A fluorescence imaging system, a fluorescence imaging method and a gene sequencer
CN116333871BActive Publication Date: 2026-07-07GUANGDONG RUNPENG BIOLOGICAL TECH CO LTD +1
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- GUANGDONG RUNPENG BIOLOGICAL TECH CO LTD
- Filing Date
- 2022-12-23
- Publication Date
- 2026-07-07
AI Technical Summary
Technical Problem
Existing fluorescence imaging systems have complex optical path structures, are difficult to manufacture, and are costly, making it difficult to effectively reduce the size and number of components in the optical system.
Method used
A fluorescence imaging system with dual-path excitation is adopted, using multiple single-pass single-reflective dichroic mirrors to achieve beam combining and splitting of excitation light and fluorescence, simplifying the optical path structure and reducing the design and manufacturing difficulty of the dichroic mirrors.
Benefits of technology
It simplifies the design and manufacture of optical systems, reduces costs, and improves system performance and manufacturability.
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Smart Images
Figure CN116333871B_ABST
Abstract
A kind of fluorescence imaging system, fluorescence imaging direction and gene sequencer, fluorescence imaging system includes light source, first dichroic mirror, second dichroic mirror, third dichroic mirror, first light detector and second light detector, first dichroic mirror is used to transmit first laser and reflect second laser, and for transmitting first fluorescence and reflecting second fluorescence.Due to the first laser and second laser are divided into two laser for excitation, the fluorescence generated by the first laser and second laser excitation can also be collected in two ways, four light paths can be combined and split, can adopt one or more single-pass single-reflection dichroic mirror combination to form excitation light path and imaging light path, the film layer in single-pass single-reflection dichroic mirror only needs to be set as two structures, so that the structure of single-pass single-reflection dichroic mirror is relatively simple, easy to generate manufacturing, can reduce the cost of imaging system, and using single-pass single-reflection dichroic mirror can also simplify light path.
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