Test method and device of pet detector, electronic equipment and storage medium
By collecting the dark current signal and coincidence signal of the PET detector and using a computer to determine the status, the inconvenience and high cost of existing PET detector quality inspection methods have been solved, realizing an efficient and convenient quality inspection process.
Patent Information
- Application Number
- CN202111468681.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-12-03
- Publication Date
- 2025-12-30
- Estimated Expiration
- 2041-12-03
AI Technical Summary
Existing quality control methods for PET detectors require the use of large, costly rod source systems and radiation sources, leading to inconvenience and increased costs in testing.
By collecting the dark current signals of the photomultiplier tube clusters and silicon photomultipliers of the PET detector, as well as the coincidence signal of the detector ring, the state of the detector is determined by computer, and the quality inspection results are confirmed.
Quality inspection of PET detectors can be achieved without the need for radiation sources and rod source systems, reducing testing costs and improving convenience and testing accuracy.
Smart Images

Figure CN114391860B_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of medical device technology, specifically to a testing method, apparatus, electronic device, and storage medium for a PET detector. Background Technology
[0002] Positron emission tomography-computed tomography (PET-CT) and single-photon emission computed tomography (SPECT) are typical medical imaging devices today. PET-CT mainly uses CT as attenuation correction for PET, and has advantages such as short scan time and low noise, thus replacing transmission scanning and greatly shortening the whole-body PET imaging time.
[0003] Before clinical scanning, PET-CT requires daily quality control (QC) testing to confirm the consistency of the PET detector output signals. Poor consistency or damaged PET detectors will directly affect the quality of PET images. Therefore, a method or device is needed to test the consistency of PET detector output signals.
[0004] In existing technologies, a rod source system is usually set up behind the PET main unit frame. During testing, the radiation source emitted by the rod source system is required to conduct the test. The rod source system is large in size, expensive, and very inconvenient to install, transport, and use, which brings great inconvenience to the daily-qc test of PET detectors. Summary of the Invention
[0005] To address the aforementioned issues, embodiments of this application provide a testing method, apparatus, electronic device, and storage medium for daily quality inspection of PET detectors.
[0006] In a first aspect, this application provides a testing method for a PET detector, comprising:
[0007] Acquire the first dark current signal of the photomultiplier tube cluster of the PET detector, and determine the first state of the photomultiplier tube cluster based on the first dark current signal; or, acquire the second dark current signal of the silicon photomultiplier of the PET detector, and determine the second state of the silicon photomultiplier based on the second dark current signal.
[0008] Acquire at least one set of coincidence signals from the detector loop of the PET detector, and determine the third state of the coincidence signal link based on the coincidence signals;
[0009] The test result of the PET detector is determined by combining either the first state or the second state, as well as the third state.
[0010] Optionally, in the above method, the photomultiplier cluster includes multiple photomultipliers;
[0011] Determining the first state of the photomultiplier tube cluster based on the first dark current signal includes:
[0012] The first dark current signal collected from each photomultiplier tube is counted to obtain the first count of each photomultiplier tube;
[0013] The first state of the photomultiplier tube cluster is determined based on the first count of each photomultiplier tube.
[0014] Optionally, in the above method, counting the first dark current signals acquired from each photomultiplier tube to obtain the first count of each photomultiplier tube includes:
[0015] Based on the markings of each of the first dark current signals, the photomultiplier tubes of each first dark current signal are determined.
[0016] Based on the photomultiplier tube affiliation of each first dark current signal, the first dark current signals collected from each photomultiplier tube are counted to obtain the first count of each photomultiplier tube.
[0017] Optionally, in the above method, determining the first state of the photomultiplier tube cluster based on the first count of each photomultiplier tube includes:
[0018] If the first count of a photomultiplier tube is equal to the first system threshold, then the first state of the photomultiplier tube is normal; otherwise, the first state of the photomultiplier tube is abnormal.
[0019] If all photomultiplier tubes are functioning normally, then the first state of the photomultiplier tube cluster is determined to be normal.
[0020] Optionally, in the above method, the silicon photomultiplier includes multiple output units;
[0021] Determining the second state of the silicon photomultiplier based on the second dark current signal includes:
[0022] The second dark current signal output by each output unit is counted to obtain the second count of each output unit.
[0023] If the second count of an output unit reaches the second system threshold, the state of the output unit is normal; otherwise, the state of the output unit is abnormal.
[0024] If all output units are in a normal state, then the second state of the silicon photomultiplier is determined to be normal.
[0025] Optionally, in the above method, acquiring at least one set of coincidence signals from the detector ring of the PET detector includes:
[0026] Using a data acquisition board, at least one set of coincidence signals sent by the detector ring are acquired, wherein the coincidence signals are emitted in pairs by detector channels that are positioned opposite each other in the detector ring;
[0027] Determining the third state of the conforming signal link based on the conforming signal includes:
[0028] The data integration board receives at least one set of matching signals sent by the data acquisition board. If the matching signals are determined to be paired and arrive at the data integration board within a preset time, the third state of the matching signal link is determined to be normal; otherwise, the third state of the matching signal link is determined to be abnormal.
[0029] Optionally, in the above method, determining the test result of the PET detector by combining the first state, any one of the second state, and the third state includes:
[0030] If both the first state and the third state are determined to be normal, then the test result of the PET detector is determined to be passed; otherwise, the test result of the PET detector is determined to be failed.
[0031] or,
[0032] If both the second and third states are determined to be normal, the test result of the PET detector is determined to be passed; otherwise, the test result of the PET detector is determined to be failed.
[0033] Secondly, this application provides a testing apparatus for a PET detector, the apparatus comprising:
[0034] The first acquisition and judgment unit is used to acquire the first dark current signal of the photomultiplier tube cluster of the PET detector, and determine the first state of the photomultiplier tube cluster based on the first dark current signal.
[0035] Alternatively, it can be used to acquire the second dark current signal of the silicon photomultiplier of the PET detector, and determine the second state of the silicon photomultiplier based on the second dark current signal;
[0036] The second acquisition and judgment unit is used to acquire at least one set of coincidence signals of the detector ring of the PET detector, and determine the third state of the coincidence signal link based on the coincidence signals;
[0037] The test result determination unit is used to combine any one of the first state and the second state, as well as the third state, to determine the test result of the PET detector.
[0038] Fourthly, embodiments of this application also provide an electronic device, including: a processor; and a memory arranged to store computer-executable instructions, which, when executed, cause the processor to perform any of the methods described above.
[0039] Fifthly, embodiments of this application also provide a computer-readable storage medium that stores one or more programs, which, when executed by an electronic device including multiple applications, cause the electronic device to perform any of the methods described above.
[0040] The above-described technical solutions adopted in the embodiments of this application can achieve the following beneficial effects:
[0041] This application addresses the current technology where quality inspection of PET detectors requires the use of a radioactive source, resulting in high testing costs. Furthermore, the large size, heavy weight, and difficult installation and relocation of the radioactive source rod system further complicate the process. This application proposes a testing method for PET detectors. This method utilizes the dark current signal emitted by the photomultiplier tube cluster or silicon photomultiplier of the PET detector after applying a bias voltage, and the characteristic of the detector ring emitting a coincidence signal in pairs. By determining the state of the photomultiplier tube cluster, silicon photomultiplier, and coincidence signal link, the quality inspection result of the PET detector can be determined. This application achieves quality inspection of PET detectors using computer methods without requiring a radioactive source (i.e., without a rod source system), leveraging the inherent characteristics of the PET detector itself. This significantly reduces the cost of PET detector quality inspection, eliminates the need to move the rod source system during each use, greatly improves the convenience of PET detector quality inspection, and offers high testing accuracy and ease of use. Attached Figure Description
[0042] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings:
[0043] Figure 1 (include Figure 1 -a and Figure 1-b) shows two schematic diagrams of the structure of a PET-CT scanner according to the prior art;
[0044] Figure 2 A flowchart illustrating a testing method for a PET detector according to an embodiment of this application is shown.
[0045] Figure 3 A schematic diagram of the structure of a nuclear medicine PET detector is shown.
[0046] Figure 4 A schematic diagram of a silicon photomultiplier for a nuclear medicine PET detector is shown.
[0047] Figure 5 The waveform of noise acquired after applying a bias voltage to a silicon photomultiplier in a nuclear medicine PET detector is shown.
[0048] Figure 6 A schematic diagram of the process for confirming the third state of a signal link according to an embodiment of this application is shown;
[0049] Figure 7 A schematic diagram of the detector ring structure of a nuclear medicine PET detector is shown;
[0050] Figure 8 (include Figure 8 -a~ Figure 8 -f) shows the spectral and data analysis results confirming the first state of a photomultiplier tube cluster according to an embodiment of this application;
[0051] Figure 9 A schematic diagram of the surface structure of a silicon photomultiplier according to an embodiment of this application is shown;
[0052] Figure 10 (include Figure 10 -a~ Figure 10 -c) shows the spectral analysis results confirming the first state of a silicon photomultiplier according to an embodiment of this application;
[0053] Figure 11 A schematic diagram of the structure of a test apparatus for a PET detector according to an embodiment of this application is shown;
[0054] Figure 12 This is a schematic diagram of the structure of an electronic device according to an embodiment of this application. Detailed Implementation
[0055] To make the objectives, technical solutions, and advantages of this application clearer, the technical solutions of this application will be clearly and completely described below in conjunction with specific embodiments and corresponding drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0056] The technical solutions provided by the various embodiments of this application are described in detail below with reference to the accompanying drawings.
[0057] There are two main types of existing quality inspection and testing schemes for PET detectors. The first type is, for example... Figure 1 of Figure 1 As shown in -a, from Figure 1 As can be seen from -a, the CT main frame and the PET main frame are relatively independent. A rod source system is set behind the PET main frame, and this rod source system is an integral structure with the PET main frame. In this configuration, the rod source system is installed behind the PET main frame, resulting in a large overall size of the PET frame, which is inconvenient for installation and transportation, and has high manufacturing costs. In addition, it is necessary to purchase radiation sources for quality inspection and testing, which increases the testing costs.
[0058] The second form, such as Figure 1 of Figure 1 -b shows that from Figure 1 As can be seen from the -b diagram, the CT main unit gantry, the PET main unit gantry, and the rod source system are all relatively independent. In this configuration, the rod source system needs to be moved from one location to the PET gantry for quality control testing. After the testing is completed, the rod source system must be removed before clinical scanning can be performed. Similarly, this configuration also requires the purchase of radiation sources for quality control testing.
[0059] Because PET detectors require frequent quality inspections, often daily, existing inspection methods are very inconvenient.
[0060] The concept of this application is to propose a testing method that utilizes the inherent characteristics of PET detectors to address the aforementioned issues. This method involves data acquisition via collecting the dark current signal output from a photomultiplier tube (PMT) to determine if the PMT is functioning correctly; or, data acquisition via collecting the dark current signal output from a silicon photomultiplier to determine if the silicon photomultiplier is functioning correctly. The method also uses self-emitted electron signals to determine if the coincidence signal link of the PET detector is functioning correctly. Finally, by combining all the judgment results, the test result for quality inspection of the PET detector is determined.
[0061] Figure 2This diagram illustrates a flow chart of a testing method for a PET detector according to an embodiment of this application. Figure 2 It can be seen that this application includes at least step S210 or step S220, and steps S230 to S240. It should be noted that either step S210 or step S220 can be performed, and there is an "or" relationship between them. This is because in a PET detector, photomultiplier tube clusters and silicon photomultipliers are two options. Both are currently mainstream technologies, and it can be understood that their functions are the same, but their materials are different. Therefore, this application is applicable to PET detectors containing photomultiplier tube clusters as well as PET detectors containing silicon photomultipliers. During testing, whether to perform step S210 or step S220 can be selected according to the type of detector.
[0062] Step S210: Acquire the first dark current signal of the photomultiplier tube cluster of the PET detector, and determine the first state of the photomultiplier tube cluster based on the first dark current signal.
[0063] Figure 3 A schematic diagram of the structure of a nuclear medicine PET detector is shown. Figure 3 As can be seen, in the nuclear medicine PET detector 300, the structure 301 close to the observer is the detector crystal; the structure 302 far from the observer is a photomultiplier tube cluster, which includes four photomultiplier tubes, denoted as photomultiplier tube A, photomultiplier tube B, photomultiplier tube C (not directly shown in the figure due to visual reasons) and photomultiplier tube D.
[0064] When a bias voltage is applied to the photomultiplier tube of a nuclear medicine PET detector, it will output current even without receiving a light-emitting signal. This is called dark current. This application uses these dark currents to detect the state of the photomultiplier tube of the PET detector.
[0065] Specifically, the number of dark current signals from each photomultiplier tube (PMT) can be calculated. After applying a bias voltage to the PMT, the expected number of dark current signals collected from each PMT should be 100,000. To distinguish this from the dark current signals generated by silicon photomultipliers, the dark current signals from the PMT are designated as the first dark current signal. If, through acquisition and counting, the number of dark current signals from a PMT reaches the expected value (e.g., 100,000), then the PMT is normal. If the number of dark current signals from a PMT is 0, then the PMT is abnormal. If all PMTs in the PMT cluster (A, B, C, and D) are in normal condition, then the overall first state of the PMT cluster is normal. If one or more PMTs are in abnormal condition, then the overall first state of the PMT cluster is abnormal.
[0066] It should be noted that the number of dark current signals collected from a photomultiplier tube can only be one of two cases: the system threshold, which we assume to be 100,000, or 0. There is no intermediate value. This is because if a photomultiplier tube is functioning normally, the number of dark current signals collected from it should be the system threshold; if a photomultiplier tube is malfunctioning, no signal passes through it, and the number of dark current signals collected will be 0.
[0067] Alternatively, step S220: acquire the second dark current signal of the silicon photomultiplier of the PET detector, and determine the second state of the silicon photomultiplier based on the second dark current signal.
[0068] Figure 4 A schematic diagram of a silicon photomultiplier for a nuclear medicine PET detector is shown. Figure 4 As can be seen, the silicon photomultiplier 301 includes a crystal 301-1, a silicon photomultiplier body 301-2, and a data output circuit 301-3. Here, a crystal 301-1 can be regarded as a transmitting unit.
[0069] When a bias voltage is applied to the silicon photomultiplier of a nuclear medicine PET detector, it will output current even without receiving a light signal. This current is caused by electrons avalanche in a strong electric field, and this noise is intermittent. Setting the threshold below this level can effectively collect the noise. Figure 5 As shown, this is dark current.
[0070] Based on the second dark current signal output by the silicon photomultiplier, it can be determined whether the silicon photomultiplier is in a normal state. Specifically, based on the dark current signal output by the silicon photomultiplier, the dark current signal of each output unit is counted. If the second count of the dark current signal of an output unit reaches the system's required threshold, such as 10M / 16mm... 2 If the count is zero, the output unit is confirmed to be normal; if an output unit is found to have no count, the output unit is determined to be abnormal.
[0071] The second state of the entire silicon photomultiplier is normal only when all output units are in normal condition; if one or more output units are in abnormal condition, the second state of the entire silicon photomultiplier is abnormal.
[0072] Step S230: Acquire at least one set of coincidence signals from the detector loop of the PET detector, and determine the third state of the coincidence signal link based on the coincidence signals.
[0073] A coincidence signal link can be understood as a link formed by the transmission and reception of coincidence signals according to certain rules. Once a PET detector is manufactured, this signal link is formed. Under normal conditions, the PET detector requires the coincidence signals to be transmitted and received in the form defined by this signal link.
[0074] In some embodiments of this application, a data acquisition board is used to acquire at least one set of coincidence signals sent by the detector ring, wherein the coincidence signals are sent in pairs by detector channels with opposite positions in the detector ring; a data integration board is used to receive at least one set of coincidence signals sent by the data acquisition board; if it is determined that the coincidence signals are paired and arrive at the data integration board according to a preset time, then the third state of the coincidence signal link is determined to be normal; otherwise, the third state of the coincidence signal link is determined to be abnormal.
[0075] The determination of the third state of the coincident signal link can be based on the following process: The data acquisition board receives one or more sets of coincident signals simultaneously transmitted by the corresponding channel of the detector loop. The data acquisition board acquires the coincident signals and then sends them to the data integration board for data analysis. The data integration board outputs the analysis results, which include, but are not limited to, the third state of the coincident signal link. This process can be referenced. Figure 6 .
[0076] Among them, the matching information is in pairs, emitted by opposing channels on the detector ring, such as... Figure 7 As shown, a detector ring includes 24 channels. Channel 1 is opposite to channel 13, channel 2 is opposite to channel 14, and so on. Channel 24 is opposite to channel 12. Channel 1 and channel 13 simultaneously emit a set or a pair of coincident signals.
[0077] The data integration board performs data analysis on the conformance signal to determine whether each channel is normal. If all channels are normal, the third state of the conformance signal link is determined to be normal; otherwise, it is abnormal.
[0078] Table 1 shows the results of determining the third state of the conforming signal link according to an embodiment of this application. As can be seen from Table 1, it is necessary to determine not only whether the single channel state is normal, but also whether the state of the conforming signal link is normal.
[0079] Table 1
[0080]
[0081] Step S240: Combine any one of the first and second states, and the third state, to determine the test result of the PET detector.
[0082] Finally, the first and third states are combined, or the second and third states are combined, to determine the test result of the PET detector. Specifically, if both the first and third states are normal, or both the second and third states are normal, the test result of the PET detector is determined to be pass; otherwise, the test result of the PET detector is determined to be fail.
[0083] In some embodiments of this application, the output test results can provide specific reasons for the failure of the test, which helps staff to judge the fault.
[0084] In some embodiments of this application, steps S210 and S220 can be executed in an alternative manner, and steps S210 or S220-S230 can be performed sequentially. That is, first, a first state or a second state is determined. If the first state or the second state is abnormal, the test result of the daily quality inspection of the PET detector is directly returned as failing, allowing the staff to troubleshoot and re-enter the test. If the first state or the second state is normal, then proceed to step S230. If the third state is abnormal, the test result of the PET detector is directly returned as failing, allowing the staff to troubleshoot and re-enter the test. If the third state is normal, then proceed to step S240.
[0085] In some embodiments of this application, to understand all faults of the PET detector at once, steps S210 or S220-S230 can be performed in parallel, directly outputting all faults at once. Figure 2As shown in the diagram, this application proposes a testing method for PET detectors. This method utilizes the characteristics of the photomultiplier tube clusters or silicon photomultipliers in PET detectors, which emit dark current signals after a bias voltage is applied, and the paired emission of coincidence signals from the detector rings. By analyzing these characteristics, the state of the photomultiplier tube clusters or silicon photomultipliers, and the coincidence signal link, can be determined, thereby determining the test results of the PET detector. This application achieves daily quality inspection testing of PET detectors using computer methods, without requiring a radiation source (i.e., without a rod source system). This significantly reduces the cost of quality inspection testing for PET detectors. The rod source system does not need to be moved during each use, greatly improving the convenience of quality inspection for PET detectors. Furthermore, the method offers high testing accuracy and ease of use.
[0086] In some embodiments of this application, the photomultiplier cluster includes multiple photomultipliers; determining the first state of the photomultiplier tube cluster based on the first dark current signal includes: counting the first dark current signals collected from each photomultiplier tube to obtain a first count of each photomultiplier tube; and determining the first state of the photomultiplier tube cluster based on the first count of each photomultiplier tube. Specifically, counting the first dark current signals collected from each photomultiplier tube to obtain the first count of each photomultiplier tube includes: determining the photomultiplier tube affixed to each first dark current signal based on the marking of each first dark current signal; and counting the first dark current signals collected from each photomultiplier tube based on the photomultiplier tube affixed to each first dark current signal to obtain the first count of each photomultiplier tube. The step of determining the first state of the photomultiplier tube cluster based on the first count of each photomultiplier tube includes: if the first count of a photomultiplier tube is a first system threshold, then the first state of the photomultiplier tube is normal; otherwise, the first state of the photomultiplier tube is abnormal; if all photomultiplier tubes are normal, then the first state of the photomultiplier tube cluster is determined to be normal.
[0087] The following is a method for determining the first state of a photomultiplier tube cluster. The first dark current signal output by each photomultiplier tube is marked. Photomultiplier tubes A, B, C, and D can be denoted as A, B, C, and D, respectively. The position coordinates (X, Y) of the first dark current signal can be obtained using the centroid method. The XOY coordinate system direction can be referenced. Figure 3 This allows us to determine which photomultiplier tube the first dark current signal originated from. The specific calculation formula is as follows:
[0088] X=(A+C) / E, Y=(C+D) / E, where E=A+B+C+D.
[0089] Using the above formula, the location information of each first dark current signal is counted and statistically analyzed to determine which photomultiplier tube (PMT) acquired each signal. This allows for data analysis and the output of a spectrum to confirm the functionality of individual PMTs. Furthermore, if all PMTs are in normal condition, the first state of the PMT cluster is considered normal. If a PMT has no count of first dark current signals, its state is deemed abnormal. If one or more PMTs in a PMT cluster are in abnormal condition, the first state of the entire PMT cluster is deemed abnormal.
[0090] In some embodiments of this application, the specific photomultiplier tube that is malfunctioning can be output to facilitate troubleshooting by staff.
[0091] Table 2 shows the test results for multiple scenarios confirming the first state of the photomultiplier tube cluster. Figure 8 (include Figure 8 -a~ Figure 8 -f) shows the spectral and data analysis results confirming the first state of a photomultiplier tube cluster according to an embodiment of this application, in conjunction with Table 2 and Figure 8 ,from Figure 8 -a and Figure 8 As can be seen from -b, the first count of the first dark current signal collected from photomultiplier tubes A, B, C, and D is 100,000, and the spectrum shows that photomultiplier tubes A, B, C, and D all have signals. Therefore, the first state of the photomultiplier tube cluster in the computer output is normal. Similarly, from... Figure 8 -c and Figure 8 As can be seen from -d, the first count of the first dark current signal collected from photomultiplier tubes A, B, C, and D is all 0, and the spectrum shows that there is no signal from photomultiplier tubes A, B, C, and D. Therefore, the first state of the photomultiplier tube cluster in the computer output is abnormal. Figure 8 -e and Figure 8 As can be seen from -f, the first count of the first dark current signal collected from photomultiplier tubes A, C, and D is 100,000, while the first count of the first dark current signal collected from photomultiplier tube B is 0. Furthermore, the spectrum shows that photomultiplier tubes A, C, and D all have signals, while photomultiplier tube B has no signal. Therefore, the first state of the photomultiplier tube cluster in the computer output is abnormal.
[0092] Table 2
[0093]
[0094] In some embodiments of this application, the silicon photomultiplier includes multiple output units; determining the second state of the silicon photomultiplier based on the second dark current signal includes:
[0095] The second dark current signal output by each output unit is counted to obtain the second count of each output unit; if the second count of an output unit reaches the second system threshold, the state of the output unit is normal; otherwise, the state of the output unit is abnormal; if the state of each output unit is normal, the second state of the silicon photomultiplier is determined to be normal.
[0096] The following is a recommended method for confirming the second state of a silicon photomultiplier. Figure 9 A schematic diagram of the surface structure of a silicon photomultiplier according to an embodiment of this application is shown. Figure 9 As can be seen from the diagram, a small square can be considered an output unit of the silicon photomultiplier, assuming the side length of an output unit is 4mm. When confirming the second state of the silicon photomultiplier, the second dark current signal of each output unit is counted based on the second dark current signal output by the silicon photomultiplier. If the second count of the second dark current signal of an output unit reaches the system requirement, i.e., the second system threshold, assuming it is 10M / 16mm... 2 If the count of all output units is 0, then the status of that output unit is confirmed to be normal. If the status of all output units is normal, then the second status of the silicon photomultiplier is normal. If, among all output units, one or more output units have a second count of 0, then the status of that output unit is confirmed to be abnormal, and the second status of the silicon photomultiplier is abnormal.
[0097] Table 3 shows the test results for multiple cases confirming the second state of the silicon photomultiplier. Figure 10 (include Figure 10 -a~ Figure 10 -c) shows the spectral analysis results confirming the first state of a silicon photomultiplier according to an embodiment of this application, in conjunction with Table 3 and Figure 10 ,from Figure 10 As can be seen from -a, each output unit has a signal output. Data analysis reveals that the second count of the second dark current signal for each output unit is 10M / 16mm. 2 Therefore, the second state of the silicon photomultiplier in the computer output is normal; from Figure 10-b indicates that none of the output units output a signal. Data analysis shows that the second count of the second dark current signal for each output unit is 0. Therefore, the second state of the silicon photomultiplier in the computer output is abnormal. Figure 10 As can be seen from -c, the circled output unit has no signal output. After data analysis, it can be found that the second count of the second dark current signal of this output unit is 0. Therefore, the second state of the silicon photomultiplier in the computer output result is abnormal.
[0098] Table 3
[0099]
[0100] Figure 11 A schematic diagram of a testing apparatus for a PET detector according to an embodiment of this application is shown. Figure 11 It can be seen that the device 1100 includes:
[0101] The first acquisition and judgment unit 1101 is used to acquire the first dark current signal of the photomultiplier tube cluster of the PET detector and determine the first state of the photomultiplier tube cluster based on the first dark current signal; or, it is used to acquire the second dark current signal of the silicon photomultiplier of the PET detector and determine the second state of the silicon photomultiplier based on the second dark current signal.
[0102] The second acquisition and judgment unit 1102 is used to acquire at least one set of coincidence signals of the detector ring of the PET detector, and determine the third state of the coincidence signal link based on the coincidence signals.
[0103] The test result determination unit 1103 is used to combine any one of the first state and the second state, as well as the third state, to determine the test result of the PET detector.
[0104] In some embodiments of this application, in the above-described device, the photomultiplier cluster includes multiple photomultipliers; the first acquisition and judgment unit 1101 is used to count the first dark current signal acquired from each photomultiplier tube to obtain the first count of each photomultiplier tube; and to determine the first state of the photomultiplier tube cluster based on the first count of each photomultiplier tube.
[0105] In some embodiments of this application, in the above-described apparatus, the first acquisition and judgment unit 1101 is used to determine the photomultiplier tube affiliation of each first dark current signal according to the marking of each first dark current signal in the first dark current signal; and to count the first dark current signals acquired from each photomultiplier tube according to the photomultiplier tube affiliation of each first dark current signal to obtain the first count of each photomultiplier tube.
[0106] In some embodiments of this application, in the above-described device, the first acquisition and judgment unit 1101 is used to determine that the first state of a photomultiplier tube is normal if the first count of a photomultiplier tube is equal to the first system threshold, otherwise the first state of the photomultiplier tube is abnormal; and when all photomultiplier tubes are normal, the first state of the photomultiplier tube cluster is determined to be normal.
[0107] In some embodiments of this application, in the above-described device, the silicon photomultiplier includes multiple output units; a first acquisition and judgment unit 1101 is used to count the second dark current signal output by each output unit to obtain the second count of each output unit; if the second count of an output unit reaches a second system threshold, the state of the output unit is normal; otherwise, the state of the output unit is abnormal; if the state of each output unit is normal, the second state of the silicon photomultiplier is determined to be normal.
[0108] In some embodiments of this application, in the above-described device, the second acquisition and judgment unit 1102 is used to acquire at least one set of coincidence signals sent by the detector ring using a data acquisition board, wherein the coincidence signals are sent in pairs by detector channels with opposite positions in the detector ring; it is also used to receive at least one set of coincidence signals sent by the data acquisition board using a data integration board, and if it is determined that the coincidence signals are paired and arrive at the data integration board according to a preset time, then the third state of the coincidence signal link is determined to be normal; otherwise, the third state of the coincidence signal link is determined to be abnormal.
[0109] In some embodiments of this application, in the above-described apparatus, the test result determination unit 1103 determines that the test result of the PET detector is passed if both the first state and the third state are normal; otherwise, it determines that the test result of the PET detector is failed; or, if both the second state and the third state are normal, it determines that the test result of the PET detector is passed; otherwise, it determines that the test result of the PET detector is failed.
[0110] Figure 12 This is a schematic diagram of the structure of an electronic device according to an embodiment of this application. Please refer to it. Figure 12At the hardware level, the electronic device includes a processor, and optionally also includes an internal bus, a network interface, and memory. The memory may include main memory, such as high-speed random-access memory (RAM), or non-volatile memory, such as at least one disk drive. Of course, the electronic device may also include other hardware required for other business operations.
[0111] The processor, network interface, and memory can be interconnected via an internal bus, which can be an ISA (Industry Standard Architecture) bus, a PCI (Peripheral Component Interconnect) bus, or an EISA (Extended Industry Standard Architecture) bus, etc. This bus can be divided into address bus, data bus, control bus, etc. For ease of representation, Figure 12 The symbol is represented by a single double-headed arrow, but this does not mean that there is only one bus or one type of bus.
[0112] Memory is used to store programs. Specifically, programs may include program code, which includes computer operation instructions. Memory may include main memory and non-volatile memory, and provides instructions and data to the processor.
[0113] The processor reads the corresponding computer program from non-volatile memory into main memory and then runs it, forming the daily quality inspection test device for PET detectors at the logical level. The processor executes the program stored in memory and specifically performs the following operations:
[0114] Acquire the first dark current signal of the photomultiplier tube cluster of the PET detector, and determine the first state of the photomultiplier tube cluster based on the first dark current signal; or, acquire the second dark current signal of the silicon photomultiplier of the PET detector, and determine the second state of the silicon photomultiplier based on the second dark current signal.
[0115] Acquire at least one set of coincidence signals from the detector loop of the PET detector, and determine the third state of the coincidence signal link based on the coincidence signals;
[0116] The test result of the PET detector is determined by combining either the first state or the second state, as well as the third state.
[0117] The above is as stated in this application. Figure 11The method executed by the daily quality inspection testing device for PET detectors disclosed in the illustrated embodiment can be applied to a processor or implemented by a processor. The processor may be an integrated circuit chip with signal processing capabilities. During implementation, each step of the above method can be completed by integrated logic circuits in the processor's hardware or by instructions in software form. The processor can be a general-purpose processor, including a Central Processing Unit (CPU), a Network Processor (NP), etc.; it can also be a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), a Field-Programmable Gate Array (FPGA), or other programmable logic devices, discrete gate or transistor logic devices, or discrete hardware components. It can implement or execute the methods, steps, and logic block diagrams disclosed in the embodiments of this application. The general-purpose processor can be a microprocessor or any conventional processor. The steps of the method disclosed in the embodiments of this application can be directly embodied in the execution of a hardware decoding processor, or executed by a combination of hardware and software modules in the decoding processor. The software module can reside in a mature storage medium in the field, such as random access memory, flash memory, read-only memory, programmable read-only memory, electrically erasable programmable memory, or registers. This storage medium is located in memory, and the processor reads information from the memory and, in conjunction with its hardware, completes the steps of the above method.
[0118] The electronic device can also perform Figure 11 The method for implementing the daily quality inspection test device for PET detectors is described, and the implementation of the daily quality inspection test device for PET detectors is described. Figure 11 The functions of the embodiments shown are not described in detail here.
[0119] This application also proposes a computer-readable storage medium that stores one or more programs, the programs including instructions that, when executed by an electronic device including multiple applications, enable the electronic device to perform... Figure 11 The method executed by the testing device for daily quality inspection of the PET detector in the illustrated embodiment is specifically used to perform the following:
[0120] Acquire the first dark current signal of the photomultiplier tube cluster of the PET detector, and determine the first state of the photomultiplier tube cluster based on the first dark current signal; or, acquire the second dark current signal of the silicon photomultiplier of the PET detector, and determine the second state of the silicon photomultiplier based on the second dark current signal.
[0121] Acquire at least one set of coincidence signals from the detector loop of the PET detector, and determine the third state of the coincidence signal link based on the coincidence signals;
[0122] The test result of the PET detector is determined by combining either the first state or the second state, as well as the third state.
[0123] Those skilled in the art will understand that embodiments of this application can be provided as methods, systems, or computer program products. Therefore, this application can take the form of a completely hardware embodiment, a completely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, this application can take the form of a computer program product embodied on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.
[0124] This application is described with reference to flowchart illustrations and / or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of this application. It will be understood that each block of the flowchart illustrations and / or block diagrams, and combinations of blocks in the flowchart illustrations and / or block diagrams, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, special-purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, generate instructions for implementing the flowchart... Figure 1 One or more processes and / or boxes Figure 1 A device that provides the functions specified in one or more boxes.
[0125] These computer program instructions may also be stored in a computer-readable storage medium that can direct a computer or other programmable data processing device to function in a particular manner, such that the instructions stored in the computer-readable storage medium produce an article of manufacture including instruction means, which are implemented in a process Figure 1 One or more processes and / or boxes Figure 1 The function specified in one or more boxes.
[0126] These computer program instructions may also be loaded onto a computer or other programmable data processing equipment to cause a series of operational steps to be performed on the computer or other programmable equipment to produce a computer-implemented process, thereby providing instructions that execute on the computer or other programmable equipment for implementing the process. Figure 1 One or more processes and / or boxes Figure 1 The steps of the function specified in one or more boxes.
[0127] In a typical configuration, a computing device includes one or more processors (CPU), input / output interfaces, network interfaces, and memory.
[0128] Memory may include non-persistent storage in computer-readable media, such as random access memory (RAM) and / or non-volatile memory, such as read-only memory (ROM) or flash RAM. Memory is an example of computer-readable media.
[0129] Computer-readable media includes both permanent and non-permanent, removable and non-removable media that can store information using any method or technology. Information can be computer-readable instructions, data structures, modules of programs, or other data. Examples of computer storage media include, but are not limited to, phase-change memory (PRAM), static random access memory (SRAM), dynamic random access memory (DRAM), other types of random access memory (RAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), flash memory or other memory technologies, CD-ROM, digital versatile optical disc (DVD) or other optical storage, magnetic tape, magnetic magnetic disk storage or other magnetic storage devices, or any other non-transferable medium that can be used to store information accessible by a computing device. As defined herein, computer-readable media does not include transient computer-readable media, such as modulated data signals and carrier waves.
[0130] It should also be noted that the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.
[0131] Those skilled in the art will understand that embodiments of this application can be provided as methods, systems, or computer program products. Therefore, this application can take the form of a completely hardware embodiment, a completely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, this application can take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.
[0132] The above description is merely an embodiment of this application and is not intended to limit the scope of this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of the claims of this application.
Claims
1. A method of testing a PET detector, characterized by, The method comprises the following steps: collecting a first dark current signal of a photomultiplier tube cluster of the PET detector, and determining a first state of the photomultiplier tube cluster according to the first dark current signal; or collecting a second dark current signal of a silicon photomultiplier of the PET detector, and determining a second state of the silicon photomultiplier according to the second dark current signal; collecting at least one group of coincidence signals of a detector ring of the PET detector, and determining a third state of a coincidence signal link according to the coincidence signals; determining a test result of the PET detector in combination with any one of the first state and the second state and the third state; the photomultiplier tube cluster comprises a plurality of photomultiplier tubes; the step of determining the first state of the photomultiplier tube cluster according to the first dark current signal comprises the following steps: counting the first dark current signals collected from each photomultiplier tube to obtain a first count number of each photomultiplier tube; determining the first state of the photomultiplier tube cluster according to the first count number of each photomultiplier tube; the silicon photomultiplier comprises a plurality of output units; the step of determining the second state of the silicon photomultiplier according to the second dark current signal comprises the following steps: counting the second dark current signals output by each output unit respectively to obtain a second count number of each output unit; if the second count number of an output unit reaches a second system threshold value, the state of the output unit is normal, otherwise, the state of the output unit is abnormal; if the state of each output unit is normal, it is determined that the second state of the silicon photomultiplier is normal; the step of collecting at least one group of coincidence signals of the detector ring of the PET detector comprises the following steps: collecting at least one group of coincidence signals sent by the detector ring by using a data collection board, wherein the coincidence signals are emitted by pairs of detector channels of the detector ring whose positions are opposite; the step of determining the third state of the coincidence signal link according to the coincidence signals comprises the following steps: receiving at least one group of coincidence signals sent by the data collection board by using a data integration board, and if it is determined that the coincidence signals are paired and arrive at the data integration board according to a preset time, it is determined that the third state of the coincidence signal link is normal, otherwise, it is determined that the third state of the coincidence signal link is abnormal.
2. The method of claim 1, wherein, the step of counting the first dark current signals collected from each photomultiplier tube to obtain a first count number of each photomultiplier tube comprises the following steps: determining the photomultiplier tube attribution of each first dark current signal according to the mark of each first dark current signal in the first dark current signal respectively; counting the first dark current signals collected from each photomultiplier tube according to the photomultiplier tube attribution of each first dark current signal to obtain a first count number of each photomultiplier tube.
3. The method of claim 1, wherein, the step of determining the first state of the photomultiplier tube cluster according to the first count number of each photomultiplier tube comprises the following steps: if the first count number of a photomultiplier tube is a first system threshold value, the first state of the photomultiplier tube is normal, otherwise, the first state of the photomultiplier tube is abnormal; in the case that each photomultiplier tube is normal, it is determined that the first state of the photomultiplier tube cluster is normal.
4. The method of claim 1, wherein, The test result of the PET detector is determined by combining any one of the first state and the second state, and the third state, including: In a case where it is determined that the first state and the third state are both normal, it is determined that the test result of the PET detector is passed; otherwise, it is determined that the test result of the PET detector is failed. Or, In a case where it is determined that the second state and the third state are both normal, it is determined that the test result of the PET detector is passed; otherwise, it is determined that the test result of the PET detector is failed.
5. A testing device for a PET detector, characterized in that The device includes: The first acquisition and judgment unit is configured to acquire a first dark current signal of a photomultiplier tube cluster of the PET detector, and determine a first state of the photomultiplier tube cluster according to the first dark current signal; or acquire a second dark current signal of a silicon photomultiplier of the PET detector, and determine a second state of the silicon photomultiplier according to the second dark current signal; The second acquisition and judgment unit is configured to acquire at least one group of coincidence signals of a detector ring of the PET detector, and determine a third state of a coincidence signal link according to the coincidence signals; The test result determination unit is configured to determine a test result of the PET detector by combining any one of the first state and the second state, and the third state; The photomultiplier tube cluster includes a plurality of photomultiplier tubes; the first acquisition and judgment unit is configured to count the first dark current signals acquired from the photomultiplier tubes to obtain first count quantities of the photomultiplier tubes; and determine the first state of the photomultiplier tube cluster according to the first count quantities of the photomultiplier tubes; The silicon photomultiplier includes a plurality of output units; the first acquisition and judgment unit is configured to count the second dark current signals output by the output units respectively to obtain second count quantities of the output units; if the second count quantity of an output unit reaches a second system threshold, the state of the output unit is normal, otherwise, the state of the output unit is abnormal; and if the states of all the output units are normal, it is determined that the second state of the silicon photomultiplier is normal; The second acquisition and judgment unit is configured to acquire at least one group of coincidence signals sent by a detector ring by using a data acquisition board, wherein the coincidence signals are emitted by positionally opposite detector channels of the detector ring; and receive at least one group of coincidence signals sent by the data acquisition board by using a data integration board; if it is determined that the coincidence signals are paired and arrive at the data integration board according to a preset time, it is determined that the third state of the coincidence signal link is normal, otherwise, it is determined that the third state of the coincidence signal link is abnormal.
6. An electronic device, comprising: A processor; and a memory arranged to store computer-executable instructions that, when executed, cause the processor to perform the method of any one of claims 1-4. A processor; and a memory arranged to store computer-executable instructions that, when executed, cause the processor to perform the method of any one of claims 1-4.
7. A computer-readable storage medium storing one or more programs, which when executed by an electronic device including multiple applications, cause the electronic device to perform any of the methods of claims 1-4.
Citation Information
Patent Citations
SiPM-based multi-photon detection method
CN106706127A
Sample analyzer and sample analyzing method thereof
CN107202903A