Textiles and medical devices using the same

Abstract

The title of the present invention is "Textiles and Medical Devices Using the Same". Disclosed herein are textiles that include: a) a first yarn including one or more filaments, the filaments including a first polymer; b) one or more other yarns having a composition and / or properties different from the first yarn; wherein the first yarn exhibits a higher elasticity than the one or more other yarns, the textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility, and wherein the textile is configured to be inserted and / or implanted into the body of a subject. Also described herein are medical devices having the disclosed textiles. In addition, a method of manufacturing the disclosed textiles is disclosed.

Description

[0001] Cross - reference to related applications

[0002] This application claims the benefit of U.S. Provisional Application No. 63 / 241,330, filed on September 7, 2021, the entire content of which is incorporated herein by reference. Technical Field

[0003] This application relates to aspects of textile materials including yarns having different elasticities. This application also relates to aspects of implantable medical devices including such textile materials. Background Art

[0004] Depending on the nature and type of the medical device, many medical devices often incorporate textiles and fabrics that can achieve various functions. These textiles can be used in a variety of applications, from delivery devices, sutures, wound dressings, implanted valves, skin grafts to arterial grafts, etc.

[0005] For example, implantable bioprosthetic heart valves and stent grafts often include fabric layers, such as an outer covering attached to a metal frame or stent or an inner or outer fabric skirt. In the case of a bioprosthetic heart valve, the fabric skirt can be used to anchor the valve leaflets to the stent. The fabric skirt can also serve to protect the delicate valve leaflets from damage that might otherwise occur when the heart valve is radially compressed for delivery through the patient's vasculature.

[0006] The fabrics present in such exemplary devices need to possess various properties, such as, for example, a desired level of stretchability to allow the fabric to conform to the valve shape and / or changes in its dimensions as it expands from a collapsed configuration. Similarly, the textiles and fabrics need to have shape adaptability to conform to the body's natural anatomy and allow prevention of blood leakage, etc., after insertion.

[0007] While stretchable textiles and fabrics including various elastomeric fibers are very popular in the manufacture of comfortable clothing, shapewear, sportswear, etc., these conventional textiles are not readily suitable for medical use when the textiles come into contact with an object's body and / or body fluids. Thus, the textiles need to have other properties to be compatible with the object's body and not cause harm in any way.

[0008] This disclosure at least partially meets these needs and others. Summary of the Invention

[0009] Certain aspects of the present disclosure relate to textiles. Certain aspects relate to textiles that include: a) a first yarn including one or more filaments, the filaments including a first polymer; b) one or more other yarns including a composition and / or properties different from the first yarn; wherein the first yarn exhibits higher elasticity than the one or more other yarns, the textile exhibits an ultimate elongation of about 50% to about 700% and has shape - adapting and biocompatibility, and wherein the textile is configured to be inserted and / or implanted into the body of an object.

[0010] In still other aspects, the first polymer may include thermoplastic polyurethane (TPU), polyurethane (PU), thermoplastic elastomer (TPE), and elastic polyolefin, polybutylene terephthalate (PBT), silicone - based elastomer, or a combination thereof.

[0011] In certain aspects, the first yarn may be a monofilament. In other aspects, the first yarn may be a multifilament.

[0012] In still other aspects, the one or more other yarns may include fully drawn yarn, spun - drawn yarn, low - twist or non - twist yarn, twisted yarn, flat yarn, textured yarn, high - stretch (HS) textured yarn, high - bulk textured yarn, high - shrinkage yarn, or any combination thereof.

[0013] In still other aspects, the one or more other yarns include polyolefin, polyester, polyurethane, thermoplastic polyurethane, polyamide, or a combination thereof.

[0014] In addition, or alternatively, aspects are also disclosed in which the textile further includes a second yarn, the second yarn including one or more filaments, the filaments including a second polymer. In such aspects, the second yarn is different from the first yarn. In still other aspects, the second yarn may coat the first yarn to form a multi - component yarn such that the first yarn forms a core and the second yarn forms a sheath. In still other aspects, the first polymer has higher elasticity than the second polymer. In still other aspects, the second polymer may include polyester, nylon, polyolefin, or a combination thereof.

[0015] In still other aspects, the textiles disclosed herein may have a knitted, woven, or braided structure.

[0016] Articles are also disclosed herein that include any of the textiles disclosed herein.

[0017] In some aspects, an implantable prosthetic valve is disclosed, which includes: an annular frame having an inflow end, an outflow end, and a longitudinal axis, wherein the annular frame is configured to expand and contract; and a sealing element fixed to the frame, wherein the sealing element includes a textile, and the textile includes: a) a first yarn including one or more filaments, and the filaments include a first polymer; b) one or more other yarns having a composition and / or properties different from those of the first yarn; wherein the first yarn exhibits higher elasticity than the one or more other yarns, the textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility, and wherein the textile is configured to be inserted and / or implanted into a subject's body.

[0018] In still other aspects, a medical device is disclosed herein, which includes any of the textiles disclosed herein.

[0019] Furthermore, in some aspects, a method is disclosed herein, which includes forming a textile, and the textile includes: a) a first yarn including one or more filaments, and the filaments include a first polymer; b) one or more other yarns having a composition and / or properties different from those of the first yarn; and c) optionally a second yarn including one or more filaments, and the filaments include a second polymer, wherein if the second yarn is present, the second yarn coats the first yarn to form a multi-component yarn such that the first yarn forms a core and the second yarn forms a sheath, wherein the first yarn exhibits higher elasticity than the one or more other yarns and, if the second yarn is present, the elasticity of the second yarn; and wherein the textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility and is configured to be inserted and / or implanted into a subject's body.

[0020] In some aspects, the forming step includes weaving, knitting, braiding, or any combination thereof.

[0021] Other aspects of the present disclosure will be set forth in part in the detailed description, the drawings, and the appended claims, and will in part be derived from the detailed description or can be learned through the practice of the present disclosure. It should be understood that the foregoing general description and the following detailed description are both exemplary and explanatory only and are not limiting of the disclosed disclosure. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figures 1A - 1B An exemplary monofilament multi-component yarn in one aspect is shown: Figure 1A Depicts a single-covered multi-component yarn in which a monofilament first yarn is covered by a monofilament second yarn, while Figure 1B Depicts a double-covered multi-component yarn in which a monofilament first yarn is covered by two layers of monofilament second yarns.

[0023] Figures 2A - 2B Shows exemplary multi-component yarns in one aspect: Figure 2A Depicts a single-covered multi-component yarn in which a monofilament first yarn is covered by a multifilament second yarn, Figure 2B Depicts a double-covered multi-component yarn in which a monofilament first yarn is covered by two layers of multifilament second yarn.

[0024] Figures 3A - 3B Shows exemplary multi-component yarns in one aspect: Figure 3A Depicts a single-covered multi-component yarn in which a multifilament first yarn is covered by a multifilament second yarn, while Figure 3B Depicts a double-covered multi-component yarn in which a multifilament first yarn is covered by two layers of multifilament second yarn.

[0025] Figure 4 Shows an exemplary woven pattern of an exemplary textile in one aspect.

[0026] Figures 5A - 5D Shows exemplary knitting patterns of an exemplary textile in one aspect: Figure 5A Depicts an exemplary simple single jersey knit construction; Figure 5B Depicts an exemplary single jersey knit with a knit-miss pattern construction (photo of the construction on the left; schematic diagram of the construction on the right); Figure 5C Depicts an exemplary single jersey knit with a knit-tuck pattern construction; Figure 5D Depicts an exemplary plaited knit-tuck textile construction in one aspect.

[0027] Figure 6 Shows a perspective view of an exemplary implantable medical device such as a prosthetic heart valve, which includes an exemplary aspect of an exemplary textile used as a paravalvular leak seal.

[0028] Figure 7 Shows a perspective view showing an exemplary implantable medical device such as a prosthetic heart valve, which includes another aspect of a paravalvular leak seal, including an exemplary textile used as a paravalvular leak seal. Detailed Description

[0029] The present disclosure can be more readily understood by reference to the following specific embodiments, examples, drawings, and claims, as well as their prior and subsequent descriptions. However, before disclosing and describing the articles, systems, and / or methods of the present disclosure, it should be understood that the present disclosure is not limited to the specific or exemplary aspects of the disclosed articles, systems, and / or methods, which can of course vary. It should also be understood that the terms used herein are for the purpose of describing particular aspects only and are not intended to be limiting.

[0030] The following description of the present disclosure is provided as an implementation of the teachings of the present disclosure in its best, currently known aspects. To this end, those skilled in the relevant art will recognize and understand that various changes can be made to the various aspects of the present disclosure described herein while still obtaining the beneficial results of the present disclosure. It will also be apparent that some of the desired benefits of the present disclosure can be obtained by selecting some features of the present disclosure without utilizing other features. Therefore, those of ordinary skill in the relevant art will recognize that various modifications and adaptations to the present disclosure are possible and, in some cases, even desirable and become part of the present disclosure. Accordingly, the following description is again provided to illustrate the principles of the present disclosure rather than to limit it.

[0031] Definitions

[0032] As used in this application and the claims, unless the context clearly dictates otherwise, the singular forms "a", "an", and "the" include plural forms. Thus, for example, reference to "yarn" includes aspects having two or more such yarns unless the context clearly indicates otherwise.

[0033] It should also be understood that the terms used herein are for the purpose of describing particular aspects only and are not intended to be limiting. As used in the specification and claims, the term "comprising" can include aspects of "consisting of" and "consisting essentially of". In addition, the term "includes" means "comprises".

[0034] For the terms "such as", "exemplary", and "for example" and their grammatical equivalents, unless otherwise clearly indicated, it should be understood that the phrase "and without limitation" follows thereafter.

[0035] Ranges can be expressed herein as from "about" one particular value and / or to "about" another particular value. When expressing such a range, another aspect includes from one particular value and / or to another particular value. Similarly, when a value is expressed as an approximation, by use of the antecedent "about", it will be understood that the particular value forms another aspect. It should be further understood that each endpoint of a range is significant with respect to the other endpoint and independent of the other endpoint.

[0036] As used herein, the term "optional" or "optionally" means that the subsequent described event or circumstance may or may not occur, and this description includes both the case where the event or circumstance occurs and the case where it does not occur.

[0037] It should be understood that when an element is referred to as being "connected" or "coupled" to another element, it can be directly connected or coupled to the other element, or there may be intervening elements. In contrast, when an element is referred to as being "directly connected" or "directly coupled" to another element, there are no intervening elements. Other words used to describe the relationship between various elements or layers should be interpreted in a similar manner (e.g., "between" versus "immediately between", "adjacent" versus "immediately adjacent", "on" versus "immediately on").

[0038] It will be understood that although the terms "first", "second", etc. may be used herein to describe various elements, components, regions, layers, and / or sections, these elements, components, regions, layers, and / or sections should not be limited by these terms. These terms are only used to distinguish one element, component, region, layer, or section from another element, component, region, layer, or section. Thus, without departing from the teachings of the exemplary embodiments, the first element, component, region, layer, or section discussed below may be referred to as the second element, component, region, layer, or section.

[0039] Spatially relative terms such as "below", "beneath", "under", "above", "over", etc. may be used herein for ease of description to describe the relationship of one element or feature to another element(s) or feature(s). It will be understood that, in addition to the orientation depicted in the figures, spatially relative terms are intended to encompass different orientations of the device during use or operation. For example, if the device in the figures is flipped, an element described as "below" or "beneath" another element or feature will be oriented "above" that other element or feature. Thus, the term "below" can encompass both the orientation of "above" and "below". The device may be oriented in other ways (rotated 90 degrees or at other orientations), and the spatially relative descriptors used herein are to be interpreted accordingly.

[0040] As used herein, the term "substantially" means that the subsequent described event or circumstance occurs completely or the subsequent described event or circumstance generally, typically, or approximately occurs.

[0041] In addition, the term "substantially" in certain aspects may refer to at least about 80%, at least about 85%, at least about 90%, at least about 91%, at least about 92%, at least about 93%, at least about 94%, at least about 95%, at least about 96%, at least about 97%, at least about 98%, at least about 99%, or about 100% of the stated property, component, composition, or other condition that is substantially used to characterize or otherwise quantify a quantity.

[0042] As used herein, the term "substantially" in contexts such as "substantially the same" or "substantially similar" refers to a method, system, or component that is at least about 90%, at least about 91%, at least about 92%, at least about 93%, at least about 94%, at least about 95%, at least about 96%, at least about 97%, at least about 98%, at least about 99%, or about 100% similar to the method, system, or component with which it is being compared.

[0043] As used herein, the term "substantially the same reference composition", or "substantially the same reference article" or "substantially the same reference method" refers to a reference composition or article or method that contains substantially the same components or steps and does not contain the inventive components or steps. In another exemplary aspect, the term "substantially" in contexts such as "substantially the same reference composition" refers to a reference composition that contains substantially the same components and in which the inventive components are replaced by components common in the art.

[0044] As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0045] As used herein, the term or phrase "effective", "effective amount", or "conditions effective for..." refers to an amount or condition that is capable of performing a function or property, and the effective amount or condition is expressed with respect to that function or property. As will be pointed out below, the exact amount or specific conditions required will vary by aspect, depending on recognized variables such as the materials employed and the processing conditions observed. Thus, it is not always possible to specify an exact "effective amount" or "conditions effective for...". However, it should be understood that an appropriate effective amount will be readily determined by one of ordinary skill in the art using only routine experimentation.

[0046] As used herein, the term "fiber" includes fibers of extreme or infinite length (i.e., filaments) and fibers of short length (i.e., staple fibers).

[0047] As used herein, the term "polymer" refers to a molecule containing multiple monomer units (e.g., 2 to 5 to 10 to 25 to 50 to 100 to 250 to 500 to 1000 or more copies). The polymers disclosed herein can have various structures, e.g., and without limitation, cyclic, branched, and hyperbranched structures. Hyperbranched structures include star structures (e.g., configurations where three or more chains emanate from a single pivot point), comb structures (e.g., structures having a main chain and multiple side chains), and dendrimeric structures (such as dendritic and hyperbranched polymers), among others.

[0048] As used herein, the term "homopolymer" refers to a polymer containing multiple copies of one monomer unit. The term "copolymer" refers to a polymer containing multiple copies of at least two different monomer units, examples of which include random, gradient, periodic (e.g., alternating), and block copolymers. As used herein, the term "block copolymer" refers to a copolymer containing two or more compositionally distinct polymer blocks, e.g., monomers present in one polymer block may not be present in another polymer block. As used herein, the term "polymer block" is a group of monomer units (e.g., 2 to 5 to 10 to 25 to 50 to 100 to 250 to 500 to 1000 or more units). The blocks can be branched or unbranched. The blocks can contain a single type of monomer unit (also referred to herein as a "homopolymeric block"), or they can contain multiple types of monomer units (also referred to herein as a "copolymeric block"), which can be provided, for example, in a random, gradient, or periodic (e.g., alternating) distribution.

[0049] As used herein, the term "polyester" refers to a class of polymers containing ester functional groups in the main chain. The polyesters disclosed herein include naturally occurring chemicals, such as those in plant cutin, as well as synthetic compounds prepared by step-growth polymerization. In certain examples, polyesters include polyethylene terephthalate (PET) homopolymers and copolymers, polypropylene terephthalate (PPT) homopolymers and copolymers, and polybutylene terephthalate (PBT) homopolymers and copolymers, among others, including homopolymers and copolymers containing comonomers such as cyclohexanedimethanol, cyclohexanedicarboxylic acid, isophthalic acid, etc.

[0050] As used herein, the term "polyamide" is defined as any long-chain polymer in which the linking functional group is an amide (-CO-NH-) bond. The term polyamide is further defined to include copolymers, terpolymers, etc., as well as homopolymers, and blends of two or more polyamides. In some aspects, the plurality of polyamide fibers includes one or more of nylon 6, nylon 66, nylon 10, nylon 612, nylon 12, nylon 11, or any combination thereof. In other aspects, the plurality of polyamide fibers includes nylon 6 or nylon 66. In still other aspects, the plurality of polyamide fibers is nylon 6. In still other aspects, the plurality of polyamide fibers is nylon 66.

[0051] As defined herein, the term "polyolefin" refers to any class of polymers produced from simple olefins (also known as olefins having the general formula C n H 2n ). In some aspects, polyolefins include, but are not limited to, polyethylene, polypropylene, homopolymers and copolymers, poly(l-butene), poly(3-methyl-l-butene), poly(4-methyl-1-pentene), etc., as well as combinations or mixtures of two or more of the foregoing.

[0052] As defined herein, the term "polyurethane" refers to any class of polymers composed of chains of organic units linked by urethane (urethane, R 1 -O-CO-NR 2 -R 3 , where R1, R2, and R3 are the same or different).

[0053] As defined herein, the term "polyether" refers to any class of polymers composed of chains of organic units linked by ether groups.

[0054] As defined herein, the term "polyurea" refers to any class of polymers in which the optional monomer units of isocyanates and amines react with each other to form urea bonds.

[0055] As defined herein, the term "polystyrene" refers to any class of synthetic polymers produced from simple styrene as a monomer. It should be understood that the term "polystyrene" includes atactic and syndiotactic polystyrene. In certain specific aspects, copolystyrenes are also described, including high-impact polystyrene (HIPS), acrylonitrile-butadiene-styrene (ABS), or copolymers of styrene and acrylonitrile (SAN), or copolymers of styrene and maleic acid (SMA).

[0056] Throughout this disclosure, various aspects of the present invention may be presented in a range format. It should be understood that the description of the range format is merely for convenience and brevity and should not be construed as a rigid limitation on the scope of the present invention. Accordingly, the description of a range should be considered to have specifically disclosed all the possible sub-ranges and individual numerical values within that range. For example, the description of a range such as 1 to 6 should be considered to have specifically disclosed sub-ranges such as 1 to 3, 1 to 4, 1 to 5, 2 to 4, 2 to 6, 3 to 6, etc. and the individual numbers within that range, such as 1, 2, 2.7, 3, 4, 5, 5.3, 6, and any whole and partial increments therebetween. This applies regardless of the width of the range.

[0057] Although, for the sake of presentation, the operations of the exemplary aspects of the disclosed methods may be described in a particular sequential order, it should be understood that the disclosed aspects may encompass an order of operations other than the particular sequential order disclosed. For example, in some cases, the operations described in sequence may be rearranged or performed simultaneously. Additionally, the description and disclosure provided in connection with one particular aspect are not limited to that aspect and may be applicable to any of the disclosed aspects.

[0058] Furthermore, for simplicity, the drawings may not show the various ways in which the disclosed systems, methods, and devices may be used in combination with other systems, methods, and devices (which would be readily discernible by one of ordinary skill in the art based on this disclosure). Additionally, the description sometimes uses terms such as "generate" and "provide" to describe the disclosed methods. These terms are high-level abstract expressions of the actual operations that can be performed. The actual operations corresponding to these terms may vary according to a particular implementation and are readily discernible by one of ordinary skill in the art based on this disclosure.

[0059] Textiles

[0060] Textiles are disclosed herein that include: a) a first yarn including one or more filaments, the filaments including a first polymer; b) one or more other yarns having a composition and / or properties different from the first yarn. In still other aspects, the first yarn present herein has a higher elasticity than the one or more other yarns. In still other aspects, the textile may exhibit an ultimate elongation of from about 50% to about 700%, including exemplary values of about 100%, about 150%, about 200%, about 250%, about 300%, about 350%, about 400%, about 450%, about 500%, about 550%, about 600%, and about 650%.

[0061] In still other aspects, the textile has shape adaptability and biocompatibility. And in still other aspects, the fabric is configured to be inserted and / or implanted into the body of an object.

[0062] It should be understood that the first yarn and the one or more other yarns are also biocompatible. In still other aspects, the first yarn and the one or more other yarns are medical grade yarns.

[0063] In still other aspects, the first yarn is an elastomeric yarn. In such aspects, the first polymer includes an elastomer. In still other aspects, the first polymer may include thermoplastic polyurethane (TPU), polyurethane (PU), thermoplastic elastomer (TPE), and elastomeric polyolefin, polybutylene terephthalate (PBT), silicone-based elastomer, or a combination thereof. In still other aspects, the first polymer is thermoplastic polyurethane (TPU). In other aspects, the first polymer is polyurethane (PU). In still other aspects, the first polymer is thermoplastic elastomer (TPE). In still other aspects, the first polymer is elastomeric polyolefin. In still other non-limiting aspects, the first polymer is polybutylene terephthalate (PBT). In still other aspects, the first polymer is silicone-based elastomer.

[0064] In still other aspects, the hardness of the first polymer can be from about 75A to about 75D, including exemplary values of about 80A, about 85A, about 90A, about 95A, about 100A, about 20D, about 25D, about 30D, about 35D, about 40D, about 45D, about 50D, about 55D, about 60D, about 65D, and about 70D. In still other aspects, the first polymer can have a hardness value between any two of the foregoing values.

[0065] In still other aspects, the ultimate tensile strength of the first polymer can be between about 4500 psi and about 8000 psi, including exemplary values of about 5000 psi, about 5500 psi, about 6000 psi, about 6500 psi, about 7000 psi, and about 7500 psi. In still other aspects, the first polymer can have an ultimate tensile strength between any two of the foregoing values.

[0066] In still other aspects, the ultimate elongation of the first polymer can be between about 50% and about 700%, including exemplary values of about 100%, about 150%, about 200%, about 250%, about 300%, about 350%, about 400%, about 450%, about 500%, about 550%, about 600%, and about 650%. In still other aspects, the first polymer can have an ultimate elongation value between any two of the foregoing values.

[0067] In some aspects, the first yarn can be a monofilament. However, in still other aspects, the first yarn can be a multifilament. In aspects where the first yarn is a multifilament, such an exemplary yarn can have any desired filament count suitable for a particular application. For example, and without limitation, the filament count of the first yarn can be greater than about 1 to about 50, including exemplary values of about 2, about 3, about 5, about 7, about 10, about 12, about 15, about 17, about 20, about 12, about 25, about 27, about 30, about 32, about 35, about 37, about 40, about 42, about 45, and about 47. It should also be understood that if a particular application requires, the filament count can be greater than about 50, greater than about 80, or even greater than about 100.

[0068] In still other aspects, the fineness (size) of one or more filaments of the first yarn ranges from about 5 denier to about 1000 denier, including exemplary values of about 10 denier, about 20 denier, about 50 denier, about 100 denier, about 200 denier, about 300 denier, about 400 denier, about 500 denier, about 600 denier, about 700 denier, about 800 denier, and about 900 denier. Again, it should be understood that the particular monofilament fineness can be determined based on the desired application.

[0069] In still other aspects, one or more filaments of the first yarn can be produced by any method known in the art and suitable for the desired application. For example, and without limitation, one or more filaments of the first yarn can be melt-spun.

[0070] In still other aspects, if there is more than one other yarn in the textile articles disclosed herein, such other yarns can be the same or different. It should be understood that such other yarns can have the same or different compositions, or be of the same or different types.

[0071] In still other aspects, the one or more other yarns include polyolefins, polyesters, polyurethanes, thermoplastic polyurethanes, polyamides, or combinations thereof. It should be understood that in such aspects, polyesters can include polyethylene terephthalate (PET) homopolymers and copolymers, polytrimethylene terephthalate (PPT) homopolymers and copolymers, and polybutylene terephthalate (PBT) homopolymers and copolymers, etc., including homopolymers and copolymers containing comonomers such as cyclohexanedimethanol, cyclohexanedicarboxylic acid, isophthalic acid, etc. In still other aspects, polyolefins can include ultra-high molecular weight polyethylene, low molecular weight polyethylene, polypropylene, polytetrafluoroethylene, expanded polytetrafluoroethylene, and polyvinylidene fluoride. In still other aspects, polyamides can include nylon 6, nylon 66, nylon 666, nylon 610, nylon 512, nylon 11 or nylon 12, or combinations thereof. In still other aspects, the one or more other yarns can further include polyethers, polyureas, their copolymers, or combinations thereof.

[0072] In some aspects, the one or more other yarns may include fully drawn yarns, spin-drawn yarns, low-twist or non-twisted yarns, twisted yarns, flat yarns, textured yarns, high-stretch (HS) textured yarns, high-bulk textured yarns, high-shrinkage yarns, or any combination thereof.

[0073] In some aspects, the one or more other yarns may also include composite fibers. It should be understood that, as used herein, composite fibers refer to fibers that may include one or more different materials. In some aspects, the composite fibers are bicomponent fibers, which may have any configuration, such as, by way of example and not limitation, a side-by-side configuration, a core-sheath configuration, a segmented configuration, an islands-in-the-sea configuration, or any combination thereof.

[0074] It should be understood that the one or more other yarns have less stretchability and elasticity than the first yarn. In still other aspects, the one or more other yarns may be substantially rigid. In yet still other aspects, the one or more other yarns may be substantially semi-rigid.

[0075] In still other aspects, the textile may further include a second yarn. In such aspects, the second yarn may include one or more filaments that include a second polymer. In still other aspects, the first polymer in the first yarn has higher elasticity than the second polymer in the second yarn. In still other aspects, the second polymer may include polyester, nylon, polyolefin, or a combination thereof. For example, and by way of example and not limitation, the second polymer may include polyethylene terephthalate (PET) homopolymers and copolymers, polypropylene terephthalate (PPT) homopolymers and copolymers, and polybutylene terephthalate (PBT) homopolymers and copolymers, among others. In still other aspects, the second polymer may include ultra-high molecular weight polyethylene, low molecular weight polyethylene, polypropylene, polytetrafluoroethylene, expanded polytetrafluoroethylene, polyvinylidene fluoride. In still other aspects, the second polymer may include nylon 6, nylon 66, nylon 666, nylon 610, nylon 512, nylon 11 or nylon 12, or a combination thereof. In still other aspects, the second yarn may be the same as or different from the one or more other yarns.

[0076] In still other aspects, a second yarn can be wrapped around a first yarn to form a multi-component yarn. In such exemplary and non-limiting aspects, the first yarn can form a core while the second yarn can form a sheath. In certain aspects, the second yarn can be a monofilament. And in still other aspects, the second yarn can be a multifilament. In aspects where the second yarn is a multifilament, the filament count of such a yarn can be greater than 1 to about 150, including exemplary values of about 2, about 5, about 7, about 10, about 15, about 20, about 25, about 30, about 35, about 40, about 45, about 50, about 55, about 60, about 65, about 70, about 75, about 80, about 85, about 90, about 95, about 100, about 105, about 110, about 115, about 120, about 125, about 130, about 135, about 140, and about 145. It should also be understood, however, that the filament count can be greater than about 150, greater than about 200, or even greater than about 300 (if desired) if a particular application so requires.

[0077] In still other aspects, the fineness of one or more filaments of the second yarn ranges from about 5 denier to about 1000 denier, including exemplary values of about 10 denier, about 20 denier, about 50 denier, about 100 denier, about 200 denier, about 300 denier, about 400 denier, about 500 denier, about 600 denier, about 700 denier, about 800 denier, and about 900 denier. Again, it will be understood that the particular monofilament fineness can be determined based on the desired application.

[0078] In still other aspects, the multi-component yarn can be single-wrapped or double-wrapped. In such exemplary and non-limiting aspects, if the multi-component yarn is double-wrapped, two second yarns wrap the first yarn in opposite directions.

[0079] In still other aspects, the second yarn can be of any type. For example, and without limitation, the second yarn can include fully drawn yarn, spin-drawn yarn, low-twist or non-twist yarn, twisted yarn, flat yarn, textured yarn, high-stretch (HS) textured yarn, high-bulk textured yarn, high-shrinkage yarn, or any combination thereof.

[0080] Some exemplary multi-component yarns are shown in Figures 1A - 3B . For example, Figure 1A shows a monofilament first yarn 102 wrapped by a monofilament second yarn 104. It also shows the start of a double-wrap of the second yarn. Figure 1B More detailed schematic views of double-wraps are shown in

[0081] Figure 2A An exemplary schematic view of a single-covered multi-component yarn including a monofilament first yarn 102 and a multifilament second yarn 108 is similarly shown. Figure 2B A double covering of the monofilament first yarn 102 with the multifilament yarns 108 and 110 wound in opposite directions is shown.

[0082] Figure 3A A single-covered multifilament first yarn 112 with a multifilament second yarn 114 is shown. Figure 3B A double covering of the multifilament first yarn 112 with the multifilament yarns 114 and 116 wound in opposite directions is shown.

[0083] In still other aspects, the textiles disclosed herein can have any desired construction. In some aspects, the textiles can have a knitted, woven, or braided construction.

[0084] In such aspects, if the textile is knitted, such textile can include a simple single-sided jersey knit construction; a single-sided jersey knit with a weave-float pattern construction; a single-sided jersey knit with a weave-tuck pattern construction; a tricot knit, a locknit, a satin knit, a reveres locknit, a sharkskin knit, a purl knit, a rib stitch knit, an interlock stitch knit, a double knit, a warp knit, a raschel knit cableknit, a bird’s eye knit, a pontell knit, an intarsia knit, a jacquard knit, a knitted terry textile, a knitted velour textile, a sliver knit, a fleece knit, or any combination thereof. In still other aspects, the textiles can have a warp knitting, weft knitting, or crocheted construction. Additionally, the weft yarn can include a first yarn that can or cannot be covered.

[0085] Some exemplary constructions are shown in Figures 5A - 5D For example, as Figure 5AAs shown, the textile can have a simple single-sided jersey knit construction. In such an exemplary aspect, a multi-component yarn 202 including a first yarn (e.g., TPU) as the core and a second yarn (e.g., PET) as the sheath is knitted with one or more other yarns 204 (e.g., fine flat or twisted multifilament yarns) in a "plaiting arrangement". In these exemplary aspects, the flat or twisted yarn can be from about 10 denier to about 200 denier, including exemplary values of about 20 denier, about 50 denier, about 70 denier, about 100 denier, about 120 denier, about 150 denier, and about 170 denier, where the filament count in the yarn ranges from about 10 to about 100. Figure 5B An exemplary single-sided jersey knit with a knit - float pattern is shown, where 206 shows a missstitch and 208 is a knit stitch. The multi-component yarn 212 and one or more other yarns 214 can be placed side by side. In some aspects, such a pattern can have variations in the stitch combination ranging from knit - knit - float to knit - knit - knit - float, as Figure 5C shown, where 210 is a tuckstitch and 208 is a knit stitch, and the multi-component yarn 212 and one or more other yarns 214 are placed side by side.

[0086] Figure 5D A knit and tuck combination is shown, which involves feeding two yarns in a plating relationship to a needle with a front hook. An exemplary covered TPU core yarn 302 is fed at a high level and is received only by the needles selected to this height. One or more other yarns 304, e.g., fine yarns with a fineness of 10 denier to 100 denier - including exemplary values of about 20 denier, about 30 denier, about 40 denier, about 50 denier, about 60 denier, about 70 denier, about 80 denier, and about 90 denier - are fed at a lower level and are received and knitted by each needle. At the first two feeders, the odd-numbered needles (1 and 3) only knit the fine yarn, while the even-numbered needles (2 and 4) knit plated loops. At the last two feeders, the order can be reversed.

[0087] In still other aspects, when the textile has a knitted structure (e.g., weft knitting, warp knitting, or crocheting) and in the absence of a second yarn, a first more elastic yarn is used in the weft direction of the textile. In such an exemplary aspect, the warp direction may include the one or more other yarns. In still yet other exemplary aspects, when the weft direction of the textile includes a first yarn (in the absence of a second yarn, e.g., not a multi-component yarn), the warp direction may include a combination of the one or more other yarns and the first yarn placed side by side, or any other desired pattern.

[0088] In still other aspects, when a second yarn is present, e.g., where there is a multi-component yarn, it is positioned in the warp direction. In such an exemplary aspect, the warp direction may further include the one or more other yarns. In such an aspect, the multi-component yarn and the one or more other yarns are present in a ratio of from about 1:2 to about 1:10, including exemplary values of about 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, and 1:9.

[0089] In some exemplary and non-limiting aspects, when the textile has a crocheted structure, the warp direction of such a textile may include a first yarn. However, in such an aspect, the warp direction may further include the one or more other yarns in a ratio of from about 1:2 to about 1:10, including exemplary values of about 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, and 1:9. In still other aspects, the weft may include a first yarn that may or may not be covered.

[0090] In still other aspects, when the first yarn is not covered by the second yarn and the structure is weft knitting, the textile may include plaiting of the first yarn and the one or more other yarns.

[0091] In still other aspects, the textile may have a woven structure. A woven base layer is understood to be distinguished from a knitted fabric in that a woven base layer is constructed by longitudinally and transversely interlacing or weaving at least two warp and weft yarns to create a woven base layer. In certain aspects, due to the nature of the interlaced warp and weft yarn structure, a woven base layer does not have high stretchability unless the structure includes stretchable yarns. This is in contrast to knitted textiles, which are made of interlocking loops that give the resulting knitted textile a high stretchability, regardless of whether the yarns themselves are stretchable. The stretchability of knitted textiles can be further enhanced by using the elastomeric yarns disclosed herein.

[0092] In other aspects disclosed herein, the woven structure can include a plain weave, derivatives of plain weave, rib weave, basketweave, twill weave, satin weave, dobby weave, jacquard weave, extra yarn weave, pique weave, double cloth textile, crepe weave, leno weave, pile weave, triaxial weave, or combinations thereof.

[0093] In some aspects, in the absence of a multi-component yarn, e.g., when only the first yarn is present, the weft direction of the textile includes the first yarn. In such exemplary and non-limiting aspects, the warp direction can include the one or more other yarns. However, in yet other exemplary aspects, when the first yarn is present in the weft direction, the warp direction can include a combination of the one or more other yarns and the first yarn.

[0094] In yet other aspects, when the textile is woven and the first yarn is covered by a second yarn, i.e., a multi-component yarn is formed, the warp direction of the textile includes the multi-component yarn and the one or more other yarns, in a ratio of from about 1:2 to about 1:10, including exemplary values of about 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, and 1:9.

[0095] In some exemplary aspects, when a multi-component yarn is present in a woven textile, such textile can further include a third yarn different from the first yarn. In yet other aspects, the third yarn can also be different from the one or two other yarns. In yet other aspects, the third yarn can include a third polymer, the third polymer including polyester, nylon, polyolefin, polyurethane, or combinations thereof. In yet other aspects, any one of the polyesters, nylons, polyolefins, polyurethanes, or combinations thereof disclosed above can be used to form the third yarn.

[0096] In still yet other aspects, the third yarn can further include a fully drawn yarn, a spun-drawn yarn, a low twist or non-twist yarn, a twisted yarn, a flat yarn, a textured yarn, a high bulk textured yarn, a high shrinkage yarn, or any combination thereof. In yet other aspects, the third yarn can be a textured yarn.

[0097] In still other aspects, when the multi-component yarn is present in the woven textile, the weft direction of such a textile may include the one or more other yarns.

[0098] In certain aspects, the woven textile can be formed such that the multi-component yarn is provided by a first warp beam, the one or more other yarns are provided by a second warp beam, and a third yarn (if present) is provided by a third warp beam. In such an exemplary aspect, the multi-component yarn woven in the warp direction is present at a different tension than the tension of the one or more other yarns and / or the tension of the third yarn. In certain aspects, the tension of the multi-component yarn is lower than the tension of the one or more other yarns and / or the tension of the third yarn. However, in still other aspects, the tension of the multi-component yarn in the warp direction can be greater than the tension of the one or more other yarns in the warp direction and / or the tension of the third yarn in the warp direction. In such an exemplary aspect, the multi-component yarn is woven at a higher tension and, after weaving is complete, it can spring back to its original size, thereby allowing the textile to have additional stretchability. However, in other exemplary aspects, when the multi-component yarn is woven in the warp direction, for example, at a lower tension than the other yarns, at the end of weaving, it can also provide additional stretch of the textile. In still other aspects, the third yarn can be woven in the warp direction separately from the multi-component yarn and / or the one or more other yarns.

[0099] In still other exemplary aspects, when compared to a substantially identical reference textile lacking the third yarn, the third yarn can form longer floats or raised features / s on the surface of the textile. In such an exemplary aspect, the woven textile can have a higher surface area compared to a substantially identical reference textile lacking the third yarn. These features are very useful in some medical devices that require high surface area textiles (e.g., in grafts, in implantable devices, etc.).

[0100] In still other aspects, the textile can have a predetermined woven pattern that includes the multi-component yarn and the one or more other yarns arranged alternately side by side in the warp direction. In such an aspect, the one or more other yarns in the warp direction are textured yarns, high stretch (HS) textured yarns, high bulk textured yarns, and / or high shrinkage yarns. However, in other aspects, the one or more other yarns in the weft direction can also be flat yarns or twisted yarns, textured yarns, high stretch (HS) textured yarns, high bulk textured yarns, and / or high shrinkage yarns.

[0101] For example, Figure 4Shows an exemplary and non - limiting design of a textile 400, in which an exemplary multi - component yarn 402 having a TPU core is woven with a textured yarn 404 and a high - bulk textured yarn 406 in the warp direction.

[0102] In still other exemplary and non - limiting aspects, in a woven textile, the warp density of the multi - component yarn can be from about 10 warps per inch to about 200 warps per inch, including exemplary values of about 20 warps per inch, about 50 warps per inch, about 70 warps per inch, about 100 warps per inch, about 120 warps per inch, about 150 warps per inch, and about 170 warps per inch.

[0103] In still other aspects, the warp density of one or more other yarns including textured yarns, high - stretch (HS) textured yarns, high - bulk textured yarns, and / or high - shrinkage yarns is from about 10 warps per inch to about 200 warps per inch, including exemplary values of about 20 warps per inch, about 50 warps per inch, about 70 warps per inch, about 100 warps per inch, about 120 warps per inch, about 150 warps per inch, and about 170 warps per inch.

[0104] In still further other aspects, the weft density is from about 10 wefts per inch to about 200 wefts per inch, including exemplary values of about 20 wefts per inch, about 50 wefts per inch, about 70 wefts per inch, about 100 wefts per inch, about 120 wefts per inch, about 150 wefts per inch, and about 170 wefts per inch.

[0105] The permeability of a woven textile can be adjusted by changing the aperture of the woven textile defined by adjacent warps and wefts. This can be achieved by selecting the yarns and / or changing the number of warps per inch and the number of wefts per inch of the woven textile. Optionally, the permeability can be further adjusted by using any of the woven patterns disclosed herein. In still other aspects, the aperture in a woven fabric can be controlled by the selection of the yarns, i.e., yarn fineness, number of warps, weft density, and weave pattern. In a knitted fabric, the aperture can be further controlled by the gauge used in the knitting machine, which specifies the number of yarns per inch, i.e., 40 gauge = 40 yarns per inch. In addition to textile forming methods such as weaving, knitting, and / or braiding, some post - treatments such as high - temperature heat treatment can also be used to adjust the permeability or aperture.

[0106] In still other aspects, the textile can have a braided structure. In such an exemplary aspect, the braided structure can be biaxial, triaxial, uniaxial, or a combination thereof. In still other aspects, the braided structure can include a core and a sheath.

[0107] It should be understood that the braided construction can include three or more yarns twisted in such a way that no two yarns are twisted back with each other. In yet other aspects, the braided construction can also be referred to as a family of textiles woven continuously on the bias. It should also be understood that the braided construction of a textile can be manufactured and used as an independent textile with a constant braiding angle (acute angle measured from the braiding axis to the twill yarn axis).

[0108] It will be further appreciated that while braided constructions are similar to woven constructions in that the yarns are mechanically interlocked with one another because the yarns are also continuous, braiding can have a natural mechanism that evenly distributes loads throughout the structure, making braided constructions impact resistant and useful in a variety of applications.

[0109] In such exemplary aspects, if the second yarn is not present, the core of the braided construction comprises the first yarn, and the sheath comprises the one or more other yarns. However, in other aspects, when the second yarn is present, the sheath comprises the multi-component yarn. In such exemplary aspects, the braided construction may further comprise other first yarns that are not covered by the second yarn, and this other first yarn may be present in the core of the braided construction.

[0110] In other aspects, the textile can have any desired thickness. For example, and without limitation, in other aspects, the thickness of the textile can be about 0.1 mm to about 10 mm, including example values ​​of about 0.2 mm, about 0.3 mm, about 0.4 mm, 0.5 mm, about 0.6 mm, about 0.7 mm, about 0.8 mm, about 0.9 mm, about 1 mm, about 1.5 mm, about 2 mm, about 2.5 mm, about 3 mm, about 3.5 mm, about 4 mm, about 4.5 mm, about 5 mm, about 5.5 mm, about 6 mm, about 6.5 mm, about 7 mm, about 8.5 mm, about 9 mm, and about 9.5 mm. In other aspects, the first textile thickness can have any value between any two of the aforementioned values.

[0111] In yet other aspects, the textile can have any desired length. For example, and without limitation, the length of the textile can be from about 1 mm to about 100 mm, including exemplary values of about 2 mm, about 5 mm, about 7 mm, about 10 mm, about 12 mm, about 15 mm, about 17 mm, about 20 mm, about 22 mm, about 25 mm, about 27 mm, about 30 mm, about 32 mm, about 35 mm, about 37 mm, about 40 mm, about 42 mm, about 45 mm, about 47 mm, about 50 mm, about 52 mm, about 55 mm, about 57 mm, about 60 mm, about 62 mm, about 65 mm, about 67 mm, about 70 mm, about 72 mm, about 75 mm, about 77 mm, about 80 mm, about 82 mm, about 85 mm, about 87 mm, about 90 mm, about 92 mm, about 95 mm and about 97 mm. It should be understood that these values are exemplary and not restrictive, and the textile can have any length value between any two of the foregoing values. It should also be understood that if the specified application requires a length for the textile, it can be about 150 mm, about 200 mm or about 1 m.

[0112] In yet other aspects, the textile can have any desired width. In yet other aspects, the width of the textile can be from about 1 mm to about 100 mm, including exemplary values of about 2 mm, about 5 mm, about 7 mm, about 10 mm, about 12 mm, about 15 mm, about 17 mm, about 20 mm, about 22 mm, about 25 mm, about 27 mm, about 30 mm, about 32 mm, about 35 mm, about 37 mm, about 40 mm, about 42 mm, about 45 mm, about 47 mm, about 50 mm, about 52 mm, about 55 mm, about 57 mm, about 60 mm, about 62 mm, about 65 mm, about 67 mm, about 70 mm, about 72 mm, about 75 mm, about 77 mm, about 80 mm, about 82 mm, about 85 mm, about 87 mm, about 90 mm, about 92 mm, about 95 mm and about 97 mm. It should be understood that these values are exemplary and not restrictive, and the textile can have any width value between any two of the foregoing values. It should also be understood that if the specified application requires a first width, it can be about 150 mm, about 200 mm or even about 1 m.

[0113] In yet other aspects, the textiles disclosed herein can exhibit an elastic recovery rate of at least about 80% relative to the original size, at least about 85% relative to the original size, at least about 90% relative to the original size, at least about 95% relative to the original size, at least about 99% relative to the original size, or a recovery rate of even 100% relative to the original size.

[0114] In still other aspects, the disclosed textiles can be stretched while exhibiting the elastic recovery rates disclosed above along the longitudinal axis, transverse axis, or across the textile. In still other aspects, when the textile has a woven or knitted construction, elastic recovery can also occur along the axial direction or along an offset direction. In such aspects, the textile can have an ultimate elongation of from about 50% to about 700% along its length or width, including exemplary values of about 100%, about 150%, about 200%, about 250%, about 300%, about 350%, about 400%, about 450%, about 500%, about 550%, about 600%, and about 650%. In still other aspects, the first polymer can have an ultimate elongation value between any two of the foregoing values. It should also be understood that the textiles disclosed herein can have the same or different ultimate elongations measured along the width or length of the textile.

[0115] In still other aspects, when any of the textiles disclosed herein are compressed across their thickness, they can exhibit a compressibility of from about 10% to about 50% measured according to standard methods and at standard pressure, including exemplary values of about 15%, about 20%, about 25%, about 30%, about 35%, about 40%, and about 45%.

[0116] In still other aspects, the fibers present in any of the yarns disclosed herein can have any diameter suitable for the desired application. In some aspects, the diameter of the fibers can be from about 1 μm to about 25 μm, including exemplary values of about 2 μm, about 5 μm, about 7 μm, about 10 μm, about 12 μm, about 15 μm, about 17 μm, about 20 μm, and about 22 μm. It should be understood that the fibers can have any diameter between any two of the foregoing values. For example, and without limitation, the diameter of the fibers can be from about 3 μm to about 8 μm, or from about 11 μm to about 22 μm, or from about 15 μm to about 25 μm.

[0117] It should also be understood that the aspects described herein include biocompatible yarns. Aspects are also disclosed herein that include yarns of permanent implant-grade polymers. In still other aspects, the permanent implant-grade polymers can include, but are not limited to, polyesters, copolyesters, ultra-high molecular weight polyethylene, polyethylene, polypropylene, polytetrafluoroethylene, expanded polytetrafluoroethylene, polyvinylidene fluoride, polyurethanes, polyethers, polyureas, nylons, their copolymers, or combinations thereof.

[0118] In still other aspects, the textiles disclosed herein can exhibit high stretchability, self-conformability to a substrate, retention of a predetermined suture, retention of a predetermined fabric density, retention of pore size, retention of thickness, or combinations thereof.

[0119] In still other aspects, the textile can further include an active ingredient, where the active ingredient can include a medicament, therapeutic agent, antimicrobial agent, or any combination thereof.

[0120] In still other aspects, the textiles disclosed herein can be dip-coated, spray-coated, glued, or laminated with a film or membrane, any material suitable for the desired application. For example, the textiles can be coated with a polymer, a drug, a hydrophobic / hydrophilic agent, a lubricating polymer, or any combination thereof.

[0121] In still other aspects, the polymers used for coating can include thermoplastic polyurethanes, silicones, or any combination thereof. It should be understood that in some exemplary and non-limiting aspects, the coating can be used to form an impermeable barrier. Again, in such exemplary and non-limiting aspects, such a coating can at least partially cover the pores in the textile structure while still maintaining the stretchability / elasticity of the structure.

[0122] In still other aspects, the textiles disclosed herein can be at least partially biostable. It should be understood that the term "biostable" refers to a textile that remains at least partially intact during the period that a medical article and / or device is intended to remain in the body. However, in other aspects, the textile can be at least partially biodegradable. The term "biodegradable" as used herein can refer to a textile that at least partially degrades, e.g., due to dissolution or chemical decomposition, during the period that a medical article and / or device is intended to remain in the body.

[0123] It should be understood that variations in the polymer content can affect the physical and chemical properties of the textile, such as mechanical strength, hardness, surface tackiness, elasticity, compressibility, permeability, water diffusivity, therapeutic agent diffusivity (when present), degradation rate (when biodegradable), and hydrophobic / hydrophilic properties (affecting, e.g., wettability and water and therapeutic agent diffusivity, if present), among others.

[0124] In still other aspects, the textile is configured for suturing. It should be understood that any suture known in the art can be used. In certain exemplary and non-limiting aspects, the suture is a textile filament. In still other aspects, the suture is any filament suitable for the desired application.

[0125] Medical article and / or device

[0126] Also disclosed herein are articles comprising any of the textiles disclosed herein. Such articles can include any medical device having a textile component and configured to contact an object's body and / or body fluids. In still other aspects, such articles can include implantable devices. In still other aspects, the article can include a tissue scaffold.

[0127] It will be appreciated that the textiles disclosed herein can be used to form a variety of medical devices. For example, devices such as closed-volume (hollow) medical devices, such as tubular articles (e.g., vascular and non-vascular grafts and stent-grafts, including large and small vascular grafts such as coronary artery bypass grafts, peripheral vascular grafts, and endovascular grafts; other tubular structures such as biliary, urethral, ureteral, intestinal, and esophageal tubular structures, etc.), and various open-volume medical devices such as vascular and non-vascular patches (e.g., patches for wound healing, patches for hernia repair, and patches for the gastrointestinal and genitourinary systems). Other examples of medical devices include: vascular and non-vascular tissue scaffolds, vascular and non-vascular closure devices, e.g., devices for closing peripheral and arteriovenous fistulas, sutures, meshes, valve leaflets of heart valves and venous valves; vascular access devices, including vascular access ports and arteriovenous access grafts (e.g., devices for frequent access to arteries and / or veins, such as for antibiotics, total parenteral nutrition, intravenous fluids, blood transfusions, blood sampling, or arteriovenous access for hemodialysis, etc.); embolus filters (e.g., distal protection filters); uterine slings; fabrics for connecting LVADs (left ventricular assist devices) and TAHSs (total artificial hearts) to the human arteries, and the like.

[0128] In some aspects, medical articles and / or devices comprising the textiles disclosed herein may be suitable for long-term implantation. As used herein, the term "long-term" implantation refers to an implantation period greater than 30 days, e.g., ranging from 1 month to 3 months to 6 months to 12 months to 24 months or even longer, including the remaining life of the patient. In cases where a hollow (including tubular) medical device is provided to augment, repair, or replace a body cavity (e.g., stents, grafts, stent-grafts, patches, etc.), its dimensions can be customized to approximate the dimensions of all or part of the body cavity. Examples of body cavities include: the cavities of the cardiovascular system such as the heart, arteries, and veins (e.g., coronary arteries, femoral arteries, aorta, iliac arteries, carotid arteries, and vertebrobasilar arteries); the cavities of the genitourinary system such as the urethra (including the prostatic urethra), bladder, ureters, vagina, uterus, spermatic cords, and fallopian tubes, nasolacrimal ducts, eustachian tubes; the cavities of the respiratory tract such as the trachea, bronchi, nasal passages, and sinuses; the cavities of the gastrointestinal tract such as the esophagus, digestive tract, duodenum, small intestine, large intestine, colon, bile ducts, and pancreatic duct system; the cavities of the lymphatic system; and so on.

[0129] Thus, the diameter of the hollow medical devices (including any tubular shape, e.g., devices having circular and oval cross-sections) for use in the present invention can vary widely, e.g., in the range of 0.5 mm to 1 mm to 2 mm to 5 mm to 10 mm to 20 mm to 50 mm or more. For example, tubular articles with a diameter of 0.5 to 2 mm can be used for microvascular work and catheters for nerve regeneration, tubular articles with a diameter of 2 to 4 mm can be used for coronary artery bypass, tubular articles with a diameter of 2 to 10 mm can be used for peripheral vascular grafts, tubular articles with a diameter of 20 to 50 mm and above can be used for endovascular and intraluminal vascular grafts, other tubular prostheses such as esophageal and colon prostheses, and the like.

[0130] In still other aspects, the textiles disclosed herein can be used to address issues associated with paravalvular leakage (PVL). PVL is a complication associated with the implantation of prosthetic heart valves. PVL refers to the passage of blood flow through the space between the structure of the implanted valve and the heart tissue due to a lack of proper sealing. Most PVLs are crescent-shaped, oval-shaped, or slightly round in shape, and their trajectories can be parallel, perpendicular, or serpentine. Transcatheter heart valve (THV) procedures typically use substantially non-elastic woven fabrics or stretchable knitted fabrics for PVL sealing. It should be understood that the stretchability of the textile can be an important factor as it helps to reduce the stress on the tissue to which the medical device incorporating the textile is attached.

[0131] As the frame sizes of the new generation of THV frame designs are constantly changing, one requirement is that the PVL sealing fabric and / or the fabric within the frame be able to adapt to the changing frame sizes. Thus, there is a need for a fabric that has controlled stretchability and a lower profile to provide improved compliance by reducing the potential stress at the location where the fabric is fixed to the body cavity.

[0132] In some exemplary aspects, the textiles described herein can be used in implantable medical devices, the medical device comprising: an annular frame having an inflow end, an outflow end, and a longitudinal axis; and a sealing element fixed to the frame, wherein the sealing element comprises any of the textiles disclosed herein.

[0133] In certain exemplary and non - limiting aspects, implantable prosthetic valves are disclosed herein, which include: an annular frame having an inflow end, an outflow end, and a longitudinal axis, wherein the annular frame is configured to expand and contract; and a sealing element fixed to the frame, wherein the sealing element includes a textile, and the textile includes: a) a first yarn including one or more filaments, the filaments including a first polymer; b) one or more other yarns having a composition and / or properties different from the first yarn. In some aspects, the first yarn exhibits higher elasticity than the one or more other yarns. In certain aspects, the textile exhibits an ultimate elongation of from about 50% to about 700% and has shape adaptability and biocompatibility. In some embodiments, the textile is configured to be inserted and / or implanted into a subject's body.

[0134] Exemplary aspects of implantable medical devices are shown in Figures 6 - 7 which. One exemplary and non - limiting aspect includes a medical device that is a prosthetic heart valve. For example, and without limitation, Figure 6 illustrates an exemplary aspect of a radially collapsible and expandable prosthetic valve 10 shown in its deployed, expanded configuration. The prosthetic valve can include an annular stent or frame 12 and a leaflet structure 14 located within and coupled to the frame 12. The frame 12 can have an inflow end portion 16 and an outflow end portion 18. The leaflet structure can include a plurality of leaflets 22. In certain aspects, the leaflet structure can include three leaflets. In such an exemplary aspect, such three leaflets can be arranged to collapse in a tricuspid arrangement similar to the aortic valve. Optionally, the prosthetic valve can include two leaflets 22 configured to fold in a bicuspid arrangement similar to the mitral valve, or more than three leaflets, depending on the specific application. The prosthetic valve 10 can define a longitudinal axis 24 extending through the inflow end portion 16 and the outflow end portion 18.

[0135] The frame 12 can be made of various biocompatible materials such as stainless steel or nickel - titanium alloy (“NiTi”), e.g., nitinol. Referring to Figure 6 , the frame 12 can include a plurality of interconnected grid struts 26 arranged in a grid - like pattern and forming a plurality of vertices 28 at the outflow end 18 of the prosthetic valve. The struts 26 can also form similar vertices (covered by a skirt 30 described in more detail below) at the inflow end 16 of the prosthetic valve. The grid struts 26 are shown positioned or offset obliquely at an angle radially offset from and with respect to the longitudinal axis 24 of the prosthetic valve. It should be understood that Figure 6 the configuration shown is merely exemplary, and in other aspects, the amount by which the grid struts 26 are offset can be different from Figure 6 that shown, or some or all of the grid struts 26 can be positioned parallel to the longitudinal axis of the prosthetic valve.

[0136] The lattice struts 26 can be pivotally coupled to each other. In the illustrated aspect, for example, the ends of the struts 26 that form vertices 28 at the outflow end 18 and the inflow end 16 of the frame may have corresponding openings 32. The struts 26 may also be formed with holes 34 located between opposite ends of the struts. Corresponding hinges can be formed at the vertices 28 and at the locations where the struts 26 overlap each other between the frame ends by fasteners 36, which may include rivets or pins extending through the holes 32, 34. The hinges can allow the struts 26 to pivot relative to each other when the frame 12 is expanded or contracted (or crumpled), such as during the assembly, preparation, and implantation of the prosthetic valve 10. For example, the frame 12 (and thus the prosthetic valve 10) can be manipulated into a radially compressed or contracted (crumpled) configuration, coupled to a delivery device, and inserted into a patient for implantation. Once in the body, the prosthetic valve 10 can be manipulated into an expanded state and then released from the delivery device. Other details regarding the frame 12, the delivery device, and the apparatus and techniques for radially expanding and crumpling the frame can be found in U.S. Publication No. 2018 / 0153689, which is incorporated herein by reference. Other details regarding such an exemplary prosthetic valve can also be found in U.S. Publication No. 2019 / 0046314, which is incorporated herein by reference.

[0137] As Figure 6 shown, the prosthetic valve 10 may include a sealing element configured as a skirt 30. The skirt 30, as shown herein, may include any of the textile materials disclosed above. It should be understood that in some aspects, the skirt 30 is an outer skirt. In such aspects, another skirt (not shown), referred to as an inner skirt, may be attached to the frame and located below the outer skirt 30. However, in some aspects, the textile material used for the outer skirt 30 may also be used for the inner skirt (not shown here). However, in some aspects, the inner skirt does not include the textile material for the outer skirt. In still other aspects, only one skirt is used. In such aspects, such a skirt may include any of the textile materials described herein.

[0138] The skirt 30 can be configured to establish a seal against native tissue at the treatment site to reduce or prevent paravalvular leakage. The skirt 30 can include a body portion 38 disposed about the outer circumference of the frame 12. In some aspects, for example, the textile or skirt shown herein can be secured to the frame by fasteners. The fasteners can include sutures, pins, rivets, ultrasonic welding, laser welding, adhesive bonding, or any combination thereof. In this example, the skirt 30 can be secured to the frame by, for example, a plurality of sutures 41 that extend in a zigzag pattern between a first edge portion (e.g., the inflow edge portion) 40 and a second edge portion (e.g., the outflow edge portion) 42 of the skirt 30 along selected strut members 26. For example, in some aspects, the skirt 30 can be sutured to the frame 12 along a suture path 66 corresponding to the scalloped edge defined by the leaflets 22, which can allow the valve to radially expand and contract (crimp) without interference or squeezing by the skirt. Additional details regarding transcatheter prosthetic heart valves, including the manner in which the leaflets 22 can be coupled to the frame 12, can be found, for example, in U.S. Patent Nos. 6,730,118, 7,393,360, 7,510,575, 7,993,394, and 8,652,202, the entire contents of which are incorporated herein by reference.

[0139] It should be understood that the skirt 30 including the textile material disclosed herein provides better dimensional stability, which is helpful in procedures that involve joining valve components together using sutures and laser cutting of components. The disclosed textile allows the skirt 30 to accommodate varying frame sizes and provides a low profile for such a skirt.

[0140] Figure 7 Another aspect of the prosthetic valve 10, including a sealing member or skirt 600, is illustrated. In the shown and non-limiting aspect, the skirt 600 includes a textile material that is described herein and is configured as a fabric strip 602 having an edge portion 608. In some exemplary aspects, the skirt 600 can be secured to the struts 26 to form a layer of the skirt (not shown). It should also be understood that skirts of any configuration coupled to the frame can be used depending on the desired application.

[0141] The textile materials described herein can be used in any sealing element aspect and in any combination with any prosthetic valve and / or frame aspect. It should be understood that a prosthetic heart valve can also include any of the textile materials described herein, or any combination of portions thereof.

[0142] The textiles of the prosthetic seal members described herein can be configured to promote a biological response to form a seal between the prosthetic valve and the surrounding anatomy. In certain configurations, the seal elements described herein can be configured to form a seal over a selected period of time. In certain aspects, the seal members of the perivalvular seal structure can be treated with one or more agents that inhibit the biological response to the seal structure. For example, in certain exemplary aspects, the textiles of the present disclosure can be treated with heparin. In certain aspects, the amount or concentration of the agent(s) can be selected such that the agent(s) is depleted after a selected period of time (e.g., days, weeks, or months) following valve implantation. When the agent(s) is depleted, the biological response to the textiles or yarns or fibers of the seal structure increases such that a perivalvular seal gradually forms over the selected period of time. This is advantageous for patients who have undergone left atrial remodeling (e.g., due to mitral regurgitation) by providing an opportunity for remodeling reversal - since the regurgitation across the prosthetic valve gradually decreases.

[0143] Method

[0144] The present disclosure also provides a method that includes forming a textile that includes: a) a first yarn including one or more filaments that include a first polymer; b) one or more other yarns having a composition and / or properties different from the first yarn; and c) optionally a second yarn including one or more filaments that include a second polymer, where if the second yarn is present, the second yarn coats the first yarn to form a multicomponent yarn such that the first yarn forms a core and the second yarn forms a sheath, where the first yarn exhibits a higher elasticity than the elasticity of the one or more other yarns and, if the second yarn is present, the elasticity of the second yarn; and where the textile exhibits an ultimate elongation of from about 50% to about 700% and has shape adaptability and biocompatibility and is configured to be inserted and / or implanted into the body of a subject.

[0145] Any of the first yarn, second yarn, and the one or more other yarns disclosed herein can be used. In certain aspects, and as described above, the forming step can further include using any of the third yarns disclosed above.

[0146] In certain aspects, the forming step can include a step of weaving, knitting, braiding, or any combination thereof. It should also be understood that any of the structures disclosed above can be formed.

[0147] The present disclosure also provides a method of manufacturing an implantable medical device that includes: providing a seal element of any of the textiles disclosed herein and securing the seal element to an annular frame of the implantable medical device.

[0148] In still other aspects, any of the implantable medical devices disclosed herein can be formed by such methods. In still other aspects, any of the textiles disclosed herein can be used to form a sealing element of the device. In still other aspects, any method commonly used to secure a sealing element to an annular frame can be used. For example, and without limitation, the sealing element can be secured to the annular frame of the device with sutures. Any suture known in the art can be used. In some exemplary and non-limiting aspects, the suture can include a textile-based material. However, it should be understood that any suture suitable for the desired application can be used.

[0149] In still other aspects, the methods disclosed herein can include the step of impregnating any of the textile materials disclosed herein with a pharmaceutically active agent, depending on the desired application. In still other aspects, the methods disclosed herein can include the step of coating any of the textile materials disclosed herein with a material known in the prior art that can provide any other desired property.

[0150] Examples

[0151] The following examples are provided to give a complete disclosure and description to those of ordinary skill in the art of how to make and evaluate the compounds, compositions, articles, devices, and / or methods claimed herein. The purpose is purely exemplary and not limiting of the disclosure. Efforts have been made to ensure the accuracy of the numbers (e.g., amounts, temperatures, etc.), but some errors and deviations should be accounted for.

[0152] Unless otherwise indicated, parts are by weight, temperature is in degrees Celsius or at ambient temperature, and pressure is atmospheric or full vacuum, or near atmospheric or full vacuum.

[0153] Example 1

[0154] In this example, the textile is formed from TPU-coated yarns. First, the TPU polymer is extruded using melt spinning to the desired monofilament fineness to form monofilament yarns or multifilament yarns.

[0155] Table 1 shows the various properties of the TPU materials used for extrusion. In some examples, a medical grade of TPU of 93 - 100A is used for extrusion.

[0156] The TPU yarns are then coated with PET multifilament yarns. When processed on textile equipment, high bulk texturized yarns are used for coating to prevent direct contact of the TPU filaments with the metal surface. The coated TPU yarns are then knitted (warp or weft knitting), woven, or braided into a textile structure. The elastic textile structure is then coated with a TPU spray or dip coating.

[0157] Table 1. Physical properties of TPU.

[0158]

[0159] *ASTM standard

[0160] The TPU for coating has the properties shown in Table 2. Higher TPU grade solids % (20%+) for coating can reduce the tackiness of the TPU.

[0161] Table 2. TPU properties

[0162]

[0163] Exemplary aspects

[0164] In view of the methods and compositions, certain more specifically described aspects of the present disclosure are described below. However, these specifically recited aspects should not be construed as having any limiting effect on any of the different claims that contain the different or more general teachings described herein, or as being "specific" aspects limited in some way other than the inherent meaning of the language and formulas literally used herein.

[0165] Example 1: A textile, comprising: a) a first yarn comprising one or more filaments, the filaments comprising a first polymer; b) one or more other yarns having a composition and / or properties different from the first yarn; wherein the first yarn exhibits higher elasticity than the one or more other yarns, the textile exhibits an ultimate elongation of from about 50% to about 700% and has shape adaptability and biocompatibility, and wherein the textile is configured to be inserted and / or implanted into the body of an object.

[0166] Example 2: Any example herein, particularly the textile of Example 1, wherein the first polymer comprises thermoplastic polyurethane (TPU), polyurethane (PU), thermoplastic elastomer (TPE), elastomeric polyolefin, polybutylene terephthalate (PBT), silicone-based elastomer, or a combination thereof.

[0167] Example 3: Any example herein, particularly the textile of Example 1 or 2, wherein the hardness of the first polymer is from about 75A to about 75D.

[0168] Example 4: Any example herein, particularly the textile of Examples 1-3, wherein the ultimate tensile strength of the first polymer is between about 4500 psi and about 8000 psi.

[0169] Example 5: Any example herein, particularly the textile of Examples 1-4, wherein the ultimate elongation of the first polymer is between about 50% and about 700%.

[0170] Example 6: Any example herein, particularly the textile of Examples 1-5, wherein the first polymer is TPU.

[0171] Example 7: Any example herein, particularly the textiles of Examples 1-6, wherein the first yarn is a monofilament.

[0172] Example 8: Any example herein, particularly the textiles of Examples 1-6, wherein the first yarn is a multifilament.

[0173] Example 9: Any example herein, particularly the textiles of Example 8, wherein the filament count of the first yarn is greater than about 1 to about 50.

[0174] Example 10: Any example herein, particularly the textiles of Examples 1-9, wherein the fineness of one or more filaments of the first yarn ranges from about 5 denier to about 1000 denier.

[0175] Example 11: Any example herein, particularly the textiles of Examples 1-10, wherein there is more than one other yarn, and these other yarns are the same or different.

[0176] Example 12: Any example herein, particularly the textiles of Examples 1-11, wherein the one or more other yarns include fully drawn yarn, spun-drawn yarn, low-twist or non-twist yarn, twisted yarn, flat yarn, textured yarn, high-stretch (HS) textured yarn, high-bulk textured yarn, high-shrinkage yarn, or any combination thereof.

[0177] Example 13: Any example herein, particularly the textiles of Examples 1-12, wherein the one or more other yarns include polyolefin, polyester, polyurethane, thermoplastic polyurethane, polyamide, or a combination thereof.

[0178] Example 14: Any example herein, particularly the textiles of Examples 1-13, wherein the one or more other yarns are substantially rigid or semi-rigid.

[0179] Example 15: Any example herein, particularly the textiles of Examples 1-14, further comprising a second yarn, the second yarn including one or more filaments comprising a second polymer.

[0180] Example 16: Any example herein, particularly the textiles of Example 15, wherein the second yarn is different from the first yarn.

[0181] Example 17: Any example herein, particularly the textiles of Example 15 or 16, wherein the second yarn coats the first yarn to form a multicomponent yarn such that the first yarn forms a core and the second yarn forms a sheath.

[0182] Example 18: Any example herein, particularly the textiles of Examples 15-17, wherein the elasticity of the first polymer is higher than that of the second polymer.

[0183] Example 19: Any example herein, particularly the textiles of Examples 15-18, wherein the second polymer comprises polyester, nylon, polyolefin, or a combination thereof.

[0184] Example 20: Any example herein, particularly the textiles of Example 19, wherein the second polymer comprises polyethylene terephthalate (PET) homopolymers and copolymers, polypropylene terephthalate (PPT) homopolymers and copolymers, and polybutylene terephthalate (PBT) homopolymers and copolymers, or any combination thereof.

[0185] Example 21: Any example herein, particularly the textiles of Examples 15-20, wherein the second yarn is a monofilament.

[0186] Example 22: Any example herein, particularly the textiles of Examples 15-20, wherein the second yarn is a multifilament.

[0187] Example 23: Any example herein, particularly the textiles of Example 22, wherein the filament count of the second yarn is greater than 1 to about 150.

[0188] Example 24: Any example herein, particularly the textiles of Examples 15-23, wherein the fineness of one or more filaments of the second yarn ranges from about 5 denier to about 1000 denier.

[0189] Example 25: Any example herein, particularly the textiles of Examples 17-24, wherein the multicomponent yarn is single-covered or double-covered.

[0190] Example 26: Any example herein, particularly the textiles of Example 25, wherein the multicomponent yarn is double-covered, and two second yarns cover the first yarn in opposite directions.

[0191] Example 27: Any example herein, particularly the textiles of Examples 15-26, wherein the second yarn comprises fully drawn yarn, spun-drawn yarn, low-twist or non-twist yarn, twisted yarn, flat yarn, textured yarn, high-stretch (HS) textured yarn, high-bulk textured yarn, high-shrinkage yarn, or any combination thereof.

[0192] Example 28: Any example herein, particularly the textiles of Examples 1-27, wherein one or more filaments of the first yarn are melt-spun.

[0193] Example 29: Any example herein, particularly the textiles of Examples 1-28, wherein the textile has a knitted, woven, or braided structure.

[0194] Example 30: Any example herein, particularly the textile of Example 29, wherein the textile comprises a simple single-sided jersey knit construction; a single-sided jersey knit with a knit - float pattern construction; a single-sided jersey knit with a knit - tuck pattern construction; tricot warp knitting, plain velour stitch, satin knit, warp velour stitch, warp twill stitch, purl knitting, rib stitch, lockstitch double rib, double-sided knitting, warp knitting, raschel knitting corded pattern, bird's eye pattern knitting, pontell knitting, intarsia knitting, jacquard knitting, terry knitting textile, knitted velvet textile, wool-fed knitting, raised knitting, or any combination thereof.

[0195] Example 31: Any example herein, particularly the textile of Example 29 or 30, wherein the textile has a warp knitting, weft knitting (circular or flat), or crocheted construction.

[0196] Example 32: Any example herein, particularly the textile of Example 29, wherein the textile has a woven construction.

[0197] Example 33: Any example herein, particularly the textile of Example 32, wherein the woven construction includes plain weave, derivatives of plain weave, double plain weave, basket weave, twill weave, satin weave, dobby jacquard, jacquard, extra yarn construction, raised and depressed texture, double-layer fabric textile, crepe weave, leno weave, pile weave, triaxial weave, or a combination thereof.

[0198] Example 34: Any example herein, particularly the textile of Example 29, wherein the textile has a braided construction.

[0199] Example 35: Any example herein, particularly the textile of Example 34, wherein the braided construction is bi-axial, tri-axial, uni-axial, or a combination thereof.

[0200] Example 36: Any example herein, particularly the textile of Example 32 or 33, wherein there is no second yarn, and the weft direction of the textile includes the first yarn.

[0201] Example 37: Any example herein, particularly the textile of Example 36, wherein there is no second yarn, and the warp direction of the textile includes the one or more other yarns.

[0202] Example 38: Any example herein, particularly the textile of Example 36, wherein there is no second yarn, and the warp direction of the textile includes a combination of the one or more other yarns and the first yarn.

[0203] Example 39: Any example herein, particularly the textiles of Examples 32 or 33, in which there is a second yarn, and the warp direction of the textile includes multicomponent yarns in a ratio of about 1:2 to about 1:10 and the one or more other yarns.

[0204] Example 40: Any example herein, particularly the textile of Example 39, in which the warp direction of the textile further includes a third yarn different from the first yarn.

[0205] Example 41: Any example herein, particularly the textile of Example 40, in which the third yarn includes a third polymer, and the third polymer includes polyester, nylon, polyolefin, polyurethane, or a combination thereof.

[0206] Example 42: Any example herein, particularly the textiles of Examples 40 or 41, in which the third yarn includes a fully drawn yarn, a spun-drawn yarn, a low-twist or non-twisted yarn, a twisted yarn, a flat yarn, a texturized yarn, a high-bulk texturized yarn, a high-shrinkage yarn, or any combination thereof.

[0207] Example 43: Any example herein, particularly the textile of Example 42, in which the third yarn is a texturized yarn.

[0208] Example 44: Any example herein, particularly the textiles of Examples 39-43, in which there is a second yarn, and the weft direction of the textile includes the one or more other yarns.

[0209] Example 45: Any example herein, particularly the textiles of Examples 39-44, in which the multicomponent yarns are woven in the warp direction at a different tension from the one or more other yarns woven in the warp direction.

[0210] Example 46: Any example herein, particularly the textile of Example 45, in which the multicomponent yarns are woven in the warp direction at a higher tension than the one or more other yarns woven in the warp direction.

[0211] Example 47: Any example herein, particularly the textile of Example 45, in which the multicomponent yarns are woven in the warp direction at a lower tension than the one or more other yarns woven in the warp direction.

[0212] Example 48: Any example herein, particularly the textiles of Examples 39-47, in which the third yarn is woven in the warp direction separately from the multicomponent yarns and / or the one or more other yarns.

[0213] Example 49: Any example herein, particularly the textile of Example 48, in which, when compared to a substantially identical reference textile lacking the third yarn, the third yarn forms longer floats or a napped feature on the surface of the textile.

[0214] Example 50: Any example herein, particularly the textile of Example 49, wherein the textile has a higher surface area compared to a substantially identical reference textile lacking a third yarn.

[0215] Example 51: Any example herein, particularly the textiles of Examples 39 - 50, wherein the textile has a predetermined woven pattern including a multi - component yarn and said one or more other yarns arranged alternately side - by - side in the warp direction.

[0216] Example 52: Any example herein, particularly the textiles of Examples 39 - 51, wherein said one or more other yarns in the warp direction are texturized yarns, high - stretch (HS) texturized yarns, high - bulk texturized yarns, and / or high - shrinkage yarns.

[0217] Example 53: Any example herein, particularly the textiles of Examples 44 - 52, wherein said one or more other yarns in the weft direction are flat yarns or twisted yarns, texturized yarns, high - stretch (HS) texturized yarns, and / or high - bulk texturized yarns.

[0218] Example 54: Any example herein, particularly the textiles of Examples 39 - 53, wherein the warp density of the multi - component yarn is from about 10 warp yarns per inch to about 200 warp yarns per inch.

[0219] Example 55: Any example herein, particularly the textiles of Examples 51 - 54, wherein the warp density of said one or more other yarns including texturized yarns, high - stretch (HS) texturized yarns, high - bulk texturized yarns, and / or high - shrinkage yarns is from about 10 warp yarns per inch to about 200 warp yarns per inch.

[0220] Example 56: Any example herein, particularly the textiles of Examples 49 - 55, wherein the weft density is from about 10 weft yarns per inch to about 200 weft yarns per inch.

[0221] Example 57: Any example herein, particularly the textile of Example 31, wherein the textile does not include a second yarn and has a warp - knitted structure, and the warp direction of the textile includes a first yarn and said one or more other yarns in a ratio of about 1:2 to about 1:10.

[0222] Example 58: Any example herein, particularly the textile of Example 31, wherein the textile has a crocheted structure and the warp direction of the textile includes a first yarn.

[0223] Example 59: Any example herein, particularly the textile of Example 58, wherein the warp direction further includes said one or more other yarns in a ratio of about 1:2 to about 1:10.

[0224] Example 60: Any example herein, particularly the textile of Example 31, in which there is a second yarn and the textile has a warp-knit structure, and the warp direction of the textile includes multicomponent yarns in a ratio of about 1:2 to about 1:10 and the one or more other yarns.

[0225] Example 61: Any example herein, particularly the textiles of Examples 57 - 60, in which the weft direction of the textile includes the one or more other yarns.

[0226] Example 62: Any example herein, particularly the textile of Example 31, in which the textile does not include a second yarn and has a weft-knit structure, and the textile includes a first yarn and an inlay of the one or more other yarns.

[0227] Example 63: Any example herein, particularly the textiles of Examples 34 or 35, in which the knitted structure includes a core and a sheath.

[0228] Example 64: Any example herein, particularly the textile of Example 63, in which if there is no second yarn, the core of the knitted structure includes the first yarn and the sheath includes the one or more other yarns.

[0229] Example 65: Any example herein, particularly the textile of Example 63, in which there is a second yarn and the sheath includes multicomponent yarns.

[0230] Example 66: Any example herein, particularly the textile of Example 65, in which the knitted structure further includes other first yarns not covered by the second yarn, and the core includes the other first yarns.

[0231] Example 67: Any example herein, particularly the textiles of Examples 1 - 66, in which the textile exhibits an elastic recovery rate of at least about 80%.

[0232] Example 68: Any example herein, particularly the textiles of Examples 1 - 67, in which the textile exhibits high stretchability, self-conformability to a substrate, retention of a predetermined stitch, retention of a predetermined fabric density, retention of pore size, retention of thickness, or a combination thereof.

[0233] Example 69: An article comprising any example herein, particularly the textiles of Examples 1 - 68.

[0234] Example 70: Any example herein, particularly the article of Example 69, in which the article includes an implantable device.

[0235] Example 71: Any example herein, particularly the articles of Examples 69 - 70, in which the article is in substantial contact with an object's body and / or an object's body fluids.

[0236] Example 72: A medical device, including any example herein, particularly the textiles of Examples 1-66.

[0237] Example 73: Any example herein, particularly the medical device of Example 72, wherein the device is implantable.

[0238] Example 74: Any example herein, particularly the medical devices of Examples 72-73, wherein the device is configured to be inserted into a subject's body.

[0239] Example 75: A method, including forming a textile that includes: a) a first yarn including one or more filaments that include a first polymer; b) one or more other yarns having a composition and / or properties different from the first yarn; and c) optionally a second yarn including one or more filaments that include a second polymer, wherein if the second yarn is present, the second yarn coats the first yarn to form a multicomponent yarn such that the first yarn forms a core and the second yarn forms a sheath, wherein the first yarn exhibits a higher elasticity than the elasticity of the one or more other yarns and, if the second yarn is present, the elasticity of the second yarn; and wherein the textile exhibits an ultimate elongation of from about 50% to about 700% and has shape adaptability and biocompatibility and is configured to be inserted and / or implanted into a subject's body.

[0240] Example 76: Any example herein, particularly the method of Example 75, wherein the multicomponent yarn is formed by coating the second yarn around the first yarn.

[0241] Example 77: Any example herein, particularly the methods of Examples 75-76, wherein the first polymer includes thermoplastic polyurethane (TPU), polyurethane (PU), thermoplastic elastomer (TPE), elastomeric polyolefin, polybutylene terephthalate (PBT), silicone-based elastomer, or a combination thereof.

[0242] Example 78: Any example herein, particularly the methods of Examples 75-77, wherein the hardness of the first polymer is from about 75A to about 75D.

[0243] Example 79: Any example herein, particularly the methods of Examples 75-78, wherein the ultimate tensile strength of the first polymer is between about 4500 psi and about 8000 psi.

[0244] Example 80: Any example herein, particularly the methods of Examples 75-79, wherein the ultimate elongation of the first polymer is between about 50% and about 700%.

[0245] Example 81: Any example herein, particularly the methods of Examples 75-80, wherein the first polymer is TPU.

[0246] Example 82: Any example herein, particularly the methods of Examples 75 - 81, wherein the first yarn is a monofilament.

[0247] Example 83: Any example herein, particularly the methods of Examples 75 - 81, wherein the first yarn is a multifilament.

[0248] Example 84: Any example herein, particularly the method of Example 83, wherein the filament count of the first yarn is greater than about 1 to about 50.

[0249] Example 85: Any example herein, particularly the methods of Examples 75 - 84, wherein the fineness of one or more filaments of the first yarn ranges from about 5 denier to about 1000 denier.

[0250] Example 86: Any example herein, particularly the methods of Examples 75 - 85, wherein if there are more than one other yarns, these other yarns are the same or different.

[0251] Example 87: Any example herein, particularly the methods of Examples 75 - 86, wherein the one or more other yarns include fully drawn yarn, spun - drawn yarn, low - twist or non - twist yarn, twisted yarn, flat yarn, texturized yarn, high - stretch (HS) texturized yarn, high - bulk texturized yarn, high - shrinkage yarn, or any combination thereof.

[0252] Example 88: Any example herein, particularly the methods of Examples 75 - 87, wherein the one or more other yarns include polyolefin, polyester, polyurethane, thermoplastic polyurethane, polyamide, or a combination thereof.

[0253] Example 89: Any example herein, particularly the methods of Examples 75 - 88, wherein the one or more other yarns are substantially rigid or semi - rigid.

[0254] Example 90: Any example herein, particularly the methods of Examples 75 - 89, wherein when a second yarn is present, the elasticity of the first polymer is higher than that of the second polymer.

[0255] Example 91: Any example herein, particularly the methods of Examples 75 - 90, wherein when a second yarn is present, the second polymer includes polyester, nylon, polyolefin, or a combination thereof.

[0256] Example 92: Any example herein, particularly the method of Example 91, wherein the second polymer includes polyethylene terephthalate (PET) homopolymers and copolymers, polypropylene terephthalate (PPT) homopolymers and copolymers, and polybutylene terephthalate (PBT) homopolymers and copolymers, or any combination thereof.

[0257] Example 93: Any example herein, particularly the methods of Examples 75-92, wherein when a second yarn is present, the second yarn is a monofilament.

[0258] Example 94: Any example herein, particularly the methods of Examples 75-92, wherein a second yarn is present and the second yarn is a multifilament.

[0259] Example 95: Any example herein, particularly the method of Example 94, wherein the filament count of the second yarn is greater than 1 to about 150.

[0260] Example 96: Any example herein, particularly the methods of Examples 75-95, wherein when a second yarn is present, the fineness of one or more filaments of the second yarn ranges from about 5 denier to about 1000 denier.

[0261] Example 97: Any example herein, particularly the methods of Examples 75-96, wherein the multicomponent yarn, if present, is single-covered or double-covered.

[0262] Example 98: Any example herein, particularly the method of Example 97, wherein the multicomponent yarn is double-covered and two second yarns cover the first yarn in opposite directions.

[0263] Example 99: Any example herein, particularly the methods of Examples 75-98, wherein the second yarn comprises a fully drawn yarn, a spun-drawn yarn, a low-twist or non-twisted yarn, a twisted yarn, a flat yarn, a textured yarn, a high-stretch (HS) textured yarn, a high-bulk textured yarn, a high-shrinkage yarn, or any combination thereof.

[0264] Example 100: Any example herein, particularly the methods of Examples 75-99, wherein one or more filaments of the first yarn are melt-spun.

[0265] Example 101: Any example herein, particularly the methods of Examples 75-100, wherein the forming step comprises weaving, knitting, or braiding.

[0266] Example 102: Any example herein, particularly the method of Example 101, wherein the textile is formed by weaving and the second yarn is absent, and the first yarn is woven in the weft direction.

[0267] Example 103: Any example herein, particularly the method of Example 102, wherein the one or more other yarns are woven in the warp direction.

[0268] Example 104: Any example herein, particularly the method of Example 102, wherein the one or more other yarns and the first yarn are woven in the warp direction.

[0269] Example 105: Any example herein, particularly the method of Example 101, wherein the textile is formed by weaving and there is a second yarn, the multi-component yarn is mounted on a first warp beam, and wherein said one or more other yarns are mounted on a second warp beam such that the first warp beam is under a different tension than the second warp beam.

[0270] Example 106: Any example herein, particularly the method of Example 105, wherein the first warp beam is under a higher tension than the second warp beam.

[0271] Example 107: Any example herein, particularly the method of Example 105, wherein the first warp beam is under a lower tension than the second warp beam.

[0272] Example 108: Any example herein, particularly the method of Examples 105 - 107, wherein the warp direction of the textile comprises multi-component yarn and said one or more other yarns in a ratio of from about 1:2 to about 1:10.

[0273] Example 109: Any example herein, particularly Examples 105 - 108, further comprising a third warp beam, the third warp beam comprising a third yarn different from the first yarn.

[0274] Example 110: Any example herein, particularly the method of Example 109, wherein the third yarn comprises a fully drawn yarn, a spun-drawn yarn, a low-twist or non-twisted yarn, a twisted yarn, a flat yarn, a textured yarn, a high-stretch (HS) textured yarn, a high-bulk textured yarn, a high-shrinkage yarn, or any combination thereof.

[0275] Example 111: Any example herein, particularly the method of Example 110, wherein the third yarn is a textured yarn.

[0276] Example 112: Any example herein, particularly the method of Examples 105 - 111, wherein the weft direction of the textile comprises said one or more other yarns.

[0277] Example 113: Any example herein, particularly the method of Examples 109 - 112, wherein the third yarn forms a longer float or a napped feature on the surface of the textile when compared to a substantially identical reference textile lacking the third yarn.

[0278] Example 114: Any example herein, particularly the method of Example 113, wherein the textile has a higher surface area when compared to a substantially identical reference textile lacking the third yarn.

[0279] Example 115: Any example herein, particularly the methods of Examples 105 - 114, where the textile has a predetermined woven pattern, including multi - component yarns arranged alternately side - by - side with said one or more other yarns along the warp direction.

[0280] Example 116: Any example herein, particularly the methods of Examples 105 - 115, where said one or more other yarns along the warp direction are textured yarns, high - stretch (HS) textured yarns, high - bulk textured yarns, and / or high - shrinkage yarns.

[0281] Example 117: Any example herein, particularly the methods of Examples 112 - 116, where said one or more other yarns along the weft direction are flat yarns or twisted yarns or textured yarns.

[0282] Example 118: Any example herein, particularly the methods of Examples 104 - 117, where the warp density of the multi - component yarn is from about 10 warps per inch to about 200 warps per inch.

[0283] Example 119: Any example herein, particularly the methods of Examples 112 - 116, where the warp density of the textured yarns, high - bulk textured yarns, and / or high - shrinkage yarns is from about 10 warps per inch to about 200 warps per inch.

[0284] Example 120: Any example herein, particularly the methods of Examples 112 - 119, where the weft density is from about 10 wefts per inch to about 200 wefts per inch.

[0285] Example 121: Any example herein, particularly the methods of Examples 101 - 120, where the forming step is weaving, and the textile can be a woven structure, including plain weave, derivatives of plain weave, double - plain weave, basket weave, twill weave, satin weave, dobby weave, jacquard weave, extra - yarn weave, raised - pattern weave, double - layer fabric textile, crepe weave, leno weave, pile weave, triaxial weave, or a combination thereof.

[0286] Example 122: Any example herein, particularly the methods of Examples 101 - 121, where the textile includes a simple single - jersey knitted structure; a single - jersey knitted and knit - float pattern structure; a single - jersey knitted and knit - tuck pattern structure; tricot warp - knitted, plain - velvet warp - knitted, satin - knitted, velvet - warp - knitted, twill - warp - knitted, purl - knitted, rib - knitted, lock - stitch double - ribbed, double - knitted, warp - knitted, raschel - knitted corded pattern, bird's - eye - patterned knitted, pontell - knitted, intarsia - knitted, jacquard - knitted, terry - knitted textile, knitted velvet textile, wool - fed knitted, fleece - knitted, or any combination thereof.

[0287] Example 123: Any example herein, particularly the method of Example 122, wherein the textile is formed by knitting and wherein the textile does not include a second yarn and has a warp knitting construction, and wherein the warp direction of the textile includes a first yarn and said one or more other yarns in a ratio of from about 1:2 to about 1:10.

[0288] Example 124: Any example herein, particularly the method of Example 122, wherein the textile is formed by knitting and wherein the textile has a crochet construction, and wherein the warp direction of the textile includes a first yarn.

[0289] Example 125: Any example herein, particularly the method of Example 124, wherein the warp direction further includes said one or more other yarns in a ratio of from about 1:2 to about 1:10.

[0290] Example 126: Any example herein, particularly the method of Example 122, wherein the textile is formed by knitting and wherein there is a second yarn and the textile has a warp knitting construction, and wherein the warp direction of the textile includes a multicomponent yarn and said one or more other yarns in a ratio of from about 1:2 to about 1:10.

[0291] Example 127: Any example herein, particularly the methods of Examples 123 - 126, wherein the weft direction of the textile includes said one or more other yarns.

[0292] Example 128: Any example herein, particularly the method of Example 122, wherein the textile is formed by knitting and wherein the textile does not include a second yarn and has a weft knitting construction, and the textile includes a first yarn and a laid-in yarn of said one or more other yarns.

[0293] Example 129: Any example herein, particularly the method of Example 101, wherein the forming step includes weaving to form a woven construction.

[0294] Example 130: Any example herein, particularly the method of Example 129, wherein the woven construction includes a core and a skin.

[0295] Example 131: Any example herein, particularly the method of Example 130, wherein if there is no second yarn, the core of the woven construction includes the first yarn and the skin includes said one or more other yarns.

[0296] Example 132: Any example herein, particularly the method of Example 131, wherein there is a second yarn and the skin includes a multicomponent yarn.

[0297] Example 133: Any example herein, particularly the method of Example 132, wherein the braided structure further comprises other first yarns not covered by the second yarn, and wherein the core comprises the other first yarns.

[0298] Example 134: Any example herein, particularly the methods of Examples 129 - 133, wherein the braided structure is biaxial, triaxial, unidirectional, or a combination thereof.

[0299] Example 135: Any example herein, particularly the methods of Examples 75 - 134, wherein the textile exhibits an elastic recovery rate of at least 80%.

[0300] Example 136: Any example herein, particularly the methods of Examples 75 - 135, wherein the textile exhibits high stretchability, self - adaptability to the substrate, maintaining a predetermined suture, maintaining a predetermined fabric density, maintaining pore size, maintaining thickness, or a combination thereof.

[0301] Example 137: An implantable prosthetic valve, comprising: an annular frame having an inflow end, an outflow end, and a longitudinal axis; and a sealing element fixed to the frame, wherein the sealing element comprises any example herein, particularly the textile of Examples 1 - 68.

[0302] Example 138: An implantable prosthetic valve, comprising: an annular frame having an inflow end, an outflow end, and a longitudinal axis, wherein the annular frame is configured to expand and contract; and a sealing element fixed to the frame, wherein the sealing element comprises a textile, the textile comprising: a) a first yarn comprising one or more filaments, the filaments comprising a first polymer; b) one or more other yarns comprising a composition and / or properties different from the first yarn; wherein the first yarn exhibits higher elasticity than the one or more other yarns, wherein the textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility, and wherein the textile is configured to be inserted and / or implanted into the body of an object.

[0303] Example 139: Any example herein, particularly the implantable prosthetic valve of Example 138, wherein the textile further comprises a second yarn, the second yarn comprising one or more filaments comprising a second polymer, the second polymer comprising polyester, nylon, polyolefin, or a combination thereof, and wherein the second yarn is different from the first yarn, wherein the first polymer has higher elasticity than the second polymer; wherein the second yarn covers the first yarn to form a multi - component yarn such that the first yarn forms a core and the second yarn forms a sheath, wherein the multi - component yarn is single - covered or double - covered, and wherein when the multi - component yarn is double - covered, two second yarns cover the first yarn in opposite directions.

[0304] Example 140: Any example herein, particularly the implantable prosthetic valve of Example 138 or 139, wherein the sealing element is an outer skirt configured to establish a seal against the patient's native tissue.

[0305] Example 141: Any example herein, particularly the implantable prosthetic valve of Examples 138 - 140, wherein the sealing element is attached to the annular frame by fasteners.

[0306] Although several aspects of the present disclosure have been disclosed in the foregoing specification, those skilled in the art will understand that many modifications and other aspects of the present disclosure will occur to those skilled in the art to which the present disclosure pertains, upon benefiting from the foregoing description and the teachings presented in the related drawings. Accordingly, it is to be understood that the present disclosure is not limited to the specific aspects disclosed above, and that many modifications and other aspects are intended to be included within the scope of the appended claims. Additionally, although specific terms are used herein and in the appended claims, they are used only in a generic and descriptive sense and not for the purpose of limiting the disclosed subject matter or the appended claims. Thus, we claim all that falls within the scope and spirit of these claims as our disclosure.

Claims

1. A textile, comprising: a) a first yarn comprising one or more filaments, said filaments comprising a first polymer; b) one or more other yarns having a composition and / or properties different from those of said first yarn, wherein said one or more other yarns comprise polyolefin, polyester, polyurethane, thermoplastic polyurethane, polyamide, or a combination thereof; c) optionally a second yarn comprising one or more filaments, said filaments comprising a second polymer, wherein if said second yarn is present, said second yarn coats said first yarn to form a multicomponent yarn such that said first yarn forms a core and said second yarn forms a sheath; wherein said first yarn exhibits higher elasticity than the elasticity of said one or more other yarns, wherein said textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility, wherein said textile is configured to be inserted and / or implanted into the body of an object, wherein said textile has a knitted structure or a woven structure, and wherein: when said second yarn is absent, the weft direction of said textile comprises said first yarn and / or the warp direction of said textile comprises said one or more other yarns; or when said second yarn is present, the warp direction of said textile comprises said multicomponent yarn and said one or more other yarns in a ratio of about 1:2 to about 1:

10.

2. The textile according to claim 1, wherein said first polymer comprises thermoplastic polyurethane (TPU), polyurethane (PU), thermoplastic elastomer (TPE), elastomeric polyolefin, polybutylene terephthalate (PBT), silicone-based elastomer, or a combination thereof; and / or wherein the hardness of said first polymer is about 75A to about 75D and / or wherein the ultimate tensile strength of said first polymer is between about 4500 psi and about 8000 psi.

3. The textile according to any one of claims 1-2, wherein the fineness of one or more filaments of said first yarn ranges from about 5 denier to about 1000 denier.

4. The textile according to any one of claims 1-2, wherein there are more than one other yarns, which are the same or different and comprise fully drawn yarn, spun-drawn yarn, low twist or non-twist yarn, twisted yarn, flat yarn, textured yarn, high stretch (HS) textured yarn, high bulk textured yarn, high shrinkage yarn, or any combination thereof.

5. The textile according to any one of claims 1-2, further comprising a second yarn, said second yarn comprising one or more filaments comprising a second polymer, said second polymer comprising polyester, nylon, polyolefin, or a combination thereof, and wherein said second yarn is different from said first yarn, wherein the elasticity of said first polymer is higher than that of said second polymer, and wherein the fineness of one or more filaments of said second yarn ranges from about 5 denier to about 1000 denier.

6. The textile according to claim 5, wherein said second yarn coats said first yarn to form a multicomponent yarn such that said first yarn forms a core and said second yarn forms a sheath.

7. The textile according to claim 6, wherein the multicomponent yarn is single-covered or double-covered, and wherein when the multicomponent yarn is double-covered, two second yarns cover the first yarn in opposite directions.

8. The textile according to claim 5, wherein the second yarn comprises a fully drawn yarn, a spun-drawn yarn, a low-twist or non-twisted yarn, a twisted yarn, a flat yarn, a textured yarn, a high-stretch (HS) textured yarn, a high-bulk textured yarn, a high-shrinkage yarn, or any combination thereof.

9. The textile according to any one of claims 1-2 and 6-7, wherein one or more filaments of the first yarn are melt-spun.

10. The textile according to any one of claims 1-2 and 6-7, wherein the textile has: i) a knitted structure and includes a simple single-sided Jersey knit structure; a single-sided Jersey knit and a knit-float pattern structure; a single-sided Jersey knit and a knit-tuck pattern structure; a tricot warp knit, a plain jersey stitch, a satin knit, a warp jersey stitch, a warp twill stitch, a purl stitch, a rib stitch, a lockstitch double rib stitch, a double-sided knit, a warp knit, a Raschel knit corded pattern, an eyelet knit, a pontell knit, an intarsia knit, a jacquard knit, a terry knit textile, a knitted velvet textile, a top-fed knit, a napped knit, a warp knit, a weft knit or a crocheted structure, or any combination thereof; or ii) a woven structure, including a plain weave, a derivative of a plain weave, a double plain weave, a basket weave, a twill weave, a satin weave, a dobby weave, a jacquard weave, a special yarn weave, a raised weave, a double-layer fabric textile, a crepe weave, a leno weave, a pile weave, a triaxial weave, or a combination thereof.

11. The textile according to claim 1, wherein when the second yarn is present, the warp direction of the woven textile further comprises a third yarn different from the first yarn, and wherein the third yarn comprises a third polymer, the third polymer comprising polyester, nylon, polyolefin, polyurethane, or a combination thereof; and wherein the third yarn comprises a fully drawn yarn, a spun-drawn yarn, a low-twist or non-twisted yarn, a twisted yarn, a flat yarn, a textured yarn, a high-bulk textured yarn, a high-shrinkage yarn, or any combination thereof.

12. The textile according to any one of claims 1-2, wherein the multicomponent yarn is woven in the warp direction at a tension different from the tension of the one or more other yarns woven in the warp direction.

13. The textile according to claim 11, wherein the third yarn is woven in the warp direction separately from the multicomponent yarn and / or the one or more other yarns, and wherein when compared to a substantially identical reference textile lacking the third yarn, the third yarn forms a longer float length or a napped feature on the surface of the textile, and wherein the textile has a higher surface area when compared to a substantially identical reference textile lacking the third yarn.

14. The textile according to any one of claims 1 - 2, wherein the warp density of the multi - component yarn is from about 10 warps per inch to about 200 warps per inch; and / or wherein the warp density of the one or more other yarns comprising textured yarn, high - stretch (HS) textured yarn, and / or high - bulk textured yarn is from about 10 warps per inch to about 200 warps per inch.

15. The textile according to claim 11, wherein the weft density is from about 10 wefts per inch to about 200 wefts per inch.

16. The textile according to claim 10, wherein when the textile does not include the second yarn and has a warp - knitted structure, the warp direction of the textile comprises the first yarn and the one or more other yarns in a ratio of about 1:2 to about 1:10; or when the textile has a crocheted structure, the warp direction of the textile comprises the first yarn, and wherein the warp direction further comprises the one or more other yarns in a ratio of about 1:2 to about 1:10; or when the second yarn is present and the textile has a warp - knitted structure, the warp direction of the textile comprises the multi - component yarn and the one or more other yarns in a ratio of about 1:2 to about 1:10; or when the textile does not include the second yarn and has a weft - knitted structure, the textile comprises an inlay of the first yarn and the one or more other yarns.

17. The textile according to any one of claims 1 - 2, 6 - 7, 11, 13, and 15 - 16, wherein the textile exhibits an elastic recovery rate of at least 80%.

18. The textile according to any one of claims 1 - 2, 6 - 7, 11, 13, and 15 - 16, wherein the textile exhibits high stretchability, self - conformability to a substrate, retention of a predetermined stitch, retention of a predetermined fabric density, retention of pore size, retention of thickness, or a combination thereof.

19. A method, comprising: forming a textile, the textile comprising: a) a first yarn comprising one or more filaments, the filaments comprising a first polymer; b) one or more other yarns having a composition and / or properties different from those of the first yarn, wherein the one or more other yarns comprise polyolefin, polyester, polyurethane, thermoplastic polyurethane, polyamide, or a combination thereof; and c) optionally a second yarn comprising one or more filaments, the filaments comprising a second polymer, wherein if the second yarn is present, the second yarn coats the first yarn to form a multi - component yarn such that the first yarn forms a core and the second yarn forms a sheath; wherein the first yarn exhibits higher elasticity than the one or more other yarns and, if the second yarn is present, higher elasticity than the second yarn; wherein the textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility, and is configured to be inserted and / or implanted into the body of an object, wherein the textile has a knitted structure or a woven structure, and wherein: When the second yarn is absent, the weft direction of the textile includes the first yarn and / or the warp direction of the textile includes the one or more other yarns; or When the second yarn is present, the warp direction of the textile includes the multicomponent yarn and the one or more other yarns in a ratio of about 1:2 to about 1:

10.

20. An implantable prosthetic valve, comprising: an annular frame having an inflow end, an outflow end, and a longitudinal axis; wherein the annular frame is configured to expand and contract; and a sealing element fixed to the frame, wherein the sealing element comprises a textile having a knitted, woven, or braided structure and comprising: i) a first yarn comprising one or more filaments comprising a first polymer; ii) one or more other yarns having a composition and / or properties different from those of the first yarn, wherein the one or more other yarns comprise polyolefin, polyester, polyurethane, thermoplastic polyurethane, polyamide, or a combination thereof; iii) optionally a second yarn comprising one or more filaments comprising a second polymer, wherein if the second yarn is present, the second yarn coats the first yarn to form a multicomponent yarn such that the first yarn forms a core and the second yarn forms a sheath; wherein the first yarn exhibits higher elasticity than the one or more other yarns; wherein the textile exhibits an ultimate elongation of about 50% to about 700% and has shape adaptability and biocompatibility, wherein the textile is configured to be inserted and / or implanted into the body of a subject, wherein the textile has a knitted structure or a woven structure, and wherein: When the second yarn is absent, the weft direction of the textile includes the first yarn and / or the warp direction of the textile includes the one or more other yarns; or When the second yarn is present, the warp direction of the textile includes the multicomponent yarn and the one or more other yarns in a ratio of about 1:2 to about 1:

10.

21. The implantable prosthetic valve according to claim 20, wherein the textile further comprises a second yarn comprising one or more filaments comprising a second polymer, the second polymer comprising polyester, nylon, polyolefin, or a combination thereof, and wherein the second yarn is different from the first yarn, wherein the first polymer has higher elasticity than the second polymer; wherein the second yarn coats the first yarn to form a multicomponent yarn such that the first yarn forms a core and the second yarn forms a sheath, wherein the multicomponent yarn is single-coated or double-coated, and wherein when the multicomponent yarn is double-coated, two second yarns coat the first yarn in opposite directions.

22. The implantable prosthetic valve according to claim 20 or 21, wherein the sealing element is an outer skirt configured to establish a seal against the patient's native tissue.

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