Animal tissue section staining machine

Abstract

The present application provides an animal tissue section staining machine, including a machine body, a staining chamber is provided in the machine body, a plurality of staining boxes respectively filled with a plurality of different stains are provided at the bottom of the staining chamber, a conveying mechanism for conveying animal tissue sections to the staining box body for staining is provided above the staining box body in the staining chamber, a closing mechanism that can movably cover the staining box body is also provided in the staining chamber, a stain adding mechanism and a stain collecting mechanism connected to the bottom of the staining box body are also provided below the machine body, and a control panel is also provided on the machine body. The present application has a simple structure, and the stain is added to the staining box body by the stain adding mechanism, and the stain in the staining box body is collected by the stain collecting mechanism, so as to realize automatic addition and replacement of the stain, which is practical and convenient; and the staining box body is covered by the closing mechanism when the machine body is not in operation to prevent it from being contaminated and protect the stain.

Description

[Technical field]

[0001] The present application relates to the technical field of experimental equipment, and in particular to an animal tissue section staining machine. [Background technology]

[0002] Tissue sections refer to biological tissues that are processed into thin slices and applied to glass slides for microscope observation. This is an important tool and method in the development of histology and is widely used in biology, medicine (pathology, infectious diseases, etc.), agronomy (plant pathology) and other fields.

[0003] In the process of processing animal tissue sections, the animal tissue sections need to be stained. This process is generally carried out through a staining machine. However, in existing staining machines, the staining agents are added and replaced manually, which is troublesome and inconvenient to operate and easily contaminates the stain. [Summary of the invention]

[0004] The purpose of the present application is to provide a tissue section staining machine that can automatically add and replace stains and protect the stains.

[0005] This application is implemented through the following technical solutions:

[0006] The animal tissue section staining machine comprises a machine body, wherein a staining cavity is arranged in the machine body, and a plurality of staining boxes respectively filled with a plurality of different stains are arranged at the bottom of the staining cavity, wherein a conveying mechanism for conveying animal tissue sections into the staining box for staining is arranged above the staining box in the staining cavity, wherein a cover-closing mechanism capable of movably covering the staining box is also arranged in the staining cavity, wherein a stain adding mechanism and a stain collecting mechanism connected with the bottom of the staining box are also arranged below the machine body, and wherein a control panel electrically connected with the conveying mechanism, the cover-closing mechanism, the stain adding mechanism and the stain collecting mechanism are respectively arranged on one side of the staining cavity on the machine body.

[0007] As described above, the animal tissue section staining machine, the closing mechanism includes a closing group that can cover the staining box body, and a lifting group that can drive the closing group to move up and down, the lifting group includes a rotating roller that is rotatably arranged in the staining chamber, and a plurality of winding ropes connected between the closing group and the rotating roller, the rotating roller rotates to roll up or release the winding rope, thereby driving the closing group to rise or fall.

[0008] As described above, the animal tissue section staining machine, the dye adding mechanism includes a plurality of dye tanks arranged below the machine body and corresponding to the dyeing box body, and a delivery pipe connected between the dye tank and the dyeing box body, and the delivery pipe is also provided with a delivery pump for delivering the dye in the dye tank to the dyeing box body.

[0009] As described above, the animal tissue section staining machine, the stain collecting mechanism includes a collecting channel arranged below the machine body and located directly below the staining box body, and a collecting box connected to one end of the collecting channel, and the other end of the collecting channel is provided with a cleaning component for cleaning the collecting channel.

[0010] As described above, the animal tissue section staining machine, the cleaning component includes a water tank, and a water pipe connected between one end of the collecting channel and the water tank, and the water pipe is also provided with a water pump for conveying clean water in the water tank to the collecting channel for flushing.

[0011] In the animal tissue section staining machine as described above, the bottom surface of the collecting channel is inclined from the cleaning component toward the collecting box.

[0012] As described above, the animal tissue section staining machine is also provided with a drawer which is slidably provided on the machine body, and the drawer is pulled out to put the animal tissue sections into the staining box body.

[0013] As described above, the animal tissue section staining machine, the staining box body is also provided with a staining rack for placing animal tissue sections.

[0014] The animal tissue section staining machine as described above, wherein the transport mechanism comprises:

[0015] A transporting member, used for driving the dyeing rack to move;

[0016] A first moving group, used for driving the transport member to move along the z-axis direction, and the transport member is arranged on the first moving group;

[0017] The second moving mechanism is used for driving the transport member to move along the XY plane, and the first moving group is arranged on the second moving mechanism.

[0018] As described above, in the animal tissue section staining machine, the machine body is hingedly provided with a transparent observation plate for rotatably covering the staining chamber.

[0019] Compared with the prior art, the present application has the following advantages: the present application has a simple structure, and the operation of each mechanism is controlled separately through a control panel. Dye is added to the dyeing box body through a dye adding mechanism, and the dye in the dyeing box body is collected through a dye collecting mechanism, thereby realizing automatic addition and replacement of dye, which is practical and convenient; and the dyeing box body is covered by a closing mechanism when the machine body is not running to reduce the contact between the dye and the external environment, avoid contamination, and protect the dye.

Brief Description of the Drawings

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0021] Figure 1 This is one of the structural schematic diagrams of the animal tissue section staining machine according to the embodiment of the present application.

[0022] Figure 2 This is the second structural schematic diagram of the animal tissue section staining machine according to the embodiment of the present application (when the transparent observation plate is flipped open).

[0023] Figure 3 This is the third structural schematic diagram of the animal tissue section staining machine according to the embodiment of the present application (when staining is being performed).

[0024] Figure 4 This is the fourth structural schematic diagram of the animal tissue section staining machine according to the embodiment of the present application (when the drawer is opened).

[0025] Figure 5 This is the fifth structural schematic diagram of the animal tissue section staining machine according to the embodiment of the present application.

[0026] Figure 6 It is a partial cross-sectional schematic diagram of the dye collecting mechanism according to an embodiment of the present application. [Specific implementation method]

[0027] In order to make the technical problems, technical solutions and beneficial effects solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0028] like Figures 1 to 6 As shown, the embodiment of the present application proposes an animal tissue section staining machine, including a body 1, a staining chamber 11 is provided in the body 1, and a plurality of staining box bodies 12 respectively filled with a plurality of different stains are provided at the bottom of the staining chamber 11, and a conveying mechanism 2 for conveying animal tissue sections to the staining box body 12 for staining is provided above the staining box body 12 in the staining chamber 11, and a closing mechanism 3 capable of movably covering the staining box body 12 is also provided in the staining chamber 11, and a stain adding mechanism 4 and a stain collecting mechanism 5 connected to the bottom of the staining box body 12 are also provided below the body 1, and a control panel 6 electrically connected to the conveying mechanism 2, the closing mechanism 3, the stain adding mechanism 4 and the stain collecting mechanism 5 are respectively provided on one side of the staining chamber 11 on the body 1.

[0029] The operation of each mechanism is controlled by the control panel 6. The dye is added to the dye box body 12 by the dye adding mechanism 4, and the dye in the dye box body 12 is collected by the dye collecting mechanism 5, so that automatic addition and replacement of the dye is realized, which is practical and convenient. And the dye box body 12 is covered by the cover mechanism 3 when the machine body 1 is not running to reduce the contact between the dye and the external environment, avoid it from being contaminated, and protect the dye.

[0030] Specifically, the plurality of dyeing boxes 12 form two rows and are arranged side by side at the bottom of the dyeing chamber 11 .

[0031] Furthermore, the cover closing mechanism 3 includes a cover closing group 31 capable of covering the dyeing box body 12, and a lifting group capable of driving the cover closing group 31 to move up and down, and the lifting group includes a rotating roller 32 rotatably arranged in the dyeing chamber 11, and a plurality of winding ropes 33 connected between the cover closing group 31 and the rotating roller 32. The rotating roller rotates to roll up or release the winding rope, thereby driving the cover closing group to rise or fall.

[0032] Furthermore, the dye adding mechanism 4 includes a plurality of dye tanks 41 disposed below the machine body 1 and correspondingly disposed with the dyeing box body 12, and a delivery pipe 42 connected between the dye tank 41 and the dyeing box body 12, and the delivery pipe 42 is also provided with a delivery pump 43 for delivering the dye in the dye tank 41 to the dyeing box body 12.

[0033] Specifically, the plurality of dye tanks 41 are respectively filled with a plurality of different dyes. When adding, the delivery pump 43 is started to extract the dye in the dye tank 41 and deliver it to the dyeing box 12, thereby realizing automatic addition of dye, which is convenient and quick, and avoids the risk of contaminating the dye during manual addition.

[0034] Furthermore, the dye collecting mechanism 5 includes a collecting channel 51 disposed below the machine body 1 and directly below the dyeing box body 12, and a collecting box 52 connected to one end of the collecting channel 51, and a cleaning component 53 for cleaning the collecting channel 51 is disposed at the other end of the collecting channel 51. A collecting port for connecting the bottom of the dyeing box body 12 and the collecting channel 51 is also provided at the bottom of the machine body 1.

[0035] Specifically, the cleaning component 53 includes a water tank 531 and a water pipe 532 connected between one end of the collecting channel 51 and the water tank 531. The water pipe 532 is also provided with a water pump 533 for transporting clean water in the water tank 531 to the collecting channel 51 for flushing.

[0036] In this embodiment, the bottom surface of the collecting channel 51 is inclined from the cleaning component 53 toward the collecting box 52 .

[0037] During collection, the dye in the dyeing box body 12 is discharged into the collecting channel 51 through the collecting port, and then flows into the collecting box 52 for collection. Then the water pump 533 is started to pump out the clean water in the water tank 531 and transport it to the collecting channel 51 for flushing, thereby realizing automatic collection of the dye.

[0038] Furthermore, a drawer 13 is slidably provided on the machine body 1 , and the drawer 13 is pulled out to put the animal tissue sections into the staining box body 12 .

[0039] Specifically, the staining box body 12 is also provided with a staining rack 7 for placing animal tissue sections.

[0040] Furthermore, the transport mechanism 2 comprises:

[0041] The transporting member 21 is used to drive the dyeing frame 7 to move;

[0042] A first moving group 22 is used to drive the transport member 21 to move along the z-axis direction, and the transport member 21 is arranged on the first moving group 22;

[0043] The second moving mechanism 23 is used for driving the transporting member 21 to move along the XY plane. The first moving group 22 is disposed on the second moving mechanism 23 .

[0044] During staining, the drawer 13 is pulled out, and the animal tissue sections are placed in the staining rack 7. Then, the first moving group 22 and the second moving mechanism 23 cooperate to operate simultaneously, driving the transport member 21 to move and drive the staining rack 7 to move to the corresponding staining box 12 for staining.

[0045] Furthermore, a transparent observation panel 14 is hingedly provided on the machine body 1 and is used for rotatably covering the dyeing chamber 11. The dyeing condition in the machine body 1 can be observed in real time through the transparent observation panel 14.

[0046] To better understand the technical solution of this embodiment, its working principle is described as follows:

[0047] During staining, the drawer 13 is pulled out, and the animal tissue sections are placed in the staining rack 7. Then, the first moving group 22 and the second moving mechanism 23 cooperate to operate simultaneously, driving the transport member 21 to move and drive the staining rack 7 to move to the corresponding staining box 12 for staining.

[0048] When adding dye, the delivery pump 43 is started to extract the dye in the dye tank 41 and deliver it to the dye box 12, so as to realize automatic addition of dye, which is convenient and fast, and avoids the risk of contaminating the dye during manual addition.

[0049] When replacing the dye, the dye in the dyeing box body 12 is discharged into the collecting channel 51 through the collecting port, and then flows into the collecting box 52 for collection. Then the water pump 533 is started to pump out the clean water in the water tank 531 and transport it to the collecting channel 51 for flushing, thereby realizing automatic collection of the dye. Then the delivery pump 43 is started to pump out the dye in the dye tank 41 and transport it to the dyeing box body 12, thereby realizing automatic addition of dye, which is convenient and quick, and avoids the risk of contaminating the dye during manual addition.

[0050] It should be understood that the terms "first", "second", etc. are used in this application to describe various information, but this information should not be limited to these terms, and these terms are only used to distinguish the same type of information from each other. For example, without departing from the scope of this application, the "first" information may also be referred to as the "second" information, and similarly, the "second" information may also be referred to as the "first" information. In addition, the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0051] As described above, one or more implementation methods are provided in combination with specific contents, and the specific implementation of this application is not limited to these descriptions. Any similarity or similarity with the method, structure, etc. of this application, or some technical deductions or replacements made based on the concept of this application should be considered as the protection scope of this application.

Claims

1. Animal tissue section staining machine, characterized in that, The invention comprises a machine body (1), wherein a dyeing chamber (11) is provided in the machine body (1), and a plurality of dyeing boxes (12) each containing a plurality of different dyes are provided at the bottom of the dyeing chamber (11); a transport mechanism (2) for transporting animal tissue sections to the dyeing box (12) for dyeing is provided above the dyeing box (12) in the dyeing chamber (11); a cover closing mechanism (3) capable of movably covering the dyeing box (12) is provided in the dyeing chamber (11); a dye adding mechanism (4) and a dye collecting mechanism (5) connected to the bottom of the dyeing box (12) are provided below the machine body (1); and a control panel (6) electrically connected to the transport mechanism (2), the cover closing mechanism (3), the dye adding mechanism (4) and the dye collecting mechanism (5) is provided on one side of the dyeing chamber (11) on the machine body (1); The cover closing mechanism (3) comprises a cover closing group (31) capable of covering the dyeing box body (12), and a lifting group capable of driving the cover closing group (31) to move up and down, the lifting group comprising a rotating roller (32) rotatably arranged in the dyeing chamber (11), and a plurality of winding ropes (33) connected between the cover closing group (31) and the rotating roller (32); The dye adding mechanism (4) comprises a plurality of dye tanks (41) arranged below the machine body (1) and correspondingly arranged with the dye box body (12), and a delivery pipe (42) communicating between the dye tanks (41) and the dye box body (12), wherein the delivery pipe (42) is further provided with a delivery pump (43) for delivering the dye in the dye tanks (41) to the dye box body (12); The dye collecting mechanism (5) comprises a collecting channel (51) disposed below the machine body (1) and directly below the dyeing box body (12), and a collecting box (52) connected to one end of the collecting channel (51); a cleaning component (53) for cleaning the collecting channel (51) is disposed at the other end of the collecting channel (51); The cleaning assembly (53) comprises a water tank (531), and a water delivery pipe (532) connected between one end of the collecting channel (51) and the water tank (531); the water delivery pipe (532) is also provided with a water pump (533) for delivering clean water in the water tank (531) to the collecting channel (51) for flushing; The bottom surface of the collecting channel (51) is arranged to be inclined from the cleaning component (53) toward the collecting box (52); The staining box body (12) is also provided with a staining rack (7) for placing animal tissue sections; The transport mechanism (2) comprises: A transport member (21) for driving the dyeing frame (7) to move; The first moving group (22) is used to drive the transport member (21) to move along the z-axis direction, and the transport member (21) is arranged on the first moving group (22); the second moving mechanism (23) is used to drive the transport member (21) to move along the XY plane, and the first moving group (22) is arranged on the second moving mechanism (23).

2. The animal tissue section staining machine according to claim 1, characterized in that: The machine body (1) is also provided with a drawer (13) which is slidably mounted thereon. The drawer (13) is pulled out to place animal tissue sections into the staining box body (12).

3. The animal tissue section staining machine according to claim 1, characterized in that: A transparent observation plate (14) is hingedly provided on the machine body (1) and is used for rotatably covering the dyeing chamber (11).

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