Pressure jacket and syringe retention features for angiography fluid injector

Abstract

An assembly for holding a pressure jacket (134) and a syringe (132) on a fluid injector, the assembly comprising: a base plate (1902) including a body (1904); at least a first holding arm (1910a) and a second holding arm (1910b) operably mounted on the body of the base plate, the first holding arm having a first holding surface at a distal end thereof and the second holding arm having a second holding surface at a distal end thereof, wherein the first holding surface and the second holding surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operably connected to at least one of the first holding arm and the second holding arm, wherein the linkage assembly is configured to move at least one of the first holding arm and the second holding arm between at least a first open position and a closed position.

Description

[0001] Cross Reference to Related Applications

[0002] This application claims priority to U.S. Provisional Patent Application No. 62 / 898,289, filed September 10, 2019, and U.S. Provisional Patent Application No. 62 / 979,048, filed February 20, 2020, the disclosures of which are incorporated by reference herein in their entireties. TECHNICAL FIELD

[0003] The present disclosure relates generally to an angiographic fluid injector having one or more syringe retention features configured to retain a syringe and a pressure jacket, wherein the syringe retention features engage a distal end of the syringe and the pressure jacket to limit movement of the syringe in a distal direction during a fluid injection procedure and to support the distal end of the syringe under pressure. BACKGROUND

[0004] In many medical diagnostic and therapeutic procedures, medical practitioners inject one or more medical fluids into a patient. In recent years, a variety of injector-actuated syringes and powered fluid injectors have been developed for the pressurized injection of medical fluids, such as contrast media (often referred to simply as “contrast”), flushing agents such as saline, and other medical fluids, for use in contrast-enhanced imaging procedures such as cardiovascular angiography (CV), computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), positron emission tomography (PET), and other imaging procedures. Typically, these fluid injectors are designed to deliver a preset amount of one or more fluids at a preset pressure and / or flow rate.

[0005] Typically, the fluid injector has at least one drive member, such as a piston, that is connected to the syringe, for example by connection with an engagement feature on the plunger or a proximal end wall of the syringe. The syringe can include a rigid barrel, with a syringe plunger slidably disposed within the barrel. In some examples, the syringe can include a rolling diaphragm barrel configuration having a flexible sidewall configured to roll on itself, with a proximal end wall of the syringe body releasably engageable with the at least one drive member. The drive member drives the plunger or rolling diaphragm / proximal end wall in a proximal direction and / or a distal direction relative to a longitudinal axis of the barrel to draw fluid into or deliver fluid from the syringe barrel.

[0006] Syringes used with fluid injectors can be made from various medical grade plastic materials having a certain minimum wall thickness. Syringe thickness is an important design factor because fluid pressures up to 1200 psi can be used during an injection procedure. During certain injection procedures, the injector itself can not be able to withstand the high pressure without excessive radial expansion of the syringe wall under such pressures. This can result in undesirable changes in fluid delivery volume and flow rate, and can even result in structural failure. Fluid injectors having at least one pressure jacket have been developed for enclosing at least a portion of the syringe and preventing radial expansion of the syringe due to the buildup of fluid pressure within the syringe. Conventional pressure jacket designs include a rigid cylindrical pressure jacket that engages a rigid cap at a distal end to hold the syringe within the pressure jacket.

[0007] There is a current need in the art for a syringe retention interface that assists in limiting movement and / or expansion of an injector within a pressure jacket during a fill procedure or pressurized injection fluid delivery procedure. In one example, there is a need for a syringe retention interface that assists in limiting movement of a syringe in a distal direction relative to a pressure jacket and / or an injector housing during an injection procedure while still allowing for ready insertion and removal of the syringe and / or pressure jacket. SUMMARY

[0008] In view of the foregoing need, systems and methods for retaining at least one syringe in a medical injector during injection of a medical fluid are provided. In some examples of the present disclosure, an assembly for retaining a pressure jacket and a syringe on a fluid injector is described. The assembly includes a base plate including a body, at least a first retention arm and a second retention arm operably mounted on the body of the base plate, the first retention arm having a first retention surface at a distal end thereof and the second retention arm having a second retention surface at a distal end thereof. The first retention surface and the second retention surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe. The assembly further includes a linkage assembly operably connected to at least one of the first retention arm and the second retention arm. The linkage assembly is configured to move at least one of the first retention arm and the second retention arm between at least a first open position and a closed position.

[0009] In further examples of the present disclosure, a linkage assembly is operably connected to a proximal end of the first retaining arm and a proximal end of the second retaining arm. The linkage assembly operably connects the first retaining arm to the second retaining arm such that the first retaining arm and the second retaining arm are configured to move in unison between at least the first open position and the closed position. The linkage assembly includes at least one biasing member configured to bias the first retaining arm and the second retaining arm to move in unison between at least the first open position and the closed position. The first retaining arm and the second retaining arm are connected to the body of the base plate at a first pivot point and a second pivot point, respectively, such that the first retaining arm and the second retaining arm pivot about the first pivot point and the second pivot point between at least the first open position and the closed position. The first retaining arm and the second retaining arm are further configured to move to a second open position between the first open position and the closed position. In the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector and / or removal of at least one of the pressure jacket and the syringe from the fluid injector. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance to retain the pressure jacket and the syringe between the first retaining arm and the second retaining arm. In the second open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a third distance to retain the pressure jacket in the fluid injector and allow insertion and removal of the syringe from the fluid injector. The first distance is greater than the second distance. The third distance is less than the first distance and greater than the second distance. Each of the first retaining arm and the second retaining arm includes at least one base member operably connected to the body of the base plate and at least one retaining portion disposed on a distal end of the at least one base member. The first retaining surface of the first retaining arm includes a first syringe retaining surface and a first pressure jacket retaining surface. The second retaining surface of the second retaining arm includes a second syringe retaining surface and a second pressure jacket retaining surface. The at least one biasing member is configured to bias the first retaining arm and the second retaining arm in at least one of the first open position, the closed position, or the second open position such that the arms will be retained in the first open position, the closed position, or the second open position. In particular embodiments, the at least one biasing member is configured to bias the first retaining arm and the second retaining arm in the first open position and the closed position such that the arms will be retained in the first open position and the closed position.

[0010] In other examples of the present disclosure, an assembly for retaining a pressure jacket and a syringe in a fluid injector is described. The assembly includes a base plate including a body, and at least a first retaining arm and a second retaining arm operably mounted on the body of the base plate. The first retaining arm has a first retaining surface at a distal end thereof, and the second retaining arm has a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe. Each of the first retaining arm and the second retaining arm includes at least one base member operably connected to the body of the base plate, and at least one retaining portion disposed on a distal end of the at least one base member, the at least one retaining portion configured to engage the at least one of the pressure jacket and the syringe.

[0011] In other examples of the present disclosure, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each include at least one inner protrusion to engage a distal end of at least one of the pressure jacket and the syringe. At least one of the inner protrusions is a syringe retaining protrusion that extends at an angle relative to a longitudinal axis of the syringe and is configured to interact with a corresponding angled distal surface of a circumferential wall on a distal end of the syringe to urge the distal ends of the first retaining arm and the second retaining arm with an inward retaining force. In certain aspects, at least one of the first retaining arm and the second retaining arm includes at least one finger configured to assist in moving the first retaining arm and the second retaining arm between a closed position and an open position. In other aspects, each of the first retaining arm and the second retaining arm includes at least one finger to assist in moving the first retaining arm and the second retaining arm between a closed position and an open position. In certain aspects, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each define a retaining groove to receive at least a portion of a distal end of the pressure jacket. In the open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector, and / or removal of at least one of the pressure jacket and the syringe from the fluid injector. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance configured to retain the pressure jacket and the syringe between the first retaining arm and the second retaining arm. The first distance is greater than the second distance. The retaining portions of the first retaining arm and the second retaining arm have a curvature relative to the longitudinal axis of the syringe that corresponds to at least a portion of a distal end of at least one of the pressure jacket and the syringe.

[0012] In further examples of the present disclosure, an assembly for retaining a pressure jacket and a syringe on a fluid injector is described. The assembly includes a base plate including a main body, at least a first retaining arm and a second retaining arm operably mounted on the main body of the base plate. The first retaining arm has a first retaining surface at a distal end thereof, and the second retaining arm has a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe. The assembly further includes a linkage assembly operably connected to the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position. Each of the first retaining arm and the second retaining arm includes at least one base member operably connected to the main body of the base plate and at least one retaining portion disposed on a distal end of the at least one base member, the at least one retaining portion configured to engage at least one of the pressure jacket and the syringe when in the closed position. The first retaining surface of the first retaining arm is disposed on the retaining portion of the first retaining arm, and the second retaining surface of the second retaining arm is disposed on the retaining portion of the second retaining arm.

[0013] In further examples of the present disclosure, a linkage assembly is operably connected to a proximal end of the first retention arm and a proximal end of the second retention arm. The linkage assembly operably connects the first retention arm to the second retention arm such that the first retention arm and the second retention arm are configured to move in unison between at least a first open position and a closed position. The linkage assembly includes at least one biasing member configured to bias the first retention arm and the second retention arm to move in unison between at least the first open position and the closed position. The first retention arm and the second retention arm are connected to the body of the base plate at a first pivot point and a second pivot point, respectively, such that the first retention arm and the second retention arm pivot about the first pivot point and the second pivot point between at least the first open position and the closed position. The first retention arm and the second retention arm are further configured to move to a second open position between the first open position and the closed position. In the first open position, the first retention surface of the first retention arm and the second retention surface of the second retention arm are separated from each other by a first distance, the first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector and / or removal of at least one of the pressure jacket and the syringe from the fluid injector. In the closed position, the first retention surface of the first retention arm and the second retention surface of the second retention arm are separated from each other by a second distance, the second distance configured to retain the pressure jacket and the syringe between the first retention arm and the second retention arm. The first distance is greater than the second distance. The first retention surface of the first retention arm and the second retention surface of the second retention arm each include at least one inner protrusion to engage a distal end of at least one of the pressure jacket and the syringe. In certain aspects, the at least one inner protrusion is a syringe retention protrusion that extends at an angle relative to a longitudinal axis of the syringe and is configured to interact with a corresponding angled distal surface of a circumferential wall on the distal end of the syringe to urge the distal end of the first retention arm and the second retention arm with an inward retention force. In certain aspects, at least one of the first retention arm and the second retention arm includes at least one finger configured to assist in moving the first retention arm and the second retention arm between the closed position and the open position. In certain aspects, each of the first retention arm and the second retention arm includes at least one finger configured to assist in moving the first retention arm and the second retention arm between the closed position and the open position. In certain aspects, the first retention surface of the first retention arm and the second retention surface of the second retention arm each define a retention groove to receive at least a portion of the distal end of the pressure jacket. The first retention surface of the first retention arm and the second retention surface of the second retention arm have a curvature relative to the longitudinal axis of the syringe that corresponds to at least a portion of the distal end of at least one of the pressure jacket and the syringe.

[0014] In further examples of the present disclosure, a fluid injector including an assembly for holding pressure jackets and syringes is described. The fluid injector includes an injector housing, at least one port defined in the injector housing to receive at least one syringe, wherein the syringe is received within at least one pressure jacket, and an assembly for holding the at least one pressure jacket on the fluid injector and the at least one syringe in the at least one port. The assembly includes a base plate including a main body, at least a first holding arm and a second holding arm operably mounted on the main body of the base plate, and including features in accordance with various aspects of the syringe and pressure jacket holding assemblies described herein.

[0015] In certain aspects, an electromechanical motor is disposed in the injector housing to move the first holding arm and the second holding arm between the first open position and the closed position, while in other aspects, movement of the first holding arm and the second holding arm between the first open position and the closed position can be performed manually.

[0016] In particular embodiments, the holding features can be used in cardiovascular angiography (CV) injectors, which typically require injection pressures of up to 1200 psi. As described herein, such holding features and holding elements can provide particular designs and features to withstand the increased injection pressures.

[0017] The following clauses also recite further features of the present disclosure:

[0018] Clause 1 : An assembly for holding a pressure jacket and a syringe on a fluid injector, the assembly comprising: a base plate including a main body; at least a first holding arm and a second holding arm operably mounted on the main body of the base plate, the first holding arm having a first holding surface at a distal end thereof and the second holding arm having a second holding surface at a distal end thereof, wherein the first holding surface and the second holding surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operably connected to at least one of the first holding arm and the second holding arm, wherein the linkage assembly is configured to move at least one of the first holding arm and the second holding arm between at least a first open position and a closed position.

[0019] Clause 2: The assembly according to Clause 1, wherein the linkage assembly is operably connected to a proximal end of the first holding arm and a proximal end of the second holding arm.

[0020] Clause 3: The assembly according to Clause 1 or 2, wherein the linkage assembly operably connects the first holding arm to the second holding arm such that the first holding arm and the second holding arm are configured to move in unison between at least the first open position and the closed position.

[0021] Clause 4: The assembly of clause 3, wherein the linkage assembly includes at least one biasing member configured to bias the first retaining arm and the second retaining arm to move in unison between at least the first open position and the closed position.

[0022] Clause 5: The assembly of any one of clauses 1-4, wherein the first retaining arm and the second retaining arm are connected to the body of the base plate at first and second pivot points, respectively, such that the first retaining arm and the second retaining arm pivot about the first and second pivot points between at least the first open position and the closed position.

[0023] Clause 6: The assembly of any one of clauses 1-5, wherein the first retaining arm and the second retaining arm are further configured to move to a second open position between the first open position and the closed position.

[0024] Clause 7: The assembly of clause 6, wherein, in the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector or removal of at least one of the pressure jacket and the syringe from the fluid injector, wherein, in the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance to retain the pressure jacket and the syringe between the first retaining arm and the second retaining arm, wherein, in the second open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a third distance to retain the pressure jacket in the fluid injector and allow removal of the syringe from the fluid injector, wherein the first distance is greater than the second distance, and wherein the third distance is less than the first distance and greater than the second distance.

[0025] Clause 8: The assembly of any one of clauses 1-7, wherein, in the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector or removal of at least one of the pressure jacket and the syringe from the fluid injector, wherein, in the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance to retain the pressure jacket and the syringe between the first retaining arm and the second retaining arm, and wherein the first distance is greater than the second distance.

[0026] Clause 9: The assembly of any one of clauses 1-8, wherein each of the first retaining arm and the second retaining arm includes at least one base member operably connected to the body of the base plate, and at least one retaining portion disposed on a distal end of the at least one base member.

[0027] Clause 10: The assembly of any of clauses 1-9, wherein the first retention surface of the first retention arm comprises a first syringe retention surface and a first pressure jacket retention surface, and wherein the second retention surface of the second retention arm comprises a second syringe retention surface and a second pressure jacket retention surface.

[0028] Clause 11 : The assembly of any of clauses 4-10, wherein the at least one biasing member is configured to bias the first retention arm and the second retention arm in the first open position or the second open position.

[0029] Clause 12: An assembly for retaining a pressure jacket and a syringe in a fluid injector, the assembly comprising: a base plate comprising a body; and at least a first retention arm and a second retention arm operably mounted on the body of the base plate, the first retention arm having a first retention surface at a distal end thereof and the second retention arm having a second retention surface at a distal end thereof, wherein the first retention surface and the second retention surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe, wherein each of the first retention arm and the second retention arm comprises at least one base member operably connected to the body of the base plate, and at least one retention portion disposed on a distal end of the at least one base member, the at least one retention portion configured to engage the at least one of the pressure jacket and the syringe.

[0030] Clause 13: The assembly of clause 12, wherein the first retention surface of the first retention arm and the second retention surface of the second retention arm each comprise at least one inner protrusion to engage a distal end of the at least one of the pressure jacket and the syringe.

[0031] Clause 14: The assembly of clause 13, wherein the at least one inner protrusion is a syringe retention protrusion that extends at an angle relative to a longitudinal axis of the syringe, the syringe configured to interact with a corresponding angled surface of a circumferential wall on a distal end of the syringe to urge the distal ends of the first retention arm and the second retention arm with an inward retention force.

[0032] Clause 15: The assembly of any of clauses 12-14, wherein at least one of the first retention arm and the second retention arm comprises at least one finger configured to assist in moving the first retention arm and the second retention arm between the closed position and the open position.

[0033] Clause 16: The assembly of any of clauses 12-15, wherein each of the first retention arm and the second retention arm comprises at least one finger to assist in moving the first retention arm and the second retention arm between the closed position and the open position.

[0034] Clause 17: The assembly of any of clauses 12-16, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each define a retaining groove to receive at least a portion of a distal end of the pressure jacket.

[0035] Clause 18: The assembly of any of clauses 12-17, wherein, in the open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector or removal of at least one of the pressure jacket and the syringe from the fluid injector, wherein, in the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance, the second distance configured to retain the pressure jacket and the syringe between the first retaining arm and the second retaining arm, and wherein the first distance is greater than the second distance.

[0036] Clause 19: The assembly of any of clauses 12-18, wherein the retaining portion of the first retaining arm and the second retaining arm have a curvature relative to a longitudinal axis of the syringe, the curvature corresponding to a distal end of at least one of the pressure jacket and the syringe.

[0037] Clause 20: An assembly for retaining a pressure jacket and a syringe on a fluid injector, the assembly comprising: a base plate comprising a body; at least a first retaining arm and a second retaining arm, the at least first retaining arm and second retaining arm operably mounted on the body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operably connected to the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position, and wherein each of the first retaining arm and the second retaining arm comprises at least one base member operably connected to the body of the base plate and at least one retaining portion disposed on a distal end of the at least one base member, the at least one retaining portion configured to engage at least one of the pressure jacket and the syringe when in the closed position, wherein the first retaining surface of the first retaining arm is disposed on the retaining portion of the first retaining arm and the second retaining surface of the second retaining arm is disposed on the retaining portion of the second retaining arm.

[0038] Clause 21 : The assembly of clause 20, wherein the linkage assembly is operably connected to a proximal end of the first retaining arm and a proximal end of the second retaining arm.

[0039] Clause 22: The assembly of clauses 20 or 21, wherein the linkage assembly operably connects the first retention arm to the second retention arm such that the first retention arm and the second retention arm are configured to move in unison between at least the first open position and the closed position.

[0040] Clause 23: The assembly of clause 22, wherein the linkage assembly includes at least one biasing member configured to bias the first retention arm and the second retention arm to move in unison between at least the first open position and the closed position.

[0041] Clause 24: The assembly of any of clauses 20 to 23, wherein the first retention arm and the second retention arm are connected to the body of the base plate at first and second pivot points, respectively, such that the first retention arm and the second retention arm pivot about the first and second pivot points between at least the first open position and the closed position.

[0042] Clause 25: The assembly of any of clauses 20 to 24, wherein the first retention arm and the second retention arm are further configured to move to a second open position between the first open position and the closed position.

[0043] Clause 26: The assembly of any of clauses 20 to 25, wherein, in the first open position, the first retention surface of the first retention arm and the second retention surface of the second retention arm are separated from each other by a first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector or removal of at least one of the pressure jacket and the syringe from the fluid injector, wherein, in the closed position, the first retention surface of the first retention arm and the second retention surface of the second retention arm are separated from each other by a second distance configured to retain the pressure jacket and the syringe between the first retention arm and the second retention arm, and wherein the first distance is greater than the second distance.

[0044] Clause 27: The assembly of any of clauses 20 to 26, wherein the first retention surface of the first retention arm and the second retention surface of the second retention arm each include at least one inner protrusion to engage a distal end of at least one of the pressure jacket and the syringe.

[0045] Clause 28: The assembly of clause 27, wherein the at least one inner protrusion is a syringe retention protrusion that extends at an angle relative to a longitudinal axis of the syringe and is configured to interact with a corresponding angled surface of a circumferential wall on the distal end of the syringe to urge the distal end of the first retention arm and the second retention arm with an inward retention force.

[0046] Clause 29: The assembly of any of clauses 20-28, wherein at least one of the first retaining arm and the second retaining arm includes at least one finger configured to assist in moving the first retaining arm and the second retaining arm between the closed position and the open position.

[0047] Clause 30: The assembly of any of clauses 20-29, wherein each of the first retaining arm and the second retaining arm includes at least one finger configured to assist in moving the first retaining arm and the second retaining arm between the closed position and the open position.

[0048] Clause 31 : The assembly of any of clauses 20-30, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each define a retaining recess to receive at least a portion of a distal end of the pressure jacket.

[0049] Clause 32: The assembly of any of clauses 20-31, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm have a curvature relative to a longitudinal axis of the syringe, the curvature corresponding to a distal end of at least one of the pressure jacket and the syringe.

[0050] Clause 33: A fluid injector, the fluid injector comprising: an injector housing; at least one port defined in the injector housing to receive at least one syringe, wherein the syringe is received within at least one pressure jacket; and an assembly for retaining the at least one pressure jacket on the fluid injector and the at least one syringe in the at least one port, the assembly comprising: a base plate comprising a main body; at least a first retaining arm and a second retaining arm, the at least first retaining arm and second retaining arm operably mounted on the main body of the base plate, the first retaining arm having a first retaining surface at a distal end thereof and the second retaining arm having a second retaining surface at a distal end thereof, wherein the first retaining surface and the second retaining surface are configured to abut a distal surface of at least one of the pressure jacket and the syringe; a linkage assembly operably connected to at least one of the first retaining arm and the second retaining arm, wherein the linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position, and wherein each of the first retaining arm and the second retaining arm includes at least one base member operably connected to the main body of the base plate and at least one retaining portion disposed on a distal end of the at least one base member to engage at least one of the pressure jacket and the syringe when in the closed position.

[0051] Clause 34: The fluid injector of clause 33, wherein the linkage assembly is operably connected to a proximal end of the first retaining arm and a proximal end of the second retaining arm.

[0052] Clause 35: The fluid injector of clauses 33 or 34, wherein the linkage assembly operably connects the first retention arm to the second retention arm such that the first retention arm and the second retention arm are configured to move in unison between at least the first open position and the closed position.

[0053] Clause 36: The fluid injector of clause 35, wherein the linkage assembly includes at least one biasing member configured to bias the first retention arm and the second retention arm to move in unison between at least the first open position and the closed position.

[0054] Clause 37: The fluid injector of any of clauses 33 to 36, wherein the first retention arm and the second retention arm are connected to the body of the base plate at first and second pivot points, respectively, such that the first retention arm and the second retention arm pivot about the first and second pivot points between at least the first open position and the closed position.

[0055] Clause 38: The fluid injector of any of clauses 33 to 37, wherein the first retention arm and the second retention arm are further configured to move to a second open position between the first open position and the closed position.

[0056] Clause 39: The fluid injector of any of clauses 33 to 38, wherein, in the first open position, the first retention surface of the first retention arm and the second retention surface of the second retention arm are separated from each other by a first distance configured to allow insertion and engagement of at least one of the pressure jacket and the syringe with the fluid injector or removal of at least one of the pressure jacket and the syringe from the fluid injector, wherein, in the closed position, the first retention surface of the first retention arm and the second retention surface of the second retention arm are separated from each other by a second distance configured to retain the pressure jacket and the syringe between the first retention arm and the second retention arm, and wherein the first distance is greater than the second distance.

[0057] Clause 40: The fluid injector of any of clauses 33 to 39, wherein the first retention surface of the first retention arm and the second retention surface of the second retention arm each include at least one inner protrusion to engage a distal end of at least one of the pressure jacket and the syringe.

[0058] Clause 41: The fluid injector of clause 40, wherein the at least one inner protrusion is a syringe retention protrusion that extends at an angle relative to a longitudinal axis of the syringe, the syringe configured to interact with a corresponding angled surface of a circumferential wall on a distal end of the syringe to urge the distal end of the first retention arm and the second retention arm with an inward retention force.

[0059] Clause 42: The fluid injector of any of clauses 33-41, wherein at least one of the first retention arm and the second retention arm includes at least one finger configured to assist in moving the first retention arm and the second retention arm between the closed position and the first open position.

[0060] Clause 43: The fluid injector of any of clauses 33-42, wherein each of the first retention arm and the second retention arm includes at least one finger configured to assist in moving the first retention arm and the second retention arm between the closed position and the first open position.

[0061] Clause 44: The fluid injector of any of clauses 33-43, wherein the first retention surface of the first retention arm and the second retention surface of the second retention arm each define a retention groove to receive at least a portion of a distal end of the pressure jacket.

[0062] Clause 45: The fluid injector of any of clauses 33-44, wherein the first retention surface of the first retention arm and the second retention surface of the second retention arm have a curvature relative to a longitudinal axis of the syringe, the curvature corresponding to a distal end of at least one of the pressure jacket and the syringe.

[0063] Clause 46: The fluid injector of any of clauses 33-45, further comprising an electromechanical motor disposed in the injector housing to move the first retention arm and the second retention arm between the open position and the closed position.

[0064] Clause 47: The fluid injector of any of clauses 33-46, wherein the syringe includes a drip flange disposed on a distal end of the syringe, and wherein the first retention surface of the first retention arm and the second retention surface of the second retention arm are configured to engage the drip flange of the syringe to retain the syringe in the at least one port of the injector housing.

[0065] Further details and advantages of the various examples described in detail herein will become clear upon review of the following detailed description of the various examples in view of the drawings. BRIEF DESCRIPTION OF DRAWINGS

[0066] Figure 1 FIG. 1 shows a perspective view of a fluid injector configured for use in a multi-fluid delivery system according to one example or aspect of the present disclosure;

[0067] Figure 2A and 2B FIG. 1 shows a perspective view of a fluid injector configured for use in a multi-fluid delivery system according to one example or aspect of the present disclosure;

[0068] Figure 3A and 3B FIG. 1 shows a perspective view of a fluid injector configured for use in a multi-fluid delivery system according to one example or aspect of the present disclosure;

[0069] Figure 4A 、 Figure 4B and Figure 4C shows another pivoting clamp hold element for CV applications according to various embodiments.

[0070] Figure 5A and 5B shows a hold element for CV applications with rotatable pressure jacket according to various embodiments.

[0071] Figures 6A-6E shows a hold element for CV applications with breech loading according to various embodiments.

[0072] Figures 7A-7D shows a front loading sliding hold element for CV applications according to various embodiments.

[0073] Figures 8A-8E shows a fixed hold element and two piece pressure jacket for CV applications according to various embodiments.

[0074] Figure 9A and 9B shows a rotating hold element for CV applications with hinged pressure jacket hold features according to various embodiments.

[0075] Figure 10A and 10B shows a hold element for CV applications with pressure jacket on rotatable plate according to various embodiments.

[0076] Figures 11A-11I shows a fluid injector front plate with 3 position breech loading pressure jacket carrier configuration according to one embodiment.

[0077] Figures 12A-12H shows a fluid injector with 2 position breech loading pressure jacket carrier configuration according to one embodiment.

[0078] Figures 13A-13E shows a mechanism for engaging a pressure jacket in a receiving portion of a fluid injector carrier according to one embodiment.

[0079] Figures 14A-14F shows an alternative mechanism for engaging a pressure jacket in a receiving portion of a fluid injector carrier according to one embodiment.

[0080] Figures 15A-15C shows an embodiment of a front loading pressure jacket hold mechanism with syringe and pressure jacket in a closed position according to aspects of the present disclosure. Figure 15A is an isometric view of a hold mechanism.Figure 15B is a side view of a linkage arrangement of the retention mechanism. Figure 15C is a cross-sectional view of a support arm for the distal retention surface.

[0081] Figures 16A-16C shows the front-loading pressure jacket retention mechanism in a second open position. Figures 15A-15C Figure 16A is a perspective view of the retention mechanism. Figure 16B is a side view of a linkage arrangement of the retention mechanism. Figure 16C is a cross-sectional view of a support arm for the distal retention surface.

[0082] Figures 17A-17C shows the front-loading pressure jacket retention mechanism in a first open position. Figures 15A-15C Figure 17A is a perspective view of the retention mechanism. Figure 17B is a side view of a linkage arrangement of the retention mechanism. Figure 17C is a cross-sectional view of a support arm for the distal retention surface.

[0083] Figure 18 is a perspective view of a front-loading pressure jacket retention mechanism according to an aspect of the present disclosure. Figures 15A-17C

[0084] Figure 19 is a perspective view of a front-loading pressure jacket retention mechanism according to an aspect of the present disclosure. Figures 15A-17C

[0085] Figures 20A-20C shows another embodiment of a front-loading pressure jacket retention mechanism with a syringe and pressure jacket in a closed position according to an aspect of the present disclosure. Figure 20A is a perspective view of the retention mechanism. Figure 20B is a side view of a linkage arrangement of the retention mechanism. Figure 20C is a cross-sectional view of the linkage arrangement.

[0086] Figures 21A-21C shows the front-loading pressure jacket retention mechanism in a second open position. Figures 20A-20C Figure 21A is a perspective view of the retention mechanism. Figure 21B is a side view of a linkage arrangement of the retention mechanism. Figure 21C is a cross-sectional view of the linkage arrangement.

[0087] Figures 22A-22C shows the front-loading pressure jacket retention mechanism in a first open position. Figures 20A-20C ​​​​​Front-loading pressure jacket retention mechanism, showing removal of syringe from pressure jacket. Figure 22A is a perspective view of the retention mechanism. Figure 22B is a side view of a linkage arrangement of the retention mechanism. Figure 22C is a cross-sectional view of the linkage arrangement. DETAILED DESCRIPTION

[0088] As used herein, the singular forms “a,” “an,” and “the” include plural referents unless the context clearly dictates otherwise.

[0089] Spatial or directional terms, such as “left,” “right,” “inner,” “outer,” “above,” “below,” and the like, relate to the invention as shown in the drawings and are not to be construed as limiting unless otherwise indicated. The drawings are for purposes of illustration only.

[0090] In all cases, all numerical values used in the specification and claims are to be understood as being modified in all instances by the term “about.” The term “about” means plus or minus 25% of the value stated, e.g., plus or minus 10% of the stated value. This is not to be construed as an exhaustive analysis of the numerical values.

[0091] Unless otherwise indicated, all ranges or ratios disclosed herein are to be understood to encompass both the stated limit values and any and all sub-ranges or sub-ratios therein. For example, a stated range or ratio of “1 to 10” should be considered to include any and all sub-ranges or sub-ratios of the minimum value of 1 and the maximum value of 10; that is, all sub-ranges or sub-ratios beginning with a minimum of 1 or more and ending with a maximum of 10 or less. The ranges and / or ratios disclosed herein represent the average values over the specified range and / or ratio.

[0092] The terms “first,” “second,” and the like, do not denote any particular order or chronology, but rather are used to distinguish different conditions, properties, or elements.

[0093] All documents mentioned herein are “incorporated by reference” in their entirety.

[0094] The term “at least” is synonymous with “greater than or equal to.”

[0095] The term “no more than” is synonymous with “less than or equal to.”

[0096] As used herein, “at least one of’ is synonymous with “one or more of.” For example, the phrase “at least one of A, B, and C” means any one of A, B, or C, or any combination of any two or more of A, B, or C. For example, “at least one of A, B, and C” includes A alone; or B alone; or C alone; or A and B; or A and C; or B and C; or all of A, B, and C.

[0097] The term "includes" is synonymous with "comprises."

[0098] The term "proximal" when used in relation to a syringe (e.g., a rolling diaphragm syringe) refers to the portion of the syringe closest to the piston element for engagement with the end wall of the syringe and delivery of fluid from the syringe. The term "proximal" when used in relation to a fluid path refers to the portion of the fluid path closest to the injector system when the fluid path is connected to the injector system. The term "distal" when used in relation to a syringe refers to the portion of the syringe closest to the delivery nozzle. The term "distal" when used in relation to a fluid path refers to the portion of the fluid path closest to the patient when the fluid path is connected to the injector system. The term "radial" refers to a direction in a cross-section normal to the longitudinal axis of the syringe extending between the proximal end and the distal end. The term "circumferential" refers to a direction around the inner surface or outer surface of the side wall of the syringe. The term "axial" refers to a direction along the longitudinal axis of the syringe extending between the proximal end and the distal end.

[0099] It should be understood, however, that the present disclosure is capable of employing alternative variants and sequences of steps, unless explicitly specified to the contrary. It should also be understood that the specific devices and processes illustrated in the attached drawings, and described in the following specification, are simply exemplary aspects of the present disclosure. Hence, specific dimensions and other physical characteristics related to the examples disclosed herein are not to be considered as limiting.

[0100] Referring to the drawings, wherein like reference characters are used throughout the several views to designate the same parts, the present disclosure relates generally to medical injector / injection systems 100 (hereinafter "fluid injector systems 100"), such as injection systems including one or more syringes, including front-loaded syringes and rolling diaphragm syringes. However, various methods and aspects of the present disclosure can be utilized or incorporated into other syringe-based injection systems.

[0101] Reference is made to Figure 1The fluid injector system 100 includes a number of components described individually herein. Generally, the fluid injector system 100 has a powered injector manager or device configured to move various components of the injector during an injection protocol and operated by at least one processor, and a fluid delivery set intended to be associated with the powered injector to draw and deliver one or more fluids under pressure from one or more fluid reservoirs into a patient. According to non-limiting embodiments, various devices, components, and features of the fluid injector system 100 and fluid delivery set associated therewith are likewise described in detail herein. In one example, the fluid injector system 100 can include at least one fluid reservoir (e.g., syringe 132), at least one piston (not shown) having an interface reversibly connectable to a plunger of the syringe, and a fluid control module (not shown). Embodiments and features of suitable syringes are described in U.S. Provisional Application Serial No. 63 / 073,519, filed September 2, 2020, the disclosure of which is incorporated herein by this reference. The at least one syringe 132 is generally adapted to interface with at least one component of the system, such as the syringe port 13 and / or the pressure jacket 134. The fluid injector system 100 is generally configured to deliver at least one fluid to a patient during an injection procedure, such as an angiographic injection procedure. The fluid injector system 100 is configured to releasably receive at least one syringe 132 to be filled with at least one fluid, such as an imaging contrast medium, a saline solution, Ringer’s lactate, or any desired medical fluid, supplied by a fluid source through a fluid line. The system can be a multiple syringe injector, where two or more syringes can be oriented side-by-side in other spatial relationships and individually actuated by respective pistons associated with the injector. The at least one syringe 132 can be oriented in any manner, such as upright, inverted, or positioned at any angle.

[0102] With continued reference to Figure 1The injector system 100 can be used to inject at least one medical fluid into a patient's vascular system during a medical procedure by actuating the plunger of at least one syringe 132 with a drive member (e.g., at least one piston (not shown)). At least one piston is reciprocating on at least a portion (e.g., the plunger) of at least one syringe 132. Upon engagement, at least one piston can move the plunger toward the distal end 140 of at least one syringe 132 and retract the plunger toward the proximal end of at least one syringe 132. The syringe 132 extends along a longitudinal axis. Fluid lines may also be fluidly connected to the outlet port of each syringe 132 to position each syringe 132 in fluid communication with a large-capacity fluid reservoir and / or catheter for filling each syringe 132 with medical fluid to deliver fluid from each syringe 132 to a catheter (not shown) inserted into the patient's body at a vascular access location.

[0103] In various examples, the syringe holding features of this disclosure are applicable to single-syringe or dual-syringe preloaded fluid injector systems, such as those disclosed in U.S. Patent Nos. 5,383,858, 7,553,294, 7,563,249, 7,666,169, 8,945,051, 9,173,995, 9,199,033, 9,474,857 and 10,124,110, U.S. Patent Application Serial Nos. 15 / 305,285, 15 / 541,573 and 15 / 568,505, and PCT Application Publications WO2016 / 19148, WO 2016 / 112163, and WO 2020 / 055785, the disclosures of which are incorporated herein by reference in their entirety.

[0104] refer to Figure 1 The fluid injector system 100 (also referred to as an "injector") includes an injector housing 102 having opposing lateral sides 104, a distal or upper end 106, and a proximal or lower end 108. The housing 102 encloses various mechanical drive components, electrical and power components required to drive the mechanical drive components, and control components (e.g., electronic memory and electronic control devices (hereinafter referred to as (a plurality of) electronic control devices)) to control the operation of the reciprocating piston element associated with the fluid injector system 100 described herein, including communication with a controller or processor.

[0105] refer to Figure 1Embodiments of the fluid injector system 100 may include one or more user interfaces 124 (such as a graphical user interface (GUI) display window or a touchscreen) and / or one or more buttons and readings. The user interface 124 may display information related to the fluid injection process involving the fluid injector system 100, such as the current flow rate, fluid pressure, and remaining volume in the fluid source 21 connected to the fluid injector system 100. In some embodiments, one or more user interfaces 124 may be at least one touchscreen GUI that allows an operator to input commands and / or data for operating the fluid injector system 100. While the user interface 124 is shown on the injector housing 102, the interface 124 may also be in the form of or include an additional remote display that is wired or wirelessly linked to the housing 102 of the fluid injector system 100 and electrical control devices and mechanical components. In some aspects, the user interface 124 may be a tablet computer detachably connected to and communicating with the housing 102 via a wired or wireless link. The fluid injector system 100 may also include one or more processors that are electronically in communication with and configured to control one or more functions of the fluid injector system 100. Additionally, the fluid injector system 100 and / or user interface 124 may include at least one control button 126 for tactile operation by a user of the fluid injector system 100, such as a button for engaging and disengaging the syringe holding feature described herein. In some aspects, the at least one control button 126 may be a portion of a keyboard for inputting commands and / or data by an operator. The at least one control button 126 may be hardwired or wirelessly connected to one or more electronic control devices associated with the fluid injector system 100 to provide direct input to the electronic control devices. The at least one control button 126 may also be a graphical portion of the user interface 124, such as a touchscreen. In any arrangement, at least one control button 126 is intended to provide certain individual control features to the operator of the fluid injector system 100, such as, but not limited to: (1) filling / infusing the fluid injector system 100; (2) inputting information and / or data related to the patient and / or the injection process; and (3) starting / stopping the injection process. The user interface 124 and / or any electronic processing unit associated with the fluid injector system 100 may be wired or wirelessly connected to an operating and / or data storage system, such as a hospital network system.

[0106] As used herein, electronic control devices include processors that execute or are operable to execute appropriate custom-designed or conventional software to perform and implement processing steps of embodiments of the methods and systems of this disclosure, thereby forming a dedicated and specific computing system. Therefore, the methods and systems currently disclosed may comprise one or more electronic control devices or similar computing devices having a computer-readable storage medium capable of storing computer-readable program code or instructions that cause processor units to execute, configure, or otherwise implement the methods, processes, and data manipulations discussed herein in conjunction with this disclosure. Furthermore, electronic control devices may be in the form of computers, personal digital assistants, portable computers, laptop computers, handheld computers, mobile devices, mobile phones, servers, or any other type of computing device having the processing hardware necessary to appropriately process data to efficiently implement the computer-implemented methods and systems of this disclosure. In one example, the electronic control device may be housed in a user interface 124 and a corresponding processor.

[0107] This disclosure relates to syringes and pressure sheath retention features specifically for angiography (CV) injectors. Contrast-enhanced angiography involves injecting fluid into the heart via a catheter. Due to the viscosity and high flow rate of contrast agents and the small diameter of the catheter, angiography injections can involve high pressures up to 1200 psi. At such high pressures, conventional plastic syringes used in contrast-enhanced computed tomography scans, including pressures up to 300 psi, may experience excessive radial expansion of the syringe wall, which can lead to undesirable changes in fluid delivery volume and flow rate, or even potentially cause structural failure. To address this problem, pressure sheaths with thicker or more robust material walls have been developed to limit the radial expansion of the pressurized syringe. The CV injector must be designed to engage and retain not only with the syringe but also with a corresponding pressure sheath surrounding at least a portion of the sidewall of the syringe. This disclosure describes various embodiments of retention mechanisms for engaging the pressure sheath and / or syringe with the CV fluid injector.

[0108] For example, according to various embodiments, this disclosure describes an assembly for retaining a pressure sheath and a syringe on a CV fluid injector. The syringe and pressure sheath may be abutted against a substrate of the fluid injector, wherein the substrate may include a body. The assembly may include one or more retaining arms that project distally from the substrate and have retaining surfaces at their distal ends for abutting and engaging the distal ends of the pressure sheath and / or the syringe. In some embodiments, the assembly may include at least a first retaining arm and a second retaining arm operably mounted on the body of the substrate. The first retaining arm may have a first retaining surface at its distal end, and the second retaining arm may have a second retaining surface at its distal end, wherein the first and second retaining surfaces are configured to abut the distal surfaces of at least one of the pressure sheath and the syringe. The assembly may also include a linkage assembly operably connected to one or both of the first and second retaining arms. The linkage assembly may be configured to move at least one of the first and second retaining arms between at least a first open position and a closed position. The first and second retaining arms may each include at least one (and in some embodiments, two) longitudinal supports connecting opposite sides of the substrate to opposite sides of corresponding retaining surfaces. The two first longitudinal supports of the first retaining arm may be connected and move cooperatively about a commonly aligned first pivot point. The two second longitudinal supports of the second retaining arm may be connected and move cooperatively about a commonly aligned second pivot point.

[0109] In some embodiments, the linkage assembly is operatively connected to the proximal ends of the first retaining arm and the second retaining arm. For example, the linkage assembly may be operatively connected to the first retaining arm such that the first and second retaining arms are configured to move co-currently between at least a first open position and a closed position. Alternatively, the linkage assembly may be operatively connected to the first retaining arm such that the first and second retaining arms are configured to move independently between at least a first open position and a closed position. In some embodiments, the first and second retaining arms are connected to the body of the substrate at a first pivot point and a second pivot point, respectively, such that the first and second retaining arms pivot about the first and second pivot points between at least a first open position and a closed position.

[0110] In the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance being configured to allow insertion and engagement of at least one of the pressure sheath and the syringe with or from the fluid injector. In some embodiments, in the first open position, the distance between the first and second retaining surfaces may be wide enough to allow insertion and engagement of the syringe into and from the pressure sheath and retaining assembly, but not to allow insertion / engagement of the pressure sheath into / from the retaining assembly or removal of the pressure sheath from the retaining assembly. In other embodiments, in the first open position, the distance between the first and second retaining surfaces may be wide enough to allow insertion and engagement of the syringe into and from the pressure sheath and retaining assembly, and the distance between the first and second retaining surfaces may also be wide enough to allow insertion / engagement of the pressure sheath into / from the retaining assembly and removal of the pressure sheath from the retaining assembly during insertion / removal of the syringe or in separate operations.

[0111] In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm may be separated from each other by a second distance to retain the pressure sheath and syringe between the first and second retaining arms. For example, in the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm may be positioned such that the first retaining surface is adjacent to the second retaining surface to retain the syringe and pressure sheath within the retaining assembly, for example, during pressurized fluid delivery. In some embodiments, the first and second retaining surfaces may be arcuate or semi-circular in shape, and when in the closed, adjacent position, at least partially circular retaining surfaces may be formed to engage and retain the distal end of the syringe and the distal end of the pressure sheath. According to various embodiments, the first distance between the first and second retaining arms may be greater than the second distance.

[0112] In various embodiments, the first retaining arm and the second retaining arm are pivotable about a first pivot point and a second pivot point between at least an intermediate second open position. In the second open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a third distance to retain the pressure sheath in the fluid injector and allow the syringe to be inserted into and removed from the pressure sheath, and to engage and disengage the syringe from the fluid injector. Specifically, in the second open position, the distance between the first retaining surface and the second retaining surface may be wide enough to allow the syringe to be inserted into and engaged in the pressure sheath, and to remove the syringe from the pressure sheath and the retaining assembly, but not to allow the pressure sheath to be inserted into / engaged in the retaining assembly or to be removed from the retaining assembly. According to these embodiments, the first distance in the first position is greater than the second distance, and the third distance is less than the first distance and greater than the second distance.

[0113] In various embodiments, the first retaining surface of the first retaining arm includes a first syringe retaining surface and a first pressure sheath retaining surface, and the second retaining surface of the second retaining arm includes a second syringe retaining surface and a second pressure sheath retaining surface. The first syringe retaining surface and the second syringe retaining surface and / or the first pressure sheath retaining surface and the second pressure sheath retaining surface may include one or more protrusions for engaging the syringe and / or the pressure sheath, respectively.

[0114] In some embodiments, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm may each include at least one inner protrusion to engage the distal end of at least one of the pressure sheath and the syringe. In some embodiments, the first and second retaining surfaces include an inner syringe retaining protrusion to engage a circular support wall at the distal end of the syringe. The syringe retaining protrusion may be at least partially circumferential and extend proximally from each retaining surface, and include a proximal surface angled relative to the longitudinal axis of the syringe, and having at least an innermost partial circumference extending proximally beyond the outermost at least partial circumference, thereby creating an angled proximal surface. This angled proximal surface may be configured to interact with a corresponding, oppositely angled surface of the circumferential support wall at the distal end of the injector. The complementary angled surfaces interact under distally directed pressure on the syringe associated with the fluid injection process to push the distal ends of the first and second retaining arms with an inward retaining force. In other words, when the syringe is pressurized, the angled surface of the syringe circumferential bearing wall is pushed in the distal direction and generates an inward radial force on the corresponding complementary angled surface of the syringe retaining protrusion, so as to push the first retaining surface and the first retaining arm toward the second retaining surface and the second retaining arm with the inward retaining force, thereby helping to keep the first retaining arm and the second retaining arm in the closed position under fluid injection pressure.

[0115] According to various embodiments, a first retaining surface of the first retaining arm and a second retaining surface of the second retaining arm may each include at least one pressure sheath protrusion to engage a distal end of the pressure sheath. For example, the pressure sheath protrusion may form a circumferential groove in the proximal surface of the first and second retaining surfaces, the circumferential groove interacting with the distal end of the pressure sheath to provide a slot in which the distal end of the pressure sheath can be inserted and retained. The first and second retaining surfaces may include one or more engaging slots, tabs, or other features that interact with corresponding tabs, slots, or features on the distal end of the pressure sheath to engage and retain the pressure sheath when the retaining assembly is in the closed position, for example, preventing the pressure sheath from sliding laterally and misaligning with the engaging arm.

[0116] According to various embodiments, the linkage assembly may include at least one biasing member configured to bias a first retaining arm and a second retaining arm to move coherently between at least a first open position and a closed position (and in some embodiments, between intermediate second open positions). The biasing member may include a plurality of biasing members (e.g., springs) that bias the first retaining arm to the first open position and may work with a first biasing plate to bias the first retaining arm to the closed position. Similarly, the second retaining arm may include more than one biasing member (e.g., springs) that bias the second retaining arm to the first open position and may work with a second biasing plate to bias the first retaining arm to the closed position.

[0117] According to various embodiments, at least one of the first and second retaining arms may include at least one finger, configured to assist movement of the first and second retaining arms between a closed position and a first and / or a second open position. One or more fingers may be arranged on the first and second retaining arms to allow a user to manually open and / or close the first and second retaining arms, such that the syringe and / or pressure sheath can be inserted into or removed from the retaining assembly. In some embodiments, each longitudinal support of the first and second retaining arms may each include one finger.

[0118] In other embodiments, the component and / or fluid injector may include an electromechanical motor disposed in the injector housing to move a first retaining arm and a second retaining arm between a first open position and a closed position. According to a specific embodiment, the electromechanical motor may further move the first and second retaining arms to an intermediate second open position.

[0119] Figure 2A and 2BA retaining element 600 according to various embodiments is shown, which is attached to the central support 602 of the CV fluid injector 604 by a hinge mechanism 606, which is available in an open position. Figure 2B ) and closing position ( Figure 2A The retaining element 600 can move between the open and closed positions. In the open position, at least one syringe 608 can be inserted into the pressure sheath assembly 610, and in the closed position, at least one syringe 608 is held securely within the pressure sheath assembly 610 for use in the fluid delivery process. In various embodiments, the retaining element 600 may include a rotatable plate member that can rotate between the open and closed positions. The retaining element 600 may be locked in the closed position using a snap-fit ​​feature 612 to prevent the retaining element 600 from moving to the open position during use of the CV fluid injector 604. In various embodiments, other locking mechanisms may be utilized to hold the retaining element 600 in the closed position.

[0120] Figure 3A and 3B A retaining element 700 according to various embodiments is shown, wherein the retaining element 700 includes two or more arms 702a, 702b, which are attached to the central support 704 of the CV fluid injector 706 via a pivoting mechanism 708. The retaining element 700 can be in an open position ( Figure 3B ) and closing position ( Figure 3A The pivoting mechanism 708 can move between the pressure sheath assembly 712 and the pressure sheath assembly 712. In the open position, at least one syringe 710 can be inserted into or removed from the pressure sheath assembly 712. In the closed position, at least one syringe 710 is held securely within the pressure sheath assembly 712 for fluid delivery. The pivoting mechanism 708 can be manually actuated by an operator (e.g., by moving a lever or other actuation component) or can be moved automatically by a motor assembly (not shown). The pivoting mechanism 708 is configured such that in the closed position, the retaining element 700 generates a clamping force and a downward force on the distal ends of one or both of the syringe 710 and the pressure sheath assembly 712 to prevent movement of one or both of the syringe 710 and the pressure sheath assembly 712 during operation of the CV fluid injector 706.

[0121] Figure 4A , Figure 4B and Figure 4C A retaining element 800 according to an embodiment is shown, which is connected to... Figure 3A and Figure 3B The retaining element is similar, wherein the retaining element 800 includes two or more arms 802a, 802b, which are attached to the central support 804 of the CV fluid injector 806 via a pivoting mechanism 808. The retaining element 800 can be in a first open position ( Figure 4C(Top view in the middle), second open position ( Figure 4B ) and closing position ( Figure 4A The pivoting mechanism 808 can move between the following positions: in a first open position, at least one syringe 810 and pressure sheath assembly 812 can be inserted into or removed from the assembly; in a second open position, at least one syringe 810 can be inserted into or removed from the pressure sheath assembly 812; and in a closed position, at least one syringe 810 and pressure sheath assembly 812 are fixedly held within the retaining element 800 for fluid delivery. The pivoting mechanism 808 can be manually actuated by an operator or can be moved automatically by a motor assembly (not shown). The pivoting mechanism 808 is configured such that in the closed position, the retaining element 800 generates a clamping force and a downward force on the distal ends of one or both of the syringe 810 and pressure sheath assembly 812 to prevent one or both of the syringe 810 and pressure sheath assembly 812 from moving during operation of the CV fluid injector 806. Figure 4A , 4B Implementation examples of 4C and Figure 3A and 3B The difference in the embodiments is at least that the two or more arms 802a, 802b pivot to allow the syringe 810 and / or pressure sheath assembly 812 to be inserted into or removed from the fluid injector 806 a certain distance.

[0122] Figure 5A and 5B An embodiment of a retaining element 900 for a CV application is shown, according to various embodiments, the retaining element 900 having a rotatable pressure sheath 902 on a rotatable retainer assembly 906. Figure 5A In this configuration, a portion of the retaining arm 904 of the retaining sleeve 902 and the syringe assembly 908, and the retainer assembly 906, rotate about corresponding pivot points 905, 910 to allow the pressure sleeve 902 and the syringe assembly 908 to be inserted into and removed from the retaining clamp. Figure 5A As shown, the retaining arm 904 and the retainer assembly 906 can pivot in opposite directions. Figure 5B In this embodiment, a retainer assembly holding the pressure sheath 902 and syringe 908 rotates the syringe 908 and pressure sheath 902 to engage and disengage with the fixed retaining surface of the retaining element 900. The retainer assembly 906 is independently rotatable relative to the CV fluid injector 912 to move the syringe 908 and pressure sheath 902 away from and towards the CV fluid injector 912. When the retainer assembly 906 rotates to the mating position (e.g., ...), Figure 5BWhen (shown on the right-hand side), the retaining arm 904 can rotate to engage the syringe 908 and pressure sheath 902 in the retainer assembly 906 to retain the syringe 908 and pressure sheath 902 within the CV fluid injector 912. The retaining arm 904 may include one or more elements for retaining the syringe 908 and pressure sheath 902 assembly. The retainer assembly 906 can be manually moved (e.g., using arm 910) to pivot the retainer assembly 906 between open and closed positions. Alternatively, a motor associated with the fluid injector 912 can be used to move the retainer assembly 906 between open and closed positions.

[0123] Figures 6A-6E An embodiment of a retaining element 1000 for a post-loaded CV application with a syringe 1002, according to various embodiments, is shown. Compared to conventional injectors based on pre-loaded syringes, according to this embodiment, the syringe 1002 is loaded into a pressure sheath 1004 via a post-loading mechanism 1006, wherein the proximal end of the pressure sheath 1004 faces upward (see...). Figure 6B and 6C Alternatively, it may pivot downwards to allow at least one syringe 1002 to be inserted into the proximal end of the pressure sheath 1004. Subsequently, the pressure sheath 1004 pivots back to the plane of the injector 1008 (see...). Figure 6D ), and is locked in place by locking mechanism 1010 (see Figure 6E This allows the fluid injector piston to engage the syringe 1002. In some embodiments, the pressure sheath 1004 may include a distal cap (not shown) whose shape is complementary to the distal end of the syringe 1002. For example, the distal cap may be conical to engage the conical distal end of the syringe 1002. The cap may be integral with the pressure sheath 1004 or may be attached to the distal end of the pressure sheath 1004. In other embodiments, the distal cap may be mounted on the distal end of the syringe 1002 before being inserted into the notch of the pressure sheath 1004, such that the outer circumference of the distal cap engages an inner boss on the inner surface of the distal end of the pressure sheath 1004.

[0124] Figures 7A-7D An embodiment of a CV fluid injector 1100 according to various embodiments is shown, the CV fluid injector 1100 having a front-loaded configuration with a sliding retaining element 1102. The sliding retaining element 1102 is configured upward relative to the longitudinal axis of the pressure sheath 1104 (see figure). Figure 7A ) or down (see Figure 7D Slide to allow access to the distal end of the pressure sheath 1104, so that the syringe 1106 can be inserted into or removed from it (see...). Figure 7B and 7CAfter the syringe is inserted, the sliding retaining element 1102 slides into the closed position and locks in place to hold the syringe 1106 in the pressure sheath 1104 (see...). Figure 7D Then, the fluid line component 1108 can be attached to the fluid outlet at the distal end of the syringe 1106.

[0125] Figures 8A-8E A fixed retaining element 1202 is shown according to various embodiments (see Figure 8A ) and two-piece pressure sleeve 1204 (see Figure 8E An embodiment of the CV fluid injector 1200. According to this embodiment, the upper portion 1206 of the pressure jacket 1204 can be removed, and the fluid path component 1208 and the valve are installed. Figure 8B And the syringe 1210 is inserted into the lower pressure sheath assembly 1212. Figure 8C and 8D The upper part 1206 of the pressure sleeve 1204 can then be reinstalled. Figure 8E The system is prepared for a fluid delivery process, for example, by attaching the fluid path component 1208. The upper portion 1206 of the pressure sheath 1204 may engage the retaining surface at the distal end of the lower pressure sheath assembly 1212 and the engagement feature on the port of the fluid injector 1200, for example, when the syringe is pressurized and pushed in the distal direction by the piston.

[0126] Figure 9A and 9B Examples of rotating retaining elements 1300 for allowing access to a pressure sheath / injector assembly 1310 of a CV fluid injector 1302 having a hinged pressure sheath retaining feature 1304, according to various embodiments, are shown. Figure 9A The retaining member / pressure sleeve assembly 1304 is shown in the closed and locked positions. Figure 9B In the middle, the retaining member / pressure sheath assembly 1304 is shown in the open position, wherein the top plate 1306 of the assembly 1304 is rotated up to 90 degrees and the pressure sheath cover 1308 is pivotally hinged to access the pressure sheath / injector assembly 1310 for insertion or removal.

[0127] Figure 10A and 10B An embodiment of a retaining element 1400 for a CV fluid injector 1402 according to various embodiments is shown. The CV fluid injector 1402 has a pressure sheath 1404 on a rotatable plate 1406. The pressure sheath and injector assembly 1408 are held on the rotatable proximal plate 1406, which is in a closed position ( Figure 10A ) and opening position ( Figure 10BThe pressure sheath and syringe assembly 1408 can be rotated between the closed and open positions. In the closed position, the distal end of the pressure sheath and syringe assembly 1408 engages with the distal retaining plate 1410. In the open position, the proximal plate 1406 can be rotated up to 90 degrees to disengage the pressure sheath and syringe assembly 1408 from the distal retaining plate 1410. After being rotated to the open position, the pressure sheath and syringe assembly 1408 can be inserted into or removed from the CV fluid injector 1402.

[0128] Figures 11A-11I An embodiment of a fluid injector head with a rear-loaded pressure sheath and a rotating pressure sheath engagement arm 1500 is shown. The pressure sheath engagement arm 1500 includes an opening 1502 through which a pressure sheath 1504 can be loaded when the pressure sheath engagement arm 1500 is loaded. The pressure sheath engagement arm 1500 may include a pressure sheath retaining mechanism (e.g., see...). Figure 13A -E and 14A-F), to releasably retain the pressure sleeve 1504 within the pressure sleeve engagement arm 1500. The pressure sleeve engagement arm 1500 can be rotated around a pivot point 1506 (see...). Figure 11B From the open position ( Figure 11A (As shown) Rotate to the engagement position ( Figure 11C (As shown). The rotating pressure sheath engagement arm 1500 can be rotated manually by the user, or it can be rotated automatically by the fluid injector operating system, for example, after the user presses a button or other actuation mechanism on the fluid injector system or after the fluid injector senses that the syringe 1508 is already in the pressure sheath 1504. In other embodiments, the pressure sheath engagement arm 1500 can slide between an open position and an engaged position.

[0129] In the open position, syringe 1508 can be inserted into pressure sheath 1504 via a post-loading process, see... Figure 11A As used herein, the term "reloading" refers to inserting the syringe 1508 into the proximal open end of the pressure sheath 1504, such as... Figure 11AAs indicated by arrow A, for example, until the distal tip of syringe 1508 and the fluid delivery port protrude from the distal opening of pressure sheath 1504. According to these embodiments, pressure sheath 1504 may include circumferential sidewalls with an inner diameter slightly larger than the outer diameter of the sidewall of syringe 1508, and may include a partially closed distal end having an inner wall covering a portion of the distal end of pressure sheath 1504, and having an inner surface with a shape complementary to the shape of the outer surface of the distal end of syringe 1508. For example, in one embodiment, the distal ends of pressure sheath 1504 and syringe 1508 may have complementary conical distal ends. In other embodiments, a portion of the distal end of syringe 1508 may include an outer surface perpendicular to the longitudinal axis of syringe 1508, the outer surface engaging the inner surface of the distal end of pressure sheath 1504, the inner surface being perpendicular to the longitudinal axis of pressure sheath 1504. Once syringe 1508 is loaded into pressure sheath 1504, pressure sheath engagement arm 1500 can be... Figure 11B Rotate to the direction indicated by arrow B in the diagram. Figure 11C The engagement position. The pressure sleeve engagement arm 1500 can be held in the engagement position, for example by means of a latching mechanism or a pawl mechanism 1510.

[0130] Figure 11D A front view of a fluid injector pressure sheath retaining mechanism 1500 in an engaged position, according to an embodiment of the present disclosure, is shown. Figure 11E A cross-sectional side perspective view of line AA along the operation of a fluid injector carrier according to one embodiment is shown.

[0131] according to Figures 11A-11I The illustrated embodiment, when the pressure sheath engagement arm 1500 is in the engaged position during the filling or injection process, the assembly may include three bracket positions. When in the engaged position, various features of the interface between the fluid injector port 1512 and the rotary pressure sheath engagement arm 1500 are... Figure 11F The cross-sectional view is shown. The interface features include a bracket on the axial slide 1514, a pawl or latch 1510 for releasably locking the pressure sheath engagement arm 1500 in the engagement position, a plunger interface 1518 attached to a ball screw or other drive mechanism via a piston, a frame 1520 on the proximal end of the fluid injector, a pressure sheath 1504, and a syringe 1508 within the pressure sheath 1504.

[0132] The operation of these features is shown in Figure 11G , 11H The three bracket positions are shown in 11I. Figure 11GIn this configuration, the pawl or latch 1510 is initially in the disengaged position to allow the pressure sheath engagement arm 1500 to rotate from the open position to the engaged position. To facilitate rotation to the engaged position, the fluid injector bracket assembly 1514 is in the first disengaged position, and a gap exists between the rotating pressure sheath engagement arm 1500 and the fluid injector frame 1520. Figure 11H As shown, the gap between the bracket assembly 1514 and the pressure sheath / syringe feature with the pressure sheath engagement arm 1500 results in mechanical loosening between the injector, pressure sheath 1504, and syringe 1508 components. Once the pressure sheath engagement arm 1500 is in the engaged position, the user can lock the pressure sheath engagement arm 1500 in the engaged position by actuating the pawl or latch 1510 to the locked position, thereby locking the pressure sheath engagement arm 1500 in the engaged position as shown. Figure 11H The engagement position is shown. The pawl or latch 1510 can be operated by a screw mechanism, solenoid, or other motor to move distally and lock the pawl pin into the corresponding hole in the pressure sheath engagement arm 1500. Alternatively, the user can latch or manually lock the pawl or latch 1510 to the locked position. Although the pawl / latch 1510 is now in the engaged position, the fluid injector bracket assembly 1514 remains in the first disengaged position and also maintains the clearance between the rotating pressure sheath engagement arm 1500 and the fluid injector frame 1520. Figure 11IThe movement of the carriage 1514 to the locked and operating position is illustrated. The carriage 1514 is moved in the distal direction, for example by a spring or other biasing member or by a motor such as that associated with the piston of the fluid injector. For example, in one embodiment, the carriage 1514 may be moved distally by a ball screw connected to the piston interface or other electric component. When the carriage 1514 is moved to the locked and operating position, the distal surface of the carriage 1514 seats the syringe 1508 in the pressure sheath 1504 by abutting the proximal end of the syringe 1508 and pushing it distally. Furthermore, as the carriage 1514 moves distally, the proximal circumferential flange of the pressure sheath 1504 abuts against the pressure sheath engagement arm 1500, and the distal surface of the pressure sheath engagement arm 1500 is seated against the fluid injector frame 1520. When the system is in the locked and operating position, the mechanical relaxation associated with syringe 1508, pressure sheath 1504, and piston is reduced and taken into account, thereby limiting the compliance associated with the fluid injection system and resulting in a more precise injection volume. In embodiments that include a spring-loaded or otherwise distally biased carriage 1514, the spring force or biasing force is sufficient to prevent proximal movement of syringe 1508 and / or pressure sheath 1504 during syringe loading operations. Furthermore, during syringe loading operations, the spring force or biasing force should be sufficient to overcome the spring force when the pressure sheath engagement arm 1500 pushes the arm back. In some embodiments that include a spring biasing force distally biasing the carriage 1514, the proximal retraction piston will retract the carriage 1514 proximally against the spring biasing force, thereby allowing the pressure sheath engagement arm 1500 to automatically open in response to a second torsion spring associated with the pressure sheath engagement arm 1500. In various embodiments, the bracket latching mechanism may be integrated into the fluid injector to prevent (e.g., in the event of a power failure) remote movement of the bracket 1514, thereby preventing the interface from accidentally locking in the locked and delivery position.

[0133] Figures 12A-12H Another embodiment of a fluid injection head with a post-loaded pressure sheath and a rotating pressure sheath engagement arm 1600 is shown. The pressure sheath engagement arm 1600 includes an opening through which a pressure sheath 1602 can be loaded when the pressure sheath engagement arm 1600 is loaded. The pressure sheath engagement arm 1600 may include a pressure sheath retaining mechanism 1604 (e.g., see Figures 13 and 14) to releasably retain the pressure sheath 1602 within the pressure sheath engagement arm 1600. The rotating pressure sheath engagement arm 1600 can be rotated about a pivot point 1606 (see Figure 1606). Figure 12C From the open position ( Figure 12A (As shown) Rotate to the engagement position ( Figure 12C(As shown). The rotating pressure sheath engagement arm 1600 can be manually rotated by a user using the user engagement handle 1610 on the pressure sheath engagement arm 1600, or it can be automatically rotated by the fluid injector operating system, for example, after the user presses a button or other actuation mechanism on the fluid injector system or after the fluid injector senses that the syringe 1612 is already in the pressure sheath 1602. In other embodiments, the pressure sheath engagement arm 1600 can slide between an open position and an engaged position.

[0134] In the open position, syringe 1612 can be loaded into pressure sheath 1602 via a post-loading process, as described herein. Figure 12A Insert syringe 1612 into the proximal open end of pressure sheath 1602, as follows. Figure 12A As indicated by arrow A, for example, until the distal tip of syringe 1612 and the fluid delivery port protrude from the distal opening of pressure sheath 1602. Once syringe 1612 is loaded into pressure sheath 1602, pressure sheath engagement arm 1600 can be engaged as follows: Figure 12B Rotate to the direction indicated by arrow B in the diagram. Figure 12C The engagement position. The pressure sheath engagement arm 1600 can be held in the engagement position, for example, by a latching mechanism or a pawl mechanism 1614.

[0135] Figure 12D A front view of the fluid injector pressure sheath retaining mechanism in the engaged position according to an embodiment of the present disclosure is shown. Figure 12E A cross-sectional side perspective view of the fluid injector carrier operating along line BB according to one embodiment is shown.

[0136] according to Figures 12A-12H In the illustrated embodiment, during the filling or injection process, when the pressure sheath engagement arm 1600 is in the engaged position, the assembly may include two bracket positions. When in the engaged position, various features of the interface between the fluid injector port and the rotating pressure sheath engagement arm 1600 are present. Figure 12F The cross-sectional view is shown. The interface features include a bracket on the axial slide 1616, a biased pawl or latch 1614 for releasably locking the pressure sheath engagement arm 1600 in the engagement position, a plunger interface 1618 attached to a ball screw or other drive mechanism via a piston, a frame 1620 on the proximal end of the fluid injector, a pressure sheath 1602, and a syringe 1612 within the pressure sheath 1602.

[0137] The operation of these features is shown in Figure 12G and 12H The two bracket positions are shown. Figure 12GIn this process, rotation of the pressure sheath engagement arm 1600 from the open position to the engaged position moves the bias pawl or latch 1614 to the engaged position. To facilitate rotation to the engaged position, the fluid injector bracket assembly 1616 is in a first disengaged position, and a gap exists between the rotating pressure sheath engagement arm 1600 and the fluid injector frame 1620, such as... Figure 12G As shown, this results in mechanical slack between the injector components, pressure sheath 1602, and syringe 1612, and allows the pressure sheath engagement arm 1600 to move once the biasing force of the pawl or latch 1614 is overcome. While the pawl / latch 1614 is now in the engaged position, the fluid injector carrier assembly 1614 remains in the first disengaged position, and also maintains the clearance between the rotating pressure sheath engagement arm 1600 and the fluid injector frame 1620. Figure 12HThe diagram illustrates the movement of the carriage 1614 to the locked and operating position. The carriage 1614 (e.g., by means of a spring or other biasing member, or by means of a motor such as a ball screw connected to a piston interface or other electrical component associated with the piston of the fluid injector) moves in the distal direction. As the carriage 1614 moves to the locked and operating position, the distal surface of the carriage 1614 seats the syringe 16112 in the pressure sheath 1602 by abutting the proximal end of the syringe 1612 and pushing it in the distal direction. Furthermore, as the carriage 1614 moves in the distal direction, the proximal circumferential flange of the pressure sheath 1602 abuts against the pressure sheath engagement arm 1600, and the distal surface of the pressure sheath engagement arm 1600 abuts against the fluid injector frame 1620. According to an embodiment, once the fluid injector is in the locked and operating position, the pawl or latch 1614 can be moved to the unlocked position. Alternatively, the pawl 1614 can remain in a bias-locked position whenever the pressure sheath engagement arm 1600 is in the closed position. When the system is in the locked and operating position, the mechanical relaxation associated with the syringe 1612, pressure sheath 1602, and piston is reduced and taken into account, thereby limiting the compliance associated with the fluid injection system and resulting in a more precise injection volume. In embodiments including a spring-loaded or otherwise distally biased pawl 1614, the spring force or biasing force is sufficient to prevent proximal movement of the syringe 1612 and / or pressure sheath 1602 during the filling operation of the syringe 1612. Furthermore, during the syringe loading operation, the spring force or biasing force should be sufficient to overcome the spring force when the pressure sheath engagement arm 1600 pushes the arm back. In some embodiments, including a spring biasing force that biases the bracket 1614 distally, the proximal retraction piston will retract the bracket 1614 proximally against the spring biasing force, thereby allowing the pressure sheath engagement arm 1600 to open automatically in response to a second torsion spring associated with the pressure sheath engagement arm 1600. Alternatively, a user can manually rotate the pressure sheath engagement arm 1600 back to the open position by grasping the handle 1610 and rotating the arm 1600 outward. In various embodiments, a bracket latching mechanism may be integrated into the fluid injector to prevent (e.g., in the event of a power failure) distal movement of the bracket 1614, thereby preventing the interface from accidentally locking in the locked and delivery position.

[0138] Figures 13A-13E An embodiment of a pressure sheath retaining mechanism 1700 is shown, which can be used with embodiments of a post-loaded fluid injector system. The pressure sheath retaining mechanism 1700 ensures that the pressure sheath 1702 is securely held in the pressure sheath engaging arm 1704 while allowing the pressure sheath 1702 to be removed, for example, for cleaning or replacement. Figure 13AA proximal perspective view of a pressure sheath 1702 held in a pressure sheath retaining mechanism 1700 in an engaging arm 1704 according to one embodiment is shown. The pressure sheath 1702 may include a circumferential flange 1706 at the proximal end of a sidewall of the pressure sheath. The outer circumference of the circumferential flange 1706 may have a sloped surface, the sloped surface having a larger diameter at the distal edge of the flange 1706 relative to the proximal edge, see [reference needed]. Figure 13B The inclined circumferential flange 1706 can be used to retain the pressure sleeve 1702 within the mechanism 1700. For example... Figure 13B As shown, the pressure sleeve 1702 is back-loaded into the receiving opening of the engagement arm 1704 at the angle indicated by arrow A. On one side of the receiving opening, an inner lip engages the side of the inclined circumferential flange 1706. The pressure sleeve 1702 can then be... Figure 13C Rotate in a circular motion as indicated by arrow B until pressure sleeve 1702 is reached. Figure 13D As shown, it is seated in the receiving opening. When the pressure sheath 1702 is seated, as... Figure 13D As shown, the other side of the inclined circumferential flange 1706 engages with a biased pawl or latch 1708 on the inner surface of the receiving opening, which holds the pressure sheath 1702 within the receiving opening of the pressure sheath engaging arm 1704, as... Figure 13E As shown. By reversing these steps, the pressure sleeve 1702 can be removed from the pressure sleeve engagement arm 1704.

[0139] Figures 14A-14F Another embodiment of the pressure sheath retaining mechanism 1800 is shown, which can be used with embodiments of a post-loaded fluid injector system that uses a bayonet-type retaining mechanism. Figure 14A A proximal perspective view of a pressure sheath 1802 held in a pressure sheath retaining mechanism 1800 of an engaging arm 1804 according to one embodiment is shown. The pressure sheath 1802 may include a circumferential flange 1806 at the proximal end of the pressure sheath sidewall. The outer circumference of the circumferential flange 1806 includes a retaining groove, such as a standard bayonet-type retaining groove 1808 (see [link to relevant documentation]). Figure 14E ) or latching bayonet type groove 1810 (see Figure 14F The groove on the circumferential flange 1806 interacts with the corresponding engaging pin 1812 on the inner surface of the opening of the pressure sleeve retaining arm 1804, as... Figure 14A As shown. Figure 14B As shown, the pressure sleeve 1802, as indicated by arrow A, is subsequently loaded into the receiving opening of the engagement arm 1804, in which orientation is maintained such that the lateral portion of the groove is aligned with the engagement pin 1812 on the engagement arm 1804 until the circumferential flange 1806 of the pressure sleeve abuts the corresponding flange of the opening, as shown. Figure 14CAs shown. Once the pressure sleeve 1802 is loaded and the lateral portion of the retaining groove has engaged the pin 1812, the pressure sleeve 1802 can then be rotated clockwise or counterclockwise (as shown). Figure 14D (As indicated by arrow B in the diagram), to engage pin 1812 with the portion of the groove perpendicular to the transverse axis during bayonet locking. Figure 14E An embodiment of a retaining groove 1808 is shown for retaining the pin and thus keeping the pressure in place. Figure 14F Another embodiment of the latch recess 1810 is shown, which is used to latch the pin 1812 through a recess having a recess for receiving the pin 1812, thereby latching the pressure sleeve 1802 in place.

[0140] refer to Figures 15A-17C This illustration shows a pressure sheath and syringe retainer assembly 1900 according to another example or aspect of this disclosure. The pressure sheath and syringe retainer assembly 1900 may include a substrate 1902 operatively connected to an injector housing, for example... Figure 1 The injector housing 102 of the fluid injector system 100 shown. Figure 1 The fluid injector system 100 may include one or more pressure sheaths and syringe retaining assemblies 1900, depending on the number of syringes to be attached. According to various embodiments, Figure 1 The fluid injector system 100 may include two or more pressure sheaths and syringe holding assemblies 1900 to hold two or more syringes. The base plate 1902 may include a body 1904 for supporting components of the pressure sheaths and syringe holding assemblies 1900. According to various embodiments, the base plate 1902 may be operatively connected to or attached to the fluid injector system, for example… Figure 1 The fluid injector system 100 shown may be integrally formed with the fluid injector system. A base plate 1902 may hold a pressure sleeve 1906, which is configured to receive and hold a syringe 1908. The pressure sleeve 1906 may be pre-installed in the pressure sleeve and syringe holding assembly 1900 such that only the syringe 1908 can be inserted into or removed from the pressure sleeve 1906, or it may be inserted / replaced after the pressure sleeve and syringe holding assembly 1900 is assembled.

[0141] The pressure sheath and syringe retaining assembly 1900 may further include at least two retaining arms 1910a, 1910b, which are operatively connected to the base plate 1902 and are used to retain the syringe 1908 in the pressure sheath 1906 and to retain the pressure sheath 1906 on the fluid injector. Each retaining arm 1910a, 1910b may include at least two base members or support arms 1912a, 1912b, 1912c, 1912d, which are pivotally connected to the base plate 1902 at corresponding pivot points 1914a, 1914b. The base components 1912a, 1912b, 1912c, and 1912d can be configured to rotate toward and away from the pressure sheath 1906 and the syringe 1908 between an open position and a closed position. In the open position (e.g., Figures 17A-17C As shown, retaining arms 1910a and 1910b can be separated from each other by a first distance, which allows the pressure sheath 1906 and syringe 1908 to be inserted between the retaining arms 1910a and 1910b for operative connection to a fluid injector system. The retaining arms 1910a and 1910b can also pivot toward each other to move to a closed position. In the closed position, the retaining arms 1910a and 1910b are positioned in contact with or adjacent to each other, such that the mounted pressure sheath 1906 and syringe 1908 are held within the pressure sheath and syringe retaining assembly 1900, preventing distal movement of the pressure sheath 1906 and syringe 1908. In the closed position, the retaining arms 1910a and 1910b are separated from each other by a second distance. In various embodiments, the first distance between the retaining arms 1910a and 1910b in the open position is greater than the second distance between the retaining arms 1910a and 1910b in the closed position. In various alternative embodiments, retaining arms 1910a, 1910b may be positioned in an intermediate position such that syringe 1908 can be removed from the pressure sheath and syringe retaining assembly 1900, but pressure sheath 1906 is retained within the pressure sheath and syringe retaining assembly 1900 by retaining arms 1910a, 1910b. Retaining arms 1910a, 1910b may be moved to the intermediate position when the operator wishes to replace syringe 1908 within pressure sheath 1906 without removing pressure sheath 1906 from the pressure sheath and syringe retaining assembly 1900. In various embodiments, when retaining arms 1910a, 1910b are moved to the intermediate position, they are positioned at a third distance from each other, wherein the third distance is less than a first distance when retaining arms 1910a, 1910b are in the open position and greater than a second distance when retaining arms 1910a, 1910b are in the closed position.

[0142] Each retaining arm 1910a, 1910b may further include retaining portions 1916a, 1916b, which include respective retaining surfaces operatively connected to the distal ends of the respective base members 1912a, 1912b and 1912c, 1912d. In some examples or aspects, at least a portion of the retaining portions 1916a, 1916b may be made of plastic or metal (e.g., stainless steel). Each retaining portion 1916a, 1916b may be formed into a semicircle, creating a complete circle around the distal ends of the pressure sheath 1906 and the syringe 1908 when formed together with the opposing retaining elements 1916a, 1916b. Each of the retaining portions 1916a, 1916b may have a curvature along its longitudinal axis, the curvature generally corresponding to the curvature of the distal ends of the syringe 1908 and the pressure sheath 1906. The retaining portions 1916a and 1916b maintain contact to prevent distal movement of the pressure sheath 1906 and syringe 1908 within the pressure sheath and syringe retaining assembly 1900. When fluid pressure from the fluid injector causes the pressure sheath 1906 and syringe 1908 to move distally, the retaining portions 1916a and 1916b generate opposing forces in the proximal direction to prevent distal movement of the pressure sheath 1906 and syringe 1908 relative to the fluid injector.

[0143] In various embodiments, each retaining portion 1916a, 1916b may further include a syringe conical support that positions and retains within the retaining elements 1916a, 1916b. This syringe conical support may be made of a transparent or translucent material (e.g., a polymeric material) to support the distal portion of the syringe 1908 and allow inspection of the distal portion of the syringe 1908, such as visual inspection or inspection using a camera, sensor, or other detector device. For example, inspection of the distal portion of the syringe 1908 may allow detection of air within the syringe 1908 or detection of the type of fluid within the syringe 1908, as described in PCT International Application Publications WO 2017 / 040152 and 2017 / 040154, the disclosure of which is incorporated herein by reference. The retaining elements 1916a, 1916b may surround and reinforce the syringe conical support and provide a stronger abutment surface for the conical distal end of the syringe 1908. The syringe conical support can be conical to correspond to the conical shape of the distal end of the syringe 1908. Although the syringe conical support is shown as conical, its shape can be any shape whose profile matches the shape of the distal end of the syringe 1908.

[0144] Continue to refer to Figure 15B , Figure 16B and Figure 17BA linkage arrangement 1920 for moving retaining arms 1910a, 1910b of an actuating pressure sheath and syringe retaining assembly 1900, according to various embodiments, is shown and described. The linkage arrangement 1920 is configured to move retaining arms 1910a, 1910b between a closed position, an intermediate position, and an open position. In various embodiments, an operator can manually activate the linkage arrangement 1920 by pulling the retaining arms 1910a, 1910b apart or pushing them together. In various embodiments, an electromechanical motor 1922 disposed within or operatively connected to the fluid injector (see [link to documentation]) can be used. Figure 18 The linkage arrangement 1920 is activated by a mechanism that initiates the movement of the retaining arms 1910a, 1910b between the closed, intermediate, and open positions. In various embodiments, the linkage arrangement 1920 is configured to move the retaining arms 1910a, 1910b uniformly between the closed, intermediate, and open positions. For example, in one embodiment, "uniformly" is understood to mean that the retaining arms 1910a, 1910b move outward and inward relative to each other at the same or similar speed or rate to ensure that each retaining arm 1910a, 1910b moves the same or similar distance. Through uniform movement, the linkage arrangement 1920 ensures that when moved to the closed, intermediate, or open position, the retaining arms 1910a, 1910b are positioned at the correct distance from each other.

[0145] In various embodiments, the linkage arrangement 1920 may include a first linkage assembly 1924a and a second linkage assembly 1924b. Linkage assemblies 1924a and 1924b may be disposed on opposite sides of the substrate 1902. In various embodiments, the first linkage assembly 1924a and the second linkage assembly 1924b are identical. Therefore, a description of the first linkage assembly 1924a is provided below, which also corresponds to a description of the second linkage assembly 1924b. The first linkage assembly 1924a may include a first retaining arm link 1926a and a second retaining arm link 1926b. The first retaining arm link 1926a may be connected (at one end) to the proximal end of one of the retaining arms 1910a, and the second retaining arm link 1926b may be connected (at one end) to the proximal end of the other retaining arm 1910b. The retaining arm links 1926a and 1926b can be connected to the retaining arms 1910a and 1910b via mechanical fasteners 1928a and 1928b. Each of the retaining arm links 1926a and 1926b can be operably connected to a corresponding connecting link 1930a and 1930b. Each connecting link 1930a and 1930b can be connected (at one end) to the corresponding end of the retaining arm link 1926a and 1926b. Each connecting link 1930a and 1930b can be connected to the corresponding retaining arm link 1926a and 1926b using connecting pins 1932a and 1932b.

[0146] In various embodiments, connecting links 1930a and 1930b can also be connected to the central link 1934. Connecting links 1930a and 1930b can be connected to the central link 1934 using connecting pins 1936a and 1936b. In various embodiments, the central link 1934 can also be connected to the base link 1938, which is also connected to the substrate 1902. The central link 1934 can be connected to the base link 1938 using a connecting pin 1940.

[0147] refer to Figure 15B , Figure 16B and Figure 17B In the operation of linkage arrangement 1920, in order to move retaining arms 1910a and 1910b from the closed position to the open position, retaining arms 1910a and 1910b can be pulled apart from each other. As retaining arms 1910a and 1910b separate, the proximal ends of retaining arm links 1926a and 1926b move inward toward each other in an inward direction. As the proximal ends of retaining arm links 1926a and 1926b move inward toward each other, connecting links 1930a and 1930b also move inward toward each other. The ends of connecting links 1930a and 1930b connected to the central link 1934 begin to rotate relative to each other in a counterclockwise direction. Based on this movement of linkage arrangement 1920, retaining arms 1910a and 1910b are allowed to rotate outward relative to each other to move to the open position. In a similar manner, the linkage arrangement 1920 can be moved in the opposite way to the above to move the retaining arms 1910a, 1910b from the open position to the closed position or the intermediate position.

[0148] The first linkage assembly 1924a may further include a biasing member 1942 configured to bias the first linkage assembly 1924a and indirectly bias the retaining arms 1910a, 1910b toward the closed position. Thus, when an operator or electromechanical motor 1922 pulls the retaining arms 1910a, 1910b apart, the retaining arms 1910a, 1910b are biased toward closing toward each other, while releasing outward pressure on the retaining arms 1910a, 1910b. In various embodiments, the biasing member 1942 may be a spring. The biasing member 1942 may be connected (at one end) to a central link 1934 and (at the opposite end) to a biasing member link 1944. The biasing member link 1944 is connected at both ends to a base link 1938. One end of the biasing member link 1944 is fixed to the base link 1938, and the opposite end of the biasing member link 1944 is pivotally connected to a groove 1946 defined in the base link 1938. The end of the biasing member link 1944 connected to the groove 1946 allows the corresponding end of the biasing member link 1944 to slide along the groove 1946.

[0149] During the operation of the first link assembly 1924a, the ends of the connecting links 1930a and 1930b connected to the central link 1934 rotate in a first or counterclockwise direction, causing the central link 1934 to rotate in the same first or counterclockwise direction. With this counterclockwise rotation, the end of the central link 1934 connected to the bias member 1942 rotates in the first or counterclockwise direction and begins to stretch or expand the bias member 1942. As the central link 1934 continues to rotate, the bias member 1942 continues to be stretched or expanded. With the stretching or expansion of the bias member 1942, the potential energy stored in the bias member 1942 increases. Therefore, as the outward pressure on the retaining arms 1910a and 1910b decreases, the biasing member 1942 is configured to pull the central link 1934 back to its rest position, such that the biasing member 1942 causes the central link 1934 to rotate in a second or clockwise direction to ensure that the connecting links 1930a and 1930b also rotate in a second or clockwise direction, and pulls the retaining arms 1910a and 1910b back to the closed position.

[0150] To ensure a smooth and consistent transition between the closed, open, and intermediate positions, a groove 1946 defined in the base link 1938 allows the end of the bias member 1942 connected to the groove 1946 to maintain balance between the components of the first link assembly 1924a. As the central link 1934 rotates counterclockwise and pulls the connecting end of the bias member 1942 counterclockwise, the opposite end of the bias member 1942 is configured to slide within the groove 1946 to ensure that the bias member 1942 remains substantially horizontal relative to the first link assembly 1924a. Once the retaining arms 1910a, 1910b have been pulled open, the end of the bias member 1942 connected to the groove 1946 is moved to the bottom of the groove 1946 and holds the bias member 1942 in the extended position, allowing the retaining arms 1910a, 1910b to remain in the open position until an inward force is applied to the retaining arms 1910a, 1910b.

[0151] refer to Figure 15C , 16CIn various embodiments, including 17C, the pressure sheath and syringe retainer assembly 1900 may further include features disposed on retaining portions 1916a, 1916b to assist in retaining the pressure sheath 1906 and syringe 1908 within the fluid injector. In one embodiment, each retaining portion 1916a, 1916b may include an inner protrusion 1948 (also referred to as a syringe retaining surface) extending circumferentially along the inner surface of the retaining portion 1916a, 1916b. The inner protrusion 1948 further reduces the diameter of the retaining portions 1916a, 1916b to engage at least a portion of the distal end of the syringe 1908 loaded into the fluid injector. In one embodiment, the inner protrusion 1948 may be dimensioned to engage and establish contact with a drip flange 1950 at the distal end of the syringe 1908, the drip flange 1950 acting as a circumferential wall surrounding the distal end of the syringe 1908. However, it should also be understood that the structure and dimensions of the inner protrusion 1948 can be designed to contact any portion of the distal end of the syringe 1908. The inner protrusion 1948 may include a surface engaging the distal end of the syringe 1908, the distal end being angled relative to the longitudinal axis of the syringe 1908 to generate an inward thrust on the syringe 1908, thereby retaining the syringe 1908 within the fluid injector. When the syringe 1908 attempts to move distally due to fluid pressure applied by the fluid injector, the inner protrusion 1948 may generate an increased inward pressure on the syringe 1908 to ensure that the syringe 1908 remains within the fluid injector. In one embodiment, the drip flange 1950 may extend at a 45-degree angle relative to the longitudinal axis of the syringe 1908, while the inner protrusion 1948 may extend at the same or similar angle relative to the longitudinal axis of the syringe 1908.

[0152] Continue to refer to Figure 15C , 16C In various embodiments, such as 17C, the retaining portions 1916a, 1916b may further define a retaining recess 1952 (also referred to as a pressure sheath retaining surface), configured to receive at least a portion of the pressure sheath 1906 and / or the syringe 1908. In one embodiment, the retaining recess 1952 may be structured and sized to receive the distal end of the pressure sheath 1906 to assist in retaining the pressure sheath 1906 within the fluid injector. The retaining recess 1952 also assists in generating an inward radial pressure to retain the retaining arms 1910a, 1910b in the closed position as the pressure sheath 1906 and syringe 1908 are pushed distally due to the fluid pressure applied by the fluid injector.

[0153] like Figure 19As shown, in various embodiments, the retaining arms 1910a, 1910b may further include at least one finger 1954a, 1954b to assist in opening the retaining arms 1910a, 1910b to insert or remove the pressure sheath 1906 and / or the syringe 1908. In one embodiment, the finger 1954a, 1954b is disposed on each of the base members 1912a, 1912b, 1912c, 1912d. In this embodiment, an operator can apply an outward force on the inner surface of the finger 1954a, 1954b using his / her thumb and forefinger to push the retaining arms 1910a, 1910b apart from each other. In a similar manner, an operator can generate an inward pressing force on the finger 1954a, 1954b to push the retaining arms 1910a, 1910b into the closed position. In another embodiment, individual fingers 1954a and 1954b may be disposed on only one of the retaining arms 1910a and 1910b, and the individual fingers 1954a and 1954b may be used to move the retaining arms 1910a and 1910b between an open position, a closed position, and an intermediate position. In one embodiment, fingers 1954a and 1954b may be positioned at or near the distal end of the retaining arms 1910a and 1910b.

[0154] Figures 20A-22C The structure and operation of a preload pressure sheath and syringe retainer assembly 2000 in another embodiment are shown. Figures 20A-22C A pre-loaded pressure sheath and syringe retainer assembly 2000 is shown after the syringe has been inserted through the distal access opening. The pressure sheath and syringe retainer assembly 2000 includes a... Figures 15A-17C The pressure sheath and syringe retainer assembly 1900 shown have the same base plate and retainer arm.

[0155] Figure 20C , 21C Figures 22C and 22C illustrate further features of the pressure sheath and syringe retaining assembly 2000, including a spring plate 2002 and a key shaft biased in the distal direction when the syringe 2004 is not fully inserted. The spring plate 2002 and the key shaft are connected by a spring plate and a keyway on the key shaft. As the syringe 2004 moves proximally, it presses down the spring-loaded spring plate 2002 at the base of the retaining arms 2006a, 2006b in the proximal direction, thereby seating the syringe 2004 in the pressure sheath 2008. The spring plate 2002 is located in the assembly 2000, with the key shaft 2010 passing through an elongated hole in the spring plate 2002, which allows the plate 2002 to translate in a direction perpendicular to the axis of the key shaft 2010 as the syringe 2004 presses down on the spring plate 2002. The spring plate 2002 may also have a tab that can be aligned with the keyway to prevent rotation of the shaft 2010. The key shaft 2010 can be twisted by spring loading.

[0156] For reference Figure 20C , 21C And 22C, when syringe 2004 is fully inserted, spring plate 2002 releases key shaft 2010, which was previously energized during the removal of the last syringe, as described below. Key shaft 2010 then rotates two similar cam plates 2012 (one on each side of assembly 2000). Figure 20B , 21B (Only one is shown in 22B). The cam plate 2012 then releases the two locking plates 2014 (keeping one on each side of the assembly 2000). Figure 20B , 21B (Only one is shown in 22B), the locking plate 2014 is rotated by spring force and wedged between the retaining arms 2006a, 2006b to prevent them from opening in the closed position.

[0157] like Figures 21A-21C As shown, once the syringe 2004 is fully inserted and the spring plate 2002 has released the key shaft 2010, which was previously energized when the last syringe was removed, and the locking plate 2014 is positioned between the retaining arms 2006a and 2006b, the syringe 2004 is fully installed and locked, as... Figures 20A-20C As shown. Then, the injection process can continue for the fluid injector.

[0158] Removal of syringe 2004 as follows Figures 22A-22C As shown. (Refer to...) Figures 22A-22C To remove syringe 2004, handle 2016 is pulled from its resting locked position to approximately 45 degrees. The two actions occur essentially simultaneously as handle 2016 moves. Handle 2016 is rigidly attached to two gear plates 2018 (one on each side). Figures 22A-22C (Only one is shown in the image), the two gear plates 2018 also have pins 2020 pressed into them at a distance from the axis of rotation. Pins 2020 contact and drive the cam plate 2012 (see image). Figure 22C The cam plate 2012 and the gear plate 2018 share the same axis of rotation. The cam plate 2012 has a cam profile that drives the locking plate 2014 away from the retaining arms 2006a, 2006b, releasing them to allow the syringe to be removed.

[0159] For reference Figures 20A-22C The teeth of gear plate 2018 mesh with the teeth of lever plate 2022, and lever plate 2022 has a fixed axis of rotation on the distal side of the aforementioned plate. As gear plate 2018 rotates (see...), Figure 20B , 21B(and 22B), due to the reduced gear ratio, it drives lever plate 2022 with mechanical advantage. As lever plate 2022 is rotated, the two cam profiles 2024 (one on each side of the assembly) push the proximal portions of retaining arms 2006a, 2006b together, which causes retaining arms 2006a, 2006b to pivot about their axis of rotation, causing them to open and release syringe 2004.

[0160] refer to Figures 22A-22C Once the handle 2016 is moved back to the set position, the key shaft 2010 aligns with the plate on the spring-loaded plate 2002, and the spring plate 2002 is biased in the distal direction, ejecting the syringe 2004 from the distal loading surface for removal by the operator. The assembly 2000 is then ready to install a new syringe for the next process.

[0161] While various examples of this disclosure have been provided in the foregoing description, modifications and alterations can be made to these examples by those skilled in the art without departing from the scope and spirit of this disclosure. Therefore, the foregoing description is intended to be illustrative rather than limiting. The disclosure described above is defined by the appended claims, and all changes to the disclosure falling within the meaning and equivalents of the claims are to be included within their scope.

Claims

1. An assembly for retaining a pressure sheath and a syringe on a fluid injector, the assembly comprising: The substrate, including the main body; At least a first retaining arm and a second retaining arm, said at least a first retaining arm and a second retaining arm operably mounted on the body of said substrate, said first retaining arm having two first support arms pivotally connected to said substrate at a first pivot point, and said second retaining arm having two second support arms pivotally connected to said substrate at a second pivot point, said first retaining arm having a first retaining surface at the distal end of said two first support arms, and said second retaining arm having a second retaining surface at the distal end of said two second support arms, wherein said first retaining surface and second retaining surface are configured to abut a distal surface of at least one of said pressure sheath and said syringe; as well as A linkage assembly operably connected to the proximal ends of the first retaining arm and the second retaining arm. The linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position.

2. The assembly of claim 1, wherein the linkage assembly operably connects the first retaining arm to the second retaining arm such that the first retaining arm and the second retaining arm are configured to move coherently between at least the first open position and the closed position.

3. The assembly of claim 2, wherein the linkage assembly includes at least one biasing member configured to bias the first retaining arm and the second retaining arm to move uniformly between at least the first open position and the closed position.

4. The component according to any one of claims 1 to 3, wherein the first retaining arm and the second retaining arm pivot about the first pivot point and the second pivot point respectively between at least the first open position and the closed position.

5. The component according to any one of claims 1 to 4, wherein the first retaining arm and the second retaining arm are further configured to move to a second open position between the first open position and the closed position.

6. The component according to claim 5, wherein, In the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance being configured to allow insertion and engagement of at least one of the pressure sheath and the syringe with the fluid injector, or to allow removal of at least one of the pressure sheath and the syringe from the fluid injector, wherein the first distance is greater than the outer diameter of the pressure sheath. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance to hold the pressure sheath and the syringe between the first retaining arm and the second retaining arm, wherein the minimum of the second distance is less than the outer diameter of the syringe. In the second open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a third distance to retain the pressure sheath in the fluid injector and allow the syringe to be removed from the fluid injector. Where the first distance is greater than the second distance, and The third distance is less than the first distance and greater than the second distance.

7. The component according to any one of claims 1 to 5, wherein, In the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance being configured to allow insertion and engagement of at least one of the pressure sheath and the syringe with the fluid injector, or to allow removal of at least one of the pressure sheath and the syringe from the fluid injector, wherein the first distance is greater than the outer diameter of the pressure sheath. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance to hold the pressure sheath and the syringe between the first retaining arm and the second retaining arm, wherein the minimum distance of the second distance is less than the outer diameter of the syringe, and The first distance is greater than the second distance.

8. The component according to any one of claims 1 to 7, wherein each of the first retaining arm and the second retaining arm comprises at least one base member operatively connected to the body of the substrate and at least one retaining portion disposed on the distal end of the at least one base member.

9. The component according to any one of claims 1 to 8, wherein the first retaining surface of the first retaining arm comprises a first syringe retaining surface and a first pressure sheath retaining surface, and The second retaining surface of the second retaining arm includes a second syringe retaining surface and a second pressure sheath retaining surface.

10. The component of claim 3, wherein the at least one biasing member is configured to bias the first retaining arm and the second retaining arm in at least one of the first open position, the second open position and the closed position, wherein the second open position is between the first open position and the closed position.

11. An assembly for retaining a pressure sheath and a syringe in a fluid injector, the assembly comprising: The substrate, including the main body; and At least a first retaining arm and a second retaining arm, operably mounted on the body of the substrate, the first retaining arm having two first support arms pivotally connected to the substrate at a first pivot point, and the second retaining arm having two second support arms pivotally connected to the substrate at a second pivot point, the first retaining arm having a first retaining surface at the distal end of the two first support arms, and the second retaining arm having a second retaining surface at the distal end of the two second support arms, wherein the first retaining surface and the second retaining surface are configured to abut a distal surface of at least one of the pressure sheath and the syringe. The two first support arms are pivotally connected to the substrate at a first pivot point, and the two second support arms are pivotally connected to the substrate at a second pivot point.

12. The assembly of claim 11, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each include at least one inner protrusion to engage the distal end of at least one of the pressure sheath and the syringe.

13. The component of claim 12, wherein, At least one of the at least one inner protrusion is a syringe retaining protrusion that extends at an angle relative to the longitudinal axis of the syringe and is configured to interact with a corresponding angled distal surface of the circumferential wall on the distal end of the syringe to push the distal ends of the first retaining arm and the second retaining arm with an inward retaining force.

14. The component according to any one of claims 11 to 13, wherein, At least one of the first retaining arm and the second retaining arm includes at least one finger, the at least one finger being configured to assist in moving the first retaining arm and the second retaining arm between a closed position and an open position.

15. The component of any one of claims 11 to 13, wherein each of the first retaining arm and the second retaining arm includes at least one finger to assist in moving the first retaining arm and the second retaining arm between a closed position and an open position.

16. The assembly according to any one of claims 11 to 15, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each define a retaining groove to receive at least a portion of the distal end of the pressure sheath.

17. The component according to claim 14 or 15, wherein, In the open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance being configured to allow at least one of the pressure sheath and the syringe to be inserted into and engaged with the fluid injector or to allow at least one of the pressure sheath and the syringe to be removed from the fluid injector, wherein the first distance is greater than the outer diameter of the pressure sheath. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance, the second distance being configured to hold the pressure sheath and the syringe between the first retaining arm and the second retaining arm, wherein the minimum distance of the second distance is less than the outer diameter of the syringe, and The first distance is greater than the second distance.

18. The assembly according to any one of claims 11 to 17, wherein the retaining portions of the first retaining arm and the second retaining arm have curvature about the longitudinal axis of the syringe, the curvature corresponding to the curvature of the distal end of at least one of the pressure sheath and the syringe.

19. An assembly for retaining a pressure sheath and a syringe on a fluid injector, the assembly comprising: The substrate, including the main body; At least a first retaining arm and a second retaining arm, the at least first retaining arm and the second retaining arm being operably mounted on the body of the substrate, the first retaining arm having a first retaining surface at its distal end, and the second retaining arm having a second retaining surface at its distal end, wherein the first retaining surface and the second retaining surface are configured to abut against the distal surface of at least one of the pressure sheath and the syringe; and A linkage assembly operably connected to the proximal ends of the first retaining arm and the second retaining arm. The linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position, and Each of the first retaining arm and the second retaining arm includes two first support arms and two second support arms operably connected to the body of the substrate, and the first retaining surface and the second retaining surface are configured to engage at least one of the pressure sheath and the syringe when in the closed position, wherein the first retaining surface of the first retaining arm is disposed on the retaining portion of the first retaining arm, and the second retaining surface of the second retaining arm is disposed on the retaining portion of the second retaining arm.

20. The assembly of claim 19, wherein the linkage assembly operably connects the first retaining arm to the second retaining arm such that the first retaining arm and the second retaining arm are configured to move coherently between at least the first open position and the closed position.

21. The assembly of claim 20, wherein the linkage assembly includes at least one biasing member configured to bias the first retaining arm and the second retaining arm to move uniformly between at least the first open position and the closed position.

22. The assembly according to any one of claims 19 to 21, wherein the proximal ends of the two first support arms of the first retaining arm and the proximal ends of the two second support arms of the second retaining arm are connected to the body of the substrate at a first pivot point and a second pivot point, respectively, such that the first retaining arm and the second retaining arm pivot about the first pivot point and the second pivot point between at least the first open position and the closed position.

23. The component according to any one of claims 19 to 22, wherein the first retaining arm and the second retaining arm are further configured to move to a second open position between the first open position and the closed position.

24. The component according to any one of claims 19 to 23, wherein, In the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance being configured to allow insertion and engagement of at least one of the pressure sheath and the syringe with the fluid injector, or to allow removal of at least one of the pressure sheath and the syringe from the fluid injector, wherein the first distance is greater than the outer diameter of the pressure sheath. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance, the second distance being configured to hold the pressure sheath and the syringe between the first retaining arm and the second retaining arm, wherein the minimum distance of the second distance is less than the outer diameter of the syringe, and The first distance is greater than the second distance.

25. The assembly according to any one of claims 19 to 24, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each include at least one inner protrusion to engage the distal end of at least one of the pressure sheath and the syringe.

26. The assembly of claim 25, wherein the at least one inner protrusion is a syringe retaining protrusion that extends at an angle relative to the longitudinal axis of the syringe and is configured to interact with a corresponding angled distal surface of a circumferential wall on the distal end of the syringe to push the distal ends of the first retaining arm and the second retaining arm with an inward retaining force.

27. The component according to any one of claims 19 to 26, wherein, At least one of the first retaining arm and the second retaining arm includes at least one finger, the at least one finger being configured to assist in moving the first retaining arm and the second retaining arm between the closed position and the first open position.

28. The component of any one of claims 23 to 26, wherein each of the first retaining arm and the second retaining arm includes at least one finger, the at least one finger being configured to assist movement of the first retaining arm and the second retaining arm between the closed position and the first open position and / or the second open position.

29. The assembly according to any one of claims 19 to 28, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each define a retaining groove to receive at least a portion of the distal end of the pressure sheath.

30. The assembly according to any one of claims 19 to 29, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm have curvatures about the longitudinal axis of the syringe, the curvatures corresponding to the curvatures of the distal ends of at least one of the pressure sheath and the syringe.

31. A fluid injector, the fluid injector comprising: Injector housing; At least one port, defined in an injector housing, for receiving at least one syringe, wherein the syringe is received within at least one pressure sheath; as well as A component for retaining the at least one pressure sheath on the fluid injector and retaining the at least one syringe in the at least one port, the component comprising: The substrate, including the main body; At least a first retaining arm and a second retaining arm, said at least a first retaining arm and a second retaining arm, said at least a first retaining arm and a second retaining arm, said at least a first retaining arm and a second retaining arm, said at a second retaining arm, said first retaining arm having a first retaining surface at the distal end of said two first retaining arms, and said second retaining arm having a second retaining surface at the distal end of said two second retaining arms, said first retaining surface and second retaining surface being configured to abut a distal surface of at least one of said pressure sheath and said syringe; and A linkage assembly operably connected to the proximal ends of the first retaining arm and the second retaining arm. The linkage assembly is configured to move at least one of the first retaining arm and the second retaining arm between at least a first open position and a closed position, and Each of the first retaining arm and the second retaining arm includes at least one base member operably connected to the body of the substrate and at least one retaining portion, the at least one retaining portion being disposed at the distal end of the at least one base member to engage at least one of the pressure sheath and the syringe when in the closed position.

32. The fluid injector of claim 31, wherein the linkage assembly operably connects the first retaining arm to the second retaining arm such that the first retaining arm and the second retaining arm are configured to move coherently between at least the first open position and the closed position.

33. The fluid injector of claim 32, wherein the linkage assembly includes at least one biasing member configured to bias the first retaining arm and the second retaining arm to move uniformly between at least the first open position and the closed position.

34. The fluid injector according to any one of claims 31 to 33, wherein the proximal ends of the first retaining arm and the second retaining arm are connected to the body of the substrate at a first pivot point and a second pivot point, respectively, such that the first retaining arm and the second retaining arm pivot about the first pivot point and the second pivot point between at least the first open position and the closed position.

35. The fluid injector according to any one of claims 31 to 34, wherein the first retaining arm and the second retaining arm are further configured to move to a second open position between the first open position and the closed position.

36. The fluid injector according to any one of claims 31 to 35, wherein, In the first open position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a first distance, the first distance being configured to allow at least one of the pressure sheath and the syringe to be inserted into and engaged with the fluid injector or to allow at least one of the pressure sheath and the syringe to be removed from the fluid injector, wherein the first distance is greater than the outer diameter of the pressure sheath. In the closed position, the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are separated from each other by a second distance, the second distance being configured to hold the pressure sheath and the syringe between the first retaining arm and the second retaining arm, wherein the minimum distance of the second distance is less than the outer diameter of the syringe, and The first distance is greater than the second distance.

37. The fluid injector according to any one of claims 31 to 36, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm each include at least one inner protrusion to engage the distal end of at least one of the pressure sheath and the syringe.

38. The fluid injector of claim 37, wherein the at least one inner protrusion is a syringe retaining protrusion that extends at an angle relative to the longitudinal axis of the syringe and is configured to interact with a corresponding angled distal surface of a circumferential wall on the distal end of the syringe to push the distal ends of the first retaining arm and the second retaining arm with an inward retaining force.

39. The fluid injector according to any one of claims 31 to 38, wherein, At least one of the first retaining arm and the second retaining arm includes at least one finger, the at least one finger being configured to assist in moving the first retaining arm and the second retaining arm between the closed position and the first open position.

40. The fluid injector according to any one of claims 35 to 38, wherein each of the first retaining arm and the second retaining arm includes at least one finger, the at least one finger being configured to assist in moving the first retaining arm and the second retaining arm between the closed position and the first open position and / or the second open position.

41. The fluid injector according to any one of claims 31 to 40, wherein a first retaining surface of the first retaining arm and a second retaining surface of the second retaining arm each define a retaining groove to receive at least a portion of the distal end of the pressure sheath.

42. The fluid injector according to any one of claims 31 to 41, wherein the first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm have curvatures about the longitudinal axis of the syringe, the curvatures corresponding to the curvatures of the distal ends of at least one of the pressure sheath and the syringe.

43. The fluid injector according to any one of claims 35 to 42, further comprising an electromechanical motor disposed in the injector housing for moving the first retaining arm and the second retaining arm between the first open position, the second open position and the closed position.

44. The fluid injector according to any one of claims 31 to 43, wherein the syringe includes a drip flange disposed at the distal end of the syringe, and The first retaining surface of the first retaining arm and the second retaining surface of the second retaining arm are configured to engage the drip flange of the syringe to retain the syringe in at least one port of the injector housing.

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