Personal care composition

Abstract

An antiperspirant and / or deodorant composition comprising 0.01% to 0.15% by weight linseed oil and 0.5% to 5.0% by weight taurine.

Description

[0001] This application is a divisional application of Chinese patent application filed on December 12, 2017, with application number "201780097388.3" and invention title "Personal Care Composition". The original application was the Chinese national phase application of international application PCT / US2017 / 065673. Technical Field

[0002] This invention relates to a personal care composition, and more particularly to an antiperspirant and / or deodorant composition comprising 0.01% to 0.15% by weight linseed oil and 0.5% to 5.0% by weight taurine. Background Technology

[0003] Personal care compositions (such as antiperspirant or deodorant compositions and dual-purpose antiperspirant-deodorant compositions) can be used to reduce body odor. For example, antiperspirant or deodorant compositions can be applied to the armpit (underarm) area to prevent or treat sweat, limit the growth of odor-causing bacteria, or apply fragrance. Furthermore, because antiperspirant or deodorant compositions are applied to the skin, they typically include ingredients that provide additional benefits to the skin, such as reduced skin irritation.

[0004] Collagen is the main structural protein of connective tissue and skin, increasing skin elasticity and firmness. Without being bound by rigid theories, it is assumed that collagen (types I, II, III, IV, and V) is synthesized into precursor molecules called procollagen. Procollagen contains additional peptide sequences, or "propeptides," at both the amino and carboxyl terms. These propeptides function to promote the winding of procollagen molecules into a triple-helix conformation ("triple-helix molecule") within the endoplasmic reticulum. During the secretion of procollagen triple-helix molecules, the propeptides cleave from the molecules as they polymerize into extracellular collagen fibrils. Therefore, it should be understood that the amount of free propeptides stoichiometrically reflects the amount of collagen molecules synthesized, and increased collagen production improves skin elasticity and firmness.

[0005] Similarly, fibrils are glycoproteins essential for the formation of connective tissue and elastic fibers in the skin, contributing to skin elasticity and firmness. For example, fibrilsin-1 is a major component in the formation of microfibrils that form a sheath surrounding amorphous elastin. Elastin helps the skin regain its original shape after being squeezed or pressed. Therefore, increased fibrilsin production also improves skin elasticity and firmness.

[0006] Therefore, there is a need for personal care compositions formulated to provide improved skin benefits, and more specifically, personal care compositions that increase the production of procollagen and fibrinogen. Summary of the Invention

[0007] This section is intended only to provide a simplified overview of some aspects of one or more embodiments of this disclosure. Other applicable areas of the invention will become apparent from the detailed description provided below. This invention is not an exhaustive summary, nor is it intended to identify key or essential elements of the teachings, nor is it intended to define the scope of this disclosure. Rather, its purpose is merely to provide one or more simplified forms of the concept as a prelude to the following detailed description.

[0008] The foregoing and / or other aspects and effects embodied in this disclosure can be achieved by an antiperspirant and / or deodorant composition comprising 0.01% to 0.15% flaxseed oil by weight of the total weight of the antiperspirant and / or deodorant composition; and 0.5% to 5.0% taurine by weight of the total weight of the antiperspirant and / or deodorant composition.

[0009] In another embodiment, the antiperspirant and / or deodorant composition comprises flaxseed oil and taurine in a weight ratio of 1:10 to 1:30.

[0010] In another embodiment, the weight ratio of flaxseed oil to taurine is 1:20.

[0011] In another embodiment, the antiperspirant and / or deodorant composition comprises 0.01% to 0.10% by weight linseed oil and 0.75% to 2.5% by weight taurine.

[0012] In another embodiment, the antiperspirant and / or deodorant composition further comprises 30% and 70% by weight of a carrier, based on the total weight of the antiperspirant and / or deodorant composition.

[0013] In another embodiment, the antiperspirant and / or deodorant composition further comprises 2.0% and 25% by weight of antiperspirant and / or deodorant active ingredients, based on the total weight of the antiperspirant and / or deodorant composition.

[0014] In another embodiment, the antiperspirant and / or deodorant composition further comprises 1.0 wt% and 7.0 wt% surfactant based on the total weight of the antiperspirant and / or deodorant composition.

[0015] In another embodiment, the antiperspirant and / or deodorant composition further comprises 0.1% and 10% emollients by weight, based on the total weight of the antiperspirant and / or deodorant composition.

[0016] In another embodiment, the antiperspirant and / or deodorant composition further includes a fragrance.

[0017] In another embodiment, the antiperspirant and / or deodorant composition further includes preservatives and / or antioxidants.

[0018] The foregoing and / or other aspects and effects embodied in this disclosure can also be achieved by a method for increasing the production of at least one of fibrils and procollagen in the skin, comprising applying an antiperspirant and / or deodorant composition to the skin, wherein the antiperspirant and / or deodorant composition comprises 0.01% to 0.15% linseed oil by weight of the total weight of the antiperspirant and / or deodorant composition; and 0.5% to 5.0% taurine by weight of the total weight of the antiperspirant and / or deodorant composition.

[0019] In another embodiment, the antiperspirant and / or deodorant composition comprises flaxseed oil and taurine in a weight ratio of 1:10 to 1:30.

[0020] The foregoing and / or other aspects and effects embodied in this disclosure can also be achieved by a method for increasing the production of at least one of fibrils and procollagen in the skin, comprising applying an antiperspirant and / or deodorant composition to the skin in an amount sufficient to increase the production of at least one of fibrils and procollagen.

[0021] The foregoing and / or other aspects and effects embodied in this disclosure can also be achieved by using antiperspirant and / or deodorant compositions to increase the production of at least one of fibrinogen and procollagen in the skin. Detailed Implementation

[0022] Reference will now be made in detail to various embodiments disclosed herein. Embodiments are described below to provide a more complete understanding of the components, methods, compositions, and apparatus disclosed herein. Any examples given are intended to be illustrative and not restrictive. However, it will be apparent to those skilled in the art that the invention can be practiced without these specific details. In other instances, well-known methods, procedures, and components have not been described in detail so as not to unnecessarily obscure aspects of the embodiments.

[0023] Throughout the specification and claims, unless the context clearly specifies otherwise, the following terms shall have the meaning explicitly relevant herein. As used herein, phrases such as “in some embodiments” and “in one embodiment” do not necessarily refer to the same embodiment, although they may be the same. Similarly, as used herein, the phrases “in another embodiment” and “in some embodiments” do not necessarily refer to different embodiments, although they may be the same. As described below, various embodiments can be readily combined without departing from the scope or spirit of this disclosure.

[0024] As used herein, unless the context explicitly specifies otherwise, the term "or" is an inclusive operator and is equivalent to the term "and / or". Unless the context explicitly specifies otherwise, the term "based on" is not exclusive and allows for basing on other factors not described. In the specification, the statement "at least one of A, B, and C" includes embodiments containing: A, B, or C; multiple instances of A, B, or C; or combinations of A / B, A / C, B / C, A / B / B / B / B / C, A / B / C, etc. Furthermore, throughout the specification, the meanings of "a / an" and "described" include a plurality of references. The meaning of "in" includes both "in" and "on".

[0025] It should also be understood that while the terms “first,” “second,” etc., may be used herein to describe various elements, these elements should not be limited by these terms. These terms are used only to distinguish one element from another. For example, without departing from the scope of the invention, a first object, component, or step may be referred to as a second object, component, or step, and similarly, a second object, component, or step may be referred to as a first object, component, or step. The first object, component, or step and the second object, component, or step are each object, component, or step, but they should not be considered as the same object, component, or step. It should be further understood that, when used in this specification, the terms “inclueds / including” and / or “comprises / comprising” specify the presence of the stated features, steps, operations, elements, and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, elements, components, and / or groups thereof. Furthermore, as used herein, the term “if” may be understood, depending on the context, to mean “when,” “in,” “in response to determining,” or “in response to detecting.”

[0026] Unless otherwise stated, all physical properties defined below were measured at 20°C to 25°C.

[0027] When any numerical range is mentioned herein, such a range is understood to include every number and / or fraction between the minimum and maximum values ​​of the range, as well as the endpoints. For example, a range of 0.5–6.0% would explicitly include all intermediate values, such as 0.6%, 0.7%, and 0.9%, up to including 5.95%, 5.97%, and 5.99%, and so on. Unless the context explicitly specifies otherwise, this also applies to every other range of numerical characteristics and / or elements set forth herein.

[0028] Furthermore, all numerical values ​​are specified as “approximate” or “about” and take into account experimental errors and biases that would be anticipated by one of ordinary skill in the art. It should be understood that all numerical values ​​and ranges disclosed herein are approximate values ​​and ranges, whether or not the word “approximate” is used in conjunction with them.

[0029] Unless otherwise specified, all percentages and quantities expressed herein and elsewhere in this specification shall be understood as weight percentages. The given quantities are based on the effective weight of the material.

[0030] Regarding the procedures, methods, techniques, and workflows according to some embodiments, some operations in the procedures, methods, techniques, and workflows disclosed herein may be combined and / or the order of some operations may be changed.

[0031] As skin ages, the production of collagen and elastin slows down, leading to wrinkles and loss of skin elasticity. Enhancing collagen and elastin production can help reduce signs of skin aging. The inventors have unexpectedly discovered that a mixture of linseed oil (FSO) and taurine has a synergistic effect on the production of fibrils and procollagen in the skin. Therefore, this disclosure provides a personal care composition comprising a synergistic combination of linseed oil and taurine, formulated to enhance the production of fibrils and procollagen in the skin. In some embodiments, the personal care composition may embody an antiperspirant and / or deodorant composition or a dual antiperspirant-deodorant composition. In other embodiments, the personal care composition may embody a skin wash or body wash.

[0032] Antiperspirant and / or deodorant compositions can be provided as liquids or gels. For example, an antiperspirant and / or deodorant composition can be a liquid roll-on formulation. A liquid roll-on formulation can be contained in any roll-on dispenser having an applicator (e.g., a ball, roller, etc.) for applying the antiperspirant and / or deodorant composition to the skin surface.

[0033] In other embodiments, the antiperspirant and / or deodorant composition may be a solid stick composition. Solid stick compositions can be manufactured using conventional methods. For example, the ingredients of the solid stick antiperspirant and / or deodorant composition may be combined and heated to melt the components (except for inert fillers) into a molten mixture. Typically, a volatile material (such as a fragrance) is incorporated after heating to prevent evaporation. The molten mixture can then be poured into a dispenser, cooled to solidify into a solid stick, and sealed to preserve the product until use.

[0034] The antiperspirant and / or deodorant compositions disclosed herein comprise a synergistic combination of linseed oil (FSO) and taurine. In some embodiments, the synergistic combination of linseed oil and taurine is configured to enhance the production of fibrils and collagen in the skin to which the antiperspirant and / or deodorant compositions are applied.

[0035] The antiperspirant and / or deodorant composition may include from about 0.0001% by weight to about 0.15% by weight of linseed oil, based on the total weight of the composition. For example, the antiperspirant and / or deodorant composition may include amounts of linseed oil from about 0.0001% by weight to about 0.10% by weight, about 0.001% by weight to about 0.10% by weight, about 0.01% by weight to about 0.10% by weight, about 0.02% by weight to about 0.07% by weight, about 0.04% by weight to about 0.10% by weight, or about 0.05% by weight. In one embodiment, the antiperspirant and / or deodorant composition includes about 0.05% by weight of linseed oil.

[0036] Flaxseed oil can be characterized by the amount of alpha-linolenic acid it contains. For example, in one embodiment, the flaxseed oil of this disclosure contains 50% by weight or more of alpha-linolenic acid based on the total weight of the flaxseed oil.

[0037] The antiperspirant and / or deodorant composition may include from about 0.001% by weight to about 5% by weight taurine, based on the total weight of the antiperspirant and / or deodorant composition. For example, the antiperspirant and / or deodorant composition may include from about 0.01% by weight to about 5% by weight taurine, from about 0.1% by weight to about 5% by weight taurine, from about 0.5% by weight to about 5% by weight taurine, from about 0.75% by weight to about 2.50% by weight taurine, or from about 0.75% by weight to about 1.25% by weight taurine. In one embodiment, the antiperspirant and / or deodorant composition includes about 1.0% by weight taurine.

[0038] In some embodiments, the amounts of linseed oil and taurine in the antiperspirant and / or deodorant composition may be provided in a ratio. For example, the antiperspirant and / or deodorant composition may include a 1:5 to 1:30 weight ratio of linseed oil to taurine. In other examples, the antiperspirant and / or deodorant composition may include a 1:10 to 1:30 weight ratio of linseed oil to taurine, a 1:5 to 1:25 weight ratio of linseed oil to taurine, or a 1:10 to 1:25 weight ratio of linseed oil to taurine. In one embodiment, the antiperspirant and / or deodorant composition may include a 1:10 to 1:20 weight ratio of linseed oil to taurine. For example, the ratio of linseed oil to taurine in the antiperspirant and / or deodorant composition may be 1:10, 1:15, 1:20, 1:25, or 1:30. In one embodiment, the ratio of linseed oil to taurine in the antiperspirant and / or deodorant composition is approximately 1:20.

[0039] In addition to the combination of linseed oil and taurine, antiperspirant and / or deodorant compositions may also include additional components. For example, an antiperspirant and / or deodorant composition may include antiperspirant and / or deodorant active ingredients, carriers, and surfactants. The antiperspirant and / or deodorant composition may also include optional ingredients such as emollients, fragrances, preservatives, antioxidants, colorants, and emulsifiers.

[0040] Antiperspirant and / or deodorant compositions may include one or more carriers or solvents. For example, antiperspirant and / or deodorant compositions may be provided in an oil-in-water emulsion form using water as a carrier. In other embodiments, the carrier may include other cosolvents miscible with water. However, in various preferred embodiments, the carrier consists of water only or substantially water, for example, a carrier consisting of at least 99% water.

[0041] In one embodiment, the amount of the carrier in the antiperspirant and / or deodorant composition is the amount that makes 100% of the composition after all ingredients (including any optional ingredients) are added to the composition. For example, the antiperspirant and / or deodorant composition may include at least 20%, at least 30%, at least 40%, at least 50%, at least 60%, at least 70%, at least 80%, or at least 90% of a carrier, based on the total weight of the antiperspirant and / or deodorant composition. In other examples, the antiperspirant composition includes about 30% to about 70% of water or about 40% to about 60% of water. In a preferred embodiment, the antiperspirant and / or deodorant composition includes about 57% of water, based on the total weight of the antiperspirant and / or deodorant composition.

[0042] Antiperspirant and / or deodorant compositions may include one or more antiperspirant active ingredients. The antiperspirant active ingredients may be selected to be compatible with or maintain the specific characteristics of other components in the antiperspirant and / or deodorant composition. For example, in some embodiments, the antiperspirant active ingredients are selected to maintain the overall pH of the antiperspirant and / or deodorant composition. The antiperspirant active ingredients may include at least one of aluminum hydroxychloride, aluminum chloride, and aluminum zirconium. In a preferred embodiment, the antiperspirant active ingredient includes aluminum chloride.

[0043] Antiperspirant and / or deodorant compositions may include an effective amount of antiperspirant active ingredient. As used herein, the expression or term "effective amount" may refer to an amount of antiperspirant active ingredient sufficient to elicit a response (e.g., biological, medical, etc.) when applied to the skin. For example, an antiperspirant and / or deodorant composition may include an amount of antiperspirant active ingredient that effectively reduces sweat flow in the armpit area. In other instances, an antiperspirant and / or deodorant composition may include an amount of antiperspirant active ingredient that effectively reduces odor or acts as an antibacterial agent.

[0044] In some embodiments, the antiperspirant and / or deodorant composition comprises from about 2% to about 25% by weight of antiperspirant active ingredient, based on the total weight of the antiperspirant and / or deodorant composition. Alternatively, the antiperspirant and / or deodorant composition may comprise from about 5% to about 20% by weight or from about 10% to about 15% by weight of antiperspirant active ingredient. For example, in a preferred embodiment, the antiperspirant and / or deodorant composition comprises about 12% by weight of aluminum chloride.

[0045] Antiperspirant and / or deodorant compositions may include one or more deodorant active ingredients. In various embodiments, the deodorant active ingredients are selected to be compatible with or maintain the specific characteristics of other components in the antiperspirant and / or deodorant composition. For example, in some embodiments, the deodorant active ingredients are selected to maintain the overall pH of the antiperspirant and / or deodorant composition. In other examples, the deodorant active ingredients are selected to be soluble in a carrier.

[0046] The deodorant active ingredient may include at least one of the following: alum, potassium aluminum sulfate, zinc oxide, ethylhexylglycerin, oteninidine hydrochloride, zinc citrate, zinc pyrithione, and silver compounds. For example, the deodorant active ingredient may include potassium aluminum sulfate or potassium aluminum sulfate crystals. In various embodiments, the deodorant active ingredient is completely dissolved in a carrier.

[0047] Antiperspirant and / or deodorant compositions may include an effective amount of deodorant active ingredient. For example, the antiperspirant and / or deodorant composition may include from about 2% to about 25% by weight of deodorant active ingredient based on the total weight of the composition. In other examples, the antiperspirant and / or deodorant composition may include from about 10% to about 20% by weight or from about 8% to about 16% by weight of deodorant active ingredient. In a preferred embodiment, the antiperspirant and / or deodorant composition includes about 12% by weight of deodorant active ingredient.

[0048] Antiperspirant and / or deodorant compositions may include one or more surfactants. The surfactants may be selectively chosen to provide sufficient viscosity to the antiperspirant and / or deodorant composition. The surfactants may also be selected to enable the dissolution of other components in the antiperspirant and / or deodorant composition. The surfactants may be further selected to resist degradation in low pH environments. For example, one or more surfactants may include at least one of the following: stearyl alcohol ether-2, stearyl alcohol ether-4, stearyl alcohol ether-6, stearyl alcohol ether-7, cetearyl alcohol ether-2, cetearyl alcohol ether-3, cetearyl alcohol ether-4, cetearyl alcohol ether-5, stearyl alcohol ether-21, stearyl alcohol ether-10, stearyl alcohol ether-11, stearyl alcohol ether-13, stearyl alcohol ether-15, stearyl alcohol ether-20, cetearyl alcohol ether-6, cetearyl alcohol ether-7, cetearyl alcohol ether-8, cetearyl alcohol ether-9, cetearyl alcohol ether-10, cetearyl alcohol ether-11, and cetearyl alcohol ether-12. In a preferred embodiment, one or more surfactants include stearyl alcohol ether-20 and stearyl alcohol ether-2.

[0049] In some embodiments, the antiperspirant and / or deodorant composition may include from about 1% to about 7% by weight of a surfactant, based on the total weight of the antiperspirant and / or deodorant composition. For example, the antiperspirant and / or deodorant composition may include from about 2% to about 6% by weight of a surfactant. In a preferred embodiment, the antiperspirant composition may include about 3.5% by weight of a surfactant. For example, the antiperspirant and / or deodorant composition may include about 1.2% by weight of stearyl ether-20 and about 2.3% by weight of stearyl ether-2 as surfactants.

[0050] Antiperspirant and / or deodorant compositions may include one or more emollients. For example, an antiperspirant and / or deodorant composition may include any desired amount of a non-volatile emollient to achieve the desired emollient effect. Emollients are known in the art and are used to impart a soothing effect to the skin. Categories of non-volatile emollients include non-silicone and silicone emollients. Non-volatile non-silicone emollients include C12-15 alkyl benzoates. Non-volatile silicone emollients may be polyether siloxanes, polyalkylaryl siloxanes, or polyether siloxane copolymers. Non-limiting examples of emollients can be found in U.S. Patent No. 6,007,799. Examples include, but are not limited to, PPG-14 butyl ether, PPG-15 stearyl ether, PPG-3 myristyl ether, stearyl alcohol, stearic acid, glyceryl monoricinoleate, isobutyl palmitate, glyceryl monostearate, isohexadecanyl stearate, sulfated animal fat, oleyl alcohol, propylene glycol, isopropyl laurate, mink oil, sorbitan stearate, hexadecyl alcohol, hydrogenated castor oil, stearyl stearate, hydrogenated soybean glyceryl ester, isopropyl isostearate, hexyl laurate, dimethyl tridecanoate, decyl oleate, diisopropyl adipate, dibutyl sebacate, diisopropyl sebacate, 2-ethylhexyl palmitate, isononyl isononanoate, isodecanyl isononanoate, isotriadecyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl stearate, di(2-ethylhexyl) adipate, and di-(2-ethylhexyl) succinate. ) esters, isopropyl myristate, isopropyl palmitate, isopropyl stearate, octacosanol, butyl stearate, glyceryl monostearate, polyethylene glycol, oleic acid, triethylene glycol, lanolin, castor oil, acetylated lanolin alcohol, acetylated lanolin, petrolatum, isopropyl lanolin, fatty acids, mineral oil, butyl myristate, isostearic acid, palmitic acid, PEG-23 oleyl ether, oleic acid oleyl alcohol ester, isopropyl linoleate, Hexadecyl lactate, lauryl lactate, myristyl lactate, quaternized hydroxyalkyl lactate, glucosamine, vegetable oil, isodecanyl oleate, isostearyl pentanoate, myristyl myristate, ethoxymyristyl oleyl alcohol, diethylene stearate, ethylene glycol monostearate, myristyl stearate, isopropyl lanolinate, paraffin, glycyrrhizic acid, alkyl benzoate, hydroxyethyl stearamide, and hydrogenated polyisobutylene.

[0051] In one embodiment, the emollient may be selected from linear silicones, cyclic silicones, hydrocarbons, polyhydroxy alcohols having more than one carbon atom, liquid or solid polyalkylene glycols containing a polypropylene glycol (PPG) moiety and capped with an alkyl ether, and combinations thereof. In another embodiment, the emollient is a non-volatile silicone, such as dimethylpolysiloxane or a longer-chain dimethylpolysiloxane.

[0052] The antiperspirant and / or deodorant composition may include from about 0.1% to about 10% emollient based on the total weight of the composition. For example, the antiperspirant and / or deodorant composition may include from about 1% to about 5% emollient or from about 2% to about 4% emollient.

[0053] Antiperspirant and / or deodorant compositions may include one or more preservatives. Preservatives can improve the antimicrobial properties of the antiperspirant and / or deodorant composition to extend shelf life or prevent spoilage. Preservatives can also enhance the functional characteristics of the antiperspirant and / or deodorant composition. For example, preservatives can enhance the deodorant or emollient effects of the antiperspirant and / or deodorant composition.

[0054] The preservatives may include, but are not limited to, at least one of the following: phenoxyethanol, butylated hydroxytoluene (BHT), ethylenediaminetetraacetic acid (EDTA), octanoyl ethylene glycol, ethylhexylglycerin, citric acid, benzoic acid, lactic acid, and combinations thereof.

[0055] Antiperspirant and / or deodorant compositions may include an effective amount of preservative. For example, an antiperspirant and / or deodorant composition may include an amount of preservative that effectively reduces spoilage of the antiperspirant and / or deodorant composition during storage or use.

[0056] In some embodiments, the antiperspirant and / or deodorant composition may optionally include one or more fragrances. If a scented product is desired, then a variety of fragrances may be used in the antiperspirant and / or deodorant composition. For example, any fragrance suitable for personal care purposes may be incorporated as a non-essential ingredient into the antiperspirant and / or deodorant composition.

[0057] Example

[0058] Various aspects of this disclosure can be further understood by referring to the following examples. These examples are illustrative and not intended to limit the embodiments thereof. Table 1 illustrates basic roll-on antiperspirant compositions. The basic roll-on antiperspirant compositions in Table 1 are used to produce three comparative roll-on antiperspirant compositions in Tables 2 and 3, which incorporate different amounts of linseed oil and taurine according to embodiments of this disclosure.

[0059] Table 2 illustrates comparative measurements of fibrin-1 and procollagen concentrations of three comparative roll-on antiperspirant compositions relative to the base roll-on antiperspirant compositions in Table 1 and untreated samples, as measured by reconstructed skin tissue cultures.

[0060] Table 3 illustrates the comparative measurements of collagen I concentration in three comparative roll-on antiperspirant compositions relative to untreated samples, as measured by monolayer skin cultures.

[0061] Table 1

[0062]

[0063] To test each of the compositions in Table 2 on a full-thickness human skin equivalent model (EFT-400, available from MATTEK Corp., Ashland, MA) as follows: Standardized tissue samples (EFT-400) were placed in 6-well culture plates containing 1 ml of freshly prepared culture medium. 30 μL of each composition (control composition and compositions 1–3) was uniformly added to the top of each tissue sample, with some samples left untreated. The tissue samples were incubated at 37°C for 60 minutes, and the culture medium sample (supernatant) was collected and stored at -80°C for later testing. After incubation, the tissue samples were washed with phosphate-buffered saline (PBS) to remove the compositions and then transferred to new culture plates containing 1 ml of fresh culture medium.

[0064] To assess fibrin-1 and procollagen production, human fibrin-1 (FBN1) (CSB-E 13141h, CUSABIO) and procollagen type I C peptide (PIP) (MK101, TAKARA) were tested using an ELISA kit in supernatant culture samples collected at 1 hour and 48 hours. Tests were performed in triplicate, and the data in Table 2 represent the average of the three tests.

[0065] Table 2

[0066]

[0067]

[0068] As shown in Table 2, the combination of flaxseed oil and taurine in composition 3 exhibits a synergistic effect on the production of fibrin-1 and procollagen.

[0069] Each of the compositions in Table 3 was tested on human dermal fibroblasts (Thermo Fisher Scientific, Gaithersburg, MD) as follows: Human dermal fibroblasts were seeded in 6-well plates and grown to approximately 80% confluence. 1 mL of each composition was added to each well, in triplicate. The cells were then incubated at 37°C and 5% CO2 for 24 hours, and the supernatant was collected and collagen I release was analyzed. Collagen I release from the supernatant was measured using the COL1A1 ELISA kit (MyBioSource, San Diego, CA). The mean collagen I release for each composition was calculated and is shown in Table 3. The data in Table 3 represent the average of three tests.

[0070] Table 3

[0071]

[0072] As shown in Table 3, compared to the individual effects of taurine and flaxseed oil, the combination of taurine and flaxseed oil exhibits a synergistic effect in promoting collagen I production.

[0073] Therefore, as shown in Tables 2-3, the inventors have unexpectedly discovered a novel antiperspirant and / or deodorant composition that enhances the production of fibrin-1 and procollagen and can provide anti-aging skin benefits by increasing skin elasticity and firmness.

[0074] This disclosure has been described with reference to exemplary embodiments. Although a limited number of embodiments have been shown and described, those skilled in the art will recognize that changes can be made to these embodiments without departing from the principles and spirit of the foregoing specific embodiments. This disclosure is intended to be construed as including all such modifications and changes, provided they fall within the scope of the appended claims or their equivalents.

Claims

1. A personal care composition comprising: Based on the total weight of the personal care composition, 0.01% to 0.10% flaxseed oil; and Based on the total weight of the personal care composition, 0.75% to 2.5% taurine, The personal care composition described herein contains flaxseed oil and taurine in a weight ratio of 1:10 to 1:

30. The personal care composition described herein is embodied as a skin wash or body wash.

2. The personal care composition according to claim 1, wherein the weight ratio of flaxseed oil to taurine is 1:

20.

3. The personal care composition according to claim 1, comprising: 0.02% to 0.07% by weight flaxseed oil; and Taurine, 0.75% to 1.25% by weight.

4. The personal care composition according to any one of the preceding claims, further comprising 30% to 70% by weight of a carrier based on the total weight of the personal care composition.

5. The personal care composition according to any one of claims 1 to 3, further comprising 2.0% to 25% by weight of a personal care active substance based on the total weight of the personal care composition.

6. The personal care composition according to any one of claims 1 to 3, further comprising 1.0 wt% to 7.0 wt% surfactant based on the total weight of the personal care composition.

7. The personal care composition according to any one of claims 1 to 3, further comprising 0.1% to 10% by weight of emollient based on the total weight of the personal care composition.

8. The personal care composition according to any one of claims 1 to 3, further comprising a fragrance.

9. The personal care composition according to any one of claims 1 to 3, further comprising a preservative and / or an antioxidant.

10. Use of a personal care composition, characterized in that... The personal care composition is used to manufacture a pharmaceutical composition for increasing the production of at least one of human fibrinogen-1 and procollagen type I C peptide in the skin, comprising: The personal care composition is applied to the skin, wherein the personal care composition comprises: Based on the total weight of the personal care composition, 0.01% to 0.10% flaxseed oil; and Based on the total weight of the personal care composition, 0.75% to 2.5% taurine, The personal care composition described herein is embodied as a skin wash or body wash.

11. The use according to claim 10, wherein the personal care composition comprises flaxseed oil and taurine in a weight ratio of 1:10 to 1:

30.

12. Use of a personal care composition, characterized in that... The personal care composition is used to manufacture a pharmaceutical composition for increasing the production of at least one of human fibrin-1 and procollagen type I C peptide in the skin, comprising applying the personal care composition according to any one of claims 1 to 7 to the skin in an amount sufficient to increase the production of at least one of human fibrin-1 and procollagen type I C peptide.

13. Use of a personal care composition according to any one of claims 1 to 9, characterized in that... The personal care composition is used to manufacture a pharmaceutical composition for increasing the production of human fibrin-1 and procollagen type I C peptide.

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