Parathyroid gland identification and blood supply detection device and detection method based on spectrometer

Abstract

Embodiments of the present invention disclose a spectrometer-based parathyroid gland identification and blood supply detection device and method. The device comprises an incident optical path, a receiving optical path, and an optical path analysis module. The incident optical path includes a near-infrared light source, a red light source, and an incident optical fiber. The receiving optical path includes a receiving optical fiber, an electrically controlled optical shutter, and a reflected light optical fiber. The optical path analysis module includes a spectrometer and a main control circuit board. The reflected light optical fiber directs light passing through the electrically controlled optical shutter and the receiving optical fiber into the spectrometer. The main control circuit board connects the spectrometer, the electrically controlled optical shutter, the near-infrared light source, and the red light source. The incident optical fiber guides the near-infrared light and red light to a detection target. The receiving optical fiber receives the target's autofluorescence and reflected light. The present invention enables simultaneous parathyroid gland identification and blood supply detection using a single device. It has a simple structure, relatively low cost, and is easily applicable.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a parathyroid gland identification and blood supply detection device and a detection method based on a spectrometer. Background Art

[0002] The parathyroid glands are important endocrine glands in the human body. Located above and below the thyroid gland, they mainly secrete parathyroid hormone, which regulates the metabolism of calcium and phosphorus in the human body and plays a very critical role. The parathyroid glands are relatively small, and it is generally believed that there are 4 or 8 parathyroid glands above and below the thyroid gland. Their position is not fixed, especially the anatomical structure often changes. Sometimes the parathyroid glands may be accidentally damaged during thyroid surgery, but if the parathyroid glands are reburied in the tissue, they can still survive and continue to secrete parathyroid hormone, calcitonin, etc., to maintain normal calcium and phosphorus metabolism in the blood and regulate bone mass. If there is a problem with the parathyroid glands, there will be fluctuations in calcium and phosphorus, and severe osteoporosis and even fractures may occur. If hypercalcemia occurs, it is also a very urgent and critical situation. Protection of the parathyroid glands during thyroid surgery is an important indicator for evaluating the quality of thyroid surgery. In traditional radical thyroidectomy, the identification of the parathyroid glands and the judgment of their blood supply indicators, including blood oxygen and pulse information, mainly rely on the doctor's clinical surgical experience, making it difficult to unify the surgical efficacy. Therefore, the use of medical technology to assist in the identification of the parathyroid glands and the detection of their blood supply data indicators is of great clinical significance.

[0003] Optical detection technology allows for non-invasive intraoperative identification of parathyroid glands and monitoring of their blood supply. When stimulated by an excitation light source, the parathyroid glands produce autofluorescence with a peak near 820nm, clearly distinguishing them from the surrounding thyroid gland, lymph nodes, and fat. This characteristic allows for optical identification of the parathyroid glands. By exploiting the differences in the absorption spectra of different blood components, photoplethysmography (PEP) can be used to measure blood oxygenation, pulse rate, and other blood supply parameters. Currently, most parathyroid testing products on the market offer a single function and lack the ability to simultaneously identify and monitor the parathyroid glands and their blood supply. Summary of the Invention

[0004] The object of the present invention is to provide a parathyroid gland identification and blood supply detection device and method based on a spectrometer, which is used to solve at least one of the above-mentioned technical problems. The device has the ability to simultaneously perform parathyroid gland identification and blood supply detection in one device, has a simple structure, is relatively low in cost, and is easy to promote and use.

[0005] The embodiment of the present invention is achieved as follows:

[0006] A parathyroid gland identification and blood supply detection device based on a spectrometer includes an incident light path, a receiving light path and an optical path analysis module. The incident light path emits light toward a detection target object 7, the receiving light path receives the autofluorescence and reflected light of the detection target object 7, and the optical path analysis module is connected to the incident light path and the receiving light path respectively.

[0007] The incident light path includes a near-infrared light source 1, a red light source 4 and an incident optical fiber 6. The light paths emitted by the infrared light source 1 and the red light source 4 are respectively coupled into the incident optical fiber 6.

[0008] The receiving optical path includes a receiving optical fiber 8 , an electrically controlled optical shutter 11 and a reflected light optical fiber 13 . The reflected light optical fiber 13 receives the autofluorescence and reflected light of the detection target 7 .

[0009] The optical path analysis module includes a spectrometer 12 and a main control circuit board 14. The reflected light optical fiber 13 guides the light passing through the electrically controlled optical shutter 11 and the receiving optical fiber 8 into the spectrometer 12. The main control circuit board 14 connects the spectrometer 12, the electrically controlled optical shutter 11, the near-infrared light source 1 and the red light source 4.

[0010] In a preferred embodiment of the present invention, the incident optical fiber 6 of the above-mentioned spectrometer-based parathyroid identification and blood supply detection device guides the near-infrared light emitted by the near-infrared light source 1 and the red light emitted by the red light source 4 to the detection target 7.

[0011] The receiving optical fiber 8 receives the autofluorescence and reflected light of the detection target 7 .

[0012] The technical effect thereof is that it is used to illuminate the detection target object 7 and perform optical recognition by receiving the autofluorescence and reflected light of the detection target object 7.

[0013] In a preferred embodiment of the present invention, the incident light path of the above-mentioned parathyroid gland identification and blood supply detection device based on a spectrometer further includes a near-infrared bandpass filter 3 and a first dichroic mirror 5 .

[0014] The near-infrared bandpass filter 3 is arranged on the light-emitting side of the near-infrared light source 1 .

[0015] The first dichroic mirror 5 is tiltedly disposed on the light-emitting side of the near-infrared light source 1 and the light-emitting side of the red light source 4 .

[0016] The input optical fiber 6 receives the light passing through and reflected by the first dichroic mirror 5 .

[0017] The technical effect is that the bandpass filter only allows light of a specific wavelength band to pass through. The near-infrared bandpass filter 3 allows near-infrared light to pass through.

[0018] A dichroic mirror transmits certain wavelengths of light almost completely, while reflecting other wavelengths of light almost completely.

[0019] In a preferred embodiment of the present invention, a first convex lens 201 is provided between the near-infrared light source 1 and the near-infrared bandpass filter 3 of the parathyroid gland identification and blood supply detection device based on a spectrometer.

[0020] A second convex lens 202 is provided between the red light source 4 and the first dichroic mirror 5 .

[0021] A third convex lens 203 is provided between the first dichroic mirror 5 and the incident optical fiber 6 .

[0022] The technical effect is that a convex lens is provided to achieve collimation or focusing of light.

[0023] In a preferred embodiment of the present invention, the receiving light path of the above-mentioned parathyroid gland identification and blood supply detection device based on a spectrometer further includes a fluorescence bandpass filter 10 and a second dichroic mirror 9 .

[0024] The second dichroic mirror 9 is tilted and arranged on the light-emitting side of the receiving optical fiber 8 .

[0025] The fluorescent bandpass filter 10 is arranged on the light-transmitting side of the second dichroic mirror 9 .

[0026] The electrically controlled optical shutter 11 is disposed on the light reflecting side of the second dichroic mirror 9 .

[0027] The technical effect is that the second dichroic mirror 9 has an initial response wavelength between the parathyroid tissue fluorescence wavelength and the near-infrared light source wavelength, allowing the tissue fluorescence to pass while reflecting near-infrared and red light. The fluorescence bandpass filter 10 is used to pass parathyroid fluorescence while blocking stray light from other wavelengths. The electrically controlled optical shutter 11 is electrically controlled to open and close, allowing light to pass when open and blocking it when closed.

[0028] In a preferred embodiment of the present invention, the reflected light fiber 13 of the above-mentioned parathyroid gland identification and blood supply detection device based on a spectrometer receives the light passing through and reflected from the second dichroic mirror 9 and guides the light into the spectrometer 12 .

[0029] In a preferred embodiment of the present invention, a fourth convex lens 204 is provided between the receiving optical fiber 8 and the second dichroic mirror 9 of the parathyroid gland identification and blood supply detection device based on a spectrometer.

[0030] A fifth convex lens 205 is provided between the electrically controlled optical shutter 11 and the reflecting light optical fiber 13 .

[0031] A sixth convex lens 206 is provided between the fluorescence bandpass filter 10 and the reflected light optical fiber 13 .

[0032] In a preferred embodiment of the present invention, the electrically controlled optical shutter 11 of the above-mentioned spectrometer-based parathyroid gland identification and blood supply detection device is opened, and the light of the receiving optical fiber 8 is reflected by the second dichroic mirror 9 and then connected to the reflected light optical fiber 13.

[0033] The electrically controlled optical shutter 11 is closed, blocking the light reflected by the second dichroic mirror 9 .

[0034] In a preferred embodiment of the present invention, the light of the receiving optical fiber 8 of the above-mentioned spectrometer-based parathyroid gland identification and blood supply detection device passes through the second dichroic mirror 9, passes through the fluorescent bandpass filter 10, and is connected to the reflected light optical fiber 13.

[0035] In a preferred embodiment of the present invention, the optical path analysis module of the above-mentioned spectrometer-based parathyroid identification and blood supply detection device also includes a display terminal 15, which is connected to the main control circuit board 14 to display an operation interface and parathyroid fluorescence, blood oxygen, and pulse data.

[0036] Its technical effect is: through the main control circuit board 14, it drives and controls the opening and closing of the two light sources and modulates their respective luminous intensities, controls the opening and closing of the electric shutter, receives data from the spectrometer and performs calculations and analysis according to a certain algorithm, and outputs information related to fluorescence, blood oxygen, and pulse to the display terminal 15.

[0037] A detection method for the parathyroid gland identification and blood supply detection device based on a spectrometer as described above comprises:

[0038] The detection optical fiber is placed close to the detection target object 7, the main control circuit board 14 controls the near-infrared light source 1 to turn on and the red light source 4 to turn off, the spectrometer 12 receives the fluorescence and sends the data to the main control circuit board 14, determines whether the detection target object 7 is parathyroid tissue, and sends the detection information to the display terminal 15.

[0039] If the detection target 7 is parathyroid tissue, the main control circuit board 14 controls to simultaneously turn on the near-infrared light source 1 and the red light source 4, and adjusts the luminous power of the infrared light source 1 to match the luminous power of the red light source 4. The spectrometer 12 receives the fluorescence and sends the data to the main control circuit board 14. After processing, the parathyroid blood oxygen and pulse data are obtained and sent to the display terminal 15.

[0040] In a preferred embodiment of the present invention, in the detection method of the above-mentioned spectrometer-based parathyroid identification and blood supply detection device, in judging whether the detection target 7 is parathyroid tissue, the main control circuit board 14 controls to turn on the near-infrared light source 1, turns off the red light source 4, guides the light path to the detection target 7 through the incident optical fiber 6, and receives the autofluorescence and reflected light of the detection target 7 through the receiving optical fiber 8.

[0041] The electrically controlled optical shutter 11 is closed, and the received light is guided to the reflected light fiber 13 through the receiving optical fiber 8 , and the received light is guided to the spectrometer 12 through the reflected light optical fiber 13 .

[0042] The main control circuit board 14 receives the data transmitted by the spectrometer 12 and determines whether the detection target 7 is parathyroid tissue according to a preset algorithm.

[0043] In a preferred embodiment of the present invention, in the detection method of the above-mentioned spectrometer-based parathyroid identification and blood supply detection device, in the detection of parathyroid blood oxygen and pulse data, the main control circuit board 14 controls the simultaneous activation of the near-infrared light source 1 and the red light source 4, and adjusts the luminous power of the infrared light source 1 to match the luminous power of the red light source 4. The infrared light source 1 and the red light source 4 flash alternately at the same frequency, and the on-off duty cycle is 50%.

[0044] The optical paths of the near-infrared light source 1 and the red light source 4 are guided to the detection target 7 through the incident optical fiber 6 , and the reflected light of the detection target 7 is received through the receiving optical fiber 8 .

[0045] The electrically controlled optical shutter 11 is opened to receive the light intensity data of the near-infrared light source 1 and the red light source 4 at corresponding central wavelengths transmitted by the spectrometer 12 .

[0046] The light intensity data when the near-infrared light source 1 is flashed on is recorded as L1, the light intensity data when the red light source 4 is flashed on is recorded as L4, the light intensity data when the near-infrared light source 1 is turned off is recorded as D1, and the light intensity data when the red light source 4 is turned off is recorded as D4. The effective light intensity data after filtering of the near-infrared light source 1 is E1=L1-D1, and the effective light intensity data after filtering of the red light source 4 is E4=L4-D4.

[0047] The main control circuit board 14 uses the effective light intensity data E1 and E4 to obtain parathyroid blood oxygen and pulse data after processing and calculation, and sends the data to the display terminal 15.

[0048] The beneficial effects of the embodiments of the present invention are:

[0049] The spectrometer-based parathyroid gland identification and blood supply detection device and method of the present invention organically integrates the parathyroid gland optical identification and detection optical path with the blood oxygen and pulse detection optical path. This system, combined with a single optical path and a single spectrometer, achieves the dual functions of parathyroid gland identification and blood supply detection. This device boasts a compact structure and low cost. The combined parathyroid gland optical identification and blood supply detection method implemented in this invention is accurate and rapid, making it suitable for use during thyroid surgery. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for use in the embodiments. It should be understood that the following drawings only illustrate certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without paying any creative work.

[0051] Figure 1 This is a schematic diagram of the structure of the parathyroid gland identification and blood supply detection device based on a spectrometer of the present invention;

[0052] Figure 3 The figure is a flow chart of the detection method of the parathyroid gland identification and blood supply detection device based on the spectrometer of the present invention.

[0053] Figure 2 The diagram is a complete flow chart of a method for jointly detecting parathyroid gland identification and its blood supply using a parathyroid gland identification and blood supply detection device based on a spectrometer according to the present invention.

[0054] In the figure: 1-near-infrared light source; 201-first convex lens; 202-second convex lens; 203-third convex lens; 204-fourth convex lens; 205-fifth convex lens; 206-sixth convex lens; 3-near-infrared bandpass filter; 4-red light source; 5-first dichroic mirror; 6-incident optical fiber; 7-detection target; 8-receiving optical fiber; 9-second dichroic mirror; 10-fluorescence bandpass filter; 11-electrically controlled optical shutter; 12-spectrometer; 13-reflected light optical fiber; 14-main control circuit board; 15-display terminal. DETAILED DESCRIPTION

[0055] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings herein can be arranged and designed in various different configurations.

[0056] Please refer to Figure 1The first embodiment of the present invention provides a parathyroid gland identification and blood supply detection device based on a spectrometer, which includes an incident light path, a receiving light path and an optical path analysis module. The incident light path emits light toward the detection target object 7, the receiving light path receives the autofluorescence and reflected light of the detection target object 7, and the optical path analysis module is connected to the incident light path and the receiving light path respectively.

[0057] The incident light path includes a near-infrared light source 1, a red light source 4 and an incident optical fiber 6. The light paths emitted by the infrared light source 1 and the red light source 4 are respectively coupled into the incident optical fiber 6.

[0058] The near-infrared light source 1 has a wavelength between 750-790 nm, typically 785 nm, and can be used independently as an excitation light source for parathyroid fluorescence detection, or in conjunction with the red light source 4 to detect parathyroid blood oxygen and pulse.

[0059] The red light source 4 has a wavelength between 600-700 nm, typically 660 nm, and is used in conjunction with a near-infrared light source to detect parathyroid blood oxygen and pulse signals.

[0060] The receiving optical path includes a receiving optical fiber 8 , an electrically controlled optical shutter 11 and a reflected light optical fiber 13 . The reflected light optical fiber 13 receives the autofluorescence and reflected light of the detection target 7 .

[0061] The optical path analysis module includes a spectrometer 12 and a main control circuit board 14. The reflected light optical fiber 13 guides the light passing through the electrically controlled optical shutter 11 and the receiving optical fiber 8 into the spectrometer 12. The main control circuit board 14 connects the spectrometer 12, the electrically controlled optical shutter 11, the near-infrared light source 1 and the red light source 4.

[0062] The near-infrared light source 1 and the red light source 4 may be laser light sources or non-laser light sources such as LEDs.

[0063] In a preferred embodiment of the present invention, the incident optical fiber 6 of the above-mentioned spectrometer-based parathyroid identification and blood supply detection device guides the near-infrared light emitted by the near-infrared light source 1 and the red light emitted by the red light source 4 to the detection target 7.

[0064] The receiving optical fiber 8 receives the autofluorescence and reflected light of the detection target 7 .

[0065] Wherein, the detection target 7 is parathyroid tissue.

[0066] Among them, the incident optical fiber 6 and the receiving optical fiber 8 can be two independent optical fibers, or a dual-core Y-type optical fiber, or a multi-core Y-type optical fiber with one transmitter and multiple receivers. The incident optical fiber 6 and the receiving optical fiber 8 can also be removed and replaced with spatial light irradiation and reception.

[0067] Preferably, the optical fiber measuring portion can be made into a slender straight probe or a probe shape with a certain curvature to facilitate measurement.

[0068] The technical effect thereof is that it is used to illuminate the detection target object 7 and perform optical recognition by receiving the autofluorescence and reflected light of the detection target object 7.

[0069] In a preferred embodiment of the present invention, the incident light path of the above-mentioned parathyroid gland identification and blood supply detection device based on a spectrometer further includes a near-infrared bandpass filter 3 and a first dichroic mirror 5 .

[0070] The near-infrared bandpass filter 3 is arranged on the light-emitting side of the near-infrared light source 1 .

[0071] The first dichroic mirror 5 is tiltedly disposed on the light-emitting side of the near-infrared light source 1 and the light-emitting side of the red light source 4 .

[0072] The input optical fiber 6 receives the light passing through and reflected by the first dichroic mirror 5 .

[0073] The technical effect is that the bandpass filter only allows light of a specific wavelength band to pass through. The near-infrared bandpass filter 3 allows near-infrared light to pass through.

[0074] The dichroic mirror almost completely transmits certain wavelengths of light and almost completely reflects other wavelengths of light. The initial response wavelength of the first dichroic mirror 5 is between the wavelength of the near-infrared light source and the wavelength of the red light source, allowing the near-infrared light to pass through and reflecting the red light.

[0075] In a preferred embodiment of the present invention, a first convex lens 201 is provided between the near-infrared light source 1 and the near-infrared bandpass filter 3 of the parathyroid gland identification and blood supply detection device based on a spectrometer.

[0076] A second convex lens 202 is provided between the red light source 4 and the first dichroic mirror 5 .

[0077] A third convex lens 203 is provided between the first dichroic mirror 5 and the incident optical fiber 6 .

[0078] The technical effect is that a convex lens is provided to achieve collimation or focusing of light.

[0079] In a preferred embodiment of the present invention, the receiving light path of the above-mentioned parathyroid gland identification and blood supply detection device based on a spectrometer further includes a fluorescence bandpass filter 10 and a second dichroic mirror 9 .

[0080] The second dichroic mirror 9 is tilted and arranged on the light-emitting side of the receiving optical fiber 8 .

[0081] The fluorescent bandpass filter 10 is arranged on the light-transmitting side of the second dichroic mirror 9 .

[0082] The electrically controlled optical shutter 11 is disposed on the light reflecting side of the second dichroic mirror 9 .

[0083] The technical effect is that the fluorescent bandpass filter 10 is used to pass parathyroid fluorescence and cut off stray light in other bands. The electrically controlled optical shutter 11 is opened and closed by electrical control, allowing light to pass when opened and blocking the light when closed.

[0084] In a preferred embodiment of the present invention, the reflected light fiber 13 of the above-mentioned parathyroid gland identification and blood supply detection device based on a spectrometer receives the light passing through and reflected from the second dichroic mirror 9 and guides the light into the spectrometer 12 .

[0085] In a preferred embodiment of the present invention, a fourth convex lens 204 is provided between the receiving optical fiber 8 and the second dichroic mirror 9 of the parathyroid gland identification and blood supply detection device based on a spectrometer.

[0086] A fifth convex lens 205 is provided between the electrically controlled optical shutter 11 and the reflecting light optical fiber 13 .

[0087] A sixth convex lens 206 is provided between the fluorescence bandpass filter 10 and the reflected light optical fiber 13 .

[0088] In a preferred embodiment of the present invention, the electrically controlled optical shutter 11 of the above-mentioned spectrometer-based parathyroid gland identification and blood supply detection device is opened, and the light of the receiving optical fiber 8 is reflected by the second dichroic mirror 9 and then connected to the reflected light optical fiber 13.

[0089] The electrically controlled optical shutter 11 is closed, blocking the light reflected by the second dichroic mirror 9 .

[0090] In a preferred embodiment of the present invention, the light of the receiving optical fiber 8 of the above-mentioned spectrometer-based parathyroid gland identification and blood supply detection device passes through the second dichroic mirror 9, passes through the fluorescent bandpass filter 10, and is connected to the reflected light optical fiber 13.

[0091] In a preferred embodiment of the present invention, the optical path analysis module of the above-mentioned spectrometer-based parathyroid identification and blood supply detection device also includes a display terminal 15, which is connected to the main control circuit board 14 to display an operation interface and parathyroid fluorescence, blood oxygen, and pulse data.

[0092] Its technical effect is: through the main control circuit board 14, it drives and controls the opening and closing of the two light sources and modulates their respective luminous intensities, controls the opening and closing of the electric shutter, receives data from the spectrometer and performs calculations and analysis according to a certain algorithm, and outputs information related to fluorescence, blood oxygen, and pulse to the display terminal 15.

[0093] Please refer to Figures 1 to 3 The second embodiment of the present invention provides a parathyroid gland identification and blood supply detection device based on a spectrometer for a joint detection method of parathyroid gland identification and its blood supply.

[0094] like Figure 2 As shown, the detection method of the parathyroid gland identification and blood supply detection device based on the spectrometer as described above includes:

[0095] The detection optical fiber is placed close to the detection target object 7, the main control circuit board 14 controls the near-infrared light source 1 to turn on and the red light source 4 to turn off, the spectrometer 12 receives the fluorescence and sends the data to the main control circuit board 14, determines whether the detection target object 7 is parathyroid tissue, and sends the detection information to the display terminal 15.

[0096] If the detection target 7 is parathyroid tissue, the main control circuit board 14 controls to simultaneously turn on the near-infrared light source 1 and the red light source 4, and adjusts the luminous power of the infrared light source 1 to match the luminous power of the red light source 4. The spectrometer 12 receives the fluorescence and sends the data to the main control circuit board 14. After processing, the parathyroid blood oxygen and pulse data are obtained and sent to the display terminal 15.

[0097] like Figure 3 As shown, in a preferred embodiment of the present invention, in the detection method of the parathyroid gland identification and blood supply detection device based on a spectrometer, the determination of whether the detection target 7 is parathyroid gland tissue includes:

[0098] The main control circuit board 14 controls to turn on the near-infrared light source 1 and turn off the red light source 4, guides the light path to the detection target 7 through the incident optical fiber 6, and receives the autofluorescence and reflected light of the detection target 7 through the receiving optical fiber 8.

[0099] The electrically controlled optical shutter 11 is closed (the reflected light path of the dichroic mirror 9 is blocked), and the received light is guided to the reflected light fiber 13 through the receiving optical fiber 8 , and then introduced into the spectrometer 12 through the reflected light fiber 13 .

[0100] The near-infrared light, serving as the excitation light for the parathyroid glands, is collimated by the first convex lens 201 and filtered by the near-infrared bandpass filter 3 to remove components outside the excitation band. It then passes through the first dichroic mirror 5 and is focused by the third convex lens 203 onto the incident fiber 6. The incident fiber 6 directs the excitation light to the surface of the tissue being measured. If the tissue being measured is the parathyroid gland, it produces a stronger fluorescence with a peak wavelength of 820 nm than other tissues. This fluorescence, along with other stray light, is received by the receiving fiber 8. The receiving fiber 8 directs the received light into the receiving optical path. After collimation by the fourth convex lens 204, the second dichroic mirror 9 and the fluorescence bandpass filter 10 filter out stray light, allowing only the wavelength near 820 nm to pass. The light is then focused by the fifth convex lens 205 onto the transmission branch of the Y-shaped reflective fiber 13, which then directs the fluorescence into the spectrometer 12.

[0101] The main control circuit board 14 receives the data transmitted by the spectrometer 12 and determines whether the detection target 7 is parathyroid tissue according to a preset algorithm.

[0102] In a preferred embodiment of the present invention, in the detection method of the parathyroid gland identification and blood supply detection device based on a spectrometer, the detection of parathyroid gland blood oxygen and pulse data includes:

[0103] The main control circuit board 14 controls to turn on the near-infrared light source 1 and the red light source 4 at the same time, and adjusts the luminous power of the infrared light source 1 to match the luminous power of the red light source 4. The infrared light source 1 and the red light source 4 flash alternately at the same frequency, and the on-off duty cycle is 50%.

[0104] The optical paths of the near-infrared light source 1 and the red light source 4 are guided to the detection target 7 via the incident optical fiber 6, and the reflected light from the detection target 7 is received via the receiving optical fiber 8. The electrically controlled optical shutter 11 is opened (the reflected light path of the dichroic mirror 9 is in an open state), and the light intensity data at the corresponding center wavelengths of the near-infrared light source 1 and the red light source 4 transmitted by the spectrometer 12 is received.

[0105] The main control circuit board 1314 modulates the luminous power of light source 1 to a level that matches that of red light source 4, and controls the near-infrared light source 1 to flash at the same frequency as the red light source 4 (alternating between on and off). The near-infrared light is collimated by the first convex lens 201 and the near-infrared bandpass filter 3 before passing through the first dichroic mirror 5 and being focused by the third convex lens 203 onto the incident optical fiber 6. Simultaneously, the red light is collimated by the lens, reflected by the first dichroic mirror 5, and focused by the second convex lens 202 before also being focused into the incident optical fiber 6. The incident optical fiber 6 directs the two wavelengths of light to the surface of the tissue being measured. Part of the incident light is absorbed by the tissue, while the remaining part is reflected by the tissue and received by the receiving optical fiber 8. The receiving optical fiber 8 introduces the received light into the receiving optical path. After being collimated by the fourth convex lens 204, it is reflected by the second dichroic mirror 9 and finally focused by the fifth convex lens 205 onto the reflection branch of the reflected light optical fiber 13. The reflected light optical fiber 13 then directs the reflected light into the spectrometer 12.

[0106] The light intensity data when the near-infrared light source 1 is flashed on is recorded as L1, the light intensity data when the red light source 4 is flashed on is recorded as L4, the light intensity data when the near-infrared light source 1 is turned off is recorded as D1, and the light intensity data when the red light source 4 is turned off is recorded as D4. The effective light intensity data after filtering of the near-infrared light source 1 is E1=L1-D1, and the effective light intensity data after filtering of the red light source 4 is E4=L4-D4.

[0107] The main control circuit board 14 uses the effective light intensity data E1 and E4 to process and calculate parathyroid blood oxygen and pulse data, which are then transmitted to the display terminal 15 for the doctor to determine the blood supply status of the tissue being tested. Although some light from the transmission branch of the reflected light fiber 13 is captured by the spectrometer 12, it is very weak compared to the intensity of the reflected light and does not affect the measurement of parathyroid blood oxygen and pulse parameters. The embodiments of the present invention are intended to protect a parathyroid gland identification and blood supply detection device and method based on a spectrometer, which has the following effects:

[0108] By organically integrating the parathyroid gland optical identification and detection optical path with the blood oxygen and pulse detection optical paths, this system, combined with a single optical path and a single spectrometer, achieves the dual functions of parathyroid gland identification and blood supply detection. This system boasts a compact structure and low cost. The combined parathyroid gland optical identification and blood supply detection method implemented in this invention is accurate and rapid, making it suitable for use during thyroid surgery.

[0109] It should be understood that the above-described specific embodiments of the present invention are merely illustrative or illustrative of the principles of the present invention and do not constitute limitations of the present invention. Therefore, any modifications, equivalent substitutions, improvements, etc. made without departing from the spirit and scope of the present invention should be included within the scope of protection of the present invention. In addition, the appended claims are intended to cover all variations and modifications that fall within the scope and metes and bounds of the appended claims, or equivalents thereof.

Claims

1. A parathyroid gland identification and blood supply detection device based on a spectrometer, characterized in that: It comprises an incident light path, a receiving light path and a light path analysis module, wherein the incident light path transmits a light path toward a detection target object (7), the receiving light path receives the autofluorescence and reflected light of the detection target object (7), and the light path analysis module is connected to the incident light path and the receiving light path respectively; The incident light path comprises a near-infrared light source (1), a red light source (4) and an incident optical fiber (6), and the light paths emitted by the near-infrared light source (1) and the red light source (4) are respectively coupled into the incident optical fiber (6); The receiving optical path comprises a receiving optical fiber (8), an electrically controlled optical shutter (11) and a reflected light optical fiber (13), wherein the reflected light optical fiber (13) receives the autofluorescence and reflected light of the detection target object (7); The optical path analysis module includes a spectrometer (12) and a main control circuit board (14); the reflected light optical fiber (13) guides the light passing through the electrically controlled optical shutter (11) and the receiving optical fiber (8) into the spectrometer (12); and the main control circuit board (14) is connected to the spectrometer (12), the electrically controlled optical shutter (11), the near-infrared light source (1), and the red light source (4); The incident light path further comprises a near-infrared bandpass filter (3) and a first dichroic mirror (5); The near-infrared bandpass filter (3) is arranged on the light-emitting side of the near-infrared light source (1); The first dichroic mirror (5) is arranged obliquely on the light-emitting side of the near-infrared light source (1) and the light-emitting side of the red light source (4); The incident optical fiber (6) receives the light passing through and reflected by the first dichroic mirror (5); A first convex lens (201) is provided between the near-infrared light source (1) and the near-infrared bandpass filter (3); A second convex lens (202) is provided between the red light source (4) and the first dichroic mirror (5); A third convex lens (203) is provided between the first dichroic mirror (5) and the incident optical fiber (6); The receiving light path further comprises a fluorescence bandpass filter (10) and a second dichroic mirror (9); The second dichroic mirror (9) is arranged obliquely on the light-emitting side of the receiving optical fiber (8); The fluorescent bandpass filter (10) is arranged on the light-passing side of the second dichroic mirror (9); The electrically controlled optical shutter (11) is arranged on the light reflecting side of the second dichroic mirror (9); The reflected light optical fiber (13) receives the light passing through and reflected from the second dichroic mirror (9) and guides the light into the spectrometer (12); A fourth convex lens (204) is provided between the receiving optical fiber (8) and the second dichroic mirror (9); A fifth convex lens (205) is provided between the electrically controlled optical shutter (11) and the reflected light optical fiber (13); A sixth convex lens (206) is provided between the fluorescent bandpass filter (10) and the reflected light optical fiber (13).

2. The parathyroid gland identification and blood supply detection device based on a spectrometer according to claim 1, characterized in that: The incident optical fiber (6) guides the near-infrared light emitted by the near-infrared light source (1) and the red light emitted by the red light source (4) to the detection target (7); The receiving optical fiber (8) receives the autofluorescence and reflected light of the detection target object (7).

3. The parathyroid gland identification and blood supply detection device based on a spectrometer according to claim 1, characterized in that: The electrically controlled optical shutter (11) is opened, and the light from the receiving optical fiber (8) is reflected by the second dichroic mirror (9) and then connected to the reflected light optical fiber (13); The electrically controlled optical shutter (11) is closed, blocking the light reflected by the second dichroic mirror (9); The light from the receiving optical fiber (8) passes through the second dichroic mirror (9), passes through the fluorescence bandpass filter (10), and is connected to the reflected light optical fiber (13).

4. The parathyroid gland identification and blood supply detection device based on a spectrometer according to claim 1, characterized in that: The optical path analysis module further comprises a display terminal (15), which is connected to the main control circuit board (14) and displays an operation interface and parathyroid fluorescence, blood oxygen, and pulse data.

5. A detection method for the parathyroid gland identification and blood supply detection device based on a spectrometer according to any one of claims 1 to 4, characterized in that: include: The detection optical fiber is placed close to the detection target object (7), the main control circuit board (14) controls the near-infrared light source (1) to be turned on, and the red light source (4) to be turned off, the spectrometer (12) receives the fluorescence and sends the data to the main control circuit board (14), determines whether the detection target object (7) is parathyroid tissue, and sends the detection information to the display terminal (15); If the detection target (7) is parathyroid tissue, the main control circuit board (14) controls the near-infrared light source (1) and the red light source (4) to be turned on simultaneously, and adjusts the luminous power of the near-infrared light source (1) to match the luminous power of the red light source (4). The spectrometer (12) receives the fluorescence and sends the data to the main control circuit board (14). After processing, the parathyroid blood oxygen and pulse data are obtained and sent to the display terminal (15).

6. The detection method of the parathyroid gland identification and blood supply detection device based on a spectrometer according to claim 5, characterized in that: In determining whether the detection target (7) is parathyroid tissue, the main control circuit board (14) controls the near-infrared light source (1) to be turned on, the red light source (4) to be turned off, the light path to be guided to the detection target (7) via the incident optical fiber (6), and the autofluorescence and reflected light of the detection target (7) to be received via the receiving optical fiber (8); closing the electrically controlled optical shutter (11), guiding the received light to the reflected light optical fiber (13) via the receiving optical fiber (8), and guiding the received light to the spectrometer (12) via the reflected light optical fiber (13); The main control circuit board (14) receives data transmitted by the spectrometer (12) and determines whether the detection target object (7) is parathyroid tissue according to a preset algorithm.

7. The detection method of the parathyroid gland identification and blood supply detection device based on a spectrometer according to claim 5, characterized in that: In the detection of parathyroid blood oxygen and pulse data, the main control circuit board (14) controls the simultaneous activation of the near-infrared light source (1) and the red light source (4), adjusts the luminous power of the near-infrared light source (1) and the luminous power of the red light source (4) to match, and the near-infrared light source (1) and the red light source (4) flash alternately at the same frequency, with an on-off duty cycle of 50%; The optical paths of the near-infrared light source (1) and the red light source (4) are guided to the detection target object (7) via the incident optical fiber (6), and the reflected light of the detection target object (7) is received via the receiving optical fiber (8); Opening the electrically controlled optical shutter (11) to receive light intensity data of the near-infrared light source (1) and the red light source (4) at corresponding central wavelengths transmitted by the spectrometer (12); The light intensity data when the near-infrared light source (1) is flashing on is recorded as L1, the light intensity data when the red light source (4) is flashing on is recorded as L4, the light intensity data when the near-infrared light source (1) is extinguished is recorded as D1, the light intensity data when the red light source (4) is extinguished is recorded as D4, the effective light intensity data after filtering of the near-infrared light source (1) is E1=L1-D1, and the effective light intensity data after filtering of the red light source (4) is E4=L4-D4; The main control circuit board (14) uses the effective light intensity data E1 and E4 to obtain parathyroid blood oxygen and pulse data after processing and calculation, and sends the data to the display terminal (15).

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