Composition with blood-tonifying and qi-invigorating and weight-reducing effects

Abstract

The present invention relates to a composition having the effects of nourishing blood and replenishing qi and reducing weight. The raw materials for preparation include the following components: hawthorn, cassia seed, kudzu root, cinnamon bark, grape, salvia miltiorrhiza, psoralea corylifolia, wolfberry, eucommia bark, ginseng, vitamin A, vitamin B1, vitamin K, vitamin U, and folic acid. The rational combination of hawthorn, cassia seed, and kudzu root reduces the body's absorption and utilization of lipids. The composition of the present invention achieves a good weight loss effect, while also strengthening the body's foundation and nourishing the vital energy, consolidating and conditioning the body. On this basis, multiple vitamins are added to provide the body with vitamin intake in daily life and maintain the body's nutritional balance. The composition of the present invention can be directly ground into powder to obtain a finished product, or it can be extracted by a suitable method to obtain a better therapeutic effect.

Description

Technical Field

[0001] The present invention relates to the field of traditional Chinese medicine, and in particular to a composition with the effects of nourishing blood and qi and reducing weight. Background Art

[0002] Obesity is a chronic condition characterized by excessive fat accumulation and abnormal weight due to excessive food intake or altered metabolism, resulting in greater energy intake than energy expenditure. Currently, there are various criteria for determining obesity, including body mass index, standard weight calculation, waist-to-hip ratio, bioelectrical impedance, skinfold thickness, and density measurement. Generally, obesity is categorized as overweight, mild obesity, moderate obesity, and severe obesity, respectively, when an individual's weight exceeds their standard weight by 10%, 20%, 30%, or 50% or more.

[0003] Obesity can be divided into three types based on the cause: simple obesity, secondary obesity, and drug-induced obesity. Simple obesity, which is not caused by any disease and is not associated with any endocrine disorders or metabolic disorders, is the most common of the various obesity-related diseases. Simple obesity can be divided into two types based on the cause: acquired obesity and constitutional obesity. Acquired obesity occurs when the body consumes too much food, with the energy converted from food far exceeding the body's normal growth and metabolic needs. The excess energy is converted into fat and stored in fat cells, increasing their size and number. For women, especially postpartum women, fat accumulation is common due to excessive intake of high-fat foods during pregnancy and lack of exercise. Postpartum weakness prevents frequent exercise from burning off fat, resulting in excess fat accumulation, body deformation, and numerous potential health and aesthetic risks. Therefore, the development of safe and effective compositions with qi-tonifying and weight-loss benefits is essential.

[0004] Chinese patent application CN108967623A discloses a slimming wax gourd and lotus leaf health tea and its preparation method. The tea is made from 60-80 parts of cassia seeds, 10-20 parts of wax gourd peel, 5-12 parts of lotus leaves, 1-8 parts of rose flowers, 2-5 parts of hawthorn, 1-3 parts of lemon slices, 1-2 parts of liquorice, 1-2 parts of raw malt, 1-2 parts of dried lily bulbs, 1-2 parts of bitter melon slices, and 1-2 parts of pumpkin flowers. The tea is a pure Chinese herbal formula with a reasonable formula, a comfortable taste, and a unique flavor. It is a pure natural beverage that not only has rich nutritional value but also has excellent health care effects. The various raw materials interact with each other and have multiple functions such as nourishing blood and qi, beautifying the skin, reducing weight and reducing fat, moisturizing the intestines and promoting bowel movements, and clearing away heat and dampness. The tea has no side effects when consumed long-term, is green and healthy, has the effect of slimming and improving the complexion, and is low in cost and suitable for promotion.

[0005] Chinese patent application CN106309795A discloses a traditional Chinese medicine pill for health preservation and weight loss, comprising the following ingredients by weight: 24% rhubarb powder, 1.6% safflower pollen, 8% cassia seed, 8% kelp, 3.2% angelica root, 2.4% chicken's gizzard lining, 8% radish seed, 2.4% konjac, 40% honey, 0.8% mint, 0.8% borneol, and 0.8% sodium carboxymethyl starch or low-substituted hydroxypropyl cellulose. Honey, when applied externally, moisturizes the skin, has antibacterial and anti-inflammatory properties, promotes weight loss, and promotes sleep; safflower pollen smoothes and refines the skin; angelica root nourishes and invigorates blood circulation; konjac effectively prevents and treats obesity; kelp softens and dissolves lumps, eliminates phlegm, and promotes diuresis; borneol treats symptoms such as coma and persistent ulcers caused by closed syndrome. Cassia seed lowers blood pressure and blood lipids; chicken's gizzard lining strengthens the stomach and digests, and relieves stranguria and dissolves stone; and rhubarb powder clears heat and promotes bowel movements. The health-preserving and weight-loss Chinese medicine pill does not require massage, is easy to use, has significant fat-burning and weight-loss effects, is suitable for individual operation, and has a simple manufacturing process and low cost, adding a new variety to the fashionable slimming and weight-loss essential oils. Summary of the Invention

[0006] The purpose of the present invention is to provide a composition with the effects of nourishing blood and qi and losing weight in view of the overall shortcomings of the existing technology.

[0007] The purpose of the present invention is achieved through the following solutions.

[0008] A composition with the effects of nourishing blood and qi and reducing weight, wherein the raw materials for preparation include the following components in parts by weight:

[0009] 5-20 parts of hawthorn, 5-12 parts of cassia seed, 5-10 parts of kudzu root, 12-25 parts of cinnamon, 5-10 parts of grape, 5-10 parts of salvia miltiorrhiza, 5-20 parts of psoralea corylifolia, 5-20 parts of wolfberry, 6-10 parts of eucommia bark, 5-10 parts of ginseng, 0.002-0.006 part of vitamin A, 0.001-0.003 part of vitamin B1, 0.0002-0.0006 part of vitamin K, 0.2-0.6 part of vitamin U and 0.001-0.01 part of folic acid.

[0010] Furthermore, the composition, in parts by weight, is prepared from raw materials comprising the following components:

[0011] 12 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 8 parts of grape, 7 parts of salvia miltiorrhiza, 15 parts of psoralea corylifolia, 15 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 part of vitamin A, 0.002 part of vitamin B1, 0.0004 part of vitamin K, 0.4 part of vitamin U and 0.05 part of folic acid.

[0012] The composition of the present invention can be prepared by directly mixing and grinding the raw materials in the aforementioned amounts.

[0013] A method for preparing the composition comprises mixing the raw materials in the aforementioned parts by weight and grinding the mixture into powder.

[0014] Furthermore, the grinding is to grind into powder of 60-100 mesh.

[0015] The composition of the present invention can also be obtained by using the above-mentioned raw materials in parts by weight through a suitable extraction method.

[0016] A method for preparing the composition comprises the following steps:

[0017] S1: Hawthorn, Cassia seed and Pueraria root were mixed and ground into powder, and then extracted with water, filtered and dried to obtain extract A;

[0018] S2: Extract B obtained by mixing cinnamon bark, grapes, and salvia miltiorrhiza and grinding them into powder, followed by ethanol extraction, filtration, and drying;

[0019] S3: Grind the psoralea corylifolia, wolfberry, eucommia bark and ginseng into powder to obtain powder C;

[0020] S4: extract A, extract B, powder C, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid are mixed and ground into powder to obtain the composition.

[0021] Furthermore, in S1, the grinding is to grind the mixture into 60-100 mesh powder.

[0022] Furthermore, in S1, the water extraction is performed with a water amount of 10-15 times the total weight of the S1 raw materials, at a temperature of 80-100° C. for 4-6 hours.

[0023] Furthermore, in S2, the grinding is to grind the mixture into 60-100 mesh powder.

[0024] Furthermore, in S2, the ethanol extraction is performed by using ethanol in an amount of 20-25 times the total weight of the S2 raw material, at a temperature of 50-70° C. for 4-6 hours.

[0025] Furthermore, in S3, the grinding is to grind the mixture into 20-40 mesh powder.

[0026] Furthermore, in S4, the grinding is to grind the mixture into 60-100 mesh powder.

[0027] The advantages of the present invention are:

[0028] 1. The rational combination of hawthorn, cassia seed, and kudzu root reduces the body's absorption and utilization of lipids. The combination of cinnamon bark, hawthorn, grapes, and salvia miltiorrhiza nourishes and invigorates blood circulation. Their combined effects synergize to achieve a superior weight loss effect. Meanwhile, psoralea corylifolia, wolfberry, eucommia bark, and ginseng strengthen the body's foundation and vital energy, consolidating and conditioning the body. Furthermore, the addition of multiple vitamins provides daily vitamin intake and maintains nutritional balance.

[0029] 2. The composition of the present invention can be directly ground into powder to obtain a finished product, or a better therapeutic effect can be obtained through a suitable extraction method. It is speculated that this may be due to the complex composition of traditional Chinese medicine. After combining different drugs, some substances that inhibit the efficacy of the drugs can be removed through appropriate extraction methods. DETAILED DESCRIPTION

[0030] The raw materials used in the embodiments of the present invention are all commercially available dry products with a water content of 5-15%.

[0031] Example 1

[0032] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0033] 5 parts of hawthorn, 12 parts of cassia seeds, 10 parts of kudzu root, 15 parts of cinnamon bark, 5 parts of grape, 5 parts of salvia miltiorrhiza, 20 parts of psoralea corylifolia, 5 parts of wolfberry, 10 parts of eucommia bark, 5 parts of ginseng, 0.002 parts of vitamin A, 0.003 parts of vitamin B1, 0.0006 parts of vitamin K, 0.2 parts of vitamin U and 0.01 parts of folic acid.

[0034] The raw materials of each component are dried, mixed, and ground together into 80-mesh powder to obtain the composition, with a total amount of 85 parts.

[0035] Example 2

[0036] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0037] 20 parts of hawthorn, 5 parts of cassia seeds, 5 parts of kudzu root, 25 parts of cinnamon bark, 10 parts of grapes, 10 parts of salvia miltiorrhiza, 5 parts of psoralea corylifolia, 5 parts of wolfberry, 6 parts of eucommia bark, 10 parts of ginseng, 0.006 parts of vitamin A, 0.001 parts of vitamin B1, 0.0002 parts of vitamin K, 0.6 parts of vitamin U and 0.001 parts of folic acid.

[0038] The raw materials of each component were dried, mixed, and ground together into 80-mesh powder to obtain the composition, with a total amount of 93 parts.

[0039] Example 3

[0040] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0041] 12 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 8 parts of grape, 7 parts of salvia miltiorrhiza, 15 parts of psoralea corylifolia, 15 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 part of vitamin A, 0.002 part of vitamin B1, 0.0004 part of vitamin K, 0.4 part of vitamin U and 0.05 part of folic acid.

[0042] The raw materials of each component are dried, mixed, and ground together into 80-mesh powder to obtain the composition, with a total amount of 95 parts.

[0043] Example 4

[0044] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0045] 12 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 8 parts of grape, 7 parts of salvia miltiorrhiza, 15 parts of psoralea corylifolia, 15 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 part of vitamin A, 0.002 part of vitamin B1, 0.0004 part of vitamin K, 0.4 part of vitamin U and 0.05 part of folic acid.

[0046] The composition is prepared by the following steps:

[0047] S1: Mix the hawthorn, cassia seed and kudzu root in water and grind into 80 mesh powder, add 10 times the weight of water as the total weight of the raw materials in this step, heat to 80°C, extract for 6 hours, filter while hot, recover the filtrate, concentrate and dry to obtain extract A;

[0048] S2: Grind the cinnamon bark, grapes, and salvia miltiorrhiza (Danshen) in the aforementioned weight portions into 80-mesh powder, add 20 times the weight of ethanol as the total weight of the raw materials in this step, heat to 50° C., extract for 6 hours, filter while hot, recover the filtrate, concentrate, and dry to obtain extract B;

[0049] S3: Grind the weight portions of psoralea corylifolia, wolfberry, eucommia bark and ginseng into a powder of 30 mesh to obtain powder C;

[0050] S4: extract A, extract B, powder C, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid are mixed and ground into 80 mesh to obtain the composition, with a total of 48 parts.

[0051] Example 5

[0052] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0053] 12 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 8 parts of grape, 7 parts of salvia miltiorrhiza, 15 parts of psoralea corylifolia, 15 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 part of vitamin A, 0.002 part of vitamin B1, 0.0004 part of vitamin K, 0.4 part of vitamin U and 0.05 part of folic acid.

[0054] The composition is prepared by the following steps:

[0055] S1: Mix the weight portions of hawthorn, cassia seed and kudzu root with water and grind into 80 mesh powder, add 15 times the weight portion of water of the total weight of the raw materials in this step, heat to 100°C, extract for 4 hours, filter while hot, recover the filtrate, concentrate and dry to obtain extract A;

[0056] S2: Grind the cinnamon bark, grapes, and salvia miltiorrhiza (Danshen) by weight into 80-mesh powder, add 25 times the weight of ethanol as the total weight of the raw materials in this step, heat to 70° C., extract for 4 hours, filter while hot, recover the filtrate, concentrate, and dry to obtain extract B;

[0057] S3: Grind the weight portions of psoralea corylifolia, wolfberry, eucommia bark and ginseng into a powder of 30 mesh to obtain powder C;

[0058] S4: extract A, extract B, powder C, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid were mixed and ground into 80 mesh to obtain the composition, with a total amount of 52 parts.

[0059] The difference between Comparative Example 1 and Example 5 is that only water is used to extract

[0060] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0061] 12 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 8 parts of grape, 7 parts of salvia miltiorrhiza, 15 parts of psoralea corylifolia, 15 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 part of vitamin A, 0.002 part of vitamin B1, 0.0004 part of vitamin K, 0.4 part of vitamin U and 0.05 part of folic acid.

[0062] The composition is prepared by the following steps:

[0063] S1: Mix the raw materials except vitamins according to the weight parts, grind into 80 mesh, add 15 times the weight parts of water of the total raw materials, heat to 100°C, extract for 4 hours, filter while hot, recover the filtrate, concentrate, and dry to obtain extract A;

[0064] S2: The extract A, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid were mixed and ground into 80 meshes to obtain the composition, with a total of 24 parts.

[0065] The difference between Comparative Example 2 and Example 5 is that only alcohol extraction is used.

[0066] S1: Mix the raw materials except vitamins according to the weight parts, grind to 80 mesh, add 25 times the weight parts of water as the total weight of the raw materials, heat to 70°C, extract for 4 hours, filter while hot, recover the filtrate, concentrate, and dry to obtain extract A;

[0067] S2: The extract A, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid were mixed and ground into 80 meshes to obtain the composition, with a total of 35 parts.

[0068] The difference between Comparative Example 3 and Example 5 is that the raw material ratio is different

[0069] Composition with blood-tonifying and qi-invigorating and weight-reducing effects

[0070] 27 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 18 parts of grapes, 7 parts of salvia miltiorrhiza, 5 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 parts of vitamin A, 0.002 parts of vitamin B1, 0.0004 parts of vitamin K, 0.4 parts of vitamin U and 0.05 parts of folic acid.

[0071] The composition is prepared by the following steps:

[0072] S1: Mix the weight portions of hawthorn, cassia seed and kudzu root with water and grind into 80 mesh powder, add 15 times the weight portion of water of the total weight of the raw materials in this step, heat to 100°C, extract for 4 hours, filter while hot, recover the filtrate, concentrate and dry to obtain extract A;

[0073] S2: Grind the cinnamon bark, grapes, and salvia miltiorrhiza (Danshen) by weight into 80-mesh powder, add 25 times the weight of ethanol as the total weight of the raw materials in this step, heat to 70° C., extract for 4 hours, filter while hot, recover the filtrate, concentrate, and dry to obtain extract B;

[0074] S3: Grind the wolfberry, eucommia bark and ginseng in the amounts by weight into a powder of 30 mesh to obtain powder C;

[0075] S4: extract A, extract B, powder C, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid are mixed and ground into 80 mesh to obtain the composition, with a total amount of 32 parts.

[0076] Effect Example 1 - Verification of Blood-enriching Effect (Refer to "Technical Specifications for Inspection and Evaluation of Health Food (2003 Edition)")

[0077] Effects of the product on free protoporphyrin and hemoglobin

[0078] Experimental animals: SPF-grade newly weaned female SD rats, 5 in each group, fed with the feed of formula 1 in the Technical Specifications for Inspection and Evaluation of Health Food (2003 Edition).

[0079] Sample dosage: Oral gavage once a day at a fixed time;

[0080] All test samples were administered orally, wherein the dosage ratio was calculated based on the amount of raw materials used and the amount remaining after preparation, with Example 3 as the benchmark.

[0081] Example 3: Dosage 0.5 g / kg . BW;

[0082] Example 5: Dosage 0.27 g / kg . BW;

[0083] Comparative Example 1: Dosage 0.13 g / kg . BW;

[0084] Comparative Example 2: Dosage 0.18 g / kg . BW;

[0085] Comparative Example 3: Dosage 0.17 g / kg . BW.

[0086] The low iron control group was gavaged with distilled water without the test article.

[0087] Experimental period: four weeks.

[0088] Table 1 Effects on free protoporphyrin in experimental rats (unit: μg / L)

[0089] Before the experiment After the experiment Example 3 94.2±8.2 75.4±7.3** Example 5 93.8±7.9 72.5±7.6** Comparative Example 1 94.7±6.9 85.8±8.1* Comparative Example 2 92.1±7.1 83.1±7.2* Comparative Example 3 90.3±8.8 79.1±8.5* Low iron control group 93.5±7.8 96.3±8.7

[0090] Compared with the control group, *P<0.05, **P<0.01.

[0091] The free protoporphyrin in the erythrocytes of the rats in each experimental group showed a significant decrease compared with the control group, and the decrease in each embodiment was greater than that in each comparative example.

[0092] Table 2 Effects on hemoglobin in experimental rats (unit: g / L)

[0093] Before the experiment After the experiment Example 3 78.1±11.8 116.2±12.0**- Example 5 77.3±13.2 121.6±13.8** Comparative Example 1 79.6±12.6 93.2±12.1* Comparative Example 2 76.3±10.8 98.1±11.2** Comparative Example 3 79.3±11.1 104.5±11.7* Low iron control group 80.2±12.2 77.7±11.5

[0094] Compared with the control group, *P<0.05, **P<0.01.

[0095] It can be seen that there was no significant difference in the hemoglobin content of the rats in each group before the experiment. After the experiment, the hemoglobin content of each example was significantly increased compared with the control group, and the increase was greater than that of each control group.

[0096] In summary, the composition provided by the present invention has the effect of enriching blood.

[0097] Effect Example 2- Weight Loss Effect Verification

[0098] According to the auxiliary blood lipid lowering function test method in the "Technical Specifications for Inspection and Evaluation of Health Food (2003 Edition)", a high-fat diet was used for modeling. The specific plan is as follows:

[0099] SPF female SD rats, with an average weight of about 180 g, 6 rats in each group, were divided into a basic control group, a high-fat control group, Example 3, Example 5, Comparative Example 1, Comparative Example 2 and Comparative Example 3.

[0100] The basal control group used basal feed, and the high-fat control group used high-fat feed;

[0101] The groups of Example 3, Example 5, Comparative Example 1, Comparative Example 2 and Comparative Example 3 were fed with a high-fat diet and given the drug by gavage at the same time every day, with a dosage of 0.5 g / kg . BW.

[0102] The experimental period was 30 days. On day 31, rats were fasted for 16 hours and sacrificed by cervical dislocation. The livers were removed and weighed, and the liver index (liver weight to body weight) was calculated. The abdominal fat, including abdominal fat, perirenal fat, and periepididymal fat, was carefully removed and weighed. The fat index (total abdominal fat weight to body weight) was calculated.

[0103] Experimental results:

[0104] Table 3 Liver index and fat index of rats after the experiment

[0105] Liver weight (g) Liver index (%) Fat index (%) Basic control group 12.31±1.13** 3.47±0.38** 1.43±0.66** High-fat control group 17.62±2.35 4.18±0.47 2.46 Example 3 14.16±1.57** 3.76±0.32** 1.72±0.53** Example 5 13.52±0.98** 3.70±0.41** 1.65±0.49** Comparative Example 1 15.58±2.16* 4.02±0.52* 2.03±0.61* Comparative Example 2 15.71±1.68* 4.11±0.44 1.95±0.55* Comparative Example 3 14.89±1.44* 3.92±0.33* 1.98±0.50*

[0106] Compared with the high-fat control group, *P<0.05, **P<0.01.

[0107] Since obesity often causes an increase in liver weight and accumulation of body fat, it can be seen from the data in Table 3 that the composition provided by the present invention has a good weight loss effect.

[0108] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, rather than to limit the scope of protection of the present invention. Simple modifications or equivalent substitutions of the technical solution of the present invention by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the present invention.

Claims

1. A composition with the effects of nourishing blood and qi and reducing weight, wherein the raw materials for preparation are composed of the following components in parts by weight: 5-20 parts of hawthorn, 5-12 parts of cassia seed, 5-10 parts of kudzu root, 12-25 parts of cinnamon, 5-10 parts of grape, 5-10 parts of salvia miltiorrhiza, 5-20 parts of psoralea corylifolia, 5-20 parts of wolfberry, 6-10 parts of eucommia bark, 5-10 parts of ginseng, 0.002-0.006 part of vitamin A, 0.001-0.003 part of vitamin B1, 0.0002-0.0006 part of vitamin K, 0.2-0.6 part of vitamin U and 0.001-0.01 part of folic acid.

2. The composition according to claim 1, characterized in that The raw materials for preparation are composed of the following components in parts by weight: 12 parts of hawthorn, 9 parts of cassia seeds, 7 parts of kudzu root, 18 parts of cinnamon bark, 8 parts of grape, 7 parts of salvia miltiorrhiza, 15 parts of psoralea corylifolia, 15 parts of wolfberry, 8 parts of eucommia bark, 7 parts of ginseng, 0.004 part of vitamin A, 0.002 part of vitamin B1, 0.0004 part of vitamin K, 0.4 part of vitamin U and 0.05 part of folic acid.

3. A method for preparing the composition as claimed in claim 1 or 2, comprising mixing the raw materials in the aforementioned parts by weight and grinding them into powder.

4. The preparation method according to claim 3, characterized in that The grinding is to grind to powder of 60-100 mesh.

5. A method for preparing the composition according to claim 1 or 2, comprising the following steps: S1: Hawthorn, Cassia seed and Pueraria root were mixed and ground into powder, and then extracted with water, filtered and dried to obtain extract A; S2: Extract B, which is obtained by mixing and grinding cinnamon bark, grapes, and salvia miltiorrhiza, followed by ethanol extraction, filtration, and drying; S3: Grind the psoralea corylifolia, wolfberry, eucommia bark and ginseng into powder to obtain powder C; S4: extract A, extract B, powder C, vitamin A, vitamin B1, vitamin K, vitamin U and folic acid are mixed and ground into powder to obtain the composition.

6. The preparation method according to claim 5, characterized in that In S1, the grinding is to grind the mixture into 60-100 mesh powder.

7. The preparation method according to claim 5, characterized in that In S1, the water extraction is performed by using water in an amount of 10-15 times the total weight of the raw materials in S1, at a temperature of 80-100° C. for 4-6 hours.

8. The preparation method according to claim 5, characterized in that In S2, the grinding is to grind the mixture into 60-100 mesh powder.

9. The preparation method according to claim 5, characterized in that In S2, the ethanol extraction is performed by using ethanol in an amount of 20-25 times the total weight of the S2 raw material, at a temperature of 50-70° C. for 4-6 hours.

10. The preparation method according to claim 5, characterized in that In S3, the grinding is to grind the mixture into 20-40 mesh powder; in S4, the grinding is to grind the mixture into 60-100 mesh powder.