Imaging assemblies, devices, and methods
By employing adjustable detection components and image acquisition units in the imaging system, the problem of existing systems being unable to adapt to different breast sizes has been solved, achieving comprehensive high-precision imaging of the breast and detection of small lesions.
Patent Information
- Application Number
- CN202310311055.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-03-27
- Publication Date
- 2026-02-03
- Estimated Expiration
- 2043-03-27
AI Technical Summary
Existing imaging systems, due to their fixed ring structure, cannot adapt to breasts of different sizes, resulting in low imaging flexibility and difficulty in detecting breast lesions smaller than 1 cm.
At least three detection components are used, each of which includes several detection units. The detection units move radially or in opposite directions/away from each other to form a circumferential distribution of different diameters. The image information acquisition unit acquires real-time imaging depth information from all directions. Combined with the drive unit and clock module, the detection field of view is adjusted and the image is reconstructed.
It achieves high-precision imaging of the breast from all angles, improves image reconstruction quality, ensures the accuracy and flexibility of detection data, adapts to breasts of different sizes, and enhances the ability to detect small lesions.
Smart Images

Figure CN116369963B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the field of imaging technology, in particular to an imaging assembly, device and method. BACKGROUND
[0002] At present, breast cancer has become a high-incidence cancer among Chinese women, and early and accurate diagnosis of breast cancer is the key to the treatment of breast cancer. The Breast International Group (BIG) pointed out in the article of "New England Journal of Medicine" that if the treatment is carried out in the 0 stage of breast cancer, the five-year survival rate is close to 100%, but if the treatment is carried out in the four stages of breast cancer, the five-year survival rate will be less than 20%. If the occurrence and development of tumors can be detected before obvious morphological structural changes, it is of great significance for the diagnosis of breast cancer, and functional / molecular imaging is an important imaging means that can achieve this vision. The clinical application value of this type of imaging system is attracting more and more attention.
[0003] If the occurrence and development of tumors can be detected before obvious morphological structural changes, it is of great significance for the diagnosis of breast cancer, and functional / molecular imaging is an important imaging means that can achieve this vision. Because the spatial resolution of the current imaging system is low, it limits its detection ability for breast lesions smaller than 1cm.
[0004] In the process of implementing the present application, the inventors found that the imaging system of the prone hanging imaging currently adopted at least has the following problems:
[0005] The imaging system of the prior art is all of fixed ring structure, and its defects are as follows: because the system is fixed, the imaging structure is the same for different sizes of breast, and it cannot be specifically adjusted, and the flexibility is not high.
[0006] The content described in the background technology is only for the convenience of understanding the related technology in the art, and is not regarded as the recognition of the prior art. SUMMARY
[0007] Therefore, the present application intends to provide an imaging assembly, device and method, which can solve at least one problem in the prior art.
[0008] According to a first aspect of the present application, an imaging assembly is provided, comprising: at least three detection assemblies, each of the detection assemblies comprising a plurality of detection units, detection surfaces of the detection units being distributed along a first circumference, and at least three openings being formed on the first circumference; and an image information acquisition unit arranged on at least one of the detection assemblies; wherein the detection units are movable in a radial direction towards or away from each other, and the detection surfaces of the detection units are movable to be distributed along a second circumference during detection, the first circumference and the second circumference having different diameters; the at least three detection assemblies are rotatable along the second circumference during detection, and at least two of the detection surfaces of the detection units are oppositely arranged and located in a diameter direction of the second circumference during rotation, so as to obtain a full-range pulse signal of a breast; and the image information acquisition unit is rotatable along the second circumference together with the detection assemblies during rotation, so as to acquire full-range real-time imaging depth information, and the full-range real-time imaging depth information is used to obtain an actual spatial position of a response line.
[0009] According to an embodiment of the present application, the imaging assembly further comprises a driving unit configured to drive the detection units to be movable in the radial direction towards or away from each other, and to drive the at least three detection assemblies to be rotatable along the second circumference during detection.
[0010] According to an embodiment of the present application, the driving unit comprises a radial driving unit and a rotating driving unit, the radial driving unit is configured to drive the detection units to be movable in the radial direction towards or away from each other, and the rotating driving unit is configured to drive the at least three detection assemblies to be rotatable along the second circumference during detection.
[0011] According to an embodiment of the present application, the number of the detection assemblies is three.
[0012] According to an embodiment of the present application, the detection units are movable in the radial direction towards or away from each other based on the full-range real-time imaging depth information acquired by the image information acquisition unit.
[0013] According to an embodiment of the present application, when each of the detection assemblies is rotatable along the second circumference during detection, an angle of rotation per unit time of each of the detection assemblies is not completely same.
[0014] According to an embodiment of the present application, when each of the detection assemblies is rotatable along the second circumference during detection, an angle of rotation per unit time of each of the detection assemblies is same.
[0015] According to an embodiment of the present application, the detection units comprise at least one PET detector, and each of the PET detectors comprises a scintillation crystal, a photoelectric conversion device and an electronic device.
[0016] According to one embodiment of the present application, further comprising: a clock module, so that the at least three detection components are clocked synchronously with the image information acquisition unit.
[0017] According to one embodiment of the present application, the real-time imaging depth information further comprises image frames and time information corresponding to the image frames.
[0018] According to one embodiment of the present application, the image information acquisition unit comprises a CMOS image sensor, an image acquisition module, a dynamic storage module, and an output control module, the CMOS image sensor is used to capture image information, the image acquisition module is used to acquire images and corresponding time based on the image information, and the output control module is used to output the time and image frames.
[0019] According to one embodiment of the present application, the image information acquisition unit is a 3D TOF depth camera.
[0020] According to a second aspect of the present application, an imaging device is provided, comprising: the imaging assembly according to the embodiments of the present application; a sampling module, which acquires sampling data based on pulse signals acquired by the detection components; a response line acquisition module, which acquires energy information and time information of the pulse signals based on the sampling data, and acquires coincidence events according to the energy information and the time information, the middle connecting line of the scintillation crystals of the two detection units that detect the coincidence events is a response line, and the corresponding scintillation crystal numbers at both ends of each acquired response line are recorded; a matching module, which acquires actual positions of each scintillation crystal at different time points based on the all-around real-time imaging depth information acquired by the image information acquisition unit, matches the actual positions of the scintillation crystals corresponding to each response line at different time points under a synchronous clock, and acquires actual spatial positions of the response lines; a response line correction module, which corrects the response lines based on the actual spatial positions of the response lines; and an image reconstruction module, which reconstructs images based on the corrected response lines.
[0021] According to one embodiment of the present application, the sampling module comprises an ADC sampling module or an MVT sampling module.
[0022] According to one embodiment of the present application, further comprising a shaping module, which is used to shape the pulse signals.
[0023] According to one embodiment of the present application, the shaping module comprises a filter amplification circuit and a shaping circuit.
[0024] According to one embodiment of the present application, further comprising a control module, the control module comprising: a position instruction module, which is used to send driving instructions of the driving unit, so that each detection unit is in a suitable position to adjust the size of the detection field of view; and a time synchronization module, which uses a synchronous clock to synchronize the working time of the imaging device.
[0025] According to a third aspect of the present application, an imaging method is provided, which uses the imaging device described in the embodiments of the present application to image, comprising: S1, driving the detection units of the at least three detection assemblies to move radially towards or away from each other, so that when the detection surfaces of the detection units are distributed along the second circumference, the detection field is adapted to the breast; S2, the main control board sends a collection start signal and collection total time information, the driving part drives the detection units of the at least three detection assemblies to rotate to obtain a pulse signal, and the image information collection part rotates along the second circumference to follow the detection assemblies to collect full-range real-time imaging depth information; S3, based on the pulse signal, the response lines and the scintillation crystals corresponding to each response line are obtained, based on the real-time imaging depth information, the actual positions of each scintillation crystal at different time points are obtained, the actual positions of the scintillation crystals corresponding to each response line at different time points are matched under a synchronous clock, and the actual spatial positions of the response lines are obtained; S4, based on the actual spatial positions of the response lines, the response lines are corrected; and S5, an image reconstruction module reconstructs an image based on the corrected response lines.
[0026] According to an embodiment of the present application, the S1 comprises: S11, based on the pre-positioning signal sent by the main control board, a detection field adapted to the breast is preliminarily obtained; and S12, based on the full-range real-time imaging depth information collected by the image information collection part following the rotation of the detection assemblies along the second circumference, a 3D model of the breast is obtained, and the driving part drives the detection units to move radially to adjust to the detection field adapted to the breast according to the 3D model of the breast.
[0027] According to an embodiment of the present application, the S11 comprises: the driving part drives the detection units of the at least three detection assemblies to move radially towards or away from each other, so that when the detection surfaces of the detection units are distributed along the second circumference, the detection field is adapted to the breast.
[0028] In the embodiments of the present application, the detection assemblies move radially towards or away from each other, so that when the detection surfaces of the detection units are distributed along the second circumference, the detection field is adapted to the breast. Specifically, the detection assemblies move radially towards or away from each other under the driving of the driving part. In an example, the driving direction and distance of the detection assemblies driven by the driver are determined by the control module, the control module sends the direction and distance that each detection assembly needs to translate to the driver based on the full-range real-time imaging depth information collected by the image information collection part, guides the movement direction and movement distance of the detection units, helps to obtain the best detection field, ensures the accuracy of the detection data, and helps to improve the image reconstruction quality.
[0029] Some optional features and other effects of the embodiments of the present application are described below, and some can be understood by reading the present text. BRIEF DESCRIPTION OF DRAWINGS
[0030] The accompanying drawings are used to assist in the detailed description of the embodiments of this application. The elements shown in the drawings are not limited to the scale shown in the drawings, and the same or similar reference numerals in the drawings represent the same or similar elements, wherein:
[0031] Figure 1 This is a three-dimensional structural schematic diagram of the imaging component according to an embodiment of this application;
[0032] Figure 2 This is a three-dimensional structural diagram of a probe bed according to an embodiment of this application. Detailed Implementation
[0033] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to specific embodiments and accompanying drawings. Here, the illustrative embodiments and descriptions of this invention are used to explain the invention, but are not intended to limit the invention.
[0034] The term "comprising" and its variations as used herein signify open inclusion, i.e., "including but not limited to". Unless otherwise stated, the term "or" means "and / or". The term "based on" means "at least partially based on". The terms "one example embodiment" and "one embodiment" mean "at least one example embodiment". The term "another embodiment" means "at least one additional embodiment". The terms "first", "second", etc., may refer to different or the same objects. Other explicit and implicit definitions may also be included below.
[0035] The specific embodiments of this application will now be described in detail with reference to the accompanying drawings.
[0036] Figure 1 The structure of an imaging component according to an embodiment of this application is shown. For example... Figure 1As shown, the imaging component 1000 includes: at least three detection components 100, each detection component 100 including a plurality of detection units 110, the detection surfaces of the detection units 110 being distributed along a first circumference, the first circumference having at least three openings 111; and an image information acquisition unit 200 disposed on at least one detection component 100; wherein, the detection units 110 can move radially towards or away from each other, and the detection surfaces of the detection units 110 change their movement during detection to be distributed along a second circumference, the diameters of the first circumference and the second circumference being different; the at least three detection components 100 rotate along the second circumference during detection, and during the rotation, the detection surfaces of at least two of the detection units 110 are arranged opposite each other and located in the diameter direction of the circumference to acquire omnidirectional pulse signals of the breast; the image information acquisition unit 200 follows the detection components 100 to rotate along the second circumference, acquiring omnidirectional real-time imaging depth information, the omnidirectional real-time imaging depth information being used to obtain the actual spatial position of the response line.
[0037] Those skilled in the art should understand that, since the detection surface is typically planar, "the detection surface is distributed along the first circumference" means that each edge of the polygon formed by connecting the detection surfaces is tangent to the same circumference, or the midpoint of each detection surface lies on the same circumference. "The detection surface changes its distribution along the second circumference during detection" means that when the detection assembly 100 rotates during detection, each edge of the polygon formed by connecting the detection surfaces of the detection units 110 is tangent to the same circumference, or the midpoint of each detection surface lies on the same circumference. If the manufacturing cost of the detection surface is not considered, it can also be made into an arc-shaped plane; this is readily apparent to those skilled in the art and will not be elaborated upon here.
[0038] In the imaging component of this application, the detection unit 110 can move radially towards or away from each other, so that the detection surface of the detection module detection unit 110 changes its movement during detection to be distributed along a second circumference. The second circumference is different from the first circumference where the detection surface was located before detection, thereby forming a detection field of view adapted to the breast of the object to be detected, ensuring accurate detection data and helping to improve image reconstruction quality. In addition, the omnidirectional real-time imaging depth information collected by the image information acquisition unit can be used to guide the movement direction and movement distance of the detection unit 110, which helps to obtain the optimal detection field of view. Furthermore, based on the omnidirectional real-time imaging depth information collected by the image information acquisition unit, the actual spatial position of the scintillation crystal pair corresponding to the response line acquired at different times can be obtained, which helps to obtain the actual spatial position of the response line acquired at different times, thereby correcting the response line and improving image reconstruction quality.
[0039] See Figure 1The embodiments of this application include three detection components 100. All three detection components 100 are arc-shaped and located on the same circumference. The three detection components 100 are arranged at intervals. In a preferred example, the three detection components 100 are arranged at equal intervals, that is, the interval between two adjacent detection components 100 is 60 degrees.
[0040] In this embodiment of the application, each detection component 100 includes multiple detection units 110, and the center of the detection surface of each detection unit 110 is located on the circumference of the detection component 100.
[0041] In one embodiment of this application, each detection unit 110 includes at least one PET detector. The PET detector includes a scintillation crystal, a photoelectric conversion device, and electronic devices coupled together. The scintillation crystal includes, but is not limited to, lutetium silicate, and the photoelectric conversion device includes, but is not limited to, a silicon photomultiplier (SiPM). The scintillation crystal converts gamma rays into visible light, and the photoelectric conversion device converts the visible light into a pulse signal. In this embodiment, the scintillation crystals are pre-numbered to facilitate subsequent acquisition of the scintillation crystals corresponding to both ends of the response line. For example, Figure 1 The imaging assembly shown includes a total of 3 detection assemblies 100, each detection assembly includes 3 detection units 110, and each detection unit includes one PET detector, that is, there are a total of 9 PET detectors. The corresponding 9 scintillation crystals are numbered 1-9. If the scintillation crystals at both ends of a certain response line obtained based on the pulse signal output by the detection assembly 100 are 1 and 6 respectively, then the response line can be recorded as LOR1-6.
[0042] In the embodiments of this application, the pulse signal output by the photoelectric conversion device (such as SiPM) should be understood as any pulse signal capable of sampling. Its essence is a physical quantity that undergoes a sudden change within a short time and then rapidly returns to its initial value; this physical quantity has certain characteristics. In this application, the pulse signal particularly includes scintillation pulses, and several embodiments will be described herein using scintillation pulses as examples. In these embodiments, pulse signals and scintillation pulses can be interchanged. For example, in some embodiments, the scintillation pulse typically has a rising edge and a falling edge, and these rising and falling edges can be represented by a function model. In some embodiments, the pulse signal is a scintillation pulse signal. For example, the scintillation pulse corresponding to a gamma photon typically exhibits a relatively fast rising edge and a relatively slow falling edge; the rising edge can be characterized by a linear function, and the falling edge can be characterized by an exponential function.
[0043] In this embodiment, the pulse signal can be in the form of an electrical pulse signal, an acoustic pulse signal, a thermal pulse signal, or a pressure wave signal, etc. For example, when the pulse signal is an electrical pulse signal, its corresponding characteristics can be the voltage or current of the electrical pulse signal; when the pulse signal is an acoustic pulse signal, its corresponding characteristic can be the sound intensity of the acoustic pulse signal, and so on, which will not be elaborated further here. Correspondingly, the threshold can have various forms. For example, when the pulse signal is an electrical pulse signal, its corresponding threshold can be a voltage threshold, a current threshold, or an energy threshold; when the pulse signal is an acoustic pulse signal, its corresponding threshold can be a sound intensity threshold, and so on, which will not be elaborated further here.
[0044] Those skilled in the art should understand that the pulse signal in this application can be extended to a continuous signal. Generally, it is sufficient to regard the continuous signal as a pulse signal arranged according to a certain period. The pulse signal in this application is not intended to limit the sampled signal.
[0045] In one embodiment, the imaging assembly 1000 further includes a driving unit that drives the detection units 110 to move radially toward or away from each other, and drives at least three of the detection components to rotate along the second circumference during detection. In one example, the driving unit includes a radial driving unit 300 and a rotation driving unit (not shown in the figure). The radial driving unit 300 corresponds one-to-one with the detection components 100. The radial driving unit 300 drives the detection units 110 to move radially toward or away from each other, and the rotation driving unit drives at least three detection components 100 to rotate along the second circumference during detection. In a specific example of this application, when the detection components 100 rotate along the second circumference during detection, the rotation angle of each detection component per unit time is not exactly the same. Preferably, when the detection components 100 rotate along the second circumference during detection, the rotation angle of each detection component 100 per unit time is the same. In some embodiments, the rotation angle of each detection component 100 per unit time may also be different, depending on the specific needs.
[0046] In this embodiment, when the radial drive unit 300 drives the detection unit 110 to move radially towards each other, the diameter of the circumference where the detection surface of each detection unit 110 is located decreases; when the radial drive unit 300 drives the detection unit 110 to move radially away from each other, the diameter of the circumference where the detection surface of each detection unit 110 is located increases. By driving the detection unit to move radially towards or away from each other, the detection field of view can be adjusted to match the breast of the object to be detected, and the best detection field of view can be obtained to ensure accurate detection data and help improve the quality of subsequent image reconstruction.
[0047] In some embodiments, the imaging component 1000 further includes a clock module, which synchronizes at least three detection components 100 with the clock of the image information acquisition unit 200, i.e., both operate under the same clock.
[0048] In one embodiment, the real-time imaging depth information also includes image frames and the corresponding time information of the image frames.
[0049] In some embodiments, the image information acquisition unit includes a CMOS image sensor, an image acquisition module, a dynamic storage module, and an output control module. The CMOS image sensor is used to capture image information, the image acquisition module is used to acquire images and their corresponding times based on the image information, and the output control module is used to output the time and image frames. In a specific example, the image information acquisition unit is a 3D TOF depth camera.
[0050] In one embodiment of this application, Figure 2 A detection bed is shown, having a bed board 400, on which a breast detection hole 410 is formed. This application... Figure 1 In this embodiment, the imaging component 1000 is mounted on the bed board 400 of the detection bed, and three detection components 100 are spaced apart around the breast detection hole 410. In one example of this application, the three detection components 100 are mounted on a circular turntable 500, which is fixedly mounted on the bed board 400. The circular turntable 500 has holes corresponding to the breast detection hole 410, and the three detection components 100 are spaced apart around the holes. The circular turntable 500 is driven to rotate by a rotation drive unit, which in turn drives the three detection components 100 to rotate.
[0051] In this embodiment, the detection components 100 move radially towards or away from each other based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit. This ensures that when the detection surfaces of the detection units are distributed along the second circumference, they have a detection field of view adapted to the breast. Specifically, the detection components 100 move radially towards or away from each other under the drive of the drive unit. In one example, the translation direction and distance of the driver-driven detection components 100 are determined by the control module. Based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, the control module sends the direction and distance of translation required for each detection component 100 to the driver, guiding the movement direction and distance of the detection units 110. This helps to obtain the optimal detection field of view, ensures accurate detection data, and helps improve image reconstruction quality.
[0052] This application provides an imaging device in several embodiments. The imaging device includes: an imaging component 1000 as described in this application embodiment, a sampling module, a response line acquisition module, a matching module, a response line correction module, and an image reconstruction module; the sampling module acquires sampling data based on pulse signals acquired by the detection component; the response line acquisition module acquires energy and time information of the pulse signals based on the sampling data, filters and acquires matching events based on the energy and time information, and uses the midline connecting the surfaces of the scintillation crystals of the two detection units that detect matching events as the response line, recording the scintillation crystal numbers corresponding to both ends of each acquired response line; the matching module acquires the actual positions of each scintillation crystal at different times based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, matches the actual positions of the scintillation crystals corresponding to each response line at different times under a synchronous clock, and acquires the actual spatial position of the response line; the response line correction module corrects the response lines based on their actual spatial positions; and the image reconstruction module reconstructs an image based on the corrected response lines.
[0053] In some embodiments, after the PET detector of the detection unit 110 outputs a pulse signal, a sampling module can be used to sample the pulse signal and obtain sampled data. The sampling module can be an ADC sampling module or an MVT sampling module. The specific use of an ADC sampling module or an MVT sampling module to sample the pulse signal and obtain sampled data is detailed in existing technology and is not the core of this application; therefore, it will not be elaborated further here.
[0054] In one embodiment, the response line acquisition module includes a pulse fitting and restoration module and a coincidence module. The pulse fitting and restoration module is used to reconstruct the pulse waveform based on the sampled data and integrate to obtain the energy information of the pulse signal. The response line acquisition module can also obtain the time information of the pulse signal based on the sampled data.
[0055] The coincidence module has a preset time window and energy window, which are used to filter and obtain coincidence events based on the energy and time information of the pulse signal, and obtain the response line based on the coincidence events. Both the time window and energy window are set according to prior information.
[0056] In this embodiment, the matching module can acquire image frames and their corresponding times based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, thereby acquiring the actual positions of each scintillation crystal at different times; when at least three detection components 100 rotate along the second circumference during detection, the response line acquisition module acquires the response line based on the pulse signal output by the detection component 100, and the number of the scintillation crystal pair corresponding to the response line acquired at different times is also transmitted to the matching module.
[0057] After receiving the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, the detection time of each response line acquired by the response line acquisition module, and the numbering information of the scintillation crystal pair corresponding to each response line, the matching module searches for the actual position of the scintillation crystal pair acquired by the image information acquisition unit at that time based on the detection time of each response line and the numbering information of the scintillation crystal pair corresponding to each response line. In other words, it obtains the actual spatial position of the response line and realizes the matching of the actual position of the scintillation crystal corresponding to each response line at different times under the synchronization clock. For example, in one instance, assuming that the three detection components 100 rotate at the same angle per unit time, and that it takes 10 ns for each of the three detection components 100 to complete one revolution around the second circumference, the number and position of each scintillation crystal are recorded at the initial time (0 ns). During the process of the three detection components 100 rotating to detect the breast, three response lines are detected: LOR1-6 at the 2nd ns, LOR3-8 at the 5th ns, and LOR1-6 at the 8th ns. The image information acquisition unit collects the omnidirectional real-time imaging depth information as image frames and their corresponding times, and obtains the angle between the line connecting scintillation crystals 1 and 6 at the 2nd ns and the line connecting 1 and 6 at the initial time (0 ns). Obtain the angle between the line connecting scintillation crystals 3 and 8 at the 5th ns mark and the line connecting crystals 3 and 8 at the initial time (0 ns). The angle between the line connecting scintillation crystals 1 and 6 at the 8th ns mark and the line connecting 1 and 6 at the initial time (0 ns). This achieves the matching of the detected response line with its actual spatial position. In this embodiment, based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, the actual spatial position of the scintillation crystal pair corresponding to the response line acquired at different times can be obtained. This helps to obtain the actual spatial position of the response line acquired at different times, thereby correcting the response line and improving the image reconstruction quality.
[0058] In one embodiment, after obtaining the actual spatial position of the response line based on the matching module, a response line correction module can be used to correct the response line. The response line correction module corrects the response line obtained by the response line acquisition module to the actual spatial position of the response line obtained by the matching module, so as to perform image reconstruction based on the accurate response line and improve the image reconstruction quality.
[0059] In one embodiment, the image reconstruction module reconstructs the image based on the corrected response line. For details, please refer to the prior art, which is not the core of this application and will not be described in detail here.
[0060] In one embodiment, the imaging device further includes a shaping module for processing the pulse signal. In one example, the shaping module includes a filter amplification circuit and a shaping circuit. The specific design of the shaping module can be found in existing technology and is not the core of this application; therefore, it will not be described in detail here.
[0061] In one example, the imaging system further includes a control module, which includes: a position command module for sending drive commands to each drive unit to position each detection unit in a suitable position to adjust the size of the detection field of view; and a time synchronization module that uses a synchronous clock to synchronize the working time of the imaging device. In this example, a unified synchronous clock module is used as the time synchronization module. Based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, the driver drives the detection components 100 to move radially towards or away from each other, so that when the detection surfaces of the detection modules are distributed along the second circumference, they have a detection field of view adapted to the breast. In one example, the translation direction and distance of the driver-driven detection components 100 are determined by the control module. Based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, the control module sends the direction and distance that each detection component 100 needs to translate to to the driver, so that each detection component 100 moves under the intensity of the translation driver 300 until the detection surface of each detection unit 110 is located on the second circumference, forming the optimal detection field of view for detecting the breast of the object to be detected, so that the subsequent rotation drive unit drives each detection component to rotate and detect the breast.
[0062] Some embodiments of this application provide an imaging method, which uses the imaging device described in the embodiments of this application to perform imaging. The imaging method includes:
[0063] S1. Drive the detection units of the at least three detection components to move radially toward each other or apart, so that when the detection surfaces of the detection units are distributed along the second circumference, they have a detection field of view adapted to the breast.
[0064] In one embodiment, S1 includes:
[0065] S11. Based on the pre-positioning signal of the drive command issued by the control module, a detection field of view adapted to the breast is initially obtained.
[0066] In some embodiments, S11 includes:
[0067] Based on a pre-positioning signal, the driving unit drives the detection units of the at least three detection components to move radially toward or away from each other, so that when the detection surfaces of the detection units are distributed along the second circumference, they have a detection field of view adapted to the breast.
[0068] S12. Based on the image information acquisition unit following the detection component to rotate along the second circumference, the real-time imaging depth information of the entire circumference is acquired to obtain a 3D model of the breast. According to the 3D model of the breast, the driving unit drives the detection unit to move radially and adjust it to a detection field of view that is compatible with the breast.
[0069] S2. The main control board sends a start signal for data acquisition and information on the total acquisition duration. The drive unit drives the detection units of the at least three detection components to rotate and acquire pulse signals. The image information acquisition unit follows the detection components and rotates along the second circumference to acquire real-time imaging depth information from all directions.
[0070] S3. Based on the pulse signal, obtain the response line and the scintillation crystal corresponding to each response line. Based on the real-time imaging depth information, obtain the actual position of each scintillation crystal at different times. Match the actual position of each scintillation crystal corresponding to each response line at different times under the synchronous clock to obtain the actual spatial position of the response line.
[0071] S4. Correct the response line based on its actual spatial location.
[0072] Based on the actual spatial position of the scintillation crystal at different times obtained in step S3, the response line is corrected to obtain the actual spatial position of the response line.
[0073] S5, the image reconstruction module reconstructs the image based on the corrected response lines.
[0074] For specific details on image reconstruction, please refer to existing technologies. This is not the core of this application and will not be elaborated upon here.
[0075] This document describes several embodiments, but for the sake of brevity, the descriptions of the embodiments are not exhaustive, and identical or similar features or parts between the embodiments may be omitted. In this document, "one embodiment," "some embodiments," "example," "specific example," or "some examples" refers to at least one embodiment or example applicable to this application, but not all embodiments. The above terms do not necessarily mean referring to the same embodiment or example. Without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of the different embodiments or examples.
[0076] The exemplary systems and methods of this application have been specifically shown and described with reference to the above embodiments, which are merely examples of the best mode for implementing the systems and methods. Those skilled in the art will understand that various changes can be made to the embodiments of the systems and methods described herein without departing from the spirit and scope of the invention as defined in the appended claims when implementing the systems and / or methods.
Claims
1. An imaging component, characterized in that, include: At least three detection components, each comprising a plurality of detection units, wherein the detection surfaces of the detection units are distributed along a first circumference, and at least three openings are formed on the first circumference; An image information acquisition unit is mounted on at least one detection component; The detection units can move radially towards or away from each other. The detection surfaces of the detection units change their movement during detection to be distributed along a second circumference. The diameters of the first circumference and the second circumference are different. The at least three detection components rotate along the second circumference during detection. During the rotation, the detection surfaces of at least two of the detection units are arranged opposite each other and located in the diametrical direction of the circumference to obtain pulse signals from all directions of the breast. The image information acquisition unit follows the detection component and rotates along the second circumference to acquire real-time imaging depth information from all directions. The real-time imaging depth information from all directions is used to guide the movement direction and distance of the detection unit, and to obtain the actual spatial position of the response line and to correct the response line.
2. The imaging component according to claim 1, characterized in that, Also includes: The driving unit drives the detection unit to move radially toward or away from each other, and drives the at least three detection components to rotate along the second circumference during detection.
3. The imaging component according to claim 2, characterized in that, The driving unit includes a radial driving unit and a rotary driving unit. The radial driving unit drives the detection unit to move radially toward or away from each other, and the rotary driving unit drives the at least three detection components to rotate along the second circumference during detection.
4. The imaging component according to claim 1, characterized in that, The number of detection components is three.
5. The imaging component according to any one of claims 1-4, characterized in that, The detection unit moves radially towards or away from the image information acquisition unit based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit.
6. The imaging component according to claim 1, characterized in that, When the detection components rotate along the second circumference during detection, the angle of rotation of each detection component per unit time is not exactly the same.
7. The imaging component according to claim 1, characterized in that, When the detection components rotate along the second circumference during detection, the angle of rotation of each detection component is the same per unit time.
8. The imaging assembly according to claim 1, characterized in that, The detection unit includes at least one PET detector, which includes a scintillation crystal, a photoelectric conversion device, and electronic devices coupled to each other.
9. The imaging component according to claim 1, characterized in that, Also includes: A clock module enables at least three detection components to synchronize with the clock of the image information acquisition unit.
10. The imaging assembly according to claim 1, characterized in that, The real-time imaging depth information also includes image frames and the corresponding time information of the image frames.
11. The imaging assembly according to claim 10, characterized in that, The image information acquisition unit includes a CMOS image sensor, an image acquisition module, a dynamic storage module, and an output control module. The CMOS image sensor is used to capture image information, the image acquisition module is used to acquire images and their corresponding times based on the image information, and the output control module is used to output the time and image frames.
12. The imaging component according to claim 1, characterized in that, The image information acquisition unit is a 3D TOF depth camera.
13. An imaging device, characterized in that, include: The imaging component according to any one of claims 1-12; The sampling module acquires sampling data based on the pulse signal obtained by the detection component; The response line acquisition module acquires the energy and time information of the pulse signal based on the sampled data, filters and acquires matching events based on the energy and time information, and the middle line connecting the scintillation crystal surfaces of the two detection units that detect matching events is the response line. The scintillation crystal numbers corresponding to the two ends of each acquired response line are recorded. The matching module, based on the omnidirectional real-time imaging depth information acquired by the image information acquisition unit, obtains the actual position of each scintillation crystal at different times, matches the actual position of each scintillation crystal corresponding to each response line at different times under the synchronous clock, and obtains the actual spatial position of the response line. The response line correction module corrects the response line based on its actual spatial position. The image reconstruction module reconstructs the image based on the corrected response lines.
14. The imaging apparatus according to claim 13, characterized in that, The sampling module includes an ADC sampling module or an MVT sampling module.
15. The imaging apparatus according to claim 13, characterized in that, It also includes a shaping module for processing pulse signals.
16. The imaging apparatus according to claim 15, characterized in that, The shaping module includes a filter amplifier circuit and a shaping circuit.
17. The imaging apparatus according to claim 13, characterized in that, It also includes a control module, which includes: a position command module, used to send drive commands to the drive unit so that each detection unit is in a suitable position to adjust the size of the detection field of view; and a time synchronization module, which uses a synchronous clock to synchronize the working time of the imaging device.
18. An imaging method, characterized in that, Imaging using the imaging apparatus according to any one of claims 13-17, comprising: S1. Drive the detection units of the at least three detection components to move radially toward each other or apart, so that when the detection surfaces of the detection units are distributed along the second circumference, they have a detection field of view adapted to the breast. S2. The main control board sends a data acquisition start signal and data acquisition total duration information. The detection units of the at least three detection components rotate to acquire pulse signals. The image information acquisition unit follows the detection components and rotates along the second circumference to acquire real-time imaging depth information from all directions. S3. Based on the pulse signal, obtain the response line and the scintillation crystal corresponding to each response line. Based on the real-time imaging depth information, obtain the actual position of each scintillation crystal at different times. Match the actual position of each scintillation crystal corresponding to each response line at different times under the synchronous clock to obtain the actual spatial position of the response line. S4. Correct the response line based on its actual spatial location; S5, the image reconstruction module reconstructs the image based on the corrected response lines.
19. The imaging method according to claim 18, characterized in that, S1 includes: S11. Based on the prepositioning signal emitted by the main control board, a preliminary detection field of view adapted to the breast is obtained; S12. Based on the image information acquisition unit following the detection component to rotate along the second circumference, the real-time imaging depth information of the entire circumference is acquired to obtain a 3D model of the breast. According to the 3D model of the breast, the driving unit drives the detection unit to move radially and adjust it to a detection field of view that is compatible with the breast.
20. The imaging method according to claim 19, characterized in that, S11 includes: The driving unit drives the detection units of the at least three detection components to move radially toward or away from each other based on a pre-positioning signal, so that when the detection surfaces of the detection units are distributed along the second circumference, they have a detection field of view adapted to the breast.
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