Temperature-controllable low-temperature biological 3D printer and nozzle device

Abstract

The present application relates to the field of 3D printer, especially to a controllable temperature low-temperature biological 3D printer and nozzle device, which comprises a base, a mounting frame, a horizontal moving module one, a vertical moving module, a horizontal moving module two, a printing platform, a printing nozzle and a control system; the printing platform comprises a mounting plate one, a support seat, an elastic piece one, a mounting box, a temperature control assembly one and a temperature control assembly two; the mounting plate one is connected with the moving end of the horizontal moving module one; the mounting box is connected with the upper end of the mounting plate one through the elastic piece one; the temperature control assembly one and the temperature control assembly two are both arranged on the mounting box. The temperature control assembly one and the temperature control assembly two are arranged to cooperate, to control the temperature of the product from the upper and lower parts respectively, the temperature control position is comprehensive, and the temperature control mode is various. The nozzle with the temperature control pipe is arranged to control the temperature of the nozzle from the inside, improving the efficiency of temperature control. The temperature control assembly three is arranged to realize the quantitative replacement of refrigerant, ensuring the stability and persistence of refrigeration effect.

Description

Technical Field

[0001] This invention relates to the field of 3D printers, and more particularly to a temperature-controlled low-temperature biological 3D printer and a nozzle device. Background Technology

[0002] Cryogenic bioprinting uses a refrigerant to rapidly cool hydrogel ink before extruding it from the 3D printer. Because of the freezing process, the hydrogel cannot be used for functional purposes, but once thawed, the printed gel is as soft as human tissue and strong enough to support itself. This is a significant breakthrough that could be used to create biological structures that regenerate tissue and replicate organs. The printed structures can mimic the characteristics of organs such as the brain and lungs. Therefore, maintaining a low-temperature environment during the printing process is crucial to this technology.

[0003] However, existing printers generally only cool the printing platform, resulting in incomplete temperature control, inability to adjust the temperature control position, and a single temperature control method, which reduces the efficiency of temperature control. Summary of the Invention

[0004] To address the problems existing in the background technology, this invention proposes a temperature-controlled low-temperature biological 3D printer and its nozzle device. The invention employs two temperature control components (component 1 and component 2) to control the product temperature from both the top and bottom, providing comprehensive temperature control and diverse control methods. A nozzle with a temperature control tube is incorporated for internal temperature control, improving efficiency. A third temperature control component enables precise refrigerant replacement, ensuring stable and sustained cooling performance.

[0005] This invention proposes a temperature-controlled low-temperature biological 3D printer, comprising a base, a mounting frame, a horizontal moving module one, a vertical moving module, a horizontal moving module two, a printing platform, a printing nozzle, and a control system. The printing platform is slidably mounted on the base along the Z-direction via the horizontal moving module one. The mounting frame is mounted on the base from both sides of the printing platform. The vertical moving module and the horizontal moving module two cooperate with each other and are mounted on the mounting frame. The printing nozzle is mounted on the horizontal moving module two and moves in the X and Y directions, while cooperating with the printing platform below. The printing platform includes a mounting plate one, a support base, an elastic element one, a mounting box, a temperature control component one, and a temperature control component two. The mounting plate one is connected to the moving end of the horizontal moving module one. The mounting box is connected to the upper end of the mounting plate one via the elastic element one. Both the temperature control component one and the temperature control component two are mounted on the mounting box.

[0006] The temperature control component includes a blower, a temperature control panel, a temperature control plate, cooling elements, a bracket, an air guide frame, and an air outlet duct. The temperature control panel is located at the top of the mounting box, with an open top and an air outlet valve at the bottom. The temperature control plate is located at the open end of the temperature control panel. The bracket is located inside the temperature control panel. Multiple sets of cooling elements are arranged on the bracket, with the cooling end contacting the temperature control panel and the heating end contacting the air guide frame. The air guide frame is located at the bottom of the temperature control panel. One end of the air outlet duct is connected to the blower, and the other end extends into the air guide frame and connects to the air outlet valve.

[0007] Temperature control component two includes a drive unit, a lead screw, a lifting column, a temperature control frame, an exhaust pipe, and a refrigeration unit; the lead screw is located at the four corners of the mounting box and rotates synchronously through the drive unit; the lifting column corresponds to the lead screw one by one and is threaded; the temperature control frame is located on the lifting column and fits around the temperature control panel; the exhaust pipe connects the refrigeration unit and the temperature control frame.

[0008] Preferably, the cooling elements are arranged radially around the axis of the temperature control plate and are engaged with the bracket.

[0009] Preferably, the air outlet duct is coaxial with the temperature control panel; the air guide frame is in a planar spiral shape and is fitted around the air outlet duct.

[0010] Preferably, the mounting box is equipped with a positioning seat; the positioning seat is equipped with a connecting air outlet valve and an air inlet pipe; the air outlet valve is connected to the air outlet pipe; the air inlet pipe is connected to the air blower.

[0011] Preferably, the driving components include a motor, gear 1, gear 2, a drive shaft, gear 3, and gear 4; the lower end of the lead screw extends into the mounting box and corresponds one-to-one with gear 1, and is keyed; gear 1 and gear 2 correspond one-to-one and are meshed; gear 4, driven by motor 1, is rotatably positioned at the center of the mounting box; four sets of gear 3 are arranged along the tooth surface of gear 4, meshing with it sequentially, and their positions correspond one-to-one with gear 2; the two ends of the drive shaft are keyed to the corresponding gear 2 and gear 3 respectively.

[0012] Preferably, a second vent valve is provided on the side of the temperature control frame facing the temperature control plate.

[0013] Preferably, the temperature control plate is made of a heat-conducting and cold-conducting material, and a temperature sensor is installed on the temperature control plate.

[0014] This invention provides a temperature-controlled low-temperature biological 3D printer nozzle device, including a second mounting plate, a third temperature control component, and a nozzle; the second mounting plate is mounted on the moving end of a second horizontal moving module; the nozzle is mounted on the second mounting plate, and has an internal discharge chamber and external feed pipe, refrigerant outlet pipe, and refrigerant inlet pipe; the discharge chamber is connected to the feed pipe and has an internal discharge component and a second temperature sensor, and a spiral temperature control pipe is installed inside the discharge chamber wall; the upper end of the temperature control pipe is connected to the first refrigerant inlet pipe, and the lower end is connected to the refrigerant outlet pipe; the third temperature control component is mounted on the second mounting plate.

[0015] Preferably, the temperature control component three includes a refrigerant inlet pipe two, a buffer box, a piston plate, a piston rod, a moving frame, an eccentric wheel, a motor two, and an elastic element two; the buffer box is mounted on the mounting plate two; the piston plate is slidably mounted inside the buffer box in a vertical direction; the lower end of the piston rod extends into the buffer box and connects to the piston plate, and the upper end connects to the moving frame; the eccentric wheel, driven by the motor two, is rotatably mounted above the buffer box, and its edge is always slidably connected to the moving frame; the elastic element two is located between the buffer box and the moving frame; the refrigerant inlet pipe two and the refrigerant inlet pipe one are respectively connected to the chamber below the piston plate, and the refrigerant inlet pipe two and the refrigerant inlet pipe one are respectively equipped with one-way valves with opposite flow control directions; the refrigerant inlet pipe two is also connected to an external refrigerant storage tank.

[0016] Preferably, the nozzle is covered with an insulation sleeve; the inner wall of the insulation sleeve is lined with absorbent cotton.

[0017] Compared with the prior art, the present invention has the following beneficial technical effects:

[0018] This invention employs two temperature control components, Component 1 and Component 2, to control the product temperature from both the top and bottom. This comprehensive temperature control, utilizing both refrigeration elements and air cooling, provides diverse temperature control methods and ensures effective temperature control for the printer. A printhead with a temperature control tube controls the printhead temperature from within, improving efficiency. A third temperature control component uses a piston plate to adjust the pressure within the buffer tank, achieving precise refrigerant replacement and ensuring stable and sustained cooling performance. Attached Figure Description

[0019] Figure 1 This is a first-view diagram of an embodiment of the present invention;

[0020] Figure 2 This is a second perspective view of one embodiment of the present invention;

[0021] Figure 3 This is a schematic diagram of the printing platform in one embodiment of the present invention;

[0022] Figure 4 This is a disassembly diagram of the printing platform in one embodiment of the present invention;

[0023] Figure 5 This is an exploded view of control component one in one embodiment of the present invention;

[0024] Figure 6 This is a schematic diagram of the structure of the driving component in one embodiment of the present invention;

[0025] Figure 7 This is a first-view view of the nozzle device in one embodiment of the present invention;

[0026] Figure 8 This is a second perspective view of the nozzle device in one embodiment of the present invention;

[0027] Figure 9 for Figure 8 A sectional view;

[0028] Figure 10 for Figure 9 Enlarged partial cross-sectional view of the central adjustment component;

[0029] Figure 11 for Figure 9 Enlarged cross-sectional view of the central nozzle.

[0030] Attached reference numerals: 1. Base; 2. Mounting bracket; 3. Horizontal moving module one; 4. Vertical moving module; 5. Horizontal moving module two; 6. Printing platform; 7. Printing nozzle; 8. Mounting plate one; 9. Support base; 10. Elastic element one; 11. Mounting box; 12. Temperature control component one; 13. Temperature control component two; 14. Lead screw; 15. Lifting column; 16. Temperature control frame; 17. Air outlet pipe; 18. Refrigeration unit; 19. Air outlet valve one; 20. Fan; 21. Temperature control panel; 22. Temperature control plate; 23. Refrigeration element; 24. Bracket; 25. Air guide frame; 26. Air outlet pipe; 7. Outlet valve 1; 28. Gear 1; 29. ​​Gear 2; 30. Drive shaft; 31. Gear 3; 32. Gear 4; 33. Positioning seat; 34. Inlet pipe; 35. Mounting plate 2; 36. Temperature control component 3; 37. Nozzle; 38. Feed pipe; 39. Refrigerant outlet pipe; 40. Refrigerant inlet pipe 1; 41. Refrigerant inlet pipe 2; 42. Buffer box; 43. Piston plate; 44. Piston rod; 45. Moving frame; 46. Eccentric wheel; 47. Motor 2; 48. Temperature control pipe; 49. Insulation sleeve; 50. Absorbent cotton; 51. Discharge component; 52. Elastic component 2. Detailed Implementation

[0031] Example 1

[0032] like Figure 1-3As shown, the present invention proposes a temperature-controlled low-temperature biological 3D printer, comprising a base 1, a mounting frame 2, a horizontal moving module 3, a vertical moving module 4, a second horizontal moving module 5, a printing platform 6, a printing nozzle 7, and a control system. The printing platform 6 is driven by the first horizontal moving module 3 and is slidably mounted on the base 1 along the Z direction. The mounting frame 2 is mounted on the base 1 from both sides of the printing platform 6. The vertical moving module 4 and the second horizontal moving module 5 cooperate with each other and are mounted on the mounting frame 2. The printing nozzle 7 is mounted on the second horizontal moving module 5 and moves in the X and Y directions, while cooperating with the printing platform 6 below. The printing platform 6 includes a first mounting plate 8, a support base 9, an elastic element 10, a mounting box 11, a first temperature control component 12, and a second temperature control component 13. The first mounting plate 8 is connected to the moving end of the first horizontal moving module 3. The mounting box 11 is connected to the upper end of the first mounting plate 8 through the first elastic element 10. The first temperature control component 12 and the second temperature control component 13 are both mounted on the mounting box 11.

[0033] like Figure 5 As shown, the temperature control component 12 includes a blower 20, a temperature control plate 21, a temperature control board 22, cooling elements 23, a bracket 24, an air guide frame 25, and an air outlet pipe 26. The temperature control plate 21 is located on the upper end of the mounting box 11, with an open upper end and an air outlet valve 27 at the bottom. The temperature control board 22 is located on the open end of the temperature control plate 21 and is made of a heat-conducting and cooling material. A temperature sensor is located on the temperature control board 22. The bracket 24 is located inside the temperature control plate 21. Multiple sets of cooling elements 23 are arranged on the bracket 24, with the cooling end contacting the temperature control plate 21 and the heating end contacting the air guide frame 25. The air guide frame 25 is located at the bottom of the temperature control plate 21. One end of the air outlet pipe 26 is connected to the blower 20, and the other end extends into the air guide frame 25 and is connected to the air outlet valve 27.

[0034] like Figure 4 As shown, the second temperature control component 13 includes a drive unit, a lead screw 14, a lifting column 15, a temperature control frame 16, an exhaust pipe 17, and a refrigerator 18. The lead screw 14 is located at the four corners of the mounting box 11 and rotates synchronously through the drive unit. The lifting column 15 corresponds to the lead screw 14 one-to-one and is threaded together. The temperature control frame 16 is located on the lifting column 15 and is fitted around the temperature control plate 21. An exhaust valve 2 is provided on the side of the temperature control frame 16 facing the temperature control plate 22. The exhaust pipe 17 connects the refrigerator 18 and the temperature control frame 16.

[0035] The working principle of this embodiment is as follows: During 3D printing, the horizontal moving module 1 (3), the vertical moving module 4, and the horizontal moving module 2 (5) work together to achieve omnidirectional and multi-angle printing. The printed product is placed on the temperature control plate 22 of the printing platform 6. A low-temperature environment for the product needs to be maintained during the printing process. Temperature control components 1 (12) and 2 (13) work together to control the temperature throughout the process. Specifically, the cooling element 23 provides cooling, and the temperature control plate 22 monitors the product temperature while simultaneously conducting heat and cold to maintain the product temperature. The exhaust fan 20 delivers air to the air guide frame 25 through the exhaust pipe 26. The air moves along the air guide frame 25, carrying away the heat from the hot end of the cooling element 23. The hot air flows out from the exhaust valve 27, ensuring effective temperature control at the bottom of the product. Simultaneously, temperature control component 2 (13) is driven by a drive component, causing the lifting column 15 to move up and down along the lead screw 14. The temperature control frame 16 moves synchronously, simultaneously ejecting the cold air prepared by the cooling unit 18 to control the temperature of the upper part of the product. The present invention sets up temperature control component 12 and temperature control component 2 13 to work together to control the temperature of the product from the upper and lower parts respectively. The temperature control position is comprehensive and the temperature control method is diverse, which ensures the temperature control effect of the printer.

[0036] Example 2

[0037] like Figure 1-3 As shown, the present invention proposes a temperature-controlled low-temperature biological 3D printer, comprising a base 1, a mounting frame 2, a horizontal moving module 3, a vertical moving module 4, a second horizontal moving module 5, a printing platform 6, a printing nozzle 7, and a control system. The printing platform 6 is driven by the first horizontal moving module 3 and is slidably mounted on the base 1 along the Z direction. The mounting frame 2 is mounted on the base 1 from both sides of the printing platform 6. The vertical moving module 4 and the second horizontal moving module 5 cooperate with each other and are mounted on the mounting frame 2. The printing nozzle 7 is mounted on the second horizontal moving module 5 and moves in the X and Y directions, while cooperating with the printing platform 6 below. The printing platform 6 includes a first mounting plate 8, a support base 9, an elastic element 10, a mounting box 11, a first temperature control component 12, and a second temperature control component 13. The first mounting plate 8 is connected to the moving end of the first horizontal moving module 3. The mounting box 11 is connected to the upper end of the first mounting plate 8 through the first elastic element 10. The first temperature control component 12 and the second temperature control component 13 are both mounted on the mounting box 11.

[0038] like Figure 5As shown, the temperature control component 12 includes a blower 20, a temperature control plate 21, a temperature control board 22, cooling elements 23, a bracket 24, an air guide frame 25, and an air outlet pipe 26. The temperature control plate 21 is located on the upper end of the mounting box 11, with an open upper end and an air outlet valve 27 at the bottom. The temperature control board 22 is located on the open end of the temperature control plate 21 and is made of a heat-conducting and cooling material. A temperature sensor is located on the temperature control board 22. The bracket 24 is located inside the temperature control plate 21. Multiple sets of cooling elements 23 are arranged on the bracket 24, with the cooling end contacting the temperature control plate 21 and the heating end contacting the air guide frame 25. The air guide frame 25 is located at the bottom of the temperature control plate 21. One end of the air outlet pipe 26 is connected to the blower 20, and the other end extends into the air guide frame 25 and is connected to the air outlet valve 27.

[0039] like Figure 4 As shown, the second temperature control component 13 includes a drive unit, a lead screw 14, a lifting column 15, a temperature control frame 16, an exhaust pipe 17, and a refrigerator 18. The lead screw 14 is located at the four corners of the mounting box 11 and rotates synchronously through the drive unit. The lifting column 15 corresponds to the lead screw 14 one-to-one and is threaded together. The temperature control frame 16 is located on the lifting column 15 and is fitted around the temperature control plate 21. An exhaust valve 2 is provided on the side of the temperature control frame 16 facing the temperature control plate 22. The exhaust pipe 17 connects the refrigerator 18 and the temperature control frame 16.

[0040] like Figure 5-6 As shown, the cooling element 23 is arranged radially around the axis of the temperature control plate 21 and is engaged with the bracket 24. The air outlet duct 26 is coaxial with the temperature control plate 21; the air guide frame 25 is in a planar spiral shape and fits around the air outlet duct 26. The mounting box 11 is equipped with a positioning seat 33; the positioning seat 33 is equipped with a connecting air outlet valve 19 and an air inlet pipe 34; the air outlet valve 19 is connected to the air outlet duct 26; the air inlet pipe 34 is connected to the blower 20.

[0041] In this embodiment, the radial cooling plates 23 ensure uniform and dispersed cooling by the temperature control plate 22. The planar spiral air guide 25 makes the airflow smoother, reduces airflow loss, and effectively removes heat.

[0042] Example 3

[0043] like Figure 1-3As shown, the present invention proposes a temperature-controlled low-temperature biological 3D printer, comprising a base 1, a mounting frame 2, a horizontal moving module 3, a vertical moving module 4, a second horizontal moving module 5, a printing platform 6, a printing nozzle 7, and a control system. The printing platform 6 is driven by the first horizontal moving module 3 and is slidably mounted on the base 1 along the Z direction. The mounting frame 2 is mounted on the base 1 from both sides of the printing platform 6. The vertical moving module 4 and the second horizontal moving module 5 cooperate with each other and are mounted on the mounting frame 2. The printing nozzle 7 is mounted on the second horizontal moving module 5 and moves in the X and Y directions, while cooperating with the printing platform 6 below. The printing platform 6 includes a first mounting plate 8, a support base 9, an elastic element 10, a mounting box 11, a first temperature control component 12, and a second temperature control component 13. The first mounting plate 8 is connected to the moving end of the first horizontal moving module 3. The mounting box 11 is connected to the upper end of the first mounting plate 8 through the first elastic element 10. The first temperature control component 12 and the second temperature control component 13 are both mounted on the mounting box 11.

[0044] like Figure 5 As shown, the temperature control component 12 includes a blower 20, a temperature control plate 21, a temperature control board 22, cooling elements 23, a bracket 24, an air guide frame 25, and an air outlet pipe 26. The temperature control plate 21 is located on the upper end of the mounting box 11, with an open upper end and an air outlet valve 27 at the bottom. The temperature control board 22 is located on the open end of the temperature control plate 21 and is made of a heat-conducting and cooling material. A temperature sensor is located on the temperature control board 22. The bracket 24 is located inside the temperature control plate 21. Multiple sets of cooling elements 23 are arranged on the bracket 24, with the cooling end contacting the temperature control plate 21 and the heating end contacting the air guide frame 25. The air guide frame 25 is located at the bottom of the temperature control plate 21. One end of the air outlet pipe 26 is connected to the blower 20, and the other end extends into the air guide frame 25 and is connected to the air outlet valve 27.

[0045] like Figure 4 As shown, the second temperature control component 13 includes a drive unit, a lead screw 14, a lifting column 15, a temperature control frame 16, an exhaust pipe 17, and a refrigerator 18. The lead screw 14 is located at the four corners of the mounting box 11 and rotates synchronously through the drive unit. The lifting column 15 corresponds to the lead screw 14 one-to-one and is threaded together. The temperature control frame 16 is located on the lifting column 15 and is fitted around the temperature control plate 21. An exhaust valve 2 is provided on the side of the temperature control frame 16 facing the temperature control plate 22. The exhaust pipe 17 connects the refrigerator 18 and the temperature control frame 16.

[0046] like Figure 6As shown, the driving components include a motor, gear 28, gear 29, a drive shaft 30, gear 31, and gear 4 32; the lower end of the lead screw 14 extends into the mounting box 11 and corresponds one-to-one with gear 28, and is keyed; gear 28 and gear 29 correspond one-to-one and are meshed; gear 4 32, driven by motor 1, is rotatably positioned at the center of the mounting box 11; four sets of gear 31 are arranged along the tooth surface of gear 4 32, meshing with it in sequence, and their positions correspond one-to-one with gear 29; the two ends of the drive shaft 30 are keyed to the corresponding gear 29 and gear 31.

[0047] In this embodiment, the drive unit operates by being driven by motor one, with gear four 32, gear three 31, gear two 29 and gear one 28 transmitting power in sequence, ultimately achieving synchronous rotation of the four sets of lead screws 14. The lifting column 15 moves up and down with high consistency, the temperature control position is accurate, and it is energy-efficient.

[0048] Example 4

[0049] This invention also provides a temperature-controlled low-temperature biological 3D printer nozzle device, including a second mounting plate 35, a third temperature control component 36, and a nozzle 37; the second mounting plate 35 is mounted on the moving end of a second horizontal moving module 5; the nozzle 37 is mounted on the second mounting plate 35, and has an internal discharge chamber, an external feed pipe 38, a refrigerant outlet pipe 39, and a first refrigerant inflow pipe 40, and is covered with an insulation sleeve 49; absorbent cotton 50 is provided on the inner wall of the insulation sleeve 49. The discharge chamber is connected to the feed pipe 38, and has an internal discharge component 51 and a second temperature sensor, and a spiral temperature control pipe 48 is provided inside the chamber wall; the upper end of the temperature control pipe 48 is connected to the first refrigerant inflow pipe 40, and the lower end is connected to the refrigerant outlet pipe 39; the third temperature control component 36 is mounted on the second mounting plate 35.

[0050] Temperature control component 36 includes refrigerant inlet pipe 2 41, buffer tank 42, piston plate 43, piston rod 44, moving frame 45, eccentric wheel 46, motor 2 47, and elastic element 2 52. Buffer tank 42 is mounted on mounting plate 2 35. Piston plate 43 is slidably mounted inside buffer tank 42 in a vertical direction. The lower end of piston rod 44 extends into buffer tank 42 and connects to piston plate 43, while the upper end connects to moving frame 45. Eccentric wheel 46, driven by motor 2 47, is rotatably mounted above buffer tank 42, with its edge always slidably connected to moving frame 45. Elastic element 2 52 is located between buffer tank 42 and moving frame 45. Refrigerant inlet pipe 2 41 and refrigerant inlet pipe 1 40 are respectively connected to the chamber below piston plate 43, and one-way valves with opposite flow control directions are respectively installed on refrigerant inlet pipe 2 41 and refrigerant inlet pipe 1 40. Refrigerant inlet pipe 2 41 is also connected to an external refrigerant storage tank.

[0051] The working principle of this embodiment is as follows: When the nozzle 37 is working, the temperature sensor 2 monitors the temperature of the liquid in the discharge bin. The temperature control tube 48 contains refrigerant (such as liquid carbon dioxide) to control the temperature of the liquid. The insulation sleeve 49 keeps the liquid warm and absorbs the condensate outside the nozzle 37 through the absorbent cotton 50. If the temperature control effect is poor, the failed refrigerant flows out. The temperature control component 36 works, the motor 2 47 drives the eccentric wheel 46 to rotate, driving the moving frame 45 and piston rod 44 to move up and down, and the piston plate 43 moves synchronously. When the piston plate 43 rises, the refrigerant inflow pipe 2 41 draws the refrigerant into the buffer tank 42. When the piston plate 43 presses down, the refrigerant enters the temperature control tube 48 through the refrigerant inflow pipe 1 40. The temperature control tube 48 continues to control the temperature of the nozzle 37. This invention sets up a nozzle 37 with a temperature control tube 48 to control the temperature of the nozzle 37 from the inside, improving the efficiency of temperature control. Temperature control component 36 is set up, and the pressure inside buffer box 42 is changed by the lifting and lowering of piston plate 43 to realize the quantitative replacement of refrigerant and ensure stable and long-lasting cooling effect.

[0052] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited thereto. Various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the spirit of the present invention.

Claims

1. A temperature-controlled low-temperature bio-3D printer, comprising a base (1), a mounting frame (2), a horizontal moving module one (3), a vertical moving module (4), a horizontal moving module two (5), a printing platform (6), a printing nozzle (7), a temperature-controlled low-temperature bio-3D printer nozzle device, and a control system; characterized in that, The printing platform (6) includes a mounting plate (8), a support base (9), an elastic element (10), a mounting box (11), a temperature control component (12), and a temperature control component (13); the mounting plate (8) is connected to the moving end of the horizontal moving module (3); the mounting box (11) is connected to the upper end of the mounting plate (8) through the elastic element (10); the temperature control component (12) and the temperature control component (13) are both mounted on the mounting box (11); Temperature control component 1 (12) includes a blower (20), a temperature control plate (21), a temperature control board (22), a cooling element (23), a bracket (24), an air guide frame (25), and an air outlet pipe (26). The temperature control plate (21) is located on the upper end of the mounting box (11). The upper end of the temperature control plate (21) is open, and an air outlet valve (27) is located at the bottom end. The temperature control board (22) is located at the open end of the temperature control plate (21). The bracket (24) is located inside the temperature control plate (21). Multiple sets of cooling elements (23) are provided. The multiple sets of cooling elements (23) are distributed on the bracket (24), and the cooling end contacts the temperature control board (22), and the heating end contacts the air guide frame (25). The air guide frame (25) is located at the bottom of the temperature control plate (21). One end of the air outlet pipe (26) is connected to the blower (20), and the other end extends into the air guide frame (25) and is connected to the air outlet valve (27). Temperature control component 2 (13) includes a drive unit, a lead screw (14), a lifting column (15), a temperature control frame (16), an exhaust pipe (17), and a refrigerator (18); the lead screw (14) is set on the four corners of the mounting box (11) and rotates synchronously through the drive unit; the lifting column (15) corresponds one-to-one with the lead screw (14) and is threaded; the temperature control frame (16) is set on the lifting column (15) and fits around the temperature control plate (21); the exhaust pipe (17) connects the refrigerator (18) and the temperature control frame (16). The temperature-controlled low-temperature biological 3D printer nozzle device includes a mounting plate two (35), a temperature control component three (36), and a nozzle (37); the mounting plate two (35) is set on the moving end of the horizontal moving module two (5); the nozzle (37) is set on the mounting plate two (35), the nozzle (37) has an internal discharge chamber, and an external feed pipe (38), a refrigerant outlet pipe (39), and a refrigerant inflow pipe one (40); the discharge chamber is connected to the feed pipe (38), and has an discharge component (51) and a temperature sensor two inside; the discharge chamber wall has a spiral temperature control pipe (48); the upper end of the temperature control pipe (48) is connected to the refrigerant inflow pipe one (40), and the lower end is connected to the refrigerant outlet pipe (39); the temperature control component three (36) is set on the mounting plate two (35); Temperature control component three (36) includes refrigerant inlet pipe two (41), buffer box (42), piston plate (43), piston rod (44), moving frame (45), eccentric wheel (46), motor two (47), and elastic element two (52); buffer box (42) is mounted on mounting plate two (35); piston plate (43) is slidably mounted inside buffer box (42) in the vertical direction; the lower end of piston rod (44) extends into buffer box (42), connects to piston plate (43), and the upper end connects to moving frame (45); temperature control component two (47) transmits power through the motor. The eccentric wheel (46) is rotatably mounted above the buffer box (42), and its edge is always slidably connected to the moving frame (45); the elastic element two (52) is located between the buffer box (42) and the moving frame (45); the refrigerant inflow pipe two (41) and the refrigerant inflow pipe one (40) are respectively connected to the chamber below the piston plate (43), and the refrigerant inflow pipe two (41) and the refrigerant inflow pipe one (40) are respectively equipped with one-way valves with opposite flow control directions; the refrigerant inflow pipe two (41) is also connected to the external refrigerant storage tank; The nozzle (37) is covered with an insulation sleeve (49); the inner wall of the insulation sleeve (49) is provided with absorbent cotton (50). The cooling element (23) is arranged radially around the axis of the temperature control plate (21) and is engaged with the bracket (24); The air outlet duct (26) is coaxial with the temperature control plate (21); the air guide frame (25) is in a planar spiral shape and is fitted around the air outlet duct (26).

2. The temperature-controlled low-temperature biological 3D printer according to claim 1, characterized in that, The mounting box (11) is equipped with a positioning seat (33); the positioning seat (33) is equipped with a connecting air outlet valve (19) and an air inlet pipe (34); the air outlet valve (19) is connected to the air outlet pipe (26); the air inlet pipe (34) is connected to the air blower (20).

3. The temperature-controlled low-temperature biological 3D printer according to claim 1, characterized in that, The driving components include a motor, a gear 1 (28), a gear 2 (29), a transmission shaft (30), a gear 3 (31), and a gear 4 (32); the lower end of the lead screw (14) extends into the mounting box (11) and corresponds one-to-one with the gear 1 (28), and is keyed; the gear 1 (28) and the gear 2 (29) correspond one-to-one and are meshed; the gear 4 (32) driven by the motor is rotatably set at the center of the mounting box (11); the gear 3 (31) is set in four sets along the tooth surface of the gear 4 (32), meshing with it in sequence, and its position corresponds one-to-one with the gear 2 (29); the two ends of the transmission shaft (30) are keyed to the corresponding gear 2 (29) and gear 3 (31).

4. The temperature-controlled low-temperature biological 3D printer according to claim 1, characterized in that, A second vent valve is provided on the side of the temperature control frame (16) facing the temperature control plate (22).

5. A temperature-controlled low-temperature biological 3D printer according to claim 1, characterized in that, The temperature control plate (22) is made of heat-conducting and cooling materials, and a temperature sensor is installed on the temperature control plate (22).

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