Dialysate supply device
By employing components such as reverse osmosis water pipelines, feedstock pipelines, mixers, and control devices in the dialysate supply device, disinfection and cleaning of the dialysate supply device without the need for disinfection and cleaning of the pipelines are achieved. This solves the problems of increased costs and drug leakage in existing technologies and enables effective dialysate supply.
Patent Information
- Application Number
- CN202080083623.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2019-12-04
- Filing Date
- 2020-12-04
- Publication Date
- 2026-01-06
- Estimated Expiration
- 2040-12-04
AI Technical Summary
In existing dialysis fluid supply devices, the installation of disinfection and cleaning pipelines increases costs and requires a conductivity testing device to monitor valve leaks, posing a risk of drug leakage into the dialysis fluid.
The system employs reverse osmosis water pipelines, feedstock pipelines, mixers, dialysate supply pipelines, chemical solution pipelines, drain pipelines, a feedstock pump that can rotate in both directions, a check valve, and a control device. The control device rotates the feedstock pump in the forward direction and closes the chemical solution valve and drain valve when generating dialysate, and reverses the feedstock pump and opens the chemical solution valve and drain valve when disinfecting or cleaning, thus achieving disinfection and cleaning of pipelines without the need for disinfection and cleaning.
Effective disinfection and cleaning of the raw solution pipeline can be achieved without the need for disinfection and cleaning pipelines, reducing costs and preventing the drug solution from mixing into the dialysate.
Smart Images
Figure CN114761049B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to a dialysate supply device for supplying the necessary dialysate during dialysis treatment. Background Technology
[0002] Dialysis treatment is performed using a dialysis device, which removes waste and water from the blood by circulating the patient's blood outside the body and allowing dialysate to flow into the hemodialyzer. For example, in dialysis centers and large hospitals, multiple dialysis devices are installed, configured to receive dialysate from a dialysate supply device for dialysis treatment.
[0003] The dialysate supply device comprises a water supply tank for storing purified reverse osmosis water, a raw material tank for storing dialysate, a mixer for mixing the raw material and reverse osmosis water to generate dialysate, a water supply line connecting the water supply tank and the mixer, a raw material line connecting the raw material tank and the mixer, a dialysate tank storing the dialysate generated in the mixer, various pumps, and various valves. Furthermore, the dialysate supply device also includes: a chemical solution line supplying disinfectant and cleaning solutions to the water supply tank or dialysate tank, and a disinfection and cleaning line connecting the water supply tank or dialysate tank to the upstream side of the raw material line and supplying the chemical solution supplied from the chemical solution line to the water supply tank or dialysate tank to the raw material line.
[0004] The disinfection and cleaning pipeline is used for disinfection and cleaning from the upstream side of the raw solution pipeline, and is sealed by a valve mechanism when not in use. However, if a leak occurs due to deterioration of the valve mechanism, there is a risk that the leaked solution from the disinfection and cleaning pipeline may mix with the dialysate through the raw solution pipeline. To solve this problem, Patent Document 1 proposes a solution by installing a conductivity detection mechanism on the raw solution pipeline to monitor for leaks in the valve mechanism.
[0005] Existing technical documents
[0006] Patent documents
[0007] Patent Document 1: Japanese Patent No. 3971659 Summary of the Invention
[0008] The problem that the invention aims to solve
[0009] In the method described in the aforementioned Patent Document 1, a disinfection and cleaning pipeline is required for disinfecting and cleaning the raw liquid pipeline, and a conductivity detection mechanism needs to be installed on the raw liquid pipeline to monitor for leaks, which incurs costs.
[0010] Therefore, the purpose of this invention is to provide a dialysate supply device that can disinfect and clean the raw solution pipeline without the need for disinfection and cleaning pipelines.
[0011] Methods for solving problems
[0012] This invention relates to a dialysate supply device, comprising: a reverse osmosis water pipeline for supplying reverse osmosis water; a feedstock pipeline for supplying dialysate; a mixer connected to the reverse osmosis water pipeline and the feedstock pipeline, for mixing the reverse osmosis water and the dialysate to generate dialysate; a dialysate supply pipeline connected to the mixer for supplying the generated dialysate; a pharmaceutical supply pipeline for supplying pharmaceuticals to the reverse osmosis water pipeline; a drain pipeline connected to the feedstock pipeline; and a feedstock pump capable of forward and reverse rotation, disposed within the feedstock pipeline. A one-way valve is disposed in the feedstock line at a position closer to the feedstock supply side than the connection portion with the drain line; a drain valve is disposed in the drain line; a medication valve is disposed in the medication line; and a control device, wherein, when generating dialysate, the feedstock pump is rotated forward and the medication valve and the drain valve are closed, and when disinfecting or cleaning the dialysate supply device, the feedstock pump is rotated in reverse and the medication valve and the drain valve are opened.
[0013] Furthermore, preferably, the dialysate supply device also includes a water tank for storing reverse osmosis water, which is connected to the upstream side of the reverse osmosis water pipeline, and the drug supply pipeline is connected to the bottom of the water tank, through which the drug is supplied to the dialysate supply pipeline.
[0014] The effects of the invention
[0015] According to the dialysis fluid supply device of the present invention, the original fluid pipeline can be disinfected and cleaned without the need for disinfection and cleaning pipelines. Attached Figure Description
[0016] [ Figure 1 [ ] is a schematic structural diagram of the dialysate supply device according to an embodiment of the present invention, and is a diagram showing the state in which dialysate is being generated.
[0017] [ Figure 2 [ ] is a block diagram of the dialysate supply device.
[0018] [ Figure 3 The schematic structural diagram of the dialysate supply device according to the embodiment is a diagram showing the state of disinfection or cleaning of the dialysate supply device. Detailed Implementation
[0019] Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
[0020] Figure 1 This is a diagram showing the schematic structure of the dialysate supply device 1 according to an embodiment of the present invention.
[0021] The dialysate supply device 1 includes a water supply tank T10, a reverse osmosis water pipeline L1, a chemical solution pipeline L2, raw solution tanks T31 and T32, raw solution pipeline L3, a drain pipeline L4, a mixer 60, a dialysate tank T50, a dialysate supply pipeline L5, and a control device 70.
[0022] Water supply tank T10 stores reverse osmosis water. Water supply tank T10 is positioned, for example, at a predetermined height of approximately 1.5m to 2.0m above ground level. A partition wall 11 is provided inside water supply tank T10. Through this partition wall 11, the interior of water supply tank T10 is divided into a constant water level section T10a for maintaining a constant water level of the reverse osmosis water, and a storage section T10b for receiving reverse osmosis water overflowing from the constant water level section T10a.
[0023] Furthermore, the water supply tank T10 has a delivery pipe L10 for transferring liquid from the storage section T10b to the constant water level section T10a. A water supply pump P10 is installed on the delivery pipe L10. By operating the water supply pump P10, water from the storage section T10b is transferred to the constant water level section T10a, thus maintaining a constant water level in the constant water level section T10a. Additionally, water level sensors LS11 and LS12 are installed in the storage section T10b of the water supply tank T10.
[0024] The reverse osmosis water pipeline L1 receives water from a reverse osmosis water (hereinafter referred to as RO water) supply source and supplies RO water. The reverse osmosis water pipeline L1 includes an upstream reverse osmosis water pipeline L11 that supplies RO water to the water supply tank T10, and downstream reverse osmosis water pipelines L12 and L13 that supply RO water stored in the water supply tank T10 to the downstream side (the mixer 60 side described later).
[0025] The upstream side of the upstream reverse osmosis water pipeline L11 is connected to the RO water supply source, and the downstream side is connected to the bottom of the storage section T10b of the water supply tank T10. A water supply shut-off valve V10 is installed on the upstream reverse osmosis water pipeline L11. In addition, a drain pipeline L111 branches off from the upstream reverse osmosis water pipeline L11 to discharge the water stored in the water supply tank T10, and a drain valve V15 is installed on the drain pipeline L111.
[0026] The upstream sides of the downstream reverse osmosis water pipelines L12 and L13 are connected to the bottom of the constant water level section T10a of the water supply tank T10. Flow meters FS12 and FS13, and water supply valves V12 and V13 are respectively installed on the downstream reverse osmosis water pipelines L12 and L13. Flow meters FS12 and FS13 measure the flow rate of water flowing in the downstream reverse osmosis water pipelines L12 and L13, respectively. Water supply valves V12 and V13 open and close the flow paths of the downstream reverse osmosis water pipelines L12 and L13, respectively.
[0027] The chemical solution pipeline L2 supplies disinfectant, cleaning solution, and other chemicals to the reverse osmosis water pipeline L1. In this embodiment, the chemical solution pipeline L2 supplies chemicals to the downstream reverse osmosis water pipelines L12 and L13 via the water supply tank T10. More specifically, the downstream side of the chemical solution pipeline L2 is connected to the delivery pipeline L10 of the water supply tank T10. A chemical solution pump P20 and a chemical solution valve V20 are installed on the chemical solution pipeline L2.
[0028] The chemical pump P20 delivers the chemical solution flowing in the chemical solution pipeline L2 to the downstream reverse osmosis water pipelines L12 and L13 via the delivery pipeline L10 and the water supply tank T10. The chemical valve V20 opens and closes the chemical solution pipeline L2.
[0029] Stock solution tanks T31 and T32 store different types of dialysis stock solutions, respectively. In this embodiment, stock solution B, which is a dialysis stock solution, is stored in stock solution tank T31, and stock solution A, which is a dialysis stock solution, is stored in stock solution tank T32. Examples of stock solution A include those containing sodium chloride, potassium chloride, calcium chloride, magnesium chloride, sodium acetic anhydride, glucose, etc. Examples of stock solution B include those containing sodium bicarbonate, etc.
[0030] The raw liquid pipeline L3 has a first raw liquid pipeline L31 connected to the raw liquid tank T31 on the upstream side and the mixer 60 on the downstream side, and a second raw liquid pipeline L32 connected to the raw liquid tank T32 on the upstream side and the mixer 60 on the downstream side.
[0031] One-way valves V31 and V32, and raw material pumps P31 and P32 are respectively installed on the first raw material pipeline L31 and the second raw material pipeline L32. One-way valves V31 and V32 are located near the raw material tanks T31 and T32 in the first and second raw material pipelines L31 and L32, respectively. One-way valves V31 and V32 prevent liquid from flowing into the raw material tanks T31 and T32 in the first and second raw material pipelines L31 and L32.
[0032] The feedstock pumps P31 and P32 are pumps capable of both forward and reverse rotation. When the feedstock pumps P31 and P32 are rotated forward, liquid is discharged to the mixer 60 side through the first feedstock line L31 and the second feedstock line L32. When the feedstock pumps P31 and P32 are rotated in reverse, liquid is discharged to the feedstock tanks T31 and T32 through the first feedstock line L31 and the second feedstock line L32.
[0033] The drain line L4 has a first drain line L41 connected to the first raw liquid line L31 and a second drain line L42 connected to the second raw liquid line L32.
[0034] The first drain line L41 connects the one-way valve V31 in the first feed line L31 to the feed pump P31. In other words, the one-way valve V31 is located in the first feed line L31 closer to the feed solution supply side (feed solution tank T31 side) than the connection point with the first drain line L41. A drain valve V41 is installed in the first drain line L41. The drain valve V41 opens and closes the first drain line L41.
[0035] The second drain line L42 connects the one-way valve V32 in the second feed line L32 to the feed pump P32. In other words, the one-way valve V32 is located in the second feed line L32 closer to the feed side (feed tank T32 side) than the connection point with the second drain line L42. A drain valve V42 is installed on the second drain line L42. The drain valve V42 opens and closes the second drain line L42.
[0036] The mixer 60 is positioned below the water supply tank T10 and is configured to uniformly mix stock solution B and stock solution A into the RO water supplied from the water supply tank T10 via differential pressure. Specifically, the mixer 60 includes a first mixing section 61 for mixing RO water with stock solution B, a second mixing section 62 for mixing the RO water mixed by the first mixing section 61 with stock solution B and stock solution A, and an outlet pipe 63 connecting the first mixing section 61 and the second mixing section 62.
[0037] The dialysate tank T50 stores the dialysate generated in the mixer 60. Level sensors LS51, LS52, and LS53 are installed in the dialysate tank T50. Level sensors LS51, LS52, and LS53 detect the level of the dialysate stored in the dialysate tank T50.
[0038] The dialysate supply line L5 supplies the dialysate generated in the mixer 60 to the outside. The dialysate supply line L5 includes a first dialysate supply line L51 connecting the mixer 60 (second mixing unit 62) to the dialysate tank T50, and a second dialysate supply line L52 connecting the dialysate tank T50 to a dialysis device, which is the destination of the dialysate supply.
[0039] The first dialysate supply line L51 supplies the dialysate generated in the mixer 60 to the dialysate tank T50. A dialysate supply valve V51 is installed on the first dialysate supply line L51. The dialysate supply valve V51 opens and closes the first dialysate supply line L51.
[0040] The second dialysate supply line L52 supplies dialysate stored in the dialysate tank T50 to the dialysis apparatus, etc. A delivery pump P50 is installed on the second dialysate supply line L52. The delivery pump P50 delivers the dialysate stored in the dialysate tank T50.
[0041] The control device 70 consists of a microcomputer and the like that operates according to a prescribed program. The control device 70 detects signals input from various sensors such as flow meters FS12 and FS13, water level sensors LS11 and LS12, liquid level sensors LS51, LS52 and LS53, as well as operator operations, and controls various pumps and valves such as the water supply shut-off valve V10, water supply pump P10, chemical solution pump P20, chemical solution valve V20, delivery pump P50, raw material pump P31 and P32, drain valve V41 and V42, and dialysate supply valve V51 based on these signals.
[0042] Specifically, the control device 70 controls the stock solution pumps P31 and P32 to adjust the injection volume of stock solution B and stock solution A in such a way that the generated dialysate has a certain mixing ratio.
[0043] In addition, the control device 70 controls the operation of various pumps and valves, and switches the operation mode of the dialysate supply device 1 to dialysate generation operation mode, pre-cleaning operation mode, disinfection operation mode, acid cleaning operation mode, and post-cleaning and discharge operation mode.
[0044] Among these operating modes, the dialysate generation operating mode, the disinfection operating mode for purifying each pipeline, and the acid cleaning operating mode involved in this embodiment are described in detail.
[0045] like Figure 1 As shown, in the dialysate generation operation mode, the control device 70 opens the water supply shut-off valve V10, the first water supply valve V12, the second water supply valve V13, and the dialysate supply valve V51, while closing the drain valve V15, the drug solution valve V20, and the drain valves V41 and V42. Furthermore, the water supply pump P10 is activated, and the feedstock pumps P31 and P32 rotate forward. As a result, RO water and feedstock B are mixed in the first mixing section 61, and then feedstock A is mixed in the second mixing section 62 with the mixture of RO water and feedstock B from the first mixing section 61, generating dialysate mixed at a predetermined mixing ratio. In the dialysis apparatus, during dialysis treatment where dialysate must be supplied, the dialysate supply device 1 operates according to the dialysate generation operation mode, continuously generating and supplying dialysate.
[0046] The disinfection operation mode is a mode in which the reverse osmosis water pipeline L1, the first raw solution pipeline L31, and the second raw solution pipeline L32 are disinfected with disinfectant. In the disinfection operation mode, the upstream side of the chemical solution pipeline L2 is connected to the disinfectant supply source.
[0047] like Figure 3As shown, in the disinfection operation mode, the control device 70 opens the water supply shut-off valve V10, the chemical solution valve V20, and the drain valves V41 and V42, while closing the drain valve V15 and the dialysate supply valve V51. Furthermore, the water supply pump P10 and the chemical solution pump P20 are activated. As a result, the disinfectant solution, acting as a chemical solution, is supplied to the water supply tank T10 via the delivery pipeline L10, and RO water is also supplied to the water supply tank T10, where the disinfectant solution mixes with the RO water to generate disinfectant. Additionally, the raw material pumps P31 and P32 are reversed. Through this control, the generated disinfectant flows into the first raw material pipeline L31 and the second raw material pipeline L32 via the first mixing section 61 and the second mixing section 62, respectively, and is discharged via the first drain pipeline L41 and the second drain pipeline L42, respectively. In addition, at this time, one-way valves V31 and V32 are used to prevent disinfectant from flowing into the stock solution tank T31 and stock solution tank T32.
[0048] In addition, the dialysate tank T50 and dialysate supply line L5 can be disinfected by opening the dialysate supply valve V51 and activating the dialysate pump P50.
[0049] The acid cleaning operation mode is a mode in which reverse osmosis water pipeline L1, first raw solution pipeline L31, and second raw solution pipeline L32 are cleaned with acid cleaning solution. In the acid cleaning operation mode, the upstream side of the chemical solution pipeline L2 is connected to the acid cleaning solution supply source. The only difference is that the chemical solution connected to the chemical solution pipeline L2 is changed from disinfectant to acid cleaning solution. The control method of the control device 70 in the acid cleaning operation mode is the same as that in the disinfection operation mode.
[0050] The dialysate supply device 1 of this embodiment, as described above, has the following effects.
[0051] (1) The dialysate supply device 1 includes: a reverse osmosis water pipeline L1 for supplying reverse osmosis water, a raw material pipeline L3 for supplying dialysate, a mixer 60 for mixing reverse osmosis water and dialysate to generate dialysate, a dialysate supply pipeline L5 connected to the mixer 60 and supplying the generated dialysate, a drug supply pipeline L2 for supplying the drug solution to the reverse osmosis water pipeline L1, a drain pipeline L4 connected to the raw material pipeline L3, raw material pumps P31 and P32 installed in the raw material pipeline L3 and capable of forward and reverse rotation, and a connection part installed in the raw material pipeline L3 to the drain pipeline L4. The system comprises one-way valves V31 and V32 closer to the supply side of the dialysis feed solution, drain valves V41 and V42 located in the drain line L4, a drug solution valve V20 located in the drug solution line L2, and a control device 70. The control device 70 controls the following: when generating dialysis feed solution, it rotates the feed solution pumps P31 and P32 forward and closes the drug solution valves V20 and V41 and V42; when cleaning or disinfecting the dialysis feed solution supply device 1, it reverses the flow of the feed solution pumps P31 and P32 and opens the drug solution valves V20 and V41 and V42. Thus, when disinfecting or cleaning the dialysis feed solution supply device 1, the reverse osmosis water mixed with the drug solution flows through the mixer 60 and the feed solution lines L31 and L32, and is then discharged through the drain lines L41 and L42. Furthermore, at this time, one-way valves V31 and V32 prevent reverse osmosis water mixed with the drug solution from flowing into the raw material tanks T31 and T32. Therefore, there is no need to install separate disinfection and cleaning pipelines to purify the raw material pipeline L3.
[0052] (2) Furthermore, the device is configured to include a water supply tank T10 connected to the upstream side of the reverse osmosis water pipeline L1 and storing reverse osmosis water. A chemical solution pipeline L2 is connected to the bottom of the water supply tank T10, and chemical solution is supplied to the reverse osmosis water pipeline L1 via the water supply tank T10. Thus, when disinfecting or cleaning the dialysate supply device 1, chemical solution and RO water can be mixed and generated in the water supply tank T10, thereby enabling appropriate disinfection or cleaning of the dialysate supply device 1.
[0053] Furthermore, by connecting the chemical solution pipeline L2 to the bottom of the water supply tank T10 (supply pipeline L10), it is possible to effectively prevent the chemical solution from mixing into the water supply tank T10 from the chemical solution pipeline L2 when generating dialysate. That is, by positioning the chemical solution pipeline L2, which supplies disinfectant to the water supply tank T10, below the water supply tank T10, it is possible to prevent the disinfectant from mixing into the water supply tank T10 due to gravity when generating dialysate in which it is undesirable to contain disinfectant.
[0054] The preferred embodiments of the dialysis fluid supply device of the present invention have been described above, but the present invention is not limited to the above embodiments and can be appropriately modified.
[0055] For example, in this embodiment, as an example, a structure is shown in which a water supply tank is installed on the reverse osmosis water pipeline L1, but it is not limited to this. For example, it is also possible to configure the system so that no water supply tank is installed on the reverse osmosis water pipeline, and RO water is supplied directly to the mixer.
[0056] [Explanation of reference numerals in the attached figures]
[0057] 1. Dialysis fluid supply device
[0058] 60 Mixer
[0059] L1 reverse osmosis water pipeline
[0060] L2 drug solution pipeline
[0061] L3 raw material pipeline
[0062] L4 drain line
[0063] L5 dialysate supply line
[0064] P31 raw material pump
[0065] P32 raw material pump
[0066] P50 liquid delivery pump
[0067] T50 Dialysis Fluid Box
[0068] V20 medicine valve
[0069] V31 check valve
[0070] V32 check valve
[0071] V41 drain valve
[0072] V42 drain valve
Claims
1. A dialysate supply device comprising: a reverse osmosis water line that supplies reverse osmosis water; a primary solution line that supplies a dialysis primary solution; a mixer that is connected to the reverse osmosis water line and the primary solution line, and that mixes the reverse osmosis water and the dialysis primary solution to produce a dialysate; a dialysate supply line that is connected to the mixer and that supplies the produced dialysate; a medicine solution line that supplies a medicine solution to the reverse osmosis water line; a drain line that is connected to the primary solution line; a primary solution pump that is configured in the primary solution line and that is capable of forward rotation and reverse rotation; a check valve that is configured in the primary solution line at a position closer to a supply side of the dialysis primary solution than a connection portion with the drain line; a drain valve that is configured in the drain line; a medicine solution valve that is configured in the medicine solution line; and a control device, the primary solution pump is configured in the primary solution line at a position closer to the mixer than the connection portion with the drain line, for the control device, in a case where the dialysate is produced, the primary solution pump is caused to rotate forward and the medicine solution valve and the drain valve are caused to close, and in a case where the dialysate supply device is sterilized or cleaned, the primary solution pump is caused to rotate reverse and the medicine solution valve and the drain valve are caused to open.
2. The dialysate supply device according to claim 1, further comprising a water supply tank that stores the reverse osmosis water, the water supply tank being connected to an upstream side of the reverse osmosis water line, the medicine solution line being connected to a bottom portion of the water supply tank, and the medicine solution line supplying the medicine solution to the dialysate supply line via the water supply tank.
Citation Information
Patent Citations
Method for washing dialysis apparatus
JP2001009029A
Dialysis fluid feeding device
JP2014184064A