A rotating multi-sample detection kit for Raman spectroscopy

Abstract

The present invention relates to a rotary multi-sample detection kit for Raman spectroscopy, comprising: a sampling bottle; a stand base; a turntable arranged on the stand base and rotatable in a horizontal plane: the turntable is provided with a plurality of sockets that penetrate up and down and are used to place inverted sampling bottles around its rotation center; a stand vertical rod arranged on the stand base and located beside the turntable: a Raman spectrometer that can move up and down and is located below the turntable is also provided on the vertical rod, and the direction of the probe of the Raman spectrometer intersects with the circle surrounded by all the sockets. Compared with the prior art, the present invention can realize direct and rapid on-site detection of multiple samples, etc.

Description

Technical Field

[0001] The invention belongs to the technical field of detection equipment and relates to a rotary multi-sample detection kit for Raman spectroscopy. Background Art

[0002] It can provide rich structural information inside the molecules of a substance and is also regarded as a "molecular fingerprint technology", which can be mainly used for qualitative identification of substances.

[0003] Raman spectrometers identify substances by stimulating and collecting Raman spectra of substances. The instrument has the advantages of simple structure, easy operation, fast, efficient and accurate measurement, low wavenumber measurement, etc. Raman spectrometers are simple to prepare samples and do not damage samples. Therefore, Raman spectrometers are widely used in scientific research institutes, physical and chemical laboratories of colleges and universities, biological and medical fields, etc. to study the determination and confirmation of material composition; they can also be used in criminal investigation and jewelry industry for drug detection and gem identification.

[0004] With the rapid development of spectroscopy technology, various portable and handheld Raman spectrometers have been introduced. Among them, portable Raman spectrometers are widely used in rapid detection of chemicals because of their flexible use, simple operation and easy portability.

[0005] The probe of an ordinary portable Raman spectrometer can directly penetrate transparent and translucent packaging for detection, but for samples in different packaging such as dark glass bottles, colored plastic bottles and paper bags, ordinary Raman cannot directly penetrate for detection, and the samples in such packaging need to be poured into transparent packaging before the Raman test, such as transparent cuvettes commonly used in liquid Raman tests, transparent sealed bags used in solid Raman tests, etc. Their use can better obtain the spectral signal of the substance to be tested, but the operation process is time-consuming and cumbersome, and for some samples with irritating odors and high toxicity, it is very easy to cause sample leakage such as odor diffusion and toxic gas spread during the transfer of samples to transparent packaging. The occurrence of these phenomena will not only endanger the life and health of on-site personnel, but also seriously damage the laboratory working environment and production safety. In addition, in the actual Raman test process, ordinary portable Raman spectrometers often need to manually change the test samples in advance and adjust the samples to the focal area of ​​the Raman probe. When the number of samples is large, the operation is more time-consuming, and the difference in the placement area of ​​each sample may also lead to deviations in the spectral test results. Therefore, how to directly perform effective and rapid Raman detection on multiple packaged samples is of great significance.

[0006] Chinese patent CN113970539A provides a Raman spectroscopy method for rapid detection of substances in packaging containers. Its principle is a spatial offset Raman detection method based on the sample photon transfer model, which can be applied to Raman detection of samples in containers such as glass and plastic. However, this method requires at least two positions of the sample in the package to be collected, which takes a long time; and it is necessary to construct a photon transfer model for a single sample, which is a complicated process and cannot meet the needs of rapid on-site detection of samples. Summary of the invention

[0007] The purpose of the present invention is to provide a rotary multi-sample detection kit for Raman spectroscopy to meet the demand for rapid on-site detection of samples.

[0008] The purpose of the present invention can be achieved by the following technical solutions:

[0009] A rotating multi-sample detection kit for Raman spectroscopy, comprising:

[0010] Sampling bottles;

[0011] Bench base;

[0012] A turntable is arranged on the stand base and can rotate in a horizontal plane: the turntable is provided with a plurality of holes which are passed through from top to bottom and are used to place inverted sampling bottles around its rotation center;

[0013] A stand vertical rod is arranged on the stand base and located beside the turntable: a Raman spectrometer which can move up and down and is located below the turntable is also arranged on the vertical rod, and the direction of the probe of the Raman spectrometer intersects with the circle surrounded by all the jacks.

[0014] Furthermore, a barcode area is provided on the outer surface of the sampling bottle, and a barcode window facing the barcode area on the sampling bottle is also provided on the outer surface of the turntable.

[0015] Furthermore, a barcode scanning probe facing the barcode window is also provided on the vertical rod of the stand.

[0016] Furthermore, an adjustment cross bar which can move up and down is provided on the vertical rod of the stand, and the Raman spectrometer is fixedly arranged on the adjustment cross bar.

[0017] Furthermore, a limiting cross bar is provided on the vertical bar of the stand, and a limiting through hole is provided on the limiting cross bar. The Raman spectrometer passes through the limiting through hole, and the limiting through hole limits the Raman spectrometer to move only in the up and down direction.

[0018] Furthermore, a positioning rod is provided on the stand base, and the turntable is rotatably arranged on the positioning rod.

[0019] Furthermore, the positioning rod is also provided with a turntable driving structure for driving the turntable to rotate on the positioning rod.

[0020] Furthermore, the sampling bottle comprises a bottle body, an inner cover arranged at the bottle mouth of the bottle body, and an outer cover covering the inner cover, and the inner cover is provided with a sampling channel connected to the internal cavity of the bottle body.

[0021] Furthermore, the sampling channel is in the shape of an inverted frustum.

[0022] Furthermore, the through hole on the inner cover is sealed with a light-transmitting transparent film.

[0023] Compared with the prior art, the present invention can realize direct and rapid on-site detection of multiple samples through matching sampling bottles and turntables. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a structural schematic diagram of the present invention;

[0025] Figure 2 It is a top view schematic diagram of the turntable part of the present invention;

[0026] Figure 3 is a schematic diagram of a sampling bottle of the present invention;

[0027] Figure 4 It is a structural schematic diagram of the jack part of the present invention;

[0028] Description of the markings in the figure:

[0029] 1-bottle body, 2-inner cover, 3-outer cover, 4-barcode area, 5-circular hole structure, 6-sampling channel, 7-stand base, 8-positioning rod, 9-turntable driving structure, 10-turntable, 11-barcode window, 12-stand vertical rod, 13-limiting cross bar, 14-adjusting cross bar, 15-positioning knob, 16-barcode scanning probe, 17-Raman spectrometer. DETAILED DESCRIPTION

[0030] The present invention is described in detail below in conjunction with the accompanying drawings and specific embodiments. This embodiment is implemented based on the technical solution of the present invention, and provides a detailed implementation method and specific operation process, but the protection scope of the present invention is not limited to the following embodiments.

[0031] In the following implementation manners or examples, unless otherwise specified, functional components or structures are conventional components or conventional structures used in the art to achieve corresponding functions.

[0032] In order to realize direct and rapid on-site detection of multiple samples, the present invention provides a rotating multi-sample detection kit for Raman spectroscopy, the structure of which is shown in Figures 1 to 4 As shown, including:

[0033] Sampling bottles;

[0034] Stand base 7;

[0035] A turntable 10 is arranged on the stand base 7 and can rotate in a horizontal plane. The turntable 10 is also provided with a plurality of holes extending vertically and used for placing inverted sampling bottles around its rotation center.

[0036] A stand vertical rod 12 is disposed on the stand base 7 and is located next to the turntable 10. A Raman spectrometer 17 is also disposed on the vertical rod and is movable up and down and is located below the turntable 10. The probe of the Raman spectrometer 17 is oriented to intersect the circle formed by all the jacks.

[0037] In some specific embodiments, a barcode area 4 is provided on the outer surface of the sampling bottle, and a barcode window 11 facing the barcode area 4 on the sampling bottle is also provided on the outer surface of the turntable 10 .

[0038] Furthermore, a barcode scanning probe 16 facing the barcode window 11 is also provided on the stand vertical rod 12 .

[0039] In some specific implementations, the stand vertical rod 12 is provided with an adjustment cross rod 14 that can move up and down along the cross rod, and the Raman spectrometer 17 is fixedly arranged on the adjustment cross rod 14 .

[0040] Furthermore, a limiting cross bar 13 is provided on the stand vertical bar 12, and a limiting through hole is provided on the limiting cross bar 13. The Raman spectrometer 17 passes through the limiting through hole, and the Raman spectrometer 17 is limited by the limiting through hole to move only in the up and down direction.

[0041] In some specific implementations, a positioning rod 8 is provided on the stand base 7 , and the turntable 10 is rotatably disposed on the positioning rod 8 .

[0042] Furthermore, the positioning rod 8 is also provided with a turntable driving structure 9 for driving the turntable 10 to rotate on the positioning rod 8 .

[0043] In some specific embodiments, the sampling bottle includes a bottle body 1, an inner cover 2 arranged at the bottle mouth of the bottle body 1, and an outer cover 3 covering the inner cover 2, and the inner cover 2 is provided with a sampling channel 6 connected to the internal cavity of the bottle body 1.

[0044] Furthermore, the sampling channel 6 is in the shape of an inverted frustum.

[0045] Furthermore, the through hole on the inner cover 2 is sealed with a light-transmitting transparent film.

[0046] The above embodiments may be implemented individually or in any combination of two or more.

[0047] The above implementation is described in more detail below in conjunction with specific examples.

[0048] Embodiment 1:

[0049] In order to realize direct and rapid on-site detection of multiple samples, the present invention provides a rotating multi-sample detection kit for Raman spectroscopy, the structure of which is shown in Figures 1 to 4 As shown, including:

[0050] Sampling bottles;

[0051] Stand base 7;

[0052] A turntable 10 is arranged on the stand base 7 and can rotate in a horizontal plane: the turntable 10 is also provided with n holes that penetrate up and down and are used to place inverted sampling bottles around its rotation center, and n is a positive integer;

[0053] A stand vertical rod 12 is disposed on the stand base 7 and is located next to the turntable 10. A Raman spectrometer 17 is also disposed on the vertical rod and is movable up and down and is located below the turntable 10. The direction of the probe of the Raman spectrometer 17 intersects the circle surrounded by all the jacks.

[0054] The outer surface of the sampling bottle is provided with a barcode area 4, and the outer surface of the turntable 10 is also provided with a barcode window 11 facing the barcode area 4 on the sampling bottle. A barcode scanning probe 16 facing the barcode window 11 is also provided on the stand vertical rod 12.

[0055] The stand vertical rod 12 is provided with an adjustment crossbar 14 that can move up and down along it, and the Raman spectrometer 17 is fixedly arranged on the adjustment crossbar 14. The stand vertical rod 12 is also provided with a limit crossbar 13, and a limit through hole is provided on the limit crossbar 13. The Raman spectrometer 17 passes through the limit through hole, and the limit through hole limits the Raman spectrometer 17 to move only in the up and down direction. A positioning rod 8 is provided on the stand base 7, and a turntable 10 is rotatably arranged on the positioning rod 8. The positioning rod 8 is also provided with a turntable driving structure 9 that drives the turntable 10 to rotate on the positioning rod 8. The sampling bottle includes a bottle body 1, an inner cover 2 arranged at the bottle mouth position of the bottle body 1, and an outer cover 3 covering the inner cover 2. The bottle body 1 and the outer cover 3 are made of light-proof materials. The inner cover 2 is provided with a sampling channel 6 that connects the internal cavity of the bottle body 1, which is in an inverted truncated cone shape, that is, a truncated cone shape with "large inside and small outside". The through hole on the inner cover 2 is also sealed with a layer of light-transmitting transparent film.

[0056] The multi-sample detection kit of this embodiment adopts the following steps:

[0057] (1) Align the probe of the Raman spectrometer 17 and the barcode scanning probe 16 with the nth jack on the turntable 10 and the nth barcode window 11 .

[0058] (2) Open the outer cover 3 of the sampling bottle containing the sample.

[0059] (3) Invert the bottle body 1 and shake the sample in the bottle to gather in the sampling channel 6 of the inner cover 2 with an inverted truncated cone structure (suitable for the case where the amount of sample in the bottle is small).

[0060] (4) The bottleneck of the inverted sample bottle is passed through the insertion hole on the turntable 10 and placed firmly on the turntable 10 , with the barcode area 4D of the bottle body 1 facing outwardly toward the barcode window 11 on the turntable 10 .

[0061] (5) Insert all n-1 sample bottles upside down in sequence into the remaining insertion holes of the turntable 10.

[0062] (6) Rotate the turntable 10 clockwise or counterclockwise to align the n-1th or first barcode window 11 with the barcode scanning probe 16, and align the n-1th or first jack with the probe of the Raman spectrometer 17.

[0063] (7) Complete the barcode scanning;

[0064] (8) Turn the adjustment knob 15 to move the probe of the Raman spectrometer 17 upward so that the top of the probe is seamlessly attached to the transparent polymer film at the circular hole structure 5 on the inner cover 2 of the sampling bottle to complete the Raman spectrum acquisition.

[0065] (9) Turn the adjustment knob 15 to move the probe of the Raman spectrometer 17 downward so that the top of the probe is separated from the transparent polymer film of the circular hole structure 5 on the inner cover 2 of the sampling bottle.

[0066] (10) Repeat steps (6) and (9) to measure all the samples on the turntable 10 and then switch to another batch.

[0067] (11) After the test is completed, remove the sample bottle and place it upright, cover it with the outer cover 3 and tighten it for subsequent testing and identification.

[0068] The above description of the embodiments is to facilitate the understanding and use of the invention by those skilled in the art. It is obvious that those skilled in the art can easily make various modifications to these embodiments and apply the general principles described herein to other embodiments without creative work. Therefore, the present invention is not limited to the above embodiments, and improvements and modifications made by those skilled in the art based on the disclosure of the present invention without departing from the scope of the present invention should be within the scope of protection of the present invention.

Claims

1. A rotating multi-sample detection kit for Raman spectroscopy, characterized in that: include: Sampling bottles; Bench base; A turntable is arranged on the stand base and can rotate in a horizontal plane: the turntable is provided with a plurality of holes which are passed through from top to bottom and are used to place inverted sampling bottles around its rotation center; A stand vertical rod is arranged on the stand base and located beside the turntable: a Raman spectrometer is also arranged on the vertical rod and can move up and down and is located below the turntable, and the direction of the probe of the Raman spectrometer intersects the circle surrounded by all the jacks; A barcode area is provided on the outer surface of the sampling bottle, and a barcode window facing the barcode area on the sampling bottle is also provided on the outer surface of the turntable; The vertical rod of the stand is also provided with a barcode scanning probe facing the barcode window; The sampling bottle comprises a bottle body, an inner cover arranged at the bottle mouth of the bottle body, and an outer cover covering the inner cover, wherein the inner cover is provided with a sampling channel communicating with the inner cavity of the bottle body; The sampling channel is in the shape of an inverted frustum; The through hole on the inner cover is also sealed with a light-transmitting transparent film; The vertical rod of the stand is provided with an adjustment crossbar which can move up and down along the vertical rod, and the Raman spectrometer is fixedly arranged on the adjustment crossbar; The vertical rod of the stand is also provided with a limit cross bar, and a limit through hole is provided on the limit cross bar. The Raman spectrometer passes through the limit through hole, and the limit through hole limits the Raman spectrometer to move only in the up and down direction; A positioning rod is provided on the stand base, and the turntable is rotatably arranged on the positioning rod; The positioning rod is also provided with a turntable driving structure for driving the turntable to rotate on the positioning rod.

2. The rotary multi-sample detection kit for Raman spectroscopy according to claim 1, characterized in that: The working process of the rotary multi-sample detection kit is as follows: (1) Align the Raman spectrometer probe and barcode scanner probe with the nth jack and the nth barcode window on the turntable; (2) Open the outer cover of the sampling bottle containing the sample; (3) Turn the bottle upside down and shake the sample in the bottle to gather in the sampling channel of the inner cover with an inverted truncated cone structure; (4) Place the neck of the inverted sample bottle through the socket on the turntable and place it firmly on the turntable, with the barcode area on the bottle body facing outward and aligned with the barcode window on the turntable; (5) Insert all n-1 sample bottles upside down into the remaining sockets of the turntable in sequence; (6) Turn the dial clockwise or counterclockwise to align the n-1th or 1st barcode window with the barcode scanning probe, and align the n-1th or 1st jack with the probe of the Raman spectrometer; (7) Complete the barcode scanning; (8) Turn the adjustment knob to move the probe of the Raman spectrometer upward so that the top of the probe is seamlessly attached to the transparent polymer film at the circular hole structure on the inner cover of the sampling bottle to complete the Raman spectrum acquisition; (9) Turn the adjustment knob to move the probe of the Raman spectrometer downward so that its top is separated from the transparent polymer film with a circular hole structure on the inner cover of the sampling bottle; (10) Repeat steps (6) to (9) until all samples on the turntable are measured and then switch to another batch; (11) After the test is completed, remove the sample bottle and place it upright, cover it with the outer cover and tighten it for subsequent testing and identification.

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