Medical image processing method and device, computer device and storage medium

Abstract

The application relates to a medical image processing method and device, computer equipment, a storage medium and a computer program product. The method comprises the following steps: acquiring a coil MR image corresponding to an MR coil, and acquiring a CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on a target scanning object wearing the MR coil; the coil MR image and the CT coil attenuation map are registered to obtain a target attenuation map; and the PET data corresponding to the target scanning object wearing the MR coil are subjected to attenuation correction through the target attenuation map to obtain a reconstructed PET image. The method can improve the accuracy of the reconstructed PET image.

Description

Technical Field

[0001] This application relates to the field of image processing technology, and in particular to a medical image processing method, apparatus, computer equipment, storage medium, and computer program product. Background Technology

[0002] In recent years, with the continuous development of medical technology, medical imaging systems have become increasingly mature. Common medical imaging systems include single-modal imaging systems or multi-modal imaging systems, such as positron emission tomography (PET) systems, computed tomography (CT) systems, and magnetic resonance imaging (MR) systems, or multi-modal imaging systems such as PET / CT and PET / MR.

[0003] During PET imaging, the scattering and signal attenuation of 511 keV photons are physical effects that reduce the quantitative accuracy of PET images. In PET / MR imaging, the MR coil is an easily overlooked source of attenuation; therefore, attenuation correction of the MR coil is necessary to improve the quality of PET images.

[0004] Related techniques often use coil marking to correct MR coil attenuation. The coil marking method requires adding additional markers to locate the coil in order to establish a spatial correspondence between the markers in the attenuation map and their physical location. This may occur in some MR studies and may interfere with MR clinical quantitative parameters. Furthermore, since MR coils do not have a fixed position and shape during multiple scanning tasks, this attenuation correction method, which relies on the correspondence between a very small number of points placed outside the coil, cannot accurately correct attenuation, thus reducing the accuracy of the final reconstructed PET image.

[0005] Therefore, the relevant technologies suffer from low accuracy of reconstructed PET images during PET / MR scanning imaging. Summary of the Invention

[0006] Therefore, it is necessary to provide a medical image processing method, apparatus, computer equipment, computer-readable storage medium, and computer program product that can improve the accuracy of reconstructed PET images in response to the above-mentioned technical problems.

[0007] Firstly, this application provides a medical image processing method. The method includes:

[0008] Obtain the coil MR image corresponding to the MR coil, and obtain the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on the target object wearing the MR coil;

[0009] The MR image of the coil and the attenuation map of the CT coil are registered to obtain the target attenuation map;

[0010] The PET data corresponding to the target scanning object wearing the MR coil is attenuated by the target attenuation map to obtain the reconstructed PET image.

[0011] In one embodiment, registering the coil MR image and the CT coil attenuation map to obtain a target attenuation map includes:

[0012] The coil MR image and the CT coil attenuation map are registered to obtain the registered coil attenuation map.

[0013] The target attenuation map is obtained based on the object body attenuation map corresponding to the target scanning object and the coil attenuation map.

[0014] In one embodiment, the magnetic resonance sequence for the magnetic resonance scan is a dual-echo magnetic resonance sequence; acquiring the coil MR image corresponding to the MR coil includes:

[0015] A first MR image corresponding to the first echo signal of the dual-echo magnetic resonance sequence and a second MR image corresponding to the second echo signal of the dual-echo magnetic resonance sequence are acquired; the echo time of the first echo signal is shorter than the echo time of the second echo signal; the first MR image includes the MR coil and the target scanning object; the second MR image includes the target scanning object.

[0016] Based on the second MR image, the MR coil is identified in the first MR image to obtain the MR image of the coil.

[0017] In one embodiment, the step of identifying the MR coil in the first MR image based on the second MR image to obtain the MR image of the coil includes:

[0018] The first MR image and the second MR image are binarized respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image.

[0019] Subtract the first MR mask image from the second MR mask image to obtain the subtracted MR mask image;

[0020] The subtracted MR mask image is used as the coil MR image.

[0021] In one embodiment, obtaining the target attenuation map based on the object body attenuation map corresponding to the target scanning object and the coil attenuation map includes:

[0022] The second MR image is used as the object body MR image corresponding to the target scan object;

[0023] Based on the MR image of the object body, determine the attenuation map of the object body;

[0024] The target attenuation map is obtained by adding the attenuation map of the object body and the attenuation map of the coil.

[0025] In one embodiment, the MR coil is a dual-sided MR coil; the registration of the MR image of the coil and the attenuation map of the CT coil to obtain the registered coil attenuation map includes:

[0026] Obtain the first coil MR image and the second coil MR image corresponding to the coil MR image; the first coil MR image and the second coil MR image are images on both sides of the central axis of the MR coil in the coil MR image;

[0027] The CT coil attenuation map and the first coil MR image are registered to obtain the registered first CT coil attenuation map.

[0028] The CT coil attenuation map and the second coil MR image are registered to obtain the registered second CT coil attenuation map.

[0029] The coil attenuation map is obtained based on the registered first CT coil attenuation map and the registered second CT coil attenuation map.

[0030] In one embodiment, registering the coil MR image and the CT coil attenuation map to obtain a registered coil attenuation map includes:

[0031] Rigid registration is performed on the CT coil attenuation map and the coil MR image to obtain the CT coil attenuation map to be optimized;

[0032] The coil attenuation map is obtained by non-rigid registration of the CT coil attenuation map to be optimized and the coil MR image.

[0033] Secondly, this application also provides a medical image processing apparatus. The apparatus includes:

[0034] The acquisition module is used to acquire the coil MR image corresponding to the MR coil, and to acquire the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on a target object wearing the MR coil.

[0035] The registration module is used to register the coil MR image and the CT coil attenuation map to obtain the target attenuation map;

[0036] The correction module is used to perform attenuation correction on the PET data corresponding to the target scanning object wearing the MR coil using the target attenuation map, so as to obtain the reconstructed PET image.

[0037] Thirdly, this application also provides a computer device. The computer device includes a memory and a processor, the memory storing a computer program, and the processor executing the computer program to perform the following steps:

[0038] Obtain the coil MR image corresponding to the MR coil, and obtain the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on the target object wearing the MR coil;

[0039] The MR image of the coil and the attenuation map of the CT coil are registered to obtain the target attenuation map;

[0040] The PET data corresponding to the target scanning object wearing the MR coil is attenuated by the target attenuation map to obtain the reconstructed PET image.

[0041] Fourthly, this application also provides a computer-readable storage medium. The computer-readable storage medium stores a computer program thereon, which, when executed by a processor, performs the following steps:

[0042] Obtain the coil MR image corresponding to the MR coil, and obtain the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on the target object wearing the MR coil;

[0043] The MR image of the coil and the attenuation map of the CT coil are registered to obtain the target attenuation map;

[0044] The PET data corresponding to the target scanning object wearing the MR coil is attenuated by the target attenuation map to obtain the reconstructed PET image.

[0045] Fifthly, this application also provides a computer program product. The computer program product includes a computer program that, when executed by a processor, performs the following steps:

[0046] Obtain the coil MR image corresponding to the MR coil, and obtain the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on the target object wearing the MR coil;

[0047] The MR image of the coil and the attenuation map of the CT coil are registered to obtain the target attenuation map;

[0048] The PET data corresponding to the target scanning object wearing the MR coil is attenuated by the target attenuation map to obtain the reconstructed PET image.

[0049] The aforementioned medical image processing method, apparatus, device, storage medium, and computer program product acquire an MR image corresponding to an MR coil and an attenuation map of a CT coil corresponding to the MR coil. The MR image is obtained by performing magnetic resonance scanning on a target object wearing an MR coil. The MR image and the CT coil attenuation map are registered to obtain a target attenuation map. The PET data corresponding to the target object wearing an MR coil is attenuated using the target attenuation map to obtain a reconstructed PET image.

[0050] Thus, in PET / MR scanning imaging, by performing magnetic resonance scanning on a target object wearing an MR coil to obtain the coil's MR image, the MR coil can be located in the field of view (FOV). Then, by registering the pre-acquired CT coil attenuation map corresponding to the MR coil with the coil's MR image, the actual deformation of the MR coil can be accurately captured during registration. Therefore, the registered target attenuation map matches the deformation field information of the MR coil. In PET / MR scanning imaging of a target object wearing an MR coil, the attenuation information of the MR coil can be accurately obtained based on the target attenuation map. This allows for accurate correction of attenuation and scattering caused by the MR coil during the attenuation correction of the PET data corresponding to the target object based on the target attenuation map, resulting in a highly accurate reconstructed PET image. This solves the problem of poor correction accuracy in PET / MR scanning imaging caused by the non-fixed position and shape of the MR coil during the scanning task, which necessitates the use of fixed attenuation maps or reliance on the correspondence between a very small number of points placed outside the coil for attenuation correction. Consequently, in PET / MR scanning imaging of a target object wearing an MR coil, the quantitative accuracy of PET is improved, resulting in a more accurate reconstructed PET image. Attached Figure Description

[0051] Figure 1 This is a flowchart illustrating a medical image processing method in one embodiment;

[0052] Figure 2This is a flowchart illustrating the steps for obtaining the MR image of the MR coil corresponding to one embodiment.

[0053] Figure 3 This is a flowchart illustrating the steps for obtaining the registered coil attenuation map in one embodiment;

[0054] Figure 4 This is a flowchart illustrating the steps for obtaining a target attenuation map in one embodiment;

[0055] Figure 5 This is a flowchart illustrating a medical image processing method in another embodiment;

[0056] Figure 6 This is a flowchart of an attenuation correction method for a target scanning object wearing an MR coil, as described in one embodiment.

[0057] Figure 7 This is a structural block diagram of a medical image processing device in one embodiment;

[0058] Figure 8 This is an internal structural diagram of a computer device in one embodiment. Detailed Implementation

[0059] To make the objectives, technical solutions, and advantages of this application clearer, the following detailed description is provided in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application.

[0060] It should be noted that the terms "first," "second," etc., used in the specification, claims, and accompanying drawings of this disclosure are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this disclosure described herein can be implemented in orders other than those illustrated or described herein. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with this disclosure. Rather, they are merely examples of apparatuses and methods consistent with some aspects of this disclosure as detailed in the appended claims.

[0061] Over the past few decades, PET imaging has been widely used for tumor staging and grading, preoperative assessment, and prognostic evaluation. Traditional techniques typically utilize attenuation correction based on atlases; however, conventional attenuation correction based on atlases neglects the impact of MR coils on PET quantification. Designing non-attenuating MR coils has proven difficult, and even PET-optimized coils can introduce significant quantitative errors in human studies. Therefore, attenuation correction for these coils, currently not included in standard system reconstruction, is crucial for accurate PET quantification. Successful attenuation correction of MR hardware and coils requires the availability of an attenuation map containing the correct attenuation factor for the object. Furthermore, for such an attenuation map to be applied, the object must be precisely positioned within the field of view (FOV). For rigid MR coils, including head and neck coils or spinal coils, their position within the FOV is static, allowing the use of static attenuation maps to correct their attenuation. On the other hand, flexible surface coils change their position and shape between imaging sessions, making fixed attenuation maps an impractical solution. The use of MR imaging can be employed to detect the position of flexible coils and other MR hardware within the FOV, allowing for the registration of pre-calculated attenuation maps. This positioning can be achieved by placing MR visible reference markers on the outer surface of the coil, or by directly imaging some components of the coil using specialized sequences such as ultrashort echo time series (UTE).

[0062] Based on this, this application provides a medical image processing method for improving the accuracy of reconstructed PET images, which can be applied to computer devices equipped with integrated medical imaging systems (including single-modal imaging systems and multimodal hybrid imaging systems). The integrated medical imaging system may include PET / MR systems, PET / CT systems, CT systems, etc., and is not limited thereto. The computer device can be implemented as part or all of a computer device through software, hardware, or a combination of both. In the following method embodiments, the execution subject is always described using a computer device as an example.

[0063] In one embodiment, such as Figure 1 As shown, a medical image processing method is provided, including the following steps:

[0064] Step S110: Obtain the MR image of the MR coil corresponding to the MR coil, and obtain the CT coil attenuation map corresponding to the MR coil.

[0065] Among them, the coil MR image is obtained by performing magnetic resonance scanning on a target object wearing an MR coil.

[0066] Among them, the CT coil attenuation map is the attenuation map corresponding to the MR coil obtained from the CT image corresponding to the MR coil.

[0067] The target object to be scanned can be a living organism (such as a human or an animal).

[0068] Among them, the MR coil can be a human body coil or an animal coil.

[0069] In practice, the computer equipment can obtain the CT coil attenuation map corresponding to the MR coil. At the same time, after the MR module in the PET / MR system performs magnetic resonance scanning on the target object wearing the MR coil, the computer equipment can obtain the coil MR image corresponding to the MR coil.

[0070] Step S120: Register the coil MR image and the CT coil attenuation map to obtain the target attenuation map.

[0071] In practice, computer equipment can register the coil MR image and the CT coil attenuation map to obtain the target attenuation map corresponding to the target scanning object wearing the MR coil.

[0072] Step S130: Attenuation correction is performed on the PET data corresponding to the target scanning object wearing the MR coil using the target attenuation map to obtain the reconstructed PET image.

[0073] The PET data was obtained by scanning a target object wearing an MR coil using the PET module in a PET / MR system.

[0074] Among them, the PET data and coil MR images are obtained by the PET / MR system simultaneously performing PET and MR scans on the target object wearing an MR coil.

[0075] In practice, the computer device can perform attenuation correction on the PET data corresponding to the target scanning object wearing an MR coil by using the target attenuation map, and obtain the reconstructed PET image corresponding to the target scanning object wearing an MR coil by using the corrected PET data.

[0076] The aforementioned medical image processing method, apparatus, device, storage medium, and computer program product acquire an MR image corresponding to an MR coil and an attenuation map of a CT coil corresponding to the MR coil. The MR image is obtained by performing magnetic resonance scanning on a target object wearing an MR coil. The MR image and the CT coil attenuation map are registered to obtain a target attenuation map. The PET data corresponding to the target object wearing an MR coil is attenuated using the target attenuation map to obtain a reconstructed PET image.

[0077] Thus, in PET / MR scanning imaging, by performing magnetic resonance scanning on a target object wearing an MR coil to obtain the coil's MR image, the MR coil can be located in the field of view (FOV). Then, by registering the pre-acquired CT coil attenuation map corresponding to the MR coil with the coil's MR image, the actual deformation of the MR coil can be accurately captured during registration. Therefore, the registered target attenuation map matches the deformation field information of the MR coil. In PET / MR scanning imaging of a target object wearing an MR coil, the attenuation information of the MR coil can be accurately obtained based on the target attenuation map. This allows for accurate correction of attenuation and scattering caused by the MR coil during the attenuation correction of the PET data corresponding to the target object based on the target attenuation map, resulting in a highly accurate reconstructed PET image. This solves the problem of poor correction accuracy in PET / MR scanning imaging caused by the non-fixed position and shape of the MR coil during the scanning task, which necessitates the use of fixed attenuation maps or reliance on the correspondence between a very small number of points placed outside the coil for attenuation correction. Consequently, in PET / MR scanning imaging of a target object wearing an MR coil, the quantitative accuracy of PET is improved, resulting in a more accurate reconstructed PET image.

[0078] In one embodiment, registering the coil MR image and the CT coil attenuation map to obtain a target attenuation map includes: registering the coil MR image and the CT coil attenuation map to obtain a registered coil attenuation map; and obtaining the target attenuation map based on the object body attenuation map and the coil attenuation map corresponding to the target scan object.

[0079] Among them, the object body attenuation map is the attenuation map corresponding to the target scan object body.

[0080] In practice, during the process of registering the coil MR image and the CT coil attenuation map to obtain the target attenuation map, the computer equipment can register the coil MR image and the CT coil attenuation map to obtain the registered coil attenuation map; then, the computer equipment can obtain the object body attenuation map corresponding to the target scan object, and obtain the target attenuation map corresponding to the target scan object wearing the MR coil based on the registered coil attenuation map and the object body attenuation map.

[0081] In practical applications, computer equipment can register the CT coil attenuation map with the deformation field information of the coil MR image to obtain the registered coil attenuation map.

[0082] The technical solution of this embodiment obtains a registered coil attenuation map by registering the coil MR image and the CT coil attenuation map; and obtains a target attenuation map based on the object body attenuation map and the coil attenuation map corresponding to the target scan object. Thus, by registering the CT coil attenuation map corresponding to the MR coil with the coil MR image, the actual deformation of the MR coil can be accurately captured during registration. Therefore, the registered coil attenuation map matches the deformation field information of the MR coil. In PET / MR scanning imaging of a target scan object wearing an MR coil, the attenuation information of the MR coil can be accurately obtained based on the coil attenuation map. This allows for accurate correction of attenuation and scattering caused by the MR coil during PET data reconstruction. Furthermore, the target attenuation map obtained from the object body attenuation map and the coil attenuation map can automatically and accurately correct the attenuation of the PET data corresponding to the target scan object, resulting in a more accurate reconstructed PET image.

[0083] In one embodiment, the magnetic resonance sequence used in the magnetic resonance scan is a dual-echo magnetic resonance sequence. For example... Figure 2 As shown, step S110, acquiring the MR image of the MR coil, includes the following steps:

[0084] Step S210: Obtain the first MR image corresponding to the first echo signal of the dual-echo magnetic resonance sequence, and the second MR image corresponding to the second echo signal of the dual-echo magnetic resonance sequence.

[0085] Among them, the dual-echo magnetic resonance sequence can be a 3D dual-echo magnetic resonance sequence.

[0086] The echo time of the first echo signal is shorter than that of the second echo signal.

[0087] The first MR image includes an MR coil and the target object being scanned.

[0088] The second MR image includes the target scanned object.

[0089] In a specific implementation, during the magnetic resonance scanning of a target object wearing an MR coil in a PET / MR system, the magnetic resonance sequence of the magnetic resonance scan can be a dual-echo magnetic resonance sequence (e.g., a 3D dual-echo magnetic resonance sequence). In this way, the computer device can acquire the first MR image of the target object wearing an MR coil under the first echo signal of the dual-echo magnetic resonance sequence, and the second MR image under the second echo signal of the dual-echo magnetic resonance sequence.

[0090] The first MR image includes an MR coil and the target object being scanned; the second MR image includes the target object but does not include an MR coil.

[0091] The echo time of the first echo signal is shorter than that of the second echo signal. The first echo signal can acquire a short T2 signal, and some metals in the MR coil are short T2 signals. Therefore, the first echo signal can be used to directly image the MR coil, so that the first MR image corresponding to the first echo signal can contain the MR coil, so as to realize the imaging and positioning of the MR coil through the first MR image.

[0092] Among them, the short T2 signal is a weak signal value in magnetic resonance imaging that is mainly used to reflect the nature of tissue lesions.

[0093] Step S220: Based on the second MR image, identify the MR coil in the first MR image to obtain the coil MR image.

[0094] In practice, a computer device can identify the MR coil in a first MR image that contains both the MR coil and the target scanning object based on a second MR image that contains the target scanning object but not the MR coil, thus obtaining a coil MR image.

[0095] In this embodiment, the magnetic resonance sequence for magnetic resonance scanning is a dual-echo magnetic resonance sequence. A first MR image corresponding to the first echo signal of the dual-echo magnetic resonance sequence and a second MR image corresponding to the second echo signal of the dual-echo magnetic resonance sequence are acquired. The echo time of the first echo signal is shorter than the echo time of the second echo signal. The first MR image includes an MR coil and a target scanning object. The second MR image includes the target scanning object. Based on the second MR image, the MR coil is identified in the first MR image to obtain a coil MR image.

[0096] Thus, by employing a dual-echo magnetic resonance sequence to perform magnetic resonance scanning on a target object wearing an MR coil, the MR coil can be imaged under the first echo signal with a shorter echo time in the dual-echo magnetic resonance sequence, obtaining a first MR image corresponding to the first echo signal that includes the MR coil and the target object. Simultaneously, a second MR image corresponding to the second echo signal with a longer echo time in the dual-echo magnetic resonance sequence can also be obtained, and this second MR image includes the target object. Therefore, the MR coil can be accurately identified in the first MR image containing both the MR coil and the target object through the second MR image containing the target object, thereby obtaining the coil MR image.

[0097] In one embodiment, identifying an MR coil in a first MR image based on a second MR image to obtain a coil MR image includes: performing threshold binarization processing on the first MR image and the second MR image respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image; subtracting the first MR mask image and the second MR mask image to obtain a subtracted MR mask image; and using the subtracted MR mask image as the coil MR image.

[0098] In a specific implementation, during the process of identifying the MR coil in the first MR image based on the second MR image and obtaining the coil MR image, the computer device can perform thresholding processing on the first MR image and the second MR image respectively to obtain a first MR binarized image corresponding to the first MR image and a second MR binarized image corresponding to the second MR image; then, it performs morphological closure operation on the first MR binarized image and the second MR binarized image respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image.

[0099] Thus, since the MR coil only images under the first echo signal and not under the second echo signal, the first MR mask image containing the MR coil and the target scanning object can be subtracted from the second MR mask image containing the target scanning object but not the MR coil to remove the image of the target scanning object body, resulting in the subtracted MR mask image. This subtracted MR mask image does not contain the target scanning object but contains the MR coil, and can be used as the coil MR image corresponding to the MR coil.

[0100] The technical solution of this embodiment involves performing threshold binarization processing on the first MR image and the second MR image respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image; subtracting the first MR mask image and the second MR mask image to obtain the subtracted MR mask image; and using the subtracted MR mask image as the coil MR image.

[0101] Thus, by subtracting the first MR mask image containing the MR coil and the target scanning object under the first echo signal from the second MR mask image containing only the target scanning object under the second echo signal, the subtracted MR mask image after removing the image of the target scanning object body can be obtained as the coil MR image corresponding to the MR coil. Therefore, during the registration process between the coil MR image and the CT coil attenuation map, it will not be affected by the target scanning object, thus improving the registration accuracy.

[0102] In one embodiment, such as Figure 3As shown, the coil MR image and CT coil attenuation map are registered to obtain the registered coil attenuation map, including the following steps:

[0103] Step S310: Rigidly register the CT coil attenuation map and the coil MR image to obtain the CT coil attenuation map to be optimized.

[0104] In practical implementation, during the registration process between the CT coil MR image and the CT coil attenuation map to obtain the registered coil attenuation map, the computer equipment can first perform rigid registration between the CT coil attenuation map and the CT coil MR image to obtain the CT coil attenuation map to be optimized. Specifically, the computer equipment can rigidly register the CT coil attenuation map to the CT coil MR image to obtain the CT coil attenuation map to be optimized. In practical applications, the computer equipment can use a normalized mutual information maximization algorithm to rigidly register the CT coil attenuation map to the CT coil MR image to obtain the CT coil attenuation map to be optimized.

[0105] Step S320: Perform non-rigid registration on the CT coil attenuation map and the coil MR image to be optimized to obtain the coil attenuation map.

[0106] In practical implementation, after obtaining the CT coil attenuation map to be optimized, the computer device can perform non-rigid registration between the CT coil attenuation map and the coil MR image to obtain the registered coil attenuation map. Specifically, the computer device can non-rigidly register the CT coil attenuation map to be optimized to the coil MR image to obtain the registered coil attenuation map. In practical applications, the computer device can use the differential demos algorithm to non-rigidly register the CT coil attenuation map to be optimized to the coil MR image to obtain the registered coil attenuation map.

[0107] The technical solution of this embodiment obtains the CT coil attenuation map to be optimized by rigidly registering the CT coil attenuation map and the coil MR image; and obtains the coil attenuation map by non-rigid registration of the CT coil attenuation map to be optimized and the coil MR image. Thus, by first rigidly registering the CT coil attenuation map and the coil MR image and then performing non-rigid registration, the computational complexity in the non-rigid registration process can be reduced, and the registration efficiency can be improved. Simultaneously, by performing non-rigid registration of the CT coil attenuation map to be optimized with the coil MR image, the actual deformation of the MR coil can be captured. Therefore, the registered coil attenuation map matches the deformation field information of the MR coil, which can solve the problem of MR coil deformation in different scanning imaging tasks. This allows for accurate correction of attenuation and scattering caused by the MR coil during PET data reconstruction based on the registered coil attenuation map.

[0108] In one embodiment, the MR coil is a dual-sided MR coil; registering the coil MR image and the CT coil attenuation map to obtain a registered coil attenuation map includes: acquiring a first coil MR image and a second coil MR image corresponding to the coil MR image; the first coil MR image and the second coil MR image are images on both sides of the central axis of the MR coil in the coil MR image; registering the CT coil attenuation map and the first coil MR image to obtain a registered first CT coil attenuation map; registering the CT coil attenuation map and the second coil MR image to obtain a registered second CT coil attenuation map; and obtaining a coil attenuation map based on the registered first CT coil attenuation map and the registered second CT coil attenuation map.

[0109] The process of registering the CT coil attenuation map and the first coil MR image to obtain the registered first CT coil attenuation map includes: rigid registration of the CT coil attenuation map and the first coil MR image to obtain the first CT coil attenuation map to be optimized; and non-rigid registration of the first CT coil attenuation map to be optimized and the first coil MR image to obtain the registered first CT coil attenuation map.

[0110] The process of registering the CT coil attenuation map and the second coil MR image to obtain the registered second CT coil attenuation map includes: rigid registration of the CT coil attenuation map and the second coil MR image to obtain the second CT coil attenuation map to be optimized; and non-rigid registration of the second CT coil attenuation map to be optimized and the second coil MR image to obtain the registered second CT coil attenuation map.

[0111] Among them, the MR coil can be a dual-sided, multi-channel surface coil.

[0112] In specific implementation, the MR coil is a dual-sided MR coil. During the rigid registration of the CT coil attenuation map and the coil MR image to obtain the CT coil attenuation map to be optimized, the computer device can divide the coil MR image into two sides along the central axis of the MR coil, obtaining a first coil MR image and a second coil MR image. Then, the computer device can rigidly register the CT coil attenuation map with the first and second coil MR images respectively, obtaining the corresponding first and second CT coil attenuation maps to be optimized. Specifically, the computer device can rigidly register the CT coil attenuation map to the first coil MR image to obtain the first CT coil attenuation map to be optimized; and rigidly register the CT coil attenuation map to the second coil MR image to obtain the second CT coil attenuation map to be optimized. In practical applications, the computer device can use a normalized mutual information maximization algorithm for rigid registration.

[0113] In this way, the computer device can obtain the CT coil attenuation map to be optimized based on the first CT coil attenuation map to be optimized and the second CT coil attenuation map to be optimized.

[0114] In addition, non-rigid registration is performed on the CT coil attenuation map and the coil MR image to be optimized to obtain a coil attenuation map, including: non-rigid registration of the first CT coil attenuation map and the first coil MR image to be optimized to obtain a registered first CT coil attenuation map; non-rigid registration of the second CT coil attenuation map and the second coil MR image to be optimized to obtain a registered second CT coil attenuation map; and obtaining a coil attenuation map based on the registered first CT coil attenuation map and the registered second CT coil attenuation map.

[0115] The CT coil attenuation map to be optimized includes a first CT coil attenuation map to be optimized and a second CT coil attenuation map to be optimized.

[0116] In specific implementation, during the process of non-rigid registration of the CT coil attenuation map and the coil MR image to be optimized, the computer device can perform non-rigid registration on the first CT coil attenuation map and the first coil MR image to obtain a registered first CT coil attenuation map; and perform non-rigid registration on the second CT coil attenuation map and the second coil MR image to obtain a registered second CT coil attenuation map. Specifically, the computer device can non-rigidly register the first CT coil attenuation map to be optimized to the first coil MR image to obtain a registered first CT coil attenuation map; and non-rigidly register the second CT coil attenuation map to be optimized to the second coil MR image to obtain a registered second CT coil attenuation map. In practical applications, the computer device can use the differential demos algorithm for non-rigid registration.

[0117] Thus, the registered first CT coil attenuation map and the registered second CT coil attenuation map are the registered CT coil attenuation maps corresponding to both sides of the central axis of the MR coil in the coil MR image. By combining the registered first CT coil attenuation map and the registered second CT coil attenuation map, the complete registered coil attenuation map corresponding to the MR coil can be obtained.

[0118] In this embodiment, the MR coil is a dual-sided MR coil. The system acquires a first MR image and a second MR image corresponding to the MR image of the coil. The first and second MR images are images on both sides of the central axis of the MR coil in the MR image. The CT coil attenuation map and the first MR image are registered to obtain a registered first CT coil attenuation map. The CT coil attenuation map and the second MR image are then registered to obtain a registered second CT coil attenuation map. Based on the registered first and second CT coil attenuation maps, a coil attenuation map is obtained.

[0119] Thus, by performing the same registration method on the images on both sides of the central axis of the MR coil in the CT coil attenuation map and the coil MR image respectively, a first CT coil attenuation map and a second CT coil attenuation map corresponding to the images on both sides of the central axis of the MR coil are obtained. Based on the first CT coil attenuation map and the second CT coil attenuation map, a complete registered coil attenuation map corresponding to the MR coil can be obtained. Therefore, the complete registered coil attenuation map can be applied to the reconstruction of PET data for target scanning objects wearing MR coils to accurately correct the attenuation and scattering caused by the MR coil.

[0120] In one embodiment, such as Figure 4 As shown, step S130, obtaining the target attenuation map based on the object body attenuation map and coil attenuation map corresponding to the target scanning object, includes the following steps:

[0121] Step S410: Use the second MR image as the object body MR image corresponding to the target scan object.

[0122] In practice, during the process of obtaining the target attenuation map based on the object body attenuation map and the coil attenuation map corresponding to the target scan object, the computer device can use the second MR image that includes the target scan object but does not include the MR coil as the object body MR image corresponding to the target scan object.

[0123] Step S420: Determine the attenuation map of the object body based on the MR image of the object body.

[0124] In practice, computer equipment can determine the attenuation map of the target scanned object based on the MR image of the object itself.

[0125] Step S430: Add the attenuation map of the object body and the attenuation map of the coil to obtain the target attenuation map.

[0126] In practice, the computer device can add the attenuation map of the object body and the attenuation map of the registered coil to obtain the target attenuation map. This target attenuation map is matched with the PET data corresponding to the target scanning object wearing the MR coil, and can be used to perform attenuation correction on the PET data to obtain the reconstructed PET image.

[0127] The technical solution of this embodiment uses the second MR image as the object-body MR image corresponding to the target scanning object; determines the object-body attenuation map based on the object-body MR image; and adds the object-body attenuation map and the coil attenuation map to obtain the target attenuation map. Thus, in PET / MR scanning imaging of a target scanning object wearing an MR coil, by adding the object-body attenuation map corresponding to the target scanning object and the coil attenuation map corresponding to the MR coil, the target attenuation map in the PET / MR scanning imaging is obtained. Applying the target attenuation map to the PET data reconstruction of the target scanning object wearing an MR coil can not only correct the attenuation and scattering caused by the MR coil, but also correct the attenuation caused by the target scanning object itself, further improving the accuracy of the reconstructed PET image.

[0128] In another embodiment, such as Figure 5 As shown, a medical image processing method is provided. Taking the application of this method to the aforementioned computer device as an example, the method includes the following steps:

[0129] Step S510: Obtain the first MR image corresponding to the first echo signal of the dual-echo magnetic resonance sequence, and the second MR image corresponding to the second echo signal of the dual-echo magnetic resonance sequence.

[0130] Step S520: Threshold binarization processing is performed on the first MR image and the second MR image respectively to obtain the first MR mask image corresponding to the first MR image and the second MR mask image corresponding to the second MR image.

[0131] Step S530: Subtract the first MR mask image from the second MR mask image to obtain the subtracted MR mask image.

[0132] Step S540: The subtracted MR mask image is used as the coil MR image corresponding to the MR coil, and the second MR image is used as the object body MR image corresponding to the target scanning object.

[0133] The MR coil includes a rigid head coil and a flexible body coil. This type of MR coil is connected to the medical imaging system via highly flexible cables, making it difficult to repeatedly place the coil in the same position within the field of view.

[0134] Step S550: Determine the attenuation map of the object body based on the MR image of the object body.

[0135] Step S560: Obtain the CT coil attenuation map corresponding to the MR coil, and perform rigid registration between the CT coil attenuation map and the coil MR image to obtain the CT coil attenuation map to be optimized.

[0136] The CT image corresponding to the MR coil is the image obtained after scanning the MR coil by the CT module in the PET / CT system or by a standalone CT system.

[0137] Among them, the CT coil attenuation map is an attenuation map obtained by computer equipment based on the CT image corresponding to the MR coil, which is transformed into an attenuation coefficient of 511keV by applying bilinear transformation.

[0138] Before applying a bilinear transform to convert the attenuation value represented by the CT image into an attenuation coefficient of 511 keV, the CT image is smoothed using a Gaussian smoothing filter.

[0139] Step S570: Perform non-rigid registration on the CT coil attenuation map and the coil MR image to be optimized to obtain the registered coil attenuation map.

[0140] Furthermore, to determine the accuracy of the registered coil attenuation map, four visible markers with a diameter of 8 mm can be placed on the outer surface of the MR coil in both the coil MR image and the CT coil attenuation map. After registration, the markers are positioned in both the coil MR image and the registered coil attenuation map, and the mean square distance between the markers is measured as an indicator of the accuracy of the registered coil attenuation map.

[0141] In addition, the percentage difference between the CT coil attenuation map and the registered coil attenuation map can be used to assess whether the registration process preserved the shape and attenuation coefficient of the CT coil attenuation map.

[0142] In addition, the registered coil attenuation map can be visually inspected to assess the shape of any deformed coil attenuation map.

[0143] Step S580: Add the attenuation map of the object body and the attenuation map of the coil to obtain the target attenuation map.

[0144] The target attenuation map is a spatially interpolated attenuation map, and its image size matches the image size corresponding to the PET data.

[0145] Step S590: Attenuation correction is performed on the PET data corresponding to the target scanning object wearing the MR coil using the target attenuation map to obtain the reconstructed PET image.

[0146] In the process of attenuation correction of PET data corresponding to the target scanning object wearing an MR coil by using the target attenuation map, and obtaining the reconstructed PET image corresponding to the target scanning object wearing an MR coil by using the corrected PET data, in addition to attenuation correction of PET data, dead time correction, scattering correction, random correction and normalization correction can also be performed on PET data to obtain corrected PET data. The corrected PET data is then reconstructed using the ordinary Poisson ordered subset expectation-maximization algorithm (OSEM) to obtain the reconstructed PET image.

[0147] The PET data and coil MR image are obtained by the PET / MR system simultaneously scanning the target object wearing the MR coil. During the synchronous scanning process, the computer can acquire the current PET data and the current MR data obtained by the PET module and MR module of the PET / MR system in real time. Then, the current PET data and the current MR data are compared and the comparison result corresponding to the current moment is obtained. If the comparison result corresponding to the current moment is a match and the comparison result corresponding to the previous moment is a mismatch, the MR module is controlled to stop executing the scan sequence to be executed at the current moment and trigger a new scan sequence to be executed to obtain normal MR data. Then, the normal MR data is reconstructed by triggering the reconstruction task corresponding to the MR module to obtain the coil MR image corresponding to the MR coil.

[0148] The computer equipment can control the MR module to execute or stop scanning of the scan sequence to be executed based on the current PET data.

[0149] The MR module can execute or stop the reconstruction of a task based on control commands from the computer device.

[0150] In this process, after the computer device acquires the current PET data collected by the PET module and the corresponding scan sequence to be executed by the MR module, the computer device can analyze and process the current PET data to obtain control instructions for the MR module. After receiving the control instructions, the MR module can execute or stop scanning the scan sequence to be executed according to the instructions.

[0151] It should be noted that the specific limitations of the above steps can be found in the specific limitations of a medical image processing method described above.

[0152] In another embodiment, such as Figure 6The diagram shows a flowchart of an attenuation correction method for a target scanning object wearing an MR coil. In practical applications, the MR coil can be a monkey coil, and the target scanning object can be a monkey. The following explanation uses the monkey coil as the MR coil and the monkey as the target scanning object. Figure 6 As shown, the MR module in the PET / MR system employs a dual-echo magnetic resonance sequence. After performing an MR scan on a monkey wearing a monkey coil, the computer can acquire a first MR image of the monkey wearing the monkey coil under the first echo signal of the dual-echo magnetic resonance sequence, and a second MR image under the second echo signal of the dual-echo magnetic resonance sequence. The computer can perform threshold binarization processing on the first and second MR images respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image. Then, the computer can subtract the first and second MR mask images to obtain a subtracted MR mask image after removing the image of the monkey body. This subtracted MR mask image is used as the coil MR image corresponding to the monkey coil. Simultaneously, the computer can determine the attenuation map of the monkey body based on the second MR image.

[0153] In addition, the PET module in the PET / MR system can scan a target object wearing an MR coil, and the computer equipment can obtain the PET data corresponding to the target object wearing the MR coil.

[0154] In addition, after the CT module in the PET / CT system or a standalone CT system scans the MR coil, the computer equipment can acquire the CT image corresponding to the monkey coil, and obtain the CT coil attenuation map corresponding to the monkey coil based on the CT image corresponding to the monkey coil.

[0155] Simultaneously, the computer device can acquire the first coil MR image and the second coil MR image on both sides of the central axis of the monkey coil in the coil MR image; then, the computer device can register the CT coil attenuation map and the first coil MR image, as well as register the CT coil attenuation map and the second coil MR image, to obtain the registered coil attenuation map corresponding to the monkey coil.

[0156] In this way, the computer device can obtain the target attenuation map corresponding to the monkey wearing the monkey coil based on the object attenuation map corresponding to the monkey and the coil attenuation map corresponding to the monkey coil. The PET data corresponding to the target scanning object wearing the MR coil is attenuated by the target attenuation map to obtain the reconstructed PET image.

[0157] It should be noted that the specific limitations of the steps in the above method can be found in the specific limitations of a medical image processing method described above, and will not be repeated here.

[0158] It should be understood that although the steps in the flowcharts of the above embodiments are shown sequentially according to the arrows, these steps are not necessarily executed in the order indicated by the arrows. Unless explicitly stated herein, there is no strict order restriction on the execution of these steps, and they can be executed in other orders. Moreover, at least some steps in the flowcharts of the above embodiments may include multiple steps or multiple stages. These steps or stages are not necessarily completed at the same time, but can be executed at different times. The execution order of these steps or stages is not necessarily sequential, but can be performed alternately or in turn with other steps or at least some of the steps or stages of other steps.

[0159] Based on the same inventive concept, this application also provides a medical image processing apparatus for implementing the aforementioned medical image processing method. The solution provided by this apparatus is similar to the implementation described in the above method; therefore, the specific limitations in the one or more medical image processing apparatus embodiments provided below can be found in the above-described limitations of the medical image processing method, and will not be repeated here.

[0160] In one embodiment, such as Figure 7 As shown, a medical image processing device is provided, including: an acquisition module 710, a registration module 720, and a correction module 730, wherein:

[0161] The acquisition module 710 is used to acquire the coil MR image corresponding to the MR coil and the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on a target object wearing the MR coil.

[0162] The registration module 720 is used to register the coil MR image and the CT coil attenuation map to obtain the target attenuation map.

[0163] The correction module 730 is used to perform attenuation correction on the PET data corresponding to the target scanning object wearing the MR coil through the target attenuation map to obtain the reconstructed PET image.

[0164] In one embodiment, the registration module 720 is specifically used to register the coil MR image and the CT coil attenuation map to obtain a registered coil attenuation map; and to obtain the target attenuation map based on the object body attenuation map corresponding to the target scan object and the coil attenuation map.

[0165] In one embodiment, the magnetic resonance sequence of the magnetic resonance scan is a dual-echo magnetic resonance sequence. The acquisition module 710 is specifically used to acquire a first MR image corresponding to the first echo signal of the dual-echo magnetic resonance sequence and a second MR image corresponding to the second echo signal of the dual-echo magnetic resonance sequence; the echo time of the first echo signal is shorter than the echo time of the second echo signal; the first MR image includes the MR coil and the target scanning object; the second MR image includes the target scanning object; based on the second MR image, the MR coil is identified in the first MR image to obtain the coil MR image.

[0166] In one embodiment, the acquisition module 710 is specifically used to perform binarization processing on the first MR image and the second MR image respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image; subtract the first MR mask image and the second MR mask image to obtain a subtracted MR mask image; and use the subtracted MR mask image as the coil MR image.

[0167] In one embodiment, the registration module 720 is specifically used to use the second MR image as the object body MR image corresponding to the target scanning object; determine the object body attenuation map based on the object body MR image; and add the object body attenuation map and the coil attenuation map to obtain the target attenuation map.

[0168] In one embodiment, the registration module 720 is specifically used to perform rigid registration of the CT coil attenuation map and the coil MR image to obtain a CT coil attenuation map to be optimized; and to perform non-rigid registration of the CT coil attenuation map to be optimized and the coil MR image to obtain the coil attenuation map.

[0169] In one embodiment, the MR coil is a dual-sided MR coil; the registration module 720 is specifically used to acquire a first MR image and a second MR image corresponding to the MR image of the coil; the first MR image and the second MR image are images on both sides of the central axis of the MR coil in the MR image of the coil; the CT coil attenuation map and the first MR image are registered to obtain a registered first CT coil attenuation map; the CT coil attenuation map and the second MR image are registered to obtain a registered second CT coil attenuation map; the coil attenuation map is obtained based on the registered first CT coil attenuation map and the registered second CT coil attenuation map.

[0170] The various modules in the aforementioned medical image processing device can be implemented entirely or partially through software, hardware, or a combination thereof. These modules can be embedded in or independent of the processor in a computer device in hardware form, or stored in the memory of a computer device in software form, so that the processor can call and execute the operations corresponding to each module.

[0171] In one embodiment, a computer device is provided, which may be a terminal, and its internal structure diagram may be as follows: Figure 8 As shown, the computer device includes a processor, memory, input / output interface, communication interface, display unit, and input device. The processor, memory, and input / output interface are connected via a system bus, and the communication interface, display unit, and input device are also connected to the system bus via the input / output interface. The processor provides computational and control capabilities. The memory includes non-volatile storage media and internal memory. The non-volatile storage media stores the operating system and computer programs. The internal memory provides an environment for the operation of the operating system and computer programs stored in the non-volatile storage media. The input / output interface is used for exchanging information between the processor and external devices. The communication interface is used for wired or wireless communication with external terminals; wireless communication can be achieved through Wi-Fi, mobile cellular networks, NFC (Near Field Communication), or other technologies. When the computer program is executed by the processor, it implements a medical image processing method. The display unit is used to form a visually visible image and can be a display screen, projection device, or virtual reality imaging device. The display screen can be an LCD screen or an e-ink screen. The input device of the computer device can be a touch layer covering the display screen, or buttons, trackballs, or touchpads set on the casing of the computer device, or external keyboards, touchpads, or mice, etc.

[0172] Those skilled in the art will understand that Figure 8 The structure shown is merely a block diagram of a portion of the structure related to the present application and does not constitute a limitation on the computer device to which the present application is applied. Specific computer devices may include more or fewer components than those shown in the figure, or combine certain components, or have different component arrangements.

[0173] In one embodiment, a computer device is also provided, including a memory and a processor, wherein the memory stores a computer program, and the processor executes the computer program to implement the steps in the above method embodiments.

[0174] In one embodiment, a computer-readable storage medium is provided having a computer program stored thereon that, when executed by a processor, implements the steps in the above method embodiments.

[0175] In one embodiment, a computer program product is provided, including a computer program that, when executed by a processor, implements the steps in the above method embodiments.

[0176] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, data stored, data displayed, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use and processing of the relevant data shall comply with the relevant laws, regulations and standards of the relevant countries and regions.

[0177] Those skilled in the art will understand that all or part of the processes in the methods of the above embodiments can be implemented by a computer program instructing related hardware. The computer program can be stored in a non-volatile computer-readable storage medium, and when executed, it can include the processes of the embodiments of the above methods. Any references to memory, databases, or other media used in the embodiments provided in this application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM can take many forms, such as Static Random Access Memory (SRAM) or Dynamic Random Access Memory (DRAM). The databases involved in the embodiments provided in this application may include at least one type of relational database and non-relational database. Non-relational databases may include, but are not limited to, blockchain-based distributed databases. The processors involved in the embodiments provided in this application may be general-purpose processors, central processing units, graphics processing units, digital signal processors, programmable logic devices, quantum computing-based data processing logic devices, etc., and are not limited to these.

[0178] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0179] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are specific and detailed, they should not be construed as limiting the scope of this patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this application should be determined by the appended claims.

Claims

1. A medical image processing method, characterized in that, The method includes: The MR coil image corresponding to the MR coil is obtained, as well as the CT coil attenuation map corresponding to the MR coil; the MR coil image is obtained by performing magnetic resonance scanning on a target object wearing the MR coil; the CT coil attenuation map is obtained by converting the CT image corresponding to the MR coil into a PET image. The MR image of the coil and the attenuation map of the CT coil are registered to obtain the target attenuation map; The PET data corresponding to the target scanning object wearing the MR coil is attenuated by the target attenuation map to obtain the reconstructed PET image.

2. The method according to claim 1, characterized in that, The registration of the coil MR image and the CT coil attenuation map to obtain the target attenuation map includes: The coil MR image and the CT coil attenuation map are registered to obtain the registered coil attenuation map. The target attenuation map is obtained based on the object body attenuation map corresponding to the target scanning object and the coil attenuation map.

3. The method according to claim 2, characterized in that, The magnetic resonance sequence for the magnetic resonance scan is a dual-echo magnetic resonance sequence; acquiring the coil MR image corresponding to the MR coil includes: A first MR image corresponding to the first echo signal of the dual-echo magnetic resonance sequence and a second MR image corresponding to the second echo signal of the dual-echo magnetic resonance sequence are acquired; the echo time of the first echo signal is shorter than the echo time of the second echo signal; the first MR image includes the MR coil and the target scanning object; the second MR image includes the target scanning object. Based on the second MR image, the MR coil is identified in the first MR image to obtain the MR image of the coil.

4. The method according to claim 3, characterized in that, The step of identifying the MR coil in the first MR image based on the second MR image to obtain the MR image of the coil includes: The first MR image and the second MR image are binarized respectively to obtain a first MR mask image corresponding to the first MR image and a second MR mask image corresponding to the second MR image. Subtract the first MR mask image from the second MR mask image to obtain the subtracted MR mask image; The subtracted MR mask image is used as the coil MR image.

5. The method according to claim 3, characterized in that, The step of obtaining the target attenuation map based on the object body attenuation map corresponding to the target scanning object and the coil attenuation map includes: The second MR image is used as the object body MR image corresponding to the target scan object; Based on the MR image of the object body, determine the attenuation map of the object body; The target attenuation map is obtained by adding the attenuation map of the object body and the attenuation map of the coil.

6. The method according to claim 2, characterized in that, The MR coil is a dual-sided MR coil; the registration of the MR image of the coil and the attenuation map of the CT coil to obtain the registered coil attenuation map includes: Obtain the first coil MR image and the second coil MR image corresponding to the coil MR image; the first coil MR image and the second coil MR image are images on both sides of the central axis of the MR coil in the coil MR image; The CT coil attenuation map and the first coil MR image are registered to obtain the registered first CT coil attenuation map. The CT coil attenuation map and the second coil MR image are registered to obtain the registered second CT coil attenuation map. The coil attenuation map is obtained based on the registered first CT coil attenuation map and the registered second CT coil attenuation map.

7. The method according to claim 2, characterized in that, The process of registering the coil MR image and the CT coil attenuation map to obtain the registered coil attenuation map includes: Rigid registration is performed on the CT coil attenuation map and the coil MR image to obtain the CT coil attenuation map to be optimized; The coil attenuation map is obtained by non-rigid registration of the CT coil attenuation map to be optimized and the coil MR image.

8. A medical image processing device, characterized in that, The device includes: The acquisition module is used to acquire the coil MR image corresponding to the MR coil, and to acquire the CT coil attenuation map corresponding to the MR coil; the coil MR image is obtained by performing magnetic resonance scanning on a target object wearing the MR coil; the CT coil attenuation map is the attenuation map obtained by converting the CT image corresponding to the MR coil into a PET image. The registration module is used to register the coil MR image and the CT coil attenuation map to obtain the target attenuation map; The correction module is used to perform attenuation correction on the PET data corresponding to the target scanning object wearing the MR coil using the target attenuation map, so as to obtain the reconstructed PET image.

9. A computer device comprising a memory and a processor, wherein the memory stores a computer program, characterized in that, When the processor executes the computer program, it implements the steps of the method according to any one of claims 1 to 7.

10. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the computer program is executed by a processor, it implements the steps of the method according to any one of claims 1 to 7.

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