Disposable aqueous humor specimen collection device

Abstract

The present invention discloses a disposable aqueous humor specimen collection device, which relates to the technical field of intraocular fluid detection. It includes a cylinder assembly, a needle piston assembly and a spring assembly arranged in the cylinder assembly. Among them, the needle piston assembly includes a telescopic piston, a telescopic sleeve, a puncture needle and a puncture needle body. The outer wall of the telescopic piston abuts against the inner wall of the cylinder assembly. The telescopic sleeve is slidably arranged inside the telescopic piston. The puncture needle body is arranged inside the telescopic sleeve. A puncture needle is arranged at one end of the puncture needle body. A spring assembly is arranged on the outer wall of the puncture needle body. The aqueous humor specimen collection device in the present invention can effectively avoid intraoperative secondary injuries caused by the movement of the patient's eyeball during the operation, and at the same time avoid the loss of the amount of intraocular fluid specimen collected by the syringe, accurately control the volume of the sampled intraocular fluid, the operation process is convenient and fast, and can significantly reduce the pain of the patient.

Description

Technical Field

[0001] The present invention relates to the technical field of intraocular fluid detection, and particularly to a disposable aqueous humor specimen collection device. Background Art

[0002] The internal tissues of the eyeball have established a unique immune microenvironment different from other tissues and organs through the blood-eye barrier. Some intraocular diseases can be confined to this microenvironment, thus lacking extraocular manifestations; although some patients have systemic manifestations and positive results in auxiliary examinations throughout the body, it is still difficult to judge the relationship between ocular manifestations and systemic manifestations and results based on this. Intraocular fluid detection can directly reflect various information in the intraocular microenvironment, and is of great value for the diagnosis and differential diagnosis of various infectious and neoplastic diseases. Some of the detection indicators can also be used for disease follow-up, quantitatively reflecting the disease changes in real time, and can be used for prognosis judgment. Aqueous humor is the most common specimen type for intraocular fluid detection because it is relatively convenient and safe to obtain. When collecting aqueous humor in an ophthalmology examination room, an insulin syringe (29G) or a 1 ml syringe (26G) is mostly used to penetrate the anterior chamber parallel to the iris 0.5 mm behind the corneal limbus at a convenient operation position, and the plunger is slowly pulled gently to aspirate 0.1 - 0.2 ml of aqueous humor. Because only one hand can be operated under a slit lamp microscope and the field of view adjustment is difficult, it is both difficult and unsafe to obtain a large amount of aqueous humor specimens.

[0003] Since topical anesthesia is mostly used when performing anterior chamber puncture to collect aqueous humor in an ophthalmology examination room and the operation is carried out with one hand under a slit lamp microscope, patients often have involuntary eye movements during the operation due to nervousness, resulting in local eye injuries during the puncture process, such as corneal epithelial scratches, conjunctival lacerations and bleeding. Serious adverse consequences will also occur for beginners and doctors who are not proficient in the operation during anterior chamber puncture and fluid aspiration, such as injuring the lens and causing cataract with decreased vision; injuring the iris and causing anterior chamber hemorrhage, etc. Summary of the Invention

[0004] The purpose of the present invention is to provide a disposable aqueous humor specimen collection device to solve the above technical problems.

[0005] The technical solution adopted by the present invention is as follows:

[0006] A disposable aqueous humor specimen collection device includes a cylinder assembly, a needle piston assembly and a spring assembly arranged in the cylinder assembly. Among them, the needle piston assembly includes a telescopic piston, a telescopic sleeve, a puncture needle head and a puncture needle body. The outer wall of the telescopic piston abuts against the inner wall of the cylinder assembly. The telescopic sleeve is slidably arranged inside the telescopic piston. The puncture needle body is arranged inside the telescopic sleeve. One end of the puncture needle body is provided with the puncture needle head, and the spring assembly is arranged on the outer wall of the puncture needle body.

[0007] Preferably, the cylinder assembly includes a syringe barrel, a syringe barrel cap, and a suction bladder. The telescopic piston is disposed inside the syringe barrel and abuts against the inner wall of the syringe barrel. One end of the telescopic piston extends out of one end of the syringe barrel. The syringe barrel cap is movably disposed at the other end of the syringe barrel, and the suction bladder is disposed on the syringe barrel cap.

[0008] As a further preference, a connecting flange is further included. The connecting flange is disposed inside the syringe barrel and is located at the other end of the telescopic piston.

[0009] As a further preference, the connecting flange divides the interior of the syringe barrel into an installation chamber and a collection chamber. Among them, the needle piston assembly is disposed inside the installation chamber.

[0010] As a further preference, the spring assembly includes a first spring. The other end of the puncture needle body passes through the connecting flange and is located inside the collection chamber. One end of the first spring is sleeved on the other end of the puncture needle body, and the other end of the first spring abuts against the syringe barrel cap.

[0011] As a further preference, a second spring is further included. The second spring is sleeved on one end of the puncture needle body, and one end of the second spring abuts against the telescopic sleeve.

[0012] As a further preference, the stiffness of the first spring is greater than the stiffness of the second spring.

[0013] As a further preference, the puncture needle head communicates with the puncture needle body, the puncture needle body communicates with the collection chamber, and the collection chamber communicates with the suction bladder.

[0014] Preferably, the puncture needle body and the puncture needle head are coaxially arranged.

[0015] As a further preference, a protective needle sleeve is further included. The protective needle sleeve is disposed at one end of the syringe barrel and is detachably disposed on the outer edge of one end of the telescopic piston.

[0016] The above technical solution has the following advantages or beneficial effects:

[0017] In the present invention, by collecting a very small amount of intraocular fluid specimens, a variety of important intraocular microenvironment information can be provided simultaneously, providing important qualitative and quantitative bases for the diagnosis, monitoring, and follow-up of various intraocular diseases. By using this instrument, intraoperative secondary injuries caused by the movement of the patient's eyeball during the operation can be effectively avoided, and at the same time, the loss of the amount of intraocular fluid specimens collected by the syringe is avoided, the volume of the sampled intraocular fluid is accurately controlled, the operation process is convenient and fast, and the patient's pain can be significantly reduced. Description of the Drawings

[0018] Figure 1 It is a schematic structural diagram of the initial state of the aqueous humor specimen collection device in the present invention;

[0019] Figure 2 It is a schematic structural diagram of the puncture state of the aqueous humor specimen collection device in the present invention;

[0020] Figure 3 It is a schematic structural diagram of the compression state of the aqueous humor specimen collection device in the present invention.

[0021] In the figure: 1, puncture needle; 2, second spring; 3, puncture needle body; 4, telescopic sleeve; 5, telescopic piston; 6, connecting flange; 7, syringe barrel; 8, first spring; 9, syringe barrel cap; 10, suction sac; 11, protective needle sleeve. Specific embodiments

[0022] Next, the technical solutions of the present invention will be clearly and completely described in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of them. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without making creative efforts shall fall within the protection scope of the present invention.

[0023] In the description of the present invention, it should be noted that when terms such as "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. appear, the orientation or positional relationship indicated is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention. In addition, when terms such as "first", "second", "third" appear, they are only for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0024] In the description of the present invention, it should be noted that unless otherwise clearly specified and limited, when terms such as "installation", "connection", "connection" are used, they should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0025] Figure 1 It is a schematic structural diagram of the initial state of the aqueous humor specimen collection device in the present invention; Figure 2 It is a schematic structural diagram of the puncture state of the aqueous humor specimen collection device in the present invention; Figure 3It is a schematic structural diagram of the compressed state of the aqueous humor specimen collection device in the present invention. Refer to Figures 1 - 3 As shown, a preferred embodiment is shown. The disposable aqueous humor specimen collection device shown includes a cylinder assembly, a needle piston assembly and a spring assembly provided in the cylinder assembly. Among them, the needle piston assembly includes a telescopic piston 5, a telescopic sleeve 4, a puncture needle 1 and a puncture needle body 3. The outer wall of the telescopic piston 5 abuts against the inner wall of the cylinder assembly. A telescopic sleeve 4 is slidably provided inside the telescopic piston 5. A puncture needle body 3 is provided inside the telescopic sleeve 4. A puncture needle 1 is provided at one end of the puncture needle body 3. A spring assembly is provided on the outer wall of the puncture needle body 3. In this embodiment, as Figure 1 shown, the needle piston assembly is movably provided in the cylinder assembly. Among them, the telescopic sleeve 4 can slide relative to the telescopic piston 5. The outer wall of the telescopic sleeve 4 abuts against the inner wall of the telescopic piston 5. The puncture needle body 3 is movably provided in the telescopic sleeve 4. The provided spring assembly facilitates accurately controlling the puncture needle 1 to enter the aqueous humor extraction site of the eyeball and also facilitates the reset of the puncture needle 1.

[0026] Further, as a preferred implementation manner, the cylinder assembly includes a syringe barrel 7, a syringe barrel cap 9 and a suction sac 10. The telescopic piston 5 is provided in the syringe barrel 7 and abuts against the inner wall of the syringe barrel 7. And one end of the telescopic piston 5 extends out of one end of the syringe barrel 7. The syringe barrel cap 9 is movably provided at the other end of the syringe barrel 7. The suction sac 10 is provided on the syringe barrel cap 9. In this embodiment, as Figure 1 shown, the syringe barrel cap 9 can slide into the syringe barrel 7. When in use, the syringe barrel cap 9 enters the syringe barrel 7 and squeezes the spring assembly, so that the spring assembly controls the puncture needle 1 to enter the aqueous humor extraction site of the eyeball. Squeezing the suction sac 10 can be used to aspirate aqueous humor. As Figure 1 shown, a step surface is provided on the inner wall of the syringe barrel 7, and a step surface is also provided on the outer wall of the telescopic piston 5. The telescopic piston 5 and the syringe barrel 7 are matched through the step surface to limit the position of the telescopic piston 5. The telescopic piston 5 and the telescopic sleeve 4 are also matched through the step surface to realize the limit of the telescopic sleeve 4.

[0027] Further, as a preferred implementation manner, it further includes a connecting flange. A connecting flange is provided in the syringe barrel 7 and is located at the other end of the telescopic piston 5.

[0028] Further, as a preferred implementation manner, the connecting flange divides the interior of the syringe barrel 7 into an installation chamber and a collection chamber. Among them, the needle piston assembly is provided in the installation chamber. In this embodiment, the connecting flange is movably provided in the syringe barrel 7. The side of the connecting flange close to the suction sac 10 is the collection chamber, and the side far from the suction sac 10 is the installation chamber.

[0029] Further, as a preferred embodiment, the spring assembly includes a first spring 8, the other end of the puncture needle body 3 passes through the connecting flange and is located in the collection chamber, one end of the first spring 8 is sleeved on the other end of the puncture needle body 3, and the other end of the first spring 8 is against the syringe cover 9. In this embodiment, the first spring 8 is located in the collection chamber, and when the syringe cover 9 enters the syringe 7, the first spring 8 is compressed, thereby squeezing the connecting flange and the puncture needle body 3.

[0030] Furthermore, as a preferred embodiment, it also includes a second spring 2 , which is sleeved on one end of the puncture needle body 3 , and one end of the second spring 2 is against the telescopic sleeve 4 .

[0031] Further, as a preferred embodiment, the stiffness of the first spring 8 is greater than the stiffness of the second spring 2. Further, as a preferred embodiment, the puncture needle 1 is connected to the puncture needle body 3, the puncture needle body 3 is connected to the collection chamber, and the collection chamber is connected to the suction capsule 10. In this embodiment, when the suction capsule 10 is squeezed, the aqueous humor of the eyeball aqueous humor collection site will pass through the puncture needle 1 into the puncture needle body 3, and into the collection chamber, and finally into the suction capsule 10.

[0032] Furthermore, as a preferred embodiment, the puncture needle body 3 and the puncture needle head 1 are coaxially arranged.

[0033] Further, as a preferred embodiment, a protective needle sleeve 11 is provided at one end of the syringe 7 , and the protective needle sleeve 11 is detachably provided on the outer edge of one end of the telescopic piston 5 .

[0034] In this embodiment, when in use, first remove the protective needle sleeve 11, pinch the suction capsule 10, and remove some air (A original state). Then press toward the eyeball to take the aqueous humor. At this time, the telescopic sleeve 4 is pressed against the eyeball. Due to the different stiffness between the first spring 8 and the second spring 2, the first spring 8 can press the needle piston assembly to move together. Therefore, when squeezing the syringe cover 9, the first spring 8 will squeeze the connecting flange, thereby driving the puncture needle body 3 to move. At this time, the second spring 2 is compressed until the step surface on the outer wall of the puncture needle body 3 is against the step surface on the inner wall of the telescopic sleeve 4. At this time, the puncture needle 1 just penetrates the eye chamber 2.5mm. Continue to press down, the syringe 7 assembly will compress the spring 8 to the preset position, and press down while slightly releasing the knob so that the telescopic piston 5 retreats and the air pressed out enters the suction capsule 10 (Figure C compressed state). Then, the spring reset and suction stage is entered. Slowly release the pinch and the downward pressure. After that, the first spring 8 first pushes back the syringe cover 9, and the volume of the syringe 7 cavity increases and the suction capsule 10 expands to suck out the eye fluid. The volume is determined by the set relative movement distance of the telescopic piston 5 and the syringe 7. Then, the hand pressure is completely removed, and the puncture needle 1 is quickly withdrawn from the eye by the second spring 2. The suction capsule 10 is removed, and the sampled eye fluid can be drawn out from the hole of the syringe cover 9 to complete the surgical operation.

[0035] The above are only the preferred embodiments of the present invention, and thus do not limit the implementation manners and protection scope of the present invention. For those skilled in the art, it should be realized that all the equivalent substitutions and obvious changes made by using the description and illustrations of the present invention should be included within the protection scope of the present invention.

Claims

1. Disposable aqueous humor specimen collection device, Characterized in that, It includes a cylinder assembly, a needle piston assembly and a spring assembly arranged in the cylinder assembly. Among them, the needle piston assembly includes a telescopic piston, a telescopic sleeve, a puncture needle head and a puncture needle body. The outer wall of the telescopic piston abuts against the inner wall of the cylinder assembly. The telescopic sleeve is slidably arranged inside the telescopic piston. The puncture needle body is arranged inside the telescopic sleeve. One end of the puncture needle body is provided with the puncture needle head. The spring assembly is arranged on the outer wall of the puncture needle body; The cylinder assembly includes a syringe barrel, a syringe barrel cap and a suction bladder. The telescopic piston is arranged in the syringe barrel and abuts against the inner wall of the syringe barrel. One end of the telescopic piston extends out of one end of the syringe barrel. The syringe barrel cap is movably arranged at the other end of the syringe barrel. The suction bladder is arranged on the syringe barrel cap; It also includes a connecting flange. The connecting flange is arranged inside the syringe barrel and is located at the other end of the telescopic piston; The connecting flange divides the inside of the syringe barrel into an installation chamber and a collection chamber. Among them, the needle piston assembly is arranged in the installation chamber; The spring assembly includes a first spring. The other end of the puncture needle body passes through the connecting flange and is located in the collection chamber. One end of the first spring is sleeved on the other end of the puncture needle body. The other end of the first spring abuts against the syringe barrel cap; It also includes a second spring. The second spring is sleeved on one end of the puncture needle body. One end of the second spring abuts against the telescopic sleeve; The stiffness of the first spring is greater than that of the second spring; The puncture needle head communicates with the puncture needle body. The puncture needle body communicates with the collection chamber. The collection chamber communicates with the suction bladder.

2. The aqueous humor specimen collection device according to claim 1, Characterized in that, The puncture needle body and the puncture needle head are coaxially arranged.

3. The aqueous humor specimen collection device according to claim 1, Characterized in that, It also includes a protective needle sleeve. The protective needle sleeve is arranged at one end of the syringe barrel and is detachably arranged on the outer edge of one end of the telescopic piston.

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