An artificial cornea storage box

The cornea preservation box addresses complex rehydration and visualization issues by providing a sealed storage compartment and integrated trephination platform, ensuring secure and efficient cornea handling for medical procedures.

CN111959944BActive Publication Date: 2025-07-15SHAANXI BOYU REGENERATIVE MEDICINE CO LTD
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Patent Information

Application Number
CN202010744792.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-07-29
Publication Date
2025-07-15
Estimated Expiration
2040-07-29

AI Technical Summary

Technical Problem

The existing artificial corneal preservation devices require complex rehydration before surgery, and there is a risk of corneal contamination and damage. The corneal is not easily identified in the preservation fluid, which brings inconvenience to clinical operation and lacks convenient corneal drilling devices.

Method used

An artificial corneal preservation box is designed, which contains a corneal preservation chamber and a storage cover, and is equipped with a storage cavity and a storage fluid storage cavity. It adopts a double-layer sealing structure, equipped with a gasket and an inner cover as a drilling table, and the cleaning dish is used for rehydration and cleaning of the cornea to ensure corneal fixation and protection.

Benefits of technology

It realizes stable preservation of the cornea, prevents slipping and contamination, improves the convenience of clinical operation, and simplifies the corneal drilling and cleaning process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention provides an artificial cornea storage box, which comprises a storage box and a cornea storage chamber. The cornea storage chamber includes a storage cavity and a storage cover. The storage cavity includes a side wall and a receiving cavity. The side wall includes an upper edge and a lower edge. The receiving cavity is a sunken cavity, and the edge of the sunken cavity is connected to the upper edge or the lower edge of the side wall or a part between the upper edge and the lower edge to form an integral body. The storage cover has a cover body that matches the receiving cavity, and the cover body is used to close the receiving cavity. The cornea storage chamber can well fix and protect the cornea, prevent the cornea from slipping into the preservation liquid cavity, and improve the convenience of doctors' clinical operations. The combination of the gasket and the inner cover or the storage cavity can form a cornea drilling platform to replace the disposable drilling platform currently used in clinical practice for cornea drilling. The cleaning dish can facilitate doctors to perform rehydration and cleaning work on the cornea.
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Description

Technical Field

[0001] The present invention belongs to the technical field of corneal preservation, and particularly relates to an artificial cornea storage box. Background Art

[0002] From the completion of production to implantation into a patient's body, an artificial cornea needs to go through processes such as packaging, transportation, and storage. Whether the cornea can be properly packaged during this process directly affects the quality of the cornea. Existing artificial cornea storage devices are mainly divided into two types. One is dry storage, where the artificial cornea is placed in a receiving cavity and desiccants are placed around it. Before the operation, the artificial cornea needs to be rehydrated, which makes the surgical process complex and increases the risk of contamination and damage to the artificial cornea. The other is storage with a storage solution, which has a simple surgical process and is more conducive to protecting the cornea.

[0003] The utility model patent with the application number 201820151069.8 provides an artificial cornea storage box. The base is provided with a boss for specifically storing the cornea, which cooperates with the lid to form a cornea storage cavity, and can well fix the cornea. A sealed cornea storage solution cavity is formed around the cornea storage cavity, and the cornea can be completely stored in the storage solution. This artificial cornea storage box has a simple structure and is provided with a double-layer sealing structure, which can well isolate the external environment and prevent the cornea and the storage solution from being contaminated. However, after the lid of the box is opened, the cornea is likely to slide from the boss into the storage solution cavity. Moreover, during the clinical use by doctors, especially during the corneal cleaning process, since the cornea is transparent and colorless, it is not easy to see the cornea in both the storage solution and the cleaning solution, which brings certain inconvenience to the actual clinical operation. In addition, currently, when the cornea is drilled before the operation, a special disposable drilling table is required. Currently, a storage device that is convenient for clinical use and can perform corneal drilling is needed. Summary of the Invention

[0004] In view of the problems existing in the prior art, the present invention provides an artificial cornea storage box.

[0005] To achieve the above-mentioned invention purpose, the present invention is implemented by adopting the following technical solutions:

[0006] A cornea storage chamber includes a storage cavity and a storage lid. The storage cavity includes a side wall and a receiving cavity. The side wall includes an upper edge and a lower edge. The receiving cavity is a concave cavity, and the edge of the concave cavity is connected to a part between the upper edge and the lower edge of the side wall or the upper edge or the lower edge of the side wall to form an integral body. The storage lid has a lid body that matches the shape of the receiving cavity, and the lid body is used to close the receiving cavity.

[0007] Preferably, the orthographic projection shape of the side wall is circular.

[0008] Preferably, a first external thread is provided on the outer side of the side wall.

[0009] Preferably, the shape of the sunken cavity is spherical.

[0010] Preferably, a part of the spherical surface is made into a plane.

[0011] Preferably, the orthographic projection shape of the side wall is rectangular, and convex ribs are provided on the outer side of the side wall.

[0012] Preferably, the shape of the sunken cavity is an inverted trapezoidal platform.

[0013] Preferably, a chamfer is provided at the connection in the vertical direction of the side wall.

[0014] Preferably, a chamfer is provided at the connection of the inverted trapezoidal platform.

[0015] Preferably, at least one first liquid passage hole is provided in the sunken cavity, for example: 2, 3, 4, 5, 6, 7.

[0016] Preferably, the shape of the first liquid passage hole is circular, oval, square, rectangular or rhombic.

[0017] Preferably, a support is provided at the lower end of the side wall, and the orthographic projection shape of the support is an annular shape or a rectangular ring, and the orthographic projection shape of the support is larger than the orthographic projection shape of the side wall.

[0018] Preferably, at least two first support feet are provided at the lower end of the support, and the shape of the first support feet is a cube, a tile shape or a trapezoidal platform.

[0019] Preferably, the storage cover further includes a sealing frame, and the orthographic projection shape of the sealing frame is an annular shape or a rectangular ring, and the edge of the cover body is connected to the inner side of the annular or rectangular ring of the sealing frame.

[0020] Preferably, at least two second support feet are provided at the lower part of the sealing frame, the shape of the second support feet is a cube, a tile shape or a trapezoidal platform, and a first internal thread is provided on the inner side of the second support feet for connecting with the first external thread on the side wall. Preferably, convex ribs are provided on the inner side of the support feet for engaging with the convex ribs on the side wall.

[0021] Preferably, the shape of the cover body is circular or rectangular.

[0022] Preferably, the shape of the cover body is spherical or an inverted trapezoidal platform.

[0023] Preferably, at least one second liquid passage hole is provided in the cover body, for example: 2, 3, 4, 5, 6, 7. The shape of the second liquid passage hole is circular, oval, square, rectangular or rhombic.

[0024] Preferably, at least two bumps are provided on the upper part of the sealing frame.

[0025] An artificial cornea storage box includes a storage box and a cornea storage chamber, and the cornea storage chamber is stored inside the artificial cornea storage box.

[0026] The structure of the storage box includes: a base, an inner cover, and a cleaning dish. The base includes a bottom plate, a first sealing platform, and a second sealing platform. The bottom plate is a cube with a circular or rectangular orthographic projection shape; the first sealing platform is provided on the upper surface of the bottom plate, and the first sealing platform is a cube with a circular or rectangular orthographic projection shape; the orthographic projection shape of the first sealing platform is smaller than that of the bottom plate; the second sealing platform is provided on the upper surface of the first sealing platform, and the second sealing platform is in a cylindrical or rectangular cylindrical shape. The hollow position surrounded by the second sealing platform forms a storage liquid storage cavity.

[0027] Preferably, at least one raised sealing ring is provided on the top surface of the storage liquid storage cavity, and a gasket is provided on the inner side of the top surface of the inner cover. The gasket is circular and is provided on the inner layer of the inner cover. The first bump and the second external thread cooperate so that the gasket and the raised sealing ring are closely fitted to form a double-layer sealing structure to seal the storage liquid storage cavity, which can effectively prevent the cornea and the cornea storage liquid from being contaminated.

[0028] Preferably, the shape of the inner cover matches that of the second sealing platform, and the inner cover is used to seal the storage liquid storage cavity; the shape of the cleaning dish matches that of the first sealing platform, and the cleaning dish is used to seal the first sealing platform.

[0029] Preferably, a third external thread is provided on the outer side of the first sealing platform.

[0030] Preferably, a second external thread is provided on the outer side of the second sealing platform.

[0031] Preferably, a first convex rib is provided on the inner wall of the inner cover for sealing connection with the second external thread on the outer side of the second sealing platform. Preferably, the inner cover and the second sealing platform are connected by a buckle.

[0032] Preferably, a second convex rib is provided on the inner wall of the cleaning dish for sealing connection with the third external thread on the outer side of the first sealing platform. Preferably, the cleaning dish and the first sealing platform are connected by a buckle.

[0033] Preferably, the combination of the gasket and the inner cover can be used as a drilling platform for the cornea, and the storage cavity can also be used as a drilling platform for the cornea to replace the disposable special corneal drilling platform currently used in clinics.

[0034] Preferably, the cleaning dish is provided with a volume scale, and the cleaning dish can facilitate the doctor to perform the rehydration and cleaning work of the cornea.

[0035] Preferably, the upper surface of the inner cover is provided with a groove, and a refrigerant is placed in the groove for cooling the preservation liquid storage cavity.

[0036] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0037] The present invention provides an artificial cornea storage box, which is provided with a cornea storage chamber. The cornea storage chamber includes a storage cavity and a storage cover. The storage cavity and the storage cover are detachably connected to form a preservation liquid storage cavity. The cornea preservation liquid and the cornea storage chamber are stored in the preservation liquid storage cavity. The cornea storage chamber can well fix and protect the cornea, prevent the cornea from slipping into the preservation liquid cavity, and improve the convenience of doctors' clinical operations. In addition, the combination of the gasket and the inner cover or the storage cavity can be used as a cornea drilling platform to replace the disposable drill table currently used in clinical practice for cornea drilling. The cleaning dish can facilitate doctors to perform the rehydration and cleaning work of the cornea. Description of the Drawings

[0038] Figure 1 is a perspective view of the artificial cornea storage box of the present invention;

[0039] Figure 2 is a perspective view of the cornea storage chamber of the present invention;

[0040] Figure 3 is a sectional view of the cornea storage chamber of the present invention;

[0041] Figure 4 is a perspective view of the storage cover of the cornea storage chamber of the present invention;

[0042] Figure 5 is a top view of the storage cover of the cornea storage chamber of the present invention;

[0043] Figure 6 is a bottom view of the storage cover of the cornea storage chamber of the present invention;

[0044] Figure 7 is a sectional view of the storage cover of the cornea storage chamber of the present invention;

[0045] Figure 8 is a perspective view of the storage cavity of the cornea storage chamber of the present invention;

[0046] Figure 9 is a perspective view of the inner cover of the present invention;

[0047] Figure 10 is a perspective view of the cleaning dish of the present invention.

[0048] 1 - Base; 2 - Cornea storage chamber; 3 - Inner cover; 4 - Gasket; 5 - Cleaning dish; 6 - Storage cover; 7 - Storage cavity; 8 - Bump; 9 - Second leg; 10 - First liquid passage groove; 11 - Second liquid passage hole; 12 - Internal thread; 13 - First leg; 14 - Second liquid passage groove; 15 - First liquid passage hole; 16 - First external thread; 17 - Cornea storage cavity; 18 - Preservative solution storage cavity; 19 - Top surface; 20 - Raised sealing ring; 21 - Second external thread; 22 - Third external thread; 23 - Capacity scale; 24 - Second convex rib; 25 - First convex rib; 26 - Cover body; 27 - Accommodation cavity; 28 - Side wall; 29 - Bracket; 30 - Sealing bracket. Detailed implementation manners

[0049] The technical solution of the present invention will be further described below through specific implementation manners. Those skilled in the art should understand that the embodiments are only for helping to understand the present invention and should not be regarded as specific limitations on the present invention.

[0050] As Figure 1 shown, this embodiment discloses an artificial cornea storage box, including a storage box and a cornea storage chamber 2, and the cornea storage chamber 2 is stored inside the artificial cornea storage box. The structure of the storage box includes: a base 1, an inner cover 3 and a cleaning dish 5. The base 1 includes a bottom plate, a first sealing platform and a second sealing platform. The bottom plate is a cube with a circular or rectangular orthographic projection shape; the first sealing platform is arranged on the upper surface of the bottom plate, and the first sealing platform is a cube with a circular or rectangular orthographic projection shape; the orthographic projection shape of the first sealing platform is smaller than that of the bottom plate; the second sealing platform is arranged on the upper surface of the first sealing platform, and the second sealing platform is in a cylindrical or rectangular cylindrical shape, and the hollow position surrounded by the second sealing platform constitutes a preservative solution storage cavity 18.

[0051] At least one raised sealing ring 20 is arranged on the top surface 19 of the preservative solution storage cavity 18, and a gasket 4 is arranged inside the top surface of the inner cover 3. The gasket 4 is circular and is arranged inside the inner cover 3. The first convex block 25 and the second external thread 21 cooperate to make the gasket 4 and the raised sealing ring 20 fit tightly, forming a double-layer sealing structure to seal the preservative solution storage cavity 18, which can effectively prevent the cornea and the cornea preservative solution from being contaminated. The combination of the gasket 4 and the inner cover 3 can be used as a drilling platform for the cornea, and the storage cavity 7 can also be used as a drilling platform for the cornea to replace the disposable cornea special drilling platform currently used in clinical practice.

[0052] As Figure 2As shown in the figure, this embodiment discloses a corneal preservation chamber. The corneal preservation chamber 2 includes a preservation cavity 7 and a preservation cover 6. The preservation cavity 7 includes a side wall 28 and a receiving cavity 27. The orthographic projection shape of the side wall 28 is circular. The side wall 28 includes an upper edge and a lower edge. The receiving cavity 26 is a sunken cavity, and the shape of the sunken cavity is spherical. The edge of the cavity is connected to the upper edge or the lower edge of the side wall 28 or a part between the upper edge and the lower edge to form an integral body. The preservation cover 6 has a cover body 26 that matches the shape of the receiving cavity 27, and the cover body 26 is used to close the receiving cavity 27.

[0053] As Figure 3 shown in the figure, the preservation liquid storage cavity 17 is formed by the receiving cavity 27, the cover body 26 and four second support feet 9. The shape of the receiving cavity 27 is spherical, the shape of the cover body 26 is circular, the diameter of the circle formed by the edge of the receiving cavity 27 and the cover body 26 is not less than 8 mm, and the distance between the receiving cavity 27 and the cover body 26 is not less than 0.5 mm, so as to avoid problems such as the cornea flipping, folding, and deforming in the preservation cavity.

[0054] As Figure 4 shown in the figure, the preservation cover 6 further includes a sealing frame 30. The orthographic projection shape of the sealing frame 30 is a circular ring or a rectangular ring. The edge of the cover body 26 is connected to the inner side of the circular ring or the rectangular ring of the sealing frame 30. At least two second support feet 9 are provided at the lower part of the sealing frame 30. The shape of the second support feet 9 is a cube, a tile shape, or a trapezoidal platform. Internal threads are provided on the inner side of the second support feet 9. Six convex blocks 8 are provided at the upper part of the sealing frame 30. First liquid passage grooves 10 are formed between every two of the convex blocks or the second support feet, and second liquid passage grooves 14 are formed between every two of the second support feet.

[0055] As Figure 5 and 6 shown in the figure, a first liquid passage hole 15 is provided in the sunken cavity, and a second liquid passage hole 11 is provided in the cover body 26. The diameters of the first liquid passage hole 15 or the second liquid passage hole 11 may not be completely consistent. The shape of the second liquid passage hole 11 is circular, oval, square, rectangular, or rhombic. The first liquid passage grooves 10, the second liquid passage grooves 14, the first liquid passage hole 15, and the second liquid passage hole 11 can ensure that the preservation liquid enters the corneal preservation cavity 17 to meet the wet preservation of the cornea.

[0056] As Figure 7 and 8As shown, a support 29 is provided at the lower end of the side wall 28. The orthographic projection shape of the support 29 is an annular shape or a rectangular ring, and the orthographic projection shape of the support 29 is larger than that of the side wall 28. At least two first support feet 13 are provided at the lower end of the support 29, and the shape of the support feet 13 is a cube, a tile shape or a frustum of a pyramid. The surface of the sunken cavity is provided with a first liquid through hole 15, and the shape of the first liquid through hole 15 is a circle, an ellipse, a square, a rectangle or a rhombus.

[0057] As Figure 1 and 9 shown, the shape of the inner cover 3 matches that of the second sealing platform, and the inner cover 3 is used to seal the preservation liquid storage cavity 18. A second external thread 21 is provided on the outside of the second sealing platform, and a first convex rib 25 is provided on the inner wall of the inner cover 3 for sealing connection with the second external thread 21 on the outside of the second sealing platform. Another connection method between the inner cover 3 and the preservation liquid storage cavity 18 is by snap connection.

[0058] As Figure 1 and 10 shown, the shape of the cleaning dish 5 matches that of the first sealing platform, and the cleaning dish 5 is used to seal the first sealing platform. A third external thread 22 is provided on the outside of the first sealing platform, and a second convex rib 24 is provided on the inner wall of the cleaning dish 5 for sealing connection with the third external thread 22 on the outside of the first sealing platform. Another connection method between the cleaning dish 5 and the base 1 is by snap connection. The cleaning dish 5 is provided with a capacity scale 23, and the cleaning dish 5 can facilitate the doctor to perform the rehydration and cleaning work of the cornea.

[0059] Specific working process:

[0060] During actual use, place the artificial cornea on the accommodation cavity 27 of the storage cavity 7, and then screw the storage cover 6 onto the first external thread 16 through the internal thread 12 to assemble the cornea storage chamber 2, with the artificial cornea stored in the cornea storage cavity 17. Then, add an appropriate amount of cornea preservation solution into the preservation solution storage cavity 18 provided on the base 1, and place the cornea storage chamber 2 containing the artificial cornea into the preservation solution storage cavity 18. In the present invention, the first liquid passage groove 10, the second liquid passage groove 14, the second liquid passage hole 11, and the first liquid passage hole 15 provided on the storage cavity 7 and the storage cover 6 can ensure that the preservation solution enters the preservation solution storage cavity 18 and flows freely, meeting the requirements for wet preservation of the cornea. Place the gasket 4 flatly into the inner cover 3, and then screw the assembled inner cover 3 onto the first convex rib 25 and the second external thread 21. The gasket 4 and the raised sealing ring 20 form a double-layer sealing structure to form a sealed preservation solution storage cavity 18. The cleaning dish 5 is fixedly connected and tightened through the second convex rib 24 and the third external thread 22. Operations such as rehydration and cleaning of the artificial cornea can be achieved in the cleaning dish 5, and the drilling of the artificial cornea can be carried out on the combination of the gasket 4 and the inner cover 3, or on the drilling platform of the storage cavity 7.

[0061] In summary, the artificial cornea storage box is provided with a cornea storage chamber, which can well fix and protect the cornea. Moreover, the combination of the gasket and the inner cover, or the storage cavity can be used as a drilling platform for the cornea, replacing the disposable drilling platform currently used in clinical practice for cornea drilling. The cleaning dish can facilitate doctors to carry out rehydration and cleaning of the cornea.

[0062] The above is only the specific implementation manner of this application, but the protection scope of this application is not limited thereto. Any changes or substitutions within the technical scope disclosed in this application should be covered within the protection scope of this application. Therefore, the protection scope of this application should be subject to the protection scope of the claimed rights.

Claims

1. An artificial cornea storage box, characterized in that, It includes a storage box and a corneal storage chamber (2), and the corneal storage chamber (2) is stored inside the artificial corneal storage box; The corneal storage chamber (2) includes a storage cavity (7) and a storage cover (6). The storage cavity (7) includes a side wall (28) and a receiving cavity (27). The side wall (28) includes an upper edge and a lower edge. The receiving cavity (27) is a concave cavity, and the edge of the concave cavity is connected to the upper edge or the lower edge of the side wall (28) or a part between the upper edge and the lower edge to form an integral body; The storage cover (6) has a cover body (26) matching the receiving cavity (27), and the cover body (26) is used to close the receiving cavity (27); The diameter of the circle formed by the edge of the receiving cavity (27) and the cover body (26) is not less than 8 mm, and the distance between the receiving cavity (27) and the cover body (26) is not less than 0.5 mm; The structure of the storage box includes: a base (1), an inner cover (3) and a cleaning dish (5). The base (1) includes a bottom plate, a first sealing platform and a second sealing platform. The bottom plate is a cube with a circular or rectangular orthographic projection shape; The first sealing platform is arranged on the upper surface of the bottom plate, and the first sealing platform is a cube with a circular or rectangular orthographic projection shape; The orthographic projection shape of the first sealing platform is smaller than that of the bottom plate; The second sealing platform is arranged on the upper surface of the first sealing platform, and the second sealing platform is in a cylindrical shape or a rectangular cylindrical shape. The hollow position surrounded by the second sealing platform constitutes a preservation liquid storage chamber (18); The storage cavity (7) and the storage cover (6) are detachably connected. The corneal preservation liquid and the corneal storage chamber (2) are stored in the preservation liquid storage chamber (18); The shape of the inner cover (3) matches that of the second sealing platform, and the inner cover (3) is used to seal the preservation liquid storage chamber (18); The shape of the cleaning dish (5) matches that of the first sealing platform, and the cleaning dish (5) is used to seal the first sealing platform; A gasket (4) is arranged on the inner side of the top surface of the inner cover (3).

2. The artificial cornea storage box according to claim 1, characterized in that The shape of the concave cavity is a spherical surface or an inverted trapezoidal platform, and at least one first liquid passing hole (15) is arranged on the surface. The shape of the first liquid passing hole (15) is circular, elliptical, rectangular or rhombic; At least one second liquid passing hole (11) is arranged on the cover body (26), and the shape of the second liquid passing hole (11) is circular, elliptical, rectangular or rhombic.

3. The artificial cornea storage box according to claim 1, characterized in that, A support (29) is arranged at the lower end of the side wall (28). The orthographic projection shape of the support (29) is a circular ring or a rectangular ring, and the orthographic projection shape of the support (29) is larger than that of the side wall (28); At least two first support feet (13) are arranged at the lower end of the support (29), and the shape of the first support feet (13) is a cube, a tile shape or a trapezoidal platform.

4. The artificial cornea storage box according to claim 1, characterized in that, The storage cover (6) further includes a sealing frame (30), the orthographic projection shape of the sealing frame (30) is a circular ring or a rectangular ring, and the edge of the cover body (26) is connected to the inner side of the sealing frame (30); at least two second supporting feet (9) are arranged at the lower part of the sealing frame (30), and the shape of the second supporting feet (9) is a cube, a tile shape or a frustum of a pyramid.

5. The artificial cornea storage box according to claim 4, characterized in that, An external first thread (16) or a convex rib is arranged on the outer side of the side wall (28), and an internal thread (12) or a convex rib is arranged on the inner side of the second supporting feet (9). The side wall (28) is connected to the second supporting feet (9) through the external first thread (16) and the internal thread (12) or through two convex ribs.

6. The artificial cornea storage box according to claim 1, wherein, An external second thread (21) is arranged on the outer side of the second sealing platform, and a first convex rib (25) is arranged on the inner wall of the inner cover (3). The first convex rib (25) is used for sealing connection with the external second thread (21) on the outer side of the second sealing platform.

7. The artificial cornea storage box according to claim 1, characterized in that, An external third thread (22) is arranged on the outer side of the first sealing platform, and a second convex rib (24) is arranged on the inner wall of the cleaning dish (5). The second convex rib (24) is used for sealing connection with the external third thread (22) on the outer side of the first sealing platform.

Citation Information

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