Particle beam therapy device

Abstract

The present disclosure relates to the technical field of tumor radiotherapy, and specifically provides a particle beam therapy device. The particle beam therapy device comprises a fixed support device, a synchrotron, a rotating support device, a first deflection magnet group, a second deflection magnet group and an irradiation head, wherein the fixed support device comprises a base and a driving and rotating mechanism; the rotating support device supports the synchrotron, the synchrotron is connected to a first conveying channel, and the driving and rotating mechanism drives the rotating support device to rotate; the first deflection magnet group is arranged on the rotating support device, the output end of the first deflection magnet group extends toward a side of the rotating support device away from the first conveying channel, and the output end or the extension line of the output end thereof crosses the rotating support device; the particle beam outputted by the first deflection magnet group enters the second deflection magnet group, and the output end of the second deflection magnet group points to the rotation center line of the rotating support device; the irradiation head is connected to the end of the second deflection magnet group.

Description

Technical Field

[0001] The present disclosure relates to the technical field of tumor radiotherapy, and in particular to a particle beam therapy device. Background Art

[0002] Particle accelerators can be used in tumor radiotherapy, such as accelerating particle beams in heavy ion therapy or proton therapy. The accelerated particle beam needs to be guided to the patient's target tissue, and it is often necessary to irradiate the target tissue from different directions to enhance the treatment effect or reduce the radiation to surrounding healthy tissue.

[0003] In some tumor radiotherapy systems, the particle beam generator and accelerator are fixed to the ground, and the treatment room is set near the accelerator. Therefore, the particle beam emitted by the accelerator needs to be diverted and guided into the treatment room. Specifically, a complex system consisting of deflection magnets and focusing magnets is required to guide the particle beam from the particle accelerator to the target. The system is large in size and expensive to manufacture. In addition, the distance between the treatment room and the accelerator is large, and the particle beam will lose energy during transmission, which may reduce the control accuracy of the irradiation dose. Summary of the invention

[0004] In order to solve the above technical problems or at least partially solve the above technical problems, the present disclosure provides a particle beam therapy device.

[0005] The present disclosure provides a particle beam therapy device for emitting a particle beam to a target tissue, comprising:

[0006] A fixed support device, comprising a base, on which a driving rotation mechanism is provided, used as a support base;

[0007] A synchrotron accelerator is used to accelerate a particle beam, wherein the synchrotron accelerator has a deflection magnet and is connected to a first conveying channel, wherein the first conveying channel conveys the particle beam obliquely upward;

[0008] A rotating support device, used to support the synchrotron, the rotating support device being rotatably arranged on the fixed support device; the rotating support device has a rotating center line when rotating, and the power provided by the driving rotation mechanism can cause the rotating support device to rotate around the rotating center line;

[0009] a first deflection magnet group, arranged on the rotating support device, and used for receiving and conveying the particle beam outputted from the first conveying channel, wherein the particle beam outputted from the first conveying channel enters into the first deflection magnet group along the tangent direction of the input end of the first deflection magnet group, the first deflection magnet group is arc-shaped, the output end of the first deflection magnet group extends toward a side of the rotating support device away from the first conveying channel, and the output end of the first deflection magnet group or an extension line of the output end of the first deflection magnet group crosses the rotating support device;

[0010] a second deflection magnet group, connected to the first deflection magnet group, and used for receiving and transmitting the particle beam output by the first deflection magnet group, the second deflection magnet group is arc-shaped, the particle beam output by the first deflection magnet group enters the second deflection magnet group along the tangent direction of the input end of the second deflection magnet group, and the output end of the second deflection magnet group points to the rotation center line of the rotation support device;

[0011] The irradiation head is connected to the end of the second deflection magnet group, and the particle beam is emitted from the irradiation head to the target tissue.

[0012] Optionally, the first deflection magnet group and the second deflection magnet group have the same number of deflection magnet bodies or at least partial structures and parameters as the deflection magnet groups in the synchrotron.

[0013] Optionally, the first deflection magnet group and the second deflection magnet group have the same structure and parameters as the deflection magnet group in the synchrotron and the same number of deflection magnet bodies.

[0014] Optionally, the output end of the first deflection magnet group is connected to a first deflection magnet, and the particle ejection velocity deflected by the first deflection magnet enters the second deflection magnet group along the tangent direction of the input end of the second deflection magnet group.

[0015] Optionally, a second conveying channel is provided between the first deflection magnet group and the second deflection magnet group, and the particles deflected by the first deflection magnet enter the second conveying channel along the combing conveying direction of the second conveying channel, and the output end of the second conveying channel is tangent to the connection point of the second deflection magnet group.

[0016] Optionally, a first focusing magnet is provided on the periphery of the second conveying channel.

[0017] Optionally, the first deflection magnet deflects the particle beam output by the first deflection magnet group to a horizontal direction or parallel to a supporting surface of the base.

[0018] Optionally, a tangent direction of an output end of the first deflection magnet group is horizontal or parallel to a supporting surface of the base.

[0019] Optionally, the plane where the first deflection magnet group is located is coplanar with the plane where the second deflection magnet group is located.

[0020] Optionally, the particle beam output by the second deflection magnet group is perpendicular to the rotation center line of the rotation support device.

[0021] Optionally, the plane where the second deflection magnet group is located is perpendicular to a horizontal plane or a supporting surface of the base.

[0022] Optionally, the rotation centerline of the rotation support device is parallel to a horizontal plane or a support surface of the base.

[0023] Optionally, a plane where the first deflection magnet group is located forms an angle with a plane where the second deflection magnet group is located.

[0024] Optionally, an annular structure is provided on both sides of the rotating support device, the annular structure is coaxial with the rotating support device, the annular structure is rotatably arranged on the fixed support device, and the outer diameter of the annular structure is smaller than the radial distance of the farthest radial point of the rotating support device.

[0025] Optionally, the deflection magnet bodies in the first deflection magnet group, the deflection magnet bodies in the second deflection magnet group, and the deflection magnet bodies in the deflection magnet group in the synchrotron all have focusing edges.

[0026] Optionally, a vertical plane between the particle beam motion trajectory in the first transport channel and a plane where the particle beam motion trajectory in the synchrotron is located is perpendicular to a horizontal plane or a supporting surface of the base.

[0027] Optionally, the plane where the particle beam motion trajectory in the synchrotron is located is perpendicular to the supporting surface or horizontal plane of the base.

[0028] Compared with the prior art, the technical solution provided by the embodiments of the present disclosure has the following advantages:

[0029] Compared with the structure in which the synchrotron and the beam transport device are arranged separately, the synchrotron, the first deflection magnet group and the second deflection magnet group integrated on the rotating support device can significantly save space. And the particle beam output by the synchrotron enters the first deflection magnet group along the tangent direction of the input end of the first deflection magnet group, so there is no need to set the deflection magnet and the focusing magnet at the input end of the first deflection magnet group, so that the overall height of the particle beam therapy device is reduced, and the first deflection magnet group extends toward the side of the rotating support device away from the first transport channel and crosses the rotating support device, so that the overall axial length of the particle beam therapy device is reduced. The reduction in height and length can reduce the space occupied by the particle beam therapy device, thereby saving the overall construction cost and construction difficulty of the building that accommodates the particle beam therapy device, and realizing an ultra-miniaturized synchrotron particle beam therapy device. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present disclosure and, together with the description, serve to explain the principles of the present disclosure.

[0031] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, for ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0032] Figure 1 It is a schematic diagram of a particle beam therapy device when the output end of the first deflection magnet group is connected to the first deflection magnet according to an embodiment of the present disclosure;

[0033] Figure 2 for Figure 1 The main view of

[0034] Figure 3 for Figure 1 Left view of

[0035] Figure 4 for Figure 1 A top view of

[0036] Figure 5 for Figure 1 A schematic diagram of a particle beam therapy device after the rotation support device is hidden;

[0037] Figure 6 for Figure 1 A schematic diagram of a cylinder connected to the side of the central rotating support device;

[0038] Figure 7It is a schematic diagram of a particle beam therapy device when the tangent direction of the output end of the first deflection magnet group according to an embodiment of the present disclosure is horizontal or parallel to the supporting surface of the base;

[0039] Figure 8 for Figure 7 Left view of

[0040] Fig. 9 for Figure 7 A schematic diagram of a particle beam therapy device after the rotation support device is hidden;

[0041] Fig.10 for Figure 7 A schematic diagram of a cylinder connected to the side of the central rotating support device;

[0042] Fig.11 A schematic diagram of an annular support plate being arranged on both sides of the rotating support device according to an embodiment of the present disclosure;

[0043] Fig.12 for Fig.11 Left view of

[0044] Fig.13 A schematic diagram of a plane where the synchrotron accelerator is located and a plane where the second deflection magnet group is located according to an embodiment of the present disclosure;

[0045] Fig.14 is a schematic diagram of the plane where the first deflection magnet group is located in an embodiment of the present disclosure;

[0046] Fig.15 It is a schematic diagram of a vertical plane between the particle beam motion trajectory described in an embodiment of the present disclosure and the plane where the particle beam motion trajectory of the synchrotron is located.

[0047] Among them, 10, the plane where the synchrotron is located; 11, the plane where the first deflection magnet group is located; 12, the plane where the second deflection magnet group is located; 13, the vertical plane; 14, the rotation center line; 100, the fixed support device; 110, the first support; 120, the second support; 200, the rotating support device; 210, the annular plate; 220, the cylinder; 230, the support rod; 240, the annular support plate; 300, the injection device; 310, the driving device; 400, the synchrotron; 410, the first deflection magnet body; 500, the first deflection magnet group; 510, the second deflection magnet body; 600, the second deflection magnet group; 610, the third deflection magnet body; 700, the support device; 800, the irradiation head; 900, the second conveying channel; 901, the first focusing magnet; 902, the first deflection magnet; 910, the first conveying channel; 911, the second focusing magnet. DETAILED DESCRIPTION

[0048] In order to more clearly understand the above-mentioned objectives, features and advantages of the present disclosure, the scheme of the present disclosure will be further described below. It should be noted that the embodiments of the present disclosure and the features in the embodiments can be combined with each other without conflict.

[0049] In the following description, many specific details are set forth to facilitate a full understanding of the present disclosure, but the present disclosure may also be implemented in other ways different from those described herein; it is obvious that the embodiments in the specification are only part of the embodiments of the present disclosure, rather than all of the embodiments.

[0050] Combination Figures 1 to 5 As shown, the particle beam therapy device provided in the embodiment of the present application is used to emit a particle beam to a target tissue. The particle beam therapy device includes a fixed support device 100, a rotating support device 200, an injection device 300, a synchrotron 400, a first deflection magnet group 500, a second deflection magnet group 600, a support device 700, a driving device 310, an irradiation head 800 and a control device (not shown in the figure).

[0051] The fixed support device 100 is fixed on the ground as a mounting base. In some embodiments, the base of the fixed support device 100 is the ground. A driving rotation mechanism is provided on the base to serve as a support base. The injection device 300 includes a particle source, which is fixed on the rotating support device 200 and is used to generate a particle beam and inject the particle beam into the synchrotron 400 after preliminary acceleration. Specifically, it can be a proton beam, a carbon ion beam or a helium ion beam.

[0052] The synchrotron 400 is fixed on the rotating support device 200, and is used to receive and accelerate the particle beam generated by the injection device 300. The synchrotron 400 has a deflection magnet. Preferably, the synchrotron 400 is fixed on the rotating support device 200 in an upright state, that is, the plane 10 where the particle beam motion trajectory in the synchrotron 400 is located is perpendicular to the support surface or horizontal plane of the base, thereby reducing the internal space occupied by the rotating support device 200. In other embodiments, the synchrotron 400 can also be tilted in the rotating support device 200, that is, the plane where the synchrotron 400 is located is at a certain angle to the vertical plane. This design can reduce the height of the particle beam therapy device. In combination with Fig.13 and Fig.14 As shown, the plane 10 where the synchrotron is located, the plane 11 where the first deflection magnet group is located, and the plane 12 where the second deflection magnet group is located here and below all refer to the plane where the trajectory of the particle beam in each device is located or the plane where the channel center line of the particle beam is located.

[0053] Combination Figure 4 and Figure 5As shown, the particle beam passes through the first deflection magnet group 500 and the second deflection magnet group 600 to receive the accelerated particle beam in turn, and irradiates the target area through the irradiation head 800. The support device 700 is used to support the patient. The support device 700 is driven by a movable mechanical mechanism (not shown) to adjust its relative position with the irradiation head 800. The support device 700 is preferably a treatment bed, which can be moved by a mechanical arm or a roller movable seat provided at the bottom. The driving device 310 is used to drive the rotating support device 200 to rotate on the fixed support device 100. The synchrotron 400 is connected to a first conveying channel 910, and the first conveying channel 910 conveys the particle beam obliquely upward.

[0054] Combination Figure 5 and Fig. 9 As shown, the synchrotron 400 includes four groups of deflection magnet groups and an accelerator. The number of deflection magnet bodies in each group of deflection magnet groups is multiple, and each group of deflection magnet groups includes four first deflection magnet bodies 410 in the illustrated embodiment. The accelerator may be a radio frequency accelerator. The first deflection magnet body 410 is used to deflect the particle beam through its magnetic field so that the particle beam can rotate along a circular orbit. The synchrotron 400 accelerates the particle beam to rotate in a circular manner to increase the energy or maintain it in a circular orbit. Further optimized, the first deflection magnet body 410 may also be configured to have an edge focusing effect. Among them, the number of the first deflection magnet bodies 410 in each group of deflection magnet groups shown in the figure is multiple, and the structure and parameters of the first deflection magnet bodies 410 in each group of deflection magnet groups are different. The figure is only for illustration and does not represent the actual structure of the first deflection magnet body 410. In some optional embodiments, the number of the first deflection magnet body 410 in each group of deflection magnet groups may also be one, so that the beam is rotated by 90 degrees. In other embodiments, the shape of the synchrotron 400 may also be a rounded rectangle or the like, and each rounded corner is composed of a plurality of deflection magnets, and the deflection magnets at the rounded corners can deflect the beam.

[0055] The fixed support device 100 includes a base and a driving rotation mechanism. Figure 1 and Figure 2 As shown, as a preferred solution, the driving rotation mechanism can be a plurality of rollers and a driving device 310, the rollers are rotatably arranged on the base, the axes of the plurality of rollers are parallel, and the plurality of rollers are arranged on the base along a concave arc track, and the outer peripheral surface of the roller forms a concave arc track. The driving device 310 can drive at least one roller to rotate. As an embodiment, the driving device 310 can be a motor or a motor reducer, or a reduction motor or other mechanism that can provide the roller pivot rotation by electric power. The driving rotation mechanism can also be other mechanisms that can drive an object to rotate.

[0056] Combination Figure 1 , Figure 2 and then Figure 7 As shown, the rotating support device 200 is used to support the synchrotron 400, that is, the synchrotron 400 is installed on the rotating support device 200, and the synchrotron 400 is coaxially arranged with the rotating support device 200. The rotating support device 200 is rotatably arranged on the fixed support device 100, and the rotating support device 200 has a rotation center line 14 when rotating. The power provided by the driving rotation mechanism can make the rotating support device 200 rotate around the rotation center line 14. Preferably, the rotation center line 14 of the rotating support device 200 is arranged parallel to the horizontal plane or the supporting surface of the base (that is, the upper surface of the base) for easy installation and control. In some embodiments, the rotating support device 200 is an annular bracket, specifically including two annular plates 210, the two annular plates 210 are concentrically arranged, and the two annular plates 210 are spaced apart so that a space for installing the synchrotron 400 is formed between the two annular plates 210. The outer circumference of the rotating support device 200 is of equal diameter to the arc track formed by the outer edge of the roller in the fixed support device 100, and is rotatably arranged on the outer circumference of the roller. The outer circumference of the roller is in tangential contact with the outer circumference of the rotating support device 200. When the roller rotates, it can drive the rotating support device 200 to rotate.

[0057] It should be understood that the shape of the rotating support device 200 and the connection method thereof with the fixed support device 100 are not limited to the above-mentioned structures, and other structures that can realize the installation and fixing of the synchrotron 400 and can rotate on the fixed support device 100 should also fall within the scope of protection claimed in the present disclosure. For example, the outer shape of the rotating support device 200 can be square, polygonal, etc., and the internal structure can adopt a hollow truss structure formed by short metal round tubes and cylinders fixedly connected to each other, which can greatly reduce the weight of the rotating support device 200.

[0058] The rotatable connection between the rotating support device 200 and the fixed support device 100 may also be in other forms, such as a ring structure may be provided on both end surfaces of the rotating support device 200 (the ring structure may be an arc shape or an open ring that can rotate the synchrotron 400 at a set angle, and the center angle of the arc or ring ensures that the synchrotron 400 can rotate at a preset angle, for example, greater than or equal to 90°. Preferably, it is a ring structure, such as Fig.11 As shown), two fixed support devices 100 are arranged in a matching manner. The annular structure is coaxial with the rotation center of the rotating support device 200, and the annular structure is rotatably arranged on the fixed support device 100, and the outer diameter of the annular structure is smaller than the radial distance of the farthest radial position of the rotating support device 200. At this time, the radius of the annular structure of the fixed support device 100 can be smaller. The outer circumferences of the two annular structures cooperate with the rollers on the fixed support device 100, and the rotating support device 200 is driven to rotate by the meshing or friction between the rollers and the outer circumferences of the annular structures.

[0059] Fig.11 It is a schematic diagram of an annular support plate 240 being provided on both sides of the rotation support device 200 according to an embodiment of the present disclosure; Fig.12 for Fig.11 The left view of the Fig.11 and Fig.12 The first deflection magnet group 500 and related components connected to the first deflection magnet group 500 are hidden in the figure, and only the position relationship between the rotating support device 200 and the annular support plate 240 is shown.

[0060] Specifically, combined Fig.11 and Fig.12 As shown, a plurality of support rods 230 are provided on both sides of the rotating support device 200, and the annular structure is an annular support plate 240, which is arranged at the end of the support rod 230, and then the two annular support plates 240 are fixedly supported on both sides of the rotating support device 200 through the support rod 230. The outer circumference of the annular support plate 240 cooperates with the roller on the fixed support device 100, and the annular support plate 240 is driven to rotate by the rotation of the roller, that is, rollers are provided on both sides of the rotating support device 200, and the rollers are rotatably arranged on the base, and the axes of the plurality of rollers are parallel, and the plurality of rollers are arranged on the base along a concave arc track, and the outer circumference of the roller forms a concave arc track and is tangent to the outer edge of the annular support plate 240. The driving device 310 can drive at least one roller to rotate. By supporting the annular support plate 240 through the roller groups on both sides, it can be ensured that the rotating support device 200 is supported and rotated more stably. Preferably, the rotating support device 200 is provided with a mechanism that can ensure that the rotating support device 200 does not tilt when rotating. The mechanism can be arranged inside the roller frame, on the base, or on the top or both side walls of the building body that contains the particle beam therapy device. For example, a roller or ball mechanism is arranged inside the roller frame, and the roller or ball is against the surface of the rotating support device 200. Preferably, the support rod 230 is perpendicular to the plane where the rotating support device 200 is located, and the center line of the annular support plate 240 coincides with the rotation center line 14 of the rotating support device 200, so that the rotating support device 200 is driven to rotate along its center line by the rotation of the annular support plate 240. Further optimized, the diameter of the annular support plate 240 is reduced as much as possible to ensure that the particle beam therapy device does not interfere when rotating. For example, first ensure that the part of the rotating support device with the largest radial distance does not interfere with the base during the rotation of the set angle. This design method can further reduce the overall height of the particle beam therapy device.

[0061] In other embodiments, the method of driving the rotating support device to rotate can be through gear transmission, a driving device is provided on the base, and a first gear is connected to the driving device, and the driving device can drive the first gear to rotate. Accordingly, a second gear meshing with the first gear is provided on the outer periphery of the annular plate 210 or the annular support plate 240, and then the annular plate 210 or the annular support plate 240 is driven to rotate by the rotation of the first gear. It can be seen that the specific matching method of the fixed support device 100 and the rotating support device 200 is not limited, and it is only necessary to satisfy that the fixed support device 100 drives the rotating support device 200 to rotate around its rotation center line 14.

[0062] Combination Figure 1 , Figure 3 , Figure 5 and Figure 8 As shown, the first deflection magnet group 500 is arranged on the rotating support device 200, and is used for receiving and conveying the particle beam output by the first conveying channel 910, that is, for receiving and conveying the particle beam output by the first conveying channel 910. The particle beam output by the first conveying channel 910 enters the first deflection magnet group 500 along the tangent direction of the input end of the first deflection magnet group 500, that is, the tangent direction of the input end of the first deflection magnet group 500 coincides with the conveying direction of the particle beam output by the synchrotron 400. The first deflection magnet group 500 is arc-shaped, and the output end of the first deflection magnet group 500 extends toward the side of the rotating support device 200 away from the first conveying channel 910, and the output end of the first deflection magnet group 500 or the extension line of the output end of the first deflection magnet group 500 crosses the rotating support device 200, and the second deflection magnet group 600 is connected to the first deflection magnet group 500. That is, the movement trajectory of the particle beam in the first deflection magnet group 500, or the extension line of its movement trajectory, crosses over the top of the rotating support device 200, so that the particle beam is output toward the side of the rotating support device 200 away from the first conveying channel 910, thereby reducing the axial length of the particle beam therapy device, thereby further reducing the overall area of ​​the particle beam therapy device, which is conducive to the overall miniaturization of the particle beam therapy device.

[0063] The axial direction mentioned above and below refers to the length direction of the rotation center line 14 of the rotation support device 200 .

[0064] Specifically, combined Figure 3 and Figure 8As shown, in some embodiments, the motion trajectory of the particle beam in the first deflection magnet group 500 crosses over the top of the rotating support device 200, so that the output end of the first deflection magnet group 500 is located on the side of the rotating support device 200 away from the first delivery channel 910. In other embodiments, the extension line of the motion trajectory of the particle beam in the first deflection magnet group 500 crosses over the top of the rotating support device 200, wherein the extension line at this location is the extension line along the circumferential direction of the particle beam motion trajectory. This design method makes the output end of the first deflection magnet group 500 located above the rotating support device 200, and further makes the connection between the first deflection magnet group 500 and the second deflection magnet group 600 located above the rotating support device 200, and the connection refers to the position where the second deflection magnet group 600 is directly connected to the first deflection magnet group 500, or the position where the second deflection magnet group 600 is connected to the first deflection magnet group 500 through a connecting pipe. The output end of the first deflection magnet group 500 may also be located on the side of the rotating support device 200 connected to the first conveying channel 910. It is worth noting that, in this design method, after the second deflection magnet group 600 is connected to the first deflection magnet group 500, the second deflection magnet group 600 can cross the rotating support device 200, so that the output end of the second deflection magnet group 600 is located on the side of the rotating support device 200 away from the first conveying channel 910.

[0065] The first deflection magnet group 500 and the second deflection magnet group 600 have the same number of deflection magnet bodies or at least partial structures and parameters as the deflection magnet group in the synchrotron 400 , and can be designed according to actual needs to meet the requirements of the preferred solution.

[0066] In some embodiments, in combination Figures 1 to 5 As shown, the first deflection magnet group 500 includes a plurality of deflection magnet bodies. For example, in the illustrated embodiment, the first deflection magnet group 500 includes four second deflection magnet bodies 510. The four second deflection magnet bodies 510 are used to deflect the particle beam through its magnetic field, so that the particle beam is output from the first deflection magnet group 500 in a set direction. Accordingly, the use of four second deflection magnet bodies 510 can deflect the particle beam by 90°, thereby making the particle beam output by the first deflection magnet group 500 extend obliquely upward. Of course, the second deflection magnet bodies 510 can also be other numbers, such as the number of the second deflection magnet bodies 510 can also be one, and the center angle of the second deflection magnet body 510 at the corresponding position in the second deflection magnet group 500 can be the same as or different from the center angle of the first deflection magnet body 410 at the corresponding position in the deflection magnet group of the synchrotron 400, which is designed according to specific needs. The center angle is the center angle of the arc formed by the beam motion trajectory on the surface where the deflection magnet body or the deflection magnet group is located.

[0067] In other embodiments, in combination Figure 7 , Figure 8 and Fig. 9 As shown, the deflection angle of the first deflection magnet group 500 is greater than 90°, so that the output direction of the particle beam output by the first deflection magnet group 500 is horizontal or parallel to the upper surface of the base, that is, the tangent direction of the output end of the first deflection magnet group 500 is horizontal or parallel to the support surface of the base, so that the tangent direction of the output end of the first deflection magnet group 500 is horizontal or parallel to the support surface of the base. At this time, the number of deflection magnet bodies in the first deflection magnet group 500 can be four or more than four. When the number of deflection magnet bodies in the first deflection magnet group 500 is four, the center angle of at least one deflection magnet body is greater than the center angle of the deflection magnet body at the corresponding position in the deflection magnet group of the synchrotron 400. When the number of deflection magnet bodies in the first deflection magnet group 500 is more than four, the number of deflection magnet bodies is preferably five, thereby saving material costs. Preferably, the plane 11 of the first deflection magnet group and the plane 12 of the second deflection magnet group can be made coplanar by adjusting the inclination angle of the plane 10 where the synchrotron is located or adjusting the inclination angle of the first delivery channel 910 relative to the plane 10 where the synchrotron is located. Of course, the curvature radius of the first deflection magnet group 500 or the second deflection magnet group 600 can also be adjusted to achieve coplanarity, but the first deflection magnet group 500 or the second deflection magnet group 600 with a changed curvature radius cannot be controlled in the same way as the deflection magnet group in the synchrotron 400. This design method makes the beam trajectories of the first deflection magnet group 500 and the second deflection magnet group 600 coplanar, making the overall design and installation of the particle beam therapy device more convenient, and the particle beam output by the first deflection magnet group 500 can directly enter the second deflection magnet group 600, without the need to set up deflection magnets and focusing magnets, further reducing the axial length of the particle beam therapy device.

[0068] It is worth noting that the tangent in the above and below texts refers to the tangent to the trajectory formed by the direction of movement of the particle beam.

[0069] The second deflection magnet group 600 is used to receive and transmit the particle beam output by the first deflection magnet group 500. The second deflection magnet group 600 is arc-shaped. The particle beam output by the first deflection magnet group 500 enters the second deflection magnet group 600 along the tangent direction of the input end of the second deflection magnet group 600, that is, the conveying direction of the particle beam output by the first deflection magnet group 500 is parallel to the tangent direction of the input end of the second deflection magnet group 600, or the particle beam output by the first deflection magnet group 500 is parallel to the tangent direction of the input end of the second deflection magnet group 600 after being deflected by the deflection magnet. It is designed according to specific needs. The output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotating support device 200. In the embodiment in which the input end of the second deflection magnet group 600 is horizontal and the output end is vertical, the second deflection magnet group 600 can directly adopt the same deflection magnet group as the synchrotron 400, that is, the structure, parameters and number of deflection magnet bodies are the same, simplifying the control system. Further optimized, the plane where the second deflection magnet group 600 is located is perpendicular to the horizontal plane or the supporting surface of the base. The second deflection magnet group 600 includes a plurality of deflection magnet bodies, and the deflection magnet body in the second deflection magnet group 600 can also be one. In some preferred embodiments, as shown in the embodiment, the second deflection magnet group 600 includes four third deflection magnet bodies 610, and the four third deflection magnet bodies 610 are used to deflect the particle beam through its magnetic field so that the particle beam is output toward the direction of the rotation center line 14 of the rotating support device 200.

[0070] In some preferred embodiments, Figures 1 to 7 As shown, the first deflection magnet group 500 and the second deflection magnet group 600 have the same structure and parameters as the deflection magnet group in the synchrotron 400, as well as the number of deflection magnet bodies, so that the number of second deflection magnet bodies 510 and the number of third deflection magnet bodies 610 are the same as the number of first deflection magnet bodies 410 of each deflection magnet group in the synchrotron 400, and the curvature radius of the deflection portion formed by the deflection magnets in the first deflection magnet group 500 and the second deflection magnet group 600 is the same as the curvature radius of the deflection portion formed by the deflection magnets in the synchrotron 400. Therefore, the first deflection magnet group 500 and the second deflection magnet group 600 can directly adopt the deflection magnet group in the synchrotron 400, making the overall design and installation of the particle beam therapy device more convenient. In addition, substantially the same control parameters can be used to control the deflection of the beam, thereby reducing the difficulty and complexity of deflection control of the beam path for irradiating the patient after the beam is drawn out from the synchrotron 400, and simplifying the control system.

[0071] The deflection magnet bodies in the first deflection magnet group 500, the deflection magnet bodies in the second deflection magnet group 600, and the deflection magnet bodies in the synchrotron 400 all have focusing edges. That is, the synchrotron 400, the first deflection magnet group 500, and the second deflection magnet group 600 are all composed of a plurality of deflection magnet bodies with focusing edges, which have a focusing function while realizing the deflection of the particle beam, and can omit a separate focusing magnet, thereby greatly reducing the overall volume and weight of the particle therapy device, making the rotation drive of the vertically arranged particle beam therapy device simpler and not requiring a higher-power rotation drive when rotating, and at the same time facilitating the precision control of the rotation motion. It is worth noting that the first deflection magnet group 500 and the second deflection magnet group 600 can also use magnets without edge focusing function, and cooperate with a separate focusing magnet for focusing.

[0072] The irradiation head 800 is connected to the end of the second deflection magnet group 600 , and the particle beam is emitted from the irradiation head 800 to the target tissue. In a further optimized manner, a focusing magnet may be provided between the irradiation head 800 and the second deflection magnet group 600 .

[0073] In other embodiments, the number of the first deflection magnet bodies 410 of each deflection magnet group in the synchrotron 400 may be one, in which case the number of the second deflection magnet bodies 510 and the number of the third deflection magnet bodies 610 should also be one. Specifically, one deflection magnet body realizes a 90° deflection, wherein the synchrotron requires four first deflection magnet bodies 410 to complete one rotation of the beam. Or one deflection magnet body realizes a 60° deflection, wherein the synchrotron requires six first deflection magnet bodies 410 to complete one rotation of the beam. It can be seen that the deflection angle of the deflection magnet body is not limited, and it only needs to meet the deflection requirements, and the number of deflection magnet bodies in the synchrotron should enable the beam to rotate once. It should be noted that each deflection magnet body in this embodiment needs to be provided with a separate focusing magnet before and after to avoid beam divergence.

[0074] Compared with the structure in which the synchrotron 400 and the beam transport device are arranged separately, the synchrotron 400, the first deflection magnet group 500 and the second deflection magnet group 600 integrated on the rotating support device 200 can significantly save space. Moreover, the particle beam output by the synchrotron 400 enters the first deflection magnet group 500 along the tangent direction of the input end of the first deflection magnet group 500, so there is no need to set a deflection magnet and a focusing magnet at the input end of the first deflection magnet group 500, so that the overall height of the particle beam therapy device is reduced, and the first deflection magnet group 500 extends toward the side of the rotating support device 200 away from the first transport channel 910 and crosses the rotating support device 200, so that the overall axial length of the particle beam therapy device is reduced. The reduction in height and length can reduce the space occupied by the particle beam therapy device, thereby saving the overall construction cost and construction difficulty of the building that accommodates the particle beam therapy device, and realizing an ultra-miniaturized synchrotron 400 particle beam therapy device.

[0075] Combination Figure 1 , Figure 3 , Figure 5 , Figure 8 and Fig. 9 As shown, the first delivery channel 910 extends from the middle of the synchrotron 400 and extends obliquely upward, thereby allowing the particle beam to be transported obliquely upward. The connection between the first deflection magnet group 500 and the second deflection magnet group 600 is located above the rotation centerline 14 of the rotation support device 200, and the output end of the second deflection magnet group 600 points to the rotation centerline 14 of the rotation support device 200, so as to facilitate the emission of the particle beam from top to bottom.

[0076] In some embodiments, the number of the second deflection magnet bodies 510 is four, so that the particle beam is deflected by 90° through the first deflection magnet group 500. Figure 1 , Figure 3 , Figure 4As shown in Figure 5, in order to ensure that the particle beam output by the first deflection magnet group 500 enters along the tangential direction of the input end of the second deflection magnet group 600, the first deflection magnet 902 is connected to the output end of the first deflection magnet group 500, so as to simplify the structure. Further optimized, a second delivery channel 900 is provided between the first deflection magnet group 500 and the second deflection magnet group 600, and the particle beam deflected by the first deflection magnet 902 enters the second delivery channel 900 along the beam delivery direction of the second delivery channel 900, and the output end of the second delivery channel 900 is tangent to the connection of the second deflection magnet group 600. The length of the second delivery channel 900 is set according to the demand, so that the output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotating support device 200. In order to prevent the deflected particle beam from diverging, a first focusing magnet 901 is disposed at the periphery of the second transport channel 900 . When the length of the second transport channel 900 is relatively large, there are multiple first focusing magnets 901 , which are disposed at intervals.

[0077] When the number of the first deflection magnet body 510 and the second deflection magnet body 610 are both 4, the length of the second delivery channel 900 can be shortened by setting the first deflection magnet 902 and the first focusing magnet 901, thereby reducing the axial length of the particle beam therapy device. If the radiation of the synchrotron 400 and the injection device 300 is too large during treatment, it is necessary to control the distance between the synchrotron 400 and the patient not to be too small, and to add a shielding device. At this time, the length of the second delivery channel 900 should be adjusted as needed.

[0078] Further optimized, the first deflection magnet 902 deflects the particle beam output by the first deflection magnet group 500 to the horizontal direction or parallel to the support surface of the base. This design makes the tangent direction of the input end of the second deflection magnet group 600 parallel to the horizontal direction or the support surface of the base, so that the particle beam output by the second deflection magnet group 600 is perpendicular and points to the rotation center line 14 of the rotating support device 200, which can make the particle beam basically perpendicular to the support surface of the patient lying flat and the virtual central axis where it is located. The central axis can be set to pass through the patient's tumor position and the rotation center line 14, preferably colinear with the rotation center line 14. After the synchrotron 400 is rotated, the beam can be rotated on a vertical plane perpendicular to the support surface and the virtual central axis where the patient's torso is located.

[0079] The plane where the first deflection magnet group 500 is located forms an angle with the plane where the second deflection magnet group 600 is located. The second deflection magnet group 600 can thus deflect the particle beam downward. At the same time, because the plane where the first deflection magnet group 500 is located has a certain angle with the plane where the second deflection magnet group 600 is located, in order to avoid the particle beam from diverging, a plurality of first focusing magnets 901 are arranged between the first deflection magnet group 500 and the second deflection magnet group 600. Specifically, since the first deflection magnet group 500 and the second deflection magnet group 600 are connected through the second delivery channel 900, the first focusing magnet 901 is arranged on the periphery of the second delivery channel 900, wherein the first focusing magnet 901 may be one, two or more, and is designed according to the length of the second delivery channel 900. Of course, under the premise of ensuring that beam focusing can be achieved, and during treatment, the radiation of the synchrotron 400, the injection device 300, etc. is not too large or can be reduced to an allowable range after shielding by necessary radiation shielding devices, in order to reduce the length of the second delivery channel 900, the number of the first focusing magnet 901 is as small as possible. In the scheme of some embodiments of the present patent, the radiation of the synchrotron 400, the injection device 300, etc. itself is within the allowable range, or can be reduced to the allowable range after shielding.

[0080] The first deflection magnet group 500 deflects the particle beam from the delivery direction of the first delivery channel 910 to the set direction, the first deflection magnet 902 turns the direction of the particle beam output from the first delivery channel 910 to the horizontal direction, and the second deflection magnet group 600 can turn the particle beam from the horizontal direction to the vertical direction, which can simplify the structure of the particle beam therapy device and facilitate installation, and avoid the angle between the second delivery channel 900 and the reference object cannot be accurately positioned during installation, resulting in installation errors, and then causing treatment accidents during treatment by the particle beam therapy device. And this design method reduces the height of the first deflection magnet group 500 and the second deflection magnet group 600, thereby reducing the height of the overall particle beam therapy device, and further saving the volume of the building that accommodates the particle beam therapy device. It is worth noting that this design method should meet the requirements that the irradiation head 800 is above the rotation center line 14 of the rotating support device 200, and there is a certain distance between the irradiation head 800 and the rotation center line 14 of the rotating support device 200, so as to accommodate patients.

[0081] The plane where the particle beam deflected by the first deflection magnet 902 is located coincides with the plane where the first deflection magnet group 500 is located, that is, one of the planes where the particle beam deflected by the first deflection magnet 902 is located coincides with the plane where the particle beam motion track in the first deflection magnet group 500 is located. This design can better deflect the particle beam.

[0082] Combination Figure 5and Fig.15 As shown, the synchrotron 400 is connected to a first delivery channel 910, and the vertical plane 13 between the particle beam motion trajectory and the plane where the particle beam motion trajectory of the synchrotron 400 is located is tangent to the particle beam trajectory before being drawn out from the synchrotron 400, and the vertical plane 13 between the particle beam motion trajectory in the first delivery channel 910 and the plane where the particle beam motion trajectory in the synchrotron 400 is located is perpendicular to the horizontal plane or the supporting surface of the base, so that the particle beam can enter the first delivery channel 910. Figure 3 As shown, the output end of the first delivery channel 910 extends obliquely upward, the input end of the first deflection magnet group 500 is connected to the first delivery channel 910, and the connection between the first delivery channel 910 and the first deflection magnet group 500 is tangent. Among them, the output end of the first delivery channel 910 is inclined upward, so that the particle beam output by the first deflection magnet group 500 is above the rotation center line 14 of the rotating support device 200. Further optimized, the periphery of the first delivery channel 910 is provided with a second focusing magnet 911.

[0083] Combination Figure 6 and Fig.10 As shown, in this embodiment, the particle beam therapy device further includes a cylinder 220, which is a cylinder and is coaxially fixed with the rotating support device 200. The first deflection magnet group 500, the second delivery channel 900 and part of the second deflection magnet group 600 are located outside the cylinder 220, and the output end of the second deflection magnet group 600 passes through the side wall of the cylinder 220 and is inserted into the inside of the cylinder 220. The second deflection magnet group 600 is fixedly connected to the cylinder 220, thereby enhancing the stability of the second deflection magnet group 600, and the cylinder 220 also plays a role of physical isolation. In order to increase the stability of each device of the particle beam therapy device during the rotation process, a connecting arm or a connecting frame can be set on the outer periphery of the cylinder 220, and the first deflection magnet group 500, the second deflection magnet group 600, the first delivery channel 910, the second delivery channel 900, the irradiation head 800 and a plurality of focusing magnets are connected and fixed by the connecting arm or the connecting frame.

[0084] In other embodiments, when the axial length of the particle beam therapy device is small, it is not necessary to set the cylinder 220. In this case, the first deflection magnet group 500, the second deflection magnet group 600, the first delivery channel 910, the second delivery channel 900, the irradiation head 800 and the multiple focusing magnets need to be fixedly connected by a fixed connection device to increase the stability of the rotation process. The fixed connection device can also be a connecting arm or a connecting frame. Since the connecting arm and the connecting frame are both common in the prior art and their setting methods are diverse, they only need to be able to play a connecting and fixing role, so they are not described in detail in this embodiment.

[0085] The rotating support device 200 and the cylinder 220 are supported by the first support 110 and the second support 120. In some optional embodiments, the cylinder 220 can be a square cylinder, an elliptical cylinder or a prismatic cylinder. Of course, the cylinders 220 of these shapes will also be provided with cylindrical matching parts adapted to the arc tracks of the first support 110 and the second support 120.

[0086] It should be noted that, in this patent, the particle beam motion trajectory in the deflection magnet body or the deflection magnet group or the synchrotron 400 or the transport channel does not necessarily remain unchanged. In addition, when there are multiple deflection magnet bodies in the synchrotron 400 and the first deflection magnet group 500 or the second deflection magnet group 600, the beam motion trajectory in the connecting channel between the deflection magnet bodies is not necessarily an arc, so the center angle of the deflection magnet group mentioned in this patent is the center angle of a virtual arc, which is fitted by the motion trajectory of the beam in each deflection magnet body in the deflection magnet group.

[0087] In this article, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "comprises", "comprising" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the statement "comprising a ..." does not exclude the presence of other identical elements in the process, method, article or device including the element.

[0088] The above description is only a specific embodiment of the present disclosure, so that those skilled in the art can understand or implement the present disclosure. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present disclosure. Therefore, the present disclosure will not be limited to the embodiments described herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A particle beam therapy device for emitting a particle beam to a target tissue, characterized in that: include: A fixed support device (100) comprises a base, on which a driving rotation mechanism is provided, and is used as a support base; A synchrotron (400) is used to accelerate a particle beam, wherein the synchrotron (400) has a deflection magnet, and the synchrotron (400) is connected to a first transport channel (910), wherein the first transport channel (910) transports the particle beam obliquely upward; A rotating support device (200) is used to support the synchrotron (400), and the rotating support device (200) is rotatably arranged on the fixed support device (100); when the rotating support device (200) performs a rotating motion, it has a rotating center line (14), and the power provided by the driving rotation mechanism can cause the rotating support device (200) to rotate around the rotating center line (14); A first deflection magnet group (500) is arranged on the rotating support device (200) and is used to receive and transport the particle beam output from the first transport channel (910). The particle beam output from the first transport channel (910) enters the first deflection magnet group (500) along a tangent direction of the input end of the first deflection magnet group (500). The first deflection magnet group (500) is arc-shaped. The output end of the first deflection magnet group (500) extends toward a side of the rotating support device (200) away from the first transport channel (910). The output end of the first deflection magnet group (500) or an extension line of the output end of the first deflection magnet group (500) crosses the rotating support device (200). a second deflection magnet group (600) connected to the first deflection magnet group (500) and used for receiving and transmitting the particle beam output by the first deflection magnet group (500); the second deflection magnet group (600) is arc-shaped; the particle beam output by the first deflection magnet group (500) enters the second deflection magnet group (600) along a tangent direction of the input end of the second deflection magnet group (600); and the output end of the second deflection magnet group (600) points to the rotation center line (14) of the rotation support device (200); An irradiation head (800) connected to the end of the second deflection magnet group (600), and a particle beam is emitted from the irradiation head (800) to a target tissue; The first deflection magnet group (500) and the second deflection magnet group (600) have the same number of deflection magnet bodies or at least a portion of the structure and parameters as the deflection magnet group in the synchrotron (400); An annular structure is provided on both sides of the rotating support device (200), the annular structure is coaxial with the rotating support device (200), the annular structure is rotatably arranged on the fixed support device (100), and the outer diameter of the annular structure is smaller than the radial distance of the farthest radial point of the rotating support device (200).

2. The particle beam therapy device according to claim 1, characterized in that: The first deflection magnet group (500) and the second deflection magnet group (600) have the same structure and parameters as the deflection magnet group in the synchrotron (400) and the same number of deflection magnet bodies.

3. The particle beam therapy device according to claim 2, characterized in that: The output end of the first deflection magnet group (500) is connected to the first deflection magnet (902), and the particle ejection velocity deflected by the first deflection magnet (902) enters the second deflection magnet group (600) along the tangent direction of the input end of the second deflection magnet group (600).

4. The particle beam therapy device according to claim 3, characterized in that: A second transport channel (900) is provided between the first deflection magnet group (500) and the second deflection magnet group (600), and the particle ejection velocity deflected by the first deflection magnet (902) enters the second transport channel (900) along the beam transport direction of the second transport channel (900), and the output end of the second transport channel (900) is tangent to the connection point of the second deflection magnet group (600).

5. The particle beam therapy device according to claim 4, characterized in that: A first focusing magnet (901) is provided on the outer periphery of the second transport channel (900).

6. The particle beam therapy device according to claim 5, characterized in that: The first deflection magnet (902) deflects the particle beam output by the first deflection magnet group (500) to a horizontal direction or parallel to a supporting surface of the base.

7. The particle beam therapy device according to claim 1, characterized in that: The tangent direction of the output end of the first deflection magnet group (500) is horizontal or parallel to the support surface of the base; and / or the plane where the first deflection magnet group (500) is located is coplanar with the plane where the second deflection magnet group (600) is located.

8. The particle beam therapy device according to claim 1, characterized in that: The particle beam output by the second deflection magnet group (600) is perpendicular to the rotation center line (14) of the rotation support device (200); and / or the plane in which the second deflection magnet group (600) is located is perpendicular to the horizontal plane or the support surface of the base; and / or the rotation center line (14) of the rotation support device (200) is parallel to the horizontal plane or the support surface of the base.

9. The particle beam therapy device according to claim 1, characterized in that: The plane where the first deflection magnet group (500) is located forms an angle with the plane where the second deflection magnet group (600) is located.

10. The particle beam therapy device according to claim 1, characterized in that: The deflection magnet bodies in the first deflection magnet group (500), the deflection magnet bodies in the second deflection magnet group (600), and the deflection magnet bodies of the deflection magnet group in the synchrotron (400) all have focusing edges.

11. The particle beam therapy device according to claim 1, characterized in that: The vertical plane (13) between the particle beam motion trajectory in the first delivery channel (910) and the plane where the particle beam motion trajectory in the synchrotron (400) is located is perpendicular to the horizontal plane or the support surface of the base; and / or the plane (10) where the particle beam motion trajectory in the synchrotron (400) is located is perpendicular to the support surface or the horizontal plane of the base.

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