A physical sunscreen composition with skin barrier repair function and its preparation method
By using physical sunscreen compositions with skin barrier repair in sunscreen, the problem of existing sunscreen degradation after skin barrier damage is solved, and the effect of efficient sunscreen and skin barrier repair is achieved.
Patent Information
- Application Number
- CN202311274000.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-09-28
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2043-09-28
AI Technical Summary
After the skin barrier is damaged, existing sunscreen is difficult to effectively protect the sun and repair the skin barrier, resulting in dry stratum corneum, reduced intercellular lipids, and reduced use effect.
A physical sun protection composition with skin barrier repair function is adopted, including composite oils, composite plant extracts, composite hyaluronic acid, triethoxyoctylsilane, titanium dioxide, stearic acid, 1,3-propylene glycol, glycerol, glycerol octanoate, vitamin E, sodium palmitoyl proline and water, through reasonable composition distribution ratio and preparation method, a sun protection complex with repair and sun protection effect is formed.
It achieves high sun protection value, which can effectively protect the sun and repair the skin barrier, promote cell differentiation and reproduction, improve microbial flora imbalance on the surface of the skin, maintain skin moisture, and enhance the skin feeling and continuous effect of the use of sunscreen complex.
Abstract
Description
Technical Field
[0001] The present invention relates to the field of sunscreen compositions, and in particular to a method for preparing a physical sunscreen composition having a skin barrier repairing effect. Background Art
[0002] The skin barrier includes microbial barriers, physical barriers, chemical barriers, pigment barriers, neural barriers and immune barriers. The formation of these barriers plays an extremely important role in skin health and maintaining human homeostasis. Skin barrier damage is a key cause and common accompanying symptom of certain skin diseases.
[0003] After the skin barrier is damaged, the skin will cause itching, redness and other discomfort when exposed to sunlight. The damaged skin barrier causes the stratum corneum to become dry and fragile, and the intercellular lipids to decrease, resulting in a decrease in the effectiveness of sunscreens on the market. Therefore, a physical sunscreen composition with skin barrier repairing effect is proposed. Summary of the invention
[0004] In view of this, the present invention proposes a method for preparing a physical sunscreen composition with skin barrier repairing effect to solve the above problems.
[0005] The technical solution of the present invention is achieved in this way:
[0006] A physical sunscreen composition with a skin barrier repairing effect, comprising the following components by weight: 3-4 parts of composite oil, 0.4-0.6 parts of composite plant extract, 0.2-0.25 parts of composite hyaluronic acid, 0.2-0.3 parts of triethoxycaprylylsilane, 1-1.25 parts of titanium dioxide, 0.3-0.4 parts of stearic acid, 1.5-1.8 parts of 1,3-propylene glycol, 0.6-0.8 parts of glycerol, 0.8-1.2 parts of glyceryl caprylate, 0.03-0.05 parts of vitamin E, 0.05-0.08 parts of sodium palmitoyl proline and 25-30 parts of water;
[0007] The composite oil comprises olive oil, phytosterol and jojoba seed oil in a mass ratio of 6.5-8.5:1-3:10-12;
[0008] The composite plant extract comprises, by weight, 2-4 parts of long-capsule jute leaf extract, 1-3 parts of houttuynia cordata extract, 10-13 parts of purslane extract, 4-6 parts of centella asiatica extract, 9-12 parts of barley extract and 1-3 parts of white water lily extract.
[0009] Furthermore, the composite hyaluronic acid comprises, by weight, 5-7 parts of sodium hyaluronate, 7-10 parts of sodium hyaluronate cross-linked polymer, 2-4 parts of hyaluronic acid, 13-15 parts of hydrolyzed hyaluronic acid and 11-14 parts of hydrolyzed sodium hyaluronate.
[0010] Furthermore, the purslane extract is prepared by fermenting with Lactobacillus rhamnosus, and the barley extract is prepared by fermenting with lactic acid bacteria.
[0011] Furthermore, the preparation method of the purslane extract is as follows: purslane is dried and then crushed to obtain purslane powder, the purslane powder is added to water at a solid-liquid ratio of 1g:15-20mL, and chamomile powder is added to water at a solid-liquid ratio of 2g:15-20mL to obtain a fermentation mixture, 3-5% of Lactobacillus rhamnosus is added according to the mass of the fermentation mixture, fermented at 35-40°C for 36-40h, centrifuged at 500-700r / min for 15-20min, the supernatant is collected, and freeze-dried to obtain the purslane extract.
[0012] Furthermore, the preparation method of the barley extract comprises the following steps: crushing barley to obtain barley powder, adding the barley powder to an ethanol solution at a solid-liquid ratio of 1 g: 15-20 mL to obtain a fermentation mixture, adding 1-1.5% lactic acid bacteria according to the mass of the fermentation mixture, fermenting at 35-40° C. for 45-50 hours, centrifuging at 750-850 r / min for 15-20 minutes, collecting the supernatant, and freeze-drying to obtain the barley extract.
[0013] Furthermore, the volume concentration of the ethanol solution is 15-25%.
[0014] Furthermore, the method for preparing the physical sunscreen composition having skin barrier repairing effect comprises the following steps:
[0015] S1: Mix the raw materials of composite sodium hyaluronate, add triethoxycaprylylsilane, titanium dioxide, stearic acid, 1,3-propylene glycol and glycerin to disperse, and prepare phase A;
[0016] S2: adding the raw materials of the composite plant extract into water and mixing, adding glyceryl caprylate, vitamin E, and sodium palmitoyl proline into a pot and mixing, to prepare phase B;
[0017] S3: Mix phase A and phase B, perform shear emulsification, and obtain a finished product.
[0018] Furthermore, in step S1, the raw materials of the composite sodium hyaluronate are mixed by adding the composite sodium hyaluronate into water at 60-70°C at a material-liquid ratio of 1 g: 20-25 mL, stirring at 200-250 r / min for 15-20 min, and then stirring at 120-150 r / min for 10-14 min, and the dispersion is performed by using 30-40 kHz ultrasound for 10 min.
[0019] Furthermore, in step S2, the raw material of the composite plant extract is added into water and stirred at 120-140 r / min for 5-8 min, and glyceryl caprylate, vitamin E, and sodium palmitoyl proline are added into the pot and stirred at 170-190 r / min for 3-5 min.
[0020] Furthermore, in step S3, the shear emulsification is performed at 10000-15000 r / min for 3-4 times, each time for 2-3 minutes.
[0021] Compared with the prior art, the present invention has the following beneficial effects:
[0022] The sunscreen compound prepared by the present invention has a high sun protection value and can play a good sunscreen role. The sunscreen compound of the present invention has the ability to promote cell differentiation and reproduction, and achieves the effect of repairing the skin barrier. In the present invention, the purslane extract adopts Lactobacillus rhamnosus to extract the effective ingredients in purslane. After research, it is found that adding chamomile powder to the fermentation extraction of purslane can improve the moisturizing, repairing and anti-inflammatory effects of the sunscreen compound. In the present invention, the composite plant extracts are reasonably compounded to target the causes of damaged skin barrier so that the sunscreen compound can improve the imbalance of microbial flora on the skin surface, regulate the skin barrier function, and maintain skin moisture. The reasonable proportion of the components of the present invention can improve the skin feel and sustained effect of the sunscreen compound.
[0023] In view of the fact that the skin barrier is damaged, the stratum corneum is dry and fragile, and the intercellular lipids are reduced, the effective ingredients (compound oils, compound plant extracts) in the sunscreen complex are difficult to penetrate into the bottom layer of the skin. In the present invention, sodium hyaluronate, sodium hyaluronate cross-linked polymer, hyaluronic acid, hydrolyzed hyaluronic acid and hydrolyzed sodium hyaluronate are used to form composite sodium hyaluronate. Through the reasonable compounding of the five components, the stratum corneum is repaired, thereby achieving the effect of promoting the penetration of effective ingredients into the bottom layer of the skin. The composite sodium hyaluronate can form a protective film on the skin surface to reduce water loss. DETAILED DESCRIPTION
[0024] In order to better understand the technical content of the present invention, specific embodiments are provided below to further illustrate the present invention.
[0025] Unless otherwise specified, the experimental methods used in the embodiments of the present invention are all conventional methods.
[0026] Unless otherwise specified, the materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial sources.
[0027] Houttuynia cordata extract, Centella asiatica extract, Corchorus olitorii leaf extract and Nymphea alba flower extract used in the present invention
[0028] Example 1
[0029] The following components are weighed in parts by weight: 3 parts of composite oil, 0.4 parts of composite plant extract, 0.2 parts of composite hyaluronic acid, 0.2 parts of triethoxycaprylylsilane, 1 part of titanium dioxide, 0.3 parts of stearic acid, 1.5 parts of 1,3-propylene glycol, 0.6 parts of glycerol, 0.8 parts of glyceryl caprylate, 0.03 parts of vitamin E, 0.05 parts of sodium palmitoyl proline and 25 parts of water; the composite oil comprises olive oil, phytosterol and jojoba seed oil in a mass ratio of 6.5:1:10; in parts by weight, the composite plant extract consists of 2 parts of long capsule jute leaf extract, 1 part of houttuynia cordata extract, 10 parts of purslane extract, 4 parts of Centella asiatica extract, 9 parts of barley extract and 1 part of white water lily extract; the composite hyaluronic acid consists of 5 parts of sodium hyaluronate, 7 parts of sodium hyaluronate cross-linked polymer, 2 parts of hyaluronic acid, 13 parts of hydrolyzed hyaluronic acid and 11 parts of hydrolyzed sodium hyaluronate.
[0030] The preparation method of purslane extract comprises the following steps: drying purslane and then crushing it to obtain purslane powder, adding purslane powder into water at a solid-liquid ratio of 1 g:15 mL, adding chamomile powder into water at a solid-liquid ratio of 2 g:15 mL to obtain a fermentation mixture, adding 3% of Lactobacillus rhamnosus according to the mass of the fermentation mixture, fermenting at 35°C for 36 hours, centrifuging at 500 r / min for 15 minutes, collecting the supernatant, and freeze-drying to obtain the purslane extract.
[0031] The barley was crushed to obtain barley powder, and the barley powder was added to an ethanol solution with a volume concentration of 15% at a solid-liquid ratio of 1g:15mL to obtain a fermentation mixture, and 1-1.5% lactic acid bacteria was added according to the mass of the fermentation mixture. The mixture was fermented at 35°C for 45h, centrifuged at 750r / min for 15min, the supernatant was collected, and freeze-dried to obtain a barley extract.
[0032] A method for preparing a physical sunscreen composition having a skin barrier repairing effect comprises the following steps:
[0033] S1: The raw materials of composite sodium hyaluronate are mixed by adding composite sodium hyaluronate into water at 60°C according to a material-liquid ratio of 1g:20mL, stirring at 200r / min for 15min, then stirring at 120r / min for 10min, adding triethoxycaprylylsilane, titanium dioxide, stearic acid, 1,3-propylene glycol and glycerin, and dispersing them by 30kHz ultrasound for 10min to obtain phase A;
[0034] S2: Add the raw materials of the composite plant extract into water and stir at 120 r / min for 5 min, add glyceryl caprylate, vitamin E and sodium palmitoyl proline into the pot and stir at 170 r / min for 3 min to obtain phase B;
[0035] S3: Mix phase A and phase B, and treat at 10000 r / min for 3 times, each time for 2 min, to obtain a finished product.
[0036] Example 2
[0037] The following components were weighed in parts by weight: 4 parts of composite oil, 0.6 parts of composite plant extract, 0.25 parts of composite hyaluronic acid, 0.3 parts of triethoxycaprylylsilane, 1.25 parts of titanium dioxide, 0.4 parts of stearic acid, 0.8 parts of 1,3-propylene glycol, 0.8 parts of glycerol, 1.2 parts of glyceryl caprylate, 0.05 parts of vitamin E, 0.08 parts of sodium palmitoyl proline and 30 parts of water; the composite oil was composed of 8.5:3:12 in a mass ratio. The invention relates to a novel hyaluronic acid composition comprising olive oil, phytosterols and jojoba seed oil; the composite plant extract comprises, by weight, 4 parts of long capsule jute leaf extract, 3 parts of houttuynia cordata extract, 13 parts of purslane extract, 6 parts of centella asiatica extract, 12 parts of barley extract and 3 parts of white water lily extract; the composite hyaluronic acid comprises 7 parts of sodium hyaluronate, 10 parts of sodium hyaluronate cross-linked polymer, 4 parts of hyaluronic acid, 15 parts of hydrolyzed hyaluronic acid and 14 parts of hydrolyzed sodium hyaluronate.
[0038] The preparation method of purslane extract comprises the following steps: drying purslane and then crushing it to obtain purslane powder, adding purslane powder into water at a solid-liquid ratio of 1 g: 20 mL, adding chamomile powder into water at a solid-liquid ratio of 2 g: 20 mL to obtain a fermentation mixture, adding 3-5% of Lactobacillus rhamnosus according to the mass of the fermentation mixture, fermenting at 40°C for 40 hours, centrifuging at 700 r / min for 20 minutes, collecting the supernatant, and freeze-drying to obtain the purslane extract.
[0039] The barley was crushed to obtain barley powder, and the barley powder was added to an ethanol solution with a volume concentration of 25% at a solid-liquid ratio of 1 g:20 mL to obtain a fermentation mixture. 1.5% lactic acid bacteria was added according to the mass of the fermentation mixture, and the mixture was fermented at 40°C for 50 hours, centrifuged at 850 r / min for 20 minutes, the supernatant was collected, and freeze-dried to obtain a barley extract.
[0040] A method for preparing a physical sunscreen composition having a skin barrier repairing effect comprises the following steps:
[0041] S1: The raw materials of composite sodium hyaluronate are mixed by adding composite sodium hyaluronate into water at 70°C at a material-liquid ratio of 1g:25mL, stirring at 250r / min for 20min, then stirring at 150r / min for 14min, adding triethoxycaprylylsilane, titanium dioxide, stearic acid, 1,3-propylene glycol and glycerin, and dispersing by 40kHz ultrasound for 10min to obtain phase A;
[0042] S2: Add the raw materials of the composite plant extract into water and stir at 140 r / min for 8 min, add glyceryl caprylate, vitamin E and sodium palmitoyl proline into the pot and stir at 190 r / min for 5 min to obtain phase B;
[0043] S3: Mix phase A and phase B, and treat at 15000 r / min for 4 times, each time for 3 min, to obtain a finished product.
[0044] Example 3
[0045] The following components were weighed in parts by weight: 3.5 parts of composite oil, 0.5 parts of composite plant extract, 0.23 parts of composite hyaluronic acid, 0.25 parts of triethoxycaprylylsilane, 1.125 parts of titanium dioxide, 0.35 parts of stearic acid, 1.65 parts of 1,3-propylene glycol, 0.7 parts of glycerol, 1 part of glyceryl caprylate, 0.04 parts of vitamin E, 0.065 parts of sodium palmitoyl proline and 30 parts of water; the composite oil includes olive oil in a mass ratio of 7:2:11. , phytosterols and jojoba seed oil; in terms of weight, the composite plant extract consists of 3 parts of long-capsule jute leaf extract, 2 parts of houttuynia cordata extract, 11.5 parts of purslane extract, 5 parts of Centella asiatica extract, 10.5 parts of barley extract and 2 parts of white water lily extract; the composite hyaluronic acid consists of 6 parts of sodium hyaluronate, 8.5 parts of sodium hyaluronate cross-linked polymer, 23 parts of hyaluronic acid, 134 parts of hydrolyzed hyaluronic acid and 12.5 parts of hydrolyzed sodium hyaluronate.
[0046] The preparation method of purslane extract comprises the following steps: drying purslane and then crushing it to obtain purslane powder, adding purslane powder into water at a solid-liquid ratio of 1 g: 15-20 mL, adding chamomile powder into water at a solid-liquid ratio of 2 g: 20 mL to obtain a fermentation mixture, adding 4% of Lactobacillus rhamnosus according to the mass of the fermentation mixture, fermenting at 38° C. for 338 h, centrifuging at 600 r / min for 20 min, collecting the supernatant, and freeze-drying to obtain the purslane extract.
[0047] The barley was crushed to obtain barley powder, and the barley powder was added to an ethanol solution with a volume concentration of 20% at a solid-liquid ratio of 1 g:20 mL to obtain a fermentation mixture. 1.25% lactic acid bacteria was added according to the mass of the fermentation mixture, and the mixture was fermented at 40°C for 48 hours, centrifuged at 800 r / min for 20 minutes, the supernatant was collected, and freeze-dried to obtain a barley extract.
[0048] A method for preparing a physical sunscreen composition having a skin barrier repairing effect comprises the following steps:
[0049] S1: The raw materials of composite sodium hyaluronate are mixed by adding composite sodium hyaluronate into water at 65°C according to a material-liquid ratio of 1g:25mL, stirring at 230r / min for 20min, then stirring at 130r / min for 12min, adding triethoxycaprylylsilane, titanium dioxide, stearic acid, 1,3-propylene glycol and glycerin, and dispersing by 35kHz ultrasound for 10min to obtain phase A;
[0050] S2: Add the raw materials of the composite plant extract into water and stir at 130 r / min for 6.5 min, add glyceryl caprylate, vitamin E and sodium palmitoyl proline into the pot and stir at 180 r / min for 4 min to obtain phase B;
[0051] S3: Mix phase A and phase B, and treat at 13000 r / min for 3 times, each time for 3 minutes, to obtain a finished product.
[0052] Comparative Example 1
[0053] On the basis of Example 3, commercially available purslane (PORTULACA OLERACEA) extract and barley (HORDEUM VULGARE) extract were used for preparation.
[0054] Comparative Example 2
[0055] On the basis of Example 3, the dosage of the composite plant extract was adjusted to: 1 part of Jute chinensis leaf extract, 1 part of Houttuynia cordata extract, 1 part of Portulaca oleracea extract, 1 part of Centella asiatica extract, 0.5 part of barley extract and 0.5 part of White Water Lily extract.
[0056] Comparative Example 3
[0057] On the basis of Example 3, the composition of the raw materials was adjusted, specifically: the following components were weighed in parts by weight: 3.5 parts of composite oil, 0.5 parts of composite plant extract, 0.23 parts of composite hyaluronic acid, 0.25 parts of nano zinc oxide, 1.125 parts of titanium dioxide, 0.35 parts of aluminum hydroxide, 1.65 parts of 1,3-propylene glycol, 0.7 parts of glycerol, 1 part of cyclopentasiloxane, 0.04 parts of ethylhexylglycerol, 0.065 parts of sodium palmitoyl proline, 0.2 parts of sorbitan octanoate and 30 parts of water; The composite oil comprises olive oil, phytosterol and jojoba seed oil in a mass ratio of 7:2:11; in terms of weight, the composite plant extract comprises 3 parts of long-capsule jute leaf extract, 2 parts of houttuynia cordata extract, 11.5 parts of purslane extract, 5 parts of Centella asiatica extract, 10.5 parts of barley extract and 2 parts of white water lily extract; the composite hyaluronic acid comprises 6 parts of sodium hyaluronate, 8.5 parts of sodium hyaluronate cross-linked polymer, 23 parts of hyaluronic acid, 134 parts of hydrolyzed hyaluronic acid and 12.5 parts of hydrolyzed sodium hyaluronate.
[0058] Test Example 1
[0059] 1. The sunscreen complexes of Examples 1-3 and Comparative Examples 1-3 were used for efficacy tests, and the tests were conducted in accordance with the human body test in the "Technical Specification for Safety of Cosmetics". The SPF value of the sunscreen was tested using a sun protection factor tester (model: SPF 290AS).
[0060] 2. Cultivate normal human epidermal keratinocytes (NHEK) in KGM medium, collect cells with trypsin, and plate NHEK cells at 3×10 4 The cells were inoculated into a 96-well plate overnight, and the sunscreen complexes of Example 3 and Comparative Examples 1-3 were added at a concentration of 40 μg / mL. The cells were cultured for 3 days. After the culture was completed, the culture medium was removed, PBS buffer was added, and the cells were cultured for 3 h. 100 μL of 2-propanol was added, and the absorbance was detected at 570 nm to calculate the blue formazan.
[0061] Epidermal keratinocyte proliferation promotion rate = A / B × 100%
[0062] A: The amount of blue formazan produced in cells treated with the test sample
[0063] B: The amount of blue formazan produced in cells treated with the control group
[0064] 3. Use a skin moisture loss meter TM300 is used to detect the transepidermal water loss rate of the skin. The samples are the sunscreen complexes of Example 3 and Comparative Examples 1-3. The test subjects are 40 women aged 18-40, who are randomly divided into 4 groups. The test subjects' skin will show redness, stinging and itching reactions under sunlight. The sunscreen complexes of Example 3 and Comparative Examples 1-3 are applied to the face respectively, and outdoor activities are carried out normally. The TEWL value is detected after 4 hours, and the average value is calculated. The experimental results are characterized by the reduction value of the transepidermal water loss rate, which is calculated by subtracting the transepidermal water loss rate before application from the transepidermal water loss rate after 4 hours.
[0065] Table 1 SPF values of sunscreen complexes of Examples 1-3 and Comparative Examples 1-3
[0066] name Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Comparative Example 3 SPF 55.3 54.8 57.1 49.2 51.6 52.9
[0067] Table 2 Epidermal keratinocyte proliferation promotion rate of sunscreen complexes of Example 3 and Comparative Examples 1-3
[0068] name Example 3 Comparative Example 1 Comparative Example 2 Comparative Example 3 Epidermal keratinocyte proliferation promotion rate (%) 143.6 125.7 134.9 138.2
[0069] Table 3 TEWL values of sunscreen complexes of Example 3 and Comparative Examples 1-3
[0070] name Example 3 Comparative Example 1 Comparative Example 2 Comparative Example 3 TEWL reduction value (%) 7.68 5.33 5.92 6.41
[0071] The experimental results show that the sunscreen complex prepared by the present invention has a high sun protection value and can play a good sunscreen role. Combined with the experimental data analysis of Table 2-3, the sunscreen complex of the present invention has the ability to promote cell differentiation and reproduction, and achieves the effect of repairing the skin barrier. Comparative Example 1 changes the preparation method of purslane extract and barley extract. In the present invention, purslane extract uses Lactobacillus rhamnosus to extract the effective ingredients in purslane. After research, it is found that adding chamomile powder to the fermentation extraction of purslane can improve the moisturizing, repairing and anti-inflammatory effects of the sunscreen complex. In Comparative Example 2, the dosage of the composite plant extract is adjusted. In the present invention, the composite plant extract is reasonably compounded to target the causes of damaged skin barrier so that the sunscreen complex can improve the imbalance of microbial flora on the skin surface, regulate the skin barrier function, and maintain skin moisture. Comparative Example 3 changes the components in the raw materials. The reasonable proportion of the components of the present invention can improve the skin feel and sustained effect of the sunscreen complex.
[0072] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims
1. A physical sunscreen composition with skin barrier repairing effect, characterized in that: The invention comprises the following components by weight: 3-4 parts of composite oil, 0.4-0.6 parts of composite plant extract, 0.2-0.25 parts of composite hyaluronic acid, 0.2-0.3 parts of triethoxycaprylylsilane, 1-1.25 parts of titanium dioxide, 0.3-0.4 parts of stearic acid, 1.5-1.8 parts of 1,3-propylene glycol, 0.6-0.8 parts of glycerol, 0.8-1.2 parts of glyceryl caprylate, 0.03-0.05 parts of vitamin E, 0.05-0.08 parts of sodium palmitoyl proline and 25-30 parts of water; The composite oil comprises olive oil, phytosterol and jojoba seed oil in a mass ratio of 6.5-8.5:1-3:10-12; The composite plant extract comprises, by weight, 2-4 parts of long capsule jute leaf extract, 1-3 parts of houttuynia cordata extract, 10-13 parts of purslane extract, 4-6 parts of centella asiatica extract, 9-12 parts of barley extract and 1-3 parts of white water lily extract; In parts by weight, the composite hyaluronic acid comprises 5-7 parts of sodium hyaluronate, 7-10 parts of sodium hyaluronate cross-linked polymer, 2-4 parts of hyaluronic acid, 13-15 parts of hydrolyzed hyaluronic acid and 11-14 parts of hydrolyzed sodium hyaluronate; The purslane extract is prepared by fermentation with Lactobacillus rhamnosus, and the barley extract is prepared by fermentation with lactic acid bacteria; The preparation method of the purslane extract comprises the following steps: drying and then crushing the purslane to obtain purslane powder, adding the purslane powder into water at a solid-liquid ratio of 1 g: 15-20 mL, adding chamomile powder into water at a solid-liquid ratio of 2 g: 15-20 mL to obtain a fermentation mixture, adding 3-5% of Lactobacillus rhamnosus according to the mass of the fermentation mixture, fermenting at 35-40° C. for 36-40 h, centrifuging at 500-700 r / min for 15-20 min, collecting the supernatant, and freeze-drying to obtain the purslane extract.
2. The physical sunscreen composition with skin barrier repairing effect according to claim 1, characterized in that: The preparation method of the barley extract comprises the following steps: crushing barley to obtain barley powder, adding the barley powder to an ethanol solution at a solid-liquid ratio of 1 g:15-20 mL to obtain a fermentation mixture, adding 1-1.5% lactic acid bacteria according to the mass of the fermentation mixture, fermenting at 35-40° C. for 45-50 hours, centrifuging at 750-850 r / min for 15-20 minutes, collecting the supernatant, and freeze-drying to obtain the barley extract.
3. The physical sunscreen composition with skin barrier repairing effect according to claim 2, characterized in that: The volume concentration of the ethanol solution is 15-25%.
4. The method for preparing the physical sunscreen composition having skin barrier repairing effect according to any one of claims 1 to 3, characterized in that: The following steps are involved: S1: Mix the raw materials of composite hyaluronic acid, add triethoxycaprylylsilane, titanium dioxide, stearic acid, 1,3-propylene glycol and glycerin to disperse, and prepare phase A; S2: adding the raw materials of the composite plant extract into water and mixing, adding glyceryl caprylate, vitamin E, and sodium palmitoyl proline into a pot and mixing, to prepare phase B; S3: Mix phase A and phase B, perform shear emulsification, and obtain a finished product.
5. The method for preparing the physical sunscreen composition having skin barrier repairing effect according to claim 4, characterized in that: In step S1, the raw materials of the composite hyaluronic acid are mixed by adding the composite hyaluronic acid into water at 60-70°C at a material-liquid ratio of 1g:20-25mL, stirring at 200-250r / min for 15-20min, and then stirring at 120-150r / min for 10-14min. The dispersion is performed by using 30-40kHz ultrasound for 10min.
6. The method for preparing the physical sunscreen composition having skin barrier repairing effect according to claim 4, characterized in that: In step S2, the raw material of the composite plant extract is added into water and stirred at 120-140 r / min for 5-8 min, and glyceryl caprylate, vitamin E and sodium palmitoyl proline are added into the pot and stirred at 170-190 r / min for 3-5 min.
7. The method for preparing the physical sunscreen composition having skin barrier repairing effect according to claim 4, characterized in that: In step S3, the shear emulsification is performed at 10000-15000 r / min for 3-4 times, each time for 2-3 min.
Citation Information
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