Ophthalmic lens with extended depth of focus for improving intermediate vision

Abstract

The present disclosure provides an ophthalmic lens (such as an IOL) designed to enhance the depth of focus of intermediate vision performance while maintaining distance vision. The lens may include an optical device having an anterior surface and a posterior surface disposed about an optical axis. One of the surfaces (e.g., the anterior surface) may have a surface profile that includes a superposition of at least three structures or profiles, including: a base structure; a phase-shifting structure having an inner region, an outer region, and a transition region; and a zone structure having an inner power region and an outer transition region.

Description

[0001] Priority Declaration

[0002] This application claims the benefit of priority to U.S. Provisional Patent Application Serial No. 63 / 010,792, filed on April 16, 2020, entitled “OPHTHALMIC LENSES HAVING AN EXTENDEDDEPTH OF FOCUS FOR IMPROVING INTERMEDIATE VISION,” inventors Myoung-Taek Choi, Sangyeol Lee, Shinwook Lee, and William Lee, which is hereby incorporated by reference in its entirety as if fully and completely set forth herein. Technical Field

[0003] The present disclosure relates generally to the field of ophthalmic lenses, and more particularly to lenses with extended depth of focus for improving intermediate vision. Background Art

[0004] Ophthalmic lenses, such as intraocular lenses, are routinely implanted in a patient's eye during cataract surgery to replace the natural lens. The optical power of the natural lens can be varied under the influence of the ciliary muscle, providing accommodation for viewing objects at different distances from the eye. Many intraocular lenses provide improved distance vision performance, but may not provide the extended depth of focus that provides intermediate vision. Summary of the Invention

[0005] The present disclosure generally relates to an ophthalmic lens, such as an IOL, that enhances depth of focus for intermediate vision performance while maintaining distance vision.

[0006] According to the present disclosure, a lens includes an optical device having a front surface and a back surface disposed about an optical axis, at least one of the front and back surfaces having a surface profile corresponding to a superposition of at least three profiles. The three profiles include a phase-shifting structure, a zone structure, and a base structure or curvature. The phase-shifting structure is characterized by an inner region, an outer region, and a transition region. The inner region extends radially from the optical axis to a first boundary. The transition region is disposed between the inner and outer regions and extends radially from the first boundary to a second boundary, wherein the transition region is adapted to linearly vary the phase of radiation incident thereon over at least a portion of the radial range between the first boundary and the second boundary to produce a phase shift between the first boundary and the second boundary. The second boundary is disposed at a radial distance farther from the optical axis than the first boundary. The outer region extends radially from the second boundary toward an outermost edge of the optical device. The zone structure includes an inner power region having a first curvature and an outer transition region having a second curvature. The inner power region extends radially from the optical axis to the second boundary, and the outer transition region extends radially to a third boundary. The third boundary is disposed at a radial distance farther from the optical axis than the second boundary.The base curvature extends radially from the third boundary to an outermost edge of the optical device. BRIEF DESCRIPTION OF THE DRAWINGS

[0007] Figure 1A illustrates a top view of an example embodiment of an ophthalmic lens according to the present disclosure;

[0008] Figure 1B illustrates a side view of an example embodiment of an ophthalmic lens according to the present disclosure;

[0009] Figure 2 An exploded cross-sectional view showing the layers and resultant loss of height of an example optical device according to the present disclosure;

[0010] Figure 3A A graph showing surface loss height versus radial distance from the optical axis for a phase shifting structure of an example optical device according to the present disclosure;

[0011] Figure 3B showing a graph of surface loss height versus radial distance from the optical axis for a regional structure of an example optical device according to the present disclosure;

[0012] Figure 3C shows a graph of composite surface loss height versus radial distance from the optical axis for an example optical device according to the present disclosure;

[0013] Figure 4A shows a graph of the through-focus modulation transfer function (MTF) of a conventional monofocal IOL according to the present disclosure;

[0014] Figure 4Bshows a through-focus MTF curve of an optical device having only a phase shift structure according to the present disclosure;

[0015] Figure 4C shows a through-focus MTF graph of an optical device having only a zone power structure according to the present disclosure;

[0016] Figure 4D shows a through-focus MTF graph of an example optical device according to the present disclosure; and

[0017] Figure 5 A graph of visual acuity (VA) versus defocus is shown and depicts the depth of focus extension of an example optic in accordance with the present disclosure.

[0018] As understood by those skilled in the art, the drawings described below are for illustration purposes only and are not intended to limit the scope of the present disclosure. DETAILED DESCRIPTION

[0019] An intraocular lens (IOL) is the most common type of lens used in cataract surgery. A monofocal IOL is an intraocular lens that has a single focus at one distance, for example, near focus, intermediate focus, or far focus. Because monofocal IOLs can only be set for one distance, and because most patients and practitioners choose far focus, patients may need to utilize additional eyewear to correct near vision and / or intermediate vision. Additionally, as the human eye ages, the depth of focus decreases. The depth of focus (measured in diopters (D)) is the total distance in front of and behind the focal point at which an image can be focused without causing a loss of clarity beyond a certain tolerable amount. Traditional monofocal IOLs are limited in their ability to extend the depth of focus.

[0020] The present disclosure generally relates to an ophthalmic lens (such as a monofocal IOL) whose surface profile maintains distance vision image quality while improving intermediate vision and further extends the depth of focus. Although the following disclosure is described in conjunction with an IOL, it should be understood that the features and elements of the present disclosure are not limited to any particular type of IOL and can be applied to monofocal or multifocal IOLs. In addition, the present disclosure can be further applied to non-IOL ophthalmic lenses, such as contact lenses. Furthermore, as used herein, the term "intraocular lens" (and its abbreviation IOL) is used to describe a lens that is implanted inside the eye to replace the eye's natural lens or otherwise enhance vision, regardless of whether the natural lens is removed.

[0021] Now refer to Figure 1A and Figure 1B , which depicts an example embodiment of an intraocular lens 100 according to the present disclosure. Figure 1A depicts a top view of the front surface 130 of the lens 100, and Figure 1BA side view showing the front surface 130 and the back surface 140 of the lens 100 is depicted. The lens 100 may include a plurality of haptics 110, which are generally operable to position and stabilize the lens 100 within the capsular bag of the patient's eye. The lens 100 may further include an optic 120 having a front surface 130 and a back surface 140 disposed about the optical axis 105 of the lens. Figure 1A and Figure 1B As shown, the optical axis 105 passes through the geometric center of the optical device 120. One of the front surface 130 and the back surface 140 may include an aspherical or spherical surface profile, while the other surface may include a multi-layer surface profile formed by the superposition of three profiles or structures. For illustrative purposes, the multi-layer surface profile is depicted in FIG. Figure 1A However, it should be understood that in combination with the front surface 130 of the optical device 120 Figure 1A The multi-layer surface profile shown and described may alternatively be applied on the back surface 140 of the optic 120 , and an aspheric or spherical surface profile may be applied on the front surface 130 of the optic 120 .

[0022] Now combine Figure 2 For reference Figure 1A . Figure 2 An exploded cross-sectional view is shown illustrating the various layers or structures 150 , 160 , 170 forming the multi-layered surface profile of the front surface 130 of the optical device 120 , as well as the composite or resultant loss of height 180 of the front surface 130 of the optical device 120 . Figure 1A A top view (top view) of the composite multilayer surface profile of the front surface 130 of the optical device 120 is shown, wherein Figure 1A The radial boundaries 122, 124, 126, 128 in correspond to Figure 2 The boundaries of structures 150, 160, and 170. Figure 2 In the embodiment of the present invention, it should be understood that the left and right sides of the optical axis 105 are mirror images of each other. Therefore, the structures, boundaries, and names shown on a given side of the optical axis 105 can also apply to the other side of the optical axis 105.

[0023] The multi-layer surface profile of the front surface 130 may include a superposition of at least three profiles or structures: a phase shifting structure 150; an aspheric zone structure 160; and an aspheric base structure 170. The zone structure 160 may further include a superposition of an inner power zone 162 and an outer transition zone 164. As described above, each of these structures may be defined in conjunction with a plurality of radial boundaries 122, 124, 126, 128 formed at increasing radial distances from the optical axis 105 of the optical device 120. The multi-layer surface profile (Z) of the front surface 130 of the optical device 120 may be a phase shifting structure 150; an aspheric zone structure 160; and an aspheric base structure 170. The zone structure 160 may further include a superposition of an inner power zone 162 and an outer transition zone 164. As described above, each of these structures may be defined in conjunction with a plurality of radial boundaries 122, 124, 126, 128 formed at increasing radial distances from the optical axis 105 of the optical device 120. total) (including the phase shift structure 150, the region structure 160 and the base structure 170) can be defined by the following equation:

[0024] Equation (1) Z total =Z aux +Z zone1 +Z zone2 +Z base ,

[0025] in,

[0026] Z aux represents the surface profile of the phase shift structure 150;

[0027] Z zone1 represents the surface profile of the inner focal region 162 of the domain structure 160;

[0028] Z zone2 represents the surface profile of the outer transition region 164 of the domain structure 160; and Z base The surface profile of the base structure 170 is shown.

[0029] Each of these structures 150 , 160 , 170 will be described in turn.

[0030] First, the phase shift structure 150 may include a trapezoidal phase shift (TPS) feature having an inner region 152, a transition region 154, and an outer region 156. The inner region 152 may extend radially from the optical axis 150 to a first radial boundary 122. The transition region 154 may extend radially from the first radial boundary 122 to a second radial boundary 124, the second radial boundary being disposed at a radial distance further from the optical axis 105 than the first radial boundary 122. The transition region 154 may be configured such that the phase of radiation incident thereon varies linearly over at least a portion of the radial range between the first radial boundary 122 and the second radial boundary 124 to produce a phase shift between the first radial boundary 122 and the second radial boundary 124. The outer region 156 of the phase shift structure 150 may extend radially from the second radial boundary 124 to the outermost edge 128 of the optical device 120.

[0031] Figure 2 The trapezoidal phase shift structure 150 shown in FIG can be defined by the following equation:

[0032] Equation (2a)

[0033] in,

[0034] r represents the radial distance from the optical axis 105 of the optical device 120,

[0035] r1 represents the radial distance from the optical axis 105 to the first radial boundary 122;

[0036] r2 represents the radial distance from the optical axis 105 to the second radial boundary 124; and

[0037] Δ represents the step height of the phase shift structure 150 relative to the inner region 152;

[0038] And among them,

[0039] Δ is defined by the following relationship:

[0040] Equation (2b)

[0041] in,

[0042] n1 represents the refractive index of the material forming the optical device,

[0043] n2 represents the refractive index of the medium surrounding the optical device,

[0044] λ is the design wavelength, and

[0045] α represents a non-integer decimal.

[0046] In an embodiment, the phase shift structure 150 defined by equations (2a) and (2b) is characterized by a substantially linear phase shift across the transition region 154. More specifically, the phase shift structure 150 provides a phase shift that increases linearly from an inner boundary of the transition region 154 (corresponding to the first radial boundary 122) to an outer boundary of the transition region 154 (corresponding to the second radial boundary 124), wherein the optical path difference between the inner boundary and the outer boundary (or between the first and second radial boundaries 122, 124) corresponds to a non-integer decimal of the design wavelength.

[0047] In operation, the trapezoidal phase-shifting structure 150 can generate a continuous focal shift by virtue of the advancing wavefront retardation between the inner region 152 and the outer region 156, which results in a collective depth of focus extension. The phase-shifting structure can generate different amounts of phase shift in light waves passing through the optical device 120 (depending on the region of the optical device 120 through which the light waves pass), and the structural interference between the light waves with different amounts of phase shift can produce an extended depth of focus. As described below, additional depth of focus extension can be achieved by adding an inner focal power region 162 of the regional structure 160 to the phase-shifting structure 150. In this case, the phase-shifting structure 150 can help mitigate undesirable pupil-related focal shift that may result from the enhanced depth of focus extension caused by the inner focal power region 162. Additionally, without the trapezoidal phase-shifting structure 150, the optical device 120 would essentially function as a bifocal design.

[0048] In one embodiment, the radial distance r1 of the inner region 152 of the phase shift structure 150 (from the optical axis 105 to the first radial boundary 122) can include a value ranging from approximately 0.45 mm to 0.75 mm. The radial distance r2 from the optical axis 105 to the second radial boundary 124 can include a value ranging from approximately 0.75 mm to 1.05 mm. In addition, the step height Δ of the phase shift structure 150 can be approximately -2.1 μm.

[0049] Continue to combine Figure 2 For reference Figure 1A , the regional structure 160 may include an inner focal power region 162 and an outer transition region 164. The inner focal power region 162 may have a first curvature and may extend radially from the optical axis 105 to the second radial boundary 124, and as shown Figure 2 As shown, the inner region and transition regions 152 and 154 of the phase-shifting structure 150 may overlap. The inner power zone 162 may include a refractive surface and may be configured to enhance depth of focus for improving intermediate vision performance. Specifically, while the trapezoidal phase-shifting structure 150 itself may improve depth of focus and visual acuity for intermediate vision, the inner power zone 162 (having a higher optical power than the base structure 170) may produce an add power effect that, when combined with the phase-shifting structure 150, may further increase depth of focus and improve intermediate vision. Furthermore, the combination of the trapezoidal phase-shifting structure 150 and the inner power zone 162 allows the optical device to flexibly control intermediate vision in terms of both focal length and power. In an embodiment, the inner power zone 162 is positioned in the innermost region of the optical device 120. This positioning is particularly important for extending depth of focus and improving visual acuity. In an embodiment, the add power in the inner power zone 162 may range from 0.7D to 2.4D. In an embodiment, the inner power zone 162 may extend the depth of focus up to 2.38D and improve visual acuity by 0.2 for pupil diameters of 2 mm to 6 mm.

[0050] In an embodiment, Figure 2 The inner power zone 162 shown in FIG. 1 may be defined by the following equation:

[0051] Equation (3)

[0052] in,

[0053] r represents the radial distance from the optical axis 105 of the optical device 120,

[0054] c1 represents the base curvature of the inner focal power zone 162,

[0055] k1 represents the cone constant,

[0056] r2 represents the radial distance from the optical axis 105 to the second radial boundary 124,

[0057] A4' is the fourth-order aspheric coefficient, and

[0058] A6' is the sixth-order aspheric coefficient.

[0059] In an embodiment, r2 may include a value ranging from approximately 0.45 mm to 0.80 mm. In an embodiment, the value of r2 in equation (3) for the inner focal zone 162 may be substantially equal to the value of r2 in equation (2a) for the trapezoidal phase shift structure 150. In another embodiment, there may be some degree of variation between the value of r2 in equation (3) for the inner focal zone 162 and the value of r2 in equation (2a) for the trapezoidal phase shift structure 150. Therefore, in some embodiments, the position of the second radial boundary 124 may be understood as a reference point that may vary or be different relative to various structures, such as the phase shift structure 150 and the regional structure 160 of the optical device 120. The base curvature c1 of the inner focal zone 162 may include a value ranging from approximately 19.0 mm to approximately 19.0 mm. -1 to 20.2mm -1 For example, a mid-power diopter value of 21D. The value of the cone constant k1 can range from about -100 to -30. The fourth-order aspheric coefficient A4' can range from about -6.5×10 -4 mm -3 to -1.0×10 -4 mm -3 The sixth-order aspheric coefficient A6' may include a range from approximately -1.0×10 -5 mm -5 to 3.0×10 -5 mm -5 In an embodiment, the fourth-order and sixth-order aspheric coefficients may be selected to optimize the spherical aberration of the optical device 120.

[0060] The regional structure 160 may further include an outer transition region 164 having a second curvature. Figure 2 As shown in the cross-sectional view of FIG, the outer transition region 164 can functionally extend radially from the second boundary 124 to the third boundary 126, wherein the third boundary 126 is disposed at a radial distance farther from the optical axis 105 than the second boundary 124. Figure 2The functional boundaries of the outer transition zone 164 are depicted as extending radially from the second radial boundary 124 to the third radial boundary 126, but it should be understood that the structure forming the outer transition zone 164 technically extends radially from the optical axis 105 to the third radial boundary 126. However, the innermost region 164a of the outer transition zone 164 from the optical axis 105 to the second radial boundary 124 (depicted by the dashed line) does not functionally contribute to the multi-layer surface profile of the front surface 130 of the optic 120. In other words, only the outermost region 164b of the outer transition zone 164 functionally contributes to the resultant loss of height 180 of the multi-layer surface profile of the front surface 130. The outer transition zone 164 may include a refractive surface and may be used to provide a smooth transition from the inner power zone 162 to the base structure 170.

[0061] In some embodiments, the outer transition zone 164 can be excluded from the design of the optical device 120. In such embodiments, it should be understood that the remaining structures (e.g., the phase-shifting structure 150, the inner power zone 162, and / or the base structure 170) can be modified to provide an appropriate transition from the inner power zone 162 to the base structure 170. For example, the base structure 170 (described below) can be modified to functionally begin at the second radial boundary 124 (rather than the third radial boundary 126) and can extend radially to the outermost edge 128 of the optical device. As a further example, the superposition of the outer portion 162b of the inner power zone 162 of the zone structure 160 and the transition zone 154 of the phase-shifting structure 150 can provide a transition from the inner power zone 162 to the base structure 170. It should be understood that these and other modifications to the optical device are considered to be within the scope of the present disclosure.

[0062] Figure 2 The outer transition region 164 shown in FIG can be defined by the following equation:

[0063] Equation (4)

[0064] in,

[0065] r represents the radial distance from the optical axis 105 of the optical device 120,

[0066] c2 represents the base curvature of the outer transition region 164,

[0067] k2 represents the cone constant,

[0068] r2 represents the radial distance from the optical axis 105 to the second radial boundary 124,

[0069] r3 represents the radial distance from the optical axis 105 to the third radial boundary 126,

[0070] A4" is the fourth-order aspheric coefficient, and

[0071] A6" is the sixth-order aspheric coefficient.

[0072] In an embodiment, the radial distance r2 from the optical axis 105 to the second radial boundary 124 may include a value ranging from approximately 0.45 mm to 0.80 mm. In one embodiment, the value of r2 in equation (4) of the outer transition zone 162 may be substantially equal to the value of r2 in equation (2a) of the trapezoidal phase shift structure 150. In another embodiment, there may be some degree of variation between the value of r2 in equation (4) of the outer transition zone 162 and the value of r2 in equation (2a) of the trapezoidal phase shift structure 150. The radial distance r3 from the optical axis 105 to the third radial boundary 126 may include a value ranging from approximately 0.60 mm to 1.2 mm. The base curvature c2 of the outer transition zone 164 may include a value ranging from approximately 20.0 mm to 30.0 mm. -1 to 20.5mm -1 The value of the cone constant k2 can range from about -100 to -30. The fourth-order aspheric coefficient A4" can range from -6.5×10 -4 mm -3 to -1.0×10 -4 mm -3 The sixth-order aspheric coefficient A6" may include a range from approximately -1.0×10 -5 mm -5 to 3.0×10 -5 mm -5 The value of .

[0073] Continue to combine Figure 2 For reference Figure 1A , the base structure 170 may include a third profile or structure of the multi-layer surface profile of the front surface 130 of the optical device 120. In some embodiments, the base structure 170 may be in the form of a base curvature. Figure 2 As shown in the cross-sectional view of FIG, the base structure 170 can functionally extend radially from the third radial boundary 126 to the outermost edge 128 of the optical device. Figure 2 The functional boundaries of the base curvature or base structure 170 are depicted (i.e., extending radially from the third radial boundary 126 to the outermost edge 128 of the optic), but it should be understood that the base structure 170 technically extends radially from the optical axis 105 to the outermost edge 128 of the optic 120. However, the innermost region 170a of the base structure 170 (depicted by the dashed line, from the optical axis 105 to the third radial boundary 126) does not functionally contribute to the multi-layer surface profile of the front surface 130 of the optic 120. In other words, only the outermost region 170b of the base structure 170 functionally contributes to the resultant loss of height 180 of the multi-layer surface profile of the front surface 130.

[0074] In an embodiment, the base structure 170 may include an aspheric surface profile having a base lens power, as understood in the art. In an embodiment, the base structure may have an optical power ranging from -15D to +50D.

[0075] Figure 2 The base structure 170 shown in FIG can be defined by the following equation:

[0076] Equation (5)

[0077] in,

[0078] r represents the radial distance from the optical axis 105 of the optical device 120,

[0079] c represents the curvature of the base structure 170,

[0080] k represents the cone constant,

[0081] r3 represents the radial distance from the optical axis to the third boundary 126,

[0082] A4 is the fourth-order aspheric coefficient, and

[0083] A6 is the sixth-order aspheric coefficient.

[0084] In an embodiment, the radial distance r3 from the optical axis 105 to the third radial boundary 126 may comprise a value ranging from approximately 0.60 mm to 1.2 mm. The base curvature c of the base structure 170 may comprise a value ranging from approximately 0.0152 mm to approximately 1.2 mm. -1 To about 0.0659mm -1 The cone constant k may include a value ranging from about -1162 to about -19. The fourth-order aspheric coefficient A4 may include a value ranging from about 0.0 mm -3 to approximately -5.3×10 -3 mm -3 The sixth-order aspheric coefficient A6 may include a range from approximately 0.0 mm -3 to approximately 1.53×10 -4 mm -5 The value of .

[0085] Further references Figure 2 As described above, the superposition of structures 150, 160, 170 can produce a composite multi-layer surface profile (in Figure 2180). The composite loss of height 180 may further correspond to first, second, third, and fourth regions 182, 184, 186, 188 defined by radial boundaries 122, 124, 126, 128, respectively. Each of the first, second, third, and fourth regions 182, 184, 186, 188 of the composite loss of height 180 may result from a composite contribution of one or more of the structures 150, 160, 170 described above.

[0086] For example, a first region 182 of the synthetic loss of height 180 can be defined as a region extending radially from the optical axis 105 to the first radial boundary 122. In one embodiment, the first region 182 can be formed by the superposition of the inner region 152 of the phase shifting structure 150 and the inner portion 162a of the inner power zone 162 of the zone structure 160. In one embodiment, the first region 182 may not include contributions from the outer transition zone 164 of the zone structure 160 (e.g., the innermost region 164a of the outer transition zone 164) or from the base structure 170 (e.g., the innermost region 170a of the base structure) because, as described above, the innermost region 164a of the outer transition zone 164 and the innermost region 170a of the base structure do not functionally contribute to the synthetic loss of height 180 of the first region 182. In yet another embodiment, the first region 182 of the synthetic loss of height 180 can be defined solely by the inner power zone 162, more specifically, the inner portion 162a of the inner power zone 162. In other words, the inner region 152 of the phase shifting structure may not functionally contribute to the resultant loss of height.The first region 182 may include a first composite aspheric profile.

[0087] A second region 184 of the resultant loss of height 180 can be defined as a region extending radially from the first radial boundary 122 to the second radial boundary 124. In embodiments, the second region 184 can be formed by the superposition of the transition region 154 of the phase-shifting structure 150 and the outer portion 162b of the inner power zone 162 of the zone structure 160. In embodiments, the second region 184 can include no contribution from the outer transition zone 164 of the zone structure 160 (e.g., the innermost region 164a of the outer transition zone 164) or from the base structure 170 (e.g., the innermost region 170a of the base structure) because the innermost region 164a of the outer transition zone 164 and the innermost region 170a of the base structure 170 functionally do not contribute to the resultant loss of height 180 of the second region 184. The transition region 154 (having a single-step phase shift), when combined with the outer portion 162b of the inner power zone 162, can allow the resultant second region 184 to function as a transition from the first region 182 to the third region 186. The second region 184 may include a second composite aspheric profile.

[0088] Continue to refer Figure 2 , a third region 186 of the composite loss of height 180 can be defined as a region extending radially from the second radial boundary 124 to the third radial boundary 126. In one embodiment, the third region 186 can be formed by the superposition of the outermost region 164b of the outer transition zone 164 of the regional structure 160 and the outer region 156 of the phase shift structure 150. The third region 186 (which is the combination of the outermost region 164b of the outer transition zone 164 and the outer region 156) can serve as a transition from the second region 184 to the fourth region 188. In one embodiment, the third region 186 may not include a contribution from the base structure 170 (e.g., the innermost region 170a of the base structure) because the innermost region 170a of the base structure does not functionally contribute to the composite loss of height 180 of the third region 186. In yet another embodiment, the third region 186 may be defined solely by the outer transition zone 164 of the regional structure 160, more specifically, the outermost region 164b of the outer transition zone 164. In other words, the outer region 156 of the phase shift structure may not functionally contribute to the resultant loss of height.The third region 186 may include a third composite aspheric profile.

[0089] A fourth region 188 of the resultant loss of height 180 can be defined as a region extending radially from the third radial boundary 126 to the outermost edge 128 of the optic. In one embodiment, the fourth region 188 can be formed by the superposition of the outer region 156 of the phase shifting structure 150 and the base structure 170. In another embodiment, the fourth region 188 can be defined solely by the base structure 170. In other words, the outer region 156 of the phase shifting structure 150 may not functionally contribute to the resultant loss of height. The fourth region 188 can include a fourth composite aspheric profile.

[0090] In short, by Figure 1A and Figure 2 The basic geometry encompassed by the example optical device 120 and defined by equations (1) to (5) is a combination of a trapezoidal phase shifting structure and a zone refractive surface with an add power effect, which together can improve intermediate vision performance and extend depth of focus while maintaining distance vision. It should be understood that various modifications, enhancements, and adjustments can be made to the optical device 120 described herein without departing from the spirit and scope of the present disclosure.

[0091] Now refer to Figures 3A to 3C , which shows Figure 1A and Figure 2 The surface profile of the front surface 130 of the optic 120 shown in and defined by equations (1) to (5) is graphically represented as graphs 310, 320, and 330 of loss of height versus radial distance from the optical axis 105 of the optic 120. Specifically, Figure 3A The trapezoidal phase shift structure of the optical device 120 is depicted ( Figure 2 310 of the height loss curve of the element 150). Figure 3B Depicts the regional structure of the optical device 120 ( Figure 2 320 of a unitless height loss curve of element 160). Figure 3C A graph 330 depicting the loss of height of the composite multilayer surface profile of the front surface 130 of the optical device 120 is shown. Figures 3A to 3C In all three graphs of , the radius is zero at the optical axis 305. Figure 3C As shown, the height loss curve is essentially parabolic, consistent with the aspheric lens surface. Figures 3A to 3C It is shown for illustration purposes only, ie, to illustrate the shape of the curve, and thus may not be drawn to scale and may not illustrate the position of the curve in terms of specific data points and / or units of measurement.

[0092] Now refer to Figures 4A to 4D , which shows through-focus modulation transfer function (MTF) graphs 410 , 420 , 430 , 440 of four optical devices. Figure 4A A graph 410 of the MTF curve of the optics of a monofocal IOL is shown. Figure 4B An MTF graph 420 is shown for an optical device having a trapezoidal phase shift (TPS) structure (without a zone add power structure). Figure 4C An MTF graph 430 is shown for an optical device having a zone add power structure (and no phase shifting structure). Figure 4D Shown based on Figure 1A and Figure 2 Graph 440 of the MTF of the example optical device 120 of the design shown in FIG and defined by equations (1) to (5). These graphs 410, 420, 430, 440 can be compared and analyzed to further understand the improvements provided by the example optical design (depicted in graph 440) of the present disclosure. For example, Figure 4A As shown, the optics of a monofocal IOL do not have an extended depth of focus. Figure 4B As shown in FIG, an optical device with a trapezoidal phase shift structure (without a zone-additive power structure) has a limited depth of focus range and poor MTF at defocus above 0.5D (near side). Figure 4C As shown, the optical device with the zone add power structure (without the phase shift structure) exhibits bifocality, as evidenced by two distinct peaks at positive and negative focus shifts. This strong bifocality may lead to undesirable pupil-related focus shifts and / or vignetting. Finally, as Figure 4D As shown, based on Figure 1A and Figure 2The exemplary optics of the designs shown and defined by equations (1) to (5) of the present disclosure provide extended intermediate vision without sacrificing distance vision and without more visual impairment than monofocal IOLs. Figure 4D As further shown in , the example optical device further provides enhanced extended depth of focus and MTF performance in intermediate vision, for example, particularly at 1.0D to approximately 1.5D.

[0093] Now refer to Figure 5 , which shows that based on Figure 1A and Figure 2 Graph 500 of simulated monocular visual acuity (VA) for an example optic of the design shown in and defined by equations (1) to (5). Visual acuity (VA) is the primary measure of visual function in both clinical practice and research. VA can be modeled using the intersection of the eye's modulation transfer function (MTF) and the retinal threshold function. Figure 5 In FIG, a solid black curve 510 represents a monofocal IOL, and a plurality of dashed curves 520, 530, 540, 550, 560 represent example optical devices according to the present disclosure. As shown in the graph, each example optical device is associated with a different additional power extension. Figure 5 As shown, each curve of example optics 520, 530, 540, 550, 560 illustrates the depth of focus extension on a monofocal IOL 510. The depth of focus extension ranges from 0.42D in example optic 520 to a maximum depth of focus extension (shown as 570) of 1.38D in example optic 560. While there is a small tradeoff in visual acuity as the depth of focus increases, it will be understood that an optimal design may attempt to balance these considerations.

[0094] In use, the intraocular lenses described herein are adapted to be inserted into a person's eye using conventional surgical techniques modified according to the teachings herein. Typically, the natural lens is first removed, and the IOL can be folded into a compact size to be inserted through an incision or opening in the capsular bag. After insertion, the IOL can be manipulated to assume its proper position in the capsular bag.

[0095] A variety of techniques and materials can be used to manufacture the lenses described in this disclosure. For example, Figure 1A and Figure 1B The optical device 120 can be formed from a variety of biocompatible polymer materials. Some suitable biocompatible materials include, but are not limited to, soft acrylic polymers, hydrogels, polymethacrylates, polysulfones, polystyrene, cellulose, acetate butyrate, or other biocompatible materials. By way of example, in an embodiment, the optical device 120 can be formed from what is commonly referred to as The haptic 110 of the lens can be formed from a suitable biocompatible material as discussed above. While in some cases, the optic 120 and haptic 110 of the IOL can be manufactured as an integral unit, in other cases, they can be formed separately or joined together using techniques known in the art.

[0096] As used herein, "or" is inclusive, not exclusive, unless expressly stated otherwise or the context indicates otherwise. Thus, as used herein, "A or B" means "A, B, or both," unless expressly stated otherwise or the context indicates otherwise. Furthermore, "and" is both conjunctive and plural, unless expressly stated otherwise or the context indicates otherwise. Thus, as used herein, "A and B" means "A and B, jointly or severally," unless expressly stated otherwise or the context indicates otherwise.

[0097] It will be appreciated that the various features and functions disclosed above and others, or alternatives thereto, may be combined as desired into many other different systems or applications. It will also be appreciated that various currently unforeseen or unanticipated alternatives, modifications, variations, or improvements thereto may be subsequently made by those skilled in the art, and such alternatives, variations, and improvements are intended to be covered by the appended claims. It will be appreciated by those skilled in the art that various changes may be made to the above-described embodiments without departing from the scope of the present invention.

Claims

1. An ophthalmic lens comprising: An optical device having a front surface and a back surface arranged about an optical axis, at least one of the front surface and the back surface having a surface profile corresponding to a superposition of at least three profiles, the at least three profiles comprising a phase shifting structure, a domain structure, and a base structure: The phase-shift structure is characterized by an inner region, an outer region, and a transition region, wherein The inner region extends radially from the optical axis to a first boundary; the transition region being disposed between the inner region and the outer region and extending radially from the first boundary to a second boundary, wherein the transition region is adapted such that a phase of radiation incident thereon varies linearly over at least a portion of a radial range between the first boundary and the second boundary to produce a phase shift between the first boundary and the second boundary, the second boundary being disposed at a radial distance farther from the optical axis than the first boundary; and the outer region extending radially from the second boundary toward an outermost edge of the optical device; the areal structure including an inner power zone having a first curvature and an outer transition zone having a second curvature, the inner power zone extending radially from the optical axis to the second boundary, and the outer transition zone extending radially from the optical axis to a third boundary disposed at a greater radial distance from the optical axis than the second boundary; and The base structure has a base curvature extending radially from the optical axis to an outermost edge of the optical device.

2. The ophthalmic lens according to claim 1, wherein The surface profile of at least one of the front surface and the back surface is described by the following equation: WITH total =Z aux +Z zone1 +Z zone2 +Z base in, Z total represents the multi-layer surface profile, Z aux represents the surface profile of the phase-shift structure, Z zone1 represents the surface profile of the inner focal area of ​​the zone structure, Z zone2 The surface contours of the outer transition zones representing the domain structure, and Z base Represents the surface contours of the underlying structure.

3. The ophthalmic lens according to claim 2, wherein: Z aux corresponds to the phase shift structure and is described by the following equation: in, r represents the radial distance from the optical axis of the optical device; r1 represents the radial distance from the optical axis to the first boundary; r2 represents the radial distance from the optical axis to the second boundary; And among them, Δ is defined by the following relationship: in, n1 represents the refractive index of the material forming the optical device, n2 represents the refractive index of the medium surrounding the optical device, λ is the design wavelength, and α represents a non-integer decimal.

4. The ophthalmic lens according to claim 3, wherein: r1 includes values ​​ranging from 0.45 mm to 0.75 mm.

5. The ophthalmic lens according to claim 3, wherein: r2 includes values ​​ranging from 0.75 mm to 1.05 mm.

6. The ophthalmic lens according to claim 2, wherein: Z zone1 corresponds to the inner power region and is described by the following equation: in, r represents the radial distance from the optical axis of the optical device, c1 represents the first curvature of the inner focal power zone, k1 represents the cone constant, r2 represents the radial distance from the optical axis to the second boundary, A4' is the fourth-order aspheric coefficient, and A6' is the sixth-order aspheric coefficient.

7. The ophthalmic lens according to claim 6, wherein: r2 includes values ​​ranging from 0.45 mm to 0.80 mm.

8. The ophthalmic lens according to claim 2, wherein: Z zone2 corresponds to the outer transition region and is described by the following equation: in, r represents the radial distance from the optical axis of the optical device, c2 represents the second curvature of the outer transition zone, k2 represents the cone constant, r2 represents the radial distance from the optical axis to the second boundary, r3 represents the radial distance from the optical axis to the third boundary, A4" is the fourth-order aspheric coefficient, and A6" is the sixth-order aspheric coefficient.

9. The ophthalmic lens according to claim 8, wherein r2 includes values ​​ranging from 0.45 mm to 0.80 mm.

10. The ophthalmic lens according to claim 8, wherein r3 includes values ​​ranging from 0.60 mm to 1.20 mm.

11. The ophthalmic lens according to claim 2, wherein: Z base corresponds to the basic structure and is described by the following equation: in, r represents the radial distance from the optical axis of the optical device, c represents the value of the base curvature, k represents the cone constant, r3 represents the radial distance from the optical axis to the third boundary, A4 is the fourth-order aspheric coefficient, and A6 is the sixth-order aspheric coefficient.

12. The ophthalmic lens according to claim 11, wherein r3 includes values ​​ranging from 0.60 mm to 1.20 mm.

13. The ophthalmic lens of claim 1 , wherein: a first region of the optical device comprising a first composite aspheric profile, the first region being defined as beginning at the optical axis and extending radially to the first boundary; a second region of the optical device comprising a second composite aspheric profile, the second region being defined as beginning at the first boundary and extending radially to the second boundary; a third region of the optical device comprising a third composite aspheric profile, the third region being defined as beginning at the second boundary and extending radially to the third boundary; and A fourth region of the optical device includes a fourth composite aspheric profile, the fourth region being defined from the third boundary to an outermost edge of the optical device.

14. The ophthalmic lens of claim 1, wherein: The inner power zone is configured to provide a depth of focus that enhances intermediate vision performance.

15. The ophthalmic lens according to claim 14, wherein The phase shifting structure is configured to mitigate pupil-related focus shift effects caused by the enhanced depth of focus of the inner focal power region.

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