Freeze formulation labelling apparatus

Abstract

The application belongs to the technical field of labeling, and discloses a frozen preparation labeling equipment, which comprises an operation box body, the operation box body comprises a storage box body and a labeling box body, the labeling box body is arranged on the upper layer of the storage box body, and a labeling operation table top is arranged between the labeling box body and the storage box body; a display opening is arranged on the labeling operation table top, a mounting cavity is arranged in the storage box body, a temporary storage cold box is arranged in the mounting cavity, the top of the temporary storage cold box is open, the top of the temporary storage cold box is opposite to the display opening, a first refrigeration structure is arranged in the temporary storage cold box, and the first refrigeration structure is used for temporarily storing frozen preparation products; an inlet and an outlet are arranged on the side wall of the labeling box body, the inlet allows the frozen preparation products to pass through, the hands of labeling personnel pass through the operation opening to enter and exit the labeling box body, and the labeling operation table top is used for labeling the products, so that the labeling operation of the products can be completed without the process of thawing and re-freezing the frozen preparation products, the quality and activity of the products are ensured to be not damaged, and the labeling cost is low.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of labeling, in particular to a frozen preparation labeling equipment. BACKGROUND

[0002] At the early development stage, biomolecule drugs are generally stored in a low-temperature state to provide sufficient stability and prevent degradation, avoid product aggregation and denaturation at high temperatures, and reduce activity. In particular, for some protein products, the storage temperature needs to be lower than-20℃ to ensure complete freezing of the product. For some products with poor stability, process operations (including but not limited to sample handling, sub-packaging, sampling, and preparation stirring and mixing) need to be performed in a low-temperature environment to ensure the stability of the product during the operation.

[0003] For labeling of frozen preparation products, due to the flexibility of clinical application, the frozen preparation products are not labeled in advance because the labeling time is later than the production time, and the labeling is performed according to the needs after the label is determined. After the frozen biological preparation product is frozen at low temperature, there are a large number of ice crystals on the surface of the bottle wall, which causes the label to be unable to be attached to the bottle. Even if part of the label is attached to the bottle, after the product is thawed, the ice water will also cause the label to peel off and fall off the bottle, thereby causing the information of the drug to be unclear for clinical use and leading to the occurrence of medication errors.

[0004] The current solutions include two kinds: the first kind is to thaw the frozen preparation, and then label the outer surface of the container such as a vial by using a manual or automatic labeling machine. The label used can withstand low temperatures, and then the labeled product is frozen again. However, for sensitive biomacromolecules, repeated freezing and thawing operations will affect the quality / activity of the product. Therefore, experiments need to be conducted to prove that repeated freezing and thawing operations will not affect the effectiveness and safety of the product, and then the labeling method can be used. The second kind is to establish an ultra-low temperature freezer, and personnel wearing protective devices enter the ultra-low temperature freezer to perform labeling operations. The defects are that the personnel wear too many devices, the operation is inconvenient, the energy consumption of the freezer is serious, and the operation cost of the freezer is high.

[0005] Therefore, there is an urgent need for a frozen preparation labeling equipment to solve the above problems. SUMMARY

[0006] The purpose of the present application is to provide a frozen preparation labeling equipment, which can complete the labeling operation of the product without the process of thawing and refreezing the frozen preparation product, ensure that the quality and activity of the product are not damaged, and has a low cost.

[0007] To achieve this purpose, the present application adopts the following technical solutions:

[0008] Provided is a frozen preparation labeling device, comprising an operation box body, the operation box body comprising a storage box body and a labeling box body, the labeling box body being arranged on the upper layer of the storage box body, and a labeling operation table being arranged between the labeling box body and the storage box body;

[0009] At least one exposure opening is arranged on the labeling operation table, at least one mounting cavity is arranged in the storage box body, a temporary storage cold box is arranged in the mounting cavity, the temporary storage cold box is open at the top, the top opening of the temporary storage cold box is opposite to the exposure opening, and a first refrigeration structure is arranged in the temporary storage cold box;

[0010] At least one inlet and outlet is arranged on the side wall of the labeling box body, the inlet and outlet allow the frozen preparation product to pass through, and the hands of a labeling personnel pass in and out of the labeling box body through the operation opening.

[0011] As a preferred scheme of the frozen preparation labeling device provided by the application, a second refrigeration structure is arranged on at least one inner wall of the labeling box body.

[0012] As a preferred scheme of the frozen preparation labeling device provided by the application, the labeling box body is open at the top, and a sealable cover plate is arranged at the top opening of the labeling box body.

[0013] A carrier disc is arranged in the labeling box body, and the second refrigeration structure is arranged between the carrier disc and the sealable cover plate.

[0014] As a preferred scheme of the frozen preparation labeling device provided by the application, the frozen preparation labeling device further comprises a gas joint and a coil pipe connected in communication.

[0015] The gas joint is arranged on the side wall of the labeling box body, and the gas joint is configured to be connected with an air inlet of a temperature and humidity control device; the coil pipe is arranged on the carrier disc, and an air outlet of the coil pipe is arranged to be in communication with the inside of the labeling box body.

[0016] The temperature and humidity control device is used to pass dry gas into the labeling box body through the gas joint and the coil pipe.

[0017] As a preferred scheme of the frozen preparation labeling device provided by the application, a pull opening is arranged on the side wall of the storage box body, the temporary storage cold box can be pulled out of the mounting cavity through the pull opening, a track is arranged in the mounting cavity along the pulling direction of the temporary storage cold box, and the temporary storage cold box is slidably connected with the track.

[0018] A first handle structure is arranged on the temporary storage cold box.

[0019] As a preferred scheme of the freeze-preparation labeling equipment provided by the application, the inlet and outlet are provided with openable and closable door bodies, which can open or seal cover the inlet and outlet.

[0020] The door bodies are provided with sealing strips.

[0021] The door bodies are provided with second handle mechanisms.

[0022] As a preferred scheme of the freeze-preparation labeling equipment provided by the application, the operation ports are provided with operation gloves.

[0023] As a preferred scheme of the freeze-preparation labeling equipment provided by the application, the labeling box body is provided with the inlet and outlet on opposite sides along a first direction; the labeling box body is provided with two operation ports on opposite sides along a second direction; the labeling operation table top is provided with four exposure ports arranged in a 2x2 array, so that the labeling operation table top is in a cross shape; the storage box body is provided with one mounting cavity provided with the temporary storage cold box corresponding to each exposure port; the operation ports and the temporary storage cold boxes are one-to-one corresponding.

[0024] The first direction is perpendicular to the second direction.

[0025] As a preferred scheme of the freeze-preparation labeling equipment provided by the application, a side wall of the labeling box body provided with the operation ports is made of transparent material; or, a side wall of the labeling box body provided with the operation ports is provided with a visual window.

[0026] And / or, the labeling operation table top is a smooth plane or is provided with grooves or protrusions for positioning the freeze-preparation products.

[0027] As a preferred scheme of the freeze-preparation labeling equipment provided by the application, the freeze-preparation labeling equipment further comprises a bottom support frame, the operation box body is arranged on the bottom support frame, and walking wheels are arranged on the bottom of the bottom support frame.

[0028] The freeze-preparation labeling equipment provided by the application has the following beneficial effects:

[0029] The application provides a frozen preparation labeling equipment, a temporary storage cold box is used for temporarily storing frozen preparation products to be labeled, a first refrigeration structure arranged in the temporary storage cold box can keep the temporary storage cold box at low temperature, so that the frozen preparation is kept in a suitable storage temperature environment, during labeling, the frozen preparation products are transferred into the temporary storage cold box through an inlet and outlet of a labeling box body, the hands of an operator are inserted into the labeling box body through an operation port, the frozen preparation products are labeled one by one on a labeling operation table, and after labeling and checking, the frozen preparation products are transferred into an ultra-low temperature refrigerator through the inlet and outlet, the whole labeling process does not need to thaw and freeze the frozen preparation products again, the products are kept in a low temperature environment, the quality and activity of the products are not damaged, the label of the frozen products does not slip and fall off, the use information of the products is clear and definite, and use errors are avoided. In addition, the labeling equipment has small volume, simple manufacturing and low cost. BRIEF DESCRIPTION OF DRAWINGS

[0030] Figure 1 is a first view of the frozen preparation labeling equipment provided by the embodiment of the application;

[0031] Figure 2 is a second view of the frozen preparation labeling equipment provided by the embodiment of the application.

[0032] In the figure:

[0033] 1, operation box body; 2, bottom support frame; 3, walking wheel; 4, gas joint; 5, coil pipe;

[0034] 11, storage box body; 12, labeling box body; 13, labeling operation table;

[0035] 111, temporary storage cold box; 1111, first handle structure;

[0036] 121, inlet and outlet; 122, operation port; 123, sealing cover plate; 124, carrier disc; 125, door body; 126, baffle;

[0037] 1231, pull handle; 1251, second handle structure;

[0038] 131, exposure port. DETAILED DESCRIPTION

[0039] The application will be further described in detail below in combination with the drawings and embodiments. It can be understood that the specific embodiments described herein are only used to explain the application, and not to limit the application. In addition, it should be noted that, in order to facilitate description, only the parts related to the application are shown in the drawings, not all structures.

[0040] In the description of the present application, unless otherwise explicitly specified and limited, the terms "connected", "connected", "fixed" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0041] In the present application, unless otherwise explicitly specified and limited, the "upper" or "lower" of the first feature to the second feature can include that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, the "upper", "above" and "on" of the first feature to the second feature includes that the first feature is directly above and obliquely above the second feature, or only indicates that the horizontal height of the first feature is higher than that of the second feature. The "below", "under" and "under" of the first feature to the second feature includes that the first feature is directly below and obliquely below the second feature, or only indicates that the horizontal height of the first feature is less than that of the second feature.

[0042] In the description of the present embodiment, the terms "upper", "lower", "left", "right" and other orientation or position relationship are based on the orientation or position relationship shown in the drawings, and are only for the convenience of description and simplification of operation, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0043] As shown in Figure 1 and Figure 2 The present embodiment provides a frozen preparation labeling equipment, which comprises an operation box body 1, the operation box body 1 comprises a storage box body 11 and a labeling box body 12, the labeling box body 12 is arranged on the upper layer of the storage box body 11, and a labeling operation table top 13 is arranged between the labeling box body 12 and the storage box body 11. At least one exposure port 131 is arranged on the labeling operation table top 13, at least one mounting cavity is arranged in the storage box body 11, a temporary storage cold box 111 is arranged in the mounting cavity, the top of the temporary storage cold box 111 is open, the top of the temporary storage cold box 111 is opposite to the exposure port 131, and a first refrigeration structure is arranged in the temporary storage cold box 111. At least one inlet and outlet 121 and at least one operation port 122 are arranged on the side wall of the labeling box body 12, the inlet and outlet 121 allow the frozen preparation product to pass through, and the hands of the labeling personnel pass in and out of the labeling box body 12 through the operation port 122.

[0044] The temporary storage cold box 111 is used for temporarily storing the frozen preparation products to be labeled. The first refrigeration structure arranged in the temporary storage cold box 111 can keep the temporary storage cold box 111 at a low temperature, so that the frozen preparation products are kept in a suitable storage temperature environment. During the labeling operation, the frozen preparation products are transferred into the temporary storage cold box 111 through the inlet and outlet 121 of the labeling box body 12. The hands of the operator are inserted into the labeling box body 12 through the operation opening 122, and the frozen preparation products are labeled one by one on the labeling operation table 13. After the labeling is completed and no error is found, the frozen preparation products are transferred into the ultra-low temperature refrigerator through the inlet and outlet 121. The whole labeling process does not need to thaw and freeze the frozen preparation products again. The products are always kept in a low temperature environment, so that the quality and activity of the products are not damaged. After the products are frozen, the label will not slip and fall off, so that the use of the product information is complete and clear, and the use error is avoided. In addition, the labeling equipment has small size, simple manufacturing and low cost.

[0045] The label arranged on the frozen preparation product is an ultra-low temperature waterproof label. The label can be made of paper, film or other special materials, and the back is coated with an adhesive.

[0046] Optionally, the first refrigeration structure is dry ice, a refrigerant or other refrigeration objects (such as a small refrigerator). In the embodiment, dry ice is placed in the temporary storage cold box 111 to keep the temporary storage cold box 111 at a low temperature. Moreover, since the temporary storage cold box 111 has an opening at the top, the cold air in the temporary storage cold box 111 can be transferred into the labeling box body 12, so that the whole labeling box body 12 is also kept in a low temperature environment.

[0047] In the embodiment, optionally, referring to Figure 1 and Figure 2 , the labeling box body 12 is provided with the inlet and outlet 121 on the opposite sides along the first direction. The labeling box body 12 is provided with two operation openings 122 on the opposite sides along the second direction. The first direction is perpendicular to the second direction. Specifically, the operation box body 1 has a rectangular structure. One of the first direction and the second direction is the length direction of the operation box body 1, and the other is the width direction of the operation box body 1. The products can enter and exit the labeling box body 12 along the first direction, and the hands of the operator are inserted into the labeling box body 12 along the second direction. The layout of the labeling equipment is compact, so that the labeling operation is more orderly and reasonable.

[0048] The labeling operation table 13 is provided with four exposure openings 131 arranged in a 2x2 array, so that the labeling operation table 13 has a cross shape. The storage box body 11 is provided with one mounting cavity in which the temporary storage cold box 111 is mounted, corresponding to each exposure opening 131. That is, a total of four temporary storage cold boxes 111 are arranged. The four temporary storage cold boxes 111 correspond to the four operation openings 122 one by one. When the hands of the operator enter the labeling box body 12 through the operation opening 122, it is convenient and handy to take out the frozen preparation products from the temporary storage cold box 111.

[0049] In the remaining embodiments, the number and distribution of the inlet and outlet 121, the operation port 122, the display port 131, and the mounting cavity for mounting the temporary storage cold box 111 can be set according to design requirements, and the setting position of the inlet and outlet 121 and the operation port 122 can also be set according to design requirements, and is not limited to the number, distribution, and setting position in the above-mentioned embodiments. For example, the entire labeling device is in a long strip shape, and three or four or more operation ports 122, display ports 131, etc. are arranged thereon, as long as the scheme includes the inlet and outlet 121, the operation port 122, the display port 131, and the mounting cavity for mounting the temporary storage cold box 111, regardless of the number, distribution, and setting position, which is within the protection scope of the present application.

[0050] Optionally, the side wall of the labeling box 12 provided with the operation port 122 is made of transparent material. In the present embodiment, the two opposite side walls of the labeling box 12 along the second direction are made of transparent material, realizing the visualization of the labeling operation. Exemplarily, the two side walls are made of transparent tempered glass material, facilitating the setting of the operation port 122, and not easy to be scratched, ensuring the clarity and facilitating the operator to observe the label through the tempered glass. Of course, the two side walls can also be made of transparent plastic material.

[0051] Alternatively, in some embodiments, a visual window can also be arranged on the side wall of the labeling box 12 provided with the operation port 122, through which the operator can observe the internal labeling. That is, not the entire side wall provided with the operation port 122 is made of transparent material, but part of the area is set as a visual area. The above-mentioned visual window can be a visual through hole opened on the labeling box 12, and no baffle can be arranged in the visual through hole, or a baffle made of transparent material can be mounted in the visual through hole, through which the inside of the labeling box 12 can be observed. The baffle made of transparent material can be made of glass or plastic material.

[0052] Optionally, the operation port 122 is in the shape of an oval hole, a waist-shaped hole, or a circular hole, etc.

[0053] In an optional embodiment, an operation glove is mounted at the operation port 122. The operator wears the operation glove to label the frozen preparation product, which on the one hand ensures that the frozen preparation product will not be contaminated, and on the other hand protects the operator's hands from frostbite.

[0054] In a new embodiment, the operation glove can also not be mounted at the operation port 122, and the operator can wear the operation glove outside and then enter the labeling box 12 through the operation port 122.

[0055] In the present embodiment, the operation glove is a Hypalon glove.

[0056] Optionally, the labeling operation table 13 is a smooth plane; or, the labeling operation table 13 is provided with grooves or protrusions for positioning the frozen preparation products, preventing the frozen preparation products from moving at will, especially when the frozen preparation products are accidentally bumped, the positioning of the grooves or protrusions can limit the position of the frozen preparation products, so as not to cause the frozen preparation products to be knocked down.

[0057] Referring to Figure 1 and Figure 2 , the frozen preparation labeling equipment further comprises a bottom support frame 2, the operation box body 1 is arranged on the bottom support frame 2, and walking wheels 3 are installed at the bottom of the bottom support frame 2. The arrangement of the support frame supports the bottom of the operation box body 1, so that the operation port 122 is at a height suitable for the hands of the operator to enter. The arrangement of the walking wheels 3 enables the entire labeling equipment to be transported to a designated location.

[0058] The walking wheels 3 are preferably universal wheels, each of which is provided with a brake mechanism to prevent the labeling equipment from moving accidentally.

[0059] Of course, in other embodiments, the operation box body 1 can also be fixedly arranged on a table, which can be designed as required.

[0060] At least one inner wall position of the labeling box body 12 is provided with a second refrigeration structure for auxiliary cooling of the inside of the labeling box body 12. In this embodiment, the top wall position of the labeling box body 12 is provided with the second refrigeration structure.

[0061] Specifically, referring to Figure 2 , the top of the labeling box body 12 is open, and a sealable cover plate 123 is arranged at the top opening of the labeling box body 12; a carrier disc 124 is arranged in the labeling box body 12, and the second refrigeration structure is arranged between the carrier disc 124 and the sealable cover plate 123. When the sealable cover plate 123 is arranged at the top opening of the labeling box body 12, the sealable cover plate 123, the carrier disc 124 and the side wall of the labeling box body 12 form a sealed chamber, and the second refrigeration structure is arranged in the chamber for auxiliary cooling of the inside of the labeling box body 12, so that the labeling environment is in a low-temperature state.

[0062] Referring to Figure 1 , a pull handle 1231 is arranged on the sealable cover plate 123, and the sealable cover plate 123 can be conveniently opened or buckled at the top opening of the labeling box body 12 through the pull handle 1231. The sealable cover plate 123 can be made of PP material.

[0063] Optionally, the second refrigeration structure is dry ice, a refrigerant or other refrigeration objects (such as a small refrigeration device). In this embodiment, dry ice is placed on the carrier disc 124. Since the dry ice is placed on the top carrier disc 124 of the labeling box body 12 and in the temporary storage cold box 111 below, the inside of the entire labeling box body 12 can be effectively ensured to be in a low-temperature environment.

[0064] Referring to Figure 2 , the freeze preparation labeling equipment further comprises a component connected with the temperature and humidity control device, which comprises a gas joint 4 and a coil pipe 5. The temperature and humidity control device is provided with a gas outlet through which dry gas can be output, and the gas joint 4 is arranged on the side wall of the labeling box body 12 and connected with the gas outlet of the temperature and humidity control device. The coil pipe 5 is arranged on the loading disc 124. The temperature and humidity control device is connected with the air inlet of the coil pipe 5 through the gas joint 4, and the air outlet of the coil pipe 5 is connected with the inside of the labeling box body 12. The temperature and humidity control device can output dry gas into the inside of the labeling box body 12 through the gas joint 4 and the coil pipe 5, which can realize drying and dehumidification in the inside of the labeling box body 12 on the one hand, so as to avoid that too much humidity in the labeling box body 12 affects the labeling quality; on the other hand, the dry ice on the loading disc 124 is stacked above the coil pipe 5 and used for cooling the coil pipe 5, so that the temperature of the dry gas flowing in the coil pipe 5 is reduced, and the dry and cold gas after cooling is output into the inside of the labeling box body 12 through the air outlet of the coil pipe 5, thereby further realizing cooling in the inside of the labeling box body 12 and effectively controlling the labeling environment temperature.

[0065] Further, the temperature in the inside of the labeling box body 12 can be adjusted by adjusting the speed of the dry gas output by the temperature and humidity control device, for example, if the temperature needs to be further reduced, the gas flow can be increased, so that more dry and cold gas is output into the inside of the labeling box body 12 through the air outlet of the coil pipe 5. In addition, the temperature in the inside of the labeling box body 12 can also be controlled by the amount of dry ice stacked in the temporary storage cold box 111 and on the loading disc 124.

[0066] Further, the operation of outputting dry gas makes the inside of the labeling box body 12 have a positive pressure relative to the outside, which can prevent external air from entering the inside of the labeling box body 12.

[0067] Referring to Figure 1 and Figure 2 , the side wall of the storage box body 11 is provided with a pulling opening, and the temporary storage cold box 111 can be pulled out of the installation chamber through the pulling opening, so as to place dry ice or refrigerant in the temporary storage cold box 111. The installation chamber is provided with a rail along the pulling direction of the temporary storage cold box 111, and the temporary storage cold box 111 and the rail are slidably matched, which can guide and limit the pulling movement of the temporary storage cold box 111 and make the pulling operation more convenient and labor-saving.

[0068] The temporary storage cold box 111 is provided with a first handle structure 1111, which is convenient for an operator to pull out or push back the temporary storage cold box 111 into the installation chamber through the first handle structure 1111.

[0069] Referring to Figure 1 and Figure 2The import and export 121 is provided with a door 125 which can be opened and closed. The door 125 can be opened or sealed to cover the import and export 121. When the frozen preparation product is transferred between the temporary storage cold box 111 and the outside of the device, the door 125 is in an open state. After the transfer is completed, the door 125 is closed to maintain the low temperature in the labeling box 12.

[0070] In this embodiment, two rotatable doors 125 are arranged at each import and export 121. A sealing strip is arranged on the door 125 to reduce the overflow of cold air in the labeling box 12. The sealing strip can be a rubber sealing strip. A second handle structure 1251 is arranged on the door 125 to facilitate the opening and closing of the door 125 by the operator.

[0071] A baffle 126 is arranged at the upper part of the import and export 121. When the door 125 is closed, it abuts against the baffle 126.

[0072] The labeling device can control the temperature in the labeling box 12 to be between -10℃ and 25℃, while maintaining the humidity below 20%. A low-temperature and low-humidity environment is realized. The storage temperature of the product in the temporary storage cold box 111 can be as low as -80℃. The operator enters the inside of the labeling box 12 through the operation gloves to perform the labeling operation.

[0073] Based on the above-mentioned frozen preparation labeling device, the present embodiment further provides a frozen preparation labeling method, which specifically comprises the following steps:

[0074] S1, the packaged frozen preparation product is frozen in a refrigerator according to the storage conditions.

[0075] S2, the frozen frozen preparation product is transferred to a room for labeling.

[0076] S3, in the labeling device, dry compressed air is introduced into the inside of the labeling box 12 through the gas joint 4 and the coil 5, and dry ice is placed on the carrier disc 124 to ensure the low temperature and low humidity in the labeling box 12.

[0077] S4, the first refrigeration structure (dry ice) is placed in the four temporary storage cold boxes 111 of the storage box 11 of the labeling device, and the frozen preparation product to be labeled is transferred for temporary storage.

[0078] S4, the operator wears the operation gloves and enters the inside of the labeling box 12 through the operation port 122, and completes the labeling bottle by bottle, and observes through the transparent side wall of the labeling box 12.

[0079] S5, after the labeling inspection, the frozen preparation product is timely transferred to the ultra-low temperature refrigerator for storage.

[0080] Obviously, the above embodiments of the present application are merely exemplary but not intended to limit the embodiments of the present application. Various obvious changes, re-adjustments and substitutions can be made by those skilled in the art without departing from the scope of the present application. It is not necessary or possible to enumerate all the embodiments. Any modification, equivalent replacement and improvement made within the spirit and principle of the present application shall be included in the protection scope of the claims of the present application.

Claims

1. A freeze formulation labelling apparatus characterised in that, The application relates to a cold medicine labeler, which comprises an operation box (1) including a storage box (11) and a label box (12) arranged on the upper layer of the storage box (11), and a label operation table (13) arranged between the label box (12) and the storage box (11). At least one exposure port (131) is arranged on the label operation table (13), at least one mounting cavity is arranged in the storage box (11), a temporary storage cold box (111) is arranged in the mounting cavity, the top of the temporary storage cold box (111) is open, the top of the temporary storage cold box (111) is opposite to the exposure port (131), and a first refrigeration structure is arranged in the temporary storage cold box (111). At least one inlet and outlet (121) and at least one operation port (122) are arranged on the side wall of the label box (12), the inlet and outlet (121) are used for allowing frozen medicine products to pass through, and the operation port (122) is used for allowing the hands of labelers to enter and exit the label box (12). A second refrigeration structure is arranged at the position of at least one inner wall of the label box (12). The top of the label box (12) is open, and a sealable sealing cover plate (123) is arranged at the top of the label box (12). A carrier disc (124) is arranged in the label box (12), and the second refrigeration structure is arranged between the carrier disc (124) and the sealing cover plate (123). The cold medicine labeler further comprises a gas joint (4) and a coil pipe (5) connected in communication. The gas joint (4) is arranged on the side wall of the label box (12), and is configured to be connected with an air inlet of a temperature and humidity control device; the coil pipe (5) is arranged on the carrier disc (124), and an air outlet of the coil pipe (5) is arranged in the label box (12). The temperature and humidity control device is used for introducing dry gas into the label box (12) through the gas joint (4) and the coil pipe (5).

2. The freeze -formulation labeling apparatus according to claim 1, characterized by A pull-out opening is arranged on the side wall of the storage box (11), the temporary storage cold box (111) can be pulled out of the mounting cavity through the pull-out opening, a track is arranged in the mounting cavity along the pulling direction of the temporary storage cold box (111), and the temporary storage cold box (111) is slidably matched with the track. A first handle structure (1111) is arranged on the temporary storage cold box (111).

3. The freeze -form labeler of claim 1, wherein, A door body (125) is arranged at the inlet and outlet (121), and the door body (125) can open or seal the inlet and outlet (121). A sealing strip is arranged on the door body (125). A second handle structure (1251) is arranged on the door body (125).

4. The freeze formulation labelling apparatus according to any one of claims 1 to 3, wherein An operation glove is arranged at the operation port (122).

5. The freeze formulation labelling apparatus according to any one of claims 1 to 3, wherein The label sticking box (12) is provided with the inlet and outlet (121) on both sides opposite along the first direction; the label sticking box (12) is provided with two operation openings (122) on both sides opposite along the second direction; the label sticking operation table top (13) is provided with four exposure openings (131) in 2x2 array distribution, so that the label sticking operation table top (13) is in cross type, and the storage box (11) is provided with one mounting cavity for mounting the temporary storage cold box (111) corresponding to each exposure opening (131); the operation opening (122) and the temporary storage cold box (111) are one-to-one corresponding; The first direction is perpendicular to the second direction.

6. The freeze formulation labelling apparatus according to any one of claims 1 to 3, wherein The side wall of the label sticking box (12) provided with the operation opening (122) is made of transparent material; or, the side wall of the label sticking box (12) provided with the operation opening (122) is provided with a visual window. And / or, the label sticking operation table top (13) is a smooth plane or is provided with a groove or a protrusion for positioning the frozen preparation product.

7. The freeze formulation labeling apparatus according to any one of claims 1 to 3, characterized by, The frozen preparation labeling equipment further comprises a bottom support frame (2), and the operation box (1) is arranged on the bottom support frame (2), and walking wheels (3) are mounted on the bottom of the bottom support frame (2).

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