 50, and hot air is injected into the drying chamber 50 through the hot air outlet 541 to dry and store the glass plates; when needed, the bin cover 55 is opened, the glass plate receiving bin 51 is moved out of the top opening of the U-shaped box plate 54, and the glass plate sliding entrance 5111 is exposed, so that the glass plates can be taken out conveniently, and the sealed bottom cover plate 53 is restricted at the bottom of the U-shaped box plate 54. When the glass plate receiving bin 51 descends, the sealed bottom cover plate 53 can be pushed and fixed by magnetic attraction; it has the advantages of simple and compact structure. In order to facilitate the glass plate to be released from the positioning and placing groove cavity 2-1, a shifting piece is also provided at the corresponding position of the cleaning end of the conveyor belt 21 to release the rubber pressing needle 2-21 from pressing the glass plate.

[0032] To further ensure reliable cleaning, the conveyor belt 21 is formed into a ring by splicing a number of chain plates 211, that is, the conveyor belt 21 is a chain conveyor belt 21. The chain conveyor belt 21 is a conventional technology in this field, so the specific chain plate 211 connection structure is not repeated. The middle part of the chain plate 211 between adjacent positioning and shelving grooves 2-1 is hollow 2111. The conveyor belt 21 assembled in the form of chain plates 211 is convenient for liquid to pass through and avoids water accumulation. The cleaning mechanism includes an initial wiping roller strip 22, a flushing nozzle 23, a secondary wiping roller strip 24, a cleaning nozzle 25 and a water removal roller strip 26 arranged in sequence along the movement direction of the conveyor belt 21. The flushing nozzle 23 and the cleaning nozzle 25 are both facing the direction of the cleaning starting position of the conveyor belt 21. The flushing nozzle 23 and the cleaning nozzle 25 are equipped with a cleaning liquid storage tank 27, and a water receiving tray 28 is provided in the middle of the conveyor belt 21. The glass plate is scrubbed at least twice to achieve good cleaning, and the flushing nozzle 23 flushes and cleans toward the front wiping roller, which can flush the impurities under the scrubbing and discharge them through the hollow 2111 on the conveyor belt 21. The water receiving tray 28 can receive the cleaning liquid and impurities flowing out of the hollow 2111 to prevent the impurities from contaminating the conveyor belt 21. The water removal roller strip 26 cleans the accumulated water on the cleaned glass plate. The water receiving tray 28 has a drainage hole. As known in the art, the initial wiping roller strip 22, the secondary wiping roller strip 24 and the water removal roller strip 26 are made of flexible materials such as rubber and sponge. At the same time, a side flushing nozzle can be added to better flush the back of the glass plate.

[0033] In order to improve the use efficiency, the machine body 1 is rotatably provided with a first roller bar mounting arm 22-1 and a second roller bar mounting arm 24-1. The initial wiping roller bar 22 is detachably mounted on one end of the first roller bar mounting arm 22-1, and a spare initial wiping roller bar 22-2 is detachably mounted on the other end of the first roller bar mounting arm 22-1. The secondary wiping roller bar 24 is detachably mounted on one end of the second roller bar mounting arm 24-1, and a spare secondary wiping roller bar 24-2 is detachably mounted on the other end of the second roller bar mounting arm 24-1. The first roller bar mounting arm 22-1 and the second roller bar mounting arm 24-1 are provided with a spare secondary wiping roller bar 24-2. The mounting arm 24-1 is connected with a rotation drive mechanism for driving the first roller mounting arm 22-1 and the second roller mounting arm 24-1 to rotate. The rotation drive mechanism can be realized by a motor driving the first roller mounting arm 22-1 and the second roller mounting arm 24-1, or by manually operating the first roller mounting arm 22-1 and the second roller mounting arm 24-1 to rotate (manual operation is adopted in this specific embodiment). The body 1 is provided with a disassembly operation window 12 for exposing the spare initial wiping roller 22-2 and the spare secondary wiping roller 24-2. Both the initial wiping roller 22 and the secondary wiping roller 24 have spare rollers that can be used in rotation, which is more convenient to use. The disassembly operation window facilitates the replacement of the spare rollers. The detachable mounting structure is a conventional technology in the art, such as snap-fitting, plug-in, hand-tightening bolt fixing (the method adopted in this specific embodiment), etc.

[0034] Since there is a large amount of liquid discharge in the cleaning device 2 area, a water tank 29 is usually set under the conveyor belt 21 to collect waste liquid and impurities in the cleaning process. A door 13 is provided on the machine body 1 for convenient access to the water tank, so as to regularly clean the water tank. The water tank is equipped with a drainage pipe. At the same time, since there is also a possibility of a small amount of liquid dripping in the soaking area and the drying area, a drainage structure is usually set in the machine body 1. It is important that the machine body 1 has an electronic device assembly chamber 14 separated from the cleaning device 2, the glass plate soaking device 3 and the glass plate drying device 5. The main electronic devices are assembled in an independent and separated electronic device assembly chamber to ensure stable and reliable operation of the equipment.

[0035] In this specific embodiment, the soaking bin lifting drive mechanism 33 and the receiving bin lifting drive mechanism 52 both include a lifting drive motor, a lead screw positioned and rotatably matched on the machine body 1, and a nut slider matched with the lead screw. The nut slider is fixed on the glass plate placing bin 31 and the glass plate receiving bin 51. Of course, other lifting drive structures can also be used, such as a cylinder, a gear rack mechanism, etc., but the use of a lead screw nut structure in combination with a motor has the advantages of stable and reliable driving and easy automatic control.

Claims

1. An automatic glass plate cleaning machine for immunoblotting test, comprising a body, a cleaning device is arranged on the body, the cleaning device comprises a conveyor belt and a cleaning mechanism arranged along the conveyor belt, a glass plate positioning tool for positioning the glass plate is arranged on the conveyor belt, and the characteristics are: The machine body is also provided with a glass plate immersion device, the glass plate immersion device includes a glass plate placement bin with multiple glass plate shelves and a immersion chamber for immersing the glass plates in the glass plate placement bin, the glass plate placement bin is matched with a feeding mechanism on a glass plate positioning tooling for transferring the glass plates on the glass plate shelves to the conveyor belt; the glass plate placement bin is lifted and matched in the machine body, the feeding mechanism includes a immersion bin lifting drive mechanism for driving the glass plate placement bin to lift, and the machine body is provided with a discharge station, a immersion station and a feeding station in sequence along the lifting direction of the glass plate placement bin. The glass plate placement bin is located at the front end of the conveyor belt cleaning process, and the glass plate shelves are inclined downwardly towards one end of the conveyor belt in a slope shape. The low end of the glass plate shelves is a slide-out end for sliding out the glass plates, and the high end of the glass plate shelves is an insertion end for inserting the glass plates onto the glass plate shelves. The glass plate placement bin includes a frame-shaped main body, the frame-shaped main body has a bottom and closed side panels located on both sides of the glass plate shelves, and the frame-shaped The main body is equipped with a sealing gate at the sliding-out end of the glass plate shelf rack corresponding to the glass plate shelf rack, and the sealing gate is sealed and inserted on the frame-shaped main body along the lifting direction of the glass plate placement bin, and a blocking part is provided in the machine body to block the sealing gate from following the glass plate placement bin to descend to the feeding station. The sealing gate is blocked by the blocking part during the process of the glass plate placement bin descending from the immersion station to the feeding station, so that the glass plate placement bin exposes the sliding-out end of the glass rod shelf rack. The glass plate shelf rack corresponds to the glass plate sliding into the glass plate positioning fixture of the conveyor belt along the sliding-out end of the glass plate shelf rack during the feeding process, and as the conveyor belt moves to complete the glass plate sliding into and positioning on the glass plate positioning fixture, the sealing gate rises with the glass plate placement bin to the discharging station, and a sealing bin door corresponding to the immersion station is provided in the machine body for closing a side opening corresponding to the input end of the glass plate placement bin located at the immersion station, and the inner cavity of the glass plate placement bin located at the immersion station is surrounded by the sealing bin door and the sealing gate to form the immersion chamber, and the immersion chamber is provided with a liquid injection port and a liquid discharge port.

2. The automatic glass plate cleaning machine for immunoblotting test according to claim 1, characterized in that: The glass plate placement bin has a reset process for automatically resetting to the soaking station after the glass plate shelves have passed the feeding station. The machine body is provided with a holding part for holding the sealing gate at the soaking station when the glass plate placement bin is reset.

3. The automatic glass plate cleaning machine for immunoblotting test according to claim 1, characterized in that: The sealed compartment door is slidably matched on the machine body along the direction of the placement end facing the glass plate placement compartment, and the sealed compartment door is matched with a compartment door driver for driving the sealed compartment door to slide.

4. The automatic glass plate cleaning machine for immunoblotting test according to claim 1, characterized in that: The glass plate positioning tooling includes a positioning and resting groove cavity with positioning walls on all sides, and a rubber pressure needle assembly is arranged at the four corner positions of the positioning and resting groove cavity, the rubber pressure needle assembly includes a flexible rubber pressure needle and a needle seat for fixing the rubber pressure needle, the needle seat is slidably fitted on the conveyor belt along the width direction of the conveyor belt, and the rubber pressure needle can enter and exit the positioning and resting groove cavity as the needle seat slides, the rubber pressure needle is spaced from the bottom of the positioning and resting groove cavity for the glass plate to be inserted, the needle seat is equipped with a driving spring for driving the needle seat to move the rubber pressure needle into the positioning and resting groove cavity, the needle seat has a toggle end located on the side of the conveyor belt, and a toggle piece is arranged on the side of the end of the conveyor belt corresponding to the glass plate receiving the glass plate on the body, as the conveyor belt moves, the toggle end of the needle seat passes through the toggle piece and is toggled by the toggle piece to make the rubber pressure needle exit the positioning and resting groove cavity, the toggle piece corresponds to the position where the rubber pressure needle assembly located at the rear enters the glass plate, so as to facilitate the glass plate to fall into the positioning and resting groove cavity.

5. The automatic glass plate cleaning machine for immunoblotting test according to claim 1, characterized in that: The conveyor belt is formed into a ring by splicing a number of chain plates, and the middle part of the chain plate between adjacent positioning and shelving grooves is hollow. The cleaning mechanism includes an initial wiping roller bar, a flushing nozzle, a secondary wiping roller bar, a cleaning nozzle and a water removal roller bar arranged in sequence along the movement direction of the conveyor belt. The flushing nozzle and the cleaning nozzle are both facing the direction of the conveyor belt cleaning starting position. The flushing nozzle and the cleaning nozzle are equipped with a cleaning liquid storage tank, and a water receiving tray is provided in the middle of the conveyor belt.

6. The automatic glass plate cleaning machine for immunoblotting test according to claim 5, characterized in that: A first roller mounting arm and a second roller mounting arm are rotatably arranged on the machine body, an initial wiping roller is detachably mounted on one end of the first roller mounting arm, a spare initial wiping roller is detachably mounted on the other end of the first roller mounting arm, a secondary wiping roller is detachably mounted on one end of the second roller mounting arm, a spare secondary wiping roller is detachably mounted on the other end of the second roller mounting arm, the first roller mounting arm and the second roller mounting arm are connected with a rotation driving mechanism for driving the first roller mounting arm and the second roller mounting arm to rotate, and a disassembly and assembly operation window for exposing the spare initial wiping roller and the spare secondary wiping roller is opened on the machine body.

7. The automatic glass plate cleaning machine for immunoblotting test according to claim 1, characterized in that: The conveyor belt is connected to a glass plate drying device at the end of the cleaning process. The glass plate drying device includes a glass plate receiving bin for receiving the glass plates cleaned on the conveyor belt, and a drying chamber for drying the glass plates in the glass plate receiving bin is provided on the machine body.

8. The automatic glass plate cleaning machine for immunoblotting test according to claim 7, characterized in that: The glass plate receiving bin is lifted and matched on the machine body, and the glass plate receiving bin is matched with a receiving bin lifting driving mechanism for driving the glass plate receiving bin to lift and lower, and the glass plate receiving bin is located at the end position of the cleaning process of the conveyor belt, and the glass plate receiving bin comprises a frame-shaped receiving bin main body, and a plurality of receiving racks for placing glass plates are longitudinally distributed in the receiving bin main body, and the receiving racks are arranged obliquely upward in the direction toward the conveyor belt, and the receiving bin main body has a glass plate sliding entrance facing the conveyor belt, a closed back plate and a bottom plate opposite to the glass plate sliding entrance, and a sealed bottom cover plate is magnetically attracted on the bottom plate of the receiving bin main body, and the machine body is provided with a drying station above the conveyor belt, A U-shaped box plate is provided at the drying station, and a hot air outlet is provided on the U-shaped box plate. A hot air generating device for supplying hot air through the hot air outlet is provided on the machine body. When the glass plate receiving bin enters the drying process, it is inserted into the U-shaped box plate and is laterally closed by the U-shaped box plate, so that the glass plate receiving bin is surrounded by the U-shaped box plate and the closed back plate to form a cylindrical drying chamber during the drying process. The sealed bottom cover plate contacts and covers the bottom of the U-shaped box plate, thereby closing the bottom of the cylindrical drying chamber, and a magnetic attraction part that cooperates with the sealed bottom magnetic attraction is provided at the bottom of the U-shaped box plate. A bin cover that can open and close the top opening of the cylindrical drying chamber is provided on the machine body, and the glass plate receiving bin can rise and pass through the top opening of the U-shaped box plate.

9. The automatic glass plate cleaning machine for immunoblotting test according to claim 7, characterized in that: The machine body is provided with an electronic device assembly chamber which is separated from the area where the cleaning device, the glass plate soaking device and the glass plate drying device are located.

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