A miticide and its application

Abstract

The present invention belongs to the technical field of pesticidal acaricides, and discloses an acaricide and its application. The acaricide comprises active ingredient A and active ingredient B. The active ingredient A is a compound of formula I: The active ingredient B is any one of etoxazole, lufenuron or flufenerim. The mass ratio of the active ingredient A to the active ingredient B is 1:50 to 45:1. The acaricide of the present invention has excellent control effects on common harmful mites on crops and garden plants, can effectively reduce the usage amount of pesticides, and reduce the harm to the environment.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticide acaricide and discloses an acaricide and application thereof. Background Art

[0002] Ethoxazole, CAS No.: 153233-91-1, chemical name: 4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole, is an oxazole acaricide, a diphenyloxazoline derivative, which mainly inhibits the normal molting process of mites and has ovicidal activity, so it can effectively control the entire juvenile stage of mites and also cause female adult mites to be infertile. Its main control targets are red spider mites in apples and citrus, and it also has excellent control effects on mites such as spider mites, early spider mites, panonychus mites, two-spotted spider mites, and cinnabar spider mites in crops such as cotton, flowers, and vegetables.

[0003] Lufenuron, CAS number: 103055-07-8, chemical name: N-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluorobenzamide, is a chitin synthesis inhibitor. Its mechanism of action is to inhibit the enzyme that catalyzes chitin polymerization in harmful mites / insects, thereby interfering with the normal growth and development of insects.

[0004] Fluopyrim, CAS No.: 918162-02-4, chemical name: (2E)-2-(2-{[2-chloro-4-(trifluoromethyl)phenoxy]methyl}phenyl)-3-methoxyacrylate, is a methoxyacrylate-based highly effective fungicide and miticide. It can be used to control diseases caused by ascomycetes, basidiomycetes and conjugated fungi, such as wheat rust, powdery mildew, cucumber powdery mildew, anthracnose, black spot, corn leaf blight, rice sheath blight, etc. It also has high activity against mites such as spider mites on apples and citrus, such as red spider mites.

[0005] Mites are a type of herbivorous arthropods belonging to the phylum Arthropoda, class Arachnida, order Acari. They have a small number of individuals, a wide range of activities, rapid reproduction in high temperature and drought, a short generation cycle, and strong drug resistance. Agricultural pest mites are one of the most difficult biological groups to control in the world. There are more than 40 species of agricultural pest mites in my country, which have a strong destructive ability to economic crops such as fruit trees, vegetables, and flowers, seriously affecting the normal physiological functions of crop leaves and even reducing production. At present, the prevention and control of pest mites mainly adopts chemical prevention and control methods, and acaricides are the main means of modern agricultural prevention and control of pest mites. In agricultural production, the effectiveness of pest mites against various acaricides has decreased year by year. After research, the applicant found that compounding sulfiflumin with etoxazole, lufenuron or fluazifop-butyl in a suitable mass ratio has a significant synergistic effect on pest mites, effectively improving the control effect of field pest mites, and is safe for plants, reducing the amount of pesticides used, and reducing environmental pollution. Summary of the Invention

[0006] Based on the above, the object of the present invention is to provide an acaricide, which has a significant synergistic effect on harmful mites on agricultural and garden plants, can effectively reduce the usage amount of pesticides, and reduce the harm to the environment.

[0007] To achieve the above object, the present invention adopts the following technical solution: an acaricide, which contains active ingredient A and active ingredient B, and the active ingredient A is a compound of formula I: (Formula I), and the active ingredient B is any one of etoxazole, lufenuron or flufenzin;

[0008] Further, the mass ratio of active ingredient A to active ingredient B in the acaricide is 1:50 to 45:1.

[0009] Further, the mass ratio of active ingredient A to active ingredient B in the acaricide is 1:45 to 35:1;

[0010] Further, the active ingredient B is etoxazole, and the mass ratio of active ingredient A to active ingredient B is 1:45 to 35:1;

[0011] The active ingredient B is lufenuron, and the mass ratio of active ingredient A to active ingredient B is 1:35 to 35:1;

[0012] The active ingredient B is flufenzin, and the mass ratio of active ingredient A to active ingredient B is 1:30 to 15:1;

[0013] Further, based on the total weight of the acaricide being 100%, the total weight of active ingredient A and active ingredient B accounts for 0.1% to 80% of the total weight of the acaricidal composition;

[0014] Further, in addition to the active ingredients, the acaricide also contains auxiliary ingredients permitted in pesticides, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreezing agents, defoaming agents, solvents, preservatives, stabilizers, synergists, binders, fillers or carriers.

[0015] Further, the acaricide can be prepared into a pesticide-acceptable formulation dosage form, and the formulation dosage form is a solid formulation or a liquid formulation.

[0016] Further, the solid preparation is a granule, a strip, a wettable powder, an oil-dispersible powder, an emulsion powder, a water-dispersible granule, an emulsion granule, a water-dispersible tablet, a soluble powder, a soluble tablet or a soluble granule, and the liquid preparation is a soluble solution, a soluble sol, an oil, a film-forming oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an emulsion in water, an oil-in-water emulsion, a microemulsion, a fat, a suspending agent, a microcapsule suspending agent, an oil suspending agent, a dispersible oil suspending agent or a suspo-emulsion;

[0017] Further, the solid preparation is a wettable powder or a water-dispersible granule, and the liquid preparation is an emulsifiable concentrate, a water suspension or a water-dispersible granule;

[0018] The present invention also discloses the application of the acaricide as described above in controlling acarid pests of crops and garden plants.

[0019] Further, the plant acarid pests are Tetranychus cinnabarinus, Tetranychus urticae or Panonychus citri.

[0020] The present invention has the following advantages:

[0021] The acaricide of the present invention has a significant synergistic effect on common acarid pests on agricultural and garden plants. Especially, it has a good control effect on Tetranychus cinnabarinus, Tetranychus urticae and Panonychus citri. It can slow down the development of acarid pest resistance, reduce the usage amount of pesticides, is safe to plants and friendly to the environment. Specific Embodiments

[0022] In order to make the technical solutions of the present invention clearer, the technical solutions of the present invention are explained and illustrated by combining specific preparation examples and implementation examples.

[0023] Preparation Examples of Preparations:

[0024] Preparation Example 1: 27% sulfiflumin·etoxazole suspending agent (1:8)

[0025] Formulation composition: 3% sulfiflumin, 24% etoxazole, 1% fatty alcohol polyoxyethylene ether, 5% styrylphenol polyoxyethylene ether phosphate, 1% sodium lignosulfonate, 0.25% xanthan gum, 5% ethylene glycol, 0.1% sodium benzoate, 0.5% silicone oil, and deionized water is added to make up the balance;

[0026] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional auxiliaries are successively placed in a reaction kettle, mixed evenly with water, subjected to high-speed shearing and wet grinding, and finally homogenized and filtered to obtain the suspending agent product.

[0027] Preparation Example 2: 42% sulfiflumin·etoxazole water-dispersible granule (5:1)

[0028] Formulation composition: 35% sulfiflumin, 7% etoxazole, 8% sodium lignosulfonate, 2% Nekal BX, 8% sodium polycarboxylate, 4% ammonium sulfate, kaolin to make up the balance;

[0029] Preparation method: According to the formulation ratio of the examples, add the active ingredients to the carrier, and add surfactants and other functional auxiliaries thereto, mix, add 10 - 25% of water after air-flow comminution, and then obtain the water dispersible granule product through kneading, granulation, drying, and screening; or spray water, granulate, and dry the comminuted powder in a fluidized bed granulator, and then screen to obtain the product.

[0030] Preparation Example 3: 16% sulfiflumin·etoxazole EC (1:3)

[0031] Formulation composition: 4% sulfiflumin, 12% etoxazole, 15% EO / PO block copolymer, 12% acetophenone, 10% propylene glycol methyl ether, 1% calcium dodecylbenzenesulfonate, xylene to make up the balance;

[0032] Preparation method: According to the formulation ratio of the examples, add the metered active ingredients, solvents, and cosolvents to a blending kettle, stir to dissolve them, then add the emulsifier, make up the balance with the remaining solvent, stir evenly in a stirring kettle, and filter to obtain the EC required by the present invention.

[0033] Preparation Example 4: 12% sulfiflumin·lufenuron EC (1:2)

[0034] Formulation composition: 4% sulfiflumin, 8% lufenuron, 15% N-methylpyrrolidone, 14% styrylphenol polyoxyethylene ether, 2% calcium dodecylbenzenesulfonate, 10% DMF, methyl oleate to make up the balance;

[0035] Preparation method: The same as Preparation Example 3.

[0036] Preparation Example 5: 21% sulfiflumin·lufenuron SC (6:1)

[0037] Formulation composition: 18% sulfiflumin, 3% lufenuron, 2% polyoxyethylene ether of Guerbet alcohol, 3% polyoxypropylene ether of alkylaryl polyoxyethylene ether, 2% phosphoric acid ester of triphenylethylene phenol ethoxylate, 1% sodium polycarboxylate, 1.5% magnesium aluminum silicate, 0.2% carboxyethyl cellulose, 1% sodium sorbate, 5% ethylene glycol, 0.5% silicone oil, deionized water to make up the balance;

[0038] Preparation method: The same as Preparation Example 1.

[0039] Preparation Example 6: 30% sulfiflumin·lufenuron water dispersible granule (3:2)

[0040] Formulation composition: 18% sulfiflumin, 12% lufenuron, 10% dispersant NNO, 2% sodium dodecyl sulfate, 6% sodium lignosulfonate, 30% starch, light calcium carbonate to make up the balance;

[0041] Preparation method: The same as Preparation Example 2.

[0042] Preparation Example 7: 27% sulfiflumin·fludioxonil suspension concentrate (4:5)

[0043] Formulation composition: 12% sulfiflumin, 15% fludioxonil, 2% isomeric tridecyl alcohol polyoxyethylene ether, 4% triphenylethylene phenol ethoxylate phosphate ester, 1% lignosulfonate, 3% alkylaryl polyoxyethylene ether polyoxypropylene ether, 0.25% xanthan gum, 5% glycerol, 0.1% sodium benzoate, 0.5% silicone oil, deionized water to make up the balance;

[0044] Preparation method: The same as Preparation Example 1.

[0045] Preparation Example 8: 39% sulfiflumin·fludioxonil water dispersible granules (1:12)

[0046] Formulation composition: 3% sulfiflumin, 36% fludioxonil, 8% sodium lignosulfonate, 2% Nekal BX, 8% naphthalene sulfonate formaldehyde condensate D425, 5% white sugar, kaolin to make up the balance;

[0047] Preparation method: The same as Preparation Example 2.

[0048] Preparation Example 9: 16% sulfiflumin·fludioxonil emulsifiable concentrate (7:1)

[0049] Formulation composition: 14% sulfiflumin, 2% fludioxonil, 15% EO / PO block copolymer, 15% acetophenone, 10% N-octylpyrrolidone, 1% calcium dodecylbenzenesulfonate, mesitylene to make up the balance;

[0050] Preparation method: The same as Preparation Example 3.

[0051] The above-prepared preparation examples have all passed the tests and meet the quality and technical indicators required for the corresponding preparations, and the prepared products are qualified preparations recognized in the art.

[0052] Example 1: Indoor bioactivity determination test

[0053] Test basis: The test refers to NY / T 1154.12-2008 "Pesticide indoor bioassay test guidelines Insecticides Part 12: Slide dipping method for spider mites".

[0054] Test targets: Tetranychus urticae Koch and Tetranychus cinnabarinus. Select nymphs with consistent physiological states.

[0055] Test agents: sulfiflumin technical, etoxazole technical, lufenuron technical, and flufenerim technical, provided by the group's R & D center.

[0056] Test preparation: Cut double-sided tape into 2-cm lengths and stick one end to a glass slide. Select healthy mites and stick their backs to the double-sided tape (do not stick the legs, antennae, and mouthparts). Place 30 mites on each slide and put them into a container lined with a wet sponge. Cover the container and place it at 25 ± 1°C. After 2 hours, examine under a microscope and remove dead and injured individuals, then make up to 30 mites per slide.

[0057] Agent preparation: Dissolve the test agents in a suitable solvent and prepare 5 series of mass concentration gradients for each single agent and each mixture ratio according to the mixing purpose and agent activity design.

[0058] Agent treatment: Immerse the glass slide in the liquid medicine and gently shake for 5 s, then take it out, blot the excess liquid medicine with filter paper, place it in a white porcelain dish lined with a wet sponge, and cover it with a plastic film with good light transmittance. Each treatment has 4 replicates, and a treatment without the agent (including all organic solvents and emulsifiers) is set as the blank control.

[0059] Rearing and observation: Place the container with the test insects at a temperature of (25 ± 1)°C and a photoperiod of L:D = (16:8) h for rearing and observation.

[0060] Test investigation: Examine under a microscope 48 h after treatment to check the mortality of the test insects, and record the total number of insects and the number of dead insects separately.

[0061] Calculate the mortality of each treatment based on the investigation data. Calculate according to the following formula:

[0062]

[0063] In the formula:

[0064] P —— Mortality, in percentage (%);

[0065] K —— Represents the number of dead insects, in number;

[0066] N —— Represents the total number of insects in the treatment, in number.

[0067]

[0068] In the formula:

[0069] P1 —— Corrected mortality, in percentage (%).

[0070] P t —— Mortality rate for treatment, in percentage (%);

[0071] P0 —— Mortality rate of blank control, in percentage (%).

[0072] If the control mortality rate < 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to formula (2); if the control mortality rate > 20%, the test needs to be redone.

[0073] Analyze using DPS statistical analysis system to obtain LC 50 value and evaluate the activity of the test agent on the biological test material.

[0074] The co-toxicity coefficient (CTC value) of the mixture is calculated according to formulas (3), (4), and (5):

[0075]

[0076] Where:

[0077] ATI —— Measured toxicity index of the mixture;

[0078] S —— LC 50 of the standard acaricide, in milligrams per liter (mg / L);

[0079] M —— LC 50 of the mixture, in milligrams per liter (mg / L).

[0080] TTI = TI A ×P A +TI B ×P B

[0081] Where:

[0082] TTI —— Theoretical toxicity index of the mixture;

[0083] TI A —— Toxicity index of agent A;

[0084] P A —— Percentage content of agent A in the mixture, in percentage (%);

[0085] TI B —— Toxicity index of agent B;

[0086] P B —— Percentage content of agent B in the mixture, in percentage (%).

[0087]

[0088] In the formula:

[0089] CTC——coefficient of co-toxicity;

[0090] ATI——actual toxicity index of mixture;

[0091] TTI——theoretical toxicity index of mixture.

[0092] When the co-toxicity coefficient CTC of the mixture is ≥120, it shows a synergistic effect; when CTC ≤80, it shows an antagonistic effect; when 80 < CTC < 120, it shows an additive effect.

[0093] The results of the indoor toxicity test are shown in the following table:

[0094] Table 1 Test results of the indoor biological activity of the mixture of sulfiflumin and etoxazole against Tetranychus urticae

[0095] Test agents Toxicity regression equation <![CDATA[LC 50 (mg / L)]]> Coefficient of co-toxicity Sulfiflumin(A) y = 5.4740 + 1.5962x 0.5047 / Etoxazole(B) y = 3.9338 + 1.5138x 5.0615 / A:B = 1:50 y = 4.0496 + 1.5161x 4.2352 101.535 A:B = 1:45 y = 4.2414 + 1.4151x 3.4358 123.146 A:B = 1:35 y = 4.2959 + 1.6452x 2.6789 151.055 A:B = 1:25 y = 4.4364 + 1.5463x 2.3144 162.327 A:B = 1:10 y = 4.6920 + 1.4960x 1.6065 173.037 A:B = 1:5 y = 4.9408 + 1.2350x 1.1167 180.955 A:B = 5:1 y = 5.8459 + 1.8599x 0.3509 169.221 A:B = 10:1 y = 5.8399 + 1.8213x 0.3458 158.961 A:B = 25:1 y = 5.6494 + 1.5785x 0.3878 134.812 A:B = 35:1 y = 5.5827 + 1.5207x 0.4138 125.096 A:B = 45:1 y = 5.5198 + 1.5875x 0.4705 109.410

[0096] It can be seen from the results of the indoor biological test that when sulfiflumin and etoxazole are mixed in a suitable mass ratio, it has excellent control effect against Tetranychus urticae. Among them, the mass ratio of sulfiflumin to etoxazole is 1:45 to 35:1, and the co-toxicity coefficient is greater than 120, showing a synergistic effect.

[0097] Table 2 Test results of the indoor biological activity of the mixture of sulfiflumin and lufenuron against Tetranychus urticae

[0098] Test agents Toxicity regression equation <![CDATA[LC 50 (mg / L)]]> Coefficient of co-toxicity Sulfiflumin(A) y = 5.4740 + 1.5962x 0.5047 / Lufenuron(B) y = 3.3392 + 1.7294x 9.1260 / A:B = 35:1 y = 5.4957 + 1.5443x 0.4775 108.545 A:B = 20:1 y = 5.6072 + 1.5952x 0.4163 126.945 A:B = 10:1 y = 5.5960 + 1.5305x 0.4079 135.355 A:B = 8:1 y = 5.6251 + 1.5131x 0.3863 145.971 A:B = 4:1 y = 5.6633 + 1.5631x 0.3764 165.321 A:B = 1:1 y = 5.3833 + 1.5310x 0.5619 170.221 A:B = 1:4 y = 4.9305 + 1.7221x 1.0974 188.278 A:B = 1:8 y = 4.5956 + 1.6120x 1.7818 176.703 A:B = 1:10 y = 4.4992 + 1.3319x 2.3769 150.363 A:B = 1:20 y = 4.2427 + 1.3627x 3.5951 139.937 A:B = 1:35 y = 3.9607 + 1.4880x 4.9941 123.882

[0099] It can be seen from the results of the indoor determination test that when sulfiflumin and lufenuron are mixed, when their mass ratio is 20:1 to 1:35, the co-toxicity coefficient against Tetranychus urticae is greater than 120, showing a synergistic effect.

[0100] Table 3 Test results of the indoor biological activity of the mixture of sulfiflumin and flufenzin against Tetranychus urticae

[0101] Test agents Toxicity regression equation <![CDATA[LC 50 (mg / L)]]> Coefficient of co-toxicity Sulfiflumin(A) y = 5.4740 + 1.5962x 0.5047 / Flufenerim(B) y = 3.8921 + 1.7595x 4.2626 / A:B = 1:45 y = 4.2510 + 1.4573x 3.2658 112.339 A:B = 1:25 y = 4.3735 + 1.5011x 2.6142 126.756 A:B = 1:15 y = 4.5345 + 1.5005x 2.0428 142.398 A:B = 1:7 y = 4.7835 + 1.4748x 1.4022 157.450 A:B = 1:3 y = 5.0596 + 1.5926x 0.9174 162.379 A:B = 1:1 y = 5.3465 + 1.4701x 0.5811 155.315 A:B = 3:1 y = 5.5544 + 1.6337x 0.4578 141.412 A:B = 7:1 y = 5.5391 + 1.4118x 0.4151 136.643 A:B = 15:1 y = 5.4453 + 1.1766x 0.4183 127.691 A:B = 25:1 y = 5.3968 + 1.2876x 0.4918 106.225 A:B = 45:1 y = 5.2517 + 0.9649x 0.5484 93.830

[0102] It can be seen from the results of the indoor biological test that when sulfiflumin and flufenzin are mixed, when the mass ratio is 1:25 to 15:1, it shows a synergistic effect against Tetranychus urticae.

[0103] Table 4 Test results of the indoor biological activity of the mixture of sulfiflumin and etoxazole against Tetranychus cinnabarinus

[0104] Test agents Toxicity regression equation <![CDATA[LC 50 (mg / L)]]> Coefficient of co-toxicity Sulfiflumin(A) y = 5.1145 + 1.3081x 0.8175 / Etoxazole(B) y = 3.7663 + 1.4953x 6.6842 / A:B = 1:50 y = 4.0485 + 1.4018x 4.7727 122.775 A:B = 1:45 y = 4.2043 + 1.3369x 3.9372 146.859 A:B = 1:35 y = 4.2168 + 1.3826x 3.6854 151.224 A:B = 1:25 y = 4.3367 + 1.3116x 3.2045 163.468 A:B = 1:8 y = 4.6126 + 1.3888x 1.9008 195.647 A:B = 1:5 y = 4.6697 + 1.4312x 1.7014 178.895 A:B = 5:1 y = 5.3287 + 1.4421x 0.5916 161.862 A:B = 8:1 y = 5.2649 + 1.1412x 0.5860 154.580 A:B = 25:1 y = 5.1907 + 1.1607x 0.6851 123.495 A:B = 35:1 y = 5.1921 + 1.3239x 0.7160 117.029 A:B = 45:1 y = 5.0652 + 1.0736x 0.8695 95.848

[0105] From the results of indoor biological tests, it can be seen that when sulfiflumin is compounded with etoxazole, at a mass ratio of 1:45 to 25:1, it shows a synergistic effect on Tetranychus cinnabarinus.

[0106] Table 5 Test results of indoor biological activity of the mixture of sulfiflumin and lufenuron against Tetranychus cinnabarinus

[0107]

[0108]

[0109] From the results of indoor biological tests, it can be seen that when sulfiflumin is compounded with lufenuron, at a mass ratio of 1:10 to 35:1, it shows a synergistic effect on Tetranychus cinnabarinus.

[0110] Table 6 Test results of indoor biological activity of the mixture of sulfiflumin and flufenzin against Tetranychus cinnabarinus

[0111] Test agents Toxicity regression equation <![CDATA[LC 50 (mg / L)]]> Coefficient of co-toxicity sulfiflumin(A) y = 5.1145 + 1.3081x 0.8175 / Flufenerim(B) y = 3.5223 + 1.7130x 7.2884 / A:B = 1:40 y = 3.8874 + 1.5416x 5.2694 115.933 A:B = 1:30 y = 4.0599 + 1.5073x 4.2047 138.082 A:B = 1:15 y = 4.3127 + 1.3569x 3.2101 151.899 A:B = 1:7 y = 4.6180 + 1.4351x 1.8456 198.502 A:B = 1:3 y = 4.7781 + 1.4987x 1.4062 173.994 A:B = 1:1 y = 5.0109 + 1.4576x 0.9829 149.568 A:B = 3:1 y = 5.1906 + 1.4383x 0.7370 142.567 A:B = 7:1 y = 5.2521 + 1.4608x 0.6721 136.818 A:B = 15:1 y = 5.2297 + 1.5358x 0.7087 122.129 A:B = 30:1 y = 5.1192 + 1.5014x 0.8330 101.033 A:B = 40:1 y = 5.0074 + 1.2794x 0.9867 84.686

[0112] From the results of indoor biological tests, it can be seen that when sulfiflumin is compounded with flufenzin, at a mass ratio of 1:30 to 15:1, it shows a synergistic effect on Tetranychus cinnabarinus.

[0113] Example 2: Field efficacy test of acaricidal composition against Tetranychus urticae

[0114] Test site: This test was carried out in Shaojiazhuang Village, Mancheng District, Baoding City, Hebei Province. The soil fertility of the test site is relatively high, and the cultivation and management conditions are good. The water and fertilizer management of all test plots is uniform and consistent, meeting the local scientific agricultural practices.

[0115] Test target: Tetranychus urticae on strawberries.

[0116] Test crop: Strawberries.

[0117] Test design: A total of 8 treatments were set up in the test, with clear water as the blank control. Each treatment was replicated 4 times, and the area of each plot was 30m 2 , and a randomized block arrangement was adopted, with two rows of strawberries spaced between each plot.

[0118] Test method: When applying the medicine, a 3WBD-20 knapsack electric sprayer was used to evenly spray the liquid medicine on both the front and back sides of the strawberry leaves. The medicine application time was March 22, 2023, and a total of 1 application was made.

[0119] Investigation method: Before applying the pesticide, the initial mite population was investigated. The population density of mites was investigated on the 3rd day and 10th day after applying the pesticide. When investigating, a hand-held magnifying glass was used to observe and record the number of live mites on both the front and back sides of the leaves. Five-point sampling was carried out in each plot. One plant was fixed at each point, and five mite-infested leaves were fixed on each plant to investigate the number of mites.

[0120] Method for calculating the efficacy:

[0121]

[0122]

[0123] Results and analysis:

[0124] Table 7 Results of the field efficacy test of the acaricidal composition against Tetranychus urticae

[0125]

[0126] It can be seen from the field efficacy test in Table 7 that the control effects of 27% sulfiflumin·etoxazole suspension concentrate (1:8), 21% sulfiflumin·lufenuron suspension concentrate (6:1), and 16% sulfiflumin·fludioxonil EC (7:1) against Tetranychus urticae were 85.53%, 81.00%, and 80.15% on the 3rd day after application, and 93.27%, 92.52%, and 89.44% on the 14th day after application, respectively.

[0127] Example 3: Field efficacy test of the acaricidal composition against Tetranychus cinnabarinus

[0128] Test site: The test was carried out in a vegetable greenhouse in Shouguang City, Weifang City, Shandong Province. The soil layer of the test site was deep, and the soil fertility was medium to high. All test plots conformed to local conventional agricultural practices.

[0129] Test target: Tetranychus cinnabarinus.

[0130] Test crop: Eggplant.

[0131] Test design: The area of each plot in the test field was 20 m 2 , and all test plots were arranged in a randomized block design with 4 replicates for each treatment. The pesticide was applied at the initial stage of the occurrence of Tetranychus cinnabarinus. When applying the pesticide, each pesticide treatment was diluted to a certain concentration, and a Gongnong-16 type sprayer was used to spray the whole eggplant plant to ensure that both the front and back sides of each leaf were evenly covered with the pesticide.

[0132] Investigation method: Five eggplant plants were fixed in each plot, and three leaves were investigated on each eggplant plant. Before applying the pesticide, the initial population of Tetranychus cinnabarinus was investigated. The number of surviving mites was investigated on the 3rd day, 7th day, and 15th day after applying the pesticide, and the reduction rate of mite population and the control effect were calculated.

[0133] Method for calculating the efficacy:

[0134]

[0135]

[0136] Field efficacy test results and analysis:

[0137] Table 8 Field efficacy test results of acaricidal composition against Tetranychus cinnabarinus

[0138]

[0139] From the field efficacy test results, it can be seen that the combination of sulfiflumin with etoxazole, lufenuron or flufenzin has good control effects against Tetranychus cinnabarinus. The 42% sulfiflumin·etoxazole water dispersible granules (5:1), 30% sulfiflumin·lufenuron water dispersible granules (3:2), and 27% sulfiflumin·flufenzin suspension concentrate (4:5) showed good quick-acting properties against Tetranychus cinnabarinus 3 days after application. 15 days after application, the control effects of the 42% sulfiflumin·etoxazole water dispersible granules (5:1), 30% sulfiflumin·lufenuron water dispersible granules (3:2), and 27% sulfiflumin·flufenzin suspension concentrate (4:5) against Tetranychus cinnabarinus were 93.59%, 95.64%, and 92.85% respectively, with a long lasting efficacy period.

[0140] Example 4: Field efficacy test of acaricidal composition against Panonychus citri

[0141] Test site: Citrus orchard in Qingcao Village, Qingjiang Town, Zixing City, Hunan Province. The water and fertilizer conditions and cultivation management in this area are relatively consistent. The test crop is Dongjiang tangerine with normal growth.

[0142] Test design: In this test, 7 pesticide treatments and 1 clear water control were set. The pesticide treatments were respectively: 16% sulfiflumin·etoxazole emulsifiable concentrate (1:3), 16% sulfiflumin·flufenzin emulsifiable concentrate (7:1), 12% sulfiflumin·lufenuron emulsifiable concentrate (1:2), 20% etoxazole suspension concentrate, 22% lufenuron emulsifiable concentrate, 21% flufenzin suspension concentrate, 20% sulfiflumin water dispersible granules.

[0143] Test plot setting: Each treatment had 3 trees, repeated 4 times, and arranged randomly. A protection row was set around the test plot. During the test process, no pesticides or clear water were applied to the protection row, and conventional management was carried out.

[0144] Pesticide application time: May 13, 2023. The weather was cloudy and there was a gentle breeze during pesticide application. Uniform foliar spraying was used. When spraying, the front and back sides of the leaves were evenly wetted with the liquid medicine until it just began to drip.

[0145] Investigation method: The mite population density before treatment was investigated, and the number of live mites was investigated 3 days, 8 days, and 14 days after treatment. In each plot, young shoots were marked at five positions, namely east, south, west, north, and middle, on each tree. The number of active mites on 25 leaves of each tree was investigated. The leaf surface was directly observed with a hand-held magnifying glass to count the number of mites.

[0146] Method for calculating the efficacy:

[0147]

[0148]

[0149] Results and analysis of the field efficacy test:

[0150] Table 9 Results of the field efficacy test of the acaricidal composition against Panonychus citri

[0151]

[0152] As can be seen from the test results in Table 9, the acaricidal composition of the present invention has a good control effect against Panonychus citri, and both the quick-acting property and the long-lasting period are significantly better than those of the single-agent control.

[0153] Although the present invention has been described in detail with general descriptions and specific embodiments above, based on the present invention, some modifications or improvements can be made, which are obvious to those skilled in the art. Therefore, these modifications or improvements made without departing from the spirit of the present invention all fall within the scope of the present invention claimed.

Claims

1. A miticide, characterized in that, The acaricide described above contains active ingredient A and active ingredient B. The active ingredient A is a compound of formula I: (Formula I), the active ingredient B is etoxazole, and the mass ratio of the active ingredient A to the active ingredient B is 1:45 to 35:

1.

2. The acaricide according to claim 1, characterized in that, The mass ratio of the active ingredient A to the active ingredient B is 1:45 to 25:

1.

3. The acaricide according to claim 1, characterized in that, Based on the total weight of the acaricide being 100 wt%, the total weight of the active ingredient A and the active ingredient B accounts for 0.1 wt% to 80 wt% of the total weight of the acaricide.

4. The acaricide according to claim 1, characterized in that, In addition to the active ingredients, the acaricide further contains auxiliary ingredients permitted in pesticides, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreezing agents, defoaming agents, solvents, preservatives, stabilizers, synergists, binders, fillers or carriers.

5. The acaricide according to claim 1, characterized in that, The acaricide can be prepared into a pesticide-acceptable formulation dosage form, and the formulation dosage form is a solid formulation or a liquid formulation.

6. The acaricide according to claim 5, characterized in that, The solid formulation is a wettable powder or a water-dispersible granule, and the liquid formulation is an emulsifiable concentrate, a water emulsion, a microemulsion, a suspension concentrate, a dispersible oil suspension.

7. Use of the acaricide according to any one of claims 1-6 for controlling mite pests of crops and garden plants, characterized in that, The plant mite pests are Tetranychus cinnabarinus and Tetranychus urticae.

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