Thrombus fragmentation device and thrombus suction catheter thereof

Abstract

The present invention provides a thrombus fragmentation device and its thrombus aspiration catheter, relating to the field of medical device technology. The thrombus fragmentation device includes a first cannula and a second cannula that can be extended into the location of the thrombus within a blood vessel. The second cannula is axially movable within the cavity of the first cannula. A toggle lever is provided on the outer wall of each of the first and second cannulae. When breaking the thrombus, the first and second cannulae rotate in opposite directions carrying the toggle lever. The first and second cannulae of the present invention rotate in opposite directions, thereby achieving a better fragmentation effect and avoiding the drawback of limited "crushing" capability when simply using balloon dilation to "crush" large thrombi.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a thrombus fragmentation device and a thrombus suction catheter thereof. Background Art

[0002] Coronary atherosclerotic heart disease (CHD) is a major health issue, with high morbidity and mortality. Acute myocardial infarction (AMI) is a severe manifestation of CHD, the pathogenesis of which is coronary artery stenosis combined with thrombosis.

[0003] Interventional treatment of coronary heart disease is currently the main method for treating coronary heart disease. The basic principle of percutaneous coronary intervention is to puncture a peripheral artery (radial artery in the hand or femoral artery in the thigh), insert an arterial sheath, and then send an angiographic guidewire through the sheath. Then, the coronary guide catheter is sent to the opening of the coronary artery through the angiographic guidewire. After the catheter is in place, the guide wire for treatment is sent through the inner lumen of the catheter through the tortuous blood vessels to the distal part of the blood vessel to establish a track. Then, a balloon for dilating the blood vessels and a stent for further treatment are sent through the guidewire. For lesions with coronary thrombosis, we can use a thrombus aspiration catheter to aspirate the thrombus clinically, and then perform stent implantation. This can significantly improve the possibility of adverse reactions after stent implantation in patients with acute myocardial infarction.

[0004] The catheter used for thrombus aspiration is called a thrombus aspiration catheter. Although traditional thrombus aspiration catheters look different, they are basically hollow catheters at their core. An external negative pressure syringe is used to aspirate through the catheter tip or side hole. A significant drawback of the thrombus aspiration catheters currently used clinically is their inability to aspirate large clots. For patients with a heavy thrombus burden, repeated aspiration with the thrombus aspiration catheter is also very limited in effect, and large clots may even cause catheter blockage. In clinical practice, we often use balloon dilatation to "crush" large clots, but the "crushing" ability is limited.

[0005] Therefore, how to improve the ability to "crush" blood clots has become a technical problem that needs to be urgently solved by those skilled in the art. Summary of the Invention

[0006] In view of this, one of the objectives of the present invention is to provide a thrombus fragmentation device to solve the technical problem of limited "crushing" ability when using balloon dilation method to "crush" large thrombi in the prior art.

[0007] A second object of the present invention is to provide a thrombus aspiration catheter containing the above-mentioned thrombus fragmentation device.

[0008] In order to achieve one of the above-mentioned purposes, the present invention provides a thrombus breaking device, comprising a first sleeve and a second sleeve that can be extended into the position of the thrombus in the blood vessel, the second sleeve being movably arranged in the cavity of the first sleeve along the axial direction, and a toggle rod being provided on the outer wall of the first sleeve and the outer wall of the second sleeve. When breaking the thrombus, the first sleeve and the second sleeve carry the toggle rod to rotate in opposite directions.

[0009] According to a preferred embodiment, the driving force for the rotation of the first sleeve and the second sleeve is manual force.

[0010] According to a preferred embodiment, the handheld ends of the first sleeve and the second sleeve are provided with friction protrusions.

[0011] According to a preferred embodiment, the side wall of the second sleeve is a hollow structure.

[0012] According to a preferred embodiment, the hollow structure is an elliptical hole or a circular hole.

[0013] According to a preferred embodiment, a first inflation conduit is provided on the outer wall of the first sleeve, the first inflation conduit is arranged along the axial direction of the first sleeve, and an extrusion airbag is provided at the end of the first inflation conduit.

[0014] According to a preferred embodiment, an air pump may be installed on the end of the first inflation conduit opposite to the extrusion airbag.

[0015] In order to achieve the second of the above objectives, the present invention provides a thrombus aspiration catheter, comprising any of the above-mentioned thrombus breaking devices, and also comprising a tube body, wherein the thrombus breaking device can be movably installed in the cavity of the tube body.

[0016] According to a preferred embodiment, the end of the tube placed in the blood vessel is configured as an oblique opening.

[0017] According to a preferred embodiment, a second inflation conduit is provided on the outer wall of the tube body, the second inflation conduit is arranged along the axial direction of the tube body, and an embolization balloon is provided at the end of the second inflation conduit.

[0018] The thrombus fragmentation device provided by the present invention has the following technical effects:

[0019] This thrombus-breaking device is used to break up thrombi in blood vessels and is mainly composed of a first sleeve and a second sleeve. The first sleeve and the second sleeve can be extended into the interior of the blood vessel to reach the position containing the thrombus. The second sleeve is movably sleeved in the cavity of the first sleeve along the axial direction. The outer wall of the first sleeve and the outer wall of the second sleeve are both provided with a toggle rod. When breaking the thrombus, the first sleeve and the second sleeve carry the toggle rod to rotate in opposite directions, that is, the toggle rod on the first sleeve and the toggle rod on the second sleeve to toggle large thrombi to achieve the purpose of breaking. Since the first sleeve and the second sleeve rotate in opposite directions, the large thrombi can be broken from opposite directions, and the breaking effect is better, avoiding the defect of limited "crushing" ability when simply using the balloon dilation method to "crush" large thrombi.

[0020] The embolus suction catheter provided by the present invention has the following technical effects:

[0021] This type of thrombus aspiration catheter includes a thrombus breaking device and a tube body. The thrombus breaking device can be movably installed in the cavity of the tube body. The thrombus breaking device and the tube body are extended into the blood vessel together, and the thrombus breaking device is used to achieve the purpose of efficiently breaking the thrombus. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0023] Figure 1 1 is a schematic structural diagram of a thrombus fragmentation device according to an embodiment of the present invention;

[0024] Figure 2 yes Figure 1 Schematic diagram of the structure of the second sleeve inside the thrombus fragmentation device;

[0025] Figure 3 This is a schematic structural diagram of an embolus aspiration catheter according to an embodiment of the present invention;

[0026] Figure 4 Schematic diagram of a blood vessel in the body containing a thrombus.

[0027] in, Figures 1-4 :

[0028] 1. First sleeve; 11. Toggle lever; 12. Friction protrusion; 2. Second sleeve; 21. Toggle lever; 22. Friction protrusion; 23. Hollow structure; 3. First inflation catheter; 31. Extrusion balloon; 4. Tube body; 5. Second inflation catheter; 51. Embolization balloon; 6. Radial artery; 7. Aorta; 8. Cardiac blood vessels; 81. Thrombus; 9. Guidewire. DETAILED DESCRIPTION

[0029] To make the objectives, technical solutions, and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other implementations obtained by those of ordinary skill in the art without inventive effort are within the scope of protection of the present invention.

[0030] In the description of the present invention, it should be noted that, unless otherwise specified, "plurality" means two or more; the terms "upper," "lower," "left," "right," "inner," "outer," "front end," "rear end," "head," "tail," etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings and are intended only to facilitate the description of the present invention and simplify the description. They do not indicate or imply that the devices or components referred to must have a specific direction, be constructed, or operate in a specific direction, and therefore should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0031] It should also be noted that, in the description of the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" should be understood broadly. For example, they may refer to fixed, detachable, or integral connections; mechanical or electrical connections; and direct or indirect connections through an intermediary. Those skilled in the art will understand the specific meanings of the above terms in the present invention depending on the specific circumstances.

[0032] As described in the background, existing embolus aspiration catheters, while different in appearance, are essentially hollow catheters. An external negative pressure syringe is connected to the catheter tip or side port for suction. A significant drawback of current clinically used embolus aspiration catheters is their inability to aspirate large clots. For patients with heavy thrombus burden, repeated aspiration with the catheter is also very ineffective and may even cause catheter blockage. Balloon dilatation is often used clinically to crush large clots, but this ability is limited.

[0033] Based on this, the present invention provides a thrombus fragmentation device for fragmenting thrombi in blood vessels, which is mainly composed of a first sleeve and a second sleeve. The first sleeve and the second sleeve can be extended into the interior of the blood vessel to reach the position containing the thrombus. The second sleeve is movably sleeved in the cavity of the first sleeve along the axial direction. The outer wall of the first sleeve and the outer wall of the second sleeve are both provided with a toggle rod. When breaking the thrombus, the first sleeve and the second sleeve carry the toggle rod to rotate in opposite directions, that is, the toggle rod on the first sleeve and the toggle rod on the second sleeve are used to toggle large thrombi to achieve the purpose of fragmentation. Since the first sleeve and the second sleeve rotate in opposite directions, the large thrombi can be fragmented from opposite directions, and the fragmentation effect is better, avoiding the defect of limited "crushing" ability when simply using the balloon dilation method to "crush" large thrombi.

[0034] The following is combined with specific Figure 1-4 The technical solution of the present invention is described in detail.

[0035] The thrombus breaking device provided by the present invention is mainly used to break up the thrombus 81 in the blood vessel, replacing the traditional method of simply using balloon dilation to "crush" the large thrombus 81.

[0036] like Figure 1 and Figure 2 As shown, the thrombus fragmentation device of the present invention includes a first sleeve 1 and a second sleeve 2. The first sleeve 1 and the second sleeve 2 can both be extended into the position containing the thrombus 81 in the blood vessel. The radius of the first sleeve 1 is larger than the radius of the second sleeve 2. The second sleeve 2 is movably sleeved in the cavity of the first sleeve 1 along the axial direction, that is, the second sleeve 2 can slide back and forth in the axial direction on the first sleeve 1, and can also rotate back and forth along the radial direction.

[0037] like Figure 1 and Figure 2 As shown, the outer walls of the first sleeve 1 and the outer walls of the second sleeve 2 are both provided with toggle rods 11, 21. The toggle rods 11, 21 are integrally formed with the first sleeve 1 and the second sleeve 2 and have a certain degree of flexibility. The toggle rods 11, 21 can toggle the thrombus 81 with a certain viscosity in the blood vessel.

[0038] When the thrombus breaking device is inserted into the lumen of the blood vessel carrying the thrombus 81 , the insertion is performed through the guide wire 9 . This insertion method is relatively common and will not be described in detail in the present invention.

[0039] The first sleeve 1 and the second sleeve 2 rotate in opposite directions. When the first sleeve 1 rotates counterclockwise, the second sleeve 2 rotates clockwise, or when the first sleeve 1 rotates clockwise, the second sleeve 2 rotates counterclockwise. The rotation directions of the two sleeves are inconsistent, that is, the thrombus 81 is broken from two opposite directions, which has a higher breaking efficiency.

[0040] It should be noted that the driving force for the rotation of the first cannula 1 and the second cannula 2 is manually applied. The left hand and the right hand each hold a cannula, and the two hands rotate the cannula in opposite directions. The rotation speed and rotation force are determined according to the size of the patient's thrombus 81. This operation is performed by the attending physician.

[0041] In order to increase the friction when holding the first sleeve 1 and the second sleeve 2 to prevent slipping, Figure 1 and Figure 2 As shown, the handheld ends of the first sleeve 1 and the second sleeve 2 are provided with friction protrusions 12, 22. The friction protrusions 12, 22 are preferably of a goose egg-like structure, but are not limited to this structure. As long as the purpose of increasing friction can be achieved, it is within the protection scope of the present invention.

[0042] Furthermore, the side wall of the second cannula 2 is a hollow structure 23, and the hollow structure 23 is preferably an elliptical hole or a circular hole. The end of the second cannula 2 placed outside the body can be connected to a negative pressure suction pump. When the negative pressure suction pump is started, the broken small pieces of thrombus 81 are sucked into the second cannula 2 through the hollow structure 23, so that the broken thrombus 81 is sucked outward through the second cannula 2.

[0043] In addition to the above-mentioned efficient method of breaking up the thrombus 81 , the thrombus breaking device of the present invention also adds a balloon dilatation method to “crush” the large thrombus 81 .

[0044] Specifically, such as Figure 1 As shown, a first inflation tube 3 is provided on the outer wall of the first cannula 1. The first inflation tube 3 is arranged along the axial direction of the first cannula 1. An extrusion airbag 31 is provided at the end of the first inflation tube 3. That is, the extrusion airbag 31 is inflated through the first inflation tube 3. After the extrusion airbag 31 is inflated, it can squeeze the large thrombus 81 in the blood vessel. The extrusion crushing method of the extrusion airbag 31 and the rotational crushing method of the first cannula 1 and the second cannula 2 are not prioritized. The two work together to achieve the purpose of breaking the large thrombus 81 into small thrombus 81.

[0045] The extrusion airbag 31 is inflated by an air pump through the first inflation conduit 3 , and the air pump can be installed on the end of the first inflation conduit 3 opposite to the extrusion airbag 31 .

[0046] On the other hand, the present invention also provides a thrombus suction catheter, such as Figure 3 As shown, it includes the above-mentioned thrombus breaking device and a tube body 4, and the thrombus breaking device can be movably installed in the cavity of the tube body 4.

[0047] The tube body 4 of the present invention is a conventional thrombus aspiration catheter in the prior art. The difference from the thrombus aspiration catheter in the prior art is that the present invention adds a thrombus crushing device on the basis of the original thrombus aspiration catheter. After the above-mentioned thrombus crushing device completes the thrombus 81 crushing action in the blood vessel, the thrombus aspiration catheter still needs to perform the next thrombus aspiration operation, that is, the end of the tube body 4 of the present invention can be used to connect a negative pressure suction pump.

[0048] In order to increase the contact area with the thrombus 81 and facilitate passing through tortuous blood vessels, such as Figure 3 As shown, one end of the tube body 4 placed in the blood vessel is configured with an oblique opening.

[0049] Furthermore, in order to prevent the large thrombus 81 from being "crushed" by the balloon dilation method, the crushed thrombus 81 is likely to fall to the distal end of the blood vessel, causing the defect of infarction at the distal end of the blood vessel, such as Figure 3 As shown, a second inflation catheter 5 is provided on the outer wall of the tube body 4. The second inflation catheter 5 is arranged along the axial direction of the tube body 4. An embolic airbag 51 is provided at the end of the second inflation catheter 5. The second inflation catheter 5 can be connected to an inflation pump, and the embolic airbag 51 is inflated by the inflation pump. During the entry process, the inflation pump is not started. After the embolic airbag 51 reaches the specified position, the inflation pump is started, and the volume of the embolic airbag 51 increases. The increased volume is used to prevent infarction at the distal end of the blood vessel.

[0050] like Figure 4 As shown, the vascular structure of the human body includes the heart vessel 8, the aorta 7 and the radial artery 6 on the arm. During the operation, the doctor first inserts the guide wire 9 into the radial artery 6, passes through the aorta 7, and reaches the heart vessel 8. The thrombus breaking device and the tube body 4 are guided by the guide wire 9 to the thrombus 81 in the heart vessel 8. The thrombus breaking device is used to break the thrombus 81, and the broken thrombus 81 is sucked out of the body by a negative pressure suction pump.

[0051] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any modifications or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present invention should be included in the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be based on the scope of protection of the claims.

Claims

1. A thrombus fragmentation device, characterized in that: The device comprises a first cannula and a second cannula that can be extended into the location of a thrombus in a blood vessel. The second cannula is movably sheathed in the cavity of the first cannula along the axial direction. A toggle lever is provided on the outer wall of each of the first and second cannulae. When the thrombus is broken, the first and second cannulae carry the toggle lever to rotate in opposite directions. The driving force for the rotation of the first and second cannulae is manually applied. The handheld ends of the first sleeve and the second sleeve are provided with friction protrusions.

2. The thrombus fragmentation device according to claim 1, characterized in that: The side wall of the second sleeve is a hollow structure.

3. The thrombus fragmentation device according to claim 2, characterized in that: The hollow structure is an elliptical hole or a circular hole.

4. The thrombus fragmentation device according to claim 1, characterized in that: A first inflation conduit is provided on the outer wall of the first sleeve, and the first inflation conduit is arranged along the axial direction of the first sleeve. An extrusion airbag is provided at the end of the first inflation conduit.

5. The thrombus fragmentation device according to claim 4, characterized in that: An air pump may be installed on the end of the first inflation conduit opposite to the extrusion airbag.

6. A thrombus suction catheter, characterized in that: The thrombus-breaking device comprises the thrombus-breaking device according to any one of claims 1 to 5, and further comprises a tubular body, wherein the thrombus-breaking device can be movably installed in the cavity of the tubular body.

7. The embolus aspiration catheter according to claim 6, characterized in that: One end of the tube body placed in the blood vessel is configured as an oblique opening.

8. The embolus aspiration catheter according to claim 6, characterized in that: A second inflation catheter is provided on the outer wall of the tube body. The second inflation catheter is arranged along the axial direction of the tube body. An embolization airbag is provided at the end of the second inflation catheter.

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