A patch-type infusion pump and an infusion method

Abstract

The present invention discloses a patch-type infusion pump and an infusion method. The infusion tube of the patch-type infusion pump is used to transport liquid drugs. The valve mechanism of the infusion component includes a pressing valve, a shape memory alloy member, and a reset elastic body. The shape memory alloy member is connected to the pressing valve, and the pressing valve presses against the infusion tube. When the shape memory alloy member is energized, it can contract and drive the pressing valve to move away from the infusion tube. After the shape memory alloy member is de-energized, the pressing valve can be reset to the position of pressing against the infusion tube under the drive of the reset elastic body. The shape memory alloy members of multiple valve mechanisms of the patch-type infusion pump perform energization operations and de-energization operations in a preset order, so that the infusion tube deforms and negative pressure and positive pressure are successively generated in the infusion tube. Under the negative pressure operation, the infusion tube sucks liquid drugs from the liquid storage mechanism, and under the positive pressure action, the infusion tube pumps out liquid drugs to the drug output mechanism. Compared with the existing patch-type infusion pumps, the patch-type infusion pump of the present invention is small in size and light in weight.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a patch-type infusion pump and an infusion method. Background Art

[0002] Diabetes has become a global public health problem affecting human health. As an effective means for diabetes patients to manage blood sugar, an insulin pump is a tool for subcutaneous insulin injection with micro-precision and continuous controllability, and it can better simulate the secretion pattern of physiological insulin. Existing insulin pumps mainly include two types: a tube pump and a patch pump. Among them, the tube pump consists of a pump body, a drug reservoir, and an infusion set with a tube. The infusion set is applied to the patient's skin surface and connected to the pump body through an external tube. The pump body uses a reduction motor to drive the piston of the infusion mechanism, thereby realizing the flow of insulin in the infusion set. The technology of the tube pump has been very mature, but due to the influence of the external tube and the bulky pump body, patients need to pay close attention at all times during use, which seriously affects the wearing experience.

[0003] The patch pump, also known as a catheter-free pump, is smaller and lighter in volume compared to the tube pump. Therefore, the entire patch pump can be directly applied to the patient's skin surface for infusion treatment, which is convenient for patients to use and basically does not affect daily activities during wearing, improving the patient's use experience to a certain extent.

[0004] However, since the patch pump needs to be worn for a long time, patients have higher requirements for the volume and weight of the product. The infusion mechanism is an important component of the patch pump, and its structure is the key factor restricting the further reduction of the volume and weight of the patch pump. Existing infusion mechanisms either use a smaller micro-reduction motor based on the infusion scheme of the tube pump, or use an SMA-driven reduction gear to replace the motor to push the piston. The contributions of both methods to reducing the volume and weight of the patch pump are limited and cannot meet the requirements of users for the volume and weight of the patch pump. Summary of the Invention

[0005] The first object of the present invention is to provide a patch-type infusion pump, which is small in volume, light in weight, and has a good use experience for users wearing it for a long time.

[0006] To achieve this purpose, the present invention adopts the following technical solutions:

[0007] A patch-type infusion pump, comprising: an infusion tube for conveying liquid medicine; an infusion assembly, the infusion assembly includes a plurality of valve mechanisms arranged on the side of the infusion tube, the plurality of valve mechanisms are arranged at intervals along the flow direction of the liquid medicine in the infusion tube, each valve mechanism includes a pressing valve, a shape memory metal piece and a reset elastic body, the pressing valve presses on the infusion tube to block the flow of the liquid medicine in the infusion tube, the shape memory metal piece can contract when electrified and drive the pressing valve to move away from the infusion tube, and after the shape memory metal piece is powered off, the pressing valve can be reset to the position pressing the infusion tube under the drive of the reset elastic body; wherein: the shape memory metal pieces of the plurality of valve mechanisms perform energization operations and power-off operations in a preset order, so that the infusion tube deforms and negative pressure and positive pressure are successively generated in the infusion tube. Under the negative pressure operation, the infusion tube sucks the liquid medicine from the liquid storage mechanism, and under the positive pressure action, the infusion tube pumps the liquid medicine to the drug output mechanism.

[0008] Preferably, the infusion assembly further includes a base, the base includes a plurality of channel plates, a valve channel is formed between two adjacent channel plates, and each pressing valve is movably placed in a valve channel.

[0009] Preferably, the base further includes a pipeline baffle, the pipeline baffle is arranged on one side of the plurality of channel plates, the plurality of channel plates are arranged at intervals from the channel plates, and the infusion tube is limited between the pipeline baffle and the plurality of channel plates.

[0010] Preferably, the base further includes a limiting plate, the limiting plate is arranged on the other side of the plurality of channel plates, and a plurality of limiting holes are arranged on the limiting plate; the pressing valve includes a valve pressing head and a valve guide rod connected to each other, the valve pressing head is used to press the infusion tube, and the valve guide rod is arranged in the limiting holes.

[0011] Preferably, the pressing valve further includes a valve connecting seat, the valve connecting seat is connected between the valve pressing head and the valve guide rod; the reset elastic body is a spiral spring, the spiral spring is sleeved on the valve guide rod, and one end of the spiral spring is in limit contact with the valve connecting seat, and the other end of the spiral spring is in limit contact with the limiting plate.

[0012] Preferably, the infusion assembly further includes an infusion cover plate, the infusion cover plate is fixedly arranged on the base; the shape memory metal piece includes a positive electrode elastic piece, a shape memory metal wire and a negative electrode elastic piece connected in sequence, and one of the positive electrode elastic piece and the negative electrode elastic piece is connected to the pressing valve, and the other is connected to the infusion cover plate.

[0013] Preferably, the infusion assembly further includes a guide post, and a limiting guide groove is circumferentially arranged on the guide post; the infusion cover plate and the pressing valve are arranged up and down, the guide post is located on one side of the infusion cover plate and the pressing valve, the shape memory wire is wound around the guide post, and the shape memory wire is placed in the limiting guide groove.

[0014] Preferably, the infusion assembly further includes a grounding shrapnel, the patch infusion pump further includes a circuit board, the positive shrapnel is electrically connected to the circuit board, and the negative shrapnel is electrically connected to the circuit board through the grounding shrapnel.

[0015] Preferably, the patch infusion pump further includes a housing, the liquid storage mechanism, the power supply mechanism and the drug output mechanism. An installation cavity is formed in the housing. The infusion assembly, the liquid storage mechanism and the power supply mechanism are all arranged in the installation cavity. The liquid inlet end of the infusion tube is communicated with the liquid storage mechanism, the liquid outlet end of the infusion tube is communicated with the drug output mechanism, and the power supply mechanism is used to supply power to the patch infusion pump.

[0016] The second object of the present invention is to provide an infusion method, which has high reliability and high precision in infusing liquid drugs.

[0017] To achieve this purpose, the present invention adopts the following technical solutions:

[0018] An infusion method using the above-mentioned patch infusion pump. The infusion assembly of the patch infusion pump includes an infusion tube and a plurality of valve mechanisms. Along the flow direction of the liquid drug in the infusion tube, the plurality of valve mechanisms include a first valve mechanism located at the uppermost stream, a third valve mechanism located at the lowermost stream, and a second valve mechanism located between the first valve mechanism and the third valve mechanism; the infusion method includes the following steps: the infusion assembly completes an infusion operation in the order of energizing the shape memory member of the first valve mechanism, energizing the shape memory member of the second valve mechanism, de-energizing the shape memory member of the first valve mechanism, energizing the shape memory member of the third valve mechanism, de-energizing the shape memory member of the second valve mechanism, and de-energizing the shape memory member of the third valve mechanism.

[0019] The beneficial effects of the present invention:

[0020] The patch-type infusion pump provided by the present invention includes an infusion tube and an infusion assembly. The infusion tube is used to transport liquid medicine. The valve mechanisms of the infusion assembly all include a pressing valve, a shape memory alloy part, and a reset elastic body. One end of the shape memory alloy part is fixedly arranged, and the other end of the shape memory alloy part is connected to the pressing valve. The pressing valve presses against the infusion tube to block the flow of the liquid medicine in the infusion tube. When the shape memory alloy part is electrified, it can contract and drive the pressing valve to move away from the infusion tube. After the shape memory alloy part is powered off, the pressing valve can be reset to the position where it presses against the infusion tube under the drive of the reset elastic body. The shape memory alloy parts of multiple valve mechanisms of the patch-type infusion pump perform electrification operations and power-off operations in a preset order, so that the infusion tube deforms and negative pressure and positive pressure are successively generated in the infusion tube. Under the negative pressure operation, the infusion tube sucks the liquid medicine from the liquid storage mechanism, and under the positive pressure action, the infusion tube pumps the liquid medicine to the drug output mechanism. Compared with the existing patch-type infusion pumps, this patch-type infusion pump is small in size and light in weight. Description of the Drawings

[0021] Figure 1 is an exploded view of the patch-type infusion pump provided by an embodiment of the present invention;

[0022] Figure 2 is a top view of a partial structure of the patch-type infusion pump provided by an embodiment of the present invention;

[0023] Figure 3 is an exploded view of a partial structure of the patch-type infusion pump provided by an embodiment of the present invention;

[0024] Figure 4 is a cross-sectional view of the patch-type infusion pump provided by an embodiment of the present invention;

[0025] Figure 5 is a schematic diagram of the pressing valve of the patch-type infusion pump provided by an embodiment of the present invention;

[0026] Figure 6 is a schematic diagram of the shape memory alloy part of the patch-type infusion pump provided by an embodiment of the present invention;

[0027] Figure 7 is a schematic diagram of the grounding spring piece of the patch-type infusion pump provided by an embodiment of the present invention.

[0028] In the figure:

[0029] 1. Infusion assembly;

[0030] 110. Pressure valve; 111. Valve head; 112. Valve guide rod; 113. Valve connection seat; 114. Second convex post; 120. Shape memory metal part; 121. Positive electrode elastic piece; 122. Shape memory wire; 123. Negative electrode elastic piece; 130. Reset elastic body; 140. Base; 141. Bottom plate; 142. Channel plate; 143. Pipeline baffle; 144. Limit plate; 1441. Limit hole; 150. Infusion cover plate; 151. First convex post; 160. Guide post; 161. Limit guide groove; 170. Grounding elastic piece; 171. Common ground bottom plate; 172. Common ground elastic pin

[0031] 2. Infusion tube

[0032] 3. Housing

[0033] 4. Liquid storage mechanism

[0034] 5. Circuit board

[0035] 6. Power supply mechanism

[0036] 7. Puncture needle driving part

[0037] 8. Puncture needle Detailed implementation mode

[0038] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some, but not all, of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0039] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance. Among them, the terms "first position" and "second position" are two different positions.

[0040] In the description of the present invention, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", and "coupling" should be understood in a broad sense. For example, it can be a fixed connection or a detachable connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0041] The present invention provides a patch-type infusion pump that can be attached to a patient's body and pump insulin into the patient's body. Of course, in addition to insulin, the patch-type infusion pump can also be used to pump other liquid drugs into the patient's body.

[0042] As Figures 1 to 4 shown, the patch-type infusion pump includes an infusion tube 2 and an infusion assembly 1. The infusion tube 2 is used to transport liquid drugs, such as insulin. The infusion assembly 1 includes a plurality of valve mechanisms arranged on the side of the infusion tube 2, and the plurality of valve mechanisms are arranged at intervals along the flow direction of the liquid drug in the infusion tube 2. It should be noted that the plurality of valve mechanisms can be located on the same side of the infusion tube 2 or on different sides of the infusion tube 2. Each valve mechanism includes a pressing valve 110, a shape memory metal member 120, and a reset elastic body 130. The pressing valve 110 presses on the infusion tube 2 to block the flow of the liquid drug in the infusion tube 2. The shape memory metal member 120 is a long member made of shape memory metal. The shape memory metal is a special metal material that undergoes plastic deformation within a certain temperature range and can restore its original macroscopic shape within another temperature range. When the shape memory metal member 120 is energized, it can contract and drive the pressing valve 110 to move away from the infusion tube 2. After the shape memory metal member 120 is de-energized, the pressing valve 110 can be reset to the position pressing on the infusion tube 2 under the drive of the reset elastic body 130. The shape memory metal members 120 of the plurality of valve mechanisms perform energization operations and de-energization operations in a preset order, so that the infusion tube 2 deforms and generates negative pressure and positive pressure in the infusion tube 2 successively. Under the negative pressure operation, the infusion tube 2 sucks the liquid drug from the liquid storage mechanism 4, and under the positive pressure action, the infusion tube 2 pumps the liquid drug to the drug output mechanism.

[0043] Specifically, in the flow direction of the liquid medicine in the infusion tube 2, the multiple valve mechanisms include a first valve mechanism located at the uppermost stream, a third valve mechanism located at the lowermost stream, and a second valve mechanism located in the middle. When the pressing valve 110 of the third valve mechanism at the lowermost stream is in a state of pressing the infusion tube 2, the shape memory metal parts 120 of the first valve mechanism and the second valve mechanism located upstream thereof are energized in sequence, and the corresponding pressing valves 110 move away from the infusion tube 2, which can form a negative pressure in the infusion tube 2. Under the action of the negative pressure, the infusion tube 2 sucks the liquid medicine to the next valve mechanism. Then, the shape memory metal part 120 of the first valve mechanism at the uppermost stream is powered off, and the corresponding pressing valve 110 presses against the infusion tube 2 again to stop the infusion tube 2 from sucking the liquid medicine. Then, the shape memory metal part 120 of the third valve mechanism at the lowermost stream is energized, and the corresponding pressing valve 110 moves away from the infusion tube 2, which can conduct the infusion tube 2 with the medicine output mechanism. Finally, when the pressing valve 110 of the first valve mechanism at the uppermost stream is in a state of pressing the infusion tube 2 again, the shape memory metal parts 120 of the second valve mechanism and the third valve mechanism located downstream thereof are powered off in sequence, and the corresponding pressing valves 110 press against the infusion tube 2 again, which can form a positive pressure in the infusion tube 2. Under the action of the positive pressure, the infusion tube 2 can pump out the liquid medicine.

[0044] Compared with the existing infusion pumps, the patch-type infusion pump provided by the present invention cancels the traditional speed reduction transmission mechanism and piston components, so that not only the volume and weight of the patch-type infusion pump can be greatly reduced, meeting the needs of patients and improving the wearing experience of patients, but also the assembly of the patch-type infusion pump is simpler and more convenient. In addition, the coordinated actions between the multiple valve mechanisms of the patch-type infusion pump obtain higher infusion accuracy, and the blocking of the multi-channel valve mechanisms on the infusion tube 2 when not in operation makes the liquid medicine reliably isolated from the human body, with higher safety.

[0045] In some embodiments, with continued reference to Figure 3 shown in the figure, the infusion assembly 1 further includes a base 140, and the base 140 is used to mount the infusion tube 2 and the multiple valve mechanisms. The base 140 includes a bottom plate 141 and a plurality of channel plates 142 arranged on the bottom plate 141. The plurality of channel plates 142 are arranged in parallel, and each channel plate 142 is arranged along a direction perpendicular to the infusion tube 2. A valve channel is formed between two adjacent channel plates 142. The number of valve channels is the same as the number of valve mechanisms. Each pressing valve 110 is movably placed in a valve channel, and the valve channel is used to guide the movement of the pressing valve 110.

[0046] In a specific embodiment, the patch-type infusion pump is provided with three valve mechanisms. Correspondingly, four channel plates 142 are provided on the base 140, and three valve channels are formed between the four channel plates 142. In other specific embodiments, the number of valve mechanisms can be set to four, five or more according to requirements. Correspondingly, the number of channel plates 142 can be increased to form more valve channels.

[0047] To limit the position of the infusion tube 2 so that the valve mechanism can precisely press against or disengage from the infusion tube 2, continue to refer to Figure 3 As shown, the base 140 further includes a pipeline baffle 143. The pipeline baffle 143 is provided on one side of the plurality of channel plates 142. The plurality of channel plates 142 are arranged at intervals with the channel plates 142 and form a space for accommodating the infusion tube 2. The infusion tube 2 is limited between the pipeline baffle 143 and the plurality of channel plates 142. In some embodiments, the wall thickness of the infusion tube 2 is less than 0.5 mm.

[0048] To further improve the movement accuracy of the pressing valve 110, continue to refer to Figure 3 As shown, the base 140 further includes a limiting plate 144. The limiting plate 144 is provided on the other side of the plurality of channel plates 142. A plurality of limiting holes 1441 are provided on the limiting plate 144, and the number of the limiting holes 1441 is the same as the number of valve mechanisms. As Figure 5 shown, the pressing valve 110 includes a valve pressing head 111 and a valve guide rod 112 connected to each other. The valve pressing head 111 is used to press against the infusion tube 2. The valve guide rod 112 is inserted into the limiting hole 1441, and the valve guide rod 112 can move in the limiting hole 1441, thereby improving the movement accuracy of the valve mechanism. In a specific embodiment, the number of valve guide rods 112 is three. Correspondingly, the number of limiting holes 1441 provided on the limiting plate 144 is also three. In a specific embodiment, the valve guide rod 112 is a cylindrical rod, and the limiting hole 1441 is a circular hole. Of course, the cross-sections of the valve guide rod 112 and the limiting hole 1441 can also be other shapes.

[0049] In some embodiments, continue to refer to Figure 5As shown, the pressing valve 110 further includes a valve connecting seat 113, and the valve connecting seat 113 is connected between the valve pressing head 111 and the valve guide rod 112. The reset elastic body 130 is a helical spring. The helical spring is sleeved on the valve guide rod 112, and one end of the helical spring is in limiting abutment with the valve connecting seat 113, and the other end of the helical spring is in limiting abutment with the limiting plate 144. In this way, the fixing and limiting of the helical spring can be realized. In a specific embodiment, the valve connecting seat 113 is an L-shaped plate, and one end of the valve guide rod 112 is connected to the inner wall surface of the vertical plate of the valve connecting seat 113; the pressing valve 110 is an L-shaped plate, and the pressing valve 110 is connected to the outer wall surface of the valve connecting seat 113.

[0050] Continue to refer to Figure 4 As shown, one end of the shape memory metal member 120 is fixedly arranged. Here, the fixed arrangement means that one end of the shape memory metal member 120 is fixed to other mechanisms so that one end of the shape memory metal member 120 cannot move. The other end of the shape memory metal member 120 is connected to the pressing valve 110. Here, the connection can be a direct fixed connection or an abutment realized through a rotatable cam. When the shape memory metal member 120 is directly connected to the pressing valve 110, the shape memory metal member 120 shrinks and directly pulls the pressing valve 110 to move; when the shape memory metal member 120 is rotationally abutted against the pressing valve 110 through a cam, the shape memory metal member 120 deforms to drive the cam to rotate, and different parts of the cam abutting against the pressing valve 110 can make the pressing valve 110 move.

[0051] In some embodiments, as Figure 6 shown, the shape memory metal member 120 includes a positive electrode elastic sheet 121, a shape memory metal wire 122 and a negative electrode elastic sheet 123 connected in sequence. The shape memory metal wire 122 is a filamentous structure made of shape memory metal, and both the positive electrode elastic sheet 121 and the negative electrode elastic sheet 123 are made of conductive materials. In order to realize the fixing of one end of the shape memory metal member 120, continue to refer to Figure 3 and Figure 4 shown, the infusion assembly 1 further includes an infusion cover plate 150. The infusion cover plate 150 is fixedly arranged on the base 140. For example, it can be fixedly connected to the pipeline baffle 143. One of the positive electrode elastic sheet 121 and the negative electrode elastic sheet 123 is connected to the pressing valve 110, and the other is connected to the infusion cover plate 150.

[0052] In one embodiment, the positive electrode elastic sheet 121 and the negative electrode elastic sheet 123 have the same structure. The positive electrode elastic sheet 121 is connected to the infusion cover plate 150, and the negative electrode elastic sheet 123 is connected to the valve connection seat 113 of the pressing valve 110. In order to achieve the quick connection between the positive electrode elastic sheet 121 and the infusion cover plate 150, a first insertion hole is provided on the positive electrode elastic sheet 121, and a first convex column 151 is provided on the infusion cover plate 150. The first convex column 151 can be inserted into the first insertion hole. In order to achieve the quick connection between the negative electrode elastic sheet 123 and the valve connection seat 113, a second insertion hole is provided on the negative electrode elastic sheet 123, and a second convex column 114 is provided on the valve connection seat 113. The second convex column 114 can be inserted into the second insertion hole.

[0053] In order to reduce the area occupied when the patch infusion pump is attached to the patient without shortening the movable distance of the pressing valve 110, continue to refer to Figure 3 and Figure 4 As shown, the infusion assembly 1 further includes a guide post 160. The guide post 160 is fixed above the channel plate 142 and directly above the limit plate 144. A limit guide groove 161 is provided on the guide post 160 along the circumferential direction. The infusion cover plate 150 and the pressing valve 110 are arranged up and down. The guide post 160 is located on one side of the infusion cover plate 150 and the pressing valve 110. The shape memory wire 122 is arranged around the guide post 160, and the shape memory wire 122 is placed in the limit guide groove 161. Such an arrangement folds the shape memory wire 122 into two parts, one part is located above the guide post 160, and the other part is located below the guide post 160. In this way, the lateral dimension of the patch infusion pump can be reduced, and the area occupied when the patch infusion pump is attached to the patient is reduced. In some embodiments, the guide post 160 is a semi-cylinder, and the limit guide groove 161 is provided on the semi-cylindrical surface of the guide post 160.

[0054] In order to perform power supply operation and power-off operation on the shape memory body, continue to refer to Figure 3 and Figure 4 As shown, the infusion assembly 1 further includes a grounding elastic sheet 170. The patch infusion pump further includes a circuit board 5, that is, a PCB board. The circuit board 5 is arranged above the infusion cover plate 150. The positive electrode elastic sheet 121 is directly electrically connected to the circuit board 5. A part of the grounding elastic sheet 170 is located between the pressing valve 110 and the infusion cover plate 150, and the other part of the grounding elastic sheet 170 bypasses the infusion cover plate 150 and is located above the infusion cover plate 150 and electrically connected to the circuit board 5. That is, the negative electrode elastic sheet 123 is electrically connected to the circuit board 5 through the grounding elastic sheet 170.

[0055] In some embodiments, such as Figure 7As shown, the grounding spring 170 includes a common grounding base plate 171 and a common grounding spring foot 172. The common grounding base plate 171 is a rectangular plate and is located between the pressure valve 110 and the infusion cover plate 150. The common grounding spring foot 172 is an elastic curved plate that can be compressed and deformed, so that the common grounding base plate 171 can always maintain electrical connection with the circuit board 5 when the pressure valve 110 moves.

[0056] The circuit board 5 can be a centralized or distributed controller. For example, the circuit board 5 can be a single single-chip microcomputer or a distributed plurality of single-chip microcomputers. The single-chip microcomputer can run a control program to control the plurality of valve body mechanisms to realize the power on and off function in a preset sequence.

[0057] In order to protect the valve mechanism and other components disposed on the base 140, continue to refer to Figure 1 As shown, the patch-type infusion pump also includes a shell 3, which is buckled on the bottom plate 141 of the base 140. An installation cavity is formed between the shell 3 and the bottom plate 141, and components such as the valve body mechanism are arranged in the installation cavity.

[0058] Continue to refer to Figure 1 and Figure 2 As shown, the patch-type infusion pump also includes a liquid storage mechanism 4 and a drug output mechanism. The liquid storage mechanism 4 is arranged in the installation cavity and fixed on the bottom plate 141 of the base 140. The liquid storage mechanism 4 has a liquid storage cavity for storing liquid drugs. The liquid storage mechanism 4 is connected to the liquid inlet end of the infusion tube 2, and the liquid drug in the liquid storage cavity can flow into the liquid storage tube. The drug output mechanism is used to output liquid drugs. In some embodiments, the drug output mechanism includes a puncture needle driver 7 and a puncture needle 8. The puncture needle driver 7 is arranged in the installation cavity and fixed on the bottom plate 141 of the base 140. The puncture needle 8 is connected to the output end of the infusion tube 2. The puncture needle driver 7 is used to drive the puncture needle 8 to move so that the puncture needle 8 can penetrate into or leave the patient's body.

[0059] In a specific embodiment, the puncture needle driving member 7 is rotatably connected to the bottom plate 141, a spiral groove is circumferentially provided on the puncture needle driving member 7, and a protrusion is provided on the puncture needle 8, and the protrusion is placed in the spiral groove. Driving the puncture needle driving member 7 to rotate can drive the protrusion to rise and fall in the vertical direction, thereby realizing the up and down movement of the puncture needle 8. The rotation power of the puncture needle driving member 7 can come from manual drive or from a power member such as a motor.

[0060] Continue to refer to Figure 1 and Figure 2As shown, the patch-type infusion pump further includes a power supply mechanism 6. The power supply mechanism 6 is placed in the installation cavity and fixedly connected to the bottom plate 141. The power supply mechanism 6 is used to supply power to the electrical components of the patch-type infusion pump, and the electrical components can be the puncture needle driving member 7, the circuit board 5, etc. In some embodiments, the power supply mechanism 6 is a button battery, such as an LR44 button battery, and three LR44 button batteries can be used according to requirements; in some embodiments, the power supply mechanism 6 is a battery pack, such as a lithium-ion battery pack.

[0061] The working principle of the patch-type infusion pump is as follows:

[0062] When the patch-type infusion pump needs to perform infusion, the shape memory alloy member 120 of the valve mechanism is electrified and contracted. The shape memory alloy member 120 pulls the pressing valve 110 away from the infusion tube 2. During this process, the helical spring is compressed, and the infusion tube 2 that was originally deformed by the extrusion of the pressing valve 110 resumes its own shape, generating negative pressure to suck the medicine. When the shape memory alloy member 120 is powered off, the pressing valve 110 moves in the direction close to the infusion tube 2 under the action of the helical spring. The pressing valve 110 cooperates with the pipeline baffle 143 to squeeze the infusion tube 2 again, and the volume of the infusion tube 2 decreases to generate positive pressure to pump out the medicine. The multi-channel valve mechanism of the patch-type infusion pump cooperates to open and close in a specific time sequence, so as to reliably and accurately infuse the medicine. And in the non-infusion state, under the action of the helical spring, the pressing valve 110 always presses on the infusion tube 2 to ensure the isolation of the medicine and the human body, greatly improving the safety.

[0063] The present invention also provides an infusion method, which uses the above-mentioned patch-type infusion pump.

[0064] Along the flow direction of the liquid medicine in the infusion tube 2, for the convenience of description, the valve mechanism located at the most upstream among the multiple valve mechanisms is called the first valve mechanism, the valve mechanism located at the most downstream among the multiple valve mechanisms is called the third valve mechanism, and the valve mechanism located between the first valve mechanism and the third valve mechanism is called the second valve mechanism. The number of the second valve mechanisms can be set to one, two or more according to requirements.

[0065] Taking the case of only having one second valve mechanism as an example, the infusion method includes the following steps:

[0066] The infusion assembly 1 energizes the shape memory alloy member 120 of the first valve mechanism (the liquid medicine flows to the second valve mechanism), energizes the shape memory alloy member 120 of the second valve mechanism (the liquid medicine flows to the third valve mechanism), de-energizes the shape memory alloy member 120 of the first valve mechanism (blocks the liquid inlet end of the liquid storage tube), energizes the shape memory alloy member 120 of the third valve mechanism (opens the liquid outlet end of the liquid storage tube), de-energizes the shape memory alloy member 120 of the second valve mechanism described above (the liquid medicine flows out of the second valve mechanism), and de-energizes the shape memory alloy member 120 of the third valve mechanism (the liquid medicine flows out of the third valve mechanism). In this way, an infusion operation can be completed sequentially.

[0067] It should be noted that a period of time needs to be interposed between each step to provide sufficient time for the flow of the liquid medicine.

[0068] When there are two or more second valves, for all the operation steps related to the second valve mechanism described above, the multiple second valve mechanisms can repeat the operation steps in sequence from upstream to downstream along the flow direction of the liquid medicine in the infusion tube 2. For example, for the operation step of "energizing the shape memory alloy member 120 of the second valve mechanism", it can be that the shape memory alloy member 120 of the second valve mechanism located at the uppermost upstream is energized along the flow direction of the liquid medicine in the infusion tube 2; then, the shape memory alloy member 120 of the next adjacent second valve mechanism is energized; finally, the shape memory alloy member 120 of the second valve mechanism located at the lowermost downstream is energized.

[0069] Of course, the multiple second valve mechanisms can also repeat the operation steps simultaneously. For example, for the operation step of "energizing the shape memory alloy member 120 of the second valve mechanism", it can be that the shape memory alloy members 120 of the multiple second valve mechanisms are energized simultaneously. It should be noted that during the process of the circuit board 5 controlling the valve mechanism, it is necessary to ensure that at least one valve mechanism is in a state of blocking the infusion tube 2 to ensure the safety of the patient and the reliability of the patch type infusion pump.

[0070] This infusion method can enable the liquid medicine to flow gradually in the direction close to the medicine output mechanism under the action of negative pressure, and the multiple valve mechanisms cooperate to open and close in a specific time sequence, so as to be able to infuse the medicine reliably and accurately.

[0071] Obviously, the above-mentioned embodiments of the present invention are only examples for clearly illustrating the present invention, rather than limitations on the implementation manners of the present invention. For those of ordinary skill in the art, other different forms of changes or modifications can be made on the basis of the above description. It is not necessary and impossible to enumerate all the implementation manners here. Any modifications, equivalent replacements, and improvements made within the spirit and principle of the present invention shall be included within the protection scope of the claims of the present invention.

Claims

1. A patch-type infusion pump, characterized in that, Comprising: An infusion tube (2) for delivering liquid medicine; An infusion assembly (1), the infusion assembly (1) includes a plurality of valve mechanisms arranged on the side of the infusion tube (2), the plurality of valve mechanisms are arranged at intervals along the flow direction of the liquid medicine in the infusion tube (2), and each valve mechanism includes a pressing valve (110), a shape memory metal member (120) and a reset elastic body (130). The pressing valve (110) presses on the infusion tube (2) to block the flow of the liquid medicine in the infusion tube (2). When the shape memory metal member (120) is energized, it can contract and drive the pressing valve (110) to move away from the infusion tube (2). After the shape memory metal member (120) is powered off, the pressing valve (110) can be reset to the position pressing the infusion tube (2) under the drive of the reset elastic body (130); wherein: The shape memory metal members (120) of the plurality of valve mechanisms perform energization operations and power-off operations in a preset order, so that the infusion tube (2) deforms and negative pressure and positive pressure are successively generated in the infusion tube (2). Under the negative pressure operation, the infusion tube (2) sucks the liquid medicine from the liquid storage mechanism (4), and under the positive pressure action, the infusion tube (2) pumps the liquid medicine to the drug output mechanism; Along the flow direction of the liquid medicine in the infusion tube (2), the plurality of valve mechanisms include a first valve mechanism located at the uppermost stream, a third valve mechanism located at the lowermost stream, and a second valve mechanism located between the first valve mechanism and the third valve mechanism. The infusion assembly (1) completes an infusion operation in the order of energizing the shape memory metal member (120) of the first valve mechanism, energizing the shape memory metal member (120) of the second valve mechanism, powering off the shape memory metal member (120) of the first valve mechanism, energizing the shape memory metal member (120) of the third valve mechanism, powering off the shape memory metal member (120) of the second valve mechanism, and powering off the shape memory metal member (120) of the third valve mechanism.

2. The patch type infusion pump according to claim 1, wherein The infusion assembly (1) further includes a base (140), the base (140) includes a plurality of channel plates (142), and a valve channel is formed between two adjacent channel plates (142), and each pressing valve (110) is movably disposed in one of the valve channels.

3. The patch type infusion pump according to claim 2, wherein The base (140) further includes a pipeline baffle (143), the pipeline baffle (143) is arranged on one side of the plurality of channel plates (142), the plurality of channel plates (142) are spaced apart from the pipeline baffle (143), and the infusion tube (2) is limited between the pipeline baffle (143) and the plurality of channel plates (142).

4. The patch type infusion pump according to claim 2, wherein The base (140) further includes a limit plate (144) disposed on the other side of the plurality of channel plates (142), and a plurality of limit holes (1441) are provided on the limit plate (144); The pressing valve (110) includes a valve head (111) and a valve guide rod (112) connected to each other. The valve head (111) is used to press the infusion tube (2), and the valve guide rod (112) is inserted into the limit hole (1441).

5. The patch type infusion pump according to claim 4, wherein The pressing valve (110) further includes a valve connection seat (113), and the valve connection seat (113) is connected between the valve head (111) and the valve guide rod (112); The reset elastic body (130) is a helical spring. The helical spring is sleeved on the valve guide rod (112), and one end of the helical spring is in limit abutment with the valve connection seat (113), and the other end of the helical spring is in limit abutment with the limit plate (144).

6. The patch type infusion pump according to claim 2, wherein The infusion assembly (1) further includes an infusion cover plate (150), and the infusion cover plate (150) is fixedly arranged on the base (140); The shape memory metal part (120) includes a positive electrode elastic sheet (121), a shape memory metal wire (122) and a negative electrode elastic sheet (123) connected in sequence. One of the positive electrode elastic sheet (121) and the negative electrode elastic sheet (123) is connected to the pressing valve (110), and the other is connected to the infusion cover plate (150).

7. The patch type infusion pump according to claim 6, wherein The infusion assembly (1) further includes a guide post (160), and a limit guide groove (161) is provided on the guide post (160) along the circumferential direction; The infusion cover plate (150) and the pressing valve (110) are arranged up and down. The guide post (160) is located on one side of the infusion cover plate (150) and the pressing valve (110). The shape memory metal wire (122) is arranged around the guide post (160), and the shape memory metal wire (122) is placed in the limit guide groove (161).

8. The patch type infusion pump according to claim 6, wherein The infusion assembly (1) further includes a grounding elastic sheet (170). The patch type infusion pump further includes a circuit board (5). The positive electrode elastic sheet (121) is electrically connected to the circuit board (5), and the negative electrode elastic sheet (123) is electrically connected to the circuit board (5) through the grounding elastic sheet (170).

9. The patch type infusion pump according to any one of claims 1-8, wherein The patch type infusion pump further includes a housing (3), the liquid storage mechanism (4), a power supply mechanism (6) and the drug output mechanism. An installation cavity is formed inside the housing (3). The infusion assembly (1), the liquid storage mechanism (4) and the power supply mechanism (6) are all disposed in the installation cavity. The liquid inlet end of the infusion tube (2) is communicated with the liquid storage mechanism (4), and the liquid outlet end of the infusion tube (2) is communicated with the drug output mechanism. The power supply mechanism (6) is used to supply power to the patch type infusion pump.

Images