Sample analyzer and sample injection device

Abstract

A sample analyzer and a sample injection device, the sample injection device comprises a mounting seat, an injection device assembly, a driving assembly and a locking assembly, the injection device assembly comprises a syringe and a plug rod, the driving assembly comprises a driving member and a driver, the locking assembly comprises a guide member and a locking member, the guide member and the locking member lock the second end of the plug rod on the driver, the guide member is located between the second end of the plug rod and the locking member, and the two ends of the guide member are in point contact with the plug rod and the locking member respectively. Since the plug rod of the injection device assembly is connected to the driver through the locking assembly, the locking assembly comprises a guide member and a locking member, the guide member is located between the plug rod and the locking member, and the two ends of the guide member are in point contact with the plug rod and the locking member respectively, the point contact setting enables the locking member to apply an axial locking force to the plug rod without a radial force component, thereby preventing the plug rod from tilting during installation, and maintaining position accuracy after multiple uses, thereby ensuring the sample injection accuracy after multiple uses.

Description

Technical Field

[0001] The invention relates to a sample adding device, in particular to a sample analyzer and a sample adding injection device. Background Art

[0002] In a sample analyzer, a sample adding and injecting device is usually used to provide negative pressure to the dispensing needle so that the dispensing needle absorbs a sample or a reagent, or a sample adding and injecting device is used to provide positive pressure to the dispensing needle so that the dispensing needle dispenses a sample or a reagent.

[0003] The piston or plunger of the existing sample addition injection device is connected to the driving component by an axial screw. During the assembly process, the plunger rod is prone to tilt, resulting in a reduced seal life and affecting the sample addition accuracy. Summary of the invention

[0004] In one embodiment, a sample analyzer is provided, comprising:

[0005] Machine base;

[0006] The dispensing mechanism comprises a dispensing needle and a dispensing needle moving device, wherein the dispensing needle moving device is mounted on the machine base, the dispensing needle is mounted on the dispensing needle moving device, and the dispensing needle moving device is used to drive the dispensing needle to move;

[0007] and a sample adding and injecting device, the sample adding and injecting device comprising a mounting seat, an injection device assembly, a driving assembly and a locking assembly;

[0008] The mounting seat is mounted on the machine base;

[0009] The injection device assembly comprises a syringe and a plug rod, wherein the syringe is mounted on the mounting seat, the plug rod has a first end and a second end, and the first end of the plug rod is axially movably connected to the syringe; the syringe is connected to the dispensing needle through a pipeline;

[0010] The driving assembly comprises a driving member and a driver, wherein the driving member is mounted on the mounting seat, the driver is slidably mounted on the mounting seat, and the driving member is connected to the driver;

[0011] The locking assembly comprises a guide member and a locking member, wherein the guide member and the locking member lock the second end of the plug rod on the driver, the guide member is located between the second end of the plug rod and the locking member, and the two ends of the guide member are in point contact with the plug rod and the locking member respectively;

[0012] The sample addition and injection device provides positive pressure or negative pressure to the dispensing needle so that the dispensing needle can absorb or dispense samples or reagents.

[0013] In one embodiment, the guide member and the locking member are aligned in a straight line.

[0014] In one embodiment, the guide member and the locking member are aligned on the axis of the plug rod.

[0015] In one embodiment, the guide member is a spherical structure.

[0016] In one embodiment, two ends of the guide member are symmetrical hemispherical structures or conical structures.

[0017] In one embodiment, the driver has a slot at one end facing the plug rod, the second end of the plug rod is connected to the slot of the driver, and the driver has a locking hole at one end facing away from the plug rod, the locking hole extends to communicate with the slot; the guide member and the locking member are installed in the locking hole.

[0018] In one embodiment, the locking member is a locking screw, and the locking hole is provided with an internal thread adapted to the locking member.

[0019] In one embodiment, the slot is provided with a narrowing portion, and the second end of the plug rod is provided with a groove, and the narrowing portion of the slot is snapped into the groove of the plug rod; the slot is provided with an opening extending radially to the side, and the opening is used to snap into the second end of the plug rod.

[0020] In one embodiment, the driver is slidably connected to the mounting seat via a guide rail, and the guide rail is arranged parallel to the plug rod.

[0021] In one embodiment, the guide rail is a cross roller guide rail.

[0022] In one embodiment, a spring is provided on the mounting seat, one end of the spring is connected to the mounting seat, and the other end of the spring is connected to the driver, and the spring is always in a stretched state.

[0023] In one embodiment, the sample addition and injection device also includes a transmission assembly, which includes a reduction gear group and a gear rack group, the reduction gear group includes a first reduction gear and a second reduction gear, the gear rack group includes a transmission gear and a rack, the first reduction gear is connected to the output shaft of the driving member, a transmission shaft is installed on the mounting seat, the second reduction gear and the transmission gear are respectively fixedly installed on the transmission shaft, the second reduction gear is meshed with the first reduction gear, the rack is installed on the driver, and the rack is meshed with the transmission gear.

[0024] In one embodiment, the sample addition and injection device also includes a transmission assembly, which includes a screw and a slider. The screw is rotatably mounted on the mounting seat, one end of the screw is connected to the driving member, the slider is fixedly connected to the driver, the slider is provided with a threaded hole, and the screw is connected to the threaded hole of the slider.

[0025] In one embodiment, the sample addition and injection device also includes a transmission assembly, the transmission assembly includes a screw rod, the screw rod is rotatably mounted on the mounting seat, one end of the screw rod is connected to the driving member, the driver is provided with a threaded hole, and the other end of the screw rod is connected to the threaded hole of the driver.

[0026] In one embodiment, the mounting seat is provided with a mounting portion extending radially along the syringe, the mounting portion is provided with a mounting hole along the axial direction of the syringe, and one end of the syringe close to the driver is fixed in the mounting hole of the mounting seat.

[0027] In one embodiment, a limit block and a locking nut are provided on the syringe, and the syringe is provided with an external thread connected to the locking nut. The limit block and the locking nut are located on both axial sides of the mounting portion, and the limit block and the locking nut fix the syringe on the mounting portion of the mounting seat.

[0028] In one embodiment, a sample addition injection device is provided, comprising:

[0029] Mounting seat;

[0030] An injection device assembly, comprising a syringe and a plug rod, wherein the syringe is mounted on the mounting seat, the plug rod has a first end and a second end, and the first end of the plug rod is axially movably connected in the syringe;

[0031] A driving assembly, comprising a driving member and a driver, wherein the driving member is mounted on the mounting seat, the driver is slidably mounted on the mounting seat, and the driving member is connected to the driver;

[0032] And a locking assembly, including a guide member and a locking member, wherein the guide member and the locking member lock the second end of the plug rod on the driver, the guide member is located between the second end of the plug rod and the locking member, and the two ends of the guide member are in point contact with the plug rod and the locking member respectively.

[0033] According to the sample analyzer and sample loading and injection device of the above-mentioned embodiments, since the plug rod of the injection device assembly of the sample loading and injection device is connected to the driver through the locking assembly, the locking assembly includes a guide member and a locking member, the guide member is located between the plug rod and the locking member, and the two ends of the guide member are respectively in point contact with the plug rod and the locking member, and the point contact setting enables the locking member to apply an axial locking force to the plug rod without the presence of a radial force component, thereby preventing the plug rod from tilting during the installation process, and maintaining position accuracy after multiple uses, thereby ensuring the sample loading accuracy after multiple uses. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 A schematic diagram of the structure of a sample addition analyzer in an embodiment;

[0035] Figure 2 A schematic diagram of the structure of a sample addition injection device in an embodiment;

[0036] Figure 3 A side view of a partial side section of a sample injection device in an embodiment;

[0037] Figure 4 A schematic diagram of the structure of a sample addition injection device in an embodiment;

[0038] Figure 5 An axial cross-sectional view of a driver in one embodiment;

[0039] Figure 6 A schematic diagram of the structure of a driver in an embodiment;

[0040] Figure 7 for Figure 3 Sectional view along BB;

[0041] Figure 8 A schematic diagram of the structure of a transmission assembly in an embodiment;

[0042] Fig. 9 A schematic diagram of the structure of a sample addition injection device in an embodiment;

[0043] Fig.10 A schematic diagram of the structure of a sample adding and injecting device and a sample dispensing mechanism in an embodiment;

[0044] Fig.11 It is a schematic diagram of the structure of a sample injection device and a reagent dispensing mechanism in an embodiment. DETAILED DESCRIPTION

[0045] In the sample analyzer, the sample adding and injecting device is connected to the sample adding pipeline, and the sample adding and injecting device is used to absorb the sample through the sample adding pipeline and accurately inject the sample into the reaction cup. After working for a long time, the traditional sample adding and injecting device will have the problem of reduced accuracy, resulting in inaccurate sample addition and affecting the accuracy of detection.

[0046] The applicant has found that the main reasons affecting the sampling accuracy of the sample injection device are the connection and installation of the injection device assembly and the structure of the transmission assembly. Solving any of these problems can improve the sampling accuracy of the sample injection device. In this application, the connection and installation of the injection device assembly and the structure of the transmission assembly are improved respectively to improve the sampling accuracy of the sample injection device.

[0047] The present invention is further described in detail below by specific embodiments in conjunction with the accompanying drawings. Wherein similar elements in different embodiments adopt associated similar element numbers. In the following embodiments, many detailed descriptions are for making the present application better understood. However, those skilled in the art can easily recognize that some features can be omitted in different situations, or can be replaced by other elements, materials, methods. In some cases, some operations related to the present application are not shown or described in the specification, this is to avoid the core part of the present application being overwhelmed by too much description, and for those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations according to the description in the specification and the general technical knowledge in the art.

[0048] In addition, the features, operations or characteristics described in the specification can be combined in any appropriate manner to form various implementations. At the same time, the steps or actions in the method description can also be interchanged or adjusted in a manner that is obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for the purpose of clearly describing a certain embodiment and are not meant to be a required sequence, unless otherwise specified that a certain sequence must be followed.

[0049] The serial numbers of the components in this document, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in this application, unless otherwise specified, include direct and indirect connections (couplings).

[0050] In one embodiment, a sample analyzer is provided, in which the sample aspiration and injection are driven by the sample injection device in the above embodiment.

[0051] Please refer to Figure 1The sample analyzer of one embodiment includes a base 100 and a sample component 200, a reagent component 400, a dispensing mechanism, a mixing mechanism 600, a reaction component 700 and a light measuring component 800 installed on the base 100. The dispensing mechanism includes a sample dispensing mechanism 300 and a reagent dispensing mechanism 500.

[0052] The sample component 200 is used to carry samples. In some examples, the sample component 200 may include a sample delivery module (SDM) and a front track; in other examples, the sample portion 10 may also be a sample tray, which includes a plurality of sample positions such as sample tubes, and the sample tray can dispatch samples to corresponding positions by rotating its tray structure, such as the position for the sample dispensing mechanism 300 to absorb the sample.

[0053] The sample dispensing mechanism 300 is used to absorb the sample and discharge it into the reaction cup to be loaded with the sample. For example, the sample dispensing mechanism 300 may include a sample needle 301 and a sample needle moving device 302. The sample needle 301 performs a two-dimensional or three-dimensional movement in space through the two-dimensional or three-dimensional sample needle moving device 302, so that the sample needle 301 can move to absorb the sample carried by the sample component 200, move to the reaction cup to be loaded with the sample, and discharge the sample into the reaction cup.

[0054] The reagent component 400 is used to carry the reagent. In one embodiment, the reagent component 400 may be a reagent disk, which is a disk-shaped structure with multiple positions for carrying reagent containers. The reagent component 400 can rotate and drive the reagent container it carries to rotate, and is used to rotate the reagent container to a specific position, such as a position where the reagent is sucked by the reagent dispensing mechanism 500. The number of the reagent components 400 may be one or more.

[0055] The reagent dispensing mechanism 500 is used to absorb the reagent and discharge it into the reaction cup to be added with the reagent. In one embodiment, the reagent dispensing mechanism 500 may include a reagent needle 501 and a reagent needle moving device 502. The reagent needle 501 performs two-dimensional or three-dimensional movement in space through the two-dimensional or three-dimensional reagent needle moving device 502, so that the reagent needle 501 can move to absorb the reagent carried by the reagent component 400, move to the reaction cup to be added with the reagent, and discharge the reagent into the reaction cup.

[0056] The mixing mechanism 600 is used to mix the reaction solution in the reaction cup. The number of the mixing mechanism 600 can be one or more.

[0057] The reaction component 700 has at least one placement position, and the placement position is used to place a reaction cup and incubate the reaction liquid in the reaction cup. For example, the reaction component 700 can be a reaction disk, which is arranged in a disk-shaped structure and has one or more placement positions for placing reaction cups. The reaction disk can rotate and drive the reaction cups in its placement positions to rotate, and is used to arrange the reaction cups in the reaction disk and incubate the reaction liquid in the reaction cups.

[0058] The light measuring component 800 is used to perform light measurement on the reaction solution after incubation to obtain the reaction data of the sample. For example, the light measuring component 800 detects the luminous intensity of the reaction solution to be measured, and calculates the concentration of the component to be measured in the sample through the calibration curve. In one embodiment, the light measuring component 800 is separately arranged outside the reaction component 700.

[0059] The sample needle 301 and the reagent needle 501 are dispensing needles with different functions. The sample needle 301 is used to suck and discharge samples, and the reagent needle 501 is used to suck and discharge reagents. The sample needle moving device 302 and the reagent needle moving device 502 are dispensing needle moving devices of different dispensing needles. The sample needle moving device 302 is used to drive the sample needle 301 to move, and the reagent needle moving device 502 is used to drive the reagent needle 501 to move.

[0060] In this embodiment, a sample injection device 900 is also provided on the base 100. The sample injection device 900 serves as a driving member. The sample injection device 900 is connected to the sample needle 301. The sample injection device 900 is used to provide negative pressure or positive pressure to the sample needle 301 to drive the sample needle 301 to absorb and discharge the sample. In some embodiments, the sample injection device 900 is connected to the reagent needle 501. The sample injection device 900 is used to provide negative pressure or positive pressure to the reagent needle 501 to drive the reagent needle 501 to absorb and discharge the reagent.

[0061] Please refer to Figure 2 and Figure 3 In this embodiment, the sample addition injection device mainly includes a mounting seat 10, an injection device assembly 20, a drive assembly 30, a locking assembly 40 and a transmission assembly 50. Among them, the mounting seat 10 is a supporting component of the entire sample addition injection device, and the mounting seat 10 is spliced ​​by a plurality of metal plates. The injection device assembly 20 is also called a syringe body. The injection device assembly 20 is any one of a piston syringe and a plunger syringe. The injection device assembly 20 includes a syringe 21 and a plug rod 22. The syringe 21 is mounted on the mounting seat 10, and the plug rod 22 is mounted in the syringe 21. The drive assembly 30 includes a drive member 31 and a driver 32. The drive member 31 is fixedly mounted on the mounting seat 10, and the driver 32 is movably mounted on the mounting seat 10. The end of the plug rod 22 exposed from the syringe 21 is connected to the driver 32 through the locking assembly 40. The transmission assembly 50 is mounted on the mounting seat 10, and the drive member 31 is connected to the driver 32 through the transmission assembly 50.

[0062] The working principle of the sample adding and injection device is as follows: the driving member 31 drives the driver 32 to move linearly and reciprocatingly through the transmission assembly 50, and the driver 32 drives the plug rod 22 to move linearly and reciprocatingly, thereby driving the sample adding and injection device to form negative pressure or positive pressure.

[0063] In this embodiment, the mounting seat 10 includes a mounting plate 11 and a mounting bracket 12. The injection device assembly 20 and the driving assembly 30 are respectively mounted on both sides of the mounting plate 11. The syringe 21 of the injection device assembly 20 is directly mounted on one side of the mounting plate 11. The mounting bracket 12 is mounted on the side of the mounting plate 11 facing away from the injection device assembly 20. The driving member 31 is mounted on the mounting bracket 12. The mounting plate 11 is provided with an avoidance hole 13 parallel to the plug rod 22. The avoidance hole 13 is a strip-shaped structure. The driver 32 is a slider. The driver 32 can be linearly slidably mounted on the mounting plate 11 through a guide rail 33. The guide rail 33 is arranged parallel to the plug rod 22. The driver 32, the guide rail 33 and the plug rod 22 are located on the same side of the mounting plate 11.

[0064] A housing 14 is also mounted on the mounting base 10 , and the housing 14 is mounted on the mounting plate 11 . The housing 14 covers the mounting bracket 12 , the driving assembly 30 and the transmission assembly 50 , so as to prevent the driving assembly 30 and the transmission assembly 50 from being disturbed by the outside world.

[0065] In this embodiment, the two ends of the plug rod 22 are respectively defined as a first end and a second end. The first end of the plug rod 22 is connected to the syringe 21. The first end of the plug rod 22 can move axially in the syringe 21. The second end of the plug rod 22 is exposed from the syringe 21. The second end of the plug rod 22 is exposed from the syringe 21 and is connected to the driver 32 through the locking assembly 40.

[0066] Please refer to Figure 4 , Figure 5 and Figure 6 The locking assembly 40 includes a guide member 41 and a locking member 42. The guide member 41 is preferably a guide steel ball. The guide member 41 can also be a hemispherical or conical structure at both ends. The middle part between the hemispherical or conical structures at both ends is a cylindrical or tubular structure. Both ends of the guide member 41 are contact points; the locking member 42 is a locking screw.

[0067] The driver 32 is provided with a slot 321 and a locking hole 322. The slot 321 is arranged toward the plug rod 22, and the slot 321 is narrowed to form a narrowing portion. The second end of the plug rod 22 is provided with an annular groove 221 adapted to the slot 321. The second end of the plug rod 22 is inserted into the slot 321, and the narrowing portion of the slot 321 is clamped in the annular groove 221 of the plug rod 22, so that the narrowing portion can limit the axial freedom of the plug rod 22.

[0068] The guide rail 33 preferably adopts a cross roller guide rail, which has the advantages of small resistance, high precision and strong stability, and can ensure the accuracy of the linear movement of the driver 32.

[0069] In order to enable the plug rod 22 to be installed and removed from the slot 321 of the driver 32, an opening is provided on an axial side of the slot 321, and the second end of the plug rod 22 can be radially inserted or removed from the side opening of the slot 321. The axial width of the annular groove 221 of the plug rod 22 is greater than the axial thickness of the narrowed portion of the slot 321, so that the plug rod 22 can be easily inserted and removed from the slot 321.

[0070] In other embodiments, a flange structure is provided at the second end of the plug rod 22 , that is, the second end of the plug rod 22 is a T-shaped structure, which can also achieve the limited installation of the plug rod 22 .

[0071] In this embodiment, the locking assembly 40 cooperates with the narrowing portion of the slot 321 to jointly limit the axial freedom of the second end of the plug rod 22. The locking hole 322 of the driver 32 and the slot 321 are arranged on the axis of the plug rod 22, the locking hole 322 is located on the other side of the slot 321, and the locking hole 322 is connected with the slot 321. The locking hole 322 is provided with a receiving cavity at one end close to the slot 321, and the receiving cavity is larger than the volume of the guide member 41 (guide steel ball), and the guide member 41 can be installed in the receiving cavity of the locking hole 322, and the locking hole 322 is provided with a threaded hole at one end away from the slot 321, and the locking member 42 (locking screw) is installed in the threaded hole of the locking hole 322. The end of the locking member 42 located in the threaded hole abuts against one end of the guide member 41, and the other end of the guide member 41 abuts against the end face of the second end of the plug rod 22. The axial locking force provided by the guide member 41 is applied to the second end of the plug rod 22 by point contact, thereby locking the plug rod 22 on the driver 32.

[0072] The accommodating cavity of the locking hole 322 has an inner diameter adapted to the guide member 41, and is used to limit the radial position of the guide member 41, so that the guide member 41 and the locking member 42 are aligned on a straight line, especially the guide member 41 and the locking member 42 are aligned on the axis of the plug rod 22, so as to avoid the generation of radial force components, thereby avoiding the inclination of the plug rod 22, so as to improve the stability of the plug rod 22. In some embodiments, the guide member 41 and the locking member 42 are aligned on a straight line, and the straight line is parallel to the axis of the plug rod 22, which can also avoid the generation of radial force components and also improve the stability of the plug rod 22.

[0073] In some embodiments, the accommodating cavity of the locking hole 322 may also be classified as a part of the card slot 321, or as a part independent of the locking hole 322 and the card slot 321, and the accommodating cavity is connected to the locking hole 322 and the card slot 321 respectively.

[0074] In this embodiment, since the plug rod 22 of the injection device assembly 20 is connected to the driver 32 through the locking assembly 40, the locking assembly 40 includes a guide member 41 and a locking member 42. The guide member 41 is a guide steel ball, and the locking member 42 is a locking screw. The guide steel ball is located between the plug rod 22 and the locking screw, and the two ends of the guide steel ball are respectively in point contact with the plug rod 22 and the locking screw. The point contact setting enables the locking screw to apply an axial locking force to the plug rod 22 without a radial force component, thereby preventing the plug rod 22 from tilting during the installation process. After multiple uses, the position accuracy can still be maintained, thereby ensuring the sample addition accuracy after multiple uses.

[0075] Please refer to Figure 7 and Figure 8 In this embodiment, the transmission assembly 50 is a two-stage transmission structure. The transmission assembly 50 is mounted on the mounting plate 11 and is located in the housing 14. The transmission assembly 50 includes a reduction gear set 51 and a gear rack set 52. The reduction gear set 51 is a first-stage transmission component, and the gear rack set 52 is a second-stage transmission component. The reduction gear set 51 is used to reduce speed and increase distance, and the gear rack set 52 is used to convert rotary drive into linear drive.

[0076] The driving member 31 is a motor, and the reduction gear set 51 includes a first reduction gear 511 and a second reduction gear 512. The first reduction gear 511 is a small gear, and the second reduction gear 512 is a large gear. The first reduction gear 511 and the second reduction gear 512 are meshed and connected, and there is a preset transmission ratio between the first reduction gear 511 and the second reduction gear 512, such as a transmission ratio of 0.1. The first reduction gear 511 is installed on the output shaft of the driving member 31, and the second reduction gear 512 is fixedly installed on the transmission shaft 53, and the transmission shaft 53 is rotatably installed on the mounting bracket 12 through a bearing.

[0077] The gear rack set 52 includes a gear 521 and a rack 522. The gear 521 is fixedly mounted on the transmission shaft 53. The gear 521 rotates synchronously with the second reduction gear 512. The rack 522 is connected to the driver 32, and the rack 522 is also meshed with the gear 521.

[0078] The transmission principle of the transmission assembly 50 is: the driving member 31 drives the first reduction gear 511 to rotate, the first reduction gear 511 drives the second reduction gear 512 to rotate, the second reduction gear 512 outputs a lower rotation speed than the first reduction gear 511, the second reduction gear 512 rotates synchronously with the gear 521 through the transmission shaft 53, the gear 521 drives the rack 522 to move linearly, and then the rack 522 drives the driver 32 to move linearly.

[0079] In this embodiment, the transmission assembly 50 adopts a two-stage gear transmission, and a transmission chain is formed by the combination of a reduction gear group 51 and a gear rack group 52. The reduction gear group 51 can play a role of reducing speed and increasing distance, so that the driving member 31 can reciprocate the plug rod 22 through a smaller driving force, which can ensure the driving accuracy of the driving member 31, thereby ensuring the accuracy of the plug rod 22 during long-term movement, and further ensuring the sampling accuracy.

[0080] Please refer to Figure 4 In this embodiment, a spring 15 is also installed on the mounting seat 10, a mounting column 16 is provided on the surface of the mounting plate 11 facing away from the injection device assembly 20, and a mounting column 34 is also provided on the end of the driver 32 passing through the avoidance hole 13. The mounting column 16 and the mounting column 34 are aligned and installed on the center line of the length direction of the avoidance hole 13, or the connecting line between the mounting column 16 and the mounting column 34 is parallel to the moving direction of the driver 32. The two ends of the spring 15 are respectively connected to the mounting column 16 and the mounting column 34. The spring 15 is always in a stretched state. The spring 15 is used to provide a pre-tightening force for the driver 32. The spring 15 can eliminate the gap generated during the transmission process between the first reduction gear 511 and the second reduction gear 512, and can eliminate the gap generated during the transmission process between the gear 521 and the rack 522, thereby ensuring the transmission accuracy between the first reduction gear 511 and the second reduction gear 512 and between the gear 521 and the rack 522.

[0081] In one embodiment, the transmission assembly 50 of the sample loading and injection device includes a screw and a nut, the screw is mounted on the mounting seat 10 through a bearing, one end of the screw is connected to the driving member 31, the nut is connected to the screw, the nut is connected to the driver 32, and the driving member 31 can drive the driver 32 to move linearly and reciprocatingly through the screw and the nut. In the sample loading and injection device, since the locking assembly 40 is provided, the locking assembly 40 can axially lock the plug rod, improve the stability of the plug rod, and thus the sample loading and injection device still has higher sample loading accuracy and stability than the traditional device.

[0082] In one embodiment, the driving member 31 of the sample loading and injection device is a cylinder or a linear motor, and the above-mentioned transmission assembly 50 is not provided. The output end of the driving member 31 is directly connected to the driver 32, and the driving member 31 directly drives the linear reciprocating movement of the driver 32. In the sample loading and injection device, since the locking assembly 40 is provided, the locking assembly 40 can axially lock the plug rod, improve the stability of the plug rod, and thus the sample loading and injection device still has higher sample loading accuracy and stability than the traditional device.

[0083] In one embodiment, the locking assembly 40 is replaced with a conventional locking device. Since a transmission assembly 50 is provided in the sample loading and injection device, the transmission assembly 50 has the function of reducing speed and increasing distance, thereby reducing the driving torque of the driving member 31 and improving the output stability of the driving member 31, so that the sample loading and injection device still has higher sample loading accuracy and stability than conventional devices.

[0084] Please refer to Fig. 9 In this embodiment, a protruding mounting portion 111 is provided on the mounting plate 11. The mounting portion 111 is a plate-shaped structure and is provided with a mounting hole.

[0085] The two ends of the syringe 21 are defined as a first end and a second end. The first end of the syringe 21 is connected to the sample needle 301 through a pipeline, and the second end of the syringe 21 is inserted into the mounting hole of the mounting portion 111. A limit block 211 and a locking nut 212 are installed on the second end of the syringe 21. The limit block 211 is fixed to the syringe 21 by threaded connection or clamping. The limit block 211 and the syringe 21 can also be an integrated structure. The end of the second end of the limit block 211 is provided with an external thread, and the locking nut 212 is installed on the syringe 21 by threaded connection. The limit block 211 and the locking nut 212 are respectively located on both sides of the mounting portion 111. Under the locking force of the locking nut 212, the limit block 211 and the locking nut 212 lock the syringe 21 on the mounting portion 111 of the mounting plate 11.

[0086] In this embodiment, since the stopper rod 22 is connected to the second end of the syringe 21, the second end of the syringe 21 is more likely to shake relative to the first end during the movement of the stopper rod 22. Therefore, the second end of the syringe 21 is locked on the mounting portion 111 through the axial locking nut 212, which can ensure the stability of the syringe 21, thereby ensuring the accuracy of the movement of the stopper rod 22 and the accuracy of sample addition.

[0087] Please refer to Fig.10 In this embodiment, the sample adding and injection device 900 is connected to the sample dispensing mechanism 300, wherein the mounting seat 10 is installed on the machine base 100, and the sample needle 301 is connected to the syringe 21 through a pipeline. The sample adding and injection device 900 provides positive pressure and negative pressure drive for the sample needle 301 to realize sample spitting and sample aspiration of the sample needle 301.

[0088] In the sample loading and injection device 900 , at least one of the installation of the syringe 21 , the installation of the stopper rod 22 and the transmission assembly 50 is improved. Compared with the traditional sample loading and injection device, the sample loading and injection device 900 can ensure the loading accuracy of the sample dispensing mechanism 300 .

[0089] Please refer to Fig.11In one embodiment, the sample adding and injection device 900 is connected to the reagent dispensing mechanism 500, wherein the mounting seat 10 is installed on the machine base 100, and the reagent needle 501 is connected to the syringe 21 through a pipeline. The sample adding and injection device 900 provides positive pressure and negative pressure drive for the reagent needle 501 to enable the reagent needle 501 to spit out and absorb the reagent.

[0090] The sample adding injection device 900 has improved at least one of the installation of the syringe 21 , the installation of the stopper rod 22 and the transmission assembly 50 . Compared with the traditional sample adding injection device, the sample adding injection device 900 can ensure the reagent adding accuracy of the reagent dispensing mechanism 500 .

[0091] The above specific examples are used to illustrate the present invention, which is only used to help understand the present invention and is not intended to limit the present invention. For those skilled in the art, according to the concept of the present invention, some simple deductions, modifications or substitutions can be made.

Claims

1. A sample analyzer, characterized in that: include Machine base; The dispensing mechanism comprises a dispensing needle and a dispensing needle moving device, wherein the dispensing needle moving device is mounted on the machine base, the dispensing needle is mounted on the dispensing needle moving device, and the dispensing needle moving device is used to drive the dispensing needle to move; and a sample adding and injecting device, the sample adding and injecting device comprising a mounting seat, an injection device assembly, a driving assembly and a locking assembly; The mounting seat is mounted on the machine base; The injection device assembly comprises a syringe and a plug rod, wherein the syringe is mounted on the mounting seat, the plug rod has a first end and a second end, and the first end of the plug rod is axially movably connected to the syringe; the syringe is connected to the dispensing needle through a pipeline; The driving assembly comprises a driving member and a driver, wherein the driving member is mounted on the mounting seat, the driver is slidably mounted on the mounting seat, and the driving member is connected to the driver; The locking assembly comprises a guide member and a locking member, wherein the guide member and the locking member lock the second end of the plug rod on the driver, the guide member is located between the second end of the plug rod and the locking member, and the two ends of the guide member are in point contact with the plug rod and the locking member respectively; The sample addition and injection device provides positive pressure or negative pressure to the dispensing needle so that the dispensing needle can absorb or dispense samples or reagents.

2. The sample analyzer according to claim 1, characterized in that: The guide member and the locking member are aligned in a straight line.

3. The sample analyzer according to claim 1, wherein: The guide member and the locking member are aligned on the axis of the plug rod.

4. The sample analyzer according to claim 1, wherein: The guide member is a spherical structure.

5. The sample analyzer according to claim 1, wherein: The two ends of the guide member are symmetrical hemispherical structures or conical structures.

6. The sample analyzer according to claim 1, wherein: The driver has a slot at one end facing the plug rod, the second end of the plug rod is connected to the slot of the driver, and the driver has a locking hole at one end facing away from the plug rod, the locking hole extends to communicate with the slot; the guide member and the locking member are installed in the locking hole.

7. The sample analyzer according to claim 6, characterized in that: The locking piece is a locking screw, and the locking hole is provided with an internal thread matched with the locking piece.

8. The sample analyzer according to claim 6, wherein: The slot is provided with a narrowing portion, the second end of the plug rod is provided with a groove, the narrowing portion of the slot is engaged in the groove of the plug rod; the slot is provided with an opening extending radially to the side, the opening is used to engage the second end of the plug rod.

9. The sample analyzer according to claim 1, wherein: The driver is slidably connected to the mounting seat via a guide rail, and the guide rail is arranged parallel to the plug rod.

10. The sample analyzer according to claim 9, characterized in that: The guide rail is a cross roller guide rail.

11. The sample analyzer according to claim 1, wherein: A spring is arranged on the mounting seat, one end of the spring is connected to the mounting seat, and the other end of the spring is connected to the driver, and the spring is always in a stretched state.

12. The sample analyzer according to any one of claims 1 to 11, characterized in that: The sample injection device also includes a transmission assembly, which includes a reduction gear group and a gear rack group, the reduction gear group includes a first reduction gear and a second reduction gear, the gear rack group includes a transmission gear and a rack, the first reduction gear is connected to the output shaft of the driving member, a transmission shaft is installed on the mounting seat, the second reduction gear and the transmission gear are respectively fixedly installed on the transmission shaft, the second reduction gear is meshed with the first reduction gear, the rack is installed on the driver, and the rack is meshed with the transmission gear.

13. The sample analyzer according to any one of claims 1 to 11, characterized in that: The sample addition and injection device also includes a transmission assembly, which includes a screw and a slider. The screw is rotatably mounted on the mounting seat, one end of the screw is connected to the driving member, the slider is fixedly connected to the driver, the slider is provided with a threaded hole, and the screw is connected to the threaded hole of the slider.

14. The sample analyzer according to any one of claims 1 to 11, characterized in that: The sample addition injection device also includes a transmission assembly, which includes a screw rod, which is rotatably mounted on the mounting seat, one end of the screw rod is connected to the driving member, the driver is provided with a threaded hole, and the other end of the screw rod is connected to the threaded hole of the driver.

15. The sample analyzer according to any one of claims 1 to 11, characterized in that: The mounting seat is provided with a mounting portion extending radially along the syringe, the mounting portion is provided with a mounting hole along the axial direction of the syringe, and one end of the syringe close to the driver is fixed in the mounting hole of the mounting seat.

16. The sample analyzer according to claim 15, characterized in that: The syringe is provided with a limit block and a locking nut, the syringe is provided with an external thread connected to the locking nut, the limit block and the locking nut are located on both axial sides of the mounting portion, and the limit block and the locking nut fix the syringe on the mounting portion of the mounting seat.

17. A sample injection device, characterized in that: include: Mounting seat; An injection device assembly, comprising a syringe and a plug rod, wherein the syringe is mounted on the mounting seat, the plug rod has a first end and a second end, and the first end of the plug rod is axially movably connected in the syringe; A driving assembly, comprising a driving member and a driver, wherein the driving member is mounted on the mounting seat, the driver is slidably mounted on the mounting seat, and the driving member is connected to the driver; And a locking assembly, including a guide member and a locking member, wherein the guide member and the locking member lock the second end of the plug rod on the driver, the guide member is located between the second end of the plug rod and the locking member, and the two ends of the guide member are in point contact with the plug rod and the locking member respectively.

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