Apparatus for controlling a raman spectrometer
By controlling the Raman spectrometer and utilizing image analysis and automatic/manual control, the problems of long detection time, high cost, and insufficient accuracy of existing microbial detection technologies have been solved, achieving efficient and low-cost microbial detection.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- POINT ROBOTICS MEDTECH INC
- Filing Date
- 2022-10-11
- Publication Date
- 2026-05-26
AI Technical Summary
Existing microbial detection technologies, such as biochemical detection and MALDI-TOF mass spectrometry, suffer from problems such as long detection time, high cost, and insufficient accuracy. Although Raman spectrometers are low-cost and have simple environmental requirements, human-computer interaction needs to be improved to enhance detection efficiency and accuracy.
A device for controlling a Raman spectrometer is provided, comprising an image acquisition and analysis unit, a processing unit, a human-machine interface unit, and a material control unit. The device determines the priority level of blocks through image analysis and performs automatic or manual control, and optimizes the detection process by combining laser measurement and cleaning control.
It improves the control accuracy and detection efficiency of Raman spectrometers, reduces measurement time, optimizes detection results, enhances human-computer interaction, and reduces equipment maintenance costs.
Smart Images

Figure CN116008246B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to a control device, and more particularly to a device for controlling a Raman spectrometer. Background Technology
[0002] Current major microbial detection technologies include biochemical detection, matrix-assisted laser desorption / ionization time-of-flight (MALDI-TOF) mass spectrometry, and Raman spectroscopy. Biochemical detection requires long-term microbial culture, and different microorganisms may require specific biological reaction methods for identification, making direct, rapid, and accurate microbial detection impossible. MALDI-TOF mass spectrometry uses the mass / charge ratio spectra of proteins from different protein samples of the analyte microorganisms generated in a vacuum flight tube for microbial identification. Although faster than biochemical detection, different microorganisms may have similar protein spectra, affecting the accuracy of identification. In addition, MALDI-TOF mass spectrometers are expensive, have stringent operating environment requirements, and incur high costs for consumables and maintenance, limiting their widespread use in microbial detection.
[0003] Compared to MALDI-TOF mass spectrometry, Raman spectroscopy offers advantages such as lower equipment cost and simpler environmental requirements, and is suitable for detecting a wide range of microorganisms (e.g., bacteria, fungi, viruses). Furthermore, with the increasingly powerful image recognition capabilities of artificial intelligence, combining it with Raman spectroscopy results can accurately and rapidly identify microbial species, providing guidance for subsequent clinical diagnosis and treatment. Summary of the Invention
[0004] The present invention provides a device for controlling a Raman spectrometer, thereby enhancing the control of the Raman spectrometer.
[0005] To address the aforementioned technical problems, one technical solution adopted by this invention is to provide a device for controlling a Raman spectrometer, comprising an image acquisition and analysis unit, a processing unit, a human-machine interface unit, and a material carrier control unit. The image acquisition and analysis unit acquires image information of a test object and divides the image information into multiple blocks, each block having corresponding block information. The processing unit is electrically connected to the image acquisition and analysis unit. The processing unit compares the block information with a predetermined image information value range or threshold value to determine whether the corresponding block has a first priority analysis level. The human-machine interface unit is electrically connected to the image acquisition and analysis unit and the processing unit. The human-machine interface unit receives user input for each block with a first priority analysis level to record whether each block has a second priority analysis level. The material carrier control unit is electrically connected to the human-machine interface unit. The material carrier control unit controls the position of the test object for blocks with a second priority analysis level and enables Raman spectroscopy detection in those blocks.
[0006] Preferably, when the processing unit compares the block information with a predetermined image information value range or threshold value to determine whether the corresponding block has a first priority analysis level, if the block information falls within the predetermined image information value range, the processing unit determines that the corresponding block has a first priority analysis level; if the block information does not fall within the predetermined image information value range, the processing unit determines that the corresponding block does not have a first priority analysis level.
[0007] Preferably, the human-machine interface unit includes a first mode module and a second mode module. The first mode module includes a first mode, in which the first mode module provides a first instruction to the user for each block with a first priority analysis level, and automatically records whether each block has a second priority analysis level in response to user input corresponding to the first instruction. The second mode module includes a second mode, in which the second mode module provides a second instruction to the user for each block determined by the user to have a first priority analysis level, and determines whether to record whether the user-determined blocks have a second priority analysis level in response to user input corresponding to the second instruction.
[0008] Preferably, the device for controlling the Raman spectrometer further includes a laser measurement control unit electrically connected to the human-machine interface unit and the object control unit.
[0009] Preferably, the human-machine interface unit includes a third mode module and a fourth mode module. The third mode module includes a third mode in which the third mode module provides a third instruction to the user for each block with a first priority analysis level. The third mode module automatically records whether each block has a second priority analysis level in response to the user input corresponding to the third instruction and transmits the information of blocks with the second priority analysis level to the laser measurement control unit. The laser measurement control unit analyzes and determines whether the information of blocks with the second priority analysis level has a third priority analysis level and transmits the information of blocks with the third priority analysis level to the third mode module. The third mode module automatically records whether each block has a third priority analysis level. The fourth mode module includes a fourth mode. In the fourth mode, the fourth mode module transmits the block information with the second priority analysis level determined by each user to the laser measurement and control unit. The laser measurement and control unit analyzes and determines whether the block information with the second priority analysis level has a third priority analysis level and transmits it to the fourth mode module. The fourth mode module provides a fourth indication to the user regarding whether each block has a third priority analysis level. The fourth mode module records whether each block has a third priority analysis level in accordance with the user input corresponding to the fourth indication.
[0010] Preferably, the device for controlling the Raman spectrometer further includes a cleaning control unit electrically connected to a human-machine interface unit.
[0011] Preferably, the cleaning control unit performs an automatic control to clean the detection space within the Raman spectrometer.
[0012] Preferably, the human-machine interface unit includes a fifth mode module. The fifth mode module includes a fifth mode in which the fifth mode module provides a fifth indication to the user regarding the number of times the substrate carrying the analyte is used, the number of times the stage of the Raman spectrometer enters and exits the detection space of the Raman spectrometer, or the duration of continuous operation of the Raman spectrometer. The fifth mode module determines whether to clean the detection space of the Raman spectrometer based on the user input corresponding to the fifth indication.
[0013] One of the beneficial effects of the present invention is that the device for controlling a Raman spectrometer provided by the present invention can enhance the human-computer interaction between the user and the Raman spectrometer, improve the control of the Raman spectrometer, reduce measurement time and optimize detection results by using the technical solution of "system automatic comparison to determine whether the corresponding block has a first priority analysis level and user input confirmation of whether each block has a second priority analysis level".
[0014] To further understand the features and technical content of the present invention, please refer to the following detailed description and drawings of the present invention. However, the drawings provided are for reference and illustration only and are not intended to limit the present invention. Attached Figure Description
[0015] Figure 1 This is a functional block diagram of a device for controlling a Raman spectrometer according to a first embodiment of the present invention.
[0016] Figure 2 This is a schematic diagram of the user interface of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.
[0017] Figure 3 This is a flowchart of the first fully automatic mode of the first fully automatic mode module of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.
[0018] Figure 4 This is a first mode flowchart of the first mode module of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.
[0019] Figure 5 This is a second mode flowchart of the second mode module of the device for controlling a Raman spectrometer according to the first embodiment of the present invention.
[0020] Figure 6 This is a functional block diagram of a device for controlling a Raman spectrometer according to a second embodiment of the present invention.
[0021] Figure 7 This is a flowchart of the second fully automatic mode of the second fully automatic mode module of the device for controlling a Raman spectrometer according to the second embodiment of the present invention.
[0022] Figure 8 This is a third-mode flowchart of the third-mode module of the device for controlling a Raman spectrometer according to the second embodiment of the present invention.
[0023] Figure 9 This is a flowchart of the fourth mode of the device for controlling a Raman spectrometer according to the second embodiment of the present invention.
[0024] Figure 10 This is a functional block diagram of a device for controlling a Raman spectrometer according to a third embodiment of the present invention.
[0025] Figure 11 This is a fifth mode flowchart of the fifth mode module of the device for controlling a Raman spectrometer according to the third embodiment of the present invention. Detailed Implementation
[0026] The following specific embodiments illustrate the implementation of the present invention. Those skilled in the art can understand the advantages and effects of the present invention from the content provided in this specification. The present invention can be implemented or applied through other different specific embodiments, and various details in this specification can also be modified and changed based on different viewpoints and applications without departing from the concept of the present invention. Furthermore, the accompanying drawings of the present invention are for simple illustrative purposes only and are not depictions of actual dimensions; this is stated in advance. The following embodiments will further describe the relevant technical content of the present invention in detail, but the content provided is not intended to limit the scope of protection of the present invention.
[0027] [First Embodiment]
[0028] See Figure 1 As shown, the first embodiment of the present invention provides a device D for controlling a Raman spectrometer. The device D for controlling a Raman spectrometer can be set inside or connected to a Raman spectrometer. It includes: an image acquisition and analysis unit 1, a processing unit 2, a human-machine interface unit 3, and a material control unit 4.
[0029] Image capturing and analysis unit 1 is used to capture an image of a test object M to obtain image information (IMG) of the test object M. Image capturing and analysis unit 1 may include an optical sensing element, such as, but not limited to, a charge-coupled device (CCD) or a complementary metal-oxide-semiconductor (CMOS) image sensor. In one embodiment, image capturing and analysis unit 1 is connected to an optical lens. The optical lens captures an image of the test object M, and image capturing and analysis unit 1 analyzes the image of the test object M to obtain an image information (IMG). The image information (IMG) is divided into multiple blocks, and each block has its corresponding block information. For example, the image information (IMG) may be the optical features of the test object M, such as its shape, brightness, and color, but this invention is not limited thereto. Furthermore, the block information may be the optical features of the block, such as brightness, color, grayscale value, color block density, and color block area, but this invention is not limited thereto.
[0030] Processing unit 2 is electrically connected to image capturing and analysis unit 1. Processing unit 2 can compare multiple blocks of image information (IMG) with a predetermined image information value range to determine the first priority analysis level of each block. For example, the predetermined image information value range can be a predetermined brightness value range, where the image grayscale value is between 120 and 250. When the block information value of one of the multiple blocks falls within the predetermined brightness value range, i.e., the block image grayscale value is between 120 and 250, processing unit 2 records one of the multiple blocks as having the first priority analysis level. When the block information value of another block does not fall within the predetermined brightness value range, i.e., the block image grayscale value is less than 120 or greater than 250, processing unit 2 records the other block as not having the first priority analysis level. It should be noted that although a value range is used as the basis for comparison in this embodiment, a threshold value can also be used as the basis for comparison in other embodiments, and the present invention is not limited thereto.
[0031] Furthermore, the device D for controlling the Raman spectrometer may also include a database (not shown in the figure), which may be electrically or communicatively connected to the processing unit 2 and the human-machine interface unit 3. The database may store image information or Raman spectral patterns of different types of biological or non-biological organisms, which can be used to compare and analyze with the analyte M to predict or determine the classification of the analyte M.
[0032] The human-machine interface unit 3 is electrically connected to the image acquisition and analysis unit 1 and the processing unit 2. For example... Figure 2 As shown, the human-machine interface unit 3 may include a user interface. The user interface can be used to store and display user interface configuration data regarding image information (IMG) or block information. The user interface may be a device with a liquid crystal display (LCD) or an organic light-emitting diode (OLED) display, etc., but this invention is not limited thereto. For example, such as... Figure 2As shown, the user interface can be configured with a display module 31, which can display a real-time image or a non-real-time image of the object under test M on the screen for user reference. Furthermore, the human-machine interface unit 3 can receive user input via a keyboard, mouse, touchpad, or touchscreen input device; this invention is not limited thereto. The user interface can also be configured with a human-machine interface control module 32, through which different stages of the detection process of the object under test M can be controlled. For example, different stages of the detection process may include a detection start function, a detection end function, and a control function for the display module 31 to display the image of the object under test M, etc. The configuration of the human-machine interface control module 32 can be adjusted according to user needs; this invention is not limited thereto. In addition, the human-machine interface control module 32 can also be configured with a user manual control unit to facilitate the control of functions such as moving the stage carrying the test object M (including moving the stage into / out of the Raman spectrometer, etc.), controlling laser parameters (including laser energy, time, number of transmit / receive cycles, etc.), controlling the laser detector temperature, and controlling measurement modes (including fast, accurate, and high-precision modes, etc.) during the detection process. The configuration of the user manual control unit can be adjusted according to user needs, and this invention is not limited thereto.
[0033] In addition, the user interface can be configured with a analyte configuration module 33 to display a configuration mode of the analyte M and provide a rapid positioning function for the analyte M. The user interface can also be configured with a Raman spectroscopy graphics module 34, which can display a real-time or non-real-time Raman spectroscopy image of the analyte M. The user interface can also be configured with a Raman spectroscopy prediction result display module 35, which can display the Raman spectroscopy prediction results of the analyte M to help the user determine whether to perform subsequent Raman spectroscopy analysis.
[0034] Furthermore, the human-machine interface unit 3 may include a first fully automatic mode module, which includes a first fully automatic mode. More specifically, as... Figure 3As shown, in the first fully automatic mode, the first fully automatic mode module of the human-machine interface unit 3 automatically determines and records whether each block has a first priority analysis level based on the analysis results of the processing unit 2. Then, it automatically records the sampling area with a second priority analysis level and transmits a first fully automatic control signal ACS1 to the material control unit 4 to control the displacement of the sampling area. Raman spectroscopy analysis is then performed based on the image information (IMG) or block information of the sampling area. In other words, in the first fully automatic mode, the human-machine interface unit 3 can automatically complete all Raman spectroscopy detection processes. It should be noted that the determination of the first priority analysis level here is, for example, based on the analysis of the image information (IMG) or block information to identify whether there is a sufficient number of samples in the block; while the determination of the second priority analysis level is, for example, based on the analysis of the image information (IMG) or block information to identify the sample density in the block. However, the present invention is not limited to this, and the criteria for determining whether there is a first or second priority analysis level can be changed according to the user's needs.
[0035] Furthermore, the human-machine interface unit 3 may also include a first mode module and a second mode module. The first mode module includes a first mode, which is a semi-automatic measurement mode. The second mode module includes a second mode, which is a user-manual measurement mode.
[0036] like Figure 4 As shown, in the first mode, the first mode module of the human-machine interface unit 3 automatically determines and records whether each block has a first priority analysis level based on the analysis results of the processing unit 2, and provides a first instruction to the user. Then, in response to a user input corresponding to the first instruction, the first mode module of the human-machine interface unit 3 automatically records the sampling area with a second priority analysis level, and transmits a first control signal CS1 to the material control unit 4 to control the displacement of the sampling area through the material control unit 4, and performs Raman spectroscopy analysis based on the image information (IMG) or block information of the sampling area.
[0037] like Figure 5As shown, in the second mode, the human-machine interface unit 3 determines the sampling area based on user input. In one embodiment, after receiving user input (corresponding to the user's desired selection of a sampling area), the second mode module of the human-machine interface unit 3 provides a second instruction to the user based on whether the image information (IMG) or block information of the sampling area has a first priority analysis level. Then, in response to a user instruction corresponding to the second instruction, the second mode module of the human-machine interface unit 3 determines whether to record that the sampling area has a second priority analysis level, and transmits a second control signal CS2 to the object control unit 4 based on whether the sampling area has a second priority analysis level. This allows the object control unit 4 to control the position of the analyte M, causing the sampling area with the second priority analysis level to shift, and Raman spectroscopy analysis to be performed based on the image information (IMG) or block information of the sampling area. In one embodiment, the second instruction provided by the second mode module of the human-machine interface unit 3 is based on whether the image information (IMG) or block information of the area has a first priority analysis level; therefore, the content of the second instruction can be "It is recommended that the user determine and record that the sampling area has a second priority analysis level." In another embodiment, the second instruction provided by the second mode module of the human-machine interface unit 3 is "based on the image information IMG or block information of the area range, it does not have a first priority analysis level." Therefore, the content of the second instruction can be "It is recommended that the user not record that the sampling area has a second priority analysis level." However, the user may also choose not to follow the content of the second instruction and determine whether to input the corresponding user instruction as needed. The user can also reselect the sampling area and execute the second mode operation again. Furthermore, the second instruction can be adjusted according to actual needs, and the present invention is not limited thereto.
[0038] The sample carrier control unit 4 is electrically connected to the human-machine interface unit 3. In a first mode, the first mode module of the human-machine interface unit 3 automatically records the sampling area with a second priority analysis level according to the user input corresponding to the first instruction, and transmits a first control signal CS1 to the sample carrier control unit 4. Alternatively, in a second mode, the second mode module of the human-machine interface unit 3 records the sampling area with a second priority analysis level according to the user input corresponding to the second instruction, and transmits a second control signal CS2 to the sample carrier control unit 4. Thus, the sample carrier control unit 4 controls the movement of the analyte M so that the sampling area with the second priority analysis level can be subjected to Raman spectroscopy detection. The sample carrier control unit 4 is connected to a stage disposed within the Raman spectrometer, and the stage is driven by a stepper motor or a servo motor. In a preferred embodiment, the sample carrier control unit 4 is connected to a servo motor-driven stage. Furthermore, the stage connected to the sample carrier control unit 4 can be a single-axis stage or a multi-axis stage. In a preferred embodiment, the stage connected to the sample carrier control unit 4 is a multi-axis stage. In a more preferred embodiment, the stage connected to the sample carrier control unit 4 is a three-axis stage. Furthermore, the size and shape of the stage can be adjusted according to actual needs, and the area and shape of the region on the stage that bears the object to be tested M can also be adjusted according to actual needs; this invention does not impose any limitations.
[0039] However, the examples given above are merely one possible embodiment and are not intended to limit the invention.
[0040] [Second Embodiment]
[0041] The difference between the second embodiment and the first embodiment lies in the laser measurement and control unit. That is, the device for controlling the Raman spectrometer of the present invention can have a laser measurement and control unit. Furthermore, it should be noted that the other structures of the device D for controlling the Raman spectrometer provided in the second embodiment are similar to those in the first embodiment, and will not be described again here.
[0042] See Figure 6 As shown, in this embodiment, the device D for controlling a Raman spectrometer provided by the present invention may further include a laser measurement control unit 5. The laser measurement control unit 5 is electrically connected to the human-machine interface unit 3 and the object control unit 4. Corresponding to user input of a first or second instruction, the laser measurement control unit 5 analyzes the image information (IMG) or block information of the sampled area with a second priority analysis level and determines the laser measurement-related parameters of the sampled area.
[0043] Similar to the first embodiment, in this embodiment, the human-machine interface unit 3 may also include a second fully automatic mode module, and the second fully automatic mode module includes a second fully automatic mode. Specifically, as... Figure 7As shown, in the second fully automatic mode, the second fully automatic mode module of the human-machine interface unit 3 automatically determines and records whether each block has a first priority analysis level based on the analysis results of the processing unit 2. Then, it automatically records the sampling area with a second priority analysis level and transmits it to the laser measurement control unit 5. The laser measurement control unit 5 analyzes the image information (IMG) or block information of the sampling area with the second priority analysis level, automatically determines whether to record the sampling area with a third priority analysis level, and transmits a second fully automatic control signal (ACS2) to the object control unit 4 to control the displacement of the sampling area and perform Raman spectroscopy analysis based on the image information (IMG) or block information of the sampling area. In other words, in the second fully automatic mode, the human-machine interface unit 3 and the laser measurement control unit 5 can automatically complete all Raman spectroscopy detection processes. It should be noted that the determination of the first priority analysis level here is, for example, based on the analysis of image information IMG or block information to identify whether there are or a sufficient number of samples in the block; the determination of the second priority analysis level is, for example, based on the analysis of image information IMG or block information to identify the sample density in the block; and the determination of the third priority analysis level is, for example, based on the analysis of image information IMG or block information to identify the color, grayscale distribution, etc. in the block. However, the present invention is not limited thereto, and the criteria for determining the first, second, and third priority analysis levels can be changed according to the user's needs.
[0044] In this embodiment, the human-machine interface unit 3 may further include a third mode module and a fourth mode module. The third mode module includes a third mode, which is a semi-automatic measurement mode, and the first half of the program in the third mode implicitly includes the first mode, or in other words, the second half of the program in the third mode can be connected in series with the first mode. The fourth mode module includes a fourth mode, and the fourth mode is a user manual measurement mode.
[0045] like Figure 8As shown, in the third mode, the third mode module of the human-machine interface unit 3 automatically determines and records whether each block has a first priority analysis level based on the analysis results of the processing unit 2, and provides a third instruction to the user. For the user input corresponding to the third instruction, the third mode module of the human-machine interface unit 3 automatically records the sampling area with a second priority analysis level and transmits it to the third mode module of the human-machine interface unit 3. The third mode module of the human-machine interface unit 3 then transmits the image information (IMG) or block information of the sampling area with the second priority analysis level to the laser measurement control unit 5. The laser measurement control unit 5 analyzes the image information (IMG) or block information of the sampling area with the second priority analysis level and determines whether the sampling area has a third priority analysis level. Next, the laser measurement control unit 5 transmits a third instruction signal to the third mode module of the human-machine interface unit 3. The third mode module of the human-machine interface unit 3 automatically records the sampling area with the third priority analysis level and transmits a third control signal CS3 to the material control unit 4 so that the material control unit 4 controls the sampling area with the third priority analysis level to move and performs Raman spectroscopy analysis based on the image information IMG or block information of the sampling area.
[0046] like Figure 9As shown, in the fourth mode, the fourth mode module of the human-machine interface unit 3 receives a user input (corresponding to the user's desired selection of a sampling area) and determines that the sampling area has a second priority analysis level. The laser measurement control unit 5 analyzes the image information (IMG) or block information of the sampling area with the second priority analysis level and determines whether the sampling area has a third priority analysis level. Next, the laser measurement control unit 5 transmits a fourth indication signal to the fourth mode module of the human-machine interface unit 3, which provides a fourth indication to the user. Then, in response to a user input corresponding to the fourth indication, the fourth mode module of the human-machine interface unit 3 determines whether the sampling area has a third priority analysis level and transmits a fourth control signal CS4 to the object control unit 4 based on whether the sampling area has a third priority analysis level. The object control unit 4 then controls the position of the object M to be measured, causing the sampling area with the third priority analysis level to shift, and performs Raman spectroscopy analysis based on the image information (IMG) or block information of the sampling area. In one embodiment, the fourth instruction provided by the fourth mode module of the human-machine interface unit 3 is "based on the image information IMG or block information of the area range having a third priority analysis level". Therefore, the content of the fourth instruction can be "suggesting the user to determine that the recorded sampling area has a third priority analysis level". In another embodiment, the fourth instruction provided by the fourth mode module of the human-machine interface unit 3 is "based on the image information IMG or block information of the area range not having a third priority analysis level". Therefore, the content of the fourth instruction can be "suggesting the user not to record that the sampling area has a third priority analysis level". However, the user may also choose not to follow the content of the fourth instruction and determine whether to input the corresponding user instruction according to their needs. The user may also reselect the sampling area and execute the operation of the fourth mode again. Furthermore, the fourth instruction can be adjusted according to actual needs, and the present invention is not limited thereto.
[0047] However, the examples given above are merely one possible embodiment and are not intended to limit the invention.
[0048] [Third Embodiment]
[0049] The difference between the third embodiment and the first or second embodiment lies in the cleaning control unit; that is, the device for controlling the Raman spectrometer of the present invention may have a cleaning control unit. Furthermore, it should be noted that the other structures of the device D for controlling the Raman spectrometer provided in the third embodiment are similar to those of the aforementioned first or second embodiment, and will not be described again here.
[0050] See Figure 10As shown, in this embodiment, the device D for controlling a Raman spectrometer provided by the present invention may further include a cleaning control unit 6. The cleaning control unit 6 is electrically connected to the human-machine interface unit 3.
[0051] In one embodiment, the cleaning control unit 6 can automatically transmit a cleaning control signal CCS to a cleaning unit located within the Raman spectrometer after each startup of the Raman spectrometer, so that the cleaning unit cleans a detection space within the Raman spectrometer. The cleaning unit may include an ultraviolet module, but the invention is not limited thereto.
[0052] In one embodiment, the human-machine interface unit 3 may further include a fifth mode module, and the fifth mode module includes a fifth mode. For example... Figure 11 As shown, in the fifth mode, after each time the stage retracts from the detection space of the Raman spectrometer, the cleaning control unit 6 can transmit a fifth indication signal to the fifth mode module of the human-machine interface unit 3 based on the number of times the substrate carrying the analyte M is used, the number of times the stage enters and exits the detection space of the Raman spectrometer, or the duration of continuous operation of the Raman spectrometer. The fifth mode module of the human-machine interface unit 3 provides a fifth indication based on the fifth indication signal. For a user input corresponding to the fifth indication, the fifth mode module of the human-machine interface unit 3 determines whether to transmit a fifth control signal CS5 to the cleaning control unit 6, so that the cleaning control unit 6 transmits a cleaning control signal CCS to the cleaning unit within the Raman spectrometer to clean the detection space within the Raman spectrometer.
[0053] However, the examples given above are merely one possible embodiment and are not intended to limit the invention.
[0054] Furthermore, the aforementioned first mode module, second mode module, third mode module, fourth mode module, and fifth mode module can be software, firmware, hardware, or other combinations of software, firmware, and hardware that can achieve the above functions.
[0055] [Beneficial Effects of the Examples]
[0056] One of the beneficial effects of the present invention is that the device for controlling a Raman spectrometer provided by the present invention can enhance the human-computer interaction between the user and the Raman spectrometer, improve the control of the Raman spectrometer, reduce measurement time, and optimize detection results through the technical solution of "an image acquisition and analysis unit for acquiring image information of a analyte and dividing the image information into multiple blocks, each block having corresponding block information; a processing unit for comparing one block information with a predetermined image information value range or threshold value to determine whether the corresponding block has a first priority analysis level; and a human-machine interface unit for receiving user input for each block having a first priority analysis level to record whether each block has a second priority analysis level".
[0057] The content disclosed above is only a preferred and feasible embodiment of the present invention, and is not intended to limit the claims of the present invention. Therefore, all equivalent technical changes made based on the content of the present invention specification and drawings are included within the scope of the claims of the present invention.
Claims
1. A device for controlling a Raman spectrometer, characterized in that, The device for controlling a Raman spectrometer includes: an image acquisition and analysis unit configured to acquire image information of a test object and divide the image information into a plurality of blocks, each of the blocks having corresponding block information; a processing unit electrically connected to the image acquisition and analysis unit, the processing unit comparing one of the block information with a predetermined image information numerical range or threshold value to determine whether the corresponding block has a first priority analysis level; a human-machine interface unit electrically connected to the image acquisition and analysis unit and the processing unit, the human-machine interface unit receiving a user input for each of the blocks having the first priority analysis level to record whether each of the blocks has a second priority analysis level; the human-machine interface unit includes a first mode module and a second mode module, the first mode module includes a first mode; in the first mode, the first mode module provides a first indication to a user for each of the blocks having the first priority analysis level, and the first mode module automatically records whether each of the blocks has the second priority analysis level corresponding to the user input corresponding to the first indication; the second mode module includes a second mode, in the second mode, the second mode module provides a second indication to the user for whether each of the blocks determined by the user has the first priority analysis level, and the second mode module determines whether to record whether each of the blocks determined by the user has the second priority analysis level corresponding to a user input corresponding to the second indication; A laser measurement control unit is electrically connected to the human-machine interface unit; wherein, the human-machine interface unit includes a third mode module and a fourth mode module; the third mode module includes a third mode, in which the third mode module provides a third indication to the user for each of the blocks having the first priority analysis level, and the third mode module automatically records whether each of the blocks corresponding to the third indication has the second priority analysis level for the user input correspondingly and transmits the block information having the second priority analysis level to the laser measurement control unit, and the laser measurement control unit analyzes and determines whether the block information having the second priority analysis level has the third priority analysis level and transmits the block information having the third priority analysis level to the third mode module, and the third mode module automatically records whether each block has the third priority analysis level correspondingly; the fourth mode module includes a fourth mode, in which the fourth mode module transmits the block information determined by each user to have the second priority analysis level to the laser measurement control unit, and the laser measurement control unit analyzes and determines whether the block information having the second priority analysis level has the third priority analysis level and transmits it to the fourth mode module, and the fourth mode module provides a fourth indication to the user for whether each of the blocks determined by the user has the third priority analysis level, and the fourth mode module records whether each of the blocks corresponding to the fourth indication has the third priority analysis level for the user input correspondingly; and A load control unit is electrically connected to the human-machine interface unit and the laser measurement control unit, and controls the position of the test object for the block having the third priority analysis level and performs Raman spectroscopy detection on the block having the third priority analysis level.
2. The device for controlling a Raman spectrometer according to claim 1, wherein When the processing unit compares the block information with the predetermined image information numerical range or threshold value to determine whether the corresponding block has the first priority analysis level, when the block information falls within the predetermined image information numerical range, the processing unit determines that the corresponding block has the first priority analysis level, and when the block information does not fall within the predetermined image information numerical range, the processing unit determines that the corresponding block does not have the first priority analysis level.
3. The device for controlling a Raman spectrometer according to claim 1 or 2, characterized in that, The device for controlling the Raman spectrometer further includes: A cleaning control unit is electrically connected to the human-machine interface unit.
4. The device for controlling a Raman spectrometer according to claim 3, wherein, The cleaning control unit performs an automatic control to clean a detection space inside the Raman spectrometer.
5. The device for controlling a Raman spectrometer according to claim 4, characterized in that, The human-machine interface unit includes a fifth mode module, and the fifth mode module includes a fifth mode. In the fifth mode, the fifth mode module provides a fifth indication to the user for the number of uses of a substrate carrying the object to be measured, the number of times the stage of the Raman spectrometer enters and exits the detection space of the Raman spectrometer, or the duration of the continuous startup state of the Raman spectrometer. The fifth mode module determines whether to clean the detection space of the Raman spectrometer correspondingly according to a user input corresponding to the fifth indication.