Rotary IVC system

Abstract

The present invention discloses a rotary IVC system, comprising a cage box fixing frame and a cage box. Independent and nested air supply ducts and exhaust ducts are formed in the cage box fixing frame, and a plurality of air supply ports connected to the air supply duct and a plurality of exhaust ducts connected to the exhaust duct are provided on the cage box fixing frame; a plurality of cage boxes are provided on the cage box fixing frame, and each cage box is connected to an air supply port and an exhaust duct. The air supply duct and the exhaust duct can be respectively connected to the fresh air supply and exhaust system in the barrier environment, so that the air in the cage box is continuously discharged to the fresh air supply and exhaust system through the exhaust duct through the exhaust duct, and at the same time, the clean air purified by the fresh air supply and exhaust system is injected into the cage box through the air supply port after passing through the air supply duct, so that the air in the cage box remains fresh and clean. The rotary IVC system of the present invention can greatly reduce the impact of the external environment on the environment inside the cage box and improve the experimental accuracy.

Description

Technical Field

[0001] The present invention relates to a feeding device for experimental animals, in particular to a rotary IVC system. Background Art

[0002] According to the national standard GB14925 "Laboratory Animal Environment and Facilities," the entire process of animal husbandry and experimental environment must meet SPF standards. All experimental units have renovated their experimental environments and built barrier environments, but how to keep barrier environment facilities running and maintain them has become a difficult problem, and very few units can maintain this. In the 1990s, some developed countries began to promote the use of IVCs (Individually Ventilated Cages), which greatly simplified the operating procedures of barrier environments, separated the living environments of humans and animals, and allowed animals to enjoy SPF-level cleanliness in clean cages of 10,000 or above and clean benches of 100 levels. This also eliminated the need for animal keepers and animal experimenters to maintain high levels of cleanliness, effectively prevented cross-infection between animals and between humans, and ensured the health and safety of experimental staff and keepers.

[0003] The application of IVC system cages has changed the original need to maintain a huge overall barrier environment to only maintaining the normal operation of the cages, and the cost required is only 1 / 7 of the cost of maintaining the overall barrier environment. However, the heat, noise, vibration, etc. generated during operation will have a certain impact on the experimental animals. In addition, the cages still occupy a relatively large area, the stocking density is still not high enough, and the cost is still relatively high.

[0004] In light of this, the applicant has proposed a central exhaust ventilation cage system (EVC). This system significantly reduces the floor space required for cages, increases stocking density, and reduces animal husbandry costs without affecting the number of cages that can be placed. However, this central exhaust ventilation cage system (EVC) only exhausts the polluted air inside the cages. The air that enters the cages is still the natural air in the laboratory, which often carries various environmental factors. This prevents animal experiments or animal husbandry from being conducted in a pure environment, which can affect experimental effects and results, making them inaccurate.

[0005] The information disclosed in this background technology section is only intended to enhance understanding of the overall background of the invention and should not be regarded as an admission or any form of suggestion that the information constitutes the prior art already known to a person skilled in the art. Summary of the Invention

[0006] The object of the present invention is to provide a rotary IVC system (EVC) with a simple structure, a small footprint and a high stocking density, which can greatly reduce the impact of the external environment on the environment inside the cage and improve the experimental accuracy.

[0007] To achieve the above objectives, an embodiment of the present invention provides a rotary IVC system, comprising a cage fixing frame and a cage.

[0008] The cage box fixing frame is provided with independent and nested air supply ducts and exhaust ducts, and the cage box fixing frame is provided with multiple air supply ports connected to the air supply ducts and multiple exhaust ducts connected to the exhaust ducts; multiple cage boxes are arranged on the cage box fixing frame, and each cage box is connected to one air supply port and one exhaust duct.

[0009] Among them, the supply air duct and the exhaust air duct can be respectively connected to the fresh air supply and exhaust system in the barrier environment. While keeping the fresh air supply and exhaust system in continuous operation, the air in the cage box is continuously discharged to the fresh air supply and exhaust system through the exhaust duct. At the same time, the clean air purified by the fresh air supply and exhaust system is injected into the cage box through the air supply port after passing through the supply air duct, so that the air in the cage box remains fresh and clean.

[0010] In one or more embodiments of the present invention, the cage box fixing frame includes a plurality of cage box fixing frame units, each of the cage box fixing frame units includes: a fixing frame bottom surface, used to place the cage box; a fixing frame side wall, formed in the middle of the fixing frame bottom surface and vertically passing through the fixing frame bottom surface, the fixing frame side wall is arranged to form an air cavity, and the air supply port is opened on the fixing frame side wall.

[0011] Wherein, a plurality of the cage box fixing frame units are stacked in a vertical direction, and the adjacent fixing frame side walls are sealed and sleeved to form an air supply duct connecting the cage box fixing frame units.

[0012] In one or more embodiments of the present invention, an independent air chamber is also formed in the air cavity formed by the side wall of the fixing frame, and the air chamber is connected to the side wall of the fixing frame through the exhaust duct. Each of the air chambers is sealed and connected to the adjacent air chambers to form an exhaust duct connecting each cage box fixing frame unit.

[0013] In one or more embodiments of the present invention, the rotary IVC system further includes a support tube, which passes through the plurality of air chambers and is sealed between the air chambers. A plurality of exhaust holes are provided on the support tube corresponding to each of the air chambers, and the support tube cooperates with the air chambers to form the exhaust duct.

[0014] In one or more embodiments of the present invention, the total area of ​​the exhaust holes corresponding to each of the air chambers gradually decreases by 8% to 15% along the exhaust direction of the support tube. Preferably, the gradually decreasing ratio is 10%.

[0015] For example, in the exhaust direction of the support tube, the total area of ​​the exhaust holes corresponding to the previous air chamber is π*1 2 cm 2 , then the total area of ​​the exhaust holes corresponding to the latter air chamber is 0.9*π*1 2 cm 2 , and so on.

[0016] In one or more embodiments of the present invention, the number of the exhaust holes on the support tube gradually decreases along the exhaust direction of the support tube.

[0017] In one or more embodiments of the present invention, the size of the exhaust holes on the support tube gradually decreases along the exhaust direction of the support tube.

[0018] In one or more embodiments of the present invention, reinforcing ribs are further provided between the air chamber and the side wall of the fixing frame, and the reinforcing ribs include a tube portion provided on the lower end surface of the air chamber and surrounding the support tube, and a plurality of rib portions extending from the tube portion toward the side wall of the fixing frame.

[0019] In one or more embodiments of the present invention, a sealing end cover is provided on the air chamber, and a through hole is formed on the sealing end cover for the support tube to pass through. The sealing end cover seals the air chamber so that it is fluidically connected only with the interior of the support tube and the exhaust pipe.

[0020] In one or more embodiments of the present invention, the upper end surface of the bottom surface of the fixing frame is divided into a plurality of equal parts corresponding to a plurality of cage boxes by a plurality of radially arranged ridges, wherein each equal part is provided with a slide groove extending from the edge of the bottom surface of the fixing frame to the center thereof and two fixing holes, and the slide groove and the two fixing holes are distributed in a triangular shape; the lower end of the cage box is provided with a slide rail and a fixing part that cooperate with the slide groove and the fixing hole.

[0021] In one or more embodiments of the present invention, the side wall of the fixing frame includes a first polygonal side wall formed on the upper end surface of the bottom surface of the fixing frame and a second polygonal side wall formed on the lower end surface of the bottom surface of the fixing frame, the first polygonal side wall and the second polygonal side wall are coaxially arranged, and each side of the first polygonal side wall cooperates with two adjacent convex strips.

[0022] In one or more embodiments of the present invention, the lower end of the second polygonal side wall of the bottom surface of the fixing frame can be sealed and fitted with the upper end of the first polygonal side wall of the bottom surface of another fixing frame arranged below the bottom surface of the fixing frame to form an air supply duct connecting each cage box fixing frame unit.

[0023] In one or more embodiments of the present invention, the rotary IVC system further comprises a cage frame for accommodating a cage fixing frame, the cage frame comprising a bottom plate, a top plate and a plurality of frame liners arranged between the top plate and the bottom plate, the cage fixing frame can be rotatably arranged in the cage frame, and a plurality of casters are fixedly arranged on the lower end surface of the bottom plate.

[0024] In one or more embodiments of the present invention, exhaust ports connected to the exhaust duct are provided on the top plate and the bottom plate, and air inlets connected to the air supply duct are provided around the exhaust ports on the top plate and the bottom plate. The exhaust ports and the air inlets are connected to the fresh air supply and exhaust system in the barrier environment via a cage box frame fluid duct with a quick plug-in connector, thereby forming a cage box circulating fresh air supply and exhaust system.

[0025] In one or more embodiments of the present invention, sealing rings and rotating shafts are provided between the lower end surface of the top plate and the upper end surface of the cage box fixing frame at the joint position corresponding to the air supply duct and the air inlet, and the joint position corresponding to the exhaust duct and the air exhaust port, and a rotating shaft is provided on the bottom plate at the joint position corresponding to the exhaust duct and the air exhaust port.

[0026] In one or more embodiments of the present invention, the lengths and apertures of the plurality of exhaust pipes are the same, and the apertures of the plurality of air supply ports are the same.

[0027] Compared with the existing technology, the rotary IVC system of the embodiment of the present invention has a simple structure, small footprint and high stocking density. It forms two non-interfering ventilation pipes in the cage box fixing frame, connects the cage box to the two ventilation pipes respectively, and connects the two ventilation pipes to the fresh air supply and exhaust system in the barrier environment, so that the fresh air supply and exhaust system, the cage box fixing frame and the cage box form an internal circulation, and the dirty air in the cage box is extracted and purified and then sent back to the cage box, which can greatly reduce the impact of the external environment on the environment inside the cage box and improve the experimental accuracy.

[0028] The rotary IVC system of the present invention strengthens the cage frame structure by providing a support tube. An exhaust duct (for exhaust air) is constructed by connecting independent air chambers within the cage frame unit to the support tube. By varying the total area of ​​the exhaust holes corresponding to each air chamber, gradually reducing it by 8% to 15% along the exhaust direction of the support tube, the air volume extracted by the support tube is made substantially uniform, thereby ensuring a consistent flow rate of polluted air extracted from the cage, further controlling interference from experimental factors. Specifically, by gradually decreasing the number of exhaust holes or the inner diameter of the exhaust holes along the exhaust direction, the air volume extracted by the support tube is substantially uniform, ensuring a consistent flow rate of fresh air entering the cage, further controlling interference from experimental factors. Furthermore, the independent air chambers within the cage frame unit can temporarily store and buffer polluted air extracted through the support tube, further improving the accuracy of the polluted air volume extracted from each cage.

[0029] The rotary IVC system of the embodiment of the present invention increases the number of animals raised per unit area, making more scientific and efficient use of space, and reducing costs by another 2 / 3 compared to existing IVC systems. This enables many experimental units that are forced to lower their experimental environment standards and requirements due to unaffordable maintenance costs to conduct experimental operations within the experimental standards mandated by the state, thereby greatly improving the accuracy and reliability of experimental data. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 is a three-dimensional structural diagram of a rotary IVC system according to one embodiment of the present invention;

[0031] Figure 2 is a cross-sectional view of a rotary IVC system according to one embodiment of the present invention;

[0032] Figure 3 yes Figure 2 A magnified view of the details of part A;

[0033] Figure 4 1. It is a three-dimensional structural diagram of a cage fixing frame unit in a rotary IVC system according to one embodiment of the present invention;

[0034] Figure 5 1 is a top view of a cage fixing frame unit in a rotary IVC system according to an embodiment of the present invention;

[0035] Figure 6 1 is a side view of a cage fixing frame unit in a rotary IVC system according to an embodiment of the present invention;

[0036] Figure 7 is a cross-sectional view of a cage fixing frame unit in a rotary IVC system according to one embodiment of the present invention;

[0037] Figure 8 1 is a structural diagram of a cage box in a rotary IVC system according to an embodiment of the present invention. DETAILED DESCRIPTION

[0038] The specific embodiments of the present invention are described in detail below with reference to the accompanying drawings, but it should be understood that the protection scope of the present invention is not limited by the specific embodiments.

[0039] Unless expressly stated otherwise, throughout the specification and claims, the term "comprise" or variations such as "include" or "comprising", etc., will be understood to include the stated elements or components but not to exclude other elements or other components.

[0040] like Figures 1 to 2 As shown, one embodiment of the present invention provides a rotary IVC system, comprising a cage frame 10, a cage mounting bracket 20, a support tube 30, and cages 40. The cage mounting bracket 20 is disposed within the cage frame 10; the support tube 30 extends longitudinally through the cage frame 10 and the cage mounting bracket 20; and a plurality of cages 40 are disposed on the cage mounting bracket 20. The cage mounting bracket 20 comprises a plurality of stacked circular rotating cage mounting bracket units 21, each of which accommodates a plurality of cages 40.

[0041] The cage frame 10 can be made of 304 stainless steel. The cage frame 10 includes a bottom plate 11, a top plate 12, and four frame liners 13. The four frame liners 13 are distributed at the four corners of the cage frame 10, and their ends are fixedly connected to the bottom plate 11 and the top plate 12 respectively. The bottom plate 11 and the top plate 12 are provided with symmetrically arranged air exhaust ports 15, and the top plate 12 is provided with air inlets 16 around the air exhaust ports 15. The air exhaust ports 15 and the air inlets 16 are respectively connected to the fresh air supply and exhaust system of the barrier environment through the cage frame fluid ducts with quick plug connectors, thereby forming a cage circulating fresh air supply and exhaust system. Four casters 14 are fixedly connected to the four corners of the lower end surface of the bottom plate 11.

[0042] like Figures 4 to 7As shown, the circular rotating cage mounting unit 21 includes a mounting bottom surface 211, which is circular in this embodiment. The upper end surface of the mounting bottom surface 211 is divided into ten equal sections by twenty radially arranged protrusions 212. Each section is provided with a chute 213 extending from the edge of the mounting bottom surface toward its center. The width of the chute 213 gradually decreases as it approaches the center of the mounting bottom surface 211. Two fixing holes 214 are further provided on the bottom surface 211 of the fixing frame in each equal part on both sides of the slide groove 213, and a through hole 215 is also provided at the narrower end of the slide groove 213. A slide rail that cooperates with the slide groove 213 and a fixing portion 44 that cooperates with the fixing hole 214 are provided on the lower end surface of each cage box 40. A snap-fit ​​portion 43 is provided at the front end of the slide rail. By the cooperation between the slide rail and the slide groove 213, the cooperation between the fixing portion 44 and the fixing hole 214, and the cooperation between the snap-fit ​​portion 43 and the through hole 215, a stable triangular fixed structure can be formed between the cage box 40 and the bottom surface 211 of the fixing frame to prevent the cage box 40 from tilting or loosening. Figure 8 In other embodiments, the slide rail may not be provided, and the engaging portion 43 may be directly constructed into a strip-shaped track structure, which may also serve as a slide rail.

[0043] A first polygonal side wall 216 in the shape of a decagon and a second polygonal side wall 217 in the shape of a decagon are coaxially provided at the center of the upper and lower end surfaces of the bottom surface 211 of the fixing frame, respectively. The first polygonal side wall 216 and the second polygonal side wall 217 are coaxially arranged and vertically pass through the bottom surface 211 of the fixing frame. The first polygonal side wall 216 and the second polygonal side wall 217 together form the fixing frame side wall of the cage box fixing frame unit 21. The fixing frame side wall is surrounded to form an air cavity 218. When a plurality of cage box fixing frame units 21 are stacked in the vertical direction, the adjacent fixing frame side walls are sealed together (the lower end of the second polygonal side wall 217 of the fixing frame bottom surface 211 located above can be sealed together with the upper end of the first polygonal side wall 216 of another fixing frame bottom surface 211 located below the fixing frame bottom surface 211), so that the plurality of air cavities 218 are nested up and down to form an air supply duct 50 connecting the cage box fixing frame units 21, as shown in FIG. Figure 2 and Figure 3 shown.

[0044] Each side of the first polygonal side wall 216 mates with the two adjacent protrusions 212, and the height of the first polygonal side wall 216 is determined by the height of the corresponding cage 40. The lower end of the second polygonal side wall 217 can be sealed and fitted with the upper end of the first polygonal side wall 216 of the adjacent fixing frame bottom surface 211. This not only allows the adjacent cage fixing frame units 21 to be stacked and fixed in the vertical direction to prevent them from collapsing, but also forms an air supply duct 50 connecting the cage fixing frame units 21. To further enhance the stability of the cage fixing frame 20, the lower end of the second polygonal side wall 217 can be further fixed with screws after being sealed and fitted with the upper end of the first polygonal side wall 216 of the adjacent fixing frame bottom surface 211.

[0045] In other embodiments, the number of the ridges 212 may be changed as needed, and accordingly, the number of sides of the first polygonal side wall 216 and the second polygonal side wall 217 may also be changed to correspond to the ridges 212 .

[0046] Each side of the first polygonal sidewall 216 is provided with an air supply port 2161, which communicates with the air supply duct 50 and is used to cooperate with an external fresh air supply and exhaust system to deliver purified air into the cage 40. The apertures of the multiple air supply ports 2161 are identical. Each side of the first polygonal sidewall 216 is also provided with an exhaust duct 2162, which is used to cooperate with the external fresh air supply and exhaust system to extract contaminated air from the cage 40.

[0047] An independent air chamber 219 is also formed in the air cavity 218 formed by the side wall of the fixing frame, and the air chamber 219 is connected to the side wall of the fixing frame by an exhaust duct 2162. When the cage box fixing frame units 21 are stacked, each air chamber 219 is sealed and connected with the adjacent air chambers 219, forming an exhaust duct 60 connecting each cage box fixing frame unit 21. The exhaust duct 60 is coaxially nested with the air supply duct 50 and is independently arranged. The diameter of the exhaust duct 60 is much smaller than the diameter of the air supply duct 50. Multiple exhaust ducts 2162 connect the exhaust duct 60 and the cage box 40, and the lengths and apertures of the multiple exhaust ducts 2162 are the same, such as Figure 2 and Figure 4 shown.

[0048] like Figure 2 and Figure 3As shown, the support tube 30 passes through multiple air chambers 219 and is sealed between the top plate 12 and the bottom plate 11. It is rotatably arranged between the air chambers 219 and the exhaust ports of the top plate 12 and the bottom plate 11. The support tube 30 is provided with multiple exhaust holes 31 corresponding to each air chamber 219. The support tube 30 and the air chamber 219 cooperate to form an exhaust duct 60. The upper or lower end of the support tube 30 can be connected to the fresh air supply and exhaust system of the barrier environment through the exhaust port 15 via a cage frame fluid duct with a quick plug connector (connected to the exhaust channel of the fresh air supply and exhaust system), thereby extracting the dirty air from the cage 40. The provision of the support tube 30 can strengthen the structure of the cage fixing frame and improve its stability. At the same time, in order to ensure that the flow rate of the dirty air extracted from the cage box 40 is consistent and to further control the interference of experimental influencing factors, the total area of ​​the exhaust holes 31 corresponding to each air chamber 219 gradually decreases at a ratio of 8% to 15% along the exhaust direction of the support tube 30. Preferably, the gradually decreasing ratio is selected to be 10%.

[0049] For example, in a specific embodiment, this can be achieved by gradually reducing the number of exhaust holes 31 on the support tube 30 along the exhaust direction of the support tube 30 and / or gradually reducing the size of the exhaust holes 31 on the support tube 30 along the exhaust direction of the support tube 30.

[0050] For another example, in the exhaust direction of the support tube 30, the total area of ​​the exhaust holes 31 corresponding to the previous air chamber 219 is π*1 2 cm 2 , then the total area of ​​the exhaust holes 31 corresponding to the next air chamber 219 is 0.9*π*1 2 cm 2 , and so on.

[0051] like Figure 3 As shown, the air chamber 219 is composed of an annular inner sidewall 2192, an inner bottom wall 2193, and a sealing end cap 2191. The sealing end cap 2191 and the inner bottom wall 2193 are formed with through-holes for passing the support tube 30 through the through-holes, which are sealed to the support tube 30 by a sealing ring. The exhaust duct 2162 is disposed between the annular inner sidewall 2192 and the sidewall of the fixed frame, and in conjunction with the reinforcing ribs 220, allows the air chamber 219 to be independently and stably located within the air cavity 218. The sealing end cap 2191 cooperates with the sealing ring to seal the air chamber 219, so that it is fluidically connected only to the interior of the support tube 30 and the exhaust duct 2162. When multiple cage box fixed frame units 21 are stacked vertically, the adjacent fixed frame sidewalls are sealed together, and the space between the fixed frame sidewalls, the support tube 30, and the annular inner sidewall 2192 forms the air supply duct 50, while the interior of the support tube 30 and the air chamber 219 form the exhaust duct 60.

[0052] In other embodiments, the air chamber 219 may be formed solely by the annular inner sidewall 2192, and the height relationship between the annular inner sidewall 2192 and the sidewall of the mounting frame satisfies that, when multiple cage-box mounting frame units 21 are stacked vertically and adjacent mounting frame sidewalls are sealed together, adjacent annular inner sidewalls 2192 are also sealed together, and the support tube 30 is disposed within the annular inner sidewall 2192. In this case, the space between the mounting frame sidewall and the annular inner sidewall 2192 forms the air supply duct 50, and the interior of the support tube 30 and the interior of the annular inner sidewall 2192 communicate to form the exhaust duct 60. Alternatively, the support tube 30 may be omitted, and the exhaust duct 60 may be formed directly within the annular inner sidewall 2192. In this case, the diameter of the exhaust duct 2162 in each air chamber 219 follows the same pattern of variation as the exhaust holes 31 in the support tube 30, such that the diameter of the exhaust duct 2162 gradually decreases in the direction of exhaust.

[0053] like Figure 3 and Figure 7 As shown, a reinforcing rib 220 is further provided between the air chamber 219 and the side wall of the fixing frame. The reinforcing rib 220 includes a tube portion 221 provided on the lower end surface of the air chamber 219 and surrounding the support tube 40, and a plurality of rib portions 222 extending from the tube portion 221 toward the side wall of the fixing frame.

[0054] Seals and rotating shafts are installed between the lower end surface of the top plate 12 and the upper end surface of the cage holder 20, corresponding to the junctions between the air supply duct 50 and the air inlet 16, and between the exhaust duct 60 and the air outlet 15. The seals are wear-resistant, high-pressure-resistant, and corrosion-resistant. The rotating shaft allows the cage holder 20 to rotate. The cage holder unit 21 at the bottom is provided with a cover at its bottom that seals the air supply duct 50. In this embodiment, the air supply duct 50 is used for air supply, and the second exhaust duct 60 is used for exhaust.

[0055] like Figure 8 As shown, cage 40 includes a cage body 41 and a cage cover 42, which is sealed to cage body 41. Cage 40 can be made of high-temperature polysulfone or PC plastic, which has excellent resistance to acidic and alkaline detergents or steam sterilization, and even maintains its strength after repeated autoclaving, resulting in a long service life. Furthermore, air vents 411 and 412 are provided at the inner ends of cage 40. These vents are equipped with rubber air ducts 413, which can be inserted into air supply vents 2161 and exhaust ducts 2162 to achieve fluid communication between cage 40 and the air supply and exhaust ducts 50 and 60.

[0056] In addition, the cage box 40 is also provided with a water bottle 414 and a food box for the animals to drink water. Of course, according to the needs of actual application, an automatic drinking water and feeding system can also be provided.

[0057] In the rotary IVC system of the present invention, the air supply duct 50 and the exhaust duct 60 can be respectively connected to the fresh air supply and exhaust system in the barrier environment. While keeping the fresh air supply and exhaust system in continuous operation, the air in the cage box 40 is continuously discharged to the fresh air supply and exhaust system through the exhaust duct 2162 and the exhaust duct 60. At the same time, the clean air purified by the fresh air supply and exhaust system is injected into the cage box 41 through the air supply port 2161 after passing through the air supply duct 50, so that the air in the cage box 41 remains fresh and clean.

[0058] Compared with the existing technology, the rotary IVC system of the embodiment of the present invention has a simple structure, small footprint and high stocking density. It forms two non-interfering ventilation pipes in the cage box fixing frame, connects the cage box to the two ventilation pipes respectively, and connects the two ventilation pipes to the fresh air supply and exhaust system in the barrier environment, so that the fresh air supply and exhaust system, the cage box fixing frame and the cage box form an internal circulation, and the dirty air in the cage box is extracted and purified and then sent back to the cage box, which can greatly reduce the impact of the external environment on the environment inside the cage box and improve the experimental accuracy.

[0059] The rotary IVC system of the present invention strengthens the cage frame structure by providing a support tube. An exhaust duct (for exhaust air) is constructed by connecting independent air chambers within the cage frame unit to the support tube. By varying the total area of ​​the exhaust holes corresponding to each air chamber, gradually reducing it by 8% to 15% along the exhaust direction of the support tube, the air volume extracted by the support tube is made substantially uniform, thereby ensuring a consistent flow rate of polluted air extracted from the cage, further controlling interference from experimental factors. Specifically, by gradually decreasing the number of exhaust holes or the inner diameter of the exhaust holes along the exhaust direction, the air volume extracted by the support tube is substantially uniform, ensuring a consistent flow rate of fresh air entering the cage, further controlling interference from experimental factors. Furthermore, the independent air chambers within the cage frame unit can temporarily store and buffer polluted air extracted through the support tube, further improving the accuracy of the polluted air volume extracted from each cage.

[0060] The rotary IVC system of the embodiment of the present invention increases the number of animals raised per unit area, making more scientific and efficient use of space, and reducing costs by another 2 / 3 compared to existing IVC systems. This enables many experimental units that are forced to lower their experimental environment standards and requirements due to unaffordable maintenance costs to conduct experimental operations within the experimental standards mandated by the state, thereby greatly improving the accuracy and reliability of experimental data.

[0061] The foregoing descriptions of specific exemplary embodiments of the present invention are for purposes of illustration and description. These descriptions are not intended to limit the invention to the precise forms disclosed, and it is apparent that many variations and modifications are possible in light of the foregoing teachings. The exemplary embodiments have been selected and described for the purpose of explaining the specific principles of the invention and their practical application, thereby enabling those skilled in the art to realize and utilize a variety of exemplary embodiments of the invention and various options and modifications. The scope of the invention is intended to be defined by the claims and their equivalents.

Claims

1. A rotary IVC system, characterized in that: include: A cage box fixing frame, wherein an air supply duct and an exhaust duct are formed in the cage box fixing frame and are independently and nested with each other, a plurality of air supply ports communicating with the air supply duct and a plurality of exhaust ducts communicating with the exhaust duct are provided on the cage box fixing frame, the cage box fixing frame comprises a plurality of cage box fixing frame units, each of the cage box fixing frame units comprises a fixing frame side wall, the fixing frame side wall is arranged to form an air cavity, and an independent air chamber is further formed in the air cavity formed by the fixing frame side wall; Cage boxes, a plurality of said cage boxes are arranged on said cage box fixing frame, and each of said cage boxes is connected to one of said air supply ports and one of said exhaust pipes; A support tube, the support tube passing through the plurality of air chambers and being sealed with the air chambers, the support tube being provided with a plurality of exhaust holes corresponding to each of the air chambers, the support tube and the air chambers cooperating to form the exhaust duct, the total area of ​​the exhaust holes corresponding to each of the air chambers gradually decreasing at a ratio of 8% to 15% along the exhaust direction of the support tube; Among them, the air supply duct and the exhaust duct can be respectively connected to the fresh air supply and exhaust system in the barrier environment. While keeping the fresh air supply and exhaust system in continuous operation, the air in the cage box is continuously discharged to the fresh air supply and exhaust system through the exhaust duct, and the clean air purified by the fresh air supply and exhaust system is injected into the cage box through the air supply port after passing through the air supply duct, so that the air in the cage box remains fresh and clean.

2. The rotary IVC system according to claim 1, wherein: Each of the cage fixing frame units comprises: The bottom surface of the fixed frame is used to place the cage box; and The side wall of the fixing frame is formed in the middle of the bottom surface of the fixing frame and vertically penetrates the bottom surface of the fixing frame, and the air supply port is opened on the side wall of the fixing frame; Wherein, a plurality of the cage box fixing frame units are stacked in a vertical direction, and the adjacent fixing frame side walls are sealed and sleeved to form an air supply duct connecting the cage box fixing frame units.

3. The rotary IVC system according to claim 2, wherein: The air chamber is connected to the side wall of the fixing frame through the exhaust pipe, and each air chamber is sealed and connected to the adjacent air chamber to form an exhaust duct connecting each cage box fixing frame unit.

4. The rotary IVC system according to claim 1, wherein: The number of the exhaust holes on the support tube gradually decreases along the exhaust direction of the support tube; and / or, The size of the air exhaust holes on the support tube gradually decreases along the air exhaust direction of the support tube.

5. The rotary IVC system according to claim 1, wherein: A reinforcing rib is further provided between the air chamber and the side wall of the fixing frame. The reinforcing rib includes a tube portion provided on the lower end surface of the air chamber and surrounding the support tube, and a plurality of rib portions extending from the tube portion toward the side wall of the fixing frame.

6. The rotary IVC system according to claim 1, wherein: The air chamber is provided with a sealing end cover, which is formed with a through hole for the support tube to pass through. The sealing end cover seals the air chamber so that it is in fluid communication only with the interior of the support tube and the exhaust pipe.

7. The rotary IVC system according to claim 2, wherein: The upper end surface of the bottom surface of the fixing frame is divided into a plurality of equal parts corresponding to a plurality of cage boxes by a plurality of radially arranged convex strips, wherein each equal part is provided with a slide groove extending from the edge of the bottom surface of the fixing frame to its center part and two fixing holes, and the slide groove and the two fixing holes are distributed in a triangular shape; the lower end of the cage box is provided with a slide rail and a fixing part that cooperate with the slide groove and the fixing hole.

8. The rotary IVC system according to claim 7, wherein: The fixing frame side wall includes a first polygonal side wall formed on the upper end surface of the fixing frame bottom surface and a second polygonal side wall formed on the lower end surface of the fixing frame bottom surface, the first polygonal side wall and the second polygonal side wall are coaxially arranged, and each side of the first polygonal side wall cooperates with two adjacent convex strips; The lower end of the second polygonal side wall of the bottom surface of the fixing frame can be sealed and sleeved with the upper end of the first polygonal side wall of the bottom surface of another fixing frame arranged below the bottom surface of the fixing frame to form an air supply duct connecting each cage box fixing frame unit.

9. The rotary IVC system of claim 1, wherein: The rotary IVC system also includes a cage frame for accommodating a cage fixing frame, the cage frame including a bottom plate, a top plate and a plurality of frame liners arranged between the top plate and the bottom plate, the cage fixing frame can be rotatably arranged in the cage frame, and a plurality of casters are fixedly arranged on the lower end surface of the bottom plate.

10. The rotary IVC system according to claim 9, wherein: The top plate and the bottom plate are provided with exhaust ports connected to the exhaust duct, and the top plate is provided with air inlets connected to the air supply duct around the exhaust ports. The exhaust ports and the air inlets are connected to the fresh air supply and exhaust system in the barrier environment via a cage frame fluid duct with a quick plug-in connector, thereby forming a cage circulating fresh air supply and exhaust system.

11. The rotary IVC system according to claim 10, wherein: Sealing rings and rotating shafts are provided between the lower end surface of the top plate and the upper end surface of the cage box fixing frame at the joint position corresponding to the air supply duct and the air inlet, and the joint position corresponding to the exhaust duct and the air exhaust port. A rotating shaft is provided on the bottom plate at the joint position corresponding to the exhaust duct and the air exhaust port.

12. The rotary IVC system of claim 1, wherein: The lengths and apertures of the plurality of exhaust pipes are the same, and the apertures of the plurality of air supply ports are the same.

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