Single-sided driven drug infusion device

Abstract

The present invention discloses a drug infusion device with unilateral drive, comprising: a drug storage unit, a piston and a screw rod, the piston is connected to the screw rod and is arranged in the drug storage unit; a drive unit, the drive unit includes at least one rotating shaft and at least one drive component, the drive component includes at least one drive end; at least one drive wheel provided with teeth, the advancing drive end pushes the teeth to make the drive wheel rotate; a linear driver and a reset unit respectively connected to the drive component, the linear driver and the reset unit respectively apply acting forces to the drive component to make the drive ends advance and reset respectively; and at least two retaining walls, arranged on the same side of the drive unit, for defining the advancing position of the drive unit. Due to the arrangement of the retaining walls, the rotation amplitude of the drive component can be precisely controlled, the infusion accuracy of the infusion device is improved, the user can arbitrarily select a suitable infusion mode according to needs to precisely control the body fluid level, meet the user's needs, and improve the user experience.

Description

Technical Field

[0001] The present invention mainly relates to the field of medical devices, and particularly relates to a drug infusion device with unilateral drive. Background Art

[0002] A drug infusion device is a medical device that continuously injects drugs into a patient's body to achieve the purpose of disease treatment. The drug infusion device is widely used in the treatment of diabetes. Insulin is continuously infused into the patient's subcutaneous tissue according to the dose required by the human body to simulate the secretion function of the pancreas and thus maintain the stability of the patient's blood sugar. The drug fluid is usually stored inside the infusion pump body. The existing drug infusion devices usually directly paste the pump body on the patient's body with medical adhesive tape, and the patient operates a remote device for infusion.

[0003] Currently, the infusion accuracy of existing infusion devices is relatively low. The highest infusion accuracy is only limited to the unit infusion volume determined by the minimum step length of the driving wheel, and users or closed-loop systems cannot flexibly select infusion modes to meet the actual needs of the body for drugs.

[0004] Therefore, there is an urgent need in the prior art for a drug infusion device with high infusion accuracy. Summary of the Invention

[0005] An embodiment of the present invention discloses a drug infusion device with unilateral drive, which is provided with at least two retaining walls, can accurately control the rotation amplitude of the driving component, improve the infusion accuracy of the infusion device, and users or closed-loop systems can flexibly select different infusion modes to accurately control the body fluid level to meet the needs of the body.

[0006] The present invention discloses a drug infusion device with unilateral drive, including: a drug storage unit, a piston and a screw rod. The piston is arranged in the drug storage unit and is connected to the screw rod; a driving unit, the driving unit includes at least one rotating shaft and at least one driving component. The driving component includes at least one driving end, and the driving component rotates around the rotating shaft to make the driving end advance or reset; at least one driving wheel provided with teeth, the advancing driving end pushes the teeth to make the driving wheel rotate, and then drives the screw rod to advance; a linear driver and a reset unit respectively connected to the driving component, the linear driver and the reset unit respectively apply forces to the driving component to make the driving end advance and reset respectively; at least two retaining walls, the retaining walls are arranged on the same side of the driving unit and are used to define the advancing position of the driving unit.

[0007] According to one aspect of the present invention, the retaining wall is an elastic conductive member.

[0008] According to one aspect of the present invention, it is a conductive spring, a conductive elastic sheet, a conductive rubber or a conductive silica gel.

[0009] According to one aspect of the present invention, the linear driver includes an electrically driven linear driver or an electrically heated linear driver.

[0010] According to one aspect of the present invention, the reset unit includes an electrically driven linear driver and an electrically heated linear driver.

[0011] According to one aspect of the present invention, at least one retaining wall is further provided on the other side of the driving unit.

[0012] According to one aspect of the present invention, a control unit is further included, which jointly controls the movement end point of the driving component with at least one retaining wall provided on the other side of the driving unit.

[0013] According to one aspect of the present invention, the reset unit is an elastic member, and the elastic member includes at least one or more of a spring, a shrapnel, an elastic plate, an elastic rod, or an elastic reset rubber.

[0014] According to one aspect of the present invention, the reset unit is an elastic conductive member.

[0015] According to one aspect of the present invention, the elastic conductive member includes a metal spring or a conductive rubber.

[0016] According to one aspect of the present invention, the driving component has a variety of different operating modes, so that the infusion device has a variety of different unit infusion volumes or infusion rates.

[0017] According to one aspect of the present invention, the operating modes of the driving component include the amplitude of reciprocating motion, the frequency of reciprocating motion, or the motion rate. The various different operating modes of the driving component include reciprocating motions with various different amplitudes or frequencies, or include various different motion rates.

[0018] According to one aspect of the present invention, a base is further included. The driving wheel is movably assembled on the base, and the base is in frictional cooperation with the driving wheel. When the driving end slides on the tooth surface, the driving wheel stops rotating.

[0019] According to one aspect of the present invention, a limiting component is further included. The limiting component is movably assembled on the base to limit the position of the driving wheel. The limiting component is in frictional cooperation with the driving wheel. When the driving end slides on the tooth surface, the driving wheel stops rotating.

[0020] Compared with the prior art, the technical solution of the present invention has the following advantages:

[0021] In the single-sided driving drug infusion device disclosed by the present invention, at least two retaining walls are provided, which can accurately control the rotation amplitude of the driving component, improve the infusion accuracy of the infusion device. Users or the closed-loop system can arbitrarily select a suitable infusion mode to accurately control the body fluid level, meet the user's needs, and improve the user experience.

[0022] Furthermore, the reset unit includes an electrically-driven linear driver, an electrically-heated linear driver, or an elastic member. The power output of the linear driver can be controlled by current, and the power output is more stable, thereby making the amplitude or rate of movement of the driving component stable and controllable. Additionally, when the reset unit is an elastic member, the driving component can automatically reset without consuming electrical energy, thus reducing the power consumption and cost of the infusion device.

[0023] Furthermore, the driving component has multiple different operating modes, thereby enabling the infusion device to have multiple different unit infusion volumes or infusion rates. When the infusion device has multiple different unit infusion volumes or infusion rates, according to the actual needs of the body, the user or the closed-loop system can arbitrarily select a suitable infusion mode to precisely control the body fluid level, further improving the user experience.

[0024] Furthermore, the infusion device further includes a base, and the base is in frictional engagement with the driving wheel. When the driving end slides on the tooth surface, the driving wheel stops rotating, improving the accuracy of the drug infusion volume and eliminating potential safety hazards.

[0025] Furthermore, the infusion device further includes a limiting component, which is movably assembled on the base to limit the position of the driving wheel, and the limiting component is in frictional engagement with the driving wheel. The limiting component can make full use of the internal space of the infusion device and is in frictional engagement with the driving wheel at multiple positions. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figures 1a - 1b A top view of a single-sided drive drug infusion device according to different embodiments of the present invention;

[0027] Figure 2 A schematic diagram of the main internal structure of the infusion unit according to an embodiment of the present invention;

[0028] Figures 3a - 3c A top view of the structure in which the driving end pushes the teeth to move according to different embodiments of the present invention;

[0029] Figures 4a - 4c A schematic diagram of the structure in which the linear driver and the reset unit cooperate with the driving component respectively according to different embodiments of the present invention;

[0030] Figures 5a - 5b A schematic diagram of the structure in which the pulling direction of the linear driver is not parallel to the advancing direction of the screw according to another embodiment of the present invention;

[0031] Figures 6a - 6c Schematic diagrams of the driving component in the initial position, half-way position, and full-way position respectively;

[0032] Figure 7 A schematic diagram of the change in the reciprocating rotation amplitude of the driving component according to an embodiment of the present invention;

[0033] Figures 8a - 8b Schematic diagram of the friction fit structure between the driving wheel and the base or the limiting component according to an embodiment of the present invention;

[0034] Figure 9 Schematic diagram of the coaxial structure of two driving components according to an embodiment of the present invention;

[0035] Figure 10 Schematic diagram of the structure of two non - coaxial driving components according to another embodiment of the present invention;

[0036] Figures 11a - 11b Schematic diagram of the structure in which the two driving ends of the driving component respectively cooperate with two driving wheels according to still another embodiment of the present invention;

[0037] Figures 12a - 12b Schematic diagram of the structure in which the driving component includes two driving ends arranged up and down according to yet another embodiment of the present invention. Detailed implementation manners

[0038] As mentioned above, the infusion accuracy of the existing infusion device is relatively low. The highest infusion accuracy is only limited to the unit infusion volume determined by the minimum step of the driving wheel, and users or closed - loop systems cannot flexibly select infusion modes to meet the actual needs of the body for drugs.

[0039] To solve this problem, the present invention provides a single - side - driven drug infusion device, which is provided with at least two retaining walls, can accurately control the rotation amplitude of the driving component, improve the infusion accuracy of the infusion device, and users or closed - loop systems can flexibly select different infusion modes to accurately control the body fluid level to meet the needs of the body.

[0040] Now, various exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings. It should be understood that unless otherwise specifically stated, the relative arrangements of components and steps, numerical expressions and values set forth in these embodiments should not be construed as limiting the scope of the present invention.

[0041] In addition, it should be understood that for the sake of convenience of description, the sizes of the various components shown in the drawings are not necessarily drawn in actual proportional relationships. For example, the thickness, width, length or distance of some units may be enlarged relative to other structures.

[0042] The following description of the exemplary embodiments is merely illustrative and in no sense limits the present invention and its application or use. Technologies, methods and devices known to those of ordinary skill in the relevant art may not be discussed in detail here, but when applicable, these technologies, methods and devices should be regarded as part of this specification.

[0043] It should be noted that like reference numerals and letters refer to like items in the following figures. Therefore, once an item is defined or described in one figure, it will not require further discussion in the subsequent figure descriptions.

[0044] Figure 1a 、 Figure 1b are respectively top views of a drug infusion device with single-sided drive according to two different embodiments of the present invention.

[0045] The drug infusion device with single-sided drive includes: an adhesive patch 100, a control unit 101, an infusion unit 102, and an infusion needle 103.

[0046] The control unit 101 is used to control the output of the linear driver or the reset unit force inside the infusion unit 102 to control drug infusion. The control unit 101 can also establish wireless communication with a remote device.

[0047] The infusion unit 102 includes various units for implementing the mechanical function of drug infusion, which will be described in detail below.

[0048] In the embodiment of the present invention, the control unit 101 and the infusion unit 102 are separately designed and are connected by a waterproof plug. The control unit 101 can be reused, and the infusion unit 102 can be discarded after one-time use. In other embodiments of the present invention, the infusion unit 102 and the control unit 101 are arranged inside the same housing 10 and are connected by wires, and are discarded as a whole after one-time use, as Figure 1b shown.

[0049] The adhesive patch 100 is used to paste the infusion unit 102 or the control unit 101, or both as a whole on the skin surface.

[0050] One end of the infusion needle 103 is communicated with the outlet of the drug storage unit, and the other end is sent under the skin to infuse the drug under the skin. In the embodiment of the present invention, the infusion needle 103 is arranged at one end of the infusion unit 102. In other embodiments of the present invention, the infusion needle 103 can also be arranged at other positions according to its functions or the structural characteristics of the device, such as in the middle position of the infusion device, etc., which is not specifically limited here. The infusion needle 103 is a rigid infusion needle or a flexible infusion needle, or according to different positions and different functions, the infusion needle 103 can also adopt a design combining a rigid infusion needle and a flexible infusion needle, which is not specifically limited here. Preferably, in the embodiment of the present invention, the infusion needle 103 is a rigid infusion needle.

[0051] Figure 2 is a schematic diagram of the main structure inside the infusion unit 102 according to the embodiment of the present invention.

[0052] The internal structure of the infusion unit 102 mainly includes a medicine storage unit 110, a piston 120, a screw 130, a driving wheel 140, a driving unit (not shown), a reset unit 170, and a linear driver 180. The driving unit includes a driving component 150 and a rotating shaft 160. In an embodiment of the present invention, the driving component 150 is respectively connected to the reset unit 170 and the linear driver 180 (here, the connection includes mechanical connection or electrical connection).

[0053] The medicine storage unit 110 is used to store medicines. The medicines include but are not limited to insulin, glucagon, antibiotics, nutrient solutions, analgesics, morphine, anticoagulants, gene therapy drugs, cardiovascular drugs, or chemotherapy drugs, etc.

[0054] The piston 120 is used to infuse liquid medicine into the body.

[0055] The screw 130 is respectively connected to the piston 120 and the driving wheel 140. In an embodiment of the present invention, the driving wheel 140 drives the screw 130 to advance in a threaded manner by rotation, and then pushes the piston 120 disposed in the medicine storage unit 110 to move forward, so as to achieve the purpose of infusing medicine. The screw 130 is a rigid screw or a flexible screw. When the screw 130 is a flexible screw, the screw 130 can be designed to be bent. In an embodiment of the present invention, the flexible screw is formed by movably connecting a plurality of sub-units with threads.

[0056] The circumferential surface of the driving wheel 140 is provided with teeth 141. The teeth 141 are gear teeth or ratchet teeth. Specifically, in an embodiment of the present invention, the teeth 141 are ratchet teeth. The ratchet teeth can be more easily pushed, improving the driving efficiency.

[0057] The driving component 150 includes a driving end 151 for pushing the teeth 141, and then driving the driving wheel 140 to rotate. The driving component 150 is movably connected to the rotating shaft 160.

[0058] The reset unit 170 and the linear driver 180 cooperate with each other to make the driving component 150 rotate reciprocally around the rotating shaft 160, as Figure 2 shown in the R direction, and make the driving end 151 move in the forward direction and the reset direction. When the driving component 150 makes one reciprocating rotation, the driving end 151 pushes the driving wheel 140 to advance a distance of one tooth, the driving wheel 140 drives the screw 130 to advance one step, and then pushes the piston 120 to complete one medicine infusion.

[0059] It should be noted here that the forward direction of the driving end 151 refers to the direction of pushing the teeth 141 to move. The reset direction of the driving end 151 is opposite to the forward direction. During reset, the driving end 151 only slides on the surface of the teeth 141 without applying a push.

[0060] In some embodiments of the present invention, the reset unit 170 includes elastic members such as springs, shrapnel, elastic plates, elastic rods, and elastic reset rubbers. Here, the spring includes a compression spring, a tension spring, or a torsion spring, etc., and the spring hereinafter has the same meaning as here. Specifically, in the embodiments of the present invention, the reset unit 170 is a torsion spring. The torsion spring is more conducive to driving the component 150 to rotate in the reset direction. In some embodiments of the present invention, the reset unit 170 can also be an elastic conductive member, such as a metal spring, a conductive rubber, etc. In other embodiments of the present invention, the reset unit 170 further includes an electric drive type linear driver or an electric heating type linear driver, such as a shape memory alloy. The embodiments of the present invention do not specifically limit the type, material selection, and position of the reset unit 170, as long as the condition of enabling the driving component 150 to rotate in the reset direction can be satisfied.

[0061] After being powered on, the physical form of a linear driver such as a shape memory alloy changes. The shape memory alloy undergoes a contraction deformation and outputs power. The greater the current, the greater the contraction deformation amount of the shape memory alloy, and the greater the power. Obviously, when the current is constant, the power output by the shape memory alloy is constant. Therefore, a linear driver such as a shape memory alloy can output stable and controllable power.

[0062] The linear driver 180 is an electric drive type linear driver or an electric heating type linear driver. By alternately energizing and de-energizing, the linear driver 180 outputs or stops outputting power. Specifically, in the embodiments of the present invention, the linear driver 180 is a shape memory alloy.

[0063] Figures 3a - 3c It is a top view of the structure in which the driving end 151 of different embodiments of the present invention pushes the gear 141 to move. Figures 4a - 4c It is a schematic structural diagram of the mutual cooperation between the linear driver 180 and the reset unit 170 and the driving component 150 in different embodiments of the present invention.

[0064] As Figure 3a and Figure 3b shown, the principle of the reciprocating rotation of the driving component 150 in the embodiments of the present invention is as follows: When the linear driver 180 pulls the driving component 150 with a force F P the driving component 150 rotates counterclockwise around the rotating shaft 160, and can drive the driving end 151 to push the gear 141 forward, the driving wheel 140 rotates in the forward direction, and further drives the screw 130 to move forward in the D A direction. The reset unit 170 is an elastic member and generates an increasingly strong elastic force F R . When the linear driver 180 stops providing power, the driving component 150 is under the elastic force F RUnder the action of [force], it rotates clockwise around the rotating shaft 160. At this time, the driving end 151 stops pushing the gear 141 and slides on the surface of the gear 141, and the driving wheel 140 stops rotating. The driving component 150 completes one reciprocating rotation.

[0065] As Figure 3b shown, in another embodiment of the present invention, the reset unit 170 and the linear driver 180 are both arranged on one side of the rotating shaft 160. And according to the conventional technical principle, those skilled in the art can adjust the positional relationship and the connection relationship between the reset unit 170, the driving component 150, and the linear driver 180, which are not specifically limited here as long as the above-mentioned rotation conditions can be satisfied.

[0066] As Figure 3c shown, in yet another embodiment of the present invention, the reset unit 170 includes an electric drive type linear driver or an electric heating type linear driver, such as a shape memory alloy, etc. The principle that the driving end 151 pushes the gear 141 is the same as that described above, but after the driving end 151 stops advancing, the driving component 150 cannot automatically reset, and the reset unit 170 needs to provide a reset force F B . F P is opposite to the direction of F B , and the reset unit 170 and the linear driver 180 cooperate with each other to make the driving component 150 rotate reciprocally. Obviously, those skilled in the art can adjust the direction of F P and F B as needed, as long as the conditions for making the driving component 150 rotate reciprocally can be satisfied, as Figures 4a - 4c shown.

[0067] Preferably, as Figures 3a - 3c shown, in the embodiment of the present invention, the direction of F P is parallel to the direction of F R (or F B ) and the direction of D A . Such a parallel design makes full use of the internal space and structural relationship of the infusion device, making the internal structure more compact.

[0068] In other embodiments of the present invention, the direction of F P and the direction of F R (or F B ) or the direction of D A may not be parallel either, which is not specifically limited here as long as the purpose of making the driving component 150 rotate reciprocally can be achieved.

[0069] Figure 5a And Figure 5b is a schematic structural diagram where the pulling direction of the linear driver 180 is not parallel to the advancing direction of the screw 130. Figure 5b isFigure 5a Top view of the .

[0070] Linear drive 180 pull F P The direction of the screw 130 is the same as the advancing direction D A The rotating shaft 160 and the reset unit 170 are arranged on the base 190. As mentioned above, the reciprocating rotation of the driving component 150 in the R direction can drive the driving end 151 to push the gear 141, so that the driving wheel 140 rotates in the W direction, thereby driving the screw 130 in the D direction. A The driving principle of the driving component 150 is consistent with the above.

[0071] Figures 6a - 6c They are schematic diagrams of the structure of the driving component 150 in the initial position, the half-position and the full-position respectively.

[0072] In the embodiment of the present invention, the infusion device is further provided with retaining walls 171 and 172 that can limit the forward position of the driving component 150. The retaining wall 171 is a half-distance retaining wall, and the retaining wall 172 is a full-distance retaining wall. When the driving component 150 is in the initial position, the driving component 150 does not contact the retaining wall. When the driving component 150 is in the half-distance position, the driving component 150 contacts the retaining wall 171. When the driving component 150 is in the full-distance position, the driving component 150 contacts the retaining wall 172. When the driving component 150 contacts the retaining wall 171 or 172, the potential of the contact point changes. The electrical signal generated by the potential change is transmitted to the control unit 101 through the wire. The control unit 101 determines whether the driving unit has reached the end point of the selected infusion mode. In the embodiment of the present invention, the driving wheel 140 drives the screw 130 forward one step, and the infusion unit completes the infusion of one unit of drug infusion. Then, in one reciprocating motion, when the end point of the driving unit's movement is the contact point between the driving unit and the half-distance retaining wall 171, the infusion of 1 / 2 unit of drug infusion can be achieved, and the rotation amplitude of the driving component 150 is accurately controlled to improve the accuracy of infusion, thereby meeting the requirements of users or patients for different infusion accuracies.

[0073] Specifically, when the linear driver 180 pulls the driving component 150 forward to contact the half-way retaining wall 171, a first electrical signal is triggered. The driving end 151 pushes the driving wheel 140 forward by a distance of 1 / 2 tooth, and the driving wheel 140 drives the screw 130 forward by 1 / 2 step. The first electrical signal is transmitted to the control unit 101 to determine whether the driving unit has reached the end point of the selected infusion mode. When the highest precision requirement in the selected infusion mode is 1 / 2 unit infusion volume, the control unit 101 controls the linear driver 180 to stop outputting power, and the driving unit is reset under the action of the reset unit. When the highest precision requirement in the selected infusion mode is 1 unit infusion volume, the control unit 101 controls the linear driver 180 to continue outputting power. When the linear driver 180 pulls the driving component to continue moving forward, squeezes the half-way retaining wall 171, and contacts the full-way retaining wall 172, a second electrical signal is triggered. The driving end 151 pushes the driving wheel 140 forward by another 1 / 2 tooth distance, and the driving wheel 140 drives the screw 130 forward by another 1 / 2 step. The control unit 101 controls the linear driver 180 to stop outputting power, and the driving unit is reset under the action of the reset unit.

[0074] In an embodiment of the present invention, when infusing insulin, if the unit infusion volume is 0.001U, then in one reciprocating motion, infusions of 0.0005U and 0.001U can be completed. Correspondingly, when the selected infusion mode requires 0.0015U, the infusion can be completed by controlling one full-way reciprocating motion and one half-way reciprocating motion of the driving unit. Of course, when the selected infusion mode requires 0.001U*n + 0.0005U, the infusion can be completed by controlling n full-way reciprocating motions and one half-way reciprocating motion of the driving unit.

[0075] In another embodiment of the present invention, the number of retaining walls can also be 3, namely the 1 / 3-way retaining wall, the 2 / 3-way retaining wall, and the full-way retaining wall respectively. Then, in one infusion process, an infusion of 1 / 3 unit infusion volume can be achieved, further precisely controlling the rotation amplitude of the driving component 150, improving the infusion precision, and meeting the requirements of users or patients for different infusion precisions. Similarly, the number of retaining walls can also be 4 or more (n≥4). Correspondingly, the infusion precision can be increased to 1 / n unit infusion volume. Theoretically, the larger n is, the higher the infusion precision is, and the more it can meet the requirements of different users or patients for different infusion precisions. However, due to the requirement of miniaturization of the infusion device volume, too many retaining walls will increase the volume of the infusion device and the design difficulty of the infusion device. Therefore, the number of retaining walls is preferably 2-3.

[0076] In an embodiment of the present invention, the retaining walls 171 and 172 are arranged on the same side of the driving unit. The reset unit 170 is an elastic member or an elastic conductive member. No retaining wall is arranged on the other side of the driving unit. The rotation end point of the driving member 150 on the other side is determined by the reset unit. One or two retaining walls can also be arranged on the other side of the driving unit, and the reset unit and the retaining walls jointly drive the movement end point of the driving member 150 on the other side.

[0077] In another embodiment of the present invention, the reset unit 170 is an electrically driven linear driver or an electrically heated linear driver, such as a shape memory alloy, etc. The retaining walls 171 and 172 are arranged on the same side of the driving unit. Two corresponding retaining walls are also arranged on the other side of the driving unit to limit the rotation end point of the driving member 150 on the other side. One retaining wall can also be arranged on the other side of the driving unit only. The other rotation end point of the driving member 150 on the other side is jointly controlled by the control unit 101 and the retaining wall. No retaining wall can also be arranged on the other side of the driving unit, and the rotation end point of the driving member 150 on the other side is all controlled by the control unit 101.

[0078] Similarly, in an embodiment of the present invention, when the number of retaining walls on one side of the driving unit is more than 2, the number of retaining walls arranged on the other side of the driving unit is not specifically limited herein, as long as the movement end point of the driving member 150 on the other side can be controlled.

[0079] In an embodiment of the present invention, the retaining wall is an elastic conductive member, such as a conductive spring, a conductive shrapnel, a conductive rubber or a conductive silica gel, etc. Preferably, in an embodiment of the present invention, the retaining wall is a spring pin (POGO PIN). The retaining wall 171 is arranged along the horizontal direction (the direction of the driving screw 130), and the retaining wall 172 is arranged along the vertical direction (the direction perpendicular to the bottom surface of the infusion device), which can make full use of the internal space of the infusion device and optimize the structural layout of the infusion device. The end position of the retaining wall 171 is closer to the driving unit than the end of the retaining wall 172 so as to sequentially contact the driving unit smoothly to determine the movement end point of the driving member 150 and trigger an electric signal to achieve high-precision infusion of the infusion device. In other embodiments of the present invention, the structure, material and setting method of each retaining wall are not specifically limited herein, as long as it can contact the driving unit to determine the movement end point of the driving member 150 and trigger an electric signal to achieve high-precision infusion of the infusion device.

[0080] Figure 7 It is a schematic diagram of the change in the reciprocating rotation amplitude of the driving member 150 in an embodiment of the present invention.

[0081] The principle of the driving member 150 in the embodiment of the present invention to achieve two reciprocating rotation amplitudes is as follows: The control unit 101 controls the magnitude of the power output of the linear driver 180, and in combination with the action of the reset unit 170, makes the driving member 150 reciprocate and rotate, and makes the driving end 151 advance and reset. En Indicates the position where the front end of the driving end arrives, such as E1, E2, E3, E4, E5. h n Respectively represent two different positions E n The distance between them. S n Indicates different positions of the action point S of the power of the linear actuator 180 during the reciprocating rotation, Figure 7 The midpoint arc represents the movement trajectory of S, then S1, S2, S3, S4, S5 correspond to E1, E2, E3, E4, E5 respectively. Obviously, the distances between different S n can be used to represent the rotation amplitude of the driving component 150. Specifically, in the embodiment of the present invention, h1 is the tooth pitch of the gear 141, h1 = 3h2. The linear actuator 180 makes the driving end 151 push the gear 141 to advance from E1 to the E2 position according to the instruction, the linear actuator 180 stops outputting power, and the reset unit 170 resets the driving end 151 to the E3 position and then stops resetting. The driving component 150 completes the first reciprocating rotation, and the rotation amplitude of the driving component 150 is S1 - S2 and S2 - S3. During the first reciprocating rotation, the distance that the front end of the driving end pushes the gear 141 forward is h1, the drug infusion volume is V1, and the reset distance is h3. At this time, the drug infusion volume V1 is regarded as the unit infusion volume in the first mode. When the next drive is performed, the linear actuator 180 outputs power again. During the process that the front end of the driving end advances a distance of h3, the driving end 151 slides on the surface of the gear 141, and the driving wheel 140 does not rotate, and the infusion device does not perform drug infusion. When the front end of the driving end reaches the E2 position and continues to advance a distance of h4, the front end of the driving end pushes the gear 141 to advance to the E4 position, the driving wheel 140 rotates, and the infusion device performs drug infusion. The linear actuator 180 stops power output, and the reset unit 170 resets the driving end 151 to a specific position, such as the E5 position. The driving component 150 completes the second reciprocating rotation, and the rotation amplitude of the driving component 150 is S3 - S4 and S4 - S5. During the second reciprocating rotation, the distance that the front end of the driving end advances is (h3 + h4), the distance that the driving end 151 pushes the gear 141 forward is h4, and the drug infusion volume is V2. At this time, the drug infusion volume V2 is the unit infusion volume in the second mode. Obviously, since h1 > h4 in the two modes, the driving component 150 only drives the driving wheel 140 to rotate under the rotation amplitudes S1 - S2 and S2 - S4 respectively, and the rotation amplitude S1 - S2 is greater than the rotation amplitude S2 - S4, so V1 > V2. Therefore, the infusion device in the embodiment of the present invention has two different unit infusion volumes.

[0082] By analogy, the distances between E1, E2, E3, E4, and E5 can be arbitrarily selected, such as h1 = h2, h1 = 2h2, h1 = 4h2, etc., and the infusion device then has a variety of different unit infusion volumes. Or the force application point S can also be rotated to the position of S6. Moreover, S4 and S6 are not the limit positions for driving the rotation of the driving member 150, and no specific limitation is made here.

[0083] It should be noted that, as described above, in the embodiments of the present invention, when the driving end 151 advances, the infusion device does not necessarily perform drug infusion. Only when the driving end 151 pushes the gear 141 forward does the infusion device perform drug infusion.

[0084] Each reciprocating rotation of the driving member 150 corresponds to a unit infusion volume. The driving member 150 has a variety of different rotation amplitudes, so the drug infusion device has a variety of different unit infusion volumes. Taking insulin as an example, the unit infusion volume range of the drug infusion device in the embodiments of the present invention is 0.0005U to 0.25U (here, the unit infusion volume range includes the endpoint values, that is, the unit infusion volume includes 0.0005U and 0.25U). For example, in some embodiments of the present invention, the unit infusion volume of the drug infusion device may include 0.001U, 0.0025U, 0.005U, 0.0075U, 0.01U, 0.025U, 0.05U, 0.075U, 0.1U, etc. Specifically, in the embodiments of the present invention, the unit infusion volume of the drug infusion device includes 0.005U, 0.0075U, 0.01U, 0.025U, 0.05U.

[0085] It should be noted that, in the embodiments of the present invention, the insulin concentration is 100U / ml. In other embodiments, the insulin concentration can also be 200U / ml, 400U / ml, etc., and no specific limitation is made here.

[0086] It should be noted here that when h1 = h2, the unit infusion volume of the infusion device always remains V1, and the rotation amplitude of the driving member 150 always remains between S1 - S2 and S2 - S1. At this time, the drug infusion volume is relatively stable.

[0087] The embodiments of the present invention can increase the power output frequency of the linear driver 180 or the reset unit 170, increase the reciprocating rotation frequency or the reciprocating rotation rate of the driving member 150, and thus improve the drug infusion rate of the infusion device.

[0088] Moreover, the infusion devices of other embodiments of the present invention can all change the power output frequency of the linear driver 180 or the reset unit 170 so as to have multiple infusion rates. Here, the change in the power output frequency of the linear driver 180 or the reset unit 170 can change the rate of any single movement of the driving component 150, the rate of reciprocating movement, or the frequency of reciprocating movement, etc.

[0089] Figure 8a and Figure 8b is a schematic structural diagram of the driving wheel 140 and the base 190 or the limiting component 191 according to an embodiment of the present invention. Figure 8a 、 Figure 8b is Figure 3c front view of.

[0090] When the driving end 151 slides on the surface of the tooth 141, the driving end 151 applies a certain pressure to the driving wheel 140 through contact with the tooth 141 to ensure that the driving wheel 140 does not rotate. However, obviously, due to the structural characteristics of the tooth 141 and the circumference of the driving wheel 140, at different positions, the pressure of the driving end 151 on the driving wheel 140 is not equal. Therefore, when the driving end 151 slides on the surface of the tooth 141 (including the reset movement or the forward sliding), the driving wheel 140 has the possibility of rotating forward or in reverse, which affects the accuracy of the drug infusion volume and poses a safety hazard. Therefore, the embodiment of the present invention further increases the friction between the driving wheel 140 and its adjacent structure, and further reduces the probability of the above problems.

[0091] As Figure 8a shown, the driving wheel 140 is movably assembled on the base 190, and the two are in frictional cooperation with each other. Here, the frictional cooperation means that there is a certain preset friction force between two mutually moving structures, and the meaning of the frictional cooperation below is the same as that here. The embodiment of the present invention increases the friction force of the relative movement between the driving wheel 140 and the base 190 at position A (as shown by the dotted line frame) to ensure that the driving wheel 140 stops rotating when the driving end 151 slides on the surface of the tooth 141.

[0092] As Figure 8b shown, in another embodiment of the present invention, the infusion device further includes a limiting component 191. The limiting component 191 is movably assembled on the base 190 to limit the position of the driving wheel 140. The limiting component 191 is in frictional cooperation with the driving wheel 140, and the position of the frictional cooperation is at position B or position C (as shown by the dotted line frame). Similarly, the embodiment of the present invention increases the friction force received by the driving wheel 140 during rotation through the limiting component 191 to ensure that the driving wheel 140 stops rotating when the driving end 151 slides on the surface of the tooth 141. At the same time, the limiting component 191 can make full use of the internal structure of the infusion device to be in frictional cooperation with the driving wheel 140 at different positions.

[0093] The embodiments of the present invention do not limit the position of the above-mentioned frictional fit, as long as the condition of increasing the frictional force received by the driving wheel 140 during rotation can be satisfied. For example, it can also act on two sides of the driving wheel 140 simultaneously. The embodiments of the present invention also do not limit the material of the limiting member 191. For example, the limiting member 191 includes an elastic member, a plastic member, a metal member, etc.

[0094] In other embodiments of the present invention, the above-mentioned frictional fit may not be provided, but instead, the pressure of the driving end 151 on the tooth 141 is increased, thereby increasing the maximum static frictional force of the driving wheel 140 to ensure that the driving wheel 140 does not rotate when the driving end 151 slides on the surface of the tooth 141.

[0095] Figure 9 、 Figure 10 FIG. is a schematic structural diagram of a driving unit including two driving components according to different embodiments of the present invention.

[0096] As Figure 9 shown, the driving component 250a reciprocally rotates around the rotating shaft 260 in the R direction under the action of the linear driver 280a and the reset unit 270a. Similarly, the driving component 250b reciprocally rotates around the rotating shaft 260 in the R direction under the action of the linear driver 280b and the reset unit 270b. In the embodiments of the present invention, the rotations of the two driving components do not interfere with each other, and both the driving component 250a and the driving component 250b can independently implement the driving method described above.

[0097] Preferably, in the embodiments of the present invention, the driving components 250a and 250b rotate non-synchronously. That is, when the driving end 251a of the driving component 250a pushes the tooth 241 to move, the driving end 251b of the driving component 250b slides on the surface of the tooth 241. When the driving end 251b slides to a certain position, the control unit controls the linear driver 280a to stop outputting power to the driving component 250a, and instead controls the linear driver 280b to output power to the driving component 250b. At this time, the driving component 250a rotates in the clockwise direction under the action of the reset unit 270a, the driving end 251a slides on the tooth surface, while the driving end 251b pushes the tooth 241. Push alternately in sequence, and then the driving components 250a and 250b complete the alternate pushing of the driving wheel 240.

[0098] In the embodiments of the present invention, the pulling forces F of the linear drivers 280a and 280b P 、the elastic forces F of the reset units 270a and 270b R and the advancing direction D of the screw 230 A are as shown in the figure. As described above, the direction of the pulling force F P is parallel to the advancing direction D of the screw 230 A .

[0099] In an embodiment of the present invention, the types of the reset units 270a and 270b may refer to the above, and will not be elaborated here.

[0100] As Figure 10 shown, the driving ends 351a and 351b respectively and alternately push the teeth 341, and the power outputs of the linear drivers 380a and 380b are both controlled by the control unit.

[0101] It should be noted that, in an embodiment of the present invention, the pulling force F P ' of the linear driver 380a and the pulling force F P " of the linear driver 380b are in opposite directions. Obviously, the reset force F R ' of the reset unit 370a and the reset force F R " of the reset unit 370b are also in opposite directions.

[0102] Similarly, in an embodiment of the present invention, the driving components 350a and 350b rotate non-synchronously. That is, when the driving end 351a of the driving component 350a pushes the tooth 341 forward, the driving end 351b of the driving component 350b slides on the surface of the tooth 341. When the driving end 351b slides to a certain position, the control unit controls the linear driver 380a to stop outputting power to the driving component 350a, and instead controls the linear driver 380b to output power to the driving component 350b. The driving component 350a rotates in the clockwise direction under the action of the reset unit 370a, the driving end 351a slides on the surface of the tooth 341, and the driving end 351b pushes the tooth 341. By alternately pushing in this way, the driving components 350a and 350b complete the alternate pushing of the driving wheel 340.

[0103] Similarly, the driving components 350a and 350b can each independently implement the driving method described above. The types of the reset units 370a and 370b may refer to the above, and will not be elaborated here.

[0104] It should be noted that, in other embodiments of the present invention, the driving unit may further include more driving components, each driving component may further include more driving ends, or the infusion device may include more driving wheels, and different driving components respectively push the corresponding driving wheels to rotate.

[0105] Figure 11a And Figure 11b is a schematic structural diagram of two driving ends 451a and 451b of a driving component 450 in an embodiment of the present invention respectively cooperating with two driving wheels 440a and 440b. Figure 11b Is Figure 11a a right view of a partial tooth structure of the driving wheels 440a and 440b.

[0106] As Figure 11a and Figure 11b shown, in the embodiment of the present invention, the driving component 450 includes two driving ends 451a and 451b arranged left and right, and two driving wheels 440a and 440b arranged left and right are fixedly connected (that is, the two driving wheels can move forward synchronously). The driving ends 451a and 451b can respectively push the driving wheels 440a and 440b to rotate. The rotating shaft 460 is arranged on the same side of the two driving wheels 440a and 440b. The linear driver 480 and the reset unit 470 in the embodiment of the present invention are both shape memory alloys. Either the driving end 451a or 451b can push the tooth 441a or 441b forward. Its working principle and operation mode are the same as those described above, and will not be elaborated here.

[0107] In addition to each driving end 451a or 451b individually implementing the pushing, in the embodiment of the present invention, the distance between the front ends of the driving ends 451a and 451b can also be adjusted, or the degree of staggering of the teeth 441a and 441b can be adjusted so that the two driving ends 451a and 451b cooperate with each other. Preferably, in the embodiment of the present invention, the teeth 441a and 441b are staggeredly arranged, and the degree of staggering is t, as Figure 11a and Figure 11b shown.

[0108] Obviously, in the embodiment of the present invention, the two driving ends 451a and 451b move reciprocally synchronously. As Figure 11a shown, after the previous forward movement ends, the driving component 450 starts to rotate for resetting. The driving end 451a reaches the driving position earlier than the driving end 451b. The driving component 450 can use the driving end 451a to start the next forward movement. Or the driving component 450 can continue to rotate for resetting until the driving end 451b reaches the next driving position to start the next forward movement. Of course, the driving component 450 can also continue to rotate for resetting a greater distance, as described above. Here, the driving position refers to the position where the driving end can push the tooth forward, such as Figure 7 the positions E1 and E2 in , and the meaning of the driving position in the following text is the same as here.

[0109] Therefore, by controlling the rotation amplitude of the driving component 450, either the driving end 451a or 451b can individually push the corresponding tooth 441a or 441b forward, or the driving ends 451a and 451b can alternately push the teeth forward, so that the infusion device has multiple unit infusion amounts.

[0110] Figure 12a and Figure 12b are schematic structural diagrams of another embodiment of the present invention in which the driving component 550 includes two driving ends 551a and 551b arranged up and down, and the driving ends 551a and 551b cooperate with the same driving wheel 540. Figure 12b isFigure 12a Three-dimensional structure diagram of the middle driving component 550.

[0111] As Figure 12a and Figure 12b shown, the driving component 550 includes two driving ends 551a and 551b arranged up and down, and both cooperate with the same driving wheel 540. The driving ends 551a and 551b move reciprocally synchronously. The front ends of the driving ends 551a and 551b are not flush. For example, the two are separated by a certain distance m, so that the two cannot simultaneously push the tooth 541 forward, as Figure 12a shown. When the driving end 551b finishes the previous forward movement, the driving component 550 rotates for reset. The driving end 551a reaches the next driving position earlier than the driving end 551b. The driving component 550 can use the driving end 551a to push the tooth 541 forward and start the next forward movement. Or the driving component 550 continues to rotate for reset until the driving end 551b reaches the next driving position and starts the next forward movement. Of course, the driving component 550 can also continue to rotate for reset to make the driving ends 551a and 551b reset by a greater distance, as described above.

[0112] Therefore, by controlling the power output of the linear driver 580 or the reset unit 570, the driving component 550 has different rotation amplitudes. The driving end 551a or 551b can push the tooth 541 forward alone, or the two alternately push the tooth 541 forward, so that the infusion device has a variety of different unit infusion volumes.

[0113] In other embodiments of the present invention, the driving component may further include more driving ends, such as 3, 4 or more, which are not specifically limited herein.

[0114] In summary, the present invention discloses a drug infusion device with unilateral drive, having at least 2 retaining walls, which can accurately control the rotation amplitude of the driving unit, so that the minimum infusion volume is at least 1 / 2 of the unit infusion volume, improving the infusion accuracy of the infusion device. Users or closed-loop systems can flexibly select according to the actual needs of the body to achieve the purpose of accurately controlling the body fluid level, meeting the needs of users and improving the user experience.

[0115] Although some specific embodiments of the present invention have been described in detail by way of examples, those skilled in the art should understand that the above examples are only for illustration and not for limiting the scope of the present invention. Those skilled in the art should understand that the above embodiments can be modified without departing from the scope and spirit of the present invention. The scope of the present invention is defined by the appended claims.

Claims

1. A drug infusion device with unilateral drive, characterized in that, Comprising: A medicine storage unit, a piston and a screw rod, wherein the piston is arranged in the medicine storage unit and the piston is connected to the screw rod; A driving unit, the driving unit includes at least one rotating shaft and at least one driving component, the driving component includes at least one driving end, and the driving component rotates around the rotating shaft to make the driving end advance or reset; At least one driving wheel provided with teeth, and the advancing driving end pushes the teeth to make the driving wheel rotate, thereby driving the screw rod to advance; A linear driver and a reset unit respectively connected to the driving component, and the linear driver and the reset unit respectively apply acting forces to the driving component to make the driving end advance and reset respectively; And At least two retaining walls, the retaining walls are arranged at different positions on the same side of the driving unit and are used to define the advancing position of the driving unit. Among them, different retaining walls on the same side of the driving unit correspond to different movement amplitudes of the driving component and correspond to different infusion precisions of the medicine infusion device.

2. The single-sided drive drug infusion device according to claim 1, wherein, The retaining wall is an elastic conductive member.

3. The single-sided drive drug infusion device according to claim 2, characterized in that, The elastic conductive member is a conductive spring, a conductive shrapnel, a conductive rubber or a conductive silica gel.

4. The single-sided drive drug infusion device according to claim 1, characterized in that, The linear driver includes an electrically driven linear driver or an electrically heated linear driver.

5. The single-sided drive drug infusion device according to claim 1, characterized in that The reset unit includes an electrically driven linear driver or an electrically heated linear driver.

6. The single-sided drive drug infusion device according to claim 5, characterized in that, It further includes at least one retaining wall arranged on the other side of the driving unit.

7. The single-sided drive drug infusion device according to claim 6, wherein It further includes a control unit, which together with at least one retaining wall arranged on the other side of the driving unit controls the movement end point of the driving component.

8. The single-sided drive drug infusion device according to claim 1, characterized in that The reset unit is an elastic member, and the elastic member includes at least one or more of a spring, a shrapnel, an elastic plate, an elastic rod or an elastic reset rubber.

9. The single-sided drive drug infusion device according to claim 8, characterized in that, The reset unit is an elastic conductive member.

10. The single-sided drive drug infusion device according to claim 9, characterized in that, The elastic conductive member is a metal spring or a conductive rubber.

11. The single-sided drive drug infusion device according to claim 1, characterized in that, The driving component has a variety of different operating modes, so that the infusion device has a variety of different unit infusion amounts or infusion rates.

12. The single-sided drive drug infusion device according to claim 11, characterized in that, The operating modes of the driving component include the amplitude of reciprocating motion, the frequency of reciprocating motion or the motion rate. The variety of different operating modes of the driving component include reciprocating motions with different amplitudes or frequencies, or include different motion rates.

13. The single-sided drive drug infusion device according to claim 1, wherein It further includes a base, the driving wheel is movably assembled on the base, and the base is in frictional cooperation with the driving wheel. When the driving end slides on the tooth surface of the driving wheel, the driving wheel stops rotating.

14. The single-sided drive drug infusion device according to claim 13, characterized in that, It further includes a limiting component, the limiting component is movably assembled on the base to limit the position of the driving wheel, and the limiting component is in frictional cooperation with the driving wheel. When the driving end slides on the tooth surface of the driving wheel, the driving wheel stops rotating.

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