Left ventricular parameter determination method, device and ultrasonic imaging equipment

Abstract

The present invention provides a method, device, and ultrasonic imaging device for determining left ventricular parameters. The method comprises: collecting two-dimensional ultrasonic cardiac data of a target subject over a continuous period of time, the continuous period being greater than one cardiac cycle, the two-dimensional ultrasonic cardiac data comprising multiple frames of two-dimensional ultrasonic cardiac images; determining multiple target frame images from the multiple frames of two-dimensional ultrasonic cardiac images, the target frame images comprising multiple frames of end-diastolic images corresponding to the end-diastolic phase and multiple frames of end-systolic images corresponding to the end-systolic phase; performing image segmentation on the target frame images to determine the left ventricular contour of the target frame images; determining the apex point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve in the left ventricular contour; and determining left ventricular parameters based on the left ventricular contour, the apex point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve. The present invention balances the efficiency and accuracy of left ventricular measurement.

Description

Technical Field

[0001] The present invention relates to the technical field of left ventricular ultrasonic measurement, and in particular to a left ventricular parameter determination method, device and ultrasonic imaging equipment. Background Art

[0002] Hemodynamic measurement of cardiac function is crucial for early diagnosis, treatment decision-making, efficacy evaluation, and prognostication in patients with heart disease. Measurement of cardiac function and left ventricular systolic function are essential components of echocardiography. While new ultrasound technologies, such as tissue Doppler and three-dimensional echocardiography, have made cardiac function measurement more quantitative and accurate, two-dimensional echocardiography remains the primary method for quantitative measurement of cardiac chambers and assessment of left ventricular systolic function.

[0003] Left ventricular (LV) measurement can be performed in three ways: manual, semi-automatic, and fully automatic. The manual method involves the physician manually drawing the LV outline using an input device such as a trackball or touchscreen. The semi-automatic method involves the physician selecting three key points and automatically generating the LV outline. The fully automatic method involves the physician automatically generating the LV outline with a single trigger. The manual method is the most time-consuming, while the semi-automatic method is faster but also involves more complex steps. The fully automatic method generates the outline with a single click, saving time but offering lower accuracy.

[0004] Therefore, there is an urgent need to propose a left ventricular parameter determination method, device and ultrasonic imaging equipment to solve the technical problem that the existing technology cannot take into account both measurement efficiency and measurement accuracy. Summary of the Invention

[0005] In view of this, it is necessary to provide a left ventricular parameter determination method, device and ultrasonic imaging equipment to solve the technical problem existing in the prior art that it is impossible to take into account both measurement efficiency and measurement accuracy.

[0006] In one aspect, the present invention provides a method for determining left ventricular parameters, comprising:

[0007] Acquiring two-dimensional ultrasound cardiac data of a target object within a continuous time period, wherein the continuous time period is greater than one cardiac cycle, and the two-dimensional ultrasound cardiac data includes multiple frames of two-dimensional ultrasound cardiac images;

[0008] Determining a plurality of target frame images among the plurality of two-dimensional ultrasound cardiac image frames, wherein the target frame images include a plurality of end-diastolic image frames corresponding to the end-diastole and a plurality of end-systolic image frames corresponding to the end-systole;

[0009] performing image segmentation on the target frame image to determine the left ventricular contour of the target frame image;

[0010] Determining the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve in the left ventricular contour;

[0011] Left ventricular parameters are determined according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve.

[0012] In some possible implementations, performing image segmentation on the target frame image to determine the left ventricular contour of the target frame image includes:

[0013] Performing image segmentation on the target frame image to obtain an initial left ventricular contour;

[0014] Preprocessing the initial left ventricular contour to obtain a left ventricular contour to be confirmed;

[0015] determining whether the to-be-confirmed left ventricular contour includes multiple connected regions; if the to-be-confirmed left ventricular contour includes only one connected region, the connected region is the target connected region; if the to-be-confirmed left ventricular contour includes at least two connected regions, the connected region with the largest area is the target connected region;

[0016] The contour of the target connected area is extracted to obtain the left ventricle contour.

[0017] In some possible implementations, determining the apex position point in the left ventricular contour includes:

[0018] constructing a reference coordinate system based on the left ventricular contour, and determining at least one first candidate point having the smallest ordinate value in the left ventricular contour in the reference coordinate system;

[0019] The ordinate of the at least one first candidate point is used as the ordinate of the cardiac apex position point, and the average value of the abscissas of the at least one first candidate point is used as the abscissa of the cardiac apex position point.

[0020] In some possible implementations, determining at least one first candidate point having the smallest ordinate value in the left ventricular contour in the reference coordinate system includes:

[0021] determining a minimum circumscribed rectangle of the left ventricular contour, and determining a plurality of intersection points between the minimum circumscribed rectangle and the left ventricular contour;

[0022] At least one first candidate point having the smallest ordinate value among the plurality of intersection points in the reference coordinate system is determined.

[0023] In some possible implementations, after the ordinate of the at least one first candidate point is used as the ordinate of the cardiac apex position point and the average of the abscissas of the at least one first candidate point is used as the abscissa of the cardiac apex position point, the method further includes:

[0024] Determining whether the minimum circumscribed rectangle is biased to the left or to the right based on the reference coordinate system;

[0025] When the minimum circumscribed rectangle is biased to the left, obtaining a first left-side adjacent point and a second left-side adjacent point adjacent to the apex position point; and calibrating the apex position point according to the apex position point, the first left-side adjacent point, and the second left-side adjacent point to obtain a calibrated apex position point;

[0026] When the minimum circumscribed rectangle is biased to the right, a first right-side adjacent point and a second right-side adjacent point adjacent to the apex position point are obtained; and the apex position point is calibrated according to the apex position point, the first right-side adjacent point, and the second right-side adjacent point to obtain a calibrated apex position point.

[0027] In some possible implementations, determining the junction of the left ventricular septum and the mitral valve includes:

[0028] Determining a minimum circumscribed rectangle of the left ventricular contour and a center point of the minimum circumscribed rectangle;

[0029] Determine the point where a line connecting the center point of the minimum circumscribed rectangle and the lower left corner of the minimum circumscribed rectangle coincides with the left ventricular contour, and use the coincidence point as a second candidate point;

[0030] Selecting a plurality of left adjacent candidate points and a plurality of right adjacent candidate points adjacent to the second candidate point on the left ventricular contour;

[0031] The left ventricular septum and mitral valve junction point is determined according to the second candidate point, the multiple left adjacent candidate points, and the multiple right adjacent candidate points.

[0032] In some possible implementations, determining the junction point between the left ventricular septum and the mitral valve according to the second candidate point, the multiple left adjacent candidate points, and the multiple right adjacent candidate points includes:

[0033] Determine multiple point sets from the second candidate point, the multiple left-side adjacent candidate points, and the multiple right-side adjacent candidate points, each point set including the adjacent first candidate point, the second candidate point, and the third candidate point;

[0034] Determine a first slope between the first candidate point and the second candidate point and a second slope between the second candidate point and the third candidate point in each set of points;

[0035] A target point set having the largest difference between the first slope and the second slope is determined from the multiple point sets, and the second candidate point in the target point set is the junction point between the left ventricular septum and the mitral valve.

[0036] In some possible implementations, before determining the left ventricular parameters according to the left ventricular contour, the apex point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve, the method further includes:

[0037] Adjusting the left ventricular contour, the apex position point, the intersection point between the left ventricular septum and the mitral valve, and the intersection point between the left ventricular wall and the mitral valve to obtain adjusted left ventricular contour, adjusted apex position point, adjusted intersection point between the left ventricular septum and the mitral valve, and adjusted intersection point between the left ventricular wall and the mitral valve;

[0038] Then the left ventricular parameters determined according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve are:

[0039] The left ventricular parameters are determined according to the adjusted left ventricular contour, the adjusted apex position point, the adjusted left ventricular septum and mitral valve intersection point, and the adjusted left ventricular wall and mitral valve intersection point.

[0040] In another aspect, the present invention further provides a device for determining left ventricular parameters, comprising:

[0041] An ultrasonic cardiac data acquisition unit, configured to acquire two-dimensional ultrasonic cardiac data of a target object within a continuous time period, wherein the continuous time period is greater than one cardiac cycle, and the two-dimensional ultrasonic cardiac data includes multiple frames of two-dimensional ultrasonic cardiac images;

[0042] a target frame image determining unit, configured to determine a plurality of target frame images among the plurality of two-dimensional ultrasonic cardiac images, wherein the target frame images include a plurality of end-diastolic image frames corresponding to the end-diastole period and a plurality of end-systolic image frames corresponding to the end-systole period;

[0043] an image segmentation unit, configured to perform image segmentation on the target frame image to determine a left ventricular contour of the target frame image;

[0044] a key point determination unit, configured to determine the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve in the left ventricular contour;

[0045] A left ventricular parameter determination unit is used to determine left ventricular parameters according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve.

[0046] On the other hand, the present invention also provides an ultrasonic imaging device, comprising a memory and a processor, wherein:

[0047] The memory is used to store computer programs;

[0048] The processor is coupled to the memory and is configured to execute a computer program to implement the steps of the method for determining left ventricular parameters described in any one of the possible implementations above.

[0049] The beneficial effect of adopting the above embodiment is that the left ventricular parameter determination method provided by the present invention automatically determines the apex position point, the intersection point of the left ventricular septum and the mitral valve, and the intersection point of the left ventricular wall and the mitral valve in the left ventricular contour after determining the left ventricular contour of the target frame image. Compared with the semi-automatic measurement technology in the prior art that requires the doctor to manually select the above three points, the doctor's manual selection operation can be eliminated, simplifying the operation process, thereby improving the measurement efficiency. Furthermore, after determining the above three points, the present invention determines the left ventricular parameters based on the left ventricular contour, the apex position point, the intersection point of the left ventricular septum and the mitral valve, and the intersection point of the left ventricular wall and the mitral valve. Compared with the fully automatic measurement technology in the prior art that directly obtains the left ventricular parameters based on the left ventricular contour, the left ventricular parameters are obtained by using the three points and the left ventricular contour, which can improve the accuracy of the obtained left ventricular parameters. Therefore, the present invention takes into account both the measurement efficiency and accuracy of the left ventricular parameters. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative work.

[0051] Figure 1 A schematic flow chart of an embodiment of a method for determining left ventricular parameters provided by the present invention;

[0052] Figure 2 For the present invention Figure 1 A schematic flow chart of an embodiment of S103;

[0053] Figure 3 A schematic diagram of an embodiment of determining a target connected area provided by the present invention;

[0054] Figure 4 For the present invention Figure 1 A schematic diagram of an embodiment of a flow chart of determining the cardiac apex position point in S104;

[0055] Figure 5 A schematic diagram of an embodiment of the cardiac apex position point provided by the present invention;

[0056] Figure 6 For the present invention Figure 4 A schematic flow chart of an embodiment of S401;

[0057] Figure 7 A schematic diagram of another embodiment of the cardiac apex position point provided by the present invention;

[0058] Figure 8 A schematic diagram of a flow chart of an embodiment of calibrating the cardiac apex point provided by the present invention;

[0059] Figure 9 A schematic diagram of an embodiment of the present invention for determining whether the minimum circumscribed rectangle is biased to the left or right;

[0060] Figure 10 For the present invention Figure 1 A schematic diagram of an embodiment of a flow chart of determining the junction point between the left ventricular septum and the mitral valve in S104;

[0061] Figure 11 For the present invention Figure 10 A schematic flow chart of an embodiment of S1004;

[0062] Figure 12 A schematic structural diagram of an embodiment of a device for determining left ventricular parameters provided by the present invention;

[0063] Figure 13 This is a schematic structural diagram of an embodiment of the ultrasonic imaging device provided by the present invention. DETAILED DESCRIPTION

[0064] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making any creative efforts shall fall within the scope of protection of the present invention.

[0065] It should be understood that the schematic drawings are not drawn to scale. The flowcharts used in the present invention illustrate operations implemented according to some embodiments of the present invention. It should be understood that the operations in the flowcharts may be implemented out of sequence, and steps that do not have a logical contextual relationship may be reversed or performed simultaneously. In addition, those skilled in the art, guided by the present disclosure, may add one or more additional operations to the flowcharts or remove one or more operations from the flowcharts.

[0066] Some of the blocks shown in the accompanying drawings are functional entities that do not necessarily correspond to physically or logically independent entities. These functional entities may be implemented in software, in one or more hardware modules or integrated circuits, or in different networks and / or processor systems and / or microcontroller systems.

[0067] References herein to "embodiments" mean that a particular feature, structure, or characteristic described in connection with the embodiments may be included in at least one embodiment of the present invention. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor does it constitute a separate or alternative embodiment that is mutually exclusive of other embodiments. It is understood, both explicitly and implicitly, by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0068] The embodiments of the present invention provide a method and apparatus for determining left ventricular parameters and an ultrasonic imaging device, which are described below respectively.

[0069] Figure 1 A flow chart of an embodiment of the method for determining left ventricular parameters provided by the present invention is shown in FIG. Figure 1 As shown, the method for determining left ventricular parameters includes:

[0070] S101, collecting two-dimensional ultrasound cardiac data of a target subject within a continuous time period, where the continuous time period is greater than one cardiac cycle, the two-dimensional ultrasound cardiac data including multiple frames of two-dimensional ultrasound cardiac images;

[0071] S102, determining multiple target frame images among the multiple two-dimensional ultrasound cardiac image frames, where the target frame images include multiple end-diastolic image frames corresponding to the end-diastole and multiple end-systolic image frames corresponding to the end-systole;

[0072] S103, performing image segmentation on the target frame image to determine the left ventricular contour of the target frame image;

[0073] S104, determining the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve in the left ventricular contour;

[0074] S105 , determining left ventricular parameters according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve.

[0075] Compared with the prior art, the left ventricular parameter determination method provided by the embodiment of the present invention automatically determines the apex position point, the intersection point of the left ventricular septum and the mitral valve, and the intersection point of the left ventricular wall and the mitral valve in the left ventricular contour after determining the left ventricular contour of the target frame image. Compared with the semi-automatic measurement technology in the prior art that requires the doctor to manually select the above three points, this operation of manual selection by the doctor can be eliminated, simplifying the operation process, thereby improving measurement efficiency. Furthermore, after determining the above three points, the embodiment of the present invention determines the left ventricular parameters based on the left ventricular contour, the apex position point, the intersection point of the left ventricular septum and the mitral valve, and the intersection point of the left ventricular wall and the mitral valve. Compared with the fully automatic measurement technology in the prior art that directly obtains the left ventricular parameters based on the left ventricular contour, the left ventricular parameters are obtained by using the three points and the left ventricular contour, which can improve the accuracy of the obtained left ventricular parameters. Therefore, the embodiment of the present invention takes into account both the measurement efficiency and accuracy of the left ventricular parameters.

[0076] Step S101 may specifically include: acquiring two-dimensional ultrasound cardiac data from at least one medium selected from among multiple media such as an ultrasound system, DICOM, a workstation, a USB flash drive, and a mobile hard disk.

[0077] If the left ventricular parameters are determined by the Simpson single-plane measurement method in step S105, the continuous duration should be greater than one cardiac cycle. If the left ventricular parameters are determined by the Simpson double-plane measurement method in step S105, the continuous duration should be greater than two cardiac cycles, one of which is a two-chamber heart and the other is a four-chamber heart.

[0078] It should be understood that left ventricular parameters include, but are not limited to, left ventricular volume, volume index, and ejection fraction.

[0079] Since multiple connected regions may appear after image segmentation, it is necessary to determine the left ventricle region from the multiple connected regions. Therefore, in some embodiments of the present invention, for example, Figure 2 As shown, step S103 includes:

[0080] S201, performing image segmentation on the target frame image to obtain an initial left ventricular contour;

[0081] S202, preprocessing the initial left ventricular contour to obtain a left ventricular contour to be confirmed;

[0082] S203, determining whether the to-be-confirmed left ventricular contour includes multiple connected regions; if the to-be-confirmed left ventricular contour includes only one connected region, the connected region is the target connected region; if the to-be-confirmed left ventricular contour includes at least two connected regions, the connected region with the largest area is the target connected region;

[0083] S204: Extract the contour of the target connected area to obtain the left ventricle contour.

[0084] The embodiment of the present invention can improve the clarity and smoothness of the obtained initial left ventricular contour by preprocessing the initial left ventricular contour, thereby facilitating subsequent processing of the initial left ventricular contour.

[0085] The preprocessing includes but is not limited to smoothing, morphological filtering, and the like.

[0086] The determination of the maximum connected region in step S203 may be determined based on the area and / or perimeter.

[0087] In a specific embodiment of the present invention, step S204 may specifically include: finding the first non-zero point and the last non-zero point of each row by traversing the rows, and the contour formed by these non-zero points is the left ventricular contour.

[0088] The embodiment of the present invention can improve the accuracy of the obtained left ventricular contour by confirming the maximum connected area of ​​the initial left ventricular contour after image segmentation.

[0089] In a specific embodiment of the present invention, Figure 3 As shown, it can be seen that the original target frame image includes two connected areas (such as Figure 3 As shown on the left), after judging the connected area, the target connected area is as follows Figure 3 Shown on the right.

[0090] In some embodiments of the present invention, Figure 4 As shown, determining the apex position point in the left ventricular contour in step S104 includes:

[0091] S401, constructing a reference coordinate system based on the left ventricular contour, and determining at least one first candidate point having the smallest ordinate value in the left ventricular contour in the reference coordinate system;

[0092] S402: Using the ordinate of at least one first candidate point as the ordinate of the cardiac apex point, and using the average value of the abscissas of at least one first candidate point as the abscissa of the cardiac apex point.

[0093] The reference coordinate system in step S401 has the horizontal rightward direction as the positive direction of the abscissa axis and the vertical downward direction as the positive direction of the ordinate axis. Figure 5 As shown, there is only one first candidate point P3, and point P3 is the apex point.

[0094] Since the above method needs to traverse the ordinate values ​​of all points in the left ventricular contour, in order to simplify the calculation and further improve the measurement efficiency, in some embodiments of the present invention, such as Figure 6 As shown, step S401 includes:

[0095] S601, determining a minimum circumscribed rectangle of the left ventricular contour, and determining a plurality of intersection points between the minimum circumscribed rectangle and the left ventricular contour;

[0096] S602: Determine at least one first candidate point having the smallest ordinate value among multiple intersection points in the reference coordinate system.

[0097] The embodiment of the present invention determines at least one first candidate point from multiple intersection points of the minimum circumscribed rectangle and the left ventricular contour, without traversing all points on the left ventricular contour. Therefore, the speed of determining at least one first candidate point can be increased, thereby improving the measurement efficiency of the left ventricular contour.

[0098] In a specific embodiment of the present invention, Figure 7 As shown, the minimum circumscribed rectangle and the left ventricular contour include four intersection points, and the point P3 with the smallest ordinate value among the four intersection points is the apex position point.

[0099] In order to further improve the accuracy of the obtained cardiac apex position point, in some embodiments of the present invention, such as Figure 8 As shown, after step S402, the following steps are further included:

[0100] S801: Determine whether the minimum bounding rectangle is biased to the left or to the right based on the reference coordinate system;

[0101] S802: When the minimum circumscribed rectangle is biased to the left, obtain a first left-side adjacent point and a second left-side adjacent point adjacent to the apex position point; and calibrate the apex position point based on the apex position point, the first left-side adjacent point, and the second left-side adjacent point to obtain a calibrated apex position point.

[0102] S803: When the minimum circumscribed rectangle is biased to the right, obtain a first right-side adjacent point and a second right-side adjacent point adjacent to the apex position point; and calibrate the apex position point according to the apex position point, the first right-side adjacent point, and the second right-side adjacent point to obtain a calibrated apex position point.

[0103] In the embodiment of the present invention, by calibrating the cardiac apex position point when the minimum circumscribed rectangle is biased to the left or right, the accuracy of the obtained calibrated cardiac apex position point can be further improved.

[0104] Among them, step S801 can be specifically as follows: taking the vertical axis in the reference coordinate system as the starting point, determine whether the angle between the vertical axis in the reference coordinate system and the long side of the minimum circumscribed rectangle is positive or negative (counterclockwise is positive, clockwise is negative). When the angle is negative, the minimum circumscribed rectangle is biased to the right, and when the angle is positive, the minimum circumscribed rectangle is biased to the left.

[0105] In a specific embodiment of the present invention, Figure 9 As shown by Figure 9It can be seen from the figure that the angle θ between the ordinate axis and the long side of the minimum circumscribed rectangle in the reference coordinate system is positive, so Figure 9 The minimum enclosing rectangle in is biased to the left.

[0106] In a specific embodiment of the present invention, step S802 is specifically as follows: assuming that the coordinate value of the first left adjacent point P31 is (X31, Y31), and the coordinate value of the second left adjacent point P32 is (X32, Y32), then the coordinates (X3, Y3) of the calibration apex position point are:

[0107] If |X31-X3|≤1, then Y3=(Y3+Y31) / 2; X3=X31;

[0108] If |X32-X3|≤1, then Y3=(Y3+Y32) / 2; X3=X32.

[0109] In the formula, || is the absolute value operator.

[0110] When the minimum bounding rectangle is biased to the right, the calculation method is the same as when it is biased to the left, and will not be detailed here.

[0111] It should be noted that if the calibration apex position point is not on the left ventricular contour, then after determining the calibration apex position point, the calibration apex position point needs to be added to the left ventricular contour.

[0112] In some embodiments of the present invention, Figure 10 As shown, determining the junction point between the left ventricular septum and the mitral valve in step S104 includes:

[0113] S1001, determining the minimum circumscribed rectangle of the left ventricular contour and the center point of the minimum circumscribed rectangle;

[0114] S1002: Determine the point where the line connecting the center point of the minimum circumscribed rectangle and the lower left corner of the minimum circumscribed rectangle coincides with the left ventricular contour, and use the coincident point as the second candidate point.

[0115] S1003, selecting a plurality of left adjacent candidate points and a plurality of right adjacent candidate points adjacent to the second candidate point on the left ventricular contour;

[0116] S1004: Determine the junction point between the left ventricular septum and the mitral valve according to the second candidate point, a plurality of left adjacent candidate points, and a plurality of right adjacent candidate points.

[0117] It should be noted that the method for determining the coincident point in step S1002 can also be: determining the line equation connecting the lower left corner and the center point of the minimum circumscribed rectangle, traversing the points on the left ventricular contour, and then finding all points that satisfy the line equation. This point is the second candidate point. Alternatively, the left ventricular contour and the line equation can be drawn on two separate images, each of which is then binarized. Then, a pixel-by-pixel AND is performed on the two binarized images. The position where the result is 1 corresponds to the second candidate point. Of course, other common methods can also be used to determine the second candidate point, which will not be detailed here.

[0118] It should also be noted that the number of the multiple left-side adjacent candidate points and the number of the multiple right-side adjacent candidate points are the same, and the number can be adjusted according to actual conditions and is not specifically limited here.

[0119] In some embodiments of the present invention, Figure 11 As shown, step S1004 includes:

[0120] S1101, determining multiple point sets from the second candidate point, multiple left adjacent candidate points, and multiple right adjacent candidate points, each point set including the adjacent first candidate point, the second candidate point, and the third candidate point;

[0121] S1102, determining a first slope between the first candidate point and the second candidate point and a second slope between the second candidate point and the third candidate point in each point set;

[0122] S1103 . Determine a target point set having the largest difference between the first slope and the second slope from the multiple point sets, wherein the second candidate point in the target point set is the junction point between the left ventricular septum and the mitral valve.

[0123] It should be understood that the method for determining the junction point between the left ventricular wall and the mitral valve is the same as the method for determining the junction point between the left ventricular septum and the mitral valve. Please refer to the above-mentioned method for determining the junction point between the left ventricular septum and the mitral valve, and no detailed description will be given here.

[0124] Since there may be errors between the determined left ventricular contour, apex position point, junction point between the left ventricular septum and the mitral valve, and junction point between the left ventricular wall and the mitral valve and the actual left ventricular contour and actual point, before step S105, the following steps are further included:

[0125] Adjusting the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve to obtain the adjusted left ventricular contour, the adjusted apex position point, the adjusted junction point between the left ventricular septum and the mitral valve, and the adjusted junction point between the left ventricular wall and the mitral valve;

[0126] Then step S105 is:

[0127] The left ventricular parameters are determined by adjusting the left ventricular contour, adjusting the apex position point, adjusting the junction point between the left ventricular septum and the mitral valve, and adjusting the junction point between the left ventricular wall and the mitral valve.

[0128] The embodiment of the present invention can further improve the accuracy of the obtained left ventricular parameters by adjusting the left ventricular contour, adjusting the apex position point, adjusting the intersection point of the left ventricular septum and the mitral valve, and adjusting the intersection point of the left ventricular wall and the mitral valve.

[0129] In order to better implement the left ventricular parameter determination method in the embodiment of the present invention, based on the left ventricular parameter determination method, the embodiment of the present invention also provides a left ventricular parameter determination device, such as Figure 12 As shown, the left ventricular parameter determination device 1200 includes:

[0130] The ultrasonic cardiac data acquisition unit 1201 is used to acquire two-dimensional ultrasonic cardiac data of the target object within a continuous period, where the continuous period is greater than one cardiac cycle, and the two-dimensional ultrasonic cardiac data includes multiple frames of two-dimensional ultrasonic cardiac images;

[0131] The target frame image determining unit 1202 is configured to determine multiple target frame images from the multiple two-dimensional ultrasound image frames, where the target frame images include multiple end-diastolic image frames corresponding to the end-diastole and multiple end-systolic image frames corresponding to the end-systole.

[0132] An image segmentation unit 1203 is configured to segment the target frame image and determine the left ventricle contour of the target frame image;

[0133] A key point determination unit 1204 is used to determine the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve in the left ventricular contour;

[0134] The left ventricular parameter determination unit 1205 is configured to determine the left ventricular parameters according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve.

[0135] The left ventricular parameter determination device 1200 provided in the above embodiment can implement the technical solution described in the above left ventricular parameter determination method embodiment. The specific implementation principles of the above modules or units can refer to the corresponding contents in the above left ventricular parameter determination method embodiment, which will not be repeated here.

[0136] like Figure 13 As shown, the present invention also provides an ultrasonic imaging device 1300. The ultrasonic imaging device 1300 includes a processor 1301, a memory 1302 and a display 1303. Figure 13Only some of the components of the ultrasound imaging device 1300 are shown, but it should be understood that implementation of all of the shown components is not required, and more or fewer components may be implemented instead.

[0137] In some embodiments, the memory 1302 may be an internal storage unit of the ultrasound imaging device 1300, such as a hard disk or memory of the ultrasound imaging device 1300. In other embodiments, the memory 1302 may also be an external storage device of the ultrasound imaging device 1300, such as a plug-in hard disk, a Smart Media Card (SMC), a Secure Digital (SD) card, a flash card, etc. equipped on the ultrasound imaging device 1300.

[0138] In some embodiments, the processor 1301 can be a central processing unit (CPU), a microprocessor or other data processing chip, used to run the program code stored in the memory 1302 or process data, such as the vehicle CAN bus fault frame analysis method in the present invention.

[0139] The display 1303 is used to display information on the ultrasonic imaging device 1300 and to display a visual user interface. The components 1301-1303 of the ultrasonic imaging device 1300 communicate with each other via a system bus.

[0140] In one embodiment, when the processor 1301 executes the left ventricular parameter determination program in the memory 1302 , the steps S101 to S105 may be implemented.

[0141] It should be understood that, when the processor 1301 executes the left ventricular parameter determination program in the memory 1302 , in addition to the above functions, it can also implement other functions. For details, please refer to the description of the corresponding method embodiment above.

[0142] Those skilled in the art will appreciate that all or part of the process steps of the above-described embodiments can be implemented by instructing related hardware (such as a processor, a controller, etc.) through a computer program, and the computer program can be stored in a computer-readable storage medium. The computer-readable storage medium may be a magnetic disk, an optical disk, a read-only memory, or a random access memory.

[0143] The above is a detailed introduction to the left ventricular parameter determination method, device and ultrasonic imaging equipment provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core ideas. At the same time, for those skilled in the art, based on the ideas of the present invention, there may be changes in the specific implementation methods and application scopes. In summary, the contents of this specification should not be understood as limiting the present invention.

Claims

1. A method for determining left ventricular parameters, characterized in that: include: Acquiring two-dimensional ultrasound cardiac data of a target object within a continuous time period, wherein the continuous time period is greater than one cardiac cycle, and the two-dimensional ultrasound cardiac data includes multiple frames of two-dimensional ultrasound cardiac images; Determining a plurality of target frame images among the plurality of two-dimensional ultrasound cardiac image frames, wherein the target frame images include a plurality of end-diastolic image frames corresponding to the end-diastole and a plurality of end-systolic image frames corresponding to the end-systole; performing image segmentation on the target frame image to determine the left ventricular contour of the target frame image; constructing a reference coordinate system based on the left ventricular contour, and determining at least one first candidate point having the smallest ordinate value in the left ventricular contour in the reference coordinate system; Using the ordinate of the at least one first candidate point as the ordinate of the cardiac apex point, and using the average of the abscissas of the at least one first candidate point as the abscissa of the cardiac apex point; Determining a minimum circumscribed rectangle of the left ventricular contour and a center point of the minimum circumscribed rectangle; Determine the point where a line connecting the center point of the minimum circumscribed rectangle and the lower left corner of the minimum circumscribed rectangle coincides with the left ventricular contour, and use the coincidence point as a second candidate point; Selecting a plurality of left adjacent candidate points and a plurality of right adjacent candidate points adjacent to the second candidate point on the left ventricular contour; Determine multiple groups of point sets from the second candidate point, the multiple left-side adjacent candidate points, and the multiple right-side adjacent candidate points, each group of point sets including the adjacent first candidate point, second candidate point, and third candidate point; determine a first slope between the first candidate point and the second candidate point, and a second slope between the second candidate point and the third candidate point, in each group of point sets; determine a target point set from the multiple groups of point sets, wherein the second candidate point in the target point set is the junction of the left ventricular septum and the mitral valve; The left ventricular parameters are determined according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve.

2. The method for determining left ventricular parameters according to claim 1, wherein: The performing image segmentation on the target frame image to determine the left ventricular contour of the target frame image includes: Performing image segmentation on the target frame image to obtain an initial left ventricular contour; Preprocessing the initial left ventricular contour to obtain a left ventricular contour to be confirmed; determining whether the to-be-confirmed left ventricular contour includes multiple connected regions; if the to-be-confirmed left ventricular contour includes only one connected region, the connected region is the target connected region; if the to-be-confirmed left ventricular contour includes at least two connected regions, the connected region with the largest area is the target connected region; The contour of the target connected area is extracted to obtain the left ventricle contour.

3. The method for determining left ventricular parameters according to claim 1, wherein: The determining of at least one first candidate point having the smallest ordinate value in the left ventricular contour in the reference coordinate system comprises: determining a minimum circumscribed rectangle of the left ventricular contour, and determining a plurality of intersection points between the minimum circumscribed rectangle and the left ventricular contour; At least one first candidate point having the smallest ordinate value among the plurality of intersection points in the reference coordinate system is determined.

4. The method for determining left ventricular parameters according to claim 3, wherein: After taking the ordinate of the at least one first candidate point as the ordinate of the cardiac apex position point and taking the average of the abscissas of the at least one first candidate point as the abscissa of the cardiac apex position point, the method further includes: Determining whether the minimum circumscribed rectangle is biased to the left or to the right based on the reference coordinate system; When the minimum circumscribed rectangle is biased to the left, obtaining a first left-side adjacent point and a second left-side adjacent point adjacent to the apex position point; and calibrating the apex position point according to the apex position point, the first left-side adjacent point, and the second left-side adjacent point to obtain a calibrated apex position point; When the minimum circumscribed rectangle is biased to the right, a first right-side adjacent point and a second right-side adjacent point adjacent to the apex position point are obtained; and the apex position point is calibrated according to the apex position point, the first right-side adjacent point, and the second right-side adjacent point to obtain a calibrated apex position point.

5. The method for determining left ventricular parameters according to claim 1, wherein: Before determining the left ventricular parameters according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve, the method further includes: Adjusting the left ventricular contour, the apex position point, the intersection point between the left ventricular septum and the mitral valve, and the intersection point between the left ventricular wall and the mitral valve to obtain adjusted left ventricular contour, adjusted apex position point, adjusted intersection point between the left ventricular septum and the mitral valve, and adjusted intersection point between the left ventricular wall and the mitral valve; Then the left ventricular parameters determined according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve are: The left ventricular parameters are determined according to the adjusted left ventricular contour, the adjusted apex position point, the adjusted left ventricular septum and mitral valve intersection point, and the adjusted left ventricular wall and mitral valve intersection point.

6. A device for determining left ventricular parameters, characterized in that: include: An ultrasonic cardiac data acquisition unit, configured to acquire two-dimensional ultrasonic cardiac data of a target object within a continuous time period, wherein the continuous time period is greater than one cardiac cycle, and the two-dimensional ultrasonic cardiac data includes multiple frames of two-dimensional ultrasonic cardiac images; a target frame image determining unit, configured to determine a plurality of target frame images among the plurality of two-dimensional ultrasonic cardiac images, wherein the target frame images include a plurality of end-diastolic image frames corresponding to the end-diastole period and a plurality of end-systolic image frames corresponding to the end-systole period; an image segmentation unit, configured to perform image segmentation on the target frame image to determine a left ventricular contour of the target frame image; a point determination unit, configured to construct a reference coordinate system based on the left ventricular contour, and determine at least one first candidate point having the smallest ordinate value in the left ventricular contour in the reference coordinate system; Using the ordinate of the at least one first candidate point as the ordinate of the cardiac apex point, and using the average of the abscissas of the at least one first candidate point as the abscissa of the cardiac apex point; Determining a minimum circumscribed rectangle of the left ventricular contour and a center point of the minimum circumscribed rectangle; Determine the point where a line connecting the center point of the minimum circumscribed rectangle and the lower left corner of the minimum circumscribed rectangle coincides with the left ventricular contour, and use the coincidence point as a second candidate point; Selecting a plurality of left adjacent candidate points and a plurality of right adjacent candidate points adjacent to the second candidate point on the left ventricular contour; Determine multiple groups of point sets from the second candidate point, the multiple left-side adjacent candidate points, and the multiple right-side adjacent candidate points, each group of point sets including the adjacent first candidate point, second candidate point, and third candidate point; determine a first slope between the first candidate point and the second candidate point, and a second slope between the second candidate point and the third candidate point, in each group of point sets; determine a target point set from the multiple groups of point sets, wherein the second candidate point in the target point set is the junction of the left ventricular septum and the mitral valve; A left ventricular parameter determination unit is used to determine left ventricular parameters according to the left ventricular contour, the apex position point, the junction point between the left ventricular septum and the mitral valve, and the junction point between the left ventricular wall and the mitral valve.

7. An ultrasonic imaging device, characterized in that: comprising a memory and a processor, wherein, The memory is used to store computer programs; The processor, coupled to the memory, is configured to execute a computer program to implement the steps of the method for determining left ventricular parameters according to any one of claims 1 to 5.

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