Temperature control device and method for microfluidic chip

By setting an equivalent temperature sensing chip on the temperature control board and using a temperature sensor to monitor and regulate the output temperature of the temperature control board, the problems of inaccurate temperature control and high cost of microfluidic chips are solved, achieving precise temperature control and cost reduction.

CN116880599BActive Publication Date: 2026-06-19BEIJING MECHANICAL EQUIP INST
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Patent Information

Application Number
CN202310789602.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-06-29
Publication Date
2026-06-19
Estimated Expiration
2043-06-29

AI Technical Summary

Technical Problem

Existing microfluidic chip temperature control methods suffer from inaccurate temperature measurement and high cost. In particular, unstable internal temperature control and sensor implantation increase chip cost while compressing flow channel space.

Method used

By setting an equivalent temperature sensing chip on the temperature control board, using a temperature sensor to monitor the temperature of the equivalent temperature sensing chip, and adjusting the output temperature of the temperature control board according to the estimated temperature, precise temperature control of the microfluidic chip to be controlled can be achieved, avoiding the cost and space compression caused by sensor implantation.

Benefits of technology

This technology enables precise temperature control of microfluidic chips, reduces application costs, improves the accuracy and stability of temperature measurement, and avoids the complexity and space occupation of sensor implantation.

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Abstract

This invention discloses a temperature control device and method for microfluidic chips, comprising: arranging a microfluidic chip to be temperature-controlled at a first position on a temperature control plate; arranging an equivalent temperature sensing chip at a second position adjacent to the first position on the temperature control plate; embedding a temperature sensor in the equivalent temperature sensing chip and monitoring the temperature of the equivalent temperature sensing chip through the temperature sensor; estimating the temperature of the microfluidic chip to be temperature-controlled based on the monitored temperature of the equivalent temperature sensing chip; and adjusting the output temperature of the temperature control plate according to the estimated temperature of the microfluidic chip to be temperature-controlled and a target temperature. This invention indirectly monitors the temperature of the chip to be temperature-controlled by configuring an equivalent temperature sensing chip, and adjusts the output temperature of the temperature control plate according to the monitored temperature of the equivalent temperature sensing chip and the target temperature. This allows for accurate monitoring of the temperature of the chip to be temperature-controlled without embedding a sensor in the chip, thereby enabling precise temperature control of the chip through the temperature control plate.
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