oxygenator

Abstract

The present invention provides an oxygenator, which relates to the field of medical device technology and includes a shell, a central flow channel, a separation cone, and a core module. The shell is provided with at least a blood inlet and a blood outlet. The central flow channel is provided within the shell. The separation cone is provided within the central flow channel, dividing the central flow channel into multiple sub-flow channels that are not directly connected to each other by fluid, and the sub-flow channel located most upstream is connected to the blood inlet. The core module and the inner wall of the shell form a side wall flow channel. The core module includes multiple working modules arranged at intervals along the axial direction. After blood enters the central flow channel through the blood inlet, it can only diffuse radially through the working modules and flow out from the working modules to the side wall flow channel. Blood entering the side wall flow channel can only flow radially into the downstream working module or flow out through the blood outlet. The oxygenator described in the present invention can improve the uniformity of blood distribution and has better scalability, making it easy to adjust the number of working modules to meet the needs of different people.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an oxygenator. Background Art

[0002] An oxygenator is an artificial device that can perform blood-gas exchange. The oxygenator currently in use has an oxygenation unit installed in the shell, and a side wall flow channel can be formed between the oxygenation unit and the shell, and the oxygenation unit has a cylindrical central flow channel. When blood enters the side wall flow channel from the blood inlet, the blood will be distributed along the side wall flow channel and converge into the central flow channel through the oxygenation unit. Since people of different ages have different requirements for oxygenation, different numbers of oxygenation units need to be installed in the shell. In the prior art, multiple oxygenation units are generally arranged axially in the shell to adjust the oxygenation amount. However, when multiple oxygenators are arranged in series, the blood will gradually distribute along the side wall flow channel, resulting in a low blood distribution amount in the side wall flow channel on the opposite side of the blood inlet, a serious pressure drop, and a dead zone that is prone to thrombosis, thereby increasing the safety risk when using the oxygenator. Summary of the Invention

[0003] In order to overcome the above-mentioned defects of the prior art, the technical problem to be solved by the embodiments of the present invention is to provide an oxygenator for improving the uniformity of blood distribution.

[0004] The above-mentioned object of the present invention can be achieved by adopting the following technical solutions. The present invention provides an oxygenator, comprising:

[0005] The housing is provided with at least a blood inlet, a blood outlet, an oxygenation medium inlet, and an oxygenation medium outlet;

[0006] a central flow channel, disposed in the shell;

[0007] a separation cone, disposed in the central flow channel, dividing the central flow channel into a plurality of relatively independent sub-flow channels that are not directly connected to each other by fluid, wherein the sub-flow channel located most upstream is connected to the blood inlet;

[0008] A core module is disposed in the shell and forms a side wall flow channel with the inner wall of the shell, and includes a plurality of working modules arranged at intervals along the axial direction, each working module being disposed in a one-to-one correspondence with each sub-flow channel;

[0009] The working module includes an oxygenation unit surrounding the corresponding sub-channel and a sealing layer formed at both axial ends of the oxygenation unit; each oxygenation unit is connected to the sidewall channel and the corresponding sub-channel, and the ends of two axially adjacent oxygenation units are connected, so that the oxygenation medium entering from the oxygenation medium inlet flows through all the oxygenation units of the working module and then flows out from the oxygenation medium outlet;

[0010] The sub-flow channel located at the most downstream is connected to the blood outlet, or the side wall flow channel corresponding to the oxygenation unit located at the most downstream is connected to the blood outlet; the sealing layer is used to isolate the blood between the ends of the two axially adjacent working modules, so that after the blood enters the central flow channel through the blood inlet, it can only diffuse radially through the working module and flow out of the working module to the side wall flow channel; the blood entering the side wall flow channel can only flow radially into the downstream working module, or flow out through the blood outlet.

[0011] The technical solution of the present invention has the following significant beneficial effects:

[0012] The central flow channel is divided into multiple relatively independent sub-flow channels that are not directly connected to each other by the separation cone. The blood enters the most upstream sub-flow channel through the blood inlet. The blood flows along the sub-flow channel into the corresponding working module for oxygenation, and then flows into the side wall flow channel. After the side wall flow channel is reversed, it flows into the downstream working module again for oxygenation, and flows back into the downstream sub-flow channel. Finally, the oxygenated blood can be discharged through the blood outlet. The blood can flow in a circuitous manner between the working modules, reducing the height of the side wall flow channel corresponding to each working module, increasing the distribution amount and uniformity of blood in each side wall flow channel, avoiding a large pressure drop of blood in the side wall flow channel, thereby reducing thrombosis and improving safety. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 is a schematic diagram of a three-dimensional structure of the oxygenator of the present invention;

[0014] Figure 2 A cross-sectional view of an installation structure of the separation cone of the oxygenator of the present invention;

[0015] Figure 3 A cross-sectional view of an installation structure of the first, second and third protrusions of the present invention;

[0016] Figure 4 A cross-sectional view of an installation structure of the central flow channel of the oxygenator of the present invention;

[0017] Figure 5 A cross-sectional view of an installation structure of the gas distribution chamber and the exhaust chamber of the oxygenator of the present invention;

[0018] Figure 6 The figure is a schematic diagram of a radial cross-sectional structure of the first end cover of the oxygenator of the present invention.

[0019] Reference numerals in the above drawings:

[0020] 1. Housing; 101. Blood inlet; 102. Blood outlet; 103. Oxygenation medium inlet; 104. Oxygenation medium outlet; 105. Temperature control medium inlet; 106. Temperature control medium outlet; 107. Central flow channel; 108. Sub-flow channel; 109. Sidewall flow channel; 110. Interstitial space; 111. Gas distribution chamber; 112. Exhaust chamber; 113. Liquid distribution chamber; 114. Liquid drainage chamber; 115. First end cap; 116. Second end cap; 117. Exhaust port;

[0021] 2. Separation cone; 21. First protrusion; 22. Upstream portion; 23. Downstream portion; 24. Middle portion;

[0022] 3. Working module; 311. Oxygenation unit; 312. Temperature control unit; 313. Sealing layer;

[0023] 4. Center isolation piece;

[0024] 5. First fixing member; 51. Second protrusion;

[0025] 6. External isolation parts;

[0026] 7. Second fixing member; 71. Third protrusion. DETAILED DESCRIPTION

[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0028] See also Figure 1 and Figure 2 As shown, an embodiment of the present invention provides an oxygenator comprising: a housing 1, a central flow channel 107, a separation cone 2, and a core module. The housing 1 is provided with at least a blood inlet 101, a blood outlet 102, an oxygenation medium inlet 103, and an oxygenation medium outlet 104. The central flow channel 107 is disposed within the housing 1, and the separation cone 2 is disposed within the central flow channel 107. The separation cone 2 divides the central flow channel 107 into a plurality of relatively independent sub-flow channels 108 that are not directly connected to each other by fluid. The sub-flow channel 108 located farthest upstream is connected to the blood inlet 101.

[0029] The core module is housed within the housing 1. The core module and the inner wall of the housing 1 form a sidewall flow channel 109. The core module includes multiple working modules 3 spaced apart along the axial direction, each corresponding to a sub-flow channel 108. The working modules 3 include oxygenation units 311 surrounding the corresponding sub-flow channels 108 and sealing layers 313 formed at both axial ends of the oxygenation units 311.

[0030] Each oxygenation unit 311 is connected to the side wall flow channel 109 and the corresponding sub-flow channel 108 respectively. The ends of two axially adjacent oxygenation units 311 are connected, so that the oxygenation medium entering from the oxygenation medium inlet 103 flows through the oxygenation units 311 of all working modules 3 and then flows out from the oxygenation medium outlet 104.

[0031] The most downstream sub-channel 108 is connected to the blood outlet 102, or the sidewall channel 109 corresponding to the most downstream oxygenation unit 311 is connected to the blood outlet 102. The ends of two axially adjacent working modules 3 are separated by a sealing layer 313 to isolate the blood. After blood enters the central channel 107 through the blood inlet 101, it can only diffuse radially through the working modules 3 and flow out of the working modules 3 into the sidewall channel 109. Blood entering the sidewall channel 109 can only flow radially into the downstream working module 3 or out through the blood outlet 102.

[0032] The separation cone 2 divides the central flow channel 107 into multiple relatively independent sub-flow channels 108, each of which is not directly connected to the other. Blood enters the upstream sub-flow channel 108 through the blood inlet 101. The blood flows along the sub-flow channel 108 into the corresponding working module 3 for oxygenation, then flows into the side wall flow channel 109. After reversing through the side wall flow channel 109, the blood flows again into the downstream working module 3 for oxygenation, and then flows back into the downstream sub-flow channel 108. Finally, the oxygenated blood can be discharged through the blood outlet 102.

[0033] Blood can flow in a circuitous manner between the working modules 3, reducing the height of the side wall flow channels 109 corresponding to each working module 3, increasing the distribution amount and uniformity of blood in each side wall flow channel 109, avoiding a large pressure drop of blood in the side wall flow channel 109, thereby reducing blood clots and improving safety.

[0034] like Figure 2 As shown, a central isolator 4 is provided in the housing 1, the central isolator 4 forming a central flow channel 107, and the oxygenation membrane filaments of the oxygenation unit 311 are wound around the central isolator 4. The central isolator 4 is generally cylindrical, and the inner cavity forms the central flow channel 107.

[0035] like Figure 2 、 Figure 4 and Figure 5As shown, by placing the separation cone 2 within the central partition 4, the separation cone 2 can divide the central flow channel 107 into multiple relatively independent sub-flow channels 108 that are not directly connected to each other. In addition, the oxygenation membrane filaments of the oxygenation unit 311 are wound outside the central partition 4, so that blood can flow through the oxygenation membrane filaments of the oxygenation unit 311 through the sub-flow channels 108 for oxygenation, or blood can flow back into the sub-flow channels 108 through the oxygenation membrane filaments of the oxygenation unit 311.

[0036] like Figure 2 As shown, two axially adjacent sealing layers 313 are spaced apart to form a gap space 110, and two axially adjacent oxygenation units 311 are connected through the gap space 110. In one embodiment, the two axially adjacent sealing layers 313 are the same sealing layer 313, and the two axially adjacent oxygenation units 311 share a common oxygenation membrane filament, which passes through the sealing layer 313. By integrating the two axially adjacent sealing layers 313 of each oxygenation unit 311, the integration between the working modules 3 is improved, and the volume of the oxygenator is reduced.

[0037] In other feasible implementations, several working modules 3 may be set as a group, and the axially adjacent sealing layers 313 in the same group may be set as the same sealing layer 313, while the sealing layers 313 in different groups may be set at intervals.

[0038] like Figure 3 As shown, the outer wall of the separation cone 2 is formed with a radially outwardly projecting first protrusion 21, which is inserted into the gap space 110. By providing the outwardly projecting first protrusion 21, at least a portion of the first protrusion 21 can pass through the central spacer 4 and be disposed in the gap space 110 between the two sealing layers 313. The first protrusion 21 positions and supports the two sealing layers 313, thereby ensuring that axially adjacent working modules 3 are spaced apart and that the axial spacing between adjacent working modules 3 is stably maintained.

[0039] like Figure 3As shown, the outer walls of two axially adjacent sealing layers 313 are provided with a generally cylindrical first fixing member 5. The axial ends of the first fixing member 5 are fixedly connected to the two axially adjacent sealing layers 313. The inner wall of the first fixing member 5 is provided with a radially inwardly projecting second protrusion 51, which is inserted into the gap space 110. The first fixing member 5 cooperates with the first protrusion 21 to radially seal both ends of the gap space 110, preventing undesirable axial flow of the oxygenation medium into the adjacent downstream oxygenation unit 311. Furthermore, the first fixing member 5 also positions and supports the two sealing layers 313, improving the positioning accuracy between adjacent working modules 3. When multiple working modules 3 are provided, the first protrusion 21 and the second protrusion 51 enable expansion and installation between the multiple working modules 3, significantly improving the scalability of the oxygenator.

[0040] like Figure 2 In this embodiment, the working module 3 further includes a temperature control unit 312. The temperature control unit 312 is cylindrical and disposed outside the oxygenation unit 311. The temperature control unit 312 forms a sidewall flow channel 109 with the inner wall of the housing 1. The temperature control unit 312 can adjust the temperature of the blood before it enters the oxygenation unit 311, for example by increasing or maintaining the temperature, to maintain the blood within an optimal oxygenation temperature range and improve oxygenation efficiency.

[0041] Likewise, two axially adjacent temperature control units 312 are connected via the gap space 110 , so that the temperature control medium can flow through all the temperature control units 312 without having to control each temperature control unit 312 separately.

[0042] Similarly, in one embodiment, two axially adjacent sealing layers 313 are the same sealing layer 313, and two axially adjacent temperature control units 312 share a common temperature control membrane filament, which passes through the sealing layer 313. This improves the integration of the temperature control unit 312 and reduces the volume of the oxygenator. The sealing layer 313 on the temperature control unit 312 is integrated with the sealing layer 313 on the oxygenation unit 311, thereby improving the integration between the temperature control unit 312 and the oxygenation unit 311.

[0043] The housing 1 is provided with an outer isolator 6 located outside the central isolator 4. The temperature control membrane of the temperature control unit 312 is wound outside the outer isolator 6. The two ends of the outer isolator 6 are respectively inserted into the sealing layer 313 at both ends. Figure 2 and Figure 3 As shown, the outer isolator 6 is generally cylindrical and is positioned around the periphery of the oxygenation unit 311. The temperature control membrane filaments of the temperature control unit 312 are wound around the outer isolator 6. Furthermore, the outer isolator 6 is inserted between axially adjacent sealing layers 313. By utilizing the sealing layers 313, the outer isolator 6 can be quickly positioned and installed, improving the installation efficiency of the outer isolator 6.

[0044] The temperature control membrane wire is wound around the outer isolator 6, thereby simultaneously improving the installation efficiency of the temperature control unit 312 through the outer isolator 6, so that the temperature control unit 312 can form a more controllable positional relationship with the radially opposite oxygenation unit 311, thereby improving the uniformity of blood flow between the temperature control unit 312 and the oxygenation unit 311.

[0045] The outer partition 6 has a flow-through structure, and blood passing through the oxygenation unit 311 can flow through the outer partition 6 into the temperature control unit 312, and then flow into the side wall flow channel 109. Alternatively, the blood in the side wall flow channel 109 can pass through the temperature control unit 312 and the outer partition 6, and then flow into the oxygenation unit 311.

[0046] like Figure 3 In this embodiment, a generally cylindrical second fixing member 7 is provided between two axially adjacent sealing layers 313. The axial ends of the second fixing member 7 are inserted into the two axially adjacent sealing layers 313 and face the ends of the two axially adjacent outer spacers 6. The second fixing member 7 divides the interstitial space 110 into two fluid-isolated sections: an inner oxygenation medium flow space and an outer temperature control medium flow space. The two axially adjacent oxygenation units 311 are connected via the oxygenation medium flow space, and the two axially adjacent temperature control units 312 are connected via the temperature control medium flow space.

[0047] The first fixing member 5 is disposed between two axially adjacent sealing layers 313 at the outermost edges. Specifically, the first fixing member 5 is disposed around the second fixing member 7. In one embodiment, the second fixing member 7 has a single-sided cross-section that is tapered at both ends and thickened in the middle. A generally annular third protrusion 71 is formed in the center and inserted into the gap 110.

[0048] The third protrusion 71 cooperates with the first protrusion 21 to radially seal the gap 110 between adjacent oxygenation units 311, preventing leakage of the oxygenation medium during flow. The third protrusion 71 cooperates with the second protrusion 51 to radially seal the gap 110 between adjacent temperature control units 312, preventing leakage of the temperature control medium during flow.

[0049] Furthermore, the third protrusion 71 can also position and support the adjacent temperature control unit 312 and oxygenation unit 311 , thereby improving the positioning accuracy between the adjacent temperature control unit 312 and oxygenation unit 311 .

[0050] The first protrusion 21, the second protrusion 51, and the third protrusion 71 cooperate to improve the scalability and installation efficiency between adjacent oxygenation units 311 and temperature control units 312. In addition, the first protrusion 21, the second protrusion 51, and the third protrusion 71 can also control the size of the gap space 110 between adjacent oxygenation units 311 and the size of the gap space 110 between adjacent temperature control units 312, so that the oxygenation medium and the temperature control medium can pass through the gap space 110 more evenly.

[0051] like Figure 2 、 Figure 4 and Figure 5 As shown, the separation cone 2 includes an upstream portion 22 located in the most upstream sub-channel 108 and a downstream portion 23 located in the most downstream sub-channel 108. As blood flows from the blood inlet 101 to the downstream, the outer diameter of the upstream portion 22 gradually increases. As blood flows from the blood outlet 102 to the upstream, the outer diameter of the downstream portion 23 gradually increases.

[0052] By adjusting the outer diameter of the separation cone 2 along the axial direction, the separation cone 2 can better divert blood in the central flow channel 107, so that the blood can evenly enter the oxygenation unit 311 along the sub-flow channel 108, or the blood can evenly flow from the oxygenation unit 311 into the sub-flow channel 108, thereby avoiding the problem of uneven distribution of blood due to pressure drop.

[0053] When there are two working modules 3, the separation cone 2 only includes an upstream portion 22 and a downstream portion 23. The upstream portion 22 can evenly distribute the blood, and the downstream portion 23 can evenly collect the blood.

[0054] When the number of the working modules 3 is greater than 2, the separation cone 2 further includes a middle portion 24 located between the upstream portion 22 and the downstream portion 23 , and the outer diameter of the middle portion 24 remains unchanged.

[0055] The oxygenation membrane filament has a gas phase inlet and a gas phase outlet. The sealing layer 313 at one end of the oxygenation unit 311 located most upstream forms a gas distribution chamber 111 with the housing 1. The oxygenation medium inlet 103 communicates with the gas distribution chamber 111. The sealing layer 313 at one end of the oxygenation unit 311 located most downstream forms an exhaust chamber 112 with the housing 1. The oxygenation medium outlet 104 communicates with the exhaust chamber 112.

[0056] An annular gas distribution chamber 111 is formed between the sealing layer 313 at one end of the upstream-most oxygenation unit 311 and the housing 1. The oxygenation medium inlet 103 can input oxygenation medium into the gas distribution chamber 111. The oxygenation medium can evenly enter the gas phase inlet of the oxygenation membrane through the annular gas distribution chamber 111, thereby improving the uniformity of the oxygenation medium distribution. An annular exhaust chamber 112 is formed between the sealing layer 313 at one end of the downstream-most oxygenation unit 311 and the housing 1. The oxygenation medium passing through each oxygenation unit 311 ultimately flows into the exhaust chamber 112 and is discharged through the oxygenation medium outlet 104.

[0057] like Figure 1 and Figure 6 As shown, the housing 1 is further provided with a temperature control medium inlet 105 and a temperature control medium outlet 106. The temperature control medium inlet 105 is connected to the liquid phase inlet of the temperature control unit 312 located at the farthest upstream, while the temperature control medium outlet 106 is connected to the liquid phase outlet of the temperature control unit 312 located at the farthest downstream. The temperature control medium inlet 105 can input the temperature control medium into the temperature control unit 312, while the temperature control medium outlet 106 can discharge the temperature control medium. The temperature control medium can be used to regulate the temperature of the blood passing through the temperature control unit 312, thereby achieving a better oxygenation effect.

[0058] The sealing layer 313 at one end of the temperature control unit 312 located most upstream forms a liquid distribution chamber 113 with the housing 1, and the temperature control medium inlet 105 communicates with the liquid distribution chamber 113. The sealing layer 313 at one end of the temperature control unit 312 located most downstream forms a liquid drainage chamber 114 with the housing 1, and the temperature control medium outlet 106 communicates with the liquid drainage chamber 114.

[0059] An annular liquid distribution chamber 113 is formed between the sealing layer 313 at one end of the upstreammost temperature control unit 312 and the housing 1. This liquid distribution chamber 113 can be positioned outside the gas distribution chamber 111. A temperature control medium inlet 105 can be fed into the liquid distribution chamber 113. This medium, passing through the annular liquid distribution chamber 113, evenly enters the liquid phase inlet of the temperature control membrane of the temperature control unit 312, improving the uniformity of the temperature control medium distribution.

[0060] An annular drainage chamber 114 is formed between the sealing layer 313 at one end of the temperature control unit 312 located at the most downstream end and the shell 1. The temperature control medium passing through each temperature control unit 312 can eventually flow into the drainage chamber 114 and be discharged through the temperature control medium outlet 106.

[0061] The housing 1 is detachably provided with a first end cap 115 and a second end cap 116 at both ends. The first end cap 115 is provided with at least a blood inlet 101 and an oxygenation medium inlet 103, while the second end cap 116 is provided with at least a blood outlet 102 and an oxygenation medium outlet 104. The first end cap 115 and the sealing layer 313 at one end of the oxygenation unit 311 located most upstream form an air distribution chamber 111, and the second end cap 116 and the sealing layer 313 at one end of the temperature control unit 312 located most upstream form a liquid distribution chamber 113. The second end cap 116 and the sealing layer 313 at one end of the oxygenation unit 311 located most downstream form an exhaust chamber 112, and the second end cap 116 and the sealing layer 313 at one end of the temperature control unit 312 located most downstream form a liquid drainage chamber 114.

[0062] In other embodiments, the liquid distribution chamber 113 may be provided on the second end cap 116, and the liquid drainage chamber 114 may be provided on the first end cap 115. The temperature control medium outlet 106 is correspondingly provided on the first end cap 115, and the temperature control medium inlet 105 is correspondingly provided on the second end cap 116. By making the flow direction of the temperature control medium opposite to that of the blood, the output blood temperature can be better controlled.

[0063] By providing a first end cap 115 and a second end cap 116 at both ends of the housing 1, the oxygenation unit 311 and the temperature control unit 312 can be quickly installed and secured within the housing 1 by removing the first end cap 115 and / or the second end cap 116. This reduces the difficulty of assembling the oxygenation unit 311 and the temperature control unit 312 and facilitates maintenance and replacement of the oxygenation unit 311 and the temperature control unit 312. An exhaust port 117 can be provided on the first end cap 115. The exhaust port 117 communicates with the upstreammost sub-channel 108, allowing air in the central channel 107 to be exhausted through the exhaust port 117.

[0064] Each embodiment in this specification is described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the embodiments can be referred to each other. The above embodiments are only for illustrating the technical concept and features of the present invention. Their purpose is to enable people familiar with this technology to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the scope of protection of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the scope of protection of the present invention.

Claims

1. An oxygenator, characterized in that include: The housing is provided with at least a blood inlet, a blood outlet, an oxygenation medium inlet, and an oxygenation medium outlet; a central flow channel, disposed in the shell; a separation cone, disposed in the central flow channel, dividing the central flow channel into a plurality of relatively independent sub-flow channels that are not directly connected to each other by fluid, wherein the sub-flow channel located most upstream is connected to the blood inlet; A core module is disposed in the shell and forms a side wall flow channel with the inner wall of the shell, and includes a plurality of working modules arranged at intervals along the axial direction, each working module being disposed in a one-to-one correspondence with each sub-flow channel; The working module includes an oxygenation unit surrounding the corresponding sub-channel and a sealing layer formed at both axial ends of the oxygenation unit; each oxygenation unit is connected to the sidewall channel and the corresponding sub-channel, and the ends of two axially adjacent oxygenation units are connected, so that the oxygenation medium entering from the oxygenation medium inlet flows through all the oxygenation units of the working module and then flows out from the oxygenation medium outlet; The sub-flow channel located at the most downstream is connected to the blood outlet, or the side wall flow channel corresponding to the oxygenation unit located at the most downstream is connected to the blood outlet; the sealing layer is used to isolate the blood between the ends of the two axially adjacent working modules, so that after the blood enters the central flow channel through the blood inlet, it can only diffuse radially through the working module and flow out of the working module to the side wall flow channel; the blood entering the side wall flow channel can only flow radially into the downstream working module, or flow out through the blood outlet.

2. The oxygenator according to claim 1, wherein The two axially adjacent sealing layers and the separation cone are sealed at the connection; A central isolator is provided in the shell, the central isolator forms the central flow channel, and the oxygenation membrane filaments of the oxygenation unit are wound outside the central isolator; A gap space is formed between the two axially adjacent sealing layers, and the two axially adjacent oxygenation units are connected through the gap space; or, the two axially adjacent sealing layers are the same sealing layer, and the two axially adjacent oxygenation units share the oxygenation membrane filament, and the oxygenation membrane filament passes through the sealing layer.

3. The oxygenator according to claim 2, wherein: The outer wall of the separation cone is formed with a first protrusion protruding radially outward, and the first protrusion is inserted into the gap space; The outer walls of the two axially adjacent sealing layers are provided with a first fixing member that is roughly cylindrical, and the axial ends of the first fixing member are fixedly connected to the two axially adjacent sealing layers. The inner wall of the first fixing member is provided with a second radially inward protrusion, and the second protrusion is inserted into the gap space.

4. The oxygenator according to claim 3, wherein The working module further includes a temperature control unit, which has a cylindrical structure and is arranged on the periphery of the oxygenation unit. The temperature control unit and the inner wall of the shell form the side wall flow channel; The two axially adjacent temperature control units are connected through the gap space; or, the two axially adjacent sealing layers are the same sealing layer, and the two axially adjacent temperature control units share a temperature control membrane wire, and the temperature control membrane wire passes through the sealing layer.

5. The oxygenator according to claim 4, wherein An outer isolating member located outside the central isolating member is provided in the shell, and the temperature control membrane wire of the temperature control unit is wound outside the outer isolating member. The two ends of the outer isolating member are respectively inserted into the sealing layers at both ends. A second fixing member that is roughly cylindrical is provided in the two axially adjacent sealing layers. The axial ends of the second fixing member are inserted into the two axially adjacent sealing layers and are opposite to the ends of the two axially adjacent outer isolating members.

6. The oxygenator according to claim 5, wherein The second fixing member has a shape of thin ends and thick middle in a single-side cross section, and a third protrusion of substantially annular shape is formed in the middle of the second fixing member, and the third protrusion is inserted into the gap space; The second fixing member divides the gap space into two fluid-independent parts: an oxygenation medium flow space located on the inner side and a temperature control medium flow space located on the outer side; two axially adjacent oxygenation units are connected through the oxygenation medium flow space, and two axially adjacent temperature control units are connected through the temperature control medium flow space.

7. The oxygenator according to claim 1, wherein The separation cone includes an upstream portion of the sub-channel located most upstream and a downstream portion of the sub-channel located most downstream; wherein, in a direction from the blood inlet to the downstream, the outer diameter of the upstream portion gradually increases; and in a direction from the blood outlet to the upstream, the outer diameter of the downstream portion gradually increases; When the number of the working modules is 2, the separation cone only includes the upstream part and the downstream part; when the number of the working modules is greater than 2, the separation cone also includes a middle part located between the upstream part and the downstream part, and the outer diameter of the middle part remains unchanged.

8. The oxygenator according to claim 4, wherein The oxygenation membrane filament has a gas phase inlet and a gas phase outlet. The sealing layer at one end of the oxygenation unit located most upstream forms a gas distribution chamber with the shell, and the oxygenation medium inlet is connected to the gas distribution chamber; the sealing layer at one end of the oxygenation unit located most downstream forms an exhaust chamber with the shell, and the oxygenation medium outlet is connected to the exhaust chamber.

9. The oxygenator according to claim 8, wherein The shell is also provided with a temperature control medium inlet and a temperature control medium outlet. The temperature control medium inlet is connected to the liquid phase inlet of the temperature control unit located at the most upstream, and the temperature control medium outlet is connected to the liquid phase outlet of the temperature control unit located at the most downstream.

10. The oxygenator according to claim 9, wherein The sealing layer at one end of the temperature control unit located most upstream and the shell form a liquid distribution chamber, and the temperature control medium inlet is connected to the liquid distribution chamber; the sealing layer at one end of the temperature control unit located most downstream and the shell form a liquid drainage chamber, and the temperature control medium outlet is connected to the liquid drainage chamber.

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