A composition for conditioning the intestinal tract and alleviating fatigue, and a preparation method and application thereof

Abstract

The application discloses a composition for regulating intestines and relieving fatigue, a preparation method and application thereof, and belongs to the technical field of food. The composition for regulating intestines and relieving fatigue comprises the following raw materials in parts by mass: cordyceps militaris concentrated powder 15-30 parts, hawk beak natto freeze-dried powder 10-20 parts, Chinese wolfberry powder 3-10 parts and hemp seed powder 1-8 parts. In the composition, the components have obvious synergistic effects by adopting suitable component treatment methods and adding the treated components with suitable mass parts, so that the composition can achieve excellent effects of regulating intestines and relieving fatigue. In addition, the composition can be prepared into products with different forms for regulating intestines and relieving fatigue, and the preparation method is simple and easy for actual production.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of food technology, and particularly relates to a composition for regulating intestinal tract and relieving fatigue as well as a preparation method and application thereof. BACKGROUND

[0002] Nowadays, people who often feel fatigue are not only the elderly, but also the middle-aged and young people, because the middle-aged and young people are the main laborers, and the pressure is increased due to long-term work, which will gradually evolve into chronic fatigue syndrome if not released in time, and even lead to serious diseases such as hypertension, diabetes, cerebral hemorrhage, myocardial infarction, depression, coronary heart disease and cancer. This group of people is the main productive force in China, and their work, study and life directly affect economic development and social progress, so the fatigue problem needs to be solved as soon as possible to ensure the health of the middle-aged and young people and the future development of the motherland. At present, the main functional components of the products for regulating intestinal tract and relieving fatigue on the market are caffeine, taurine, probiotics and prebiotics, and many additives are added to improve the taste and smell, but there is no substantial effect. Therefore, a convenient and effective composition for regulating intestinal tract and relieving fatigue will have a great prospect in the market.

[0003] On the other hand, with the improvement of people's quality of life, the concept of diet is also changing, and natural green food has been paid more and more attention due to the increasing demand for health and the emphasis on green health care. In the selection of health food, more attention is paid to natural and green products that have the same effect as other health products and do not produce toxic side effects during consumption. SUMMARY

[0004] The present application aims to overcome the shortcomings of the prior art and provide a composition for regulating intestinal tract and relieving fatigue which is green and healthy and has excellent effects of regulating intestinal tract and relieving fatigue as well as a preparation method and application thereof.

[0005] To achieve the above-mentioned purpose, in a first aspect, the technical solution adopted by the present application is as follows: a composition for regulating intestinal tract and relieving fatigue, which comprises the following raw materials in mass parts: Cordyceps militaris concentrated powder 15-30 parts, hawk beak natto freeze-dried powder 10-20 parts, wolfberry powder 3-10 parts, and hemp seed powder 1-8 parts.

[0006] The preparation method of the Cordyceps militaris concentrated powder is as follows: the Cordyceps militaris is crushed, water-extracted, alcohol-sedimented, concentrated and dried to obtain the Cordyceps militaris concentrated powder.

[0007] The preparation method of the chickpea natto freeze-dried powder is that chickpeas are soaked, cooked, inoculated with natto bacteria for fermentation culture, dried, and crushed to obtain the chickpea natto freeze-dried powder.

[0008] The preparation method of the wolfberry powder is that wolfberries are infiltrated with water, filtered, concentrated and dried, and crushed to obtain the wolfberry powder.

[0009] The preparation method of the hemp seed powder is that hemp seeds are crushed, water-extracted, concentrated and dried, crushed, and formulated to obtain the hemp seed powder.

[0010] The composition for regulating the intestinal tract and relieving fatigue provided by the present application adds appropriate proportions of cordyceps militaris concentrated powder, chickpea natto freeze-dried powder, wolfberry powder, and hemp seed powder, and obtains the four components through appropriate preparation methods, so that the excellent effects of the four components can be maintained, and good compounding effects among the four components can be achieved, thereby realizing excellent effects of regulating the intestinal tract and relieving fatigue.

[0011] Specifically, cordyceps militaris has high protein biological value, appropriate proportion of human amino acids, rich dietary fiber, and contains mainly unsaturated oleic acid and linoleic acid, and a variety of vitamins, and more importantly, cordyceps militaris contains a variety of bioactive components closely related to human health, such as adenosine, cordyceps polysaccharide, cordycepin, and ergosterol, cordyceps polysaccharide can relieve fatigue, anti-aging, antioxidant, anticoagulant, hypoglycemic, hypolipidemic, and improve liver function, and has significant medicinal effects; the cordyceps militaris concentrated powder prepared by the water extraction and alcohol precipitation method can maximize the pharmacological effects and blending ratio.

[0012] Chickpea is the second largest consumed bean in the world, and its yield ranks third in the world, and is one of the food bean crops with the widest cultivation area in the world; compared with soybeans, chickpea has extremely low oil content, and is rich in 18 kinds of amino acids, proteins, dietary fibers, calcium, potassium, zinc, and a variety of trace elements and vitamins required by the human body; chickpea itself has the effect of reducing three high, and has edible type, medicinal type, and dual-purpose type; the bioactive components in chickpea natto also include natto kinase, methyl naphthoquinone-7, pyridinedicarboxylic acid, polyglutamic acid, and fructan in the vitamin K2 family, and these active components are produced in the fermentation process, so that chickpea natto becomes a nutrient-rich food raw material; the present application can greatly retain and stimulate the active components in chickpea by soaking, cooking, and inoculating fermentation.

[0013] The bioactive components of the wolfberry fruit are complex, mainly including wolfberry polysaccharide, zeaxanthin, beta-carotene, betaine, flavonoids, cerebrosides and part of trace elements; the wolfberry polysaccharide is a water-soluble polysaccharide extracted from the wolfberry fruit, and is considered to be one of the main active components in the wolfberry fruit due to its many biological effects; researches show that the wolfberry polysaccharide has the effects of anti-fatigue, anti-tumor, anti-inflammatory, blood sugar reduction, blood lipid reduction, nerve protection, liver protection, eye protection and the like; the latest research finds that the wolfberry polysaccharide is a good source of prebiotics, can increase the abundance of intestinal flora, improve the level of beneficial bacteria and regulate the innate immune response; compared with the many biological activities of the wolfberry polysaccharide, the wolfberry polysaccharide has a wide application prospect and development value; the wolfberry powder is prepared by adopting the method of percolation water extraction, so that the active components can be retained to the maximum extent.

[0014] Hemp seed is also known as hemp seed, hemp seed and hemp seed, which is the fruit or seed kernel without pericarp of Cannabis sativa L. in Moraceae; it is first recorded in Shennong's Herbal Classic; it is sweet and flat, and belongs to spleen, stomach and large intestine channels, and has the effects of moistening dryness, smoothing the intestines, relieving stranguria and activating blood; modern research shows that hemp seed extract has the effects of antioxidant, anti-aging, anti-inflammatory and anti-fatigue, and can improve the learning and memory impairment of model mice with chemical drug-induced senile dementia; animal experiments and in vitro cell models confirm that hemp seed polysaccharide has the repairing effect on intestinal mucosal injury, which provides a theoretical basis for developing hemp seed extract into a natural intestinal mucosal protective regulator; the present application can ensure the good realization of the effect of hemp seed by water extraction of hemp seed and blending.

[0015] As a preferred embodiment of the composition for regulating the intestinal tract and relieving fatigue, the composition comprises the following mass parts of raw materials: cordyceps militaris concentrated powder 18-23 parts, hawk beak natto freeze-dried powder 14-15 parts, wolfberry powder 7-8 parts, hemp seed powder 4-5 parts.

[0016] As a preferred embodiment of the composition for regulating the intestinal tract and relieving fatigue, the composition comprises the following mass parts of raw materials: cordyceps militaris concentrated powder 23 parts, hawk beak natto freeze-dried powder 15 parts, wolfberry powder 8 parts, hemp seed powder 5 parts.

[0017] The inventors found that when the adding amount of the further preferred components is in the above range or even a point value, the composition has more prominent effects of regulating the intestinal tract and relieving fatigue.

[0018] As a preferred embodiment of the composition for regulating intestines and relieving fatigue, the preparation method of the cordyceps militaris concentrated powder is as follows: the cordyceps militaris is crushed to ≤20 mesh, mixed with 9-11 times of water by weight, extracted at 95-100 ℃ for 1.5-2 h twice, then filtered with a 200 mesh filter screen, the filtrate is collected, concentrated under reduced pressure, and then 2-6 times of ethanol by weight is added to the concentrated product and left for 3-6 h, then solid-liquid separation is performed, the collected solid is redissolved in water, heated to remove ethanol, and then spray dried to obtain the cordyceps militaris concentrated powder.

[0019] In the cordyceps militaris concentrated powder prepared by the preparation method, the mass percentage of polysaccharide is ≥25%, the mass percentage of cordyceps militaris is ≥0.1%, and the mass percentage of adenosine is ≥0.5%.

[0020] As a preferred embodiment of the composition for regulating intestines and relieving fatigue, the preparation method of the hawk's beak natto freeze-dried powder is as follows: the hawk's beak beans are soaked in 2-6 times of water by weight for 16-20 h, then the soaked hawk's beak beans are drained and cooked at 115-120 ℃ for 25-35 min, after cooling, 3-8% of natto bacteria by weight is inoculated into the cooled hawk's beak beans, and the hawk's beak beans are cultured at 36-42 ℃ for 24-36 h, then vacuum freeze-drying is performed at (-20)-(-40) ℃, and finally low-temperature crushing is performed to obtain the hawk's beak natto freeze-dried powder.

[0021] In the hawk's beak natto freeze-dried powder prepared by the preparation method, the number of viable bacteria is ≥3 billion CFU / g, and the mass percentage of protein is ≥20%.

[0022] As a preferred embodiment of the composition for regulating intestines and relieving fatigue, the preparation method of the wolfberry powder is as follows: the wolfberry is subjected to percolation water extraction at 95-99 ℃, then the water extraction is finished, the filtrate is collected and dried by concentration, and then crushing is performed to obtain the wolfberry powder.

[0023] In the wolfberry powder prepared by the preparation method, the mass percentage of polysaccharide is ≥35%.

[0024] As a preferred embodiment of the composition for regulating intestines and relieving fatigue, the preparation method of the hemp seed powder is as follows: the hemp seeds are crushed to a particle size of 0.5-0.7 cm, mixed with 9-11 times of water by weight, and extracted at 97-99 ℃ for 1.5-2.5 h, then the extraction liquid is concentrated under reduced pressure at a temperature of <80 ℃ and dried and crushed, then 0.3-1.0% of hemp seed oil by weight is added to the crushed product and uniformly mixed to obtain the hemp seed powder.

[0025] In the hemp seed powder prepared by the preparation method, the mass percentage of polysaccharide is ≥3.5%.

[0026] The inventors have found that when the Cordyceps sinensis concentrated powder, the hawk beak natto freeze-dried powder, the Chinese wolfberry powder and the hemp seed powder are prepared by the above method respectively, the content of the effective components in the obtained components is ensured within a certain range, and the obtained composition can achieve good compounding effects while the components exert their respective effects.

[0027] In a second aspect, the application provides a preparation method of the composition for regulating intestinal tract and relieving fatigue, which comprises the following steps: uniformly mixing the components according to the mass fraction to obtain the composition.

[0028] In a third aspect, the application provides an application of the composition for regulating intestinal tract and relieving fatigue in the preparation of a product for regulating intestinal tract and / or relieving fatigue.

[0029] As a preferred embodiment of the application, the product is in any one of the forms of powder, paste, hard capsule, soft capsule, solid beverage, liquid beverage and tablet.

[0030] In a fourth aspect, the application provides a tablet candy, which comprises the following components in mass fraction: 32-60 parts of the composition for regulating intestinal tract and relieving fatigue, 45-70 parts of sweetening agent and 0.5-2 parts of anti-caking agent.

[0031] Preferably, the sweetening agent is isomalt, and the anti-caking agent is magnesium stearate or silicon dioxide.

[0032] In a fifth aspect, the application provides a preparation method of the tablet candy, which comprises the following steps: screening the components for regulating intestinal tract and relieving fatigue through a 40-mesh sieve in an environment with a temperature of 18-26 DEG C and a relative humidity of 45-65%, collecting the undersize and mixing the undersize with the anti-caking agent and the sweetening agent to obtain the tablet candy.

[0033] Compared with the prior art, the application has the following beneficial effects:

[0034] The composition for regulating intestinal tract and relieving fatigue provided by the application can achieve excellent effects of regulating intestinal tract and relieving fatigue due to the synergistic effect of the components, and the composition can be prepared into products for regulating intestinal tract and relieving fatigue in different forms, and the preparation method is simple and easy to produce. DETAILED DESCRIPTION

[0035] In order to better illustrate the purpose, technical scheme and advantages of the application, the application will be further described below with reference to specific examples.

[0036] The reagents, methods and devices used in the present application are all conventional reagents, methods and devices in the art unless otherwise specified.

[0037] Examples 1-4 and Comparative Examples 1-8

[0038] Examples 1-4 and Comparative Examples 1-8 of the present application provide a composition for regulating intestinal tract and relieving fatigue, the content (parts by weight) of which is shown in Table 1;

[0039] Table 1

[0040]

[0041]

[0042] The preparation method of the composition for regulating intestinal tract and relieving fatigue in Example 1 is as follows:

[0043] (1) Preparation of Cordyceps militaris concentrated powder: Cordyceps militaris was ground to 20 mesh, mixed with 10 times the weight of water, and extracted at 98±2℃ for two times, each for 2h, then filtered with a 200 mesh filter screen, the filtrate was concentrated under reduced pressure, and 4 times the weight of ethanol was added to the concentrated product, then it was left to stand for 4h, followed by solid-liquid separation, the collected solids were redissolved in water, heated to remove ethanol, and finally spray dried to obtain Cordyceps militaris concentrated powder;

[0044] (2) Preparation of Faba bean Natto freeze-dried powder: Faba bean was soaked in 4 times the weight of water for 18h, then the soaked faba bean was drained and cooked at 117±2℃ for 30min, after cooling, 6% of Natto bacteria by weight was inoculated into the cooled faba bean, and cultured at 38±2℃ for 30h, then vacuum freeze-dried at -30℃, and finally low-temperature pulverized to obtain Faba bean Natto freeze-dried powder;

[0045] (3) Preparation of Medlar powder: Medlar was subjected to percolation water extraction at 97±2℃, after water extraction, the filtrate was collected and concentrated and dried, then pulverized to obtain Medlar powder;

[0046] (4) Preparation of Hemp seed powder: Hemp seed was broken to a particle size of 0.6cm, mixed with 10 times the weight of water, and extracted at 98±1℃ for 2h, then the extract was concentrated and dried under reduced pressure at a temperature of 60℃, followed by adding 0.6% of pressed hemp seed oil by weight to the pulverized product and mixing uniformly to obtain hemp seed powder;

[0047] (5) Preparation of the composition for regulating intestinal tract and relieving fatigue: the Cordyceps militaris concentrated powder, Faba bean Natto freeze-dried powder, Medlar powder and hemp seed powder prepared in steps (1)-(4) were mixed uniformly according to the weight parts in Table 1 to obtain the composition for regulating intestinal tract and relieving fatigue.

[0048] The preparation method of the intestinal regulation and fatigue relief composition in Examples 2-4 and Comparative Examples 1-4 is completely consistent with that in Example 1, and no related components are added.

[0049] Example 5

[0050] The present application provides a tablet candy, which comprises 51 parts of the intestinal regulation and fatigue relief composition in Example 1, 47.5 parts of isomalt, 1 part of magnesium stearate, and 0.5 parts of silicon dioxide.

[0051] The preparation method of the tablet candy is as follows: the intestinal regulation and fatigue relief composition in Example 1 is sieved through a 40-mesh screen in an environment with a temperature of 22±2℃ and a relative humidity of 50%, the undersize is collected and uniformly mixed with isomalt, magnesium stearate and silicon dioxide, and then tableting is performed to obtain the tablet candy.

[0052] Comparative Example 5

[0053] The present application provides an intestinal regulation and fatigue relief composition, and the only difference between the present comparative example and Example 1 is that the preparation method of the cordyceps militaris concentrated powder is different.

[0054] The preparation method of the cordyceps militaris concentrated powder in the present comparative example is as follows: cordyceps militaris is mixed with 5 times the weight of water, and extracted twice at 98±2℃ for 3 hours each time, then filtered through an 80-mesh screen, the filtrate is concentrated under reduced pressure, 3 times the amount of ethanol is added to the concentrated solution and left to stand for 3 hours, then solid-liquid separation is performed, the collected solid is redissolved in water, heated to remove ethanol, and finally spray dried to obtain the cordyceps militaris concentrated powder.

[0055] Comparative Example 6

[0056] The present application provides an intestinal regulation and fatigue relief composition, and the only difference between the present comparative example and Example 1 is that the preparation method of the hawk beak natto freeze-dried powder is different.

[0057] The preparation method of the hawk beak natto freeze-dried powder in the present comparative example is as follows: hawk beak beans are soaked in 4 times the weight of water for 10 hours, then the soaked hawk beak beans are drained and cooked at 121℃ for 20 minutes, after cooling, 2% of natto bacteria by weight is inoculated into the cooled hawk beak beans, and cultured at 33℃ for 2 days, then transferred to a refrigerator at 4℃ for maturation for 24 hours, after the culture is completed, vacuum drying is performed under reduced pressure, and finally low-temperature pulverization is performed to obtain the hawk beak natto freeze-dried powder.

[0058] Comparative Example 7

[0059] The present application provides an intestinal regulation and fatigue relief composition, and the only difference between the present comparative example and Example 1 is that the preparation method of the wolfberry powder is different.

[0060] The preparation method of wolfberry powder in the present comparative example is as follows: wolfberry is mixed with 6 times of water by weight, and extracted at 80℃ for 1.5h twice, then filtered with a 100-mesh filter screen, the filtrate is concentrated under reduced pressure and spray dried to obtain wolfberry powder.

[0061] Comparative Example 8

[0062] The present comparative example provides a composition for regulating intestinal tract and relieving fatigue, the only difference between the present comparative example and Example 1 is that the preparation method of hemp seed powder is different.

[0063] The preparation method of hemp seed powder in the present comparative example is as follows: hemp seed is mixed with 8 times of water by weight, and extracted at 85℃ for 2h twice, then filtered with a 100-mesh filter screen, the filtrate is concentrated under reduced pressure and spray dried to obtain hemp seed powder.

[0064] Effect Example 1

[0065] The present effect example verifies the intestinal tract regulating effect of the composition for regulating intestinal tract and relieving fatigue obtained in Examples 1-4 and Comparative Examples 1-8, and the intestinal tract regulating effect of the tabletted candy obtained in Example 5, which specifically comprises the following steps:

[0066] (1) Establishment of animal model: mice are orally administered with antibiotic injection solution at a dose of 4.5g / kg·bw, twice a day for 10 consecutive days, and the blank group is orally administered with normal saline at the same dose, and the model group of mice is orally administered with antibiotic injection solution at the above-mentioned dose, wherein groups 1-12 are respectively given the composition in Examples 1-4 and Comparative Examples 1-8, and are fed at a dose of 0.65g / kg / d, and group 13 is given the product in Example 5, and is fed at a dose of 1.27g / kg / d, and after 10 days, the intestinal flora of the model mice is detected; the B / E value (Bifidobacterium / E. coli) is used in medicine to evaluate the intestinal flora, if the B / E ratio is greater than 1, it indicates that the intestinal flora is in a balanced state, and if the B / E ratio is less than 1, it indicates that the intestinal flora is in an unbalanced state;

[0067] (2) The experimental mice are divided into 15 groups according to the complete random principle, and the blank group and the model group of mice are fed with the same ordinary feed, and the comparison group and the administration group are fed with the composition feed, and the living environment of all mice is kept consistent;

[0068] (3) Subsequently, the intestinal flora of the mice in the experimental groups was detected by random sampling, and the data was collected and observed after 10 days of feeding. The mice in the blank group were in good mental state, normal activity, clean and tidy hair, and no abnormalities in appearance and defecation. The mice in the model group were in poor mental state, reduced activity and slow movement, hair was sticky and lacked luster, and the skin on the back was easily visible when the mice moved. The mice had diarrhea, and the feces were loose and difficult to form. There were more feces residues near the anus. The mice in the comparative groups 1-8 were in general mental state, less active than normal mice, and the hair was slightly sticky and the luster had not fully recovered. There were no abnormalities in appearance and defecation. The mice in the example 1-5 groups were in good mental state, normal activity, clean and tidy hair, and no abnormalities in appearance and defecation. The contents of bifidobacterium and enterobacteriaceae in the mice in the groups 1-15 were further recorded, and the B / E value was calculated. The B / E value (bifidobacterium / enterobacteriaceae) is used in medicine to evaluate the condition of intestinal flora. If the B / E ratio is greater than 1, it indicates that the intestinal flora is in a balanced state. If the B / E ratio is less than 1, it indicates that the intestinal flora is in an unbalanced state. The smaller the ratio, the more serious the imbalance. The recorded data is shown in Table 2.

[0069] Table 2

[0070]

[0071]

[0072] As can be seen from Table 2, the intestinal regulation and fatigue relief composition obtained by the technical scheme of the present application has excellent effect of improving intestinal flora, and can improve the B / E value of the mice in the model group with B / E value <1 to B / E value >1, and the obtained B / E is all above 1.10, close to 1.15 of the blank group. As can be seen from Example 1 and Example 5, when the intestinal regulation and fatigue relief composition in Example 1 is used as a component of tablet candy, the improvement and maintenance effect of the tablet candy on intestinal flora is almost the same as that of the intestinal regulation and fatigue relief composition under the condition that the feeding dose of the intestinal regulation and fatigue relief composition remains unchanged. Moreover, the change range of B / E value of Example 1 and Example 5 is almost the same as that of the blank group, that is, the intestinal improvement effects of the two are similar. As can be seen from Example 1 and Comparative Examples 1-4, when any one of Cordyceps militaris concentrate powder, hawk beak natto freeze-dried powder, medlar powder and hemp seed powder is reduced, the improvement effect of the obtained product on intestinal flora is obviously decreased, and the difference in B / E value with the blank group is increased. As can be seen from Example 1 and Comparative Examples 5-8, when the four components in the present application are used but the preparation methods of the components are different, the ability of the obtained product to improve the intestine also shows a significant downward trend.

[0073] Effect Example 2

[0074] The effect example verifies the fatigue relieving effect of the intestinal tract conditioning and fatigue relieving composition obtained in the embodiment 1-4 and the comparative example 1-8 and the fatigue relieving effect of the pressed tablet candy obtained in the embodiment 5, and specifically includes the following steps:

[0075] Healthy mice are selected and randomly divided into 14 groups, all the mice are fed with ordinary feed, wherein groups 1-12 are respectively given the products in the embodiment 1-4 and the comparative example 1-8, and fed at a dose ratio of 0.65g / kg / d, group 13 is given the product in the embodiment 5, and fed at a dose ratio of 1.27g / kg / d, and the blank group mice are given normal saline, and fed at a dose ratio of 0.65g / kg / d; continuously fed for 4 weeks; first normally fed for 1 week, and then daily swimming adaptive training is carried out for 15min after the first week, the water depth of the swimming box is 30cm, and the water temperature is 25±1℃. The last week carries out the mouse weight (2g lead skin) swimming test; the time from the beginning of swimming to the head sinking into the water for 10s and unable to float out of the water is recorded as the swimming time of the mouse, and the obtained results are shown in Table 3, wherein the P value is obtained by using Prism data analysis software;

[0076] Table 3

[0077] Group Average duration (min) P Group Average duration (min) P Control 7.06±1.69 — Comparative Example 1 8.78±0.62 0.0493 Example 1 11.55±0.95 <0.0001 Comparative Example 2 8.79±0.69 0.0473 Example 2 11.02±1.14 <0.0001 Comparative Example 3 8.89±0.65 0.0302 Example 3 10.52±1.23 <0.0001 Comparative Example 4 8.93±0.71 0.0251 Example 4 10.61±1.13 <0.0001 Comparative Example 5 9.56±1.68 0.0009 Example 5 11.63±0.87 <0.0001 Comparative Example 6 9.43±1.45 0.0018 Comparative Example 7 9.31±1.61 0.0036 Comparative Example 8 9.29±1.58 0.0040

[0078] As can be seen from Table 3, the composition for regulating intestines and relieving fatigue obtained by adopting the technical scheme of the present application has excellent effect of relieving fatigue, the average duration of swimming is more than 10.52 min, compared with the average duration of the control group, the improvement range is between 49.00-64.73%, especially when the adding amount of the further preferred components is the adding amount in Examples 1-2, the effect of relieving fatigue of the obtained product is more excellent, specifically, the average duration of swimming is more than 11.02 min, compared with the average duration of the control group, the improvement range is 56.09-63.60%; as can be seen from Example 1 and Example 5, when the composition for regulating intestines and relieving fatigue in Example 1 is used as a component of the tablet candy, under the condition that the feeding dose ratio of the composition for regulating intestines and relieving fatigue is unchanged, the effect of relieving fatigue of the obtained tablet candy has almost no difference with the effect of relieving fatigue of the composition for regulating intestines and relieving fatigue; as can be seen from Example 1 and Comparative Examples 1-4, when any one of Cordyceps militaris concentrated powder, hawk beak natto freeze-dried powder, medlar powder and hemp seed powder is reduced, the effect of relieving fatigue of the obtained product is obviously decreased, compared with the average duration of swimming in Example 1, the decrease range in Comparative Examples 1-4 is 22.68-23.98%; as can be seen from Example 1 and Comparative Examples 5-8, when the four components in the present application are adopted but the preparation ways of the components are different, the effect of relieving fatigue of the obtained product also presents an obvious decreasing trend, compared with the average duration of swimming in Example 1, the decrease range in Comparative Examples 1-4 is 17.23-19.57%.

[0079] Finally, it should be noted that the above examples are used to illustrate the technical scheme of the present application, but not to limit the protection scope of the present application, although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical scheme of the present application can be modified or replaced equivalently without departing from the essence and scope of the technical scheme of the present application.

Claims

1. A composition for conditioning the intestinal tract and alleviating fatigue, characterized by comprising: The composition is composed of the following raw materials in mass parts: Cordyceps militaris concentrated powder 15-30 parts, hawk mouth natto freeze-dried powder 10-20 parts, wolfberry powder 3-10 parts, hemp seed powder 1-8 parts; The preparation method of the Cordyceps militaris concentrated powder is as follows: Cordyceps militaris is crushed to ≤20 mesh, then mixed with 9-11 times weight ratio of water, and extracted at 95-100℃ for 1.5-2h twice, then filtered with a 200 mesh filter screen, the filtrate is collected and concentrated under reduced pressure, and then 2-6 times weight ratio of ethanol is added to the concentrated product and left for 3-6h, then solid-liquid separation is performed, the collected solid is redissolved in water, heated to remove ethanol, and then spray dried to obtain the Cordyceps militaris concentrated powder; The preparation method of the hawk mouth natto freeze-dried powder is as follows: hawk mouth beans are soaked in 2-6 times weight ratio of water for 16-20h, then the soaked hawk mouth beans are drained and cooked at 115-120℃ for 25-35min, then 3-8% of Bacillus natto is inoculated into the cooled hawk mouth beans, and the mixture is cultured at 36-42℃ for 24-36h, then vacuum freeze-dried at (-20)-(-40)℃, and finally low-temperature crushed to obtain the hawk mouth natto freeze-dried powder; The preparation method of the wolfberry powder is as follows: wolfberry is subjected to percolation water extraction at 95-99℃, then filtered with an 80 mesh filter screen, the filtrate is collected and concentrated and dried, and then crushed to obtain the wolfberry powder; The preparation method of the hemp seed powder is as follows: hemp seeds are crushed to a particle size of 0.5-0.7cm, then mixed with 9-11 times weight ratio of water, and extracted at 97-99℃ for 1.5-2.5h, then the extract is concentrated and dried under reduced pressure at a temperature of <80℃, then 0.3-1.0% of pressed hemp seed oil is added to the crushed product and mixed uniformly to obtain the hemp seed powder.

2. The composition for conditioning the intestinal tract and alleviating fatigue according to claim 1, characterized by, The composition includes the following raw materials in mass parts: Cordyceps militaris concentrated powder 18-23 parts, hawk mouth natto freeze-dried powder 14-15 parts, wolfberry powder 7-8 parts, hemp seed powder 4-5 parts.

3. The composition for conditioning the intestinal tract and alleviating fatigue according to claim 1, characterized by, The composition includes the following raw materials in mass parts: Cordyceps militaris concentrated powder 23 parts, hawk mouth natto freeze-dried powder 15 parts, wolfberry powder 8 parts, hemp seed powder 5 parts.

4. The method of preparing the intestinal conditioning and fatigue alleviating composition according to any one of claims 1 to 3, wherein The preparation method includes the following steps: mixing the components uniformly according to mass parts to obtain the composition.

5. Use of the composition for regulating intestinal tract and relieving fatigue according to any one of claims 1-3 in the preparation of a product for regulating intestinal tract and / or relieving fatigue.

6. A tabletted confectionery characterized in that, The tabletted candy includes the following components in mass parts: The tabletted candy includes the following components in mass parts: the composition for regulating intestinal tract and relieving fatigue according to any one of claims 1-3 32-60 parts, sweetening agent 45-70 parts, anti-caking agent 0.5-2 parts.

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