A blood sampling device for capillary peripheral blood

Abstract

This invention relates to the field of medical device technology, specifically to a blood collection device for capillary blood, comprising: an upper shell, a microneedle ejection assembly, and a base. The upper shell is fastened to the base, and a folded rubber sleeve is disposed between the upper shell and the base. The microneedle ejection assembly includes a top pusher, a guide shell, and a bottom microneedle disc. A vacuum spring is disposed between the pusher and the base. The pusher is placed inside the folded rubber sleeve and compresses the folded rubber sleeve. An opening for the microneedle disc to enter and exit is provided at the bottom of the base, and a sealing sticker is provided on the base with an opening corresponding to the opening. An air hole is provided on the base, and a one-way valve retainer is disposed at the position of the corresponding air hole. A one-way valve core is embedded in the one-way valve retainer, and a one-way valve spring is disposed between the one-way valve core and the one-way valve retainer. The one-way valve core abuts against the air hole. This invention uses microneedles to pierce the skin epidermis, and by pressing the upper shell, a vacuum is generated within the blood collection device to draw out capillary blood and store it in a test tube.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to a capillary peripheral blood sampling device. Background Art

[0002] Blood testing is an important in vitro diagnostic test item. Common blood collection methods include collecting capillary peripheral blood and collecting venous blood. Capillary peripheral blood is usually collected from the fingertips, and the blood collection volume is small, usually only 0.1 to 0.5 ml. It is suitable for testing blood sugar, blood routine, blood type and other items that do not require much blood volume; venous blood is generally drawn from the elbow, and the collection volume is mostly a few milliliters. It can be used for biochemical tests such as liver and kidney function, tumor indicators, and hormone levels. Due to the complexity of venous blood collection, it can usually only be performed by professional medical personnel. It is difficult for ordinary people to collect blood by themselves; at the same time, collecting venous blood is painful, which makes the person whose blood is collected feel uncomfortable.

[0003] The usual steps for venous blood collection are to locally puncture the skin and disinfect it with iodine, then puncture the blood vessel with the needle of a syringe. After success, draw the corresponding venous blood for testing. After the puncture is completed and the needle is removed, you must use a cotton swab or cotton ball to press the puncture needle site hard to prevent further bleeding.

[0004] International application WO 2014 / 169433 A1 discloses a vacuum blood collection device, which needs to be performed by professionals because it requires a needle to be inserted into a vein.

[0005] Korean patent KR101195974B1 discloses a microneedle for blood collection, the diameter of which is about 100um, which can effectively reduce the pain of the person whose blood is collected. The microneedle has a fine tube in the middle, which is difficult to process.

[0006] International application WO2019 / 033362A1 discloses a blood sampling device and its control device. Using a microneedle array, the microneedles invade the skin tissue of the person being sampled, and then the blood in the capillaries is extracted through a vacuum pump, which can achieve painless collection of a certain amount of blood. The device uses a microneedle array with internal through holes, which is difficult to process; at the same time, the overall device requires a vacuum pump, control circuit, etc., and the system is complex. Summary of the invention

[0007] In order to solve the technical problems of complex structure, difficult processing and complicated blood collection process of blood collection devices in the prior art, an embodiment of the present invention provides a capillary peripheral blood blood collection device, the blood collection device comprising: an upper shell, a microneedle ejection assembly and a base,

[0008] The upper shell is buckled on the base, and a folding rubber sleeve is arranged between the upper shell and the base; the microneedle ejection assembly includes a top pusher, a guide protective shell and a bottom microneedle plate,

[0009] A vacuum spring is arranged between the pusher and the base, the pusher is placed in the folding rubber sleeve and squeezes the folding rubber sleeve; an opening for the microneedle disk to enter and exit is arranged at the bottom of the base, and a sealing sticker is arranged on the base, and the sealing sticker has an opening corresponding to the opening;

[0010] When the upper shell is pressed, the microneedle ejection assembly responds to the upper shell and pushes the microneedle disk out of the opening; when the upper shell is released, the microneedle ejection assembly responds to the vacuum spring and retracts the microneedle disk into the opening;

[0011] An air hole is provided on the base, and a one-way valve retaining ring is provided corresponding to the position of the air hole, a one-way valve core is embedded in the one-way valve retaining ring, a one-way valve spring is provided between the one-way valve core and the one-way valve retaining ring, and the one-way valve core abuts against the air hole;

[0012] When the upper shell is pressed, the gas inside the blood collection device squeezes the one-way valve core, and the gas inside the blood collection device is discharged from the air hole. When the upper shell is released, the one-way valve core responds to the one-way valve spring to block the air hole.

[0013] In a preferred embodiment, the pushing member includes a pushing sheet, the base is provided with a stepped platform, and the vacuum spring is placed between the pushing sheet and the stepped platform.

[0014] In a preferred embodiment, a blood collecting groove is provided in the base, a test tube interface is provided on the side wall of the base, the blood collecting groove is connected to the test tube interface, and the test tube interface is connected to the test tube.

[0015] In a preferred embodiment, the guide housing is embedded with a slider and an ejection rod.

[0016] A card block is arranged inside the guide housing, a return spring is arranged between the card block and the slider, a ejection spring is arranged between the bottom of the ejection rod and the slider, and the ejection spring is placed inside the return spring; a push ring is arranged at the lower side of the push member, and the push ring abuts against the upper side of the slider;

[0017] The slider includes an extrusion head and a first clamping head; spring sheets are arranged on both sides of the guide housing, the top of the spring sheet has an extrusion sheet extending to the outside of the guide housing, and a second clamping head is arranged inside the spring sheet; the ejection rod includes a first hook and a second hook, the first hook is clamped with the first clamping head, and the second hook is clamped with the second clamping head;

[0018] The microneedle disk is installed at the bottom of the ejection rod, and the base is provided with a limiting portion for limiting the guide protective shell.

[0019] In a preferred embodiment, a third hook is arranged on the outer side of the guide shield, a slide groove of the third hook is arranged on the lower side of the push member, a third clamping head is formed on the lower side of the slide groove, and the third hook is clamped with the third clamping head.

[0020] In a preferred embodiment, a fourth hook is disposed on the outer side of the extrusion head, a fourth clamping head is disposed at a position of the guide shield facing the spring sheet, and the fourth hook is clamped with the fourth clamping head.

[0021] In a preferred embodiment, a first guide rail is further provided on the outer side of the guide protective shell, a first guide groove is provided in the base, and the first guide rail is embedded in the first guide groove to slide.

[0022] In a preferred embodiment, a second guide groove is further provided on the lower side of the pusher, and a second guide rail is further provided on the outer side of the guide housing, and the second guide rail is embedded in the second guide groove to slide;

[0023] The ejection rod is further provided with a third guide rail, and the slide block is further provided with a third guide groove, and the third guide rail is embedded in the third guide groove and slides;

[0024] The sliding block is further provided with a fourth guide rail, and the inner side of the guide shield is further provided with a fourth guide groove, and the fourth guide rail is embedded in the fourth guide groove for sliding.

[0025] In a preferred embodiment, an upper shell hook is disposed on the inner side of the upper shell, a base clamp is disposed on the outer side of the base, and the upper shell hook is clamped with the base clamp.

[0026] In a preferred embodiment, the upper shell is provided with a scrap buckle, and the scrap buckle is configured to be folded toward the inside of the upper shell and abut against the edge of the base.

[0027] The beneficial effects brought about by the technical solution provided by the embodiment of the present invention include at least:

[0028] The present invention proposes a capillary peripheral blood sampling device, in which a sealing patch is attached to the skin surface, a microneedle is used to pierce the skin epidermis, and a vacuum is generated in the blood sampling device by pressing the upper shell, so that the peripheral blood in the capillaries is sucked out and stored in a test tube. There is no need for professional medical personnel to collect blood, and ordinary people can collect capillary peripheral blood by themselves, and the blood collection amount is comparable to that of conventional venous blood collection.

[0029] The present invention provides a capillary peripheral blood sampling device. The microneedle ejection component adopts the method of ejecting a microneedle disk. The microneedle penetrates the skin epidermis, and a vacuum is generated in the blood sampling device to suck out the peripheral blood in the capillary, thereby avoiding the pain caused by excessive human operation of the microneedle piercing the skin.

[0030] The present invention provides a capillary peripheral blood sampling device, which reduces pain by precisely adjusting the length and diameter of microneedles, and the microneedle wound is small and easy to heal. The microneedles are solid needles, which are easy to process.

[0031] The present invention proposes a capillary peripheral blood sampling device, in which a microneedle can be ejected multiple times. If the amount of blood sucked out in a single time is insufficient, the blood can be repeatedly pressed and sucked. If the amount of blood collected at a single blood sampling position is insufficient, the position can be changed and the skin can be pierced with a microneedle to collect blood again. The required amount of blood can be achieved by repeatedly pressing the upper shell.

[0032] The present invention provides a capillary peripheral blood sampling device. After the blood sampling is completed, the microneedle can be locked by a scrap buckle to avoid accidental touch causing the microneedle to pop out and cause damage and pollution. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0034] Figure 1 It is a schematic diagram of one side of the base of a capillary peripheral blood sampling device of the present invention.

[0035] Figure 2 It is a schematic diagram of the upper shell side of a capillary peripheral blood sampling device of the present invention.

[0036] Figure 3 It is an exploded view of a capillary peripheral blood sampling device of the present invention.

[0037] Figure 4 It is an exploded view of the microneedle ejection assembly of the present invention.

[0038] Figure 5 The present invention is a schematic diagram of the internal structure of a base of a capillary peripheral blood sampling device.

[0039] Figure 6 The present invention is a schematic diagram of a guide shield of a microneedle ejection assembly of a capillary peripheral blood sampling device.

[0040] Figure 7 The present invention is a capillary peripheral blood sampling device. Figure 6 Section view in the AA direction.

[0041] Figure 8 The present invention is a capillary peripheral blood sampling device. Figure 6 Section view along the BB direction.

[0042] Fig. 9 The present invention is a capillary peripheral blood sampling device in which the microneedle is not ejected during the pressing process of the upper shell. Figure 6 Section view in the AA direction.

[0043] Fig.10 The present invention is a capillary peripheral blood sampling device in which the microneedle is not ejected during the pressing process of the upper shell. Figure 6 Section view along the BB direction.

[0044] Fig.11 The present invention is a capillary peripheral blood sampling device in which the microneedle is in the pop-up state during the pressing process of the upper shell. Figure 6 Section view in the AA direction.

[0045] Fig.12 The present invention is a capillary peripheral blood sampling device in which the microneedle is in the pop-up state during the pressing process of the upper shell. Figure 6 Section view along the BB direction.

[0046] Fig.13 The present invention is a cross-sectional view of the position of the air hole opened on the base of a capillary peripheral blood sampling device.

[0047] Fig.14 The present invention is a schematic diagram of a locking process of a discarded buckle of a capillary peripheral blood sampling device. DETAILED DESCRIPTION

[0048] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0049] The terms "first", "second", "third", "fourth", etc. (if any) in the specification and claims of the present invention and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged where appropriate, so that the embodiments of the present invention described herein can, for example, be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0050] like Figure 1 The schematic diagram of the base side of a capillary peripheral blood sampling device of the present invention is shown. Figure 2 The schematic diagram of the upper shell side of a capillary peripheral blood sampling device of the present invention is shown. Figure 3 The exploded view of a capillary peripheral blood sampling device of the present invention is shown. According to an embodiment of the present invention, a capillary peripheral blood sampling device includes an upper shell 1, a folding rubber sleeve 2, a microneedle ejection assembly 3, a vacuum spring 4 and a base 5, and the upper shell 1 is buckled on the base 5.

[0051] According to the embodiment of the present invention, an upper shell hook 102 is provided on the inner side of the upper shell 1 , and a base clamp 501 is provided on the outer side of the base 5 . The upper shell hook 102 is clamped with the base clamp 501 to limit the upper shell 1 .

[0052] In a preferred embodiment, the upper shell 1 is provided with a scrap buckle 101 , which is configured to be folded toward the inside of the upper shell 1 and abut against the edge of the base 5 to limit the upper shell 1 .

[0053] A foldable rubber sleeve 2 is provided between the upper shell 1 and the base 5 , and the foldable rubber sleeve 2 is bonded to the edge of the base 5 , and the bonding method includes but is not limited to gluing, ultrasonic welding, laser welding and the like.

[0054] The microneedle ejection assembly 3 is installed in the base 5 in a slidable manner relative to the base 5, and the top of the microneedle ejection assembly 3 is placed in the folding rubber sleeve 2. The vacuum spring 4 is arranged between the top of the microneedle ejection assembly 3 and the base 5, and is sleeved on the outside of the microneedle ejection assembly 3.

[0055] like Figure 4 The exploded view of the microneedle ejection assembly of the present invention is shown in FIG. Figure 5 The schematic diagram of the internal structure of the base of a capillary peripheral blood sampling device of the present invention is shown. According to an embodiment of the present invention, the microneedle ejection assembly 3 includes a pusher 301 at the top, a guide shield 308 and a microneedle plate 319 at the bottom. The guide shield 308 is embedded with a slider 303 and an ejection rod 315. The microneedle plate 319 is installed at the bottom of the ejection rod 315, and a microneedle 321 is arranged at the bottom of the microneedle plate 319, and the microneedle 321 is a solid needle.

[0056] According to an embodiment of the present invention, a vacuum spring 4 is arranged between the pushing member 301 and the base 5 . Specifically, the pushing member 301 includes a pushing sheet 322 , the base 5 is provided with a stepped platform 506 , and the vacuum spring 4 is placed between the pushing sheet 322 and the stepped platform 506 .

[0057] According to an embodiment of the present invention, the pusher 301 is placed in the folding rubber sleeve 2 and presses the folding rubber sleeve 2, and the top of the folding rubber sleeve 2 abuts against the upper shell 1. When the upper shell 1 is pressed, the upper shell 1 presses the folding rubber sleeve 2 and presses the pusher 301 to move downward.

[0058] Combination Figure 1 , Figure 2 , Figure 3 and Figure 5 The bottom of the base 5 is provided with an opening 508 for the microneedle disk 319 to enter and exit, and a sealing sticker 10 is provided on the base 5, and the sealing sticker 10 is provided with an opening corresponding to the opening 508. The opening of the sealing sticker 10 is used to penetrate or retract the microneedles 321 at the bottom of the microneedle disk 319.

[0059] A blood collecting groove 504 is provided in the base 5, a test tube interface 502 is provided on the side wall of the base 5, the blood collecting groove 504 is connected to the test tube interface 502, and the test tube interface 502 is connected to the test tube 6. In a preferred embodiment, the test tube 6 is provided with a test tube cover 601.

[0060] like Figure 6 The schematic diagram of the guide shield of the microneedle ejection assembly of the capillary peripheral blood sampling device of the present invention is shown. Figure 7 The capillary peripheral blood sampling device of the present invention is Figure 6 Section view in the AA direction, Figure 8 The capillary peripheral blood sampling device of the present invention is Figure 6 Section view in the BB direction, combined with Figures 1 to 8 According to an embodiment of the present invention, a block 323 is disposed in the guide housing 308, a return spring 307 is disposed between the block 323 and the slider 303, a ejection spring 314 is disposed between the bottom of the ejection rod 315 and the slider 303, and the ejection spring 314 is disposed in the return spring 307. A push ring 329 is disposed at the lower side of the push member 301, and the push ring 329 abuts against the upper side of the slider 303.

[0061] According to an embodiment of the present invention, the slider 303 includes an extrusion head 327 and a first clamp 304. Shrapnel 313 is arranged on both sides of the guide housing 308, and the top of the shrapnel 313 has an extrusion sheet 328 extending to the outside of the guide housing 308, and a second clamp 324 is arranged inside the shrapnel 313, and the shrapnel 313 is made of elastic material. The extrusion head 327 is directly opposite to the extrusion sheet 328. When the slider 303 moves downward until the extrusion head 327 contacts the extrusion sheet 328, the extrusion head 327 pushes the extrusion sheet 328 to fold the shrapnel 313 to the outside of the guide housing 308.

[0062] The ejection rod 315 includes a first hook 316 and a second hook 318 . The first hook 316 is located at the top of the ejection rod 315 and is engaged with the first clamp 304 . The second hook 318 is located at the bottom of the ejection rod 315 and is engaged with the second clamp 324 .

[0063] A microneedle plate 319 is installed at the bottom of the ejection rod 315. In a specific embodiment, a microneedle plate hook 320 is provided on the upper side of the microneedle plate 319, and the microneedle plate hook 320 is connected to the bottom of the ejection rod 315 to install the microneedle plate 319 at the bottom of the ejection rod 315. A plurality of microneedles 321 are provided at the bottom of the microneedle plate 319, and the microneedles 321 are solid needles. A limiting portion 507 is provided on the base 5 for limiting the guide housing 308.

[0064] According to an embodiment of the present invention, a third hook 310 is arranged on the outer side of the guide shield 308, a slide groove 302 for accommodating the third hook 310 is arranged on the lower side of the push member 301, a third clamping head 3021 is formed on the lower side of the slide groove 302, and the third hook slides in the slide groove 302 and is clamped with the third clamping head 3021.

[0065] A fourth hook 306 is disposed outside the extrusion head 327 , a fourth clamping head 325 is disposed at a position of the guide shield 308 directly opposite to the spring piece 313 , and the fourth hook 306 is clamped with the fourth clamping head 325 .

[0066] According to the embodiment of the present invention, a first guide rail 312 is further provided on the outer side of the guide housing 308, a first guide groove 503 is provided in the base 5, and the first guide rail 312 is embedded in the first guide groove 503 to slide. A second guide groove 330 is further provided on the lower side of the pusher 301, and a second guide rail 311 is further provided on the outer side of the guide housing 308, and the second guide rail 311 is embedded in the second guide groove 330 to slide.

[0067] The ejection rod 315 is also provided with a third guide rail 317, and the slider 303 is also provided with a third guide groove 326, and the third guide rail 317 is embedded in the third guide groove 326 for sliding. The slider 303 is also provided with a fourth guide rail 305, and the inner side of the guide shield 308 is also provided with a fourth guide groove 309, and the fourth guide rail 305 is embedded in the fourth guide groove 309 for sliding.

[0068] According to an embodiment of the present invention, when the upper shell 1 is pressed, the microneedle ejection assembly 3 responds to the upper shell 1 and pushes the microneedle disk 319 out of the opening 508, and the microneedles 321 at the bottom of the microneedle disk 319 pass through the opening corresponding to the sealing patch 10 and the opening 508, and puncture the skin for blood collection. When the upper shell 1 is released, the microneedle ejection assembly 3 responds to the vacuum spring 4 and retracts the microneedle disk 319 into the opening 508, thereby driving the microneedles 321 to retract into the opening corresponding to the sealing patch 10 and the opening 508. The specific blood collection process is described in detail below.

[0069] According to an embodiment of the present invention, an air hole 505 is opened on the base 5, and a one-way valve retaining ring 9 is arranged corresponding to the position of the air hole 505, a one-way valve core 7 is embedded in the one-way valve retaining ring 9, a one-way valve spring 8 is arranged between the one-way valve core 7 and the one-way valve retaining ring 9, and the one-way valve core 7 is abutted against the air hole 505.

[0070] When the upper shell 1 is pressed, the internal air pressure of the blood sampling device squeezes the one-way valve core 7 to move toward the one-way valve retaining ring 9, and the internal air of the blood sampling device is discharged from the air hole 505. When the upper shell 1 is released, the one-way valve core 7 responds to the one-way valve spring 8 to block the air hole 505. The process of forming vacuum air pressure inside the blood sampling device is described in detail below.

[0071] Combine the following Figures 1 to 14 The use process of the capillary peripheral blood sampling device of the present invention is described.

[0072] (1)Default state.

[0073] like Figure 7 and Figure 8 As shown, a capillary peripheral blood sampling device provided by the present invention is in a default state (ie, the upper shell 1 is not pressed).

[0074] In the default state, the vacuum spring 4 pushes the push piece 322 of the push member 301, the push piece 322 pushes the folding rubber sleeve 2, and the folding rubber sleeve 2 pushes the upper shell 1. The upper shell 1, the folding rubber sleeve 2 and the push piece 322 are in an extruded state, and the upper shell hook 102 is engaged with the base clamp 501 to limit the upper shell 1.

[0075] The third clamping head 3021 on the lower side of the sliding groove 302 of the pushing member 301 clamps the third clamping hook 310 to lift the guide shield 308. The slider 303 is lifted up under the elastic force of the return spring 307.

[0076] The first clamping head 304 of the slider 303 clamps the first hook 316 of the ejection rod 315 to lift the ejection rod 315. The ejection rod 315 lifts the microneedle disk 319 through the microneedle disk hook 320.

[0077] (2) The upper shell is pressed down.

[0078] like Fig. 9 The capillary peripheral blood sampling device of the present invention is shown in the state where the microneedle is not ejected during the pressing process of the upper shell. Figure 6 Section view in the AA direction, Fig.10 The capillary peripheral blood sampling device of the present invention is shown in the state where the microneedle is not ejected during the pressing process of the upper shell. Figure 6 In the cross-sectional view along the BB direction, the upper shell 1 of the capillary peripheral blood sampling device provided by the present invention is pressed down (the microneedle 321 is not ejected).

[0079] When using the capillary peripheral blood sampling device provided by the present invention, the sealing sticker 10 is attached to the arm or other skin, with the test tube 6 facing downward. After the sealing sticker 10 is in close contact with the skin, the opening corresponding to the opening 508 of the sealing sticker 10 is blocked, and due to the sealing bonding of the folded rubber sleeve 2 and the base 5, a closed cavity is formed inside the blood sampling device.

[0080] The upper shell 1 is pressed, and the upper shell 1 pushes the folding rubber sleeve 2, and the folding rubber sleeve 2 pushes the pushing piece 322 of the pushing member 301, and the pushing ring 329 of the pushing member 301 pushes the slider 303. The pushing piece 322 squeezes the vacuum spring 4, and the slider 303 squeezes the return spring 307 and the ejection spring 314.

[0081] Under the elastic force of the return spring 307 , the block 323 in the guide housing 308 is pushed, thereby pushing the guide housing 308 to move downward until the lower part of the guide housing 308 contacts the limiting part 507 of the base 5 , and the limiting part 507 limits the guide housing 308 .

[0082] The upper shell 1 is continuously pressed, and the upper shell 1 pushes the folding rubber sleeve 2, and the folding rubber sleeve 2 pushes the pushing piece 322 of the pushing member 301, and the pushing ring 329 of the pushing member 301 pushes the slider 303. The pushing piece 322 continues to squeeze the vacuum spring 4. At this time, since the guide protective shell 308 is limited, the pushing member 301 moves downward relative to the guide protective shell 308, and the third hook 310 on the outer side of the guide protective shell 308 is separated from the third clamping head 3021 of the pushing member 301 and slides into the slide groove 302.

[0083] The slider 303 squeezes the return spring 307 and the ejection spring 314, and the return spring 307 and the ejection spring 314 are further compressed to store elastic potential energy. Since the second hook 318 of the ejection rod 315 is supported by the second clamp 324 inside the spring sheet 313, the microneedle disk 319 will not be ejected.

[0084] (3) Microneedle pops out.

[0085] like Fig.11 The capillary peripheral blood sampling device of the present invention is shown in the state where the microneedle pops out during the pressing process of the upper shell. Figure 6 Section view in the AA direction, Fig.12 The capillary peripheral blood sampling device of the present invention is shown in the state where the microneedle pops out during the pressing process of the upper shell. Figure 6 In the cross-sectional view along the BB direction, a microneedle 321 of a capillary peripheral blood sampling device provided by the present invention is ejected.

[0086] The upper shell 1 is continuously pressed, and the upper shell 1 pushes the folding rubber sleeve 2, and the folding rubber sleeve 2 pushes the pushing piece 322 of the pushing member 301, and the pushing ring 329 of the pushing member 301 pushes the slider 303. When the slider 303 moves downward until the extrusion head 327 contacts the extrusion sheet 328, the extrusion head 327 pushes the extrusion sheet 328 to fold the spring sheet 313 toward the outside of the guide housing 308, and the spring sheet 313 is stretched open, and the ejection rod 315 is released.

[0087] The ejection spring 314 between the bottom of the ejection rod 315 and the slider 303 pushes the ejection rod 315 to eject, and the ejection rod 315 ejects until the first hook 316 engages with the first clamping head 304 of the slider 303, and the ejection rod 315 is limited by the slider 303. At the same time, the ejection rod 315 drives the microneedle plate 319 to eject the opening 508 of the base 5, and the microneedles 321 exceed the plane of the sealing patch 10, pass through the opening corresponding to the opening 508 of the sealing patch 10, and penetrate into the skin, and the return spring 307 still remains in a compressed state.

[0088] (4) Loosen the upper cover and create a vacuum.

[0089] like Fig.13 The cross-sectional view of the position of the pores opened on the base of a capillary peripheral blood sampling device of the present invention is shown. According to an embodiment of the present invention, after the sealing sticker 10 is in close contact with the skin, the openings corresponding to the sealing sticker 10 and the opening 508 are blocked, forming a closed cavity inside the blood sampling device.

[0090] According to the embodiment of the present invention, the base 5 is provided with an air hole 505, and a one-way valve retaining ring 9 is provided corresponding to the position of the air hole 505, a one-way valve core 7 is embedded in the one-way valve retaining ring 9, a one-way valve spring 8 is provided between the one-way valve core 7 and the one-way valve retaining ring 9, and the one-way valve core 7 abuts against the air hole 505. Under normal conditions, the one-way valve retaining ring 9 is screwed into the base 5, pressing the one-way valve spring 8, and the one-way valve spring 8 presses the one-way valve core 7 to seal the air hole 505.

[0091] When the upper shell 1 is pressed, the volume inside the blood sampling device decreases and the air pressure increases. When the pressure difference with the outside air is greater than the elastic force generated by the one-way valve spring 8, the gas in the blood sampling device is discharged through the air hole 505.

[0092] Loosen the upper shell 1, the vacuum spring 4 pushes the pushing piece 322 of the pushing member 301, the pushing piece 322 pushes the folding rubber sleeve 2, and the folding rubber sleeve 2 pushes the upper shell 1 to move upward until the upper shell hook 102 of the upper shell 1 is engaged by the base clamping head 501 of the base 5, limiting the upper shell 1 and generating a vacuum in the blood collection device.

[0093] During the ascending process of the pushing member 301, the slider 303 moves upward under the action of the return spring 307, and the first clamping head 304 of the slider 303 clamps the first hook 316 of the ejection rod 315, driving the ejection rod 315 and the microneedle disk 319 to move upward, and the second hook 318 of the ejection rod 315 opens the spring sheet 313 and returns to the top of the spring sheet 313, and clamps with the second clamping head 324 on the inner side of the spring sheet 313.

[0094] During the rising process of the pushing member 301, the pushing member 301 moves upward relative to the guide protective shell 308. When the third hook 310 on the outside of the guide protective shell 308 is engaged with the third clamping head 3021 of the pushing member 301, the third clamping head 3021 of the pushing member 301 drives the third hook 310 to move upward, causing the guide protective shell 308 to move upward until the lower part of the guide protective shell 308 is separated from the limiting part 507 of the base 5.

[0095] After the upper shell 1 is loosened, the one-way valve spring 8 pushes the one-way valve core 7, so that the one-way valve core 7 blocks the air hole 505, and the vacuum spring 4 returns the upper shell 1, the micro needle 321 returns, and a vacuum is generated in the blood collection device. The blood in the capillaries is vacuumed out, and the blood flows into the test tube 6 along the blood collecting groove 504 in the base 5 through the test tube interface 502.

[0096] like Fig.14 The schematic diagram of the locking process of the discarded buckle of a capillary peripheral blood sampling device of the present invention is shown. According to an embodiment of the present invention, the upper shell 1 is provided with a discarded buckle 101, which is configured to be folded toward the inside of the upper shell 1 and abut against the edge of the base 5 to limit the upper shell 1.

[0097] After the blood collection is completed, the blood collection device is removed from the skin. The discarded buckle 101 is pressed to cause plastic deformation, folded toward the inside of the upper shell 1, and the upper shell 1 and the base 5 are locked, so that the upper shell 1 cannot be pressed down, preventing the microneedle 321 from popping out again.

[0098] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A capillary peripheral blood sampling device, characterized in that: The blood collection device comprises: an upper shell, a microneedle ejection assembly and a base. The upper shell is buckled on the base, and a folding rubber sleeve is arranged between the upper shell and the base; the microneedle ejection assembly includes a top pusher, a guide protective shell and a bottom microneedle plate, A vacuum spring is arranged between the pusher and the base, the pusher is placed in the folding rubber sleeve and squeezes the folding rubber sleeve; an opening for the microneedle disk to enter and exit is arranged at the bottom of the base, and a sealing sticker is arranged on the base, and the sealing sticker has an opening corresponding to the opening; When the upper shell is pressed, the microneedle ejection assembly responds to the upper shell and pushes the microneedle disk out of the opening; when the upper shell is released, the microneedle ejection assembly responds to the vacuum spring and retracts the microneedle disk into the opening; An air hole is provided on the base, and a one-way valve retaining ring is arranged at a position corresponding to the air hole, a one-way valve core is embedded in the one-way valve retaining ring, a one-way valve spring is arranged between the one-way valve core and the one-way valve retaining ring, and the one-way valve core abuts against the air hole; When the upper shell is pressed, the gas inside the blood collection device squeezes the one-way valve core, and the gas inside the blood collection device is discharged from the air hole. When the upper shell is released, the one-way valve core responds to the one-way valve spring to block the air hole. The pushing member includes a pushing sheet, the base is provided with a stepped platform, and the vacuum spring is placed between the pushing sheet and the stepped platform; A blood collecting groove is arranged in the base, a test tube interface is arranged on the side wall of the base, the blood collecting groove is connected to the test tube interface, and the test tube interface is connected to the test tube; The guide housing is embedded with a slide block and an ejection rod. A card block is arranged inside the guide housing, a return spring is arranged between the card block and the slider, a ejection spring is arranged between the bottom of the ejection rod and the slider, and the ejection spring is placed inside the return spring; a push ring is arranged at the lower side of the push member, and the push ring abuts against the upper side of the slider; The slider includes an extrusion head and a first clamping head; spring sheets are arranged on both sides of the guide housing, the top of the spring sheet has an extrusion sheet extending to the outside of the guide housing, and a second clamping head is arranged inside the spring sheet; the ejection rod includes a first hook and a second hook, the first hook is clamped with the first clamping head, and the second hook is clamped with the second clamping head; The microneedle disk is installed at the bottom of the ejection rod, and the base is provided with a limiting part for limiting the position of the guide protective shell; A third hook is arranged on the outer side of the guide housing, a slide groove of the third hook is arranged on the lower side of the pusher, a third clamping head is formed on the lower side of the slide groove, and the third hook is clamped with the third clamping head; A fourth hook is arranged outside the extrusion head, a fourth clamping head is arranged at a position of the guide shield facing the spring sheet, and the fourth hook is clamped with the fourth clamping head.

2. The blood collection device according to claim 1, characterized in that: A first guide rail is further arranged on the outer side of the guide protective shell, a first guide groove is arranged in the base, and the first guide rail is embedded in the first guide groove for sliding.

3. The blood collection device according to claim 1, characterized in that: A second guide groove is further provided on the lower side of the pusher, and a second guide rail is further provided on the outer side of the guide housing, and the second guide rail is embedded in the second guide groove and slides; The ejection rod is further provided with a third guide rail, and the slide block is further provided with a third guide groove, and the third guide rail is embedded in the third guide groove and slides; The sliding block is further provided with a fourth guide rail, and the inner side of the guide shield is further provided with a fourth guide groove, and the fourth guide rail is embedded in the fourth guide groove for sliding.

4. The blood collection device according to claim 1, characterized in that: An upper shell hook is arranged on the inner side of the upper shell, and a base clamping head is arranged on the outer side of the base, and the upper shell hook is clamped with the base clamping head.

5. The blood collection device according to claim 1, characterized in that: The upper shell is provided with a scrap buckle, and the scrap buckle is configured to be folded toward the inside of the upper shell and abut against the edge of the base.

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