Method, device and equipment for controlling diaphragm pump liquid suction, and nonvolatile storage medium

Abstract

The application discloses a kind of diaphragm pump liquid suction control method, device, equipment and nonvolatile storage medium.Therein, the method includes: according to the liquid target flow required by liquid suction operation, determine the driving power range of the diaphragm pump used by liquid suction operation;Obtain the operation parameters of liquid suction operation, wherein the operation parameters include: suction liquid amount range, operation duration and liquid residual amount threshold;According to operation parameters, determine the actual power range corresponding to liquid suction operation in driving power range;According to the driving power range of diaphragm pump, determine target buffer, wherein target buffer is used to buffer the pulse fluctuation of diaphragm pump;Target buffer is set to the liquid suction end of diaphragm pump;Control diaphragm pump to execute liquid suction operation using target power in actual power range.The application solves the technical problem that there is no diaphragm pump scheme when performing liquid suction operation with high precision in the related art.

Description

Technical Field

[0001] The present invention relates to the field of medical equipment, and in particular to a method, device, equipment and non-volatile storage medium for controlling liquid suction by a diaphragm pump. Background Art

[0002] In in vitro detection equipment, magnetic separation technology is often used to extract target objects. In magnetic separation technology, corresponding reagents are used to wash the magnetic beads bound to specific markers. After washing, the magnetic beads are adsorbed on the wall of the reaction vessel, and the waste liquid after washing is sucked out by a suction pump. The mainstream suction pump is a peristaltic pump. Its advantage is that the suction precision control is precise, and its disadvantage is that the suction speed is slow and the cost is high. Although peristaltic pumps have the above-mentioned shortcomings, diaphragm pumps with low prices and fast suction speeds are rarely used on the market to replace peristaltic pumps. The reason is that the working principle of the diaphragm pump relies on the back and forth agitation of a diaphragm to change the volume of the working chamber to inhale and discharge liquid. Therefore, when the diaphragm pump absorbs liquid, it often forms a large negative pressure, forming a pulse, causing liquid disturbance in the reaction vessel, causing the magnetic beads to detach from the wall of the reaction vessel, thereby causing the loss of magnetic beads, and ultimately affecting the experimental results. In addition, the standard flow rate of the diaphragm pump allows a large error range. The error between the actual flow rate and the standard flow rate is between 90% and 110%. In in vitro diagnostic technology, the volume of the solution is often only a few microliters or a few milliliters. If a diaphragm pump is selected according to its nominal flow rate, there may be a large deviation between the nominal flow rate and the actual flow rate. Summary of the Invention

[0003] Embodiments of the present invention provide a control method, device, liquid suction equipment and non-volatile storage medium for a diaphragm pump to at least solve the technical problem in the related art of lacking a diaphragm pump solution when performing liquid suction operations with high precision.

[0004] According to one aspect of an embodiment of the present invention, a method for controlling liquid suction by a diaphragm pump is provided, comprising: determining a driving power range of a diaphragm pump used in the liquid suction operation according to a target liquid flow rate required for the liquid suction operation; obtaining operation parameters of the liquid suction operation, wherein the operation parameters include: a suction volume range, operation duration, and a liquid residual threshold; determining an actual power range corresponding to the liquid suction operation within the driving power range according to the operation parameters; determining a target buffer according to the driving power range of the diaphragm pump, wherein the target buffer is used to buffer the pulse fluctuations of the diaphragm pump; setting the target buffer at the liquid suction end of the diaphragm pump; and controlling the diaphragm pump to use a target power within the actual power range to perform the liquid suction operation. The above method can achieve the technical effect of providing a high-precision diaphragm pump solution for liquid suction operations.

[0005] Optionally, the driving power range of the diaphragm pump used in the liquid suction operation is determined according to a target flow required by the liquid suction operation, comprising: determining a flow margin value according to a liquid target flow required by the liquid suction operation and a flow margin ratio, wherein the flow margin ratio is greater than 1; determining the diaphragm pump according to the flow margin value, wherein a nominal flow of the diaphragm pump matches the flow margin value; determining a first power corresponding to a minimum flow of the diaphragm pump; determining a second power corresponding to a maximum flow of the diaphragm pump, wherein the second power is a floating lower limit of the nominal flow of the diaphragm pump; and determining the driving power range according to the first power and the second power. Through the above optional method, a more reliable diaphragm pump can be matched for the liquid suction operation, and the correspondence between the power and the flow of the diaphragm pump can be accurately calibrated.

[0006] Optionally, the actual power range of the liquid suction operation is determined within the driving power range according to the operation parameters, comprising: controlling the diaphragm pump to suck a first liquid in a test tube using the first power within the operation time length, and determining a residual amount of the first liquid in the test tube, wherein the liquid amount of the first liquid in the test tube is the minimum value in the suction liquid amount range; in the case that the residual amount of the first liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above operation of sucking the first liquid until a third power is obtained, wherein the residual amount of the first liquid in the test tube when the diaphragm pump is controlled to suck the first liquid using the third power is less than or equal to the residual amount threshold; controlling the diaphragm pump to suck a second liquid in the test tube using the first power within the operation time length, and determining a residual amount of the second liquid in the test tube, wherein the liquid amount of the second liquid in the test tube is the maximum value in the suction liquid amount range; in the case that the residual amount of the second liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above operation of sucking the second liquid until a fourth power is obtained, wherein the residual amount of the second liquid in the test tube when the diaphragm pump is controlled to suck the second liquid using the fourth power is less than or equal to the residual amount threshold, and the fourth power is less than the second power; and determining the actual power range according to the third power and the fourth power. Through the above optional method, the technical effect of ensuring that the residual amount of liquid meets the requirements in the operation requirements when the diaphragm pump performs the liquid suction operation can be achieved, and the residual liquid in the test tube after the diaphragm pump performs the operation can be avoided.

[0007] Optionally, determining the actual power range based on the third power and the fourth power includes: when the operating parameters of the liquid absorption operation include a magnetic bead loss rate threshold, within the operation duration, controlling the diaphragm pump to use the fourth power to absorb the first liquid in the test tube, and determining the magnetic bead loss rate after absorbing the first liquid; when the magnetic bead loss rate after absorbing the first liquid is greater than the magnetic bead loss rate threshold, gradually reducing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the first liquid until a fifth power is obtained, wherein the magnetic bead loss rate after controlling the diaphragm pump to use the fifth power to absorb the first liquid is less than or equal to the magnetic bead loss rate threshold, the fifth power is greater than or equal to the third power; within the operation time, the diaphragm pump is controlled to use the fourth power to absorb the second liquid in the test tube, and the magnetic bead loss rate after absorbing the second liquid is determined; when the magnetic bead loss rate after absorbing the second liquid is greater than the magnetic bead loss rate threshold, the power of the diaphragm pump is gradually reduced and the above-mentioned operation of absorbing the second liquid is repeated until the sixth power is obtained, wherein the magnetic bead loss rate after controlling the diaphragm pump to use the sixth power to absorb the second liquid is less than or equal to the magnetic bead loss rate threshold, and the sixth power is greater than the third power; the actual power range is determined based on the fifth power and the sixth power. Through the above optional method, the technical effect of meeting the magnetic bead loss rate requirements in the operation requirements when the pillow diaphragm pump performs the liquid absorption operation can be achieved, and the excessive magnetic bead loss rate in the test tube after the diaphragm pump performs the operation can be avoided, thereby avoiding the destruction of the test results.

[0008] Optionally, the target buffer is determined according to the driving power range of the diaphragm pump, including: setting a first number of initial buffers at the liquid suction end of the diaphragm pump, wherein the initial buffers have a first diameter; in a case that the diaphragm pump is controlled to perform the liquid suction operation with a minimum value in the driving power range, performing a test that whether the liquid flow is smooth when the diaphragm pump sucks liquid through the first number of initial buffers, until the liquid flow is smooth when the diaphragm pump sucks liquid through a second number of initial buffers, by gradually increasing the first number; obtaining a third number by subtracting a predetermined number from the second number; testing whether the liquid flow is smooth when the diaphragm pump sucks liquid through the third number of test buffers, by gradually increasing the diameter of the test buffer, until the liquid flow is smooth when the diaphragm pump sucks liquid through the third number of test buffers with a second diameter, wherein the initial value of the diameter of the test buffer is the first diameter; determining the target buffer, wherein the target buffer includes the third number of buffers with the second diameter. Through the above optional method, the most suitable buffer scheme for the diaphragm pump can be realized, and a technical effect of balancing the number of modules and the pipe diameter of the buffer is achieved.

[0009] Optionally, the method further includes: determining a relationship between the flow and the driving power output of the diaphragm pump in the actual power range according to a minimum flow L_1 of the diaphragm pump, a first power P_1 corresponding to the minimum flow L_1, a maximum flow L_2 of the diaphragm pump, and a second power P_2 corresponding to the maximum flow L_2. According to the liquid suction flow L' of the liquid suction operation, the target power is determined as K*L'.

[0010] According to another aspect of the embodiment of the present application, a diaphragm pump liquid suction control device is also provided, including: a first determination module configured to determine a driving power range of a diaphragm pump for a liquid suction operation according to a target liquid flow required by the liquid suction operation; an acquisition module configured to acquire operation parameters of the liquid suction operation, wherein the operation parameters include: a liquid suction amount range, an operation duration, and a liquid residual amount threshold; a second determination module configured to determine an actual power range corresponding to the liquid suction operation in the driving power range according to the operation parameters; a third determination module configured to determine a target buffer according to the driving power range of the diaphragm pump, and to set the target buffer at the liquid suction end of the diaphragm pump, wherein the target buffer is used to buffer pulse fluctuations of the diaphragm pump; and a control module configured to control the diaphragm pump to perform the liquid suction operation with a target power in the actual power range.

[0011] According to another aspect of an embodiment of the present invention, a diaphragm pump liquid suction device is also provided, including: a diaphragm pump, a target buffer, a liquid suction needle, a one-way valve and the above-mentioned diaphragm pump liquid suction control device, wherein the liquid suction needle is connected to the target buffer, the target buffer is connected to the liquid suction end of the diaphragm pump, the liquid discharge end of the diaphragm pump is connected to the one-way valve, and the diaphragm pump liquid suction control device is electrically connected to the diaphragm pump.

[0012] According to another aspect of an embodiment of the present invention, a non-volatile storage medium is further provided, wherein the non-volatile storage medium includes a stored program, wherein when the program is running, the device where the non-volatile storage medium is located is controlled to execute any one of the above-mentioned methods for controlling liquid suction by a diaphragm pump.

[0013] According to another aspect of an embodiment of the present invention, a computer device is further provided, comprising a memory and a processor, wherein the memory is used to store programs, and the processor is used to run the programs stored in the memory, wherein when the program is run, any one of the above-mentioned methods for controlling liquid suction by a diaphragm pump is executed.

[0014] In an embodiment of the present invention, the actual working state of the diaphragm pump is accurately nominally measured. By obtaining the operating parameters of the liquid suction operation and matching the actual working state of the diaphragm pump according to the operating parameters of the liquid suction operation, the purpose of controlling the diaphragm pump to accurately perform the liquid suction operation is achieved, thereby achieving the technical effect of providing a high-precision diaphragm pump solution for the liquid suction operation, and further solving the technical problem of the lack of diaphragm pump solutions when performing liquid suction operations with higher precision in related technologies. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of this application. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the drawings:

[0016] Figure 1 1 is a flow chart of a method for controlling liquid suction by a diaphragm pump according to an embodiment of the present invention;

[0017] Figure 2 is a schematic diagram of a diaphragm pump control circuit according to an optional embodiment of the present invention;

[0018] Figure 3 is a schematic diagram of a flow chart for determining a corresponding relationship between flow and power according to an optional embodiment of the present invention;

[0019] Figure 4 is a schematic diagram of a process for determining a third power based on a residual liquid amount according to an optional embodiment of the present invention;

[0020] Figure 5 is a schematic diagram of a process for determining a fifth power based on a residual liquid amount according to an optional embodiment of the present invention;

[0021] Figure 6 is a schematic diagram of a method for screening a target buffer according to an optional embodiment of the present invention;

[0022] Figure 7 is a flow chart of a liquid aspirating operation control method according to an optional embodiment of the present invention;

[0023] Figure 8 2 is a structural block diagram of a liquid suction operation control device provided according to an embodiment of the present invention;

[0024] Figure 9 is a schematic diagram of a diaphragm pump liquid suction device according to an optional embodiment of the present invention;

[0025] Figure 10 The present invention shows a hardware structure block diagram of a computer terminal for realizing a control method for liquid aspiration by a diaphragm pump. DETAILED DESCRIPTION

[0026] In order to enable those skilled in the art to better understand the solutions of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts should fall within the scope of protection of the present invention.

[0027] It should be noted that the terms "first", "second", etc. in the description and claims of the present invention and the above-mentioned drawings are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchanged where appropriate, so that the embodiments of the present invention described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0028] According to an embodiment of the present invention, an embodiment of a method for controlling a liquid suction operation is provided. It should be noted that the steps shown in the flowchart of the accompanying drawings can be executed in a computer system such as a set of computer-executable instructions, and although a logical order is shown in the flowchart, in some cases, the steps shown or described can be executed in an order different from that shown here.

[0029] In in vitro detection equipment, magnetic separation technology is often used to extract target objects. In magnetic separation technology, corresponding reagents are used to wash the magnetic beads bound to specific markers. After washing, the magnetic beads are adsorbed on the wall of the reaction vessel, and the waste liquid after washing is sucked out by a suction pump. The mainstream suction pump is a peristaltic pump. Its advantage is that the suction precision control is precise, and its disadvantage is that the suction speed is slow and the cost is high. Although peristaltic pumps have the above-mentioned shortcomings, diaphragm pumps with low prices and fast suction speeds are rarely used on the market to replace peristaltic pumps. The reason is that the working principle of the diaphragm pump relies on the back and forth agitation of a diaphragm to change the volume of the working chamber to inhale and discharge liquid. Therefore, when the diaphragm pump absorbs liquid, it often forms a large negative pressure, forming a pulse, causing liquid disturbance in the reaction vessel, causing the magnetic beads to detach from the wall of the reaction vessel, thereby causing the loss of magnetic beads, and ultimately affecting the experimental results. Diaphragm pumps have poor aspiration accuracy. When using a diaphragm pump for aspiration, it's often found that the pump doesn't achieve the required aspiration power, or its actual power far exceeds the required aspiration power. Underachieving this power can lead to incomplete aspiration, affecting the results of the next experiment; excessive aspiration power can cause disturbances, leading to bead loss and affecting experimental values. Furthermore, for different liquid volumes, even slight differences between, say, 400µL and 600µL, the aspiration speed requirements vary. However, diaphragm pumps are characterized by low precision (factory standards typically set them at 90%-110% of the maximum flow rate) and poor control (flow rate control can be achieved by adjusting the PWM pulse width, but this results in pulsed fluctuations). This makes direct aspiration speed control difficult. Therefore, diaphragm pumps struggle to meet the requirements for high-precision aspiration, making them unsuitable for high-precision aspiration.

[0030] The present invention provides a control method for liquid aspiration by a diaphragm pump, which is used to support the diaphragm pump to accurately aspirate liquid in a test tube, thereby meeting the liquid aspiration accuracy requirement for the magnetic separation process step in the enzymatic chemiluminescence technology. Figure 1 FIG. 1 is a flow chart of a method for controlling liquid suction by a diaphragm pump according to an embodiment of the present invention. Figure 1 As shown, the method includes the following steps:

[0031] Step S102 : determining a driving power range of a diaphragm pump used in the liquid suction operation according to a target liquid flow rate required for the liquid suction operation.

[0032] The liquid aspiration operation involves precisely aspirating liquid from a test tube. This type of operation requires high performance. Directly connecting the diaphragm pump to the power supply to aspirate the liquid from the test tube cannot guarantee that the aspiration process will meet the requirements of this liquid aspiration operation, as the actual power of the diaphragm pump fluctuates significantly compared to the nominal power. The target flow rate for this liquid aspiration operation is the maximum flow rate required to aspirate the liquid in this operation. For example, the volume of liquid in a test tube may range from 100μl to 800μl. Clearly, the greater the volume of liquid, the greater the flow rate required to aspirate the liquid within the specified time. Therefore, the target flow rate corresponding to 800μl is the target flow rate required for this liquid aspiration operation.

[0033] The driving power range of a diaphragm pump refers to the power range within which the diaphragm pump can be driven to complete the suction work. For example, if the actual power of the diaphragm pump is insufficient, the diaphragm pump may not work at all. Only when the actual power of the diaphragm pump exceeds a certain threshold, such as more than half of the nominal power of the diaphragm pump, can the diaphragm pump start working. The actual power of the diaphragm pump at this time is determined as the lower limit of the driving power range of the diaphragm pump.

[0034] As an optional embodiment, the driving power range of the diaphragm pump used in the liquid suction operation can be determined by the following steps: determining the flow margin value based on the liquid target flow and flow margin ratio required for the liquid suction operation, wherein the flow margin ratio is greater than 1; determining the diaphragm pump based on the flow margin value, wherein the nominal flow of the diaphragm pump matches the flow margin value; measuring the first power corresponding to the minimum flow of the diaphragm pump; measuring the second power corresponding to the maximum flow of the diaphragm pump, wherein the second power is the floating lower limit of the nominal flow of the diaphragm pump; and determining the driving power range based on the first power and the second power.

[0035] In this optional embodiment, a diaphragm pump can be matched for the liquid suction operation first, and then the drive power range of the diaphragm pump can be examined. Optionally, the diaphragm pump can be matched based on its nominal flow rate and flow margin ratio. The flow margin ratio can be selected as 1.2, 1.25, 1.3, 1.35, etc. The specific flow margin ratio can be determined based on factors such as the suction operation environment and the total amount of liquid to be sucked. This is to avoid the situation where the diaphragm pump's maximum actual flow rate fails to reach its nominal flow rate, resulting in an inability to complete the liquid suction operation. This problem arises because diaphragm pumps are not designed for high-precision liquid suction operations, and therefore their actual flow rate and nominal flow rate often deviate. It should be noted that the term "margin" in this optional embodiment means that the nominal flow rate of the matched diaphragm pump is greater than the target flow rate required for the liquid suction operation, so that the matched diaphragm pump does not face the pressure of insufficient flow when handling the liquid suction operation. The flow margin ratio represents the ratio between the maximum flow rate that the diaphragm pump can actually provide and the maximum flow rate required for the liquid suction operation. In this step, a flow margin value can be determined first, and this value is greater than the target liquid flow rate. Then, a diaphragm pump with a nominal flow rate that matches this flow margin value is selected to ensure that the diaphragm pump does not have an actual maximum flow rate that is insufficient.

[0036] Figure 2 Schematic diagram of a diaphragm pump control circuit according to an optional embodiment of the present invention, Figure 2 As shown, R1 and R2 are resistors, Q1 is a MOS tube, D1 is a diode, and J1 is a 2-pin interface; the diaphragm pump is connected to J1, and the microcontroller controls the opening and closing of the diaphragm pump and the energy power provided to the diaphragm pump through the signal "CTRL1".

[0037] As an optional implementation, you can first calculate the maximum flow rate required for the liquid suction operation, that is, calculate the target liquid flow rate, and select a diaphragm pump with a nominal flow rate that exceeds the maximum required flow rate by a margin of A%. (If the diaphragm pump range is too large, it may cause flow pulsation when the diaphragm pump is operating at low flow rates. If the diaphragm pump range is too small, the suction effect will not be achieved.) A% can be selected as 20%. For example, if the required maximum instantaneous flow rate is 2000 μL / s (i.e., 120 mL / min), the nominal flow rate of the matching diaphragm pump is selected based on 120*(1+20%)=144. Therefore, a diaphragm pump with a nominal flow rate between 140-150 mL / min can be selected.

[0038] Furthermore, the diaphragm pump powers corresponding to the maximum flow rate and minimum flow rate of the diaphragm pump can be measured in turn, wherein the maximum flow rate of the diaphragm pump is the maximum flow rate that the diaphragm pump can provide under normal working conditions; the minimum flow rate of the diaphragm pump is the energy power provided to the diaphragm pump that is gradually increased from the power at which the diaphragm pump cannot normally absorb liquid until the diaphragm pump just starts to absorb liquid. At this time, the liquid suction flow rate provided by the diaphragm pump is the minimum flow rate, and the power of the diaphragm pump is the first power.

[0039] As an optional implementation, the process of obtaining the driving power range of the diaphragm pump may not focus on whether the suction flow rate reaches stability. The driving power value corresponding to the minimum flow rate L_1 is the first power, which can be recorded as P_1. Figure 3 FIG. 1 is a flow chart of determining the corresponding relationship between flow and power according to an optional embodiment of the present invention. Figure 3 As shown in the figure, when you want to calibrate the correspondence between the actual flow rate and actual power of a diaphragm pump, you can first determine a flow rate to be calibrated, then drive the diaphragm pump to suck liquid, record the power of the diaphragm pump at this time as P_S, then measure the current suction flow rate, record it as L_C, compare L_C and L_S, if the two are equal, then the power value of the diaphragm pump corresponding to the flow rate to be calibrated L_S is P_S; if L_C and L_S are not equal, you can increase or decrease P_S and re-measure the suction flow rate until L_C and L_S are equal. Repeating the above process can establish a correspondence between the driving power range of the diaphragm pump and the flow range of the diaphragm pump (the range between the minimum flow rate and the maximum flow rate of the diaphragm pump).

[0040] Alternatively, the relationship K between the flow rate and power output of the diaphragm pump can be determined as follows: first, the flow output range of the diaphragm pump (the range between the minimum flow rate and the maximum flow rate of the diaphragm pump) is determined to be: L_1 to L_2, and the driving power range of the diaphragm pump is determined to be: P_1 to P_2, where the driving power value corresponding to the maximum flow rate L_2 is the second power, which can be recorded as P_2. Based on the linear relationship assumption, the relationship between the flow rate and power output can be determined as: Furthermore, when the diaphragm pump is actually used to perform a liquid suction operation, if the liquid suction operation requires a flow rate L′, it can be determined that the flow rate requirement can be met by adjusting the power output of the diaphragm pump to K*L′.

[0041] Step S104, obtain the operation parameters of the liquid absorption operation, wherein the operation parameters include: the range of the amount of liquid to be absorbed, the operation duration, and the threshold value of the residual liquid volume. The range of the amount of liquid to be absorbed can be determined according to the actual application requirements. For example, if the range of the amount of liquid that may be stored in the test tube to be absorbed in different experimental scenarios is 100μl to 800μl, then the range of the amount of liquid to be absorbed for this liquid absorption operation is 100μl to 800μl. The operation duration indicates that the liquid absorption operation is required to be completed within this time. The threshold value of the residual liquid volume indicates the maximum amount of liquid remaining in the test tube after the liquid absorption operation is completed. The operation parameters can be used to indicate the precise requirements of the operation.

[0042] Step S106 determines the actual power range for the liquid suction operation within the drive power range based on the operating parameters. Due to the operating parameters, the diaphragm pump cannot be used arbitrarily for liquid suction operations; otherwise, the required operation duration or residual liquid volume may not be met. Therefore, this step selects an actual power range within the drive power range that meets the operating parameters. If the diaphragm pump performs the liquid suction operation using power within this actual power range, the aforementioned operating parameters can be met.

[0043] As an optional embodiment, according to the operation parameters, the actual power range of the liquid absorption operation is determined within the driving power range, including: during the operation time, controlling the diaphragm pump to use a first power to absorb the first liquid in the test tube, and determining the residual amount of the first liquid in the test tube, wherein the liquid amount of the first liquid in the test tube is the minimum value in the absorption liquid amount range; when the residual amount of the first liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above-mentioned absorption of the first liquid operation until a third power is obtained, wherein when the diaphragm pump is controlled to use the third power to absorb the first liquid, the residual amount of the first liquid in the test tube is less than or equal to at a residual amount threshold; within the operation time, controlling the diaphragm pump to adopt a first power to absorb the second liquid in the test tube, and determining the residual amount of the second liquid in the test tube, wherein the amount of the second liquid in the test tube is the maximum value in the absorption amount range; when the residual amount of the second liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the second liquid until a fourth power is obtained, wherein when the diaphragm pump is controlled to adopt the fourth power to absorb the second liquid, the residual amount of the second liquid in the test tube is less than or equal to the residual amount threshold, and the fourth power is less than the second power; determining the actual power range according to the third power and the fourth power.

[0044] Figure 4 FIG. 1 is a flow chart of determining the third power based on the residual amount of liquid according to an optional embodiment of the present invention. Figure 4As shown, the liquid volume of the first liquid corresponding to the liquid suction operation is the minimum value in the suction liquid volume range, and the residual volume threshold of this time is set to C1. Then, the diaphragm pump can be driven to suck liquid with the power P_1 first. After the suction time reaches the operation time, the residual liquid volume in the test tube is weighed. If the residual liquid volume is greater than C1, it means that the suction force of the diaphragm pump is insufficient, and the suction power needs to be increased. The first liquid is refilled into the test tube, and then the first liquid is repeatedly sucked with the increased suction power and the residual liquid volume is weighed until the residual volume is less than C1. In the above process, it is necessary to pay attention to whether the suction power is greater than P_2. If it is greater than P_2, it means that the maximum power of the diaphragm pump cannot meet the suction requirements, and a diaphragm pump with a larger nominal power needs to be replaced.

[0045] Based on the above process, it is possible to determine that the minimum liquid suction volume V_1 corresponds to an output power range of P_3 to P_2, and that the maximum liquid suction volume V_2 corresponds to an output power range of P_4 to P_2, where P_3 represents the third power and P_4 represents the fourth power. The power output range of the diaphragm pump corresponding to the liquid suction volumes V_1 to V_2 is P_3 to P_4 (i.e., the range between the third power and the fourth power). In the above process, the output power range P_3 to P_2 corresponding to the minimum liquid suction volume V_1 indicates that when the output power of the diaphragm pump performing the liquid suction operation is within the range of P_3 to P_2, the residual liquid amount of the liquid after the minimum liquid suction volume V_1 is ensured to be less than the residual amount threshold C1. The output power range P_4 to P_2 corresponding to the maximum liquid suction volume V_2 indicates that when the output power of the diaphragm pump performing the liquid suction operation is within the range of P_4 to P_2, the residual liquid amount of the liquid after the maximum liquid suction volume V_2 is ensured to be less than the residual amount threshold C1. Therefore, for liquid with a volume within the range of V_1 to V_2, the diaphragm pump is used to perform a suction operation thereon and the power range of the diaphragm pump required to ensure the residual volume of the liquid is from the third power P_3 to the fourth power P_4.

[0046] As an optional embodiment, the determining the actual power range according to the third power P_3 and the fourth power P_4 can include the following process: in the case that the operation parameter of the liquid suction operation includes a magnetic bead loss rate threshold value, the diaphragm pump is controlled to suck the first liquid in the test tube by the fourth power P_4 within the operation time length, and the magnetic bead loss rate after the first liquid is sucked is determined; in the case that the magnetic bead loss rate after the first liquid is sucked is greater than the magnetic bead loss rate threshold value, the power of the diaphragm pump is gradually reduced and the above-mentioned operation of sucking the first liquid is repeated until the fifth power P_5 is obtained, wherein the magnetic bead loss rate after the diaphragm pump is controlled to suck the first liquid by the fifth power P_5 is less than or equal to the magnetic bead loss rate threshold value, and the fifth power P_5 is greater than or equal to the third power P_3; the diaphragm pump is controlled to suck the second liquid in the test tube by the fourth power P_4 within the operation time length, and the magnetic bead loss rate after the second liquid is sucked is determined; in the case that the magnetic bead loss rate after the second liquid is sucked is greater than the magnetic bead loss rate threshold value, the power of the diaphragm pump is gradually reduced and the above-mentioned operation of sucking the second liquid is repeated until the sixth power P_6 is obtained, wherein the magnetic bead loss rate after the diaphragm pump is controlled to suck the second liquid by the sixth power P_6 is less than or equal to the magnetic bead loss rate threshold value, and the sixth power P_6 is greater than the third power P_3; and the actual power range is determined according to the fifth power P_5 and the sixth power P_5 (that is, the actual power range is P_5 to P_6).

[0047] The optional embodiment provides a method for further refining the actual power range of the diaphragm pump according to the magnetic bead loss rate. In the magnetic separation process in the enzymatic chemiluminescence technology, if the liquid suction power of the diaphragm pump is too large, the magnetic bead loss rate may be too large, the magnetic beads may be lost too much, and the determination of the experimental value may be affected. Therefore, in the case that the operation parameter limits the threshold value of the magnetic bead loss rate, the available power range of the diaphragm pump can be further limited, the diaphragm pump power range meeting the requirements of the operation parameter in terms of both the liquid residual amount and the magnetic bead loss rate can be taken as the actual power range of the diaphragm pump, and the diaphragm pump can accurately complete the liquid suction operation based on the actual power range.

[0048] Figure 5 is a flowchart of determining the fifth power based on the liquid residual amount according to the optional embodiment of the present application, and the method can further accurately determine the power output of the diaphragm pump according to the magnetic bead loss rate, Figure 5 C_min in the formula represents the magnetic bead loss rate threshold value, and the power gradient value P_rate represents the power unit change amount when the power of the diaphragm pump is gradually reduced when it is found that the magnetic bead loss rate is greater than the magnetic bead loss rate threshold value. It can be understood that the method of determining the fifth power P_5 can also be used to determine the sixth power P_6.

[0049] Optionally, this step is tested with real magnetic beads. For the minimum aspirated liquid volume V_1 and the maximum aspirated liquid volume V_2 (for example, the aspirated liquid volume range is 100 μL to 800 μL), the following equation can be used: Figure 5 The method shown is used to measure the minimum liquid volume V_1 corresponding to the output power range P_3 to P_5; Figure 5 The same method can be used to determine the output power range P_3 to P_6 corresponding to the maximum liquid suction volume V_2; then the corresponding power output of the liquid suction flow rates V_1 to V_2 is P_5 to P_6 (the range between the fifth power and the sixth power).

[0050] Step S108 : determining a target buffer according to the driving power range of the diaphragm pump, wherein the target buffer is used to buffer the pulse fluctuation of the diaphragm pump; and setting the target buffer at the suction end of the diaphragm pump.

[0051] The target buffer can be called a buffer or a buffer block. A buffer is essentially a cavity that can be connected in series with a pipeline to stabilize the flow of a diaphragm pump. Optionally, the buffer block can be installed between the suction point and the diaphragm pump pipeline, close to the diaphragm pump to achieve the best pulse buffering effect.

[0052] The relationship between the volume of the buffer and flow stability is as follows: the larger the buffer volume, the more stable the diaphragm pump's flow; however, the suction response speed will be slower. The smaller the buffer volume, the faster the diaphragm pump's suction response, but the less stable the flow. Therefore, choosing a buffer is essentially choosing the buffer volume. There are generally two types of buffers: block-shaped buffers, with adjustable volume, such as cubes, rectangles, and spheres; and ring-shaped buffers, with adjustable ring length, essentially making the pipeline resemble a "spring." The buffer's buffer space is adjustable; the buffer can be cubed or rectangular, and in this case, a sliding block can be installed on the buffer, which can be moved according to the required buffer volume. Spherical buffers have a retractable block.

[0053] As an optional embodiment, the target buffer is determined according to the driving power range of the diaphragm pump, including: setting a first number of initial buffers at the suction end of the diaphragm pump, wherein the diameter of the initial buffer is the first diameter; while controlling the diaphragm pump to perform the suction operation using the minimum value in the driving power range, performing the following test: testing whether the liquid flow is smooth when the diaphragm pump absorbs liquid through the first number of initial buffers while gradually increasing the first number, until the liquid flow reaches a smooth state when the diaphragm pump absorbs liquid through the second number of initial buffers; subtracting a predetermined number from the second number to obtain a third number; testing whether the liquid flow is smooth when the diaphragm pump absorbs liquid through a third number of test buffers while gradually increasing the diameter of the test buffer, until the liquid flow reaches a smooth state when the diaphragm pump absorbs liquid through a third number of test buffers of the second diameter, wherein the initial value of the diameter of the test buffer is the first diameter; determining the target buffer, wherein the target buffer includes a third number of buffers with a diameter of the second diameter.

[0054] Alternatively, the predetermined number can be determined based on the size of the second number. When the second number is small, the predetermined number can be a smaller value, such as 1; when the second number is large, the predetermined number can be a larger value, such as multiplying the second number by a percentage to obtain the predetermined number. This approach is based on the fact that if the second number is large, it indicates that the volume of the single buffer equipped for the diaphragm pump is too small. The buffering effect of a smaller number does not meet the required performance, necessitating the connection of a larger number of buffers to achieve the desired buffering effect. Connecting too many buffers to the suction end of the diaphragm pump will result in excessive buffer length, affecting wiring layout and causing inconvenience at the test site. If the second number is small, subtracting a larger number from the predetermined number would require increasing the diameter of the remaining buffers to a very large size to meet the buffering requirements, which is obviously unreasonable. Therefore, as an alternative embodiment, the specific value of the predetermined number can be determined by setting a buffer number threshold: when the second number is not greater than the buffer number threshold, the predetermined number is set to 1; when the second number is greater than the buffer number threshold, the second number is multiplied by a percentage to obtain the predetermined number. In this way, a balance can be achieved between the number and diameter of the buffers to determine a reasonable buffer solution for the diaphragm pump.

[0055] As an optional implementation method, this solution provides a simple buffer block model and provides an adjustment solution based on this model. Figure 6 Schematic diagram of a method for screening a target buffer according to an optional embodiment of the present invention. Figure 6As shown, this solution can use a spiral series connection method, using multiple spiral tubes connected in series as the target buffer. First, obtain the parameters of the basic spiral tube J_l: diameter d_1, length l_1, and the volume of a single basic spiral tube V_1. Then, determine the iterative update parameter B, which represents the arithmetic resolution of the spiral tube diameter (which can be selected based on actual conditions).

[0056] Connect several basic spiral tubes J_1 in series to a pipeline. Use power P_1 to start a diaphragm pump to perform a suction test and observe whether the flow rate is smooth. If not, increase the number of basic spiral tubes in the pipeline by 1 each time and repeat the test until the flow rate in the pipeline reaches a smooth state. It should be noted that the standard for a smooth flow rate in the pipeline can be determined as follows: the liquid in the pipeline does not experience pulsation and the water flow in the pipeline can be maintained continuously.

[0057] At this point, the buffer selection scheme can be further optimized. If the flow in the pipeline reaches a steady state in the previous step, the number of basic spiral tubes at this time can be reduced by n (for example, by 1), and the number of spiral tubes at this time can be recorded as N1. Then, the diaphragm pump can be started with power P_1 to perform a liquid suction test to observe whether the pipeline flow reaches a steady state. If it does not reach a steady state, the diameter of the spiral tube can be increased by B. Repeat the above test until the pipeline flow reaches a steady state. The spiral tube diameter at this time is recorded as D. This can determine a set of optimal target buffer combinations, that is, using a buffer spiral tube with a number N1 and a diameter D as the target buffer.

[0058] At this point, V_X can represent the total volume of the final spiral tube, N1 represents the number of spiral tubes, l represents the length of the spiral tube, and D represents the diameter of the spiral tube. V_X = N1*π(D / 2) 2 *(N1*l_1); generally, the volume of the current spiral tube will not be larger than the volume of the number of basic spiral tubes plus 1, that is, n*V_1>(n-1)*V_X is guaranteed, where V_1 represents the volume of the basic spiral tube and n represents the second number.

[0059] Step S110 , controlling the diaphragm pump to perform a liquid suction operation using a target power within an actual power range.

[0060] Optionally, the target power can be determined as follows: Based on the minimum flow rate L_1 of the diaphragm pump, the first power P_1 corresponding to the minimum flow rate L_1, the maximum flow rate L_2 of the diaphragm pump, and the second power P_2 corresponding to the maximum flow rate L_2, the relationship between the flow rate of the diaphragm pump and the driving power output within the actual power range is determined as follows: The target power is determined as K*L' based on the liquid suction flow rate L' of the liquid suction operation, wherein the liquid suction flow rate L' of the liquid suction operation represents the liquid suction flow rate required for a specific operation in the liquid suction operation.

[0061] By the above steps, by acquiring the operation parameters of the liquid suction operation, and matching the actual working state of the diaphragm pump according to the operation parameters of the liquid suction operation, the purpose of controlling the diaphragm pump to accurately perform the liquid suction operation is achieved, thereby realizing the technical effect of providing a high-precision diaphragm pump scheme for the liquid suction operation, and further solving the technical problem of lacking a diaphragm pump scheme for performing a liquid suction operation with high precision in the related art.

[0062] Figure 7 is a flowchart of a liquid suction operation control method according to an optional embodiment of the present application, as shown in Figure 7 The liquid suction operation control method can include the following steps:

[0063] Step 1, the diaphragm pump can be determined according to the liquid target flow required by the liquid suction operation and the flow margin ratio, the maximum flow required by the liquid suction operation can be calculated first, i.e. the liquid target flow is calculated, and the diaphragm pump with a nominal flow greater than the maximum required flow A% margin is selected, i.e. the nominal flow of the diaphragm pump = liquid target flow*(1+A%).

[0064] Step 2, determine the driving power value P_1 corresponding to the minimum flow L_1 of the diaphragm pump, and determine the driving power value P_2 corresponding to the maximum flow L_2 of the diaphragm pump.

[0065] Step 3, determine the relationship K between the flow and the driving power output of the diaphragm pump, for example

[0066] Step 4, select a suitable target buffer and add the target buffer to the liquid suction pipeline to adjust the flow stability, the volume of the target buffer can be V_X=N1*π(D / 2) 2 *(N1*l_1).

[0067] Step 5, according to the liquid suction residual amount threshold C1 and the liquid suction range V_1 to V_2, determine the power output range of the diaphragm pump to be P_3 to P_4, so that the liquid amount in the test tube between V_1 to V_2 can be sucked by the power between P_3 to P_4, and the residual amount of the liquid after suction is less than the residual amount threshold C1;

[0068] Step 6, according to the magnetic bead loss rate requirement of the liquid suction operation, determine the actual power range P_5 to P_6 between the power output range P_3 to P_4 of the diaphragm pump, so that the magnetic bead loss rate of the test tube when the liquid suction operation is performed by the power between P_5 to P_6 can be not greater than the magnetic bead loss rate threshold;

[0069] Step 7: Control the diaphragm pump to use a power between P_5 and P_6 to perform the liquid suction operation.

[0070] The above optional implementation has the following advantages: by correcting the accuracy of the diaphragm pump, the actual output power of the diaphragm pump is determined according to the relationship between the real power and flow of the diaphragm pump, thereby improving the suction accuracy of the diaphragm pump; the buffer room is set according to the liquid suction speed of the diaphragm pump, and the size of the buffer room is adjusted to make the suction flow rate stable; when there are multiple suction components, the power value of each suction channel can be adjusted according to actual needs, so that the suction flow rate of each suction channel can be consistent, or the suction flow rates of different suction channels can be different, and the control is more precise.

[0071] It should be noted that for the aforementioned method embodiments, for simplicity of description, they are all expressed as a series of action combinations. However, those skilled in the art should be aware that the present invention is not limited by the order of the actions described, because according to the present invention, certain steps can be performed in other orders or simultaneously. Secondly, those skilled in the art should also be aware that the embodiments described in this specification are all preferred embodiments, and the actions and modules involved are not necessarily required by the present invention.

[0072] Through the description of the above embodiments, those skilled in the art can clearly understand that the control method for the diaphragm pump liquid suction according to the above embodiment can be implemented by means of software plus the necessary general hardware platform. Of course, it can also be implemented by hardware, but in many cases the former is a better implementation method. Based on this understanding, the technical solution of the present invention, or the part that contributes to the existing technology, can be embodied in the form of a software product. The computer software product is stored in a storage medium (such as ROM / RAM, magnetic disk, optical disk), and includes a number of instructions for enabling a terminal device (which can be a mobile phone, computer, server, or network device, etc.) to execute the methods of various embodiments of the present invention.

[0073] According to an embodiment of the present invention, there is also provided a liquid suction operation control device for implementing the above-mentioned diaphragm pump liquid suction control method. Figure 8 : is a structural block diagram of a liquid suction operation control device provided according to an embodiment of the present invention, such as Figure 8 As shown, the liquid suction operation control device includes: a first determination module 82, an acquisition module 84, a second determination module 86, a third determination module 88 and a control module 89. The liquid suction operation control device is described below.

[0074] The first determining module 82 is configured to determine a driving power range of a diaphragm pump used in the liquid suction operation according to a target liquid flow rate required for the liquid suction operation.

[0075] The acquisition module 84 is connected to the first determination module 82 and is used to acquire operation parameters of the liquid suction operation, wherein the operation parameters include: a suction liquid volume range, operation duration and a liquid residual volume threshold.

[0076] The second determining module 86 is connected to the obtaining module 84 and is used to determine an actual power range corresponding to the liquid suction operation within the driving power range according to the operation parameters.

[0077] a third determining module 88, connected to the second determining module 86, for determining a target buffer according to a driving power range of the diaphragm pump, and for setting the target buffer at the suction end of the diaphragm pump, wherein the target buffer is used to buffer pulse fluctuations of the diaphragm pump;

[0078] The control module 89 is connected to the third determining module 88 and is used to control the diaphragm pump to perform the liquid suction operation using the target power within the actual power range.

[0079] It should be noted here that the above-mentioned first determination module 82, acquisition module 84, second determination module 86, third determination module 88 and control module 89 correspond to steps S102 to S110 in the embodiment, and the instances and application scenarios implemented by multiple modules and corresponding steps are the same, but are not limited to the contents disclosed in the above-mentioned embodiments.

[0080] According to an embodiment of the present invention, a diaphragm pump liquid aspirating device is further provided for aspirating waste liquid from a test tube. Figure 9 Schematic diagram of a diaphragm pump liquid suction device according to an optional embodiment of the present invention. Figure 9 As shown, the liquid aspiration device may include: a diaphragm pump, a target buffer, a liquid aspiration needle, a one-way valve, and the aforementioned liquid aspiration operation control device, wherein the liquid aspiration needle is connected to the target buffer, the target buffer is connected to the liquid aspiration end of the diaphragm pump, the liquid discharge end of the diaphragm pump is connected to the one-way valve, and the diaphragm pump liquid aspiration control device is electrically connected to the diaphragm pump. The diaphragm pump liquid aspiration control device can be used to execute any of the aforementioned diaphragm pump liquid aspiration control methods to achieve measurement and control of the diaphragm pump, allowing the diaphragm pump to complete high-precision liquid aspiration operations.

[0081] Embodiments of the present invention may provide a computer device. Optionally, in this embodiment, the computer device may be located in at least one of multiple network devices in a computer network. The computer device includes a memory and a processor. The method embodiments provided in the embodiments of the present application may be executed in the computer device, which may include a mobile terminal, a computer terminal, or a similar computing device. Figure 10 The hardware structure block diagram of a computer terminal for implementing a control method for a diaphragm pump to suck liquid is shown. Figure 10As shown, the computer terminal 10 may include one or more processors (processors 12a, 12b, ..., 12n are shown in the figure) (the processor may include but is not limited to a microprocessor MCU or a programmable logic device FPGA and other processing devices), a memory 14 for storing data. In addition, it may also include: a display, an input / output interface (I / O interface), a universal serial bus (USB) port (which may be included as one of the ports of the BUS bus), a network interface, a power supply and / or a camera. It will be understood by those skilled in the art that Figure 10 The structure shown is only for illustration and does not limit the structure of the above electronic device. Figure 10 More or fewer components than shown, or with Figure 10 Different configurations shown.

[0082] It should be noted that the one or more processors and / or other data processing circuits described above may generally be referred to herein as "data processing circuitry." The data processing circuitry may be embodied in whole or in part as software, hardware, firmware, or any other combination thereof. Furthermore, the data processing circuitry may be a single, independent processing module, or may be incorporated in whole or in part into any of the other components of the computer terminal 10. As described in the embodiments of the present application, the data processing circuitry serves as a processor control (e.g., selection of a variable resistor terminal path connected to an interface).

[0083] The memory 14 can be used to store software programs and modules of application software, such as the program instructions / data storage device corresponding to the control method of the diaphragm pump suction in the embodiment of the present invention. The processor executes various functional applications and data processing by running the software programs and modules stored in the memory 14, that is, realizing the control method of the diaphragm pump suction of the above-mentioned application. The memory 14 may include a high-speed random access memory, and may also include a non-volatile memory, such as one or more magnetic storage devices, flash memory, or other non-volatile solid-state memory. In some instances, the memory 14 may further include a memory remotely located relative to the processor, and these remote memories may be connected to the computer terminal 10 via a network. Examples of the above-mentioned network include, but are not limited to, the Internet, an intranet, a local area network, a mobile communication network, and combinations thereof. The display may be, for example, a touch-screen liquid crystal display (LCD), which enables a user to interact with the user interface of the computer terminal 10.

[0084] Among them, the memory can be used to store software programs and modules, such as the program instructions / modules corresponding to the control method and device for diaphragm pump liquid suction in the embodiment of the present invention. The processor executes various functional applications and data processing by running the software programs and modules stored in the memory, that is, realizing the above-mentioned control method for diaphragm pump liquid suction. The memory may include a high-speed random access memory, and may also include a non-volatile memory, such as one or more magnetic storage devices, flash memory, or other non-volatile solid-state memory. In some instances, the memory may further include a memory remotely located relative to the processor, and these remote memories may be connected to the computer terminal via a network. Examples of the above-mentioned network include but are not limited to the Internet, corporate intranet, local area network, mobile communication network and combinations thereof.

[0085] The processor can call the information and application stored in the memory through the transmission device to perform the following steps: determine the driving power range of the diaphragm pump used in the liquid suction operation based on the liquid target flow required for the liquid suction operation; obtain the operating parameters of the liquid suction operation, wherein the operating parameters include: the suction liquid volume range, the operation time and the liquid residual volume threshold; determine the actual power range corresponding to the liquid suction operation within the driving power range based on the operating parameters; determine the target buffer based on the driving power range of the diaphragm pump, wherein the target buffer is used to buffer the pulse fluctuations of the diaphragm pump; set the target buffer at the suction end of the diaphragm pump; control the diaphragm pump to use the target power within the actual power range to perform the liquid suction operation.

[0086] Optionally, the processor may also execute the program code of the following steps: determining the driving power range of the diaphragm pump used in the liquid suction operation according to the target flow required for the liquid suction operation, including: determining the flow margin value according to the liquid target flow and flow margin ratio required for the liquid suction operation, wherein the flow margin ratio is greater than 1; determining the diaphragm pump according to the flow margin value, wherein the nominal flow of the diaphragm pump matches the flow margin value; measuring a first power corresponding to the minimum flow of the diaphragm pump; measuring a second power corresponding to the maximum flow of the diaphragm pump, wherein the second power is the floating lower limit of the nominal flow of the diaphragm pump; and determining the driving power range according to the first power and the second power.

[0087] Optionally, the processor may also execute the program code of the following steps: determining the actual power range of the liquid absorption operation within the driving power range according to the operation parameters, including: controlling the diaphragm pump to use a first power to absorb the first liquid in the test tube within the operation duration, and determining the residual amount of the first liquid in the test tube, wherein the amount of the first liquid in the test tube is the minimum value in the absorption liquid amount range; when the residual amount of the first liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the first liquid until a third power is obtained, wherein the residual amount of the first liquid in the test tube when the diaphragm pump is controlled to use the third power to absorb the first liquid is greater than the residual amount threshold. the residual amount is less than or equal to the residual amount threshold; during the operation time, the diaphragm pump is controlled to adopt a first power to absorb the second liquid in the test tube, and the residual amount of the second liquid in the test tube is determined, wherein the liquid amount of the second liquid in the test tube is the maximum value in the absorption liquid amount range; when the residual amount of the second liquid in the test tube is greater than the residual amount threshold, the power of the diaphragm pump is gradually increased and the above-mentioned operation of absorbing the second liquid is repeated until a fourth power is obtained, wherein when the diaphragm pump is controlled to adopt the fourth power to absorb the second liquid, the residual amount of the second liquid in the test tube is less than or equal to the residual amount threshold, and the fourth power is less than the second power; according to the third power and the fourth power, the actual power range is determined.

[0088] Optionally, the processor may also execute the program code of the following steps: determining the actual power range according to the third power and the fourth power, including: when the operating parameters of the liquid absorption operation include a magnetic bead loss rate threshold, controlling the diaphragm pump to use the fourth power to absorb the first liquid in the test tube within the operation time, and determining the magnetic bead loss rate after absorbing the first liquid; when the magnetic bead loss rate after absorbing the first liquid is greater than the magnetic bead loss rate threshold, gradually reducing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the first liquid until the fifth power is obtained, wherein the magnetic bead loss rate after controlling the diaphragm pump to use the fifth power to absorb the first liquid is greater than the magnetic bead loss rate threshold. The magnetic bead loss rate is less than or equal to the magnetic bead loss rate threshold, and the fifth power is greater than or equal to the third power; within the operation time, the diaphragm pump is controlled to use the fourth power to absorb the second liquid in the test tube, and the magnetic bead loss rate after absorbing the second liquid is determined; when the magnetic bead loss rate after absorbing the second liquid is greater than the magnetic bead loss rate threshold, the power of the diaphragm pump is gradually reduced and the above-mentioned operation of absorbing the second liquid is repeated until a sixth power is obtained, wherein the magnetic bead loss rate after controlling the diaphragm pump to use the sixth power to absorb the second liquid is less than or equal to the magnetic bead loss rate threshold, and the sixth power is greater than the third power; according to the fifth power and the sixth power, the actual power range is determined.

[0089] Optionally, the processor may also execute program code for the following steps: determining a target buffer according to the driving power range of the diaphragm pump, including: setting a first number of initial buffers at the suction end of the diaphragm pump, wherein the diameter of the initial buffer is the first diameter; performing the following test while controlling the diaphragm pump to perform suction operation using the minimum value in the driving power range: testing whether the liquid flow is smooth when the diaphragm pump absorbs liquid through the first number of initial buffers while gradually increasing the first number, until the liquid flow reaches a smooth state when the diaphragm pump absorbs liquid through the second number of initial buffers; subtracting a predetermined number from the second number to obtain a third number; testing whether the liquid flow is smooth when the diaphragm pump absorbs liquid through a third number of test buffers while gradually increasing the diameter of the test buffer, until the liquid flow reaches a smooth state when the diaphragm pump absorbs liquid through a third number of test buffers of the second diameter, wherein the initial value of the diameter of the test buffer is the first diameter; determining the target buffer, wherein the target buffer includes a third number of buffers with a diameter of the second diameter.

[0090] Optionally, the processor may further execute the program code of the following steps: according to the minimum flow rate L_1 of the diaphragm pump, the first power P_1 corresponding to the minimum flow rate L_1, the maximum flow rate L_2 of the diaphragm pump, and the second power P_2 corresponding to the maximum flow rate L_2, determine the relationship between the flow rate and the driving power output of the diaphragm pump within the actual power range as follows: According to the liquid suction flow rate L' of the liquid suction operation, the target power is determined to be K*L'.

[0091] A person skilled in the art will understand that all or part of the steps in the various methods of the above embodiments can be completed by instructing the hardware related to the terminal device through a program, and the program can be stored in a non-volatile storage medium, which may include: a flash drive, a read-only memory (ROM), a random access memory (RAM), a magnetic disk or an optical disk, etc.

[0092] The embodiment of the present invention further provides a non-volatile storage medium. Optionally, in this embodiment, the non-volatile storage medium can be used to store the program code executed by the control method for the diaphragm pump liquid aspiration provided by the above embodiment.

[0093] Optionally, in this embodiment, the non-volatile storage medium may be located in any computer terminal in a computer terminal group in a computer network, or in any mobile terminal in a mobile terminal group.

[0094] Optionally, in this embodiment, the non-volatile storage medium is configured to store program code for executing the following steps: determining a driving power range of the diaphragm pump used in the liquid suction operation based on a target liquid flow rate required for the liquid suction operation; obtaining operation parameters of the liquid suction operation, wherein the operation parameters include: a suction liquid volume range, an operation duration, and a liquid residual volume threshold; determining an actual power range corresponding to the liquid suction operation within the driving power range based on the operation parameters; determining a target buffer based on the driving power range of the diaphragm pump, wherein the target buffer is used to buffer the pulse fluctuations of the diaphragm pump; setting the target buffer at the suction end of the diaphragm pump; and controlling the diaphragm pump to perform the liquid suction operation using a target power within the actual power range.

[0095] Optionally, in this embodiment, the non-volatile storage medium is configured to store program code for executing the following steps: determining a driving power range of a diaphragm pump used in the liquid suction operation based on a target flow rate required for the liquid suction operation, including: determining a flow margin value based on the liquid target flow rate and a flow margin ratio required for the liquid suction operation, wherein the flow margin ratio is greater than 1; determining the diaphragm pump based on the flow margin value, wherein the nominal flow rate of the diaphragm pump matches the flow margin value; measuring a first power corresponding to the minimum flow rate of the diaphragm pump; measuring a second power corresponding to the maximum flow rate of the diaphragm pump, wherein the second power is a floating lower limit of the nominal flow rate of the diaphragm pump; and determining a driving power range based on the first power and the second power.

[0096] Optionally, in this embodiment, the non-volatile storage medium is configured to store program code for executing the following steps: determining an actual power range of the liquid absorption operation within a driving power range based on the operation parameters, including: controlling the diaphragm pump to use a first power to absorb the first liquid in the test tube within the operation duration, and determining the residual amount of the first liquid in the test tube, wherein the amount of the first liquid in the test tube is the minimum value in the absorption liquid amount range; when the residual amount of the first liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the first liquid until a third power is obtained, wherein when the diaphragm pump is controlled to use the third power to absorb the first liquid, the first The residual amount of liquid in the test tube is less than or equal to the residual amount threshold; during the operation time, the diaphragm pump is controlled to use the first power to absorb the second liquid in the test tube, and the residual amount of the second liquid in the test tube is determined, wherein the liquid amount of the second liquid in the test tube is the maximum value in the absorbed liquid amount range; when the residual amount of the second liquid in the test tube is greater than the residual amount threshold, the power of the diaphragm pump is gradually increased and the above-mentioned operation of absorbing the second liquid is repeated until a fourth power is obtained, wherein when the diaphragm pump is controlled to use the fourth power to absorb the second liquid, the residual amount of the second liquid in the test tube is less than or equal to the residual amount threshold, and the fourth power is less than the second power; based on the third power and the fourth power, the actual power range is determined.

[0097] Optionally, in this embodiment, the non-volatile storage medium is configured to store program codes for executing the following steps: determining an actual power range based on the third power and the fourth power, including: in a case where the operating parameters of the liquid absorption operation include a magnetic bead loss rate threshold, controlling the diaphragm pump to use the fourth power to absorb the first liquid in the test tube within the operation time, and determining the magnetic bead loss rate after absorbing the first liquid; in a case where the magnetic bead loss rate after absorbing the first liquid is greater than the magnetic bead loss rate threshold, gradually reducing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the first liquid until a fifth power is obtained, wherein, when the diaphragm pump is controlled to use the fifth power to absorb the first liquid, the magnetic bead loss rate is determined. The magnetic bead loss rate after the liquid is less than or equal to the magnetic bead loss rate threshold, and the fifth power is greater than or equal to the third power; within the operation time, the diaphragm pump is controlled to use the fourth power to absorb the second liquid in the test tube, and the magnetic bead loss rate after absorbing the second liquid is determined; when the magnetic bead loss rate after absorbing the second liquid is greater than the magnetic bead loss rate threshold, the power of the diaphragm pump is gradually reduced and the above-mentioned operation of absorbing the second liquid is repeated until the sixth power is obtained, wherein the magnetic bead loss rate after the diaphragm pump is controlled to use the sixth power to absorb the second liquid is less than or equal to the magnetic bead loss rate threshold, and the sixth power is greater than the third power; according to the fifth power and the sixth power, the actual power range is determined.

[0098] Optionally, in this embodiment, the non-volatile storage medium is configured to store program code for executing the following steps: determining a target buffer according to the driving power range of the diaphragm pump, including: setting a first number of initial buffers at the suction end of the diaphragm pump, wherein the diameter of the initial buffer is the first diameter; performing the following test while controlling the diaphragm pump to perform a suction operation using the minimum value in the driving power range: testing whether the liquid flow is smooth when the diaphragm pump absorbs liquid through the first number of initial buffers while gradually increasing the first number, until the liquid flow reaches a smooth state when the diaphragm pump absorbs liquid through the second number of initial buffers; subtracting a predetermined number from the second number to obtain a third number; testing whether the liquid flow is smooth when the diaphragm pump absorbs liquid through a third number of test buffers while gradually increasing the diameter of the test buffer, until the liquid flow reaches a smooth state when the diaphragm pump absorbs liquid through a third number of test buffers of the second diameter, wherein the initial value of the diameter of the test buffer is the first diameter; determining a target buffer, wherein the target buffer includes a third number of buffers with a diameter of the second diameter.

[0099] Optionally, in this embodiment, the non-volatile storage medium is configured to store program code for executing the following steps: according to the minimum flow rate L_1 of the diaphragm pump, the first power P_1 corresponding to the minimum flow rate L_1, the maximum flow rate L_2 of the diaphragm pump, and the second power P_2 corresponding to the maximum flow rate L_2, determining the relationship between the flow rate and the driving power output of the diaphragm pump within the actual power range as follows: According to the liquid suction flow rate L' of the liquid suction operation, the target power is determined to be K*L'.

[0100] The serial numbers of the above embodiments of the present invention are for description only and do not represent the advantages or disadvantages of the embodiments.

[0101] In the above embodiments of the present invention, the description of each embodiment has its own focus. For parts that are not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0102] In the several embodiments provided in this application, it should be understood that the disclosed technical content can be implemented in other ways. Among them, the device embodiments described above are only exemplary. For example, the division of units can be a logical function division. In actual implementation, there may be other division methods, such as multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point is that the mutual coupling or direct coupling or communication connection shown or discussed can be through some interfaces, indirect coupling or communication connection of units or modules, which can be electrical or other forms.

[0103] Units described as separate components may or may not be physically separate, and components shown as units may or may not be physical units, that is, they may be located in one place or distributed across multiple units. Some or all of the units may be selected to achieve the purpose of the present embodiment according to actual needs.

[0104] In addition, the functional units in the various embodiments of the present invention may be integrated into a single processing unit, each unit may exist physically separately, or two or more units may be integrated into a single unit. The aforementioned integrated units may be implemented in the form of hardware or software functional units.

[0105] If the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a non-volatile storage medium. Based on this understanding, the technical solution of the present invention, or the part that contributes to the prior art, or all or part of the technical solution can be embodied in the form of a software product. The computer software product is stored in a storage medium and includes several instructions for enabling a computer device (which can be a personal computer, server or network device, etc.) to execute all or part of the steps of the various embodiments of the present invention. The aforementioned storage medium includes: U disk, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), mobile hard disk, magnetic disk or optical disk, and other media that can store program codes.

[0106] The above are only preferred embodiments of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A method for controlling liquid suction by a diaphragm pump, characterized in that: include: Determining a driving power range of a diaphragm pump used in the liquid suction operation according to a target liquid flow rate required for the liquid suction operation; Acquiring operation parameters of the liquid suction operation, wherein the operation parameters include: a suction liquid volume range, an operation duration, and a liquid residual volume threshold; Determining an actual power range corresponding to the liquid suction operation within the driving power range according to the operation parameters; A target buffer is determined based on the driving power range of the diaphragm pump, wherein the target buffer is used to buffer the pulse fluctuations of the diaphragm pump; the target buffer is set at the suction end of the diaphragm pump; and the diaphragm pump is controlled to use the target power within the actual power range to perform the liquid suction operation.

2. The method according to claim 1, characterized in that The driving power range of the diaphragm pump used in the liquid suction operation is determined based on the target flow rate required for the liquid suction operation, including: determining a flow margin value according to a target liquid flow rate and a flow margin ratio required for the liquid suction operation, wherein the flow margin ratio is greater than 1; determining the diaphragm pump according to the flow margin value, wherein the nominal flow of the diaphragm pump matches the flow margin value; measuring a first power corresponding to a minimum flow rate of the diaphragm pump; measuring a second power corresponding to the maximum flow rate of the diaphragm pump, wherein the second power is a floating lower limit of the nominal flow rate of the diaphragm pump; The driving power range is determined according to the first power and the second power.

3. The method according to claim 2, characterized in that Determining an actual power range of the liquid suction operation within the driving power range according to the operation parameters includes: During the operation time, controlling the diaphragm pump to use the first power to absorb the first liquid in the test tube, and determining the residual amount of the first liquid in the test tube, wherein the amount of the first liquid in the test tube is a minimum value in the absorption amount range; When the residual amount of the first liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above-mentioned operation of sucking the first liquid until a third power is obtained, wherein when the diaphragm pump is controlled to suck the first liquid at the third power, the residual amount of the first liquid in the test tube is less than or equal to the residual amount threshold; During the operation time, controlling the diaphragm pump to use the first power to absorb the second liquid in the test tube, and determining the residual amount of the second liquid in the test tube, wherein the amount of the second liquid in the test tube is a maximum value in the absorption amount range; When the residual amount of the second liquid in the test tube is greater than the residual amount threshold, gradually increasing the power of the diaphragm pump and repeating the above-mentioned operation of sucking the second liquid until a fourth power is obtained, wherein when the diaphragm pump is controlled to suck the second liquid at the fourth power, the residual amount of the second liquid in the test tube is less than or equal to the residual amount threshold, and the fourth power is less than the second power; The actual power range is determined according to the third power and the fourth power.

4. The method according to claim 3, characterized in that The determining the actual power range according to the third power and the fourth power includes: When the operation parameters of the liquid aspiration operation include a magnetic bead loss rate threshold, During the operation time, controlling the diaphragm pump to use the fourth power to absorb the first liquid in the test tube, and determining a loss rate of magnetic beads after the first liquid is absorbed; When the magnetic bead loss rate after absorbing the first liquid is greater than the magnetic bead loss rate threshold, gradually reducing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the first liquid until a fifth power is obtained, wherein the magnetic bead loss rate after controlling the diaphragm pump to absorb the first liquid with the fifth power is less than or equal to the magnetic bead loss rate threshold, and the fifth power is greater than or equal to the third power; During the operation time, controlling the diaphragm pump to use the fourth power to absorb the second liquid in the test tube, and determining a loss rate of magnetic beads after the second liquid is absorbed; When the magnetic bead loss rate after absorbing the second liquid is greater than the magnetic bead loss rate threshold, gradually reducing the power of the diaphragm pump and repeating the above-mentioned operation of absorbing the second liquid until a sixth power is obtained, wherein the magnetic bead loss rate after controlling the diaphragm pump to absorb the second liquid with the sixth power is less than or equal to the magnetic bead loss rate threshold, and the sixth power is greater than the third power; The actual power range is determined according to the fifth power and the sixth power.

5. The method according to claim 1, wherein Determining a target buffer according to the driving power range of the diaphragm pump includes: Disposing a first number of initial buffers at the suction end of the diaphragm pump, wherein the diameter of the initial buffers is a first diameter; When the diaphragm pump is controlled to perform a liquid suction operation at the minimum value in the driving power range, the following test is performed: testing whether the liquid flow rate is smooth when the diaphragm pump draws liquid through the first number of initial buffers while gradually increasing the first number, until the liquid flow rate reaches smooth when the diaphragm pump draws liquid through the second number of initial buffers; subtracting a predetermined number from the second quantity to obtain a third quantity; testing whether the liquid flow rate is smooth when the diaphragm pump draws liquid through a third number of test buffers while gradually increasing the diameter of the test buffers, until the liquid flow rate reaches a smooth state when the diaphragm pump draws liquid through a third number of test buffers having the second diameter, wherein an initial value of the diameter of the test buffer is the first diameter; The target buffer is determined, wherein the target buffer includes the third number of buffers having the second diameter.

6. The method according to claim 1, characterized in that Also includes: According to the minimum flow rate L_1 of the diaphragm pump, the first power P_1 corresponding to the minimum flow rate L_1, the maximum flow rate L_2 of the diaphragm pump and the second power P_2 corresponding to the maximum flow rate L_2, the relationship between the flow rate and the driving power output of the diaphragm pump within the actual power range is determined as follows: According to the liquid suction flow rate L' of the liquid suction operation, the target power is determined to be K*L'.

7. A diaphragm pump liquid suction control device, characterized in that: include: A first determining module is configured to determine a driving power range of a diaphragm pump used in the liquid suction operation according to a target liquid flow rate required for the liquid suction operation; An acquisition module, configured to acquire operation parameters of the liquid aspirating operation, wherein the operation parameters include: a liquid aspirating volume range, an operation duration, and a liquid residual volume threshold; a second determining module, configured to determine an actual power range corresponding to the liquid suction operation within the driving power range according to the operation parameters; a third determining module, configured to determine a target buffer according to a driving power range of the diaphragm pump, and to set the target buffer at a suction end of the diaphragm pump, wherein the target buffer is used to buffer pulse fluctuations of the diaphragm pump; A control module is used to control the diaphragm pump to perform the liquid suction operation using a target power within the actual power range.

8. A diaphragm pump liquid suction device, characterized in that: include: A diaphragm pump, a target buffer, a liquid suction needle, a one-way valve and a diaphragm pump liquid suction control device according to claim 7, wherein the liquid suction needle is connected to the target buffer, the target buffer is connected to the liquid suction end of the diaphragm pump, the liquid discharge end of the diaphragm pump is connected to the one-way valve, and the diaphragm pump liquid suction control device is electrically connected to the diaphragm pump.

9. A non-volatile storage medium, characterized in that: The non-volatile storage medium includes a stored program, wherein when the program is running, the device where the non-volatile storage medium is located is controlled to execute the control method for diaphragm pump liquid suction according to any one of claims 1 to 6.

10. A computer device, characterized in that: The computer device includes a memory and a processor, the memory is used to store programs, and the processor is used to run the programs stored in the memory, wherein the control method for diaphragm pump liquid suction according to any one of claims 1 to 6 is executed when the program is run.

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