Poultry additive and method for raising poultry using the same

Abstract

The invention discloses a poultry additive and a method for raising poultry, comprising preparing a clear paste from 35-50 parts of dry raw materials, including pine needles, 30-35 parts of honeysuckle, 30-35 parts of forsythia, 25-30 parts of dandelion, 25-30 parts of houttuynia cordata, 15-25 parts of beam dryness, 15-20 parts of patrinia herba, 7-15 parts of indigo naturalis and 5-15 parts of oldenlandia diffusa, adding silicon dioxide powder to the clear paste, mixing the mixture evenly and drying the mixture to obtain a powdered additive A, or adding aged vinegar to the clear paste, mixing the mixture evenly to obtain a liquid additive B, wherein the weight ratio of the clear paste to the silicon dioxide powder is 1:5-6, and the weight ratio of the clear paste to the aged vinegar is 1:10-12. The additive obtained by the exquisite compatibility of traditional Chinese medicine is used for a poultry breeding method, and can prevent and treat diseases that are easily transmitted by poultry, thereby improving the immune function of poultry.

Description

Technical Field

[0001] The present invention relates to the technical field of poultry breeding, and more particularly to a poultry additive and a method for raising poultry using the additive. Background Art

[0002] All domesticated poultry today belongs to the class Aves, a vertebrate group. To enable flight, birds have evolved a dual breathing system. In addition to lungs, birds also have thin membrane-like air sacs protruding from the lung walls. There are nine main air sacs, extending into the cavities between internal organs, muscles, and bones. When resting, birds breathe primarily through the lungs, relying on the movement of their intercostal and abdominal muscles. When flying, they breathe primarily through the movement of their pectoral muscles. Gas enters the air sacs through the lungs and is then expelled from them. Due to the expansion and contraction of the air sacs, gas exchange occurs twice in the lungs. This breathing method, which allows for gas exchange in the lungs during both inhalation and exhalation, is called dual breathing, a specialized adaptation for birds to fly. Poultry, as birds themselves, also possess organs for this dual breathing system.

[0003] In recent years, with the booming poultry farming industry, poultry farming has developed towards large-scale and intensive production. This highly intensive farming model has made poultry susceptible to a variety of diseases. In particular, the "double breathing" system, which evolved for flight, makes poultry more susceptible to various respiratory diseases than livestock and more difficult to treat. Avian respiratory diseases can be caused by a variety of factors, including viral respiratory diseases such as Newcastle disease and avian influenza; bacterial respiratory diseases such as Escherichia coli; mycoplasma respiratory diseases such as respiratory mycoplasma; and other diseases such as coccidiosis.

[0004] Therefore, it is of great significance to develop an additive for poultry breeding that is green, environmentally friendly, effective, stable, and can ensure meat quality. Summary of the Invention

[0005] An object of the present invention is to solve at least the above problems and to provide at least the advantages which will be described hereinafter.

[0006] The invention aims at the fact that poultry are prone to various respiratory diseases and other easily transmitted diseases during breeding. The additive obtained by the exquisite combination of traditional Chinese medicines is used in the poultry breeding method, which can prevent and treat the easily transmitted diseases of poultry and improve the immune function of poultry.

[0007] To achieve these objectives and other advantages according to the present invention, the present invention provides a poultry additive, which comprises preparing a paste by weight of dry raw materials including 35-50 parts of pine needles, 30-35 parts of honeysuckle, 30-35 parts of forsythia, 25-30 parts of dandelion, 25-30 parts of houttuynia cordata, 15-25 parts of belamcanda chinensis, 15-20 parts of patrinia herb, 7-15 parts of indigo naturalis, and 5-15 parts of oldenlandia diffusa; adding silicon dioxide powder to the paste, mixing uniformly, and drying to obtain a powdered additive A; or adding aged vinegar to the paste, mixing uniformly, to obtain a liquid additive B; wherein the weight ratio of the paste to the silicon dioxide powder is 1:5-6, and the weight ratio of the paste to the aged vinegar is 1:10-12.

[0008] Preferably, the clear paste is prepared by the following method:

[0009] 1) grinding the dry raw materials by weight into 50-60 mesh powder;

[0010] 2) Add boiling water to the powder and stir to form a paste, then freeze at -25°C for 24-25 hours. Then take out the frozen paste and thaw it at room temperature;

[0011] 3) The thawed mixture is mixed with 95% ethanol solution in a weight ratio of 1:1-2, extracted at room temperature for 3-4 hours, and filtered three times. The filtrates are combined and distilled under reduced pressure to remove the ethanol, and concentrated on a vacuum rotary apparatus to prepare a clear paste with a relative density of 1.18-1.25.

[0012] Preferably, the step 2) further comprises crushing the frozen paste into 50-60 mesh pieces and then thawing at room temperature.

[0013] Preferably, the powdered additive A is uniformly mixed and dried according to a weight ratio of silicon dioxide powder: clear paste: cyclodextrin: brown sugar of 500:100:0.1-0.5:3-10; and the liquid additive B is uniformly mixed according to a weight ratio of aged vinegar: clear paste: cyclodextrin: brown sugar of 1000:100:0.1-0.5:3-10.

[0014] The present invention also provides a method for raising poultry, which uses the above additives.

[0015] When the poultry is 1-2 weeks old, the powdered additive A is added to the poultry feed at an addition amount of 500 ppm;

[0016] When the poultry is 3-4 weeks old, the powdered additive A is added to the poultry feed at an addition amount of 200 ppm;

[0017] After the poultry is 5 weeks old, the powdered additive A is added to the poultry feed at an addition amount of 100 ppm.

[0018] The present invention also provides another method for raising poultry, wherein the above-mentioned additive is used in treating respiratory diseases of poultry during the raising process, specifically comprising: uniformly mixing the liquid additive B and water in a volume ratio of 1:5-10 to obtain a mixed liquid; atomizing and spraying the poultry at a dosage of 0.1 ml of the mixed liquid per poultry according to a single lesion site in the upper respiratory tract, lower respiratory tract, or air sac; and if multiple respiratory system lesions occur, the dosage of the mixed liquid is increased by 0.1 ml per poultry for each additional lesion site, and the spraying is performed once a day for 3-5 consecutive days.

[0019] Preferably, during the atomization spraying process for poultry, the doors and windows of the poultry house and the exhaust system need to be closed before spraying. After spraying, the doors and windows and the exhaust system continue to be closed for 30-60 minutes to allow the droplets to be suspended in the air of the poultry house. After 30-60 minutes, the poultry house is ventilated.

[0020] Preferably, when poultry show upper respiratory tract infection, an atomizing nozzle with a droplet diameter of 5-10 μm is selected for spraying; when poultry show lower respiratory tract infection, an atomizing nozzle with a droplet diameter of 1-4 μm is selected for spraying; when poultry show air sac infection, an atomizing nozzle with a droplet diameter of 0.1-2 μm is selected for spraying; when multiple parts of the respiratory system of poultry are infected with different pathogens, atomizing nozzles with multiple droplet diameters are selected for spraying according to the autopsy symptoms of dead birds.

[0021] The present invention has at least the following beneficial effects:

[0022] First, the present invention uses a sophisticated combination of Chinese medicines, with pine needles as the main drug, honeysuckle, indigo naturalis and oldenlandia diffusa as the ministerial drugs, and the others as adjuvants and guiding drugs. Pine needles have antiviral, antibacterial and immune-enhancing effects, but their medicinal properties are warm and hot, and long-term feeding can easily cause febrile diseases in poultry, which is detrimental to poultry growth. Now, by adding honeysuckle, indigo naturalis and oldenlandia diffusa, the drug has the effects of detoxifying the lungs, clearing the liver and purging heart fire, and the medicinal properties are harmonious, which has a preventive and therapeutic effect on poultry susceptible diseases and improves immune function, making it suitable for feeding and treating poultry at all growth stages.

[0023] Second, the present invention facilitates the dissolution of active ingredients and improves drug efficacy by crushing the frozen paste again.

[0024] Third, the present invention increases poultry feed intake and absorption by blending cyclodextrin, brown sugar and extract, which is further beneficial to improving poultry immune function and poultry meat quality.

[0025] The properties and flavors of the used Chinese medicine of the present invention are as follows:

[0026] Pine needles: Bitter in taste, warm in nature; enter the Heart and Spleen meridians. They dispel wind and dampness, kill insects and relieve itching, promote blood circulation and calm the mind. They treat rheumatic pain, athlete's foot, eczema, ringworm, urticaria, traumatic injuries, neurasthenia, chronic nephritis, hypertension, and prevent Japanese encephalitis and influenza.

[0027] Honeysuckle: Sweet and cold in nature. It enters the lung, stomach, and large intestine meridians. It clears heat, detoxifies, and dispels wind-heat. It is used to treat carbuncles, sores, sore throat, erysipelas, dysentery caused by heat toxins, wind-heat colds, and fever caused by febrile diseases.

[0028] Forsythia: Bitter and cooling in nature, it enters the Heart, Liver, and Gallbladder meridians. It clears heat, detoxifies, disperses stagnation, and reduces swelling. It is used to treat febrile illnesses, erysipelas, rashes, carbuncles, ulcers, scrofula, and stranguria.

[0029] Dandelion: Bitter and sweet, cold, enters the liver and stomach meridians. Clears heat and detoxifies, acts as a diuretic and resolves stagnation. Treats acute mastitis, lymphadenitis, scrofula, carbuncle, acute conjunctivitis, colds and fevers, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, and urinary tract infections.

[0030] Houttuynia cordata: Pungent, slightly warm. Clears away heat and detoxifies, acts as a diuretic and reduces swelling. Treats pneumonia, lung abscesses, febrile dysentery, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoids, rectal prolapse, eczema, baldness, and scabies.

[0031] Belamcanda: Bitter, cold. Clears heat and detoxifies, eliminates phlegm, and relieves sore throat. Treats heat, phlegm, fire stagnation, sore throat, excessive phlegm, cough and asthma.

[0032] Patrinia scabra: It has pungent, bitter, and slightly cold properties and enters the stomach, large intestine, and liver meridians. It has the effects of clearing away heat and detoxifying, dispelling pus from carbuncles, and removing blood stasis and relieving pain.

[0033] Indigo: salty, cold, Clears heat and detoxifies , cools blood and eliminates spots, purges fire and calms the nerves. Warm toxicity causing rash , blood heat vomiting and epistaxis, Chest pain and coughing up blood , mouth sore , mumps , Throat paralysis , epilepsy in children.

[0034] Hedyotis diffusa: bitter, light, and cold in nature. Its main functions are clearing away heat and detoxifying, relieving pain and dispersing stagnation, and promoting diuresis and removing dampness.

[0035] Other advantages, objectives and features of the present invention will be reflected in part through the following description, and in part will be understood by those skilled in the art through study and practice of the present invention. DETAILED DESCRIPTION

[0036] The present invention is further described in detail below with reference to the embodiments so that those skilled in the art can implement the invention with reference to the description.

[0037] It should be understood that terms such as “having,” “including,” and “comprising” used herein do not prescribe the existence or addition of one or more other elements or combinations thereof.

[0038] It should be noted that the experimental methods described in the following embodiments are conventional methods unless otherwise specified, and the reagents and materials can be obtained from commercial channels unless otherwise specified; the moisture content of dry medicinal materials is usually 8-12%, that is, the moisture content of the dry weight parts of raw materials used in this application is 8-12%.

[0039] Example 1

[0040] A poultry additive comprising 35 parts of dry raw materials by weight: pine needles 35 parts, honeysuckle 30 parts, forsythia suspensa 30 parts, dandelion 25 parts, houttuynia cordata 25 parts, belamcanda 15 parts, patrinia scabra 15 parts, indigo naturalis 7 parts and oldenlandia diffusa 5 parts;

[0041] Prepared by the following preparation method:

[0042] 1) Grind the above dry raw materials by weight into 50 mesh powder;

[0043] 2) Add boiling water to the powder and stir to form a paste, then freeze at -25°C for 24 hours. Then, crush the frozen paste into 50-mesh pieces again and thaw at room temperature.

[0044] 3) The thawed mixture was mixed with 95% ethanol solution in a weight ratio of 1:1, and the mixture was extracted at room temperature for 3 hours. The extraction was repeated three times, and the filtrates were combined and distilled under reduced pressure to remove the ethanol. The mixture was concentrated on a vacuum rotary apparatus to obtain a clear paste with a relative density of 1.18-1.25.

[0045] 4) Silicon dioxide powder: clear paste: cyclodextrin: brown sugar in a weight ratio of 500:100:0.1:3 are mixed evenly and dried to obtain powdered additive A; aged vinegar: clear paste: cyclodextrin: brown sugar in a weight ratio of 1000:100:0.1:3 are mixed evenly to obtain liquid additive B.

[0046] Example 2

[0047] A poultry additive, comprising 50 parts by weight of dry raw materials: pine needles, 35 parts of honeysuckle, 35 parts of forsythia, 30 parts of dandelion, 30 parts of houttuynia, 25 parts of belamcanda chinensis, 20 parts of patrinia herba, 15 parts of indigo naturalis and 15 parts of oldenlandia diffusa;

[0048] Prepared by the following preparation method:

[0049] 1) Grinding the above dry raw materials into 60 mesh powder;

[0050] 2) Add boiling water to the powder and stir to form a paste, then freeze at -25°C for 25 hours. Then, crush the frozen paste into 60-mesh pieces and thaw at room temperature.

[0051] 3) The thawed mixture was mixed with 95% ethanol solution in a weight ratio of 1:2, and the mixture was extracted at room temperature for 4 hours. The extraction was repeated three times, and the filtrates were combined and distilled under reduced pressure to remove the ethanol. The mixture was concentrated on a vacuum rotary apparatus to obtain a clear paste with a relative density of 1.18-1.25.

[0052] 4) Silicon dioxide powder: clear paste: cyclodextrin: brown sugar in a weight ratio of 500:100:0.1-0.5:3-10 are mixed evenly and dried to obtain powdered additive A; aged vinegar: clear paste: cyclodextrin: brown sugar in a weight ratio of 1000:100:0.1-0.5:3-10 are mixed evenly to obtain liquid additive B.

[0053] Example 3

[0054] A poultry additive. The raw materials used in Example 3 are the same as those in Example 1. The only difference in the preparation method is that the frozen paste is not re-ground into a 50-mesh size in step 2). Specifically, step 2) of Example 3 is as follows: boiling water is added to the powder, stirred to form a paste, and then frozen at -25°C for 24 hours. The frozen paste is then removed and thawed at room temperature.

[0055] Example 4

[0056] A poultry additive. The raw materials of Example 4 are the same as those of Example 1. The only difference in the preparation method is that cyclodextrin and brown sugar are not included in step 4). Specifically, step 4) of Example 4 comprises: uniformly mixing silicon dioxide powder and clear paste in a weight ratio of 5:1 and drying to obtain powdered additive A; and uniformly mixing aged vinegar and clear paste sugar in a weight ratio of 10:1 to obtain liquid additive B.

[0057] Comparative Example 1

[0058] An additive, the preparation method of this comparative example 1 is the same as the preparation method of Example 1, the only difference in the raw materials is that Patrinia scabra, Indigo Naturalis and Hedyotis diffusa are not included. Specifically, the raw materials include 35 parts of dry weight parts of pine needles, 30 parts of honeysuckle, 30 parts of forsythia, 25 parts of dandelion, 25 parts of houttuynia cordata and 15 parts of beam dry.

[0059] Comparative Example 2

[0060] An additive, the preparation method of this comparative example 2 is the same as the preparation method of Example 1, the only difference in the raw materials is that the raw materials do not include Belamcanda chinensis, Patrinia patriniae and Indigo naturalis. Specifically, the raw materials include 35 parts of dry pine needles, 30 parts of honeysuckle, 30 parts of forsythia, 25 parts of dandelion, 25 parts of houttuynia cordata and 5 parts of oldenlandia diffusa.

[0061] Test 1

[0062] The method for raising poultry using the additives prepared in Examples 1, 3, and 4 and Comparative Examples 1 and 2 is the same, and the feeding environment in the same batch of tests is also the same. The method for raising poultry using the additives is as follows:

[0063] When the chickens are 1-2 weeks old, the powdered additive A is added to the chicken feed at an amount of 0.5‰ by weight;

[0064] When the chickens are 3-4 weeks old, the powdered additive A is added to the chicken feed at an amount of 0.2‰ by weight;

[0065] After the chickens are 5 weeks old, the powdered additive A is added to the chicken feed at an addition amount of 0.1‰ by weight.

[0066] Table 1 Nutrient composition of chicken feed used in the experiment

[0067]

[0068]

[0069] Note: a: Premix composition (per kg feed): Copper 10 mg; Iron 60 mg; Manganese 110 mg; Selenium 0.15 mg; Iodine 0.35 mg; Zinc 50 mg; V A , 8000IU; V D3 1600IU;V E 5IU;V K ,0.5mg;V B1 3mg; V B2 5mg; Biotin 0.15mg; Folic acid, 0.25mg; Pantothenic acid 20mg; Niacin 20mg.

[0070] b: Nutritional content is calculated.

[0071] First Batch:

[0072] The experimental chickens were 2400 one-week-old Guangxi Ma chickens, which were randomly divided into 6 groups, namely Example 1 Group, Example 3 Group, Example 4 Group, Comparative Example 1 Group, Comparative Example 2 Group and Blank Group, with 400 chickens in each group. The experiment lasted for 120 days. Each group except the blank group was fed with chicken feed + corresponding additives. The blank group was fed with chicken feed without adding additives. The nutritional level of chicken feed is shown in Table 1.

[0073] Feeding and management: The experimental chickens are fed artificially throughout the whole process, and have free access to food and water; routine immunizations are performed; and a dedicated person is responsible for management.

[0074] Determination method: ① When the experimental chickens were 49 days old, 30 chickens were sampled from each group for dissection, and the relative numbers of T and B lymphocytes in the three immune organs of the experimental chickens, namely the bursa of Fabricius, spleen and thymus, were detected. The results are shown in Table 2.

[0075] ②At 120 days of age, 30 chickens were sampled from each group and slaughtered to determine the meat quality of chicken breast. The meat quality indicators included shear force, muscle moisture, intramuscular fat, muscle protein, and inosinic acid. The chicken quality was determined according to Yang Gongshe (2002).

[18] With Sun Yumin (1993)

[19] The results are shown in Table 3.

[0076] ③ The number of respiratory diseases, mortality and other related data of the experimental chickens during the breeding process were recorded, and the incidence rate of respiratory diseases and the survival rate (before slaughter) from 50 days to 120 days of age were calculated. The results are shown in Table 4.

[0077] Table 2 Relative numbers of T and B lymphocytes in immune organs

[0078]

[0079] Table 3 Chicken breast quality test results

[0080]

[0081] Table 4 Respiratory tract morbidity and survival rate

[0082]

[0083] The test results in Tables 2 to 4 show that Example 3 significantly improved chicken immunity compared to Comparative Example 1, Comparative Example 2, and the blank group, with a lower incidence of respiratory diseases and relatively good chicken quality. Example 1 also significantly improved chicken immunity compared to Example 3, with comparable chicken quality. Analysis of Example 1 revealed that the additive in Example 1, which was a frozen paste, could improve efficacy by re-crushing, but the chicken quality did not change significantly. While Example 1 did not significantly improve chicken immunity compared to Example 4, it significantly increased poultry feed intake and absorption, contributing to improved chicken quality.

[0084] Test 2

[0085] The method for raising poultry using the additives prepared in Examples 1, 3, and 4 and Comparative Examples 1 and 2 is the same, and the feeding environment in the same batch of tests is also the same. The method for raising poultry using the additives is as follows:

[0086] During the breeding process, when poultry develop respiratory diseases: mix the corresponding liquid additive B and water in a volume ratio of 1:5 to obtain a mixed solution. According to the single lesion site of the upper respiratory tract, lower respiratory tract, and air sac, each poultry is sprayed with 0.1ml of the mixed solution. If there are multiple respiratory system lesions, each additional lesion site should be increased by 0.1ml of the mixed solution per poultry, once a day, for 3-5 consecutive days.

[0087] During the atomization spraying process for poultry, the doors and windows of the poultry house and the exhaust system need to be closed before spraying. After spraying, continue to close the doors and windows and the exhaust system for 30 minutes to allow the droplets to suspend in the air of the poultry house. Ventilate the poultry house after 30 minutes.

[0088] When poultry show signs of upper respiratory tract infection, use an atomizing nozzle with a droplet diameter of 5-10μm for spraying; when poultry show signs of lower respiratory tract infection, use an atomizing nozzle with a droplet diameter of 1-4μm for spraying; when poultry show signs of air sac infection, use an atomizing nozzle with a droplet diameter of 0.1-2μm for spraying; when multiple parts of the respiratory system of poultry are infected with different pathogens, use atomizing nozzles with multiple droplet diameters for spraying based on the autopsy symptoms of dead birds.

[0089] First Batch:

[0090] In May 2022, at the poultry research and breeding base of Jiangsu Poultry Science Research Institute in Shaobo Town, Jiangdu District, Yangzhou City, 300 young Hailan laying hens aged 120 days were selected as experimental animals for artificial challenge experiments. The challenge type was infection of the poultry upper respiratory tract H9N2 subtype avian influenza virus. After the challenge, the chickens were divided into 3 groups, 100 in each group, namely the experimental group (using the liquid extract B of Example 1), the control group and the blank group. After all the experimental chickens showed symptoms, the experimental group mixed the liquid extract B and water in a volume ratio of 1:5, and then selected an atomizing nozzle with a 5μm atomized particle for spray treatment for 5 days. The control group selected a drug containing antiviral Western medicine ingredients for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are shown in Table 5 below:

[0091] Table 5

[0092] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 98 98 control group 100 89 89 Blank group 100 72 72

[0093] Second batch:

[0094] In May 2022, at the Jiangsu Poultry Science Research Institute's poultry research and breeding base in Shaobo Town, Jiangdu District, Yangzhou City, 300 120-day-old young Hailan laying hens were selected as experimental animals for artificial challenge experiments. The challenge type was infection with poultry lower respiratory tract respiratory infectious bronchitis virus. After the challenge, the chickens were divided into 3 groups, 100 in each group, namely the test group (using the liquid extract B of Example 1), the control group, and the blank group. After all the experimental chickens showed symptoms, the test group mixed the liquid extract B and water in a volume ratio of 1: 5, and then selected an atomizing nozzle with atomized particles of 1 μm for spray treatment for 5 days. The control group selected a drug containing antiviral Western medicine ingredients for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0095] Table 6

[0096] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 100 100 control group 100 97 97 Blank group 100 92 92

[0097] The third batch:

[0098] In May 2022, at the Jiangsu Poultry Science Research Institute’s poultry research and breeding base in Shaobo Town, Jiangdu District, Yangzhou City, 300 120-day-old young Hailan laying hens were selected as experimental animals for artificial challenge experiments. The challenge type was Mycoplasma gallisepticum infecting the air sac of poultry. After the challenge, the chickens were divided into 3 groups, 100 in each group, namely the experimental group (using the liquid extract B of Example 1), the control group, and the blank group. After all the experimental chickens showed symptoms, the experimental group mixed the liquid extract B and water in a volume ratio of 1:5, and then selected an atomizing nozzle with an atomized particle size of 2 μm for spray treatment for 5 days. The control group selected a drug containing anti-mycoplasma Western medicine ingredients for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0099] Table 7

[0100] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 96 96 control group 100 86 86 Blank group 100 71 71

[0101] Fourth batch:

[0102] In May 2022, at the poultry research and breeding base of Jiangsu Poultry Science Research Institute in Shaobo Town, Jiangdu District, Yangzhou City, 300 5-day-old Suqin yellow chickens in the brooding stage were selected as experimental animals for artificial virus challenge experiments. The virus challenge type was Escherichia coli that can simultaneously infect the upper respiratory tract and air sacs of poultry. After the virus challenge, the chickens were divided into 3 groups, 100 in each group, namely the experimental group (using the liquid extract B of Example 1), the control group and the blank group. After all the experimental chickens showed symptoms, the experimental group mixed the liquid extract B and water in a volume ratio of 1: 5, and then selected two atomizing nozzles with atomized particles of 4 μm and 2 μm for spray treatment for 5 days. The control group selected antibiotics containing anti-E. coli for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0103] Table 8

[0104] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 97 97 control group 100 92 92 Blank group 100 82 82

[0105] Fifth batch:

[0106] In May 2022, at the Jiangsu Poultry Science Research Institute's poultry research and breeding base in Shaobo Town, Jiangdu District, Yangzhou City, 300 5-day-old Suqin yellow chickens in the brooding stage were selected as experimental animals for artificial virus attack experiments. The virus attack type was Escherichia coli that can simultaneously infect the upper respiratory tract and air sac parts of poultry and respiratory infectious bronchitis virus that infects the lower respiratory tract. After the virus attack, the chickens were divided into 3 groups, 100 in each group, namely the test group (using the liquid extract B of Example 1), the control group and the blank group. After all the experimental chickens showed symptoms, the test group mixed the liquid extract B and water in a volume ratio of 1: 5, and then selected 3 atomizing nozzles with atomized particles of 5μm, 4μm and 2μm for spray treatment for 5 days. The control group selected antiviral ingredients containing Western medicine and anti-E. coli antibiotics for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0107] Table 9

[0108] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 95 95 control group 100 82 82 Blank group 100 31 31

[0109] Sixth batch:

[0110] In May 2022, at the poultry research and breeding base of the Jiangsu Poultry Science Research Institute in Shaobo Town, Jiangdu District, Yangzhou City, 300 young Gaoyou ducks aged 91 days were selected as experimental animals for artificial challenge experiments. The challenge type was infection of the H9N2 subtype avian influenza virus in the upper respiratory tract of poultry. After the challenge, the ducks were divided into 3 groups, 100 in each group, namely the experimental group (using the liquid extract B of Example 1), the control group and the blank group. After all the experimental ducks showed symptoms, the experimental group mixed the liquid extract B and water in a volume ratio of 1: 5, and then selected an atomizing nozzle with a 5 μm atomized particle for spray treatment for 5 days. The control group selected a drug containing antiviral Western medicine ingredients for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0111] Table 10

[0112]

[0113]

[0114] Seventh batch:

[0115] In May 2022, at the poultry research and breeding base of the Jiangsu Poultry Science Research Institute in Shaobo Town, Jiangdu District, Yangzhou City, 300 6-day-old Gaoyou ducks in the brooding stage were selected as experimental animals for artificial virus challenge experiments. The virus challenge type was Escherichia coli that can simultaneously infect the upper respiratory tract and air sacs of poultry and respiratory infectious bronchitis virus that infects the lower respiratory tract. After the virus challenge, the ducks were divided into 3 groups, 100 in each group, namely the experimental group (using the liquid extract B of Example 1), the control group and the blank group. After all the experimental ducks showed symptoms, the experimental group mixed the liquid extract B and water in a volume ratio of 1: 5, and then selected 3 atomizing nozzles with atomized particles of 5μm, 4μm and 2μm for spray treatment for 5 days. The control group selected western medicine containing antiviral ingredients and anti-E. coli antibiotics for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0116] Table 11

[0117] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 97 97 control group 100 85 85 Blank group 100 40 40

[0118] Eighth batch:

[0119] In May 2022, at the Jiangsu Poultry Science Research Institute's poultry research and breeding base in Shaobo Town, Jiangdu District, Yangzhou City, 300 young Taihu white geese aged 73 days were selected as experimental animals for artificial challenge experiments. The challenge type was infection with the H9N2 subtype avian influenza virus in the upper respiratory tract of poultry. After the challenge, the geese were divided into 3 groups, 100 in each group, namely the experimental group (using the liquid extract B of Example 1), the control group and the blank group. After all the experimental geese showed symptoms, the experimental group mixed the liquid extract B and water in a volume ratio of 1: 5, and then selected an atomizing nozzle with a 5 μm atomized particle for spray treatment for 5 days. The control group selected a drug containing antiviral Western medicine ingredients for treatment for 5 days. The blank group was not treated. After stopping the treatment, it was observed for another week. The results are as follows:

[0120] Table 12

[0121] Group Initial number (pieces) Number of surviving birds Survival rate (%) experimental group 100 98 98 control group 100 93 93 Blank group 100 84 84

[0122] The above test results show that the exquisitely formulated additives of the present invention can effectively prevent and treat various respiratory diseases of poultry during poultry breeding, reduce the use of antibiotics, and improve the quality of poultry products.

[0123] Although the embodiments of the present invention have been disclosed above, they are not limited to the applications listed in the description and implementation methods. They can be fully applied to various fields suitable for the present invention. For those familiar with the art, additional modifications can be easily implemented. Therefore, without departing from the general concept defined by the claims and the scope of equivalents, the present invention is not limited to the specific details and examples shown and described herein.

Claims

1. A poultry additive, characterized in that: The Chinese medicinal materials are composed of the following components: 35 parts of pine needles, 30 parts of honeysuckle, 30 parts of forsythia, 25 parts of dandelion, 25 parts of houttuynia, 15 parts of belamcanda vine, 15 parts of patrinia, 7 parts of indigo naturalis and 5 parts of oldenlandia diffusa; Prepared by the following preparation method: 1) Grinding the Chinese medicinal materials into 50-mesh powder; 2) Add boiling water to the powder and stir to form a paste. Freeze at -25°C for 24 hours. Then, crush the frozen paste into 50-mesh pieces and thaw at room temperature. 3) Mix the thawed mixture with 95% ethanol solution in a weight ratio of 1:1, extract at room temperature for 3 hours, repeat the filtration three times, combine the filtrates, distill under reduced pressure to remove the ethanol, and concentrate on a vacuum rotary apparatus to produce a clear paste with a relative density of 1.18-1.25; 4) Silicon dioxide powder, clear paste, cyclodextrin, and brown sugar are mixed uniformly in a weight ratio of 500:100:0.1:3 and dried to obtain powdered additive A; aged vinegar, clear paste, cyclodextrin, and brown sugar are mixed uniformly in a weight ratio of 1000:100:0.1:3 to obtain liquid additive B.

2. Use of the liquid additive B according to claim 1 in preparing a preparation for preventing and treating poultry respiratory diseases.

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