Continuously variable diameter flow control valve for simulating vascular peripheral resistance

Abstract

The present invention relates to a flow regulating valve with a continuously variable diameter for simulating peripheral resistance of blood vessels, comprising an upper valve body, blades, and a lower base plate; a circle of multiple first-level guide columns is provided at the lower part of the upper valve body; the number of blades is the same as the first-level guide columns; a first-level guide groove adapted to the first-level guide column is provided at the upper part of each blade, so that: the first-level guide column is limited to be located in the first-level guide groove and can change its relative position in the first-level guide groove; a second-level guide column is provided at the lower part of each blade; a plurality of second-level guide grooves, the same number as the blades, are provided at the upper part of the lower base plate, so that: the second-level guide column is limited to be located in the second-level guide groove and can change its relative position in the second-level guide groove; by rotating the upper valve body, force is applied to the first-level guide groove through the first-level guide column, and while changing the relative position of the first-level guide column in the first-level guide groove, the blade is forced to slide along the second-level guide groove, thereby realizing adjustment of the diameter of the central through hole.

Description

Technical Field

[0001] The invention relates to a flow regulating valve with a continuously variable diameter for simulating vascular peripheral resistance, and belongs to the technical field of metering design. Background Art

[0002] Oscillometric electronic blood pressure monitors are easy to use, unaffected by human factors, and offer relatively good repeatability, making them increasingly widely used. Currently, metrology institutions often use non-invasive blood pressure simulators to test the accuracy of electronic blood pressure monitors. However, the envelope curves set within these simulators are based on statistically empirical values, which only allow for repeatable measurements of electronic blood pressure monitors, but cannot provide traceability of the accuracy of dynamic blood pressure measurements.

[0003] The bionic human cardiovascular system is an important vehicle for medical research, and the simulation of peripheral vascular resistance is a key element. However, when using an oscillometric electronic blood pressure monitor dynamic traceability device that simulates the human heart and vascular system for testing, existing technology struggles to simulate the regulation of vascular pressure. Summary of the Invention

[0004] In order to simulate the peripheral resistance of bionic blood vessels, the present invention provides a continuously adjustable flow valve. By installing the regulating valve in the pipeline (simulated blood vessel), the diameter of the simulated blood vessel pathway can be changed to adjust the blood flow, thereby achieving the purpose of changing the peripheral resistance of the bionic blood vessels.

[0005] The present invention adopts the following technical solutions:

[0006] A continuously variable diameter flow regulating valve for simulating vascular peripheral resistance, comprising an upper valve body 2, blades 3, and a lower base plate 4; a circle of multiple primary guide posts 2a is provided at the lower portion of the upper valve body 2; the number of blades 3 is the same as the number of primary guide posts 2a; a primary guide groove 3a is provided on the upper portion of each blade 3 to match the primary guide post 2a, so that: the primary guide post 2a is limited in the primary guide groove 3a and can change its relative position in the primary guide groove 3a; a secondary guide post 3b is provided at the lower portion of each blade 3; the lower base plate The upper portion of the valve body 2 is provided with a plurality of secondary guide grooves 4a, the same number as the blades 3, so that: the secondary guide posts 3b are confined within the secondary guide grooves 4a and can change their relative positions within the secondary guide grooves 4a; the number of blades 3 is an even number, two of which are centrally symmetrical, and there are at least four of them; by rotating the upper valve body 2, the primary guide posts 2a apply force to the primary guide grooves 3a, changing the relative positions of the primary guide posts 2a within the primary guide grooves 3a, and forcing the blades 3 to slide along the secondary guide grooves 4a, thereby adjusting the diameter of the central through hole.

[0007] Preferably, the plurality of secondary guide grooves 4 a are circumscribed in a circle, and adjacent secondary guide grooves 4 a have the same included angle.

[0008] Furthermore, the plurality of primary guide grooves 3 a are arranged radially, or circumscribed to another circle, and the angles between adjacent primary guide grooves 3 a are the same.

[0009] Preferably, two hose quick connectors 1 are further included, which are respectively installed on the upper end of the upper valve body 2 and the lower end of the lower base 4.

[0010] Preferably, a scale is provided around the upper valve body 2.

[0011] Furthermore, the hose quick connector 1 is connected to the upper valve body 2 via a standard thread.

[0012] Furthermore, a sealing structure is provided at the junction of adjacent blades 3 .

[0013] Furthermore, the slots of the scale 6 are symmetrically distributed on the upper valve body 2 .

[0014] A dynamic tracing device for an oscillometric electronic sphygmomanometer employs the aforementioned flow control valve and includes a simulated blood tank 1 and a bionic simulation device. The bionic simulation device includes a blood supply pump 11, a constant-temperature simulated blood tank 9, a simulated heart 10, a stepping motor 12, a simulated aorta 8, and simulated radial and ulnar arteries 4. The suction end of the blood supply pump 11 extends into the simulated blood tank 1, and the output end is connected to the constant-temperature simulated blood tank 9. The constant-temperature simulated blood tank 9 is connected to the simulated heart 10. The simulated heart 10 is a piston cavity, the open end of which is connected to the stepping motor 12, which can stepwise control the piston's movement. The closed end of the piston cavity is connected to the simulated aorta 8, which is connected to the simulated radial and ulnar arteries 4. A first flow control valve 2 is provided at the front end of the simulated radial and ulnar arteries 4 and extends to the simulated blood tank 1. Dynamic pressure sensors 5 are built into both the simulated aorta 8 and the simulated radial and ulnar arteries 4. The flow control valve is mounted on at least one of the simulated aorta 8 and the simulated radial and ulnar arteries 4.

[0015] Preferably, it further comprises a simulated arm skeleton 3 having a hinge portion, and the connecting portion between the simulated aorta 8 and the simulated radial and ulnar arteries 4 corresponds to the hinge portion.

[0016] The beneficial effects of the present invention are:

[0017] For flow control valves:

[0018] 1) Both ends of the hose quick connector can be replaced according to different simulated vascular tubing systems, with good versatility and adaptability;

[0019] 2) Continuous adjustment of the diameter of bionic vascular conduits can be achieved, enabling simulation of more complex changes in peripheral resistance;

[0020] 3) Integrated scale enables precise adjustment of flow hole diameter, and symmetrical design enables easy reading of scale data under various installation conditions.

[0021] Dynamic traceability device for oscillometric electronic sphygmomanometers:

[0022] 5) Establish a relatively complete upper limb arterial vascular system, with parameters such as length, diameter, elastic modulus, and thickness close to those of the human body. Using bionic arteries and bionic blood mixed with saline and glycerol, the system achieves physical parameters similar to those of real blood, such as density. The overall characteristics of the developed device are close to those of a normal human physiological system, better meeting the requirements of a sphygmomanometer for measuring real human brachial artery blood pressure.

[0023] 6) The actual values ​​of brachial artery systolic and diastolic pressure are read by the implanted dynamic pressure sensor. The average value of systolic and diastolic pressure over several cycles after the system stabilizes is used as the standard value. The error is compared with the average value of several results detected by the sphygmomanometer. This method not only conforms to the measurement method of the sphygmomanometer detecting the real human body and judging the internal blood pressure of the human brachial artery by the blood pressure count value, but also can directly obtain the actual brachial artery blood pressure value at the cuff detection point, realizing direct dynamic traceability of the sphygmomanometer;

[0024] 7) The innovatively developed flow control valve and simulated heart model can change the peripheral resistance of the arterial system by adjusting the value of the flow control valve. By adjusting parameters such as blood viscosity, cardiac output and heart rate, it can achieve the control and simulation of single variables such as hyperlipidemia and heart rate, solving the experimental research on the influence of single factors that cannot be completed in medical clinical trials. It can carry out the degree and trend of the single influence of factors such as vascular pore size, vascular hardness, blood viscosity, blood density, heart rate, cardiac output, and peripheral vascular resistance on human blood pressure, providing a reliable research foundation for precision medicine and has high medical research value.

[0025] 8) Through the simulation of human blood pressure and the dynamic tracing of the electronic sphygmomanometer by this device, rich experimental data can be provided for the further improvement of the electronic sphygmomanometer in non-invasive blood pressure measurement of the human body. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is an exploded perspective view of a flow control valve with a continuously variable diameter (hereinafter referred to as "flow control valve") for simulating peripheral vascular resistance according to the present invention.

[0027] Figure 2 yes Figure 1 A perspective view from above.

[0028] Figure 3 It is a schematic diagram of the process of the flow control valve from fully open to fully closed.

[0029] Figure 4 It is a schematic diagram of the fluid path of the flow control valve.

[0030] Figure 5 This is a schematic diagram of the upper valve body and blades assembled together in a flow control valve.

[0031] Figure 6 This is a schematic diagram of the lower base and blades assembled together in a flow control valve.

[0032] Figure 7 It is a schematic cross-sectional view of the central axis of the flow control valve.

[0033] Figure 8 It is an exploded diagram of the flow control valve.

[0034] Figure 9 This is an exploded diagram of the flow control valve components after they are flipped 180°.

[0035] Figure 10 This is a detailed display of the components in the flow control valve.

[0036] Figure 11 This is a schematic diagram of a dynamic traceability device for an oscillometric electronic sphygmomanometer equipped with the aforementioned flow control valve.

[0037] Figure 12 This is another schematic diagram of the dynamic traceability device of the oscillometric electronic sphygmomanometer equipped with the above-mentioned flow regulating valve.

[0038] In Figures 1-10, 1. Hose quick connector, 2. Upper valve body, 3. Blade, 4. Lower base, 6. Scale, 2a. Primary guide post, 3a. Primary guide groove, 3b. Secondary guide post, 4a. Secondary guide groove;

[0039] Figure 11-12 In the figure, A1. Simulated blood liquid tank, A2. First flow regulating valve, A3. Simulated arm skeleton, A4. Ulnar artery, radial artery (with one-way valve), A5. Dynamic pressure sensor, A6. Brachial artery (with one-way valve), A7. Ascending aorta (with one-way valve), A8. Aortic arch, brachiocephalic artery, carotid artery (all with one-way valve), A9. Warm simulated blood box, A10. Simulated heart, A11. Blood supply pump, A12. Cuff, A13. Blood pressure monitor to be measured. DETAILED DESCRIPTION

[0040] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0041] See also Figures 1-10, a flow control valve with a continuously variable diameter for simulating vascular peripheral resistance, comprising an upper valve body 2, a blade 3, and a lower base plate 4; the lower portion of the upper valve body 2 is provided with a circle of multiple primary guide posts 2a; the number of the blades 3 is the same as the number of the primary guide posts 2a; the upper portion of each blade 3 is provided with a primary guide groove 3a adapted to the primary guide post 2a, so that: the primary guide post 2a is limited to being located in the primary guide groove 3a and the relative position in the primary guide groove 3a can be changed; the lower portion of each blade 3 is provided with a secondary guide post 3b; the upper portion of the lower base plate 4 is provided with a plurality of secondary guide grooves 4a, the same number as the number of the blades 3, so that: the secondary guide post 3b is limited to being located in the secondary guide groove 4a and the relative position in the secondary guide groove 4a can be changed; the number of the blades 3 is an even number, two of which are centrally symmetrical, and there are at least 4 (8 in this embodiment, such as Figure 8 By rotating the upper valve body 2, a force is applied to the primary guide groove 3a through the primary guide column 2a, changing the relative position of the primary guide column 2a in the primary guide groove 3a, and forcing the blade 3 to slide along the secondary guide groove 4a to achieve adjustment of the diameter of the central through hole.

[0042] In this embodiment, see Figure 8 , the multiple secondary guide grooves 4a are circumscribed in a circle, and the angles between adjacent secondary guide grooves 4a are the same.

[0043] In this embodiment, see Figure 8 The plurality of primary guide grooves 3a are arranged radially, or circumscribed to another circle, and the angles between adjacent primary guide grooves 3a are the same.

[0044] In this embodiment, see Figure 1 and 8 , and also includes two hose quick connectors 1, which are respectively installed on the upper end of the upper valve body 2 and the lower end of the lower base 4.

[0045] In this embodiment, a scale is provided around the upper valve body 2 , and the slots of the scale 6 are symmetrically distributed on the upper valve body 2 . The accompanying drawings do not specifically show the scale.

[0046] In this embodiment, see Figure 1 , the hose quick connector 1 is connected to the upper valve body 2 through a standard thread.

[0047] In this embodiment, a sealing structure, such as a sealing film, is provided at the joints of adjacent blades 3 .

[0048] Working principle:

[0049] The hose quick connector 1 is connected to the upper valve body 2 and the blade 3 through a standard thread. The standard thread can be changed according to actual needs. The quick connector size of the hose quick connector 1 can also be changed according to actual needs. The sizes in the design drawings are for reference only.

[0050] The upper valve body 2, blade 3, and lower base plate 4 are assembled in a sandwich structure. The primary guide groove 3a on the blade 3 is connected to the primary guide post 2a on the upper valve body 2, and the secondary guide post 3b on the blade 3 is connected to the secondary guide groove 4a on the lower base plate 4. By rotating the upper valve body 2, the blade 3 can slide in the primary guide groove 3a to adjust the diameter of the central through hole.

[0051] The number of blades 3 is consistent with the number of guide columns and grooves on the upper valve body 2 and the lower base plate 4. By increasing the number of blades 3, the shape of the central through hole can be made closer to a circle, which helps to control the pipe diameter more accurately (the number of valve body blades can be designed according to actual needs, and the number of blades in the figure is for reference only).

[0052] The joints between blades 3 should be sealed with sealing rings or other seals to prevent leakage of liquid in the pipeline. The slots of scale 6 are symmetrically distributed on the upper valve body 2, ensuring accurate readings under various installation conditions. By adjusting the outer diameters of the upper valve body 2 and the lower base plate 4, the minimum scale reading can be enlarged, improving adjustment accuracy. (The number of slots and valve body size can be adjusted according to actual needs; the design shown in the figure is for reference only.)

[0053] The rotary blade design of this flow control valve can continuously adjust the diameter of the central pipeline to achieve the purpose of quantitatively regulating the bionic blood flow, thereby realizing quantitative simulation of the size of the peripheral resistance; the circumferentially placed scale can amplify the minimum scale of the reading by adjusting the outer diameter of the valve body to achieve more precise flow regulation; the symmetrically designed scale can ensure that the valve body is easy to read and operate in various installation conditions; the standard threaded detachable quick connector design at both ends of the valve body enables the valve body to meet a wider range of installation conditions.

[0054] Figure 11 and 12 The schematic diagrams show the principle of the oscillometric sphygmomanometer dynamic traceability device from two different perspectives. Based on the upper limb vascular system, the main vessels of the relatively complete upper limb arterial system are used, including the ascending aorta, aortic arch, brachiocephalic artery, carotid artery, right subclavian artery, brachial artery, ulnar artery, and radial artery. All arterial branches are equipped with one-way valves to prevent blood backflow.

[0055] Figure 11 The middle bid number 3 is the upper and lower arm skeleton of the simulated arm, which is made of corresponding metal materials. It not only ensures sufficient strength to ensure the positional stability of the simulated arm and its muscle tissue and blood vessels, but also makes its overall mass and stiffness close to the parameters of a normal human arm.

[0056] The lower arm of the simulated arm is horizontal, with an angle of approximately 20-30° between the upper and lower arms to maintain consistency with blood pressure monitor measurements. The upper and lower arms are hinged, allowing for adjustment of their angles. The aortic arch and carotid artery branches are retained to facilitate blood flow diversion and prevent a sudden increase in brachial artery blood pressure when the cuff completely blocks the brachial artery. This design better aligns with human physiology and actual blood pressure monitor measurements.

[0057] like Figure 11-12 As shown, the simulated heart A10 is a piston chamber controlled by a stepper motor A12 at the bottom. Stepper motor A12 is computer-controlled, allowing preset piston stroke and frequency. Bionic blood is mixed with saline and glycerol. Blood in the bionic blood tank A1 is delivered by a blood pump A11 to a constant-temperature bionic blood tank A9 at the top, which maintains the bionic blood within a temperature range of (36.5±1)°C (normal human blood temperature is approximately 36.5°C). As the piston descends, blood enters the simulated heart A10 through a channel equipped with a one-way valve and bursts into the ascending aorta. Some blood enters the aortic arch and carotid aorta, passing through a second flow control valve A13 before returning to the constant-temperature tank. The majority of blood enters the brachial artery, where it is divided at the elbow into the ulnar and radial arteries. It then passes through first flow control valves A2 in these arteries before returning to the bionic blood tank A1.

[0058] The oscillometric electronic sphygmomanometer dynamic traceability device of the present invention has three main innovations:

[0059] First, a relatively complete upper limb arterial vascular system was established, with parameters such as length, diameter, elastic modulus, and thickness close to those of the human body. The system uses bionic muscle tissue and skin, and uses saline and glycerol to mix bionic blood, which is close to physical parameters such as real blood density. The overall device exhibits characteristics close to those of a normal human physiological system, better meeting the working conditions of a sphygmomanometer to detect real human brachial artery blood pressure.

[0060] Secondly, the actual values ​​of brachial artery systolic and diastolic pressure are read by the implanted dynamic pressure sensor. The average value of systolic and diastolic pressure within several cycles after the system stabilizes is used as the standard value, and the error is compared with the average value of several results detected by the sphygmomanometer. This is consistent with the measurement method of the sphygmomanometer detecting the real human body and judging the blood pressure inside the human brachial artery by the blood pressure counting value. It can also directly obtain the actual blood pressure value of the brachial artery at the cuff detection point, realizing direct dynamic traceability of the sphygmomanometer.

[0061] The third is the model of the first and second flow control valves A2 and A13 and the simulated heart A10. By adjusting the valve values, the peripheral resistance of the arterial system can be changed. By adjusting parameters such as blood viscosity, cardiac output, and cardiac frequency, single variables such as hyperlipidemia and heart rate can be controlled and simulated. This solves the experimental research on the influence of single factors that cannot be completed in medical clinical trials. It can conduct single-factor influence on human blood pressure and trend analysis, providing a reliable research foundation for precision medicine and high medical research value. In addition, through the simulation of human blood pressure and the dynamic traceability of electronic blood pressure monitors by this device, rich experimental data can be provided for the further improvement of electronic blood pressure monitors in non-invasive blood pressure measurement in humans, providing strong technical support for the development of new high-precision medical diagnostic equipment.

[0062] The above are preferred embodiments of the present invention. Those skilled in the art may make various changes or improvements based on the above. Without departing from the overall concept of the present invention, these changes or improvements should fall within the scope of protection claimed by the present invention.

Claims

1. A continuously variable diameter flow control valve for simulating vascular peripheral resistance, characterized by: It comprises an upper valve body (2), a blade (3), and a lower base (4); A circle of multiple first-level guide columns (2a) is provided at the lower part of the upper valve body (2); The number of the blades (3) is the same as that of the first-level guide columns (2a); A primary guide groove (3a) adapted to the primary guide column (2a) is provided on the upper portion of each blade (3), so that: the primary guide column (2a) is limited in the primary guide groove (3a) and its relative position in the primary guide groove (3a) can be changed; A secondary guide column (3b) is provided at the lower portion of each blade (3); The upper portion of the lower base (4) is provided with a plurality of secondary guide grooves (4a) the same number as the blades (3), so that: the secondary guide column (3b) is limited in the secondary guide groove (4a) and can change its relative position in the secondary guide groove (4a); The number of the blades (3) is an even number, and they are centrally symmetrical with each other, and there are at least four of them; By rotating the upper valve body (2), a force is applied to the primary guide groove (3a) through the primary guide column (2a), thereby changing the relative position of the primary guide column (2a) in the primary guide groove (3a), and forcing the blade (3) to slide along the secondary guide groove (4a), thereby adjusting the diameter of the central through hole; It also includes two hose quick connectors (1), which are respectively installed at the upper end of the upper valve body (2) and the lower end of the lower base (4); A scale is provided around the upper valve body (2).

2. The continuously variable diameter flow control valve for simulating vascular peripheral resistance according to claim 1, characterized in that: The plurality of secondary guide grooves (4a) are circumscribed in a circle, and adjacent secondary guide grooves (4a) have the same included angle.

3. The continuously variable diameter flow control valve for simulating vascular peripheral resistance according to claim 2, characterized in that: The plurality of primary guide grooves (3a) are arranged radially, or circumscribed to another circle; and adjacent primary guide grooves (3a) have the same included angle.

4. The continuously variable diameter flow control valve for simulating vascular peripheral resistance according to claim 1, characterized in that: The hose quick connector (1) is connected to the upper valve body (2) through standard threads.

5. The continuously variable diameter flow control valve for simulating vascular peripheral resistance according to claim 1, characterized in that: The joints of adjacent blades (3) are provided with a sealing structure.

6. The continuously variable diameter flow regulating valve for simulating vascular peripheral resistance according to claim 1, characterized in that: The slots of the scale (6) are symmetrically distributed on the upper valve body (2).

7. A dynamic tracing device for an oscillometric electronic sphygmomanometer, characterized by: Using the flow control valve according to any one of claims 1 to 6, It also includes a blood-mimicking liquid tank (A1) and a bionic simulation device; The bionic simulation device includes a blood supply pump (A11), a constant temperature simulated blood box (A9), a simulated heart (A10), a stepping motor (A12), a simulated aorta (A8), and a simulated ulnar and radial arteries (A4); The suction end of the blood supply pump (A11) extends into the simulated blood liquid tank (A1), and the output end is connected to the constant temperature simulated blood box (A9); A constant temperature simulated blood box (A9) is connected to a simulated heart (A10); the simulated heart (A10) is a piston cavity, the open end of the piston cavity is connected to the stepper motor (A12), the stepper motor (A12) can step-by-step control the progress of the piston, the closed end of the piston cavity is connected to the simulated aorta (A8), and the simulated aorta (A8) is connected to the simulated ulnar and radial arteries (A4); The front end of the simulated radial and ulnar arteries (A4) is provided with a first flow regulating valve (A2), which extends to the simulated blood liquid tank (A1); The simulated aorta (A8) and the simulated radial and ulnar arteries (A4) are both equipped with a dynamic pressure sensor (A5); The flow regulating valve is installed on at least one of the simulated aorta (A8) and the simulated radial artery (A4).

8. The dynamic tracing device for an oscillometric electronic sphygmomanometer according to claim 7, characterized in that: It also includes a simulated arm skeleton (A3) having a hinge portion, and the connection portion between the simulated aorta (A8) and the simulated radial artery (A4) corresponds to the hinge portion.

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