A slide staining and drying integrated device

Abstract

The present invention relates to an integrated device for slide staining and drying, which includes a staining module and a drying module. A slide transfer assembly for turnover is provided between the staining module and the drying module; the staining module includes an X-axis movement mechanism, a Y-axis movement mechanism, a staining housing, a staining top cover, a staining nozzle mechanism and a lower nozzle assembly. The X-axis movement mechanism is installed above the staining top cover, and the X-axis movement mechanism is connected to the staining nozzle mechanism. The staining nozzle mechanism is located inside the staining housing and above the lower nozzle assembly. Both the lower nozzle assembly and the Y-axis movement mechanism are installed on the staining housing; the slide transfer assembly includes a bracket assembly, a slide transfer rack and a clamping mechanism. The bracket assembly is connected to the Y-axis movement mechanism. The bracket assembly can detachably place the slide transfer rack, and the clamping mechanism is installed on the slide transfer rack; one set of drying module is provided. The present invention has the advantages of small volume, few movement mechanisms, low failure rate, short drying time and high slide preparation efficiency for stained slides.

Description

Technical Field

[0001] The present invention relates to the technical field of medical testing, and particularly relates to an integrated device for slide staining and drying. Background Art

[0002] In microscopic examination imaging, the preparation efficiency of stained slides becomes a key factor restricting the examination efficiency. The production of conventional stained slides includes the drying of samples, the staining of samples, and the re-drying after staining. The invention patent "Slide Sampling, Staining, and Sampling Device and Automatic Slide Staining Device" (Chinese Patent Publication No. CN209589628U) provides a slide sampling, staining, and sampling device and an automatic slide staining device. The automatic slide staining device includes a slide sampling device, a slide staining device, and a slide sampling device. This automatic slide staining device can realize the automatic sampling, staining, and sampling of slides, improving the staining efficiency of slides. However, there are the following problems: First, there are relatively many moving mechanisms, resulting in a high failure rate. And two sets of drying components are used, one for drying the samples in the front-end slide sampling device and the other for re-drying after staining in the back-end slide sampling device. And only one or two slides can be dried at a time, resulting in a low preparation efficiency of stained slides, thus restricting the examination efficiency. Second, the middle-end slide staining device adopts a conventional centrifugal structure, and there are the following problems: If the centrifugal speed is slow, there will be liquid residues. In addition to the residual staining solution above the slide, there will also be residual staining solution on the back of the slide, which will form interference in microscopic examination. If the centrifugal speed is fast, some staining solution will be thrown out, and the quality of the produced stained slides is poor, thus restricting the examination efficiency and affecting the examination results. Therefore, it is particularly important to develop an integrated device for slide staining and drying with a small volume, few moving mechanisms, low failure rate, short drying time, high preparation quality of stained slides, and high preparation efficiency. Summary of the Invention

[0003] The technical problem to be solved by the present invention is to overcome the above-mentioned defects of the prior art and provide an integrated device for slide staining and drying. The integrated device for slide staining and drying has a small volume, few moving mechanisms, low failure rate, short drying time, and relatively high preparation efficiency of stained slides.

[0004] The present invention is realized by the following technical solutions:

[0005] An integrated device for slide staining and drying includes a staining module and a drying module, and a slide transfer assembly for turnover is provided between the staining module and the drying module;

[0006] The dyeing module includes an X-axis motion mechanism, a Y-axis motion mechanism, a dyeing housing, a dyeing top cover, a dyeing nozzle mechanism, and a lower nozzle assembly. The X-axis motion mechanism is installed above the dyeing top cover and is connected to the dyeing nozzle mechanism. The dyeing nozzle mechanism is located inside the dyeing housing and above the lower nozzle assembly. Both the lower nozzle assembly and the Y-axis motion mechanism are installed on the dyeing housing;

[0007] The glass slide transfer assembly includes a bracket assembly, a glass slide transfer rack, and a clamping mechanism. The bracket assembly is connected to the Y-axis motion mechanism. The bracket assembly can detachably place the glass slide transfer rack. The clamping mechanism is installed on the glass slide transfer rack;

[0008] There is one set of drying module.

[0009] As an optimization, the bracket assembly includes a bracket body, a bracket connecting piece, and a first magnet. The bracket body is connected to the Y-axis motion mechanism through the bracket connecting piece. The first magnet is installed on the bracket body.

[0010] As an optimization, the glass slide transfer rack is used to carry a number of glass slides. Each glass slide is automatically inserted by a manipulator onto the corresponding clamping mechanism on the glass slide transfer rack.

[0011] Each clamping mechanism includes a clamping support, a spring piece, and a locking screw. The clamping support and the glass slide transfer rack are integrally formed. The spring piece is installed on the clamping support through the locking screw. A second magnet is installed on the clamping support.

[0012] As an optimization, the X-axis motion mechanism is a gear-rack motion mechanism, which includes an X-axis motor, a motor mounting plate, Gear I, Rack I, and a guide rail slider. The motor mounting plate is installed above the dyeing housing. The X-axis motor is installed on the motor mounting plate. Gear I is connected to the motor shaft and meshes with Rack I. The guide rail slider is arranged in parallel with Rack I.

[0013] As an optimization, the dyeing nozzle mechanism includes a nozzle support, a dye solution nozzle with a joint, a water joint I, an air joint I, a water nozzle, and an air nozzle. The nozzle support is connected to the motor mounting plate through a nozzle connecting frame. The dye solution nozzle with a joint, the water joint I, the air joint I, the water nozzle, and the air nozzle are all installed on the nozzle support.

[0014] As an optimization, the Y-axis movement mechanism is a nut-screw movement mechanism, which includes a Y-axis motor, a driving gear, a driven gear, a screw rod, a guide rail, a nut-guide rail connecting block, a guide rail slider, a linear bearing, a Y-axis bracket, and a guide shaft bracket. The Y-axis motor is installed above the dyeing top cover, the driving gear is installed on the motor shaft of the Y-axis motor, the driven gear is installed on the screw rod, the driven gear meshes with the driving gear, the slider is installed on the guide rail, the upper end of the nut-guide rail connecting block is installed on the screw rod through a nut, and the lower end is installed on the guide rail through the slider. The screw rod is installed on the Y-axis bracket through the guide shaft bracket. The Y-axis bracket connects the screw rod and the guide rail, and the nut-guide rail connecting block is connected to the bracket assembly.

[0015] As an optimization, the drying module includes a Z-axis lifting mechanism, a drying bracket assembly, and a heating assembly. The Z-axis lifting mechanism is connected to the drying bracket assembly, and the heating assembly is located in front of the drying bracket assembly.

[0016] As an optimization, the Z-axis lifting mechanism includes a stepper motor, a motor connecting frame, Gear II, Rack II, a guide rail fixing frame, a guide rail, and a slider. The stepper motor is installed on the motor connecting frame, Gear II is installed on the motor shaft of the stepper motor, Gear II meshes with Rack II, Rack II is installed on one side of the guide rail fixing frame, the guide rail is installed on the other side of the guide rail fixing frame, the slider is installed on the guide rail, and the slider is connected to the motor connecting frame.

[0017] As an optimization, the drying bracket assembly includes three drying brackets arranged vertically and horizontally, a drying bracket back plate, a drying bottom plate, and a bracket rib plate. The three drying brackets are installed on the drying bracket back plate, the drying bracket back plate is connected to the motor connecting frame, the guide rail fixing frame is installed on the drying bottom plate, and the bracket rib plate connects the guide rail fixing frame and the drying bottom plate.

[0018] As an optimization, the heating assembly includes a PTC heater, a fan, and a fan bracket. The PTC heater is erected and perpendicular to the drying bracket, the fan is located in front of the PTC heater and parallel to the PTC heater, and the fan is installed on the fan bracket.

[0019] As an optimization, a waterproof baffle is provided between the Y-axis movement mechanism and the dyeing nozzle mechanism.

[0020] The beneficial effects of the present invention are:

[0021] The present invention is scientifically designed, ingeniously conceived, small in size, with few moving mechanisms, low failure rate, short drying time, and relatively high slide preparation efficiency for stained slides. By adding a slide transfer component, it integrates functions such as sample positioning, sample loading, sample drying, and re-drying after staining. The slide transfer rack can be quickly rotated between the staining module and the drying module through the Y-axis moving mechanism, and only one set of drying module is required to dry multiple slides at a time. Compared with the prior art that uses two sets of drying components and can only dry one or two slides at a time, it has a smaller volume, fewer moving mechanisms, lower failure rate, and shorter drying time, thus effectively improving the slide preparation efficiency for stained slides. In addition, the X-axis moving mechanism in the staining module facilitates the staining, air jetting, and water spraying operations of the staining nozzle mechanism on the slides; through the effective cooperation of the staining nozzle mechanism and the lower nozzle component in the staining module, it is convenient to wash and blow the residual liquid above and on the back of the slides, resulting in higher-quality stained slides. At the same time, it effectively avoids the interference of microscope inspection caused by the back of the stained slide being contaminated with staining solution during the staining process, thereby effectively improving the inspection efficiency. It has good practical application value and promotion value. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The following further describes an integrated device for slide staining and drying with reference to the drawings:

[0023] Figure 1 is a schematic structural diagram of an integrated device for slide staining and drying;

[0024] Figure 2 is a schematic structural diagram of the staining module of an integrated device for slide staining and drying;

[0025] Figure 3 is a schematic structural diagram of the staining module of an integrated device for slide staining and drying with the staining top cover removed;

[0026] Figure 4 is a schematic structural diagram of the bracket assembly of an integrated device for slide staining and drying;

[0027] Figure 5 is a schematic structural diagram of the slide transfer rack of an integrated device for slide staining and drying;

[0028] Figure 6 is an exploded structural diagram of the X-axis moving mechanism and the staining nozzle mechanism in the staining module of an integrated device for slide staining and drying;

[0029] Figure 7 is a schematic structural diagram of the lower nozzle component in the staining module of an integrated device for slide staining and drying;

[0030] Figure 8It is a schematic structural diagram when the lower nozzle assembly in the staining module of a slide staining and drying integrated device sprays water or air onto the back of the slide;

[0031] Figure 9 It is a schematic structural diagram when removing the slide transfer assembly when the lower nozzle assembly in the staining module of a slide staining and drying integrated device sprays water or air onto the back of the slide;

[0032] Figure 10 It is a schematic exploded view of the Y-axis motion mechanism in the staining module of a slide staining and drying integrated device;

[0033] Figure 11 It is a schematic structural diagram of the drying module of a slide staining and drying integrated device;

[0034] Figure 12 It is a schematic exploded view of the initial state of the drying module of a slide staining and drying integrated device;

[0035] Figure 13 It is a schematic exploded view of the drying state of the drying module of a slide staining and drying integrated device.

[0036] In the figure: 1 is the dyeing module, 1.1 is the dyeing bracket, 1.2 is the dyeing housing, 1.3 is the X-axis movement mechanism, 1.3.1 is the X-axis motor, 1.3.2 is the motor mounting plate, 1.3.3 is Gear I, 1.3.4 is Rack I, 1.3.5 is the guide rail slider, 1.3.6 is Photoelectric Switch I, 1.3.7 is the photoelectric induction sheet I, 1.4 is the dyeing nozzle mechanism, 1.4.1 is the nozzle bracket, 1.4.2 is the dye solution nozzle, 1.4.3 is the water joint I, 1.4.4 is the air joint I, 1.4.5 is the water nozzle, 1.4.6 is the air nozzle, 1.5 is the lower nozzle assembly, 1.5.1 is the joint mounting plate, 1.5.2 is the air joint II, 1.5.3 is the air nozzle, 1.5.4 is the pure water nozzle, 1.5.5 is the water joint II, 1.6 is the dyeing top cover, 1.7 is the Y-axis movement mechanism, 1.7.1 is the Y-axis motor, 1.7.2 is the driving gear, 1.7.3 is the driven gear, 1.7.4 is the lead screw, 1.7.5 is the guide rail, 1.7.6 is the nut guide rail connection block, 1.7.7 is the slider, 1.7.8 is the linear bearing, 1.7.9 is the Y-axis bracket, 1.7.10 is the guide shaft bracket, 1.7.11 is the photoelectric induction sheet II, 1.7.12 is the photoelectric switch bracket, 1.7.13 is the photoelectric switch II, 1.8 is the waterproof baffle, 2 is the drying module, 2.1 is the Z-axis lifting mechanism, 2.1.1 is the stepper motor, 2.1.2 is the motor connecting frame, 2.1.3 is Gear II, 2.1.4 is Rack II, 2.1.5 is the guide rail fixing frame, 2.1.6 is the guide rail, 2.1.7 is the slider, 2.1.8 is the photoelectric induction sheet III, 2.1.9 is the photoelectric switch III, 2.2 is the drying bracket assembly, 2.2.1 is the drying bottom plate, 2.2.2 is the drying bracket, 2.2.3 is the drying bracket back plate, 2.2.4 is the bracket rib plate, 2.3 is the heating assembly, 2.3.1 is the PTC heater, 2.3.2 is the fan, 2.3.3 is the fan bracket, 3 is the glass slide transfer assembly, 3.1 is the glass slide transfer rack, 3.1.1 is the second magnet, 3.2 is the bracket assembly, 3.2.1 is the bracket body, 3.2.2 is the bracket connecting piece, 3.2.3 is the first magnet, 3.3 is the clamping mechanism, 3.3.1 is the clamping support, 3.3.2 is the spring piece, 3.3.3 is the locking screw, 4 is the glass slide. Detailed implementation manners

[0037] In order to enable those skilled in the art to better understand the technical solutions in the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0038] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "front", "rear", "upper", "lower", "bottom", "top", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on the present invention.

[0039] As Figures 1 - 3 shown, a slide staining and drying integrated device includes a staining module 1, a drying module 2, and a slide transfer assembly 3. The slide transfer assembly 3 circulates between the staining module 1 and the drying module 2.

[0040] The staining module 1 includes an X-axis movement mechanism 1.3, a Y-axis movement mechanism 1.7, a staining housing 1.2, a staining top cover 1.6, a staining nozzle mechanism 1.4, and a lower nozzle assembly 1.5. The X-axis movement mechanism 1.3 is installed above the staining top cover 1.6. The X-axis movement mechanism 1.3 is connected to the staining nozzle mechanism 1.4. The staining nozzle mechanism 1.4 is located inside the staining housing 1.2 and above the lower nozzle assembly 1.5. Both the lower nozzle assembly 1.5 and the Y-axis movement mechanism 1.7 are installed on the staining housing 1.2.

[0041] The slide transfer assembly 3 includes a bracket assembly 3.2, a slide transfer rack 3.1, and a clamping mechanism 3.3. The bracket assembly 3.2 is connected to the Y-axis movement mechanism 1.7. The bracket assembly 3.2 can detachably place the slide transfer rack 3.1. The clamping mechanism 3.3 is installed on the slide transfer rack 3.1.

[0042] One set of drying modules 2 is provided.

[0043] With such a design, by adding a slide transfer assembly, it integrates sample positioning, sample loading, sample drying, and re-drying after staining. The Y-axis movement mechanism is used to quickly circulate the slide transfer rack between the staining module and the drying module. And only one set of drying modules is required to dry multiple slides at a time. Compared with the prior art that uses two sets of drying components and can only dry one or two slides at a time, it has a smaller volume, fewer moving mechanisms, lower failure rates, and shorter drying times, thus effectively improving the slide preparation efficiency of stained slides. In addition, the setting of the X-axis movement mechanism in the staining module facilitates the staining nozzle mechanism to perform staining, air jetting, and water spraying operations on the slides. Through the effective cooperation of the staining nozzle mechanism and the lower nozzle assembly in the staining module, it is convenient to rinse and blow the residual liquid above and on the back of the slides, and the quality of the stained slides produced is relatively high. At the same time, it effectively avoids the interference of microscope examination caused by the back of the stained slide being contaminated with staining solution during the staining process, thereby effectively improving the examination efficiency.

[0044] As Figure 4 、Figure 5 , Figure 10 As shown in Figure 10 , the bracket assembly 3.2 includes a bracket body 3.2.1, a bracket connecting member 3.2.2, and a first magnet 3.2.3. The bracket body 3.2.1 is connected to the nut guide block 1.7.6 through the bracket connecting member 3.2.2, and the first magnet 3.2.3 is installed on the bracket body 3.2.1. The slide carrier transfer rack 3.1 is used to carry 4 slide carriers 4, and each slide carrier 4 is automatically inserted into the corresponding clamping mechanism 3.3 on the slide carrier transfer rack 3.1 by a manipulator. Each clamping mechanism 3.3 includes a clamping support 3.3.1, a spring piece 3.3.2, and a locking screw 3.3.3. The clamping support 3.3.1 and the slide carrier transfer rack 3.1 are integrally formed. The spring piece 3.3.2 is installed on the clamping support 3.3.1 through the locking screw 3.3.3, and a second magnet 3.1.1 is installed on the clamping support 3.3.1. The first magnet 3.2.3 and the second magnet 3.1.1 are movably connected by magnetic attraction. With such a design, first, the slide carriers can be automatically inserted into the clamping mechanism by a manipulator, realizing automated operation, effectively improving work efficiency, reducing contamination, and when the slide carriers are automatically inserted and contact the clamping support, they are automatically and firmly clamped by the elastic force of the spring piece, and the slide carriers will not float even under the blowing pressure of water or gas. Second, the slide carrier transfer rack and the bracket assembly are movably connected by magnetism, with a simple structure and low cost. Third, it is convenient for processing and installation, and has a good use effect.

[0045] As Figure 6 shown in Figure 6 , the X-axis movement mechanism 1.3 is a rack and pinion movement mechanism, which includes an X-axis motor 1.3.1, a motor mounting plate 1.3.2, a gear I 1.3.3, a rack I 1.3.4, and a guide rail slider 1.3.5. The motor mounting plate 1.3.2 is installed above the staining housing 1.2, the X-axis motor 1.3.1 is installed on the motor mounting plate 1.3.2, the gear I 1.3.3 is connected to the motor shaft and meshes with the rack I 1.3.4, and the guide rail slider 1.3.5 is arranged in parallel with the rack I 1.3.4. The staining nozzle mechanism 1.4 includes a nozzle support 1.4.1, a dye solution nozzle 1.4.2 with a connector, a water connector I 1.4.3, a gas connector I 1.4.4, a water nozzle 1.4.5, and a gas nozzle 1.4.6. The nozzle support 1.4.1 is connected to the motor mounting plate 1.3.2 through a nozzle connecting frame, and the dye solution nozzle 1.4.2 with a connector, the water connector I 1.4.3, the gas connector I 1.4.4, the water nozzle 1.4.5, and the gas nozzle 1.4.6 are all installed on the nozzle support 1.4.1. With such a design, it is convenient for processing and installation, has a reasonable layout, and has a good use effect.

[0046] As Figure 6As shown in the figure, it further includes a photoelectric induction sheet I 1.3.7 and a photoelectric switch I 1.3.6. The photoelectric induction sheet I 1.3.7 is installed on the motor mounting plate 1.3.2 and is located below the X-axis motor 1.3.1, and the photoelectric switch I 1.3.6 is located behind the photoelectric induction sheet 1.3.7. With such a design, the control accuracy is effectively improved.

[0047] As Figures 7 - 9 shown in the figure, the lower nozzle assembly 1.5 includes 4 air nozzles 1.5.3, 4 pure water nozzles 1.5.4, 4 air connectors II 1.5.2, 4 water connectors II 1.5.5 and a connector mounting plate 1.5.1. The connector mounting plate 1.5.1 is installed on the dyeing housing 1.2. The air connectors II 1.5.2 and the water connectors II 1.5.5 are located on both sides of the connector mounting plate 1.5.1, and the air nozzles 1.5.3 and the pure water nozzles 1.5.4 are located above the connector mounting plate 1.5.1. With such a design, it is convenient for processing and installation, and it is also convenient to process 4 dyed glass slides simultaneously, with high efficiency.

[0048] As Figures 8 - 9 shown in the figure, a waterproof baffle 1.8 is provided between the Y-axis motion mechanism 1.7 and the dyeing spray head mechanism 1.4. With such a design, the Y-axis motion mechanism has a waterproof function and a good use effect.

[0049] As Figure 10 shown in the figure, the Y-axis motion mechanism 1.7 is a nut-screw motion mechanism, which includes a Y-axis motor 1.7.1, a driving gear 1.7.2, a driven gear 1.7.3, a screw 1.7.4, a guide rail 1.7.5, a nut-guide rail connection block 1.7.6, a slider 1.7.7, a linear bearing 1.7.8, a Y-axis bracket 1.7.9, and a guide shaft bracket 1.7.10. The Y-axis motor 1.7.1 is installed above the dyeing top cover 1.6. The driving gear 1.7.2 is installed on the motor shaft of the Y-axis motor 1.7.1. The driven gear 1.7.3 is installed on the screw 1.7.4, and the driven gear 1.7.3 meshes with the driving gear 1.7.2. The slider 1.7.7 is installed on the guide rail 1.7.5. The upper end of the nut-guide rail connection block 1.7.6 is installed on the screw 1.7.4 through a nut, and the lower end is installed on the guide rail 1.7.5 through the slider 1.7.7. The screw 1.7.4 is installed on the Y-axis bracket 1.7.9 through the guide shaft bracket 1.7.10. The Y-axis bracket 1.7.9 connects the screw 1.7.4 and the guide rail 1.7.5, and the nut-guide rail connection block 1.7.6 is connected to the bracket assembly 3.2. With such a design, it is convenient for processing and installation, operates stably, and has a good use effect.

[0050] As Figure 10As shown in the figure, it also includes a photoelectric induction sheet II 1.7.11, a photoelectric switch bracket 1.7.12, and a photoelectric switch II 1.7.13. The photoelectric induction sheet II 1.7.11 is installed on the nut guide rail connecting block 1.7.6, and the photoelectric switch bracket 1.7.12 and the photoelectric switch II 1.7.13 are installed on the dyeing housing 1.2 and are located below the driven gear 1.7.3. With such a design, the control accuracy is improved and the effect is good.

[0051] As Figure 11 shown in the figure, the drying module 2 includes a Z-axis lifting mechanism 2.1, a drying bracket assembly 2.2, and a heating assembly 2.3. The Z-axis lifting mechanism 2.1 is connected to the drying bracket assembly 2.2, and the heating assembly 2.3 is located in front of the drying bracket assembly 2.2. With such a design, it is convenient for processing and installation, has a reasonable layout, fewer moving mechanisms, and a good effect.

[0052] As Figures 12 - 13 shown in the figure, the Z-axis lifting mechanism 2.1 includes a stepping motor 2.1.1, a motor connecting frame 2.1.2, a gear II 2.1.3, a rack II 2.1.4, a guide rail fixing frame 2.1.5, a guide rail 2.1.6, and a slider 2.1.7. The stepping motor 2.1.1 is installed on the motor connecting frame 2.1.2, the gear II 2.1.3 is installed on the motor shaft of the stepping motor 2.1.1, the gear II 2.1.3 meshes with the rack II 2.1.4, the rack II 2.1.4 is installed on one side of the guide rail fixing frame 2.1.5, the guide rail 2.1.6 is installed on the other side of the guide rail fixing frame 2.1.5, the slider 2.1.7 is installed on the guide rail 2.1.6, and the slider 2.1.7 is connected to the motor connecting frame 2.1.2. With such a design, it is convenient for processing and installation and has a good effect.

[0053] As Figures 12 - 13 shown in the figure, it also includes a photoelectric induction sheet III 2.1.8 and a photoelectric switch III 2.1.9. The photoelectric induction sheet III 2.1.8 is installed on the motor connecting frame 2.1.2, and the photoelectric switch III 2.1.9 is installed below the guide rail fixing frame 2.1.5 and is located behind the rack 2.1.4. With such a design, the positioning accuracy is improved.

[0054] As Figures 12 - 13 shown in the figure, the drying bracket assembly 2.2 includes three vertically arranged drying brackets 2.2.2 horizontally placed, a drying bracket back plate 2.2.3, a drying bottom plate 2.2.1, and a bracket rib plate 2.2.4. The three drying brackets 2.2.2 are installed on the drying bracket back plate 2.2.3, the drying bracket back plate 2.2.3 is connected to the motor connecting frame 2.1.2, the guide rail fixing frame 2.1.5 is installed on the drying bottom plate 2.2.1, and the bracket rib plate 2.2.4 connects the guide rail fixing frame 2.1.5 and the drying bottom plate 2.2.1. With such a design, it is convenient for processing and installation, has good stability, and is convenient for the turnover of the glass slide transfer rack.

[0055] As Figures 12 - 13 shown, the heating assembly 2.3 includes a PTC heater 2.3.1, a fan 2.3.2 and a fan bracket 2.3.3. The PTC heater 2.3.1 is erected and perpendicular to the drying bracket 2.2.2. The fan 2.3.2 is located in front of the PTC heater 2.3.1 and parallel to the PTC heater 2.3.1. The fan 2.3.2 is installed on the fan bracket 2.3.3. Designed in this way, the drying method adopts side heating, and can dry the slides on the slide transfer rack at one time, effectively improving the drying efficiency.

[0056] In addition, a compression spring door is provided on the staining housing 1.2 near one side of the drying module 2. By setting the compression spring door, the drying module has a waterproof function, improving the convenience of use.

[0057] The working process of the above specific embodiment is as follows:

[0058] First, an empty slide transfer rack is placed on each of the upper drying bracket and the middle drying bracket in the initial state, without slides. After the upper drying bracket automatically places the slides and automatically adds samples through the manipulator (the position of the upper drying bracket is not shown in the figure, which is the position for dyeing and adding samples), the space height utilization is realized. After the sample is added, it is smeared to form a relatively thin sample layer, which is evenly laid on the specimen area above the slide. Under the action of the hot air generated by the PTC side drying module, the drying and fixation of the sample can be quickly completed, with high drying efficiency and reliable fixation effect. The Z-axis lifting mechanism of the drying module runs to the height where the upper drying bracket and the bracket assembly are converted. The bracket assembly completely extends out of the staining housing through the Y-axis moving mechanism and inserts into the gap between the upper drying bracket and the middle drying bracket. The Z-axis lifting mechanism descends a certain distance until the slide transfer rack completely detaches from the upper drying bracket. At this time, the S pole of the magnet of the bracket assembly and the N pole of the magnet of the slide transfer rack are attached, and the two are attracted by magnetic force. The bracket assembly drives the slide transfer rack to retract towards the direction close to the staining module through the Y-axis moving mechanism. The Z-axis lifting mechanism rises to the height where the lower drying bracket and the staining module are converted. The bracket assembly completely extends through the Y-axis moving mechanism until the slide transfer rack is directly above the lower drying bracket. The Z-axis lifting mechanism rises until the slide transfer rack is completely inserted into the lower drying bracket. At this time, the transfer of the slide transfer rack from the upper drying bracket to the lower drying bracket is completed. The bracket assembly retracts towards the direction close to the staining module through the Y-axis moving mechanism. The Z-axis lifting mechanism descends a certain distance. The bracket assembly completely extends through the Y-axis moving mechanism and inserts into the gap between the middle drying bracket and the slide transfer rack. The Z-axis lifting mechanism descends a certain distance until the slide transfer rack completely detaches from the middle drying bracket. At this time, the S pole of the magnet of the bracket assembly and the N pole of the magnet of the slide transfer rack are attached, and the two are attracted by magnetic force.

[0059] Then, the bracket assembly retracts towards the dyeing module through the Y-axis motion mechanism. The Z-axis lifting mechanism descends to the height where the upper drying bracket and the dyeing module are switched. The bracket assembly fully extends through the Y-axis motion mechanism until the slide transfer rack is directly above the upper drying bracket. The Z-axis lifting mechanism ascends until the slide transfer rack is fully inserted into the upper drying bracket. At this time, the transfer of the slide transfer rack from the middle drying bracket to the upper drying bracket is completed. The bracket assembly retracts towards the dyeing module through the Y-axis motion mechanism. The Z-axis lifting mechanism ascends to the switching height between the bracket assembly and the lower drying bracket. After the sample is dried, the bracket assembly fully extends through the Y-axis motion mechanism and inserts into the gap between the lower drying bracket and the slide transfer rack. The Z-axis lifting mechanism descends a certain distance until the slide transfer rack is completely separated from the upper drying bracket. The bracket assembly retracts towards the dyeing module through the Y-axis motion mechanism and enters the dyeing module, and then performs dyeing through the X-axis motion mechanism and the dyeing nozzle mechanism. After the last process of dyeing the sample, that is, after the air blowing of the upper and lower air nozzles, only a few tiny droplets or a thin liquid film remain on the upper and lower sides of the slide. Under the action of the hot air generated by the PTC side drying module, the drying of the dyed sample can be quickly completed, with high drying efficiency, no impact on dyeing, and high overall turnover efficiency of drying.

[0060] Finally, after the dyeing is completed, the Z-axis lifting mechanism moves to the height where the bracket assembly and the middle drying bracket are switched. The bracket assembly fully extends through the Y-axis motion mechanism and inserts into the gap between the middle drying bracket and the slide transfer rack. The Z-axis lifting mechanism descends a certain distance until the slide transfer rack is completely separated from the middle drying bracket. At this time, the dyed slides on the just-dyed slide transfer rack are dried, and the dried slides are taken out by other mechanisms. Since there is a set of slide transfer racks for both the upper drying bracket and the middle drying bracket, the entire process can be cycled. This solution does not limit the number of drying brackets, the slides set on the drying brackets, and the PTC heaters. As long as the operating logic is reasonable, the number can be set according to the equipment efficiency requirements.

[0061] The above specific implementation manners are only specific cases of the present invention and do not limit the present invention in other forms. Any person skilled in the art may use the disclosed technical content to make changes or modifications into equivalent implementation manners with equivalent changes. However, any simple modification, equivalent change, and modification made to the above implementation manners based on the technical essence of the present invention without departing from the technical principle of the present invention shall fall within the patent protection scope of the present invention.

Claims

1. An integrated device for slide staining and drying, comprising a staining module (1) and a drying module (2), characterized in that: A slide transfer assembly (3) for turnover is provided between the staining module (1) and the drying module (2); The staining module (1) includes an X-axis movement mechanism (1.3), a Y-axis movement mechanism (1.7), a staining housing (1.2), a staining top cover (1.6), a staining nozzle mechanism (1.4) and a lower nozzle assembly (1.5). The X-axis movement mechanism (1.3) is installed above the staining top cover (1.6). The X-axis movement mechanism (1.3) is connected to the staining nozzle mechanism (1.4). The staining nozzle mechanism (1.4) is located inside the staining housing (1.2) and above the lower nozzle assembly (1.5). Both the lower nozzle assembly (1.5) and the Y-axis movement mechanism (1.7) are installed on the staining housing (1.2); The X-axis movement mechanism (1.3) is a gear-rack movement mechanism, which includes an X-axis motor (1.3.1), a motor mounting plate (1.3.2), a gear I (1.3.3), a rack I (1.3.4), and a guide rail slider (1.3.5). The motor mounting plate (1.3.2) is installed above the staining housing (1.2). The X-axis motor (1.3.1) is installed on the motor mounting plate (1.3.2). The gear I (1.3.3) is connected to the motor shaft and meshes with the rack I (1.3.4). The guide rail slider (1.3.5) is arranged parallel to the rack I (1.3.4); The staining nozzle mechanism (1.4) includes a nozzle support (1.4.1), a dye solution nozzle with a connector (1.4.2), a water connector I (1.4.3), an air connector I (1.4.4), a water nozzle (1.4.5), and an air nozzle (1.4.6). The nozzle support (1.4.1) is connected to the motor mounting plate (1.3.2) through a nozzle connecting frame. The dye solution nozzle with a connector (1.4.2), the water connector I (1.4.3), the air connector I (1.4.4), the water nozzle (1.4.5), and the air nozzle (1.4.6) are all installed on the nozzle support (1.4.1); The slide transfer assembly (3) includes a bracket assembly (3.2), a slide transfer rack (3.1), and a clamping mechanism (3.3). The bracket assembly (3.2) is connected to the Y-axis movement mechanism (1.7). The bracket assembly (3.2) detachably places the slide transfer rack (3.1). The clamping mechanism (3.3) is installed on the slide transfer rack (3.1); One set of the drying module (2) is provided; The drying module (2) includes a Z-axis lifting mechanism (2.1), a drying bracket assembly (2.2), and a heating component (2.3). The Z-axis lifting mechanism (2.1) is connected to the drying bracket assembly (2.2). The heating component (2.3) is located in front of the drying bracket assembly (2.2); The Z-axis lifting mechanism (2.1) includes a stepper motor (2.1.1), a motor connecting frame (2.1.2), a gear II (2.1.3), a rack II (2.1.4), a guide rail fixing frame (2.1.5), a guide rail (2.1.6), and a slider (2.1.7). The stepper motor (2.1.1) is installed on the motor connecting frame (2.1.2), and the gear II (2.1.3) is installed on the motor shaft of the stepper motor ( 2.1.1). The gear II (2.1.3) meshes with the rack II (2.1.4). The rack II (2.1.4) is installed on one side of the guide rail fixing frame (2.1.5). The guide rail (2.1.6) is installed on the other side of the guide rail fixing frame (2.1.5). The slider (2.1.7) is installed on the guide rail (2.1.6), and the slider (2.1.7) is connected to the motor connecting frame (2.1.2). The drying bracket assembly (2.2) includes three drying brackets (2.2.2) arranged vertically and horizontally, a drying bracket back plate (2.2.3), a drying bottom plate (2.2.1), and a bracket rib plate (2.2.4). The three drying brackets (2.2.2) are installed on the drying bracket back plate (2.2.3). The drying bracket back plate (2.2.3) is connected to the motor connecting frame (2.1.2). The guide rail fixing frame (2.1.5) is installed on the drying bottom plate (2.2.1). The bracket rib plate (2.2.4) connects the guide rail fixing frame (2.1.5) and the drying bottom plate (2.2.1).

2. The integrated device for slide staining and drying according to claim 1, wherein: The bracket assembly (3.2) includes a bracket body (3.2.1), a bracket connecting piece (3.2.2), and a first magnet (3.2.3). The bracket body (3.2.1) is connected to the Y-axis moving mechanism (1.7) through the bracket connecting piece (3.2.2). The first magnet (3.2.3) is installed on the bracket body (3.2.1).

3. A slide staining and drying integrated device according to any one of claims 1 or 2, characterized in that: The slide glass transfer rack (3.1) is used to carry a plurality of slide glasses (4). Each slide glass (4) is automatically inserted into the corresponding clamping mechanism (3.3) on the slide glass transfer rack (3.1) by a manipulator. Each clamping mechanism (3.3) includes a clamping support (3.3.1), a spring piece (3.3.2), and a locking screw (3.3.3). The clamping support (3.3.1) and the slide glass transfer rack (3.1) are integrally formed. The spring piece (3.3.2) is installed on the clamping support (3.3.1) through the locking screw (3.3.3). A second magnet (3.1.1) is installed on the clamping support (3.3.1).

4. The integrated device for slide staining and drying according to claim 1, wherein: The Y-axis motion mechanism (1.7) is a nut-screw motion mechanism, which includes a Y-axis motor (1.7.1), a driving gear (1.7.2), a driven gear (1.7.3), a screw rod (1.7.4), a guide rail (1.7.5), a nut-guide rail connecting block (1.7.6), a slider (1.7.7), a linear bearing (1.7.8), a Y-axis bracket (1.7.9), and a guide shaft bracket (1.7.10). The Y-axis motor (1.7.1) is installed above the dyeing top cover (1.6). The driving gear (1.7.2) is installed on the motor shaft of the Y-axis motor (1.7.1). The driven gear (1.7.3) is installed on the screw rod (1.7.4). The driven gear (1.7.3) meshes with the driving gear (1.7.2). The slider (1.7.7) is installed on the guide rail (1.7.5). The upper end of the nut-guide rail connecting block (1.7.6) is installed on the screw rod (1.7.4) through a nut, and the lower end is installed on the guide rail (1.7.5) through the slider (1.7.7). The screw rod (1.7.4) is installed on the Y-axis bracket (1.7.9) through the guide shaft bracket (1.7.10). The Y-axis bracket (1.7.9) connects the screw rod (1.7.4) and the guide rail (1.7.5). The nut-guide rail connecting block (1.7.6) is connected to the bracket assembly (3.2).

5. The integrated device for slide staining and drying according to claim 1, characterized in that: The heating assembly (2.3) includes a PTC heater (2.3.1), a fan (2.3.2), and a fan bracket (2.3.3). The PTC heater (2.3.1) is erected and perpendicular to the drying bracket (2.2.2). The fan (2.3.2) is located in front of the PTC heater (2.3.1) and parallel to the PTC heater (2.3.1). The fan (2.3.2) is installed on the fan bracket (2.3.3).

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