Liquid inlet mechanism and analyser
By employing a design combining a pump and two three-way valves in the analyzer's liquid inlet mechanism, the high cost problem in existing technologies has been solved, achieving a low-cost liquid inlet effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHENZHEN COMEN MEDICAL INSTR
- Filing Date
- 2023-09-21
- Publication Date
- 2026-05-19
AI Technical Summary
Existing analyzer inlet mechanisms are costly due to the use of numerous pumps.
A liquid inlet mechanism is adopted, including a sampling component, a first cleaning component, and a valve design. The sampling component, reaction cup, and stirring element are cleaned by a first pump combined with two three-way valves, reducing the use of pumps.
It reduces the overall cost of the liquid inlet mechanism and analyzer, and achieves cleaning of multiple components by sharing pumps and valves, avoiding the additional construction cost of pumps.
Smart Images

Figure CN117169539B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the technical field of medical devices, and more particularly to a liquid inlet mechanism and an analyzer. Background Technology
[0002] Currently, the liquid injection mechanism in analyzers generally includes sample injection, diluent injection, and liquid injection for cleaning the sample and diluent injection actuators such as sampling needles. It also includes cleaning solution injection. After the sample and diluent are discharged into the reaction cup, the agitator stirs the mixture. Then, the reaction cup and agitator need to be cleaned by the liquid injection mechanism. There are many types of liquid injection, and a large number of pumps are used for liquid injection, resulting in high costs. Summary of the Invention
[0003] In view of this, the present invention provides a liquid inlet mechanism and an analyzer to solve the technical problem that the existing liquid inlet mechanisms are costly due to the use of a large number of pumps.
[0004] To solve the above-mentioned technical problems, the first technical solution adopted by the present invention is as follows:
[0005] A liquid inlet mechanism, the liquid inlet mechanism comprising:
[0006] A sampling assembly for delivering diluent and sample to the reaction vessel;
[0007] The first cleaning assembly includes a first container, a first pump, a first valve, a second valve, a first cleaning needle, and a cleaning tank. The first container contains a first cleaning liquid. The first valve has a first inlet, a first outlet, and a second outlet. The second valve has a second inlet, a third outlet, and a fourth outlet. The first inlet is connected to the pump outlet of the first pump. The first outlet is connected to the sampling assembly and is used to clean the sampling assembly. The second outlet is connected to the second inlet. The third outlet is connected to the first cleaning needle, which is used to clean the reaction cup. The fourth outlet is connected to the cleaning tank, which is used to clean the stirring element. The first pump can pump the first cleaning liquid in the first container into the first inlet.
[0008] In some embodiments of the liquid inlet mechanism, the sampling component includes:
[0009] First sampling needle;
[0010] The first suction and discharge component is connected to the first sampling needle and is used to draw up the sample through the first sampling needle and discharge the sample into the reaction cup;
[0011] And a second suction and discharge component, which is connected to the first suction and discharge component so as to be connected to the first sampling needle through the first suction and discharge component; the second suction and discharge component is used to draw up the diluent and discharge the diluent into the reaction cup.
[0012] The first cleaning assembly further includes a third valve, a first cleaning pipeline, and a second cleaning pipeline. The third valve has a third inlet, a fifth outlet, and a sixth outlet. The third inlet is connected to the first outlet. The fifth outlet is connected to the second suction / discharge component through the first cleaning pipeline. One end of the second cleaning pipeline is connected to the sixth outlet, and the other end is able to be opposite to the outer wall of the first sampling needle. The third valve enables the fifth outlet or the sixth outlet to be connected to the third inlet.
[0013] In some embodiments of the liquid inlet mechanism, the second suction / discharge member is connected to the first suction / discharge member via a connecting pipe. The liquid inlet mechanism also includes a valve body, which is disposed in the connecting pipe and is used to control the opening and closing of the connecting pipe.
[0014] In some embodiments of the liquid inlet mechanism, the first cleaning assembly further includes a second container, a third drain pump, and a fourth drain pump. The second container is capable of receiving waste liquid generated by the first cleaning assembly during the cleaning of the first sampling needle, the reaction cup, and the stirring element.
[0015] The third drain pump is connected to the first cleaning needle and can drain the waste liquid in the reaction cup to the second container through the first cleaning needle. The fourth drain pump is connected to the cleaning tank and is used to drain the waste liquid in the cleaning tank to the second container.
[0016] In some embodiments of the liquid inlet mechanism, the liquid inlet mechanism further includes a first swab and a first drain pump. The first swab is capable of accommodating the tip of the first sampling needle. The end of the second cleaning line away from the third valve is connected to the first swab so as to clean the outer wall of the first sampling needle by injecting the first cleaning liquid into the first swab. The first drain pump is used to discharge the waste liquid generated by the first swab to the second container.
[0017] In some embodiments of the liquid inlet mechanism, the liquid inlet mechanism further includes a third suction and discharge component and a second sampling needle, wherein the third suction and discharge component is connected to the second sampling needle and is used to draw reagents through the second sampling needle and discharge the reagents into the reaction cup;
[0018] The first cleaning assembly further includes a fourth valve, a second pump, a third cleaning line, and a fourth cleaning line. The fourth valve has a fourth inlet, a seventh outlet, and an eighth outlet. The fourth inlet is connected to the first container. The seventh outlet is connected to the third suction / discharge member through the first cleaning line. One end of the fourth cleaning line is connected to the eighth outlet, and the other end is able to be opposite to the outer wall of the second sampling needle. The fourth valve enables the seventh outlet or the eighth outlet to be connected to the fourth inlet. The second pump is used to pump the first cleaning liquid in the first container into the fourth valve.
[0019] In some embodiments of the liquid inlet mechanism, the liquid inlet mechanism further includes a second swab and a second drain pump. The second swab is capable of accommodating the tip of the second sampling needle. The end of the fourth cleaning line away from the fourth valve is connected to the second swab so as to clean the outer wall of the second sampling needle by injecting the first cleaning liquid into the second swab. The second drain pump is used to discharge the waste liquid generated by the second swab into the second container.
[0020] In some embodiments of the liquid inlet mechanism, the liquid inlet mechanism further includes a second cleaning assembly, which includes a third container, a third pump, a second cleaning needle, and a fifth drain pump. The third container contains a second cleaning liquid, the third pump is used to pump the second cleaning liquid into the second cleaning needle, the second cleaning needle is used to clean the reaction cup, and the fifth drain pump is connected to the second cleaning needle and is used to discharge waste liquid from the reaction cup through the second cleaning needle.
[0021] In some embodiments of the liquid inlet mechanism, the liquid inlet mechanism further includes a wiping element and a sixth drain pump. The wiping element is used to wipe the inner wall of the reaction cup to remove any residue remaining on the inner wall of the reaction cup. The sixth drain pump can discharge the liquid in the wiping element by suction.
[0022] To solve the above-mentioned technical problems, the second technical solution adopted by the present invention is as follows:
[0023] An analyzer includes the liquid inlet mechanism described in the above embodiments.
[0024] Implementing the embodiments of the present invention will have at least the following beneficial effects:
[0025] The above-mentioned liquid inlet mechanism, when applied to the analyzer, enables both itself and the analyzer to achieve a low-cost technical effect. Specifically, the liquid inlet mechanism of the present invention, through a first pump combined with two three-way valves (first valve and second valve), can use the first cleaning liquid in the first container to clean the sampling component, reaction cup, or stirring element through the first valve and second valve respectively. Thus, the cleaning of the sampling component, reaction cup, or stirring element can be achieved with one pump and two valves, thereby solving the technical problem of high cost caused by the use of a large number of pumps in existing liquid inlet mechanisms. Attached Figure Description
[0026] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0027] Figure 1 This is a schematic diagram of the liquid inlet mechanism in one embodiment.
[0028] in:
[0029] 1. First sampling needle; 2. First suction / discharge component; 3. Second suction / discharge component;
[0030] 401. Third valve; 402. First container; 403. First pump; 404. First cleaning line; 405. Second cleaning line; 406. Fourth valve; 407. Second pump; 408. Third cleaning line; 409. Fourth cleaning line; 410. First valve; 411. First cleaning needle; 412. Third drain pump; 413. Second valve; 414. Cleaning tank; 415. Fourth drain pump;
[0031] 5. Valve body; 6. Second container; 71. First swab; 72. First drain pump; 81. Third suction / discharge component; 82. Second sampling needle; 83. Second swab; 84. Second drain pump; 91. Third container; 92. Third pump; 93. Second cleaning needle; 94. Fifth drain pump; 101. Wiping component; 102. Sixth drain pump. Detailed Implementation
[0032] To facilitate understanding of the present invention, a more complete description will be given below with reference to the accompanying drawings. Preferred embodiments of the invention are shown in the drawings. However, the invention can be implemented in many other different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a thorough and complete understanding of the disclosure of the invention.
[0033] It should be noted that when a component is said to be "fixed to" another component, it can be directly attached to the other component or there may be an intervening component. When a component is said to be "connected to" another component, it can be directly connected to the other component or there may be an intervening component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.
[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0035] like Figure 1 As shown, in one embodiment of the liquid inlet mechanism, the liquid inlet mechanism includes a sampling component and a first cleaning component. The sampling component is used to deliver diluent and sample to the reaction cup, and the stirrer is used to stir the mixture in the reaction cup. The first cleaning component includes a first container 402, a first pump 403, a first valve 410, a second valve 413, a first cleaning needle 411, and a cleaning tank 414. The first container 402 contains a first cleaning liquid. The first valve 410 has a first inlet, a first outlet, and a second outlet. The second valve 413 has a second inlet, a third outlet, and a fourth outlet. The first inlet is connected to the pump outlet of the first pump 403, and the first outlet is connected to the sampling component and used to clean the sampling component. The second outlet is connected to the second inlet, and the third outlet is connected to the first cleaning needle 411. The first cleaning needle 411 is used to clean the reaction cup. The fourth outlet is connected to the cleaning tank 414, and the cleaning tank 414 is used to clean the stirrer. The first pump 403 can pump the first cleaning liquid in the first container 402 into the first inlet.
[0036] In this embodiment, the liquid inlet mechanism uses a first pump 403 combined with two three-way valves, a first valve 410 and a second valve 413, to allow the first cleaning liquid in the first container 402 to be used to clean the sampling component, the reaction cup, or the stirring element through the first valve 410 and the second valve 413 respectively. Thus, the cleaning of the sampling component, the reaction cup, or the stirring element can be achieved with one pump and two valves, thereby solving the technical problem of high cost caused by the use of a large number of pumps in existing liquid inlet mechanisms.
[0037] In one embodiment of the liquid inlet mechanism, the sampling assembly includes a first sampling needle 1, a first suction / discharge member 2, and a second suction / discharge member 3. The first suction / discharge member 2 is connected to the first sampling needle 1 and is used to draw a sample through the first sampling needle 1 and discharge the sample into a reaction cup. The second suction / discharge member 3 is connected to the first suction / discharge member 2, so that it is connected to the first sampling needle 1 through the first suction / discharge member 2. The second suction / discharge member 3 is used to draw a diluent and discharge the diluent into the reaction cup. During the process of the second suction / discharge member 3 drawing or discharging the diluent, the diluent passes through the first suction / discharge member 2. The first cleaning assembly also includes a third valve 401, a first cleaning line 404, and a second cleaning line 405. The third valve 401 has a third inlet, a fifth outlet, and a sixth outlet. The third inlet is connected to the first outlet. The fifth outlet is connected to the second suction / discharge member 3 through the first cleaning line 404. One end of the second cleaning line 405 is connected to the sixth outlet, and the other end can be opposite to the outer wall of the first sampling needle 1. The third valve 401 can connect the fifth outlet or the sixth outlet to the third inlet.
[0038] In this embodiment, the first sampling needle 1, the first suction and discharge component 2, and the second suction and discharge component 3 are connected. The first suction and discharge component 2 can draw and discharge samples through the first sampling needle 1, while the second suction and discharge component 3 is connected to the first sampling needle 1 through the first suction and discharge component 2. Thus, the second suction and discharge component 3 can draw and discharge diluent through the first sampling needle 1. On the other hand, due to the connection between the first sampling needle 1, the first suction and discharge component 2, and the second suction and discharge component 3, the inner walls of the three components can be cleaned at once through the third valve 401, the first pump 403, and the first cleaning pipeline 404. Furthermore, the third valve 401 can be switched to connect to the second cleaning pipeline 405, thereby cleaning the outer wall of the first sampling needle 1. Thus, the cleaning of the inner walls of the first sampling needle 1, the first suction and discharge component 2, and the second suction and discharge component 3, as well as the cleaning of the outer wall of the first cleaning needle 1, can be achieved through a single pump and a single valve.
[0039] Specifically, the first suction and discharge component 2 and the second suction and discharge component 3 can be syringes. The end of the second cleaning tube 405 away from the third valve 401, i.e. the outlet, can be opposite to the needle tip of the first sampling needle 1. Alternatively, the second cleaning tube 405 can be fixed, and the first sampling needle 1 can be driven to approach the outlet of the second cleaning tube 405. Or, the second cleaning tube 405 can move together with the first sampling needle 1, always maintaining a relative position.
[0040] It should be noted that the syringe of the first sampling needle 1 has a certain length. Under the adsorption of the first suction and discharge component 2 and the second suction and discharge component 3, the sample and diluent can be temporarily stored together in the syringe of the first sampling needle 1.
[0041] In one embodiment of the liquid inlet mechanism, the second suction / discharge member 3 is connected to the first suction / discharge member 2 via a connecting pipe. The liquid inlet mechanism also includes a valve body 5, which is disposed in the connecting pipe and is used to control the opening and closing of the connecting pipe.
[0042] In this embodiment, by setting the valve body 5, the functions of the first suction and discharge component 2 and the second suction and discharge component 3 can be isolated. When the first suction and discharge component 2 is sucking up and discharging the sample, the valve body 5 can be closed to prevent the sample from flowing into the second suction and discharge component 3 when the first suction and discharge component 2 is sucking up and discharging the sample. However, when the second suction and discharge component 3 is working, the valve body 5 is in the open state.
[0043] In one embodiment of the liquid inlet mechanism, the liquid inlet mechanism further includes a second container 6, a third drain pump 412, and a fourth drain pump 415. The second container 6 is capable of receiving waste liquid generated by the first cleaning assembly during cleaning of the first sampling needle 1, the first suction / discharge member 2, and the second suction / discharge member 3. The third drain pump 412 is connected to the first cleaning needle 411 and is capable of discharging waste liquid from the reaction cup into the second container 6 through the first cleaning needle 411. The fourth drain pump 415 is connected to the cleaning tank 414 and is used to discharge waste liquid from the cleaning tank 414 into the second container 6.
[0044] In this embodiment, the second container 6 can be a waste liquid tank, used to collect the waste liquid generated during cleaning. By setting the second container 6, the waste liquid can be prevented from contaminating the inside of the analyzer.
[0045] It should be noted that the waste liquid generated from cleaning the first sampling needle 1, the first suction and discharge component 2, and the second suction and discharge component 3 includes the waste liquid generated from cleaning the inner walls of the three components, the waste liquid generated from cleaning the outer wall of the first sampling needle 1, and the waste liquid generated from cleaning the reaction cup and the stirring component.
[0046] In one embodiment of the liquid inlet mechanism, the liquid inlet mechanism further includes a first swab 71 and a first drain pump 72. The first swab 71 is capable of accommodating the needle tip of the first sampling needle 1. The end of the second cleaning conduit 405 away from the third valve 401 is connected to the first swab 71 so as to clean the outer wall of the first sampling needle 1 by injecting a first cleaning liquid into the first swab 71. The first drain pump 72 is used to discharge the waste liquid generated by the first swab 71 to the second container 6.
[0047] In this embodiment, a first swab 71 is provided, which has a channel for cleaning the first sampling needle 1. The first sampling needle 1 can be inserted into the channel under the drive to clean the outer wall of the first sampling needle 1 through the first swab 71. The waste liquid generated during cleaning can be discharged into the second container 6 under the action of the first drainage pump 72.
[0048] In conjunction with the previous embodiments, in this embodiment, the first swab 71 can be in a fixed position. When cleaning is required, the needle tip of the first sampling needle 1 extends into the first swab 71. Thus, it can be understood that the second cleaning tube 405 is also fixed. Alternatively, the first swab 71 and the first sampling needle 1 can be mounted on the same frame, with the first swab 71 located on the sampling movement path of the first sampling needle 1. That is, the first sampling needle 1 needs to pass through the first swab 71 when sampling and discharging samples. After sampling, during the reset process of the first sampling needle 1, its tip can extend into the channel of the first swab 71 and be cleaned. After discharging samples, the tip can also be cleaned.
[0049] In one embodiment of the liquid inlet mechanism, the liquid inlet mechanism further includes a third suction / discharge member 81 and a second sampling needle 82. The third suction / discharge member 81 is connected to the second sampling needle 82 and is used to draw reagents through the second sampling needle 82 and discharge reagents into a reaction cup. The first cleaning assembly also includes a fourth valve 406, a second pump 407, a third cleaning line 408, and a fourth cleaning line 409. The fourth valve 406 has a fourth inlet, a seventh outlet, and an eighth outlet. The fourth inlet is connected to the first container 402. The seventh outlet is connected to the third suction / discharge member 81 through the first cleaning line 404. One end of the fourth cleaning line 409 is connected to the eighth outlet, and the other end can be opposite to the outer wall of the second sampling needle 82. The fourth valve 406 can connect the seventh outlet or the eighth outlet to the fourth inlet. The second pump 407 is used to pump the first cleaning liquid in the first container 402 into the fourth valve 406.
[0050] In this embodiment, by adding a third suction / discharge component 81 and a second sampling needle 82, the liquid inlet mechanism is combined with reagent suction / discharge, and the first cleaning component is also combined with cleaning the third suction / discharge component 81 and the second sampling needle 82. Specifically, the fourth valve 406 and the second pump 407, together with the third valve 401 and the first pump 403, form two branches branching off from the first container 402. The fourth valve 406 is also a three-way valve, just like the third valve 401. The two outlets of the fourth valve 406 are also connected to two cleaning pipelines respectively. One cleaning pipeline, namely the third cleaning pipeline 408, is used to clean the inner walls of the third suction / discharge component 81 and the second sampling needle 82, while the other cleaning pipeline, namely the fourth cleaning pipeline 409, is used to clean the outer wall of the second sampling needle 82.
[0051] For ease of understanding, the operation of the liquid inlet mechanism of the present invention is described here. Its working process is as follows: first, a diluent is collected, then a sample is collected, and then the diluent and sample in the first sampling needle tube are discharged together into the reaction cup for incubation. After incubation for a period of time, the reagent and the incubated mixture are placed in another cup for reaction and detection. After completion, the devices involved in collecting samples, diluents and reagents are cleaned inside and out.
[0052] In one embodiment of the liquid inlet mechanism, the liquid inlet mechanism further includes a second swab 83 and a second drain pump 84. The second swab 83 is capable of accommodating the needle tip of the second sampling needle 82. The end of the fourth cleaning line 409, away from the fourth valve 406, is connected to the second swab 83 to clean the outer wall of the second sampling needle 82 by injecting a first cleaning liquid into the second swab 83. The second drain pump 84 is used to discharge the waste liquid generated by the second swab 83 to the second container 6.
[0053] In this embodiment, a second swab 83 is provided, which has a channel for cleaning the second sampling needle 82. The second sampling needle 82 can be inserted into the channel under the drive to clean the outer wall of the second sampling needle 82 through the second swab 83. The waste liquid generated during cleaning can be discharged into the second container 6 under the action of the second drainage pump 84.
[0054] In conjunction with the previous embodiments, in this embodiment, the second swab 83 can be in a fixed position. When cleaning is required, the needle tip of the second sampling needle 82 extends into the second swab 83. Thus, it can be understood that the fourth cleaning tube 409 is also fixed. Alternatively, the second swab 83 and the second sampling needle 82 can be mounted on the same frame, with the second swab 83 located on the sampling movement path of the second sampling needle 82. That is, the second sampling needle 82 needs to pass through the second swab 83 during sampling and dispensing. After sampling, during the reset process of the second sampling needle 82, its tip can extend into the channel of the second swab 83 and be cleaned. After dispensing, the tip can also be cleaned.
[0055] In conjunction with the preceding embodiments, a detailed description is provided here. By setting the first valve 410, two branches can be further divided. The first valve 410 and the third valve 401 share a driving source, namely the first pump 403. When the first valve 410 connects the first inlet and the first outlet, the first pump 403 can pump the liquid in the first container 402 to the third valve 401. When the first valve 410 connects the first inlet and the second outlet, the first pump 403 can pump the liquid in the first container 402 to the first cleaning needle 411. Thus, the second cleaning needle 93, which extends into the reaction cup, can clean the reaction cup. Secondly, the first cleaning needle 411 can be a tubular structure such as a needle tube. One end is connected to the second outlet via a pipeline, and the other end is used to clean the reaction cup. The size of the opening can be adjusted to control the force of the liquid impacting the inner wall of the reaction cup. The first cleaning needle 411 also has an outlet in its middle, which is connected to the third drain pump 412 via a pipeline. When the third drain pump 412 is not running, no liquid can flow from this outlet. However, when the third drain pump 412 is running, the liquid in the reaction cup can be drawn out through the needle tip of the first cleaning needle 411. This embodiment, through this configuration, does not require an additional pump for liquid inlet, sharing the first container 402 and the first pump 403, reducing construction costs and increasing the overall functionality of the liquid inlet mechanism without a significant increase in cost. Preferably, the second container 6 can be used to receive the waste liquid discharged from the first cleaning needle 411.
[0056] Additionally, the agitator can be a stirring bar. It's understood that the agitator needs to be immersed in the mixture during stirring, so it's inevitable that it will be covered in liquid. To clean the agitator, a cleaning tank 414 is provided. When the agitator needs cleaning, it is placed in the cleaning tank 414 and rotated. The liquid used to clean the agitator in the cleaning tank 414 originates from the first container 402. A second valve 413 facilitates the connection to the cleaning tank 414, and a fourth drain pump 415 drains the waste liquid from the cleaning tank 414 after the agitator is cleaned. This embodiment also uses the first container 402 and the first pump 403, without adding an additional pump for liquid inlet, reducing construction costs. Preferably, the second container 6 can be used to receive the waste liquid discharged by the fourth drain pump 415.
[0057] In conjunction with the preceding embodiments, preferably, the number of first cleaning needles 411 is multiple and arranged in parallel.
[0058] To improve the cleanliness of the reaction cup, in one embodiment of the liquid inlet mechanism, the liquid inlet mechanism further includes a second cleaning component. The second cleaning component includes a third container 91, a third pump 92, a second cleaning needle 93, and a fifth drain pump 94. The third container 91 contains a second cleaning liquid. The third pump 92 is used to pump the second cleaning liquid into the second cleaning needle 93. The second cleaning needle 93 is used to clean the reaction cup. The fifth drain pump 94 is connected to the second cleaning needle 93 and is used to discharge the waste liquid in the reaction cup through the second cleaning needle 93.
[0059] In conjunction with the preceding embodiments, the first cleaning liquid can be deionized water, and the second cleaning liquid can be a medical device-specific detergent. By providing a second cleaning component, the inner wall of the reaction cup can be cleaned using the second cleaning liquid. When cleaning the reaction cup, the second cleaning liquid can be used first, followed by the first cleaning liquid, thus improving the cleanliness of the reaction cup. Preferably, the second container 6 can be used to receive the waste liquid discharged from the second cleaning needle 93.
[0060] To further improve the cleanliness of the reaction cup, in one embodiment of the liquid inlet mechanism, the liquid inlet mechanism further includes a wiping member 101 and a sixth drain pump 102. The wiping member 101 is used to wipe the inner wall of the reaction cup to remove any residue on the inner wall of the reaction cup. The sixth drain pump 102 can pump the liquid in the wiping member 101 into the second container 6 by suctioning the wiping member 101.
[0061] Based on the above embodiments, it is hereby explained that each drainage pump is used to discharge waste liquid into the second container 6.
[0062] This invention, by setting a first pump 403 and two three-way valves, a first valve 410 and a second valve 413, enables the switching of three functions: cleaning of the sampling needle 1, liquid inlet to the first cleaning needle 411, and liquid inlet to the cleaning tank 414. This further solves the technical problem of high cost caused by the use of a large number of pumps in existing liquid inlet mechanisms. The coordinated scheduling of the three functions can be achieved through the following steps:
[0063] The movement of a typical reaction disk is periodic. Taking the reaction disk iterating forward two cup positions in each cycle as an example, along with the periodic movement of the reaction disk, the first suction / ejection component 2, the second suction / ejection component 3, and the third suction / ejection component 81 complete the sampling and addition of the sample, diluent, and reagent. The stirring component completes the stirring action at specific times. Specifically, for one sample, the action of the first suction / ejection component 2 is completed within one cycle, the action of the second suction / ejection component 3 is completed within one cycle, the action of the first sampling needle 1 is completed within two cycles, the action of the third suction / ejection component 81 and the second sampling needle 82 is completed within one cycle, and the action of the stirring component is completed within two cycles, divided into two stages. The first stage is to stir the sample and diluent evenly, and the second stage is to further stir the above mixture and reagent evenly. The cleaning of the reaction cups is carried out in the same sequence as the periodic movement of the reaction disk, so the cleaning of the reaction cups is performed in each cycle.
[0064] It should be noted that the diluent is first drawn into the syringe of the first sampling needle 1 through the second suction and discharge device 3, and then the sample is drawn into the syringe of the first sampling needle 1 through the first suction and discharge device 2. Then the sample and diluent in the first sampling needle 1 are discharged together into the reaction cup. This is the first sampling needle 1 in two cycles. The suction and discharge action of the first suction and discharge device 2 is continuous, while the suction and discharge action of the third suction and discharge device 81 is spaced out between two different cycles of the first sampling needle 1.
[0065] When multiple samples are tested simultaneously, sampling or adding diluent, reagent collection, and stirring of different samples may all occur within the same cycle. When these actions are performed within a single cycle, the liquid inlet control steps of this invention are as follows:
[0066] S1, the second pump 407 and the fourth valve 406 are opened, and at the same time the third suction and discharge component 81 performs the corresponding action to complete the first cleaning of the second sampling needle 82.
[0067] S2. The stirrer completes the first stirring in the reaction vessel and returns to its initial position.
[0068] S3. After the first suction and discharge component 2 completes the sampling, the first sampling needle 1 is inserted, and the first valve 410 and the first pump 403 are opened to clean the outer wall of the first sampling needle 1.
[0069] S4. The third suction and discharge component 81 completes the first reagent suction. As the second sampling needle 82 is inserted, the second pump 407 is turned on to clean the outer wall of the second sampling needle 82.
[0070] S5. The first cleaning needle 411 is inserted into the reaction cup cleaning position, and the first pump 403 is turned on to perform the first reaction cup cleaning.
[0071] S6. After the first suction and discharge component 2 completes the addition of sample to the reaction cup, the first sampling needle 1 is inserted, the first valve 410 and the first pump 403 are opened to clean the outer wall of the first sampling needle 1. After the third suction and discharge component 81 completes the aspiration of the pre-diluted sample in the reaction cup, the second pump 407 is opened to clean the outer wall of the second sampling needle 82.
[0072] S7. The first cleaning needle 411 is inserted into the reaction cup cleaning position, the first pump 403 is turned on to perform the second reaction cup cleaning, and the third suction and discharge device 81 completes the addition of pre-diluted sample and reagent to the reaction cup. At the same time, the second sampling needle 82 is inserted and the second pump 407 is turned on to perform the cleaning of the outer wall of the second sampling needle 82.
[0073] S8, the second pump 407 and the fourth valve 406 are opened, and at the same time the third suction and discharge component 81 performs the corresponding action to complete the second cleaning of the second sampling needle 82.
[0074] S9. After the agitator completes its first injection in the cleaning tank 414, the second valve 413 and the first pump 403 are opened to complete the first cleaning of the agitator.
[0075] S10. Open valve body 5. The second suction and discharge component returns from its original near full-scale state to the initial position, completing the cleaning of the inner wall of the first sampling needle 1. At the same time, open the first valve 410 and the first pump 403 to clean the outer wall of the first sampling needle 1. The third suction and discharge component 81 completes the second reagent aspiration. As the second sampling needle 82 is inserted, open the second pump 407 to clean the outer wall of the second sampling needle 82.
[0076] S11, the third suction and discharge component 81 completes the third reagent suction, and the second sampling needle 82 is inserted. The second pump 407 is turned on to clean the outer wall of the second sampling needle 82.
[0077] S12. The agitator completes the second stirring in the reaction cup and returns to the initial position. The agitator completes the second needle insertion in the cleaning tank 414. The second valve 413 and the first pump 403 are opened to complete the second cleaning of the agitator.
[0078] S13. After the first sampling needle 1 completes the aspiration of the diluent, the first valve 410 and the first pump 403 are opened to clean the outer wall of the first sampling needle 1. After the third suction and discharge component 81 completes the second reagent addition in the reaction cup, the second pump 407 is opened to clean the outer wall of the second sampling needle 82.
[0079] The present invention also relates to an analyzer, including the liquid inlet mechanism in the preceding embodiments.
[0080] By employing the liquid inlet mechanism in the above embodiments, the liquid inlet mechanism has a low cost due to the use of fewer pumps, which further reduces the overall cost of the analyzer.
[0081] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0082] The above embodiments merely illustrate several implementation methods of the present invention, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this patent should be determined by the appended claims.
Claims
1. A liquid inlet mechanism, characterized in that, The liquid inlet mechanism includes: A sampling assembly for delivering diluent and sample to the reaction vessel; The first cleaning assembly includes a first container, a first pump, a first valve, a second valve, a first cleaning needle, and a cleaning tank. The first container contains a first cleaning liquid. The first valve has a first inlet, a first outlet, and a second outlet. The second valve has a second inlet, a third outlet, and a fourth outlet. The first inlet is connected to the pump outlet of the first pump. The first outlet is connected to the sampling assembly and is used to clean the sampling assembly. The second outlet is connected to the second inlet. The third outlet is connected to the first cleaning needle. The first cleaning needle is used to clean the reaction cup. The fourth outlet is connected to the cleaning tank. The cleaning tank is used to clean the stirring element. The first pump can pump the first cleaning liquid in the first container into the first inlet. The sampling component includes: First sampling needle; The first suction and discharge component is connected to the first sampling needle and is used to draw up the sample through the first sampling needle and discharge the sample into the reaction cup; And a second suction and discharge component, which is connected to the first suction and discharge component so as to be connected to the first sampling needle through the first suction and discharge component; the second suction and discharge component is used to draw up the diluent and discharge the diluent into the reaction cup. The first cleaning assembly further includes a third valve, a first cleaning pipeline, and a second cleaning pipeline. The third valve has a third inlet, a fifth outlet, and a sixth outlet. The third inlet is connected to the first outlet. The fifth outlet is connected to the second suction / discharge component through the first cleaning pipeline. One end of the second cleaning pipeline is connected to the sixth outlet, and the other end is able to be opposite to the outer wall of the first sampling needle. The third valve enables the fifth outlet or the sixth outlet to be connected to the third inlet. The first cleaning assembly further includes a second container, a third drain pump, and a fourth drain pump. The second container is capable of receiving waste liquid generated by the first cleaning assembly during the cleaning of the first sampling needle, the reaction cup, and the stirring element. The third drain pump is connected to the first cleaning needle and can drain the waste liquid in the reaction cup to the second container through the first cleaning needle. The fourth drain pump is connected to the cleaning tank and is used to drain the waste liquid in the cleaning tank to the second container. The liquid inlet mechanism further includes a first swab and a first drain pump. The first swab can accommodate the tip of the first sampling needle. The end of the second cleaning line away from the third valve is connected to the first swab so that the outer wall of the first sampling needle can be cleaned by injecting the first cleaning liquid into the first swab. The first drain pump is used to discharge the waste liquid generated by the first swab to the second container. The liquid inlet mechanism further includes a third suction and discharge component and a second sampling needle. The third suction and discharge component is connected to the second sampling needle and is used to draw the reagent through the second sampling needle and discharge the reagent into the reaction cup. The first cleaning assembly further includes a fourth valve, a second pump, a third cleaning line, and a fourth cleaning line. The fourth valve has a fourth inlet, a seventh outlet, and an eighth outlet. The fourth inlet is connected to the first container. The seventh outlet is connected to the third suction / discharge member through the first cleaning line. One end of the fourth cleaning line is connected to the eighth outlet, and the other end is able to be opposite to the outer wall of the second sampling needle. The fourth valve enables the seventh outlet or the eighth outlet to be connected to the fourth inlet. The second pump is used to pump the first cleaning liquid in the first container into the fourth valve.
2. The liquid inlet mechanism as described in claim 1, characterized in that, The second suction and discharge component is connected to the first suction and discharge component through a connecting pipe. The liquid inlet mechanism also includes a valve body, which is located in the connecting pipe and is used to control the opening and closing of the connecting pipe.
3. The liquid inlet mechanism as described in claim 1, characterized in that, The liquid inlet mechanism further includes a second swab and a second drain pump. The second swab is capable of accommodating the tip of the second sampling needle. The end of the fourth cleaning line away from the fourth valve is connected to the second swab so as to clean the outer wall of the second sampling needle by injecting the first cleaning liquid into the second swab. The second drain pump is used to discharge the waste liquid generated by the second swab into the second container.
4. The liquid inlet mechanism as described in claim 1, characterized in that, The liquid inlet mechanism further includes a second cleaning assembly, which includes a third container, a third pump, a second cleaning needle, and a fifth drain pump. The third container contains a second cleaning liquid, the third pump is used to pump the second cleaning liquid into the second cleaning needle, the second cleaning needle is used to clean the reaction cup, and the fifth drain pump is connected to the second cleaning needle and is used to discharge the waste liquid in the reaction cup through the second cleaning needle.
5. The liquid inlet mechanism as described in claim 1, characterized in that, The liquid inlet mechanism also includes a wiping element and a sixth liquid discharge pump. The wiping element is used to wipe the inner wall of the reaction cup to remove any residue on the inner wall of the reaction cup. The sixth liquid discharge pump can pump out the liquid in the wiping element by suction.
6. An analyzer, characterized in that, Includes the liquid inlet mechanism as described in any one of claims 1-5.