Thrombus aspiration catheter
By setting a pressure relief hole and a sealing component at the distal end of the thrombus aspiration catheter, the problem of "biting into the wall" during catheter startup is solved, achieving stability and safety of suction force, avoiding vascular damage, and improving aspiration efficiency.
Patent Information
- Application Number
- CN202511295219.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-11
- Publication Date
- 2025-12-02
AI Technical Summary
Existing thrombus aspiration catheters can cause vascular damage due to the concentrated suction force during initiation, resulting in a "wall-biting" phenomenon that increases the risk of surgical complications.
A pressure relief hole and a sealing component are set at the distal end of the catheter body. The pressure relief hole disperses the instantaneous negative pressure, and the sealing component dynamically controls the pressure relief state to ensure the stability of the suction force.
It effectively reduces the adhesion of the distal end of the catheter to the blood vessel wall, reduces intimal tearing and perforation, and improves surgical safety and aspiration efficiency.
Smart Images
Figure CN121040995A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of interventional device technology, specifically relating to a thrombus aspiration catheter. Background Technology
[0002] In the clinical treatment of acute thrombotic diseases, thrombectomy, as a minimally invasive interventional treatment technique, has become a key means to quickly relieve vascular blockage and save patients' lives due to its advantages of not requiring surgery, minimal trauma, and rapid recovery. This procedure uses specialized instruments to directly remove thrombi formed within blood vessels, thereby rapidly restoring blood flow to the affected area, minimizing necrosis of vital organs caused by ischemia, and reducing long-term disability and mortality rates. It is widely used in the emergency treatment of diseases such as acute myocardial infarction, acute ischemic stroke, and acute lower extremity arterial embolism.
[0003] However, currently used thrombectomy catheters have significant technical defects in actual operation, directly affecting surgical safety and treatment outcomes. Specifically, when traditional thrombectomy catheters are in operation, the distal aspiration port directly contacts the inner wall of the blood vessel. This means that during the initial startup phase of the aspiration device (such as a negative pressure pump), due to the lack of a buffer mechanism between the catheter aspiration port and the blood vessel wall, the negative pressure effect at the moment of device startup is directly concentrated at the contact point. Because the local cavity at the distal end of the catheter is extremely small, the instantaneous negative pressure will form a highly concentrated suction force at the contact point, which can easily cause the "wall biting" phenomenon (i.e., the catheter port tightly adheres to the blood vessel wall). This not only fails to effectively aspirate thrombi but may also cause mechanical damage such as tearing of the vascular intima and perforation of the blood vessel wall. In severe cases, it can even lead to vascular dissection and distal vascular embolism (blood vessel wall fragments or thrombus particles that break off during the aspiration process block downstream capillaries with the blood flow), increasing the risk of surgical complications.
[0004] To address these issues, current methods typically improve the situation by optimizing the initial negative pressure parameters of the aspiration device (e.g., reducing the initial suction force upon device startup). However, this approach is limited by the instrument characteristics and physiological environment of thrombectomy, making it difficult to achieve the desired results. The main reason is that thrombectomy catheters, designed to meet the treatment needs of different vascular sites, are usually several tens of centimeters to 2 meters in length. The slender catheter lumen generates significant fluid resistance. Simultaneously, factors such as blood viscosity and the elastic deformation of the connecting tubing of the aspiration device cause significant delays and attenuation of the externally set negative pressure value during its transmission to the distal end of the catheter. This means that adjusting the external negative pressure cannot precisely match the actual pressure requirements at the moment of contact between the catheter opening and the vessel wall. Specifically, insufficient aspiration efficiency may result from delayed negative pressure transmission upon initial contact, or a sudden increase in local pressure may occur due to uneven negative pressure attenuation. Ultimately, the risk of vessel wall damage and aspiration stability issues cannot be completely eliminated.
[0005] Therefore, there is a need to provide an improved technical solution that addresses the shortcomings of the existing technology. Summary of the Invention
[0006] The purpose of this invention is to provide a thrombus aspiration catheter to solve the technical problem that existing thrombus aspiration catheters are prone to "wall biting" and causing vascular damage due to the concentration of instantaneous suction force when started.
[0007] To achieve the above objectives, the thrombus aspiration catheter of the present invention provides the following technical solution:
[0008] A thrombus aspiration catheter includes a catheter body, a suction device connected to the proximal end of the catheter body, and a pressure relief port provided at the distal end to reduce the instantaneous suction force of the catheter body. The distal end of the catheter body is also provided with a sealing component for sealing the pressure relief port to control the pressure relief state of the pressure relief port and ensure the stability of the suction force of the catheter body.
[0009] As a further optimized technical solution, multiple pressure relief holes are arranged at intervals along the axial and / or circumferential direction of the conduit body.
[0010] As a further optimized technical solution, the sealing component is a sliding sleeve, which slides in conjunction with the distal end of the catheter body to control the degree of sealing of the pressure relief hole.
[0011] As a further optimized technical solution, the sliding sleeve is provided with a driving component for driving the sliding sleeve to slide along the guide tube body.
[0012] As a further optimized technical solution, a sliding groove is arranged inside the wall of the catheter body, and the sliding sleeve is arranged inside the sliding groove.
[0013] As a further optimized technical solution, the driving component is a driving guidewire, the distal end of which is fixedly connected to the proximal end of the sliding sleeve, and the proximal end extends to the outside along the catheter body.
[0014] As a further optimized technical solution, two drive guide wires are arranged symmetrically in the radial direction.
[0015] As a further optimized technical solution, the catheter body has an axially extending sliding channel arranged on its wall, and the drive guidewire is arranged along the sliding channel.
[0016] As a further optimized technical solution, the pressure relief holes are arranged in multiple rows at intervals along the axial direction, and each row of pressure relief holes is arranged in multiple rows at intervals along the circumferential direction.
[0017] As a further optimized technical solution, any two adjacent rows of pressure relief holes are staggered.
[0018] Beneficial effects: This invention, by setting a pressure relief hole at the distal end of the catheter body, disperses the instantaneous negative pressure at the initial stage of aspiration, effectively reducing the suction force of the distal end of the catheter on the blood vessel wall, reducing mechanical damage such as intimal tearing and perforation, and improving surgical safety. Simultaneously, this invention achieves dynamic control of the pressure relief state of the pressure relief hole through a sealing component, allowing flexible adjustment of the negative pressure intensity within the catheter body according to the aspiration stage: at the initial stage, the sealing component does not seal the pressure relief hole, effectively reducing the instantaneous suction force at the distal end of the thrombus aspiration catheter and preventing the distal end of the catheter from "biting" the wall. After the aspiration device stabilizes and the airflow becomes stable, the sealing component seals the pressure relief hole to ensure the stability of the suction force of the catheter body, thereby ensuring the effectiveness and efficiency of thrombus aspiration. Attached Figure Description
[0019] The accompanying drawings, which form part of this application, are used to provide a further understanding of the invention. The illustrative embodiments of the invention and their descriptions are used to explain the invention and do not constitute an undue limitation of the invention. Wherein:
[0020] Figure 1 This is a schematic diagram of the distal structure of Embodiment 1 of the thrombus aspiration catheter of the present invention;
[0021] Figure 2 This is a schematic cross-sectional view of the distal structure of Embodiment 1 of the thrombus aspiration catheter of the present invention;
[0022] Figure 3 This is a schematic cross-sectional view of the distal structure of Embodiment 2 of the thrombus aspiration catheter of the present invention;
[0023] Figure 4 This is a schematic cross-sectional view of the distal structure of Embodiment 3 of the thrombus aspiration catheter of the present invention.
[0024] In the figure: 100, catheter body; 110, sliding groove; 120, sliding channel; 200, pressure relief hole; 300, sealing component; 400, drive guide wire. Detailed Implementation
[0025] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention are within the scope of protection of the present invention.
[0026] In the description of this invention, the terms "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," and "bottom," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and do not require the invention to be constructed and operated in a specific orientation; therefore, they should not be construed as limitations on the invention. The terms "connected" and "linked" used in this invention should be interpreted broadly. For example, they can refer to a fixed connection or a detachable connection; they can refer to a direct connection or an indirect connection through intermediate components. Those skilled in the art can understand the specific meaning of the above terms according to the specific circumstances. Furthermore, the term "proximal end" uniformly refers to the end closer to the operator, while "distal end" refers to the end farther from the operator.
[0027] The present invention will now be described in detail with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described herein can be combined with each other.
[0028] The shapes and sizes of the components in the accompanying drawings do not reflect the actual proportions of the product; they are only intended to illustrate the content of the invention.
[0029] This invention provides a thrombus aspiration catheter, primarily addressing the technical problem of traditional thrombus aspiration catheters easily causing "wall biting" and vascular damage during startup due to concentrated instantaneous negative pressure. The catheter includes a catheter body 100, a pressure relief port 200, and a sealing component 300. The proximal end of the catheter body 100 is connected to an aspiration device, and the distal end is provided with the pressure relief port 200. Multiple pressure relief ports 200 are arranged at intervals along the axial and / or circumferential directions to disperse instantaneous negative pressure. The sealing component 300 slides with the catheter body 100, allowing for graded adjustment of the conduction area of the pressure relief ports 200. During operation, the pressure relief port 200 effectively reduces the instantaneous negative pressure at the distal end of the catheter body 100, thereby reducing damage to the blood vessel. After the aspiration device stabilizes, the sealing component 300 seals the pressure relief port 200 to ensure the stability of the aspiration force of the catheter body 100, thus guaranteeing the effectiveness and efficiency of aspiration.
[0030] Example 1
[0031] like Figure 1 , Figure 2As shown, the thrombus aspiration catheter includes a catheter body 100, which adopts a three-layer composite structure. The inner layer is made of medical-grade polytetrafluoroethylene to ensure smooth thrombus delivery; the middle layer is made of braided stainless steel mesh to improve bending resistance; and the outer layer is made of polyether block amide, which has excellent biocompatibility and flexibility. A suction device (not shown in the figure) is connected to the proximal end of the catheter body 100 to obtain suction force. A pressure relief hole 200 is provided through the distal end of the catheter wall, connecting the lumen of the catheter body 100 to the outside, and is used to reduce the instantaneous suction force at the distal suction port of the catheter body 100. Specifically, the pressure relief port 200 can be connected to the external intravascular environment at the initial stage of the aspiration device startup. This can effectively disperse the instantaneous negative pressure at the distal aspiration port of the catheter body 100, thereby effectively dispersing the aspiration stress between the distal aspiration port of the catheter body 100 and the blood vessel, thus reducing the suction force of the distal aspiration port of the catheter body 100 on the blood vessel wall, avoiding the "wall biting" phenomenon, and ensuring the safety of the surgical operation.
[0032] The distal end of the catheter body 100 is also provided with a sealing component 300 for sealing the pressure relief port 200 to control the pressure relief state of the pressure relief port 200 and ensure the stability of the suction force of the catheter body 100. Specifically, the conductive area of the pressure relief port 200 can be adjusted by the sealing component 300, thereby ensuring that the negative pressure intensity of the suction port of the catheter body 100 is insufficient to damage the blood vessel wall when the suction device is initially started, and ensuring the suction efficiency of the thrombus after the suction airflow stabilizes.
[0033] Furthermore, multiple pressure relief holes 200 are arranged at intervals along the axial and / or circumferential direction of the catheter body 100, allowing for flexible adjustment of pressure relief capacity according to different vessel diameters and thrombus types. In this embodiment, the pressure relief holes 200 are arranged in two rows at intervals along the axial direction, with three holes evenly spaced circumferentially in each row. This ensures uniform pressure relief while avoiding a decrease in the structural strength of the catheter body 100 due to excessive openings.
[0034] Furthermore, any two adjacent rows of pressure relief holes 200 are staggered. If two adjacent rows of pressure relief holes face each other, the negative pressure will be released quickly from the facing holes first. This results in an uneven distribution of negative pressure in the circumferential direction of the catheter body 100. That is, the negative pressure in the area facing the holes decays too quickly, while the negative pressure in the non-facing areas is still locally concentrated. This may cause "skewed adsorption" at the distal aspiration port of the catheter body 100 (that is, the part of the distal end of the catheter body 100 facing the pressure relief hole 200 has a strong adsorption force on the blood vessel wall, while the other part of the non-facing pressure relief hole 200 has a weak adsorption force, which causes the distal aspiration port of the catheter body 100 to not fit evenly against the blood vessel wall, and there is still a risk of scratching the blood vessel intima). The staggered arrangement allows adjacent rows of pressure relief holes 200 to form a fully covered negative pressure release channel in the circumferential direction. Taking the axial arrangement of two rows with three holes per row in this embodiment as an example, when adjacent rows of pressure relief holes 200 are staggered, with the circumferential gap between the front row holes and the rear row holes, the pressure relief holes 200 in the distal circumferential direction of the catheter body 100 can uniformly cover a 360° range without any obvious gaps. When the aspiration device is activated, blood or air in the blood vessel can enter the catheter body 100 evenly through the staggered holes, causing the instantaneous negative pressure in the catheter body 100 to decrease synchronously along the circumferential direction. In this way, the suction force at the distal aspiration port is more uniform, avoiding vascular damage caused by "skewed suction".
[0035] Furthermore, the sealing component 300 adopts a sliding sleeve structure, which slides in conjunction with the distal end of the conduit body 100. The degree of sealing of the pressure relief hole 200 is controlled by the sliding of the sliding sleeve along the conduit body 100. A driving component is provided on the sliding sleeve to drive the sliding sleeve to slide along the conduit body 100.
[0036] In this embodiment, a sliding groove 110 is provided axially inside the wall of the catheter body 100. The sliding groove 110 is provided in the outer layer or the inner layer, and a sliding sleeve is arranged in the sliding groove 110. The sliding sleeve slides axially along the sliding groove 110.
[0037] In this embodiment, the driving component is a driving guidewire 400, the distal end of which is fixedly connected to the proximal end of the sliding sleeve, and the proximal end extends along the catheter body 100 to the outside. The operator can pull or push the driving guidewire 400 externally to drive the sliding sleeve to slide along the catheter body 100.
[0038] Furthermore, two guidewires 400 are symmetrically arranged radially along the catheter body 100, which can ensure that the sliding sleeve is subjected to uniform force during sliding and avoid the sliding sleeve from getting stuck or shifting due to unilateral force. At the same time, a sliding channel 120 adapted to the guidewire 400 is opened axially on the wall of the catheter body 100. The guidewire 400 passes through the sliding channel 120. The sliding channel 120 can protect and limit the movement of the guidewire 400, prevent the guidewire 400 from getting stuck with the blood vessel wall or thrombus, and improve the safety of the operation.
[0039] During the procedure, the distal end of the catheter body 100 is inserted into the thrombus location within the blood vessel along the guidewire. At this time, the sheath is in its initial position and does not cover the pressure relief hole 200, which remains open.
[0040] When the aspiration device is started, the instantaneous negative pressure generated in the catheter body 100 in the initial stage is connected to the blood in the blood vessel through the pressure relief hole 200. The negative pressure is dispersed, and the suction force of the distal aspiration port of the catheter body 100 on the blood vessel wall is reduced, thereby avoiding the occurrence of "wall biting".
[0041] After the negative pressure pump is running stably, the guidewire 400 is pushed by the external operating handle, which drives the sliding sleeve to slide along the sliding groove 110 to the distal end until the sliding sleeve completely covers the two rows of pressure relief holes 200. At this time, the negative pressure intensity in the catheter body 100 increases, and efficient aspiration of thrombi begins.
[0042] Example 2
[0043] like Figure 3 As shown, this embodiment provides a blocking component 300 with different settings. In this embodiment, the difference from embodiment 1 is that the blocking component 300 is directly sleeved on the outside of the catheter body 100.
[0044] Example 3
[0045] like Figure 4 As shown, this embodiment provides a pressure relief hole 200 with a different arrangement. The difference between this embodiment and Embodiment 2 is that the pressure relief hole 200 is arranged only along the axial direction of the conduit body 100. In other embodiments, the sealing component 300 can also be arranged in the same way as in Embodiment 1.
[0046] Example 4
[0047] This embodiment provides a pressure relief hole 200 with a different arrangement. In this embodiment, the difference from embodiment 1 is that the pressure relief hole 200 is arranged only along the axial direction of the conduit body 100.
[0048] Example 5
[0049] This embodiment provides a pressure relief hole 200 with a different arrangement. In this embodiment, the difference from embodiment 1 is that the pressure relief hole 200 is arranged only along the circumference of the conduit body 100.
[0050] Example 6
[0051] This embodiment provides a pressure relief hole 200 with a different number of arrangements. The difference between this embodiment and embodiment 1 is that the pressure relief hole 200 is arranged in three rows at intervals along the axial direction.
[0052] Example 7
[0053] This embodiment provides a drive guide wire 400 with a different number of arrangements. The difference between this embodiment and embodiment 1 is that the drive guide wire 400 is provided with one wire.
[0054] In summary, this invention achieves safety in the use of the catheter body by setting a dynamically adjustable pressure relief hole and a sealing component at the distal end of the thrombus aspiration catheter, solves the technical defects of traditional thrombus aspiration catheters, and has a simple structure, is easy to operate, and is suitable for diverse clinical treatment needs, thus having high promotional value.
[0055] It is understood that the above description is merely exemplary and the embodiments of this application do not limit the scope of the application.
[0056] The above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention are within the protection scope of the present invention.
Claims
1. A thrombus aspiration catheter, characterized in that, The device includes a catheter body (100), with a suction device connected to the proximal end of the catheter body (100) and a pressure relief hole (200) provided at the distal end to reduce the instantaneous suction force of the catheter body (100). The distal end of the catheter body (100) is also provided with a sealing component (300) for sealing the pressure relief hole (200) to control the pressure relief state of the pressure relief hole (200) and ensure the stability of the suction force of the catheter body (100).
2. The thrombus aspiration catheter according to claim 1, characterized in that, Multiple pressure relief holes (200) are arranged at intervals along the axial and / or circumferential direction of the conduit body (100).
3. The thrombus aspiration catheter according to claim 1, characterized in that, The sealing component (300) is a sliding sleeve, which slides in conjunction with the distal end of the conduit body (100) to control the degree of sealing of the pressure relief hole (200).
4. The thrombus aspiration catheter according to claim 3, characterized in that, The sliding sleeve is provided with a driving component for driving the sliding sleeve to slide along the guide tube body (100).
5. The thrombus aspiration catheter according to claim 3, characterized in that, The conduit body (100) has a sliding groove (110) arranged inside the conduit wall, and the sliding sleeve is arranged in the sliding groove (110).
6. The thrombus aspiration catheter according to claim 4, characterized in that, The driving component is a driving guidewire (400), the distal end of which is fixedly connected to the proximal end of the sliding sleeve, and the proximal end extends to the outside along the catheter body (100).
7. The thrombus aspiration catheter according to claim 6, characterized in that, Two drive guide wires (400) are arranged symmetrically in the radial direction.
8. The thrombus aspiration catheter according to claim 7, characterized in that, The catheter body (100) has an axially extending sliding channel (120) arranged on its wall, and the drive guidewire (400) is arranged along the sliding channel (120).
9. The thrombus aspiration catheter according to claim 2, characterized in that, The pressure relief holes (200) are arranged in multiple rows at intervals along the axial direction, and each row of pressure relief holes (200) is arranged in multiple rows at intervals along the circumferential direction.
10. The thrombus aspiration catheter according to claim 9, characterized in that, The pressure relief holes (200) in any two adjacent rows are staggered.