Anti-flushing liquid sampling device and analyzer

Abstract

The present invention discloses an anti-liquid-swinging sampling device and an analyzer, the anti-liquid-swinging sampling device comprises a moving mechanism and a sampling needle, the moving mechanism is connected to the sampling needle and is used to drive the sampling needle to move, the sampling needle comprises a needle body, an outer tube and a fixing piece, the outer tube is sleeved on the outer wall of the needle body, the fixing piece is sleeved on the outer wall of the outer tube and is used to be connected with the moving mechanism; wherein, the outer tube extends toward the bottom relative to the fixing piece and is set as a first extension section, and the needle body extends toward the bottom relative to the fixing piece and is set as a second extension section; the length of the first extension section is less than or equal to 0.6 times the length of the second extension section. The present invention designs the length relationship of each part in the sampling needle on the basis of satisfying the structural rigidity and the effective use length of the sampling needle, and has the function of enhancing the anti-mechanical vibration performance of the sampling needle, thereby preventing the occurrence of liquid-swinging phenomenon.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an anti-flushing liquid sampling device and an analyzer. Background Art

[0002] The sampling needle is a commonly used component in in vitro diagnostic analyzers, which is used to absorb and / or discharge samples, reagents, cleaning fluids and other liquids. After the sampling needle completes the absorption / discharge of liquids, it needs to move to the specified position through the transfer structure (translation, rotation) to complete the next action. Common transfer structures include rocker arms, such as the structures involved in patent documents CN207908534, CN202378061U, etc.

[0003] In the process of absorbing liquid, it is inevitable that some liquid will remain on the outer surface of the sampling needle, which will cause a high probability of liquid splashing during the subsequent translation and rotation of the sampling needle, also known as liquid throwing. Especially in high-speed analyzers, the sampling needle transfer rate is relatively high, which will further aggravate the degree of liquid throwing, greatly affecting the cleanliness of the test environment. If the liquid splashes into the reagent or sample, it may also cause contamination, resulting in deviations in the test results. Summary of the invention

[0004] The purpose of the present invention is to provide an anti-liquid-throwing sampling device and an analyzer, aiming to solve the problem that the existing sampling needle is prone to liquid throwing during the movement of absorbing / discharging liquid agents, causing pollution to the environment, reagents and samples.

[0005] In order to solve the above technical problems, the object of the present invention is achieved through the following technical solutions: Provide an anti-flushing liquid sampling device, comprising a moving mechanism and a sampling needle, wherein the moving mechanism is connected to the sampling needle and is used to drive the sampling needle to move, characterized in that the sampling needle comprises a needle body, an outer tube and a fixing member, wherein the outer tube is sleeved on the outer wall of the needle body, and the fixing member is sleeved on the outer wall of the outer tube and is used to be connected to the moving mechanism;

[0006] The outer tube extends outwardly by a first extension segment relative to the fixing member, and the needle body extends outwardly by a second extension segment relative to the fixing member; the length of the first extension segment is less than or equal to 0.6 times the length of the second extension segment.

[0007] Furthermore, the moving mechanism includes a rocker arm that can rotate and move linearly; one end of the rocker arm is the rotation center, and the sampling needle is arranged at the other end of the rocker arm; the unit mass of the rocker arm is arranged in a way that the distance from the sampling needle decreases rather than increases.

[0008] Further, the bending section moment of the rocker arm is arranged in such a way that it does not increase with increasing distance from the rotation center.

[0009] Furthermore, the relationship between the length of the rocker arm and the bending section moment along the length direction is:

[0010] f(x)=a1x+b1, x∈[0, L1);

[0011] f(x)=a2x+b2, x∈[L1, L2);

[0012] f(x)=a3x+b3, x∈[L2, L3];

[0013] Among them, f(x) is the bending section moment at the corresponding position; a1, a2, a3, b1, b2, b3 are all coefficients; x, L1, L2 and L3 all represent the distance from the rotation center on the rocker arm.

[0014] Furthermore, the smaller the unit mass of the longitudinal section of the rocker arm along the length direction, the smaller the bending section moment at the corresponding longitudinal section.

[0015] Furthermore, the relationship between the unit mass of the longitudinal section of the rocker arm along the length direction and the bending section moment at the corresponding position is: f(x)=a*e bx , where a and b are coefficients, x represents the unit mass of the longitudinal section, and f(x) is the bending section moment at the corresponding longitudinal section.

[0016] Furthermore, the moving mechanism also includes a floating connection assembly; the floating connection assembly is connected to one end of the rocker arm and is used to drive the rocker arm to rotate and move linearly; the floating connection assembly is arranged to float in the vertical direction with the rocker arm to absorb the stress generated by the rocker arm during the vertical movement.

[0017] Furthermore, the dynamic mechanism includes: a base, a center spline, an adapter plate, a driving member and a guide member; the center spline passes through the top of the base and can move up and down in the base, one end of the center spline passes through the base and is connected to one end of the rocker arm, and one end of the center spline is located in the internal cavity of the base and is fixedly connected to the adapter plate; the driving member and the guide member are both arranged in the internal cavity of the base, the driving member is fixedly connected to the adapter plate and is used to drive the center spline to move up and down in the base; the guide member is floatingly connected to the adapter plate in the vertical direction.

[0018] Furthermore, the guide member includes a connecting plate, a connecting port is provided in the adapter plate, the connecting plate is extended in the horizontal direction and inserted in the connecting port, and a movable gap is left between the connecting plate and the inside of the connecting port in the vertical direction.

[0019] Furthermore, the sampling needle has a variable diameter structure; and / or the sampling needle is surface treated; and / or an insulating layer is provided on the outside of the sampling needle body.

[0020] An embodiment of the present invention provides another analyzer, comprising the anti-fluid-swinging device as described above.

[0021] Compared with the prior art, the anti-flushing liquid sampling device provided by the embodiment of the present invention has at least the following beneficial effects:

[0022] On the one hand, the length relationship of each part of the sampling needle is designed, which effectively enhances the anti-mechanical vibration performance of the sampling needle on the basis of satisfying the structural rigidity and the effective use length of the sampling needle. On the other hand, the unit mass distribution design, bending section moment design, mass balance design and reinforcement rib design are carried out along the length direction of the entire rocker arm; and the sampling needle and the rocker arm are designed to be connected in a floating manner; based on this, when the rocker arm drives the sampling needle to move, the mechanical vibration of the rocker arm can be weakened, so that the tension of the liquid hanging on the sampling needle is sufficient to counteract the mechanical vibration and inertia. Based on the improvements in these two aspects, the phenomenon of liquid throwing is effectively prevented.

[0023] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention and implement it according to the contents of the specification, the following is a detailed description of the preferred embodiments of the present invention in conjunction with the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying any creative work.

[0025] Figure 1 A schematic diagram of the overall structure of the anti-flushing liquid sampling device provided in an embodiment of the present invention;

[0026] Figure 2 Another overall structural schematic diagram of the anti-flushing liquid sampling device provided in an embodiment of the present invention;

[0027] Figure 3 Another overall structural schematic diagram of the anti-flushing liquid sampling device provided in an embodiment of the present invention;

[0028] Figure 4 A schematic diagram of the internal structure of a base of an anti-flushing liquid sampling device provided in an embodiment of the present invention;

[0029] Figure 5 A schematic diagram of the structure of a sampling needle of an anti-flushing liquid sampling device provided in an embodiment of the present invention;

[0030] Figure 6 A schematic diagram of the distance-bending section moment of the anti-flushing liquid sampling device provided in an embodiment of the present invention;

[0031] Figure 7 A schematic diagram of unit mass-bending section moment of the anti-flushing liquid sampling device provided in an embodiment of the present invention.

[0032] Description of the symbols in the figure:

[0033] 1. Rocker arm; 11. First part; 12. Second part; 13. Reinforcement rib;

[0034] 2. Floating connection assembly; 21. Base; 22. Center spline; 23. First adapter plate; 24. Second adapter plate; 25. Slide rail; 26. Guide member; 261. Connecting plate; 27. Motor; 28. Transmission belt;

[0035] 3. Sampling needle; 31. Needle body; 32. Outer tube; 33. Fixing piece; 34. Sampling end. DETAILED DESCRIPTION

[0036] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] It should be understood that when used in this specification and the appended claims, the terms "include" and "comprises" indicate the presence of described features, integers, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components and / or combinations thereof.

[0038] It should also be understood that the terms used in this specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. As used in the specification of the present invention and the appended claims, unless the context clearly indicates otherwise, the singular forms "a", "an" and "the" are intended to include plural forms.

[0039] It should be further understood that the term "and / or" used in the present description and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.

[0040] See also Figure 1The embodiment of the present invention provides an anti-flushing sampling device, including a moving mechanism and a sampling needle 3. After the sampling needle 3 comes into contact with the liquid, such as but not limited to aspirating liquid, aspirating samples, aspirating buffer, aspirating diluent, washing, etc., the sampling needle 3 is driven to complete the transfer through the rotational motion and / or linear motion of the moving mechanism. During this process, part of the liquid (called hanging liquid in the field) is likely to remain on the outer wall of the sampling needle, so it is easy to cause liquid throwing during the transfer process. In order to solve this problem, the present invention improves the moving mechanism and the sampling needle 3 respectively.

[0041] The following is a detailed introduction to the improvements to the mobile mechanism:

[0042] Embodiment 1:

[0043] In one embodiment, the moving mechanism includes a rocker arm 1 that can rotate and move linearly; the rocker arm 1 rotates with one end as the rotation center P, and the sampling needle 3 is arranged at the other end of the rocker arm 1. The present application finds that reasonable unit mass distribution of the moving mechanism can reduce the mechanical vibration of the moving mechanism and reduce the inertia at the location of the sampling needle 3.

[0044] In this embodiment, the rotation center P of the rocker arm 1 is taken as the zero point (0 point), and the unit mass of the entire rocker arm 1 is distributed along the length direction. Specifically, the unit mass of the rocker arm is set in a manner that the distance from the sampling needle decreases rather than increases.

[0045] In this embodiment, a feasible distribution method is: the unit mass distribution of the position closer to the sampling needle 3 on the rocker arm 1 is smaller, and conversely, the unit mass distribution of the part farther away from the sampling needle 3 on the rocker arm 1 is larger. In this way, in the process of the rocker arm 1 driving the sampling needle 3 to move, the mechanical vibration of the rocker arm 1 can be reduced, and the inertia at the position where the sampling needle is located can also be reduced to ensure that the molecular tension of the liquid hanging on the sampling needle 3 is sufficient to counteract the influence of mechanical vibration, thereby preventing the occurrence of liquid throwing. It should be understood that in this embodiment, the unit mass of the rocker arm 1 can be distributed in a linear decreasing manner along the length direction, or in a nonlinear proportional decreasing manner.

[0046] Another feasible distribution method may be: within a certain part or certain parts of the length of the rocker arm, the unit mass does not change with the change of the distance, that is, it remains stable. This design is matched based on the force distribution during the operation of the rocker arm. For example, in areas where the force is relatively consistent, allocating the same unit mass is conducive to maintaining the stability of the rocker arm movement; for example, between two points where the force change is more obvious, by allocating the same unit mass and coordinating the change in distance (distance will affect inertia), a gradual change in force can be achieved, which also helps to maintain the stability of the rocker arm movement. Both methods can reduce the vibration of the rocker arm during movement. However, it should be understood that, from an overall perspective, the unit mass distribution from the center of rotation to the sampling needle in this embodiment is on a downward trend.

[0047] Embodiment 2:

[0048] In another embodiment based on the above embodiment, the present application finds that: the bending section moment (also known as the bending section coefficient) of the rocker arm is set in a manner that increases without increasing with the distance from the rotation center, which can also reduce the mechanical vibration of the rocker arm 1, thereby alleviating the liquid throwing phenomenon.

[0049] In this embodiment, a feasible implementation is to set the bending section moment of the rocker arm 1 to be smaller as the position is farther from the rotation center P. The present invention designs the corresponding relationship between the length of the rocker arm and the bending section moment through a large number of modeling, calculations and experiments, which can significantly improve the anti-fluid rejection performance. For example, Figure 1 As shown, taking the horizontal direction of the upper surface of the rocker arm 1 as the detection reference, four special points A, B, C, and D (i.e., the critical positions of the sudden change of the longitudinal section of the rocker arm, but not limited to the four points) are selected to divide the rocker arm into three sections of different lengths. The present invention sets the relationship between the length of the rocker arm and the bending section moment along the length direction as follows:

[0050] f(x)=a1x+b1, x∈[0, L1);

[0051] f(x)=a2x+b2, x∈[L1, L2);

[0052] f(x)=a3x+b3, x∈[L2, L3];

[0053] Among them, f(x) is the bending section moment at the corresponding position; a1, a2, a3, b1, b2, b3 are all coefficients; x, L1, L2 and L3 all represent the distance from the rotation center P on the rocker arm 1.

[0054] Specifically, with point A as 0, the above relationship is set as follows:

[0055] f(x)=-366.67x+13000, x∈[0, 30);

[0056] f(x)=-10x+2300, x∈[30, 130);

[0057] f(x)=-20x+3600, x∈[130, 160];

[0058] From this, the corresponding bending section moments at each distance are shown in Table 1 below (see also Figure 6 ):

[0059] Table 1

[0060] Location Distance from 0 point L / mm <![CDATA[Flexural section modulus / mm 3 > A 0 13000 B 30 2000 C 130 1000 D 160 400

[0061] It has been verified that the rocker arm arranged based on the relationship described in this embodiment has greatly improved anti-fluid throwing performance, and the critical speed and mechanical vibration causing fluid throwing are greatly improved.

[0062] Another feasible implementation in this embodiment is that within a certain portion or certain lengths of the rocker arm, the bending section moment does not change with the change of the distance, that is, it remains stable (such as a constant function). This method is also determined according to the distribution of the force. For example, for a sudden sudden change in force, an exponential function relationship can be considered, and for a smoothly changing force, a linear relationship can be considered, and so on.

[0063] In summary of various possible implementations of this embodiment, it should be understood that the above segmentation is not limited to being set to three sections, but can also be set to several sections according to the number of sudden changes in the cross-sectional area of ​​the rocker arm 1 along the length direction, and a specific function expression can be set for each section.

[0064] It should be understood that the number of segments and the physical parameters of the segments will also affect the expression of the relationship. For example, the piecewise function relationship is not limited to a linear relationship, but can also be a constant function, an exponential relationship, a polynomial relationship, a logarithmic relationship, etc.

[0065] It should be understood that the types of the piecewise function relationships may be the same or different.

[0066] Embodiment three:

[0067] Based on the aforementioned embodiment, in another embodiment, the present application finds that: under the premise of satisfying the aforementioned distribution relationship between distance, unit mass and bending section moment, the relationship between unit mass and bending section moment is reasonably designed to be a functional relationship, which can further improve the anti-flushing performance.

[0068] In this embodiment, the present invention has designed the relationship between the unit mass of the longitudinal section of the rocker arm 1 along the length direction and the bending section moment at the corresponding position through repeated modeling, calculation and testing. For example, it can be expressed in the form of an exponential function:

[0069] f(x)=a*ebx ,

[0070] Where a and b are coefficients, x represents the unit mass of the longitudinal section, and f(x) is the bending section moment at the corresponding longitudinal section;

[0071] More specifically, continue with Figure 1 Take point A as an example, and take point A as the zero point (0 point), the above exponential function relationship can be specifically set as:

[0072] f(x)=149*e 0.0129x ;

[0073] It can be obtained that the values ​​of unit mass and bending moment at some longitudinal sections are shown in Table 2 below (see also Figure 7 ):

[0074] Table 2

[0075] <![CDATA[Unit mass (g / mm 3) > 327 296 289 223 218 116 98 <![CDATA[Flexural section modulus (mm 3 )]]> 13000 8200 5800 1900 1700 1000 500

[0076] It should be understood that the relationship can also be set to linear, piecewise function, polynomial relationship, etc.

[0077] It has been verified that the rocker arm based on the relationship described in this embodiment has greatly improved anti-fluid throwing performance, and the critical speed and mechanical vibration amplitude at which fluid throwing occurs are increased.

[0078] Embodiment 4:

[0079] In one embodiment, the present applicant has found that performing mass balancing on both sides of the rocker arm 1 relative to the rotation center P can also reduce the mechanical vibration of the rocker arm 1, thereby alleviating the liquid throwing phenomenon.

[0080] In this embodiment, Figure 2 As shown, the present invention divides the entire rocker arm 1 into a first part 11 and a second part 12 with the rotation center P as the dividing line. The distances between the center of gravity of the first part 11 and the second part 12 and the rotation center P are L1 and L2 respectively, and the comprehensive masses of the two parts are m1 and m2 respectively. If the following relationship is satisfied, the entire rocker arm 1 reaches a completely balanced state: m1*L1=m2*L2. The so-called comprehensive mass refers to the mass at the center of gravity, that is, it is assumed that all weight is concentrated at the center of gravity.

[0081] Considering that a sampling needle 3 is added to the first part 11, it has a certain destructive effect on the inertial stability of the entire rocker arm 1. Therefore, the comprehensive mass of the mass balance part can be appropriately adjusted on the basis of having the sampling needle 3, that is, the above relationship can be set to: a*m1*L1=m2*L2, wherein a∈[0.1,1], the value of a is set according to the actual inertial stability influence of the sampling needle 3, and the value of a can be obtained by testing the inertial influence of the sampling needle 3 in a moving state, or can be set according to demand.

[0082] It should be understood that the relationship can also be set to linear, piecewise function, polynomial relationship, etc.

[0083] It has been verified that the rocker arm based on the relationship described in this embodiment has greatly improved anti-fluid throwing performance, and the critical speed and mechanical vibration amplitude at which fluid throwing occurs are increased.

[0084] Embodiment five:

[0085] In one embodiment, the present applicant has found that performing mass balancing on both sides of the rocker arm 1 relative to the rotation center P can also reduce the mechanical vibration of the rocker arm 1, thereby alleviating the liquid throwing phenomenon.

[0086] In this embodiment, Figure 2 As shown, the present invention divides the entire rocker arm 1 into a first part 11 and a second part 12 with the rotation center P as the dividing line. The distances between the center of gravity of the first part 11 and the second part 12 and the rotation center P are L1 and L2 respectively, and the comprehensive masses of the two parts are m1 and m2 respectively. If the following relationship is satisfied, the entire rocker arm 1 reaches a completely balanced state: m1*L1=m2*L2. The so-called comprehensive mass refers to the mass at the center of gravity, that is, it is assumed that all weight is concentrated at the center of gravity.

[0087] Considering that a sampling needle 3 is added to the first part 11, it has a certain destructive effect on the inertial stability of the entire rocker arm 1. Therefore, the comprehensive mass of the mass balance part can be appropriately adjusted on the basis of having the sampling needle 3, that is, the above relationship can be set to: a*m1*L1=m2*L2, wherein a∈[0.1,1], the value of a is set according to the actual inertial stability influence of the sampling needle 3, and the value of a can be obtained by testing the inertial influence of the sampling needle 3 in a moving state, or can be set according to demand.

[0088] Embodiment six:

[0089] In one embodiment, the present applicant has found that adding reinforcing ribs 13 to the rocker arm can improve the rigidity and strength of the rocker arm, thereby improving the stability of the rocker arm to reduce the phenomenon of liquid throwing.

[0090] In this embodiment, Figure 3As shown, the present invention sets a reinforcing rib 13 on the end of the rocker arm 1 near the rotation center P. The reinforcing rib 13 and the rocker arm body can be made of the same material or different materials; the manufacturing method can be one-piece molding, or assembly methods such as buckle connection, screw connection, and clamp connection. The present invention designs the reinforcing rib 13, on the one hand, to improve the rigidity and strength of the end of the rocker arm, and on the other hand, it can also play a role in continuing the mass distribution, further improving the stability of the rocker arm to reduce the phenomenon of liquid throwing.

[0091] It should be particularly noted that when the reinforcing ribs 13 are provided, the distribution of the unit mass and the bending section moment in the aforementioned embodiment should also take into account the contribution and influence of the reinforcing ribs 13 .

[0092] Embodiment seven:

[0093] Regarding the connection between the sampling needle 3 and the rocker arm 1, the present application found that the prior art generally uses a center spline 22 and a guide member 26 to achieve the connection between the sampling needle 3 and its drive assembly, such as Figure 4 As shown, the center spline 22 and the guide member 26 are usually fixedly connected (rigidly connected). In this case, due to the manufacturing and installation accuracy of the parts, there will be a certain deviation in the parallelism between the center spline 22 and the guide member 26. Therefore, there is a certain gap between the actual running route of the sampling needle 3 and the theoretical route, that is, its movement route is not completely parallel to the sliding route of the guide member 26. During the movement, this deviation will be converted into vibration when the sampling needle moves vertically, increasing the probability of liquid throwing, especially when the vibration frequency coincides with the frequency of the sampling needle 3, the vibration amplitude will be greatly increased. In addition, this fixed connection requires the driver to provide sufficient output power to overcome the vibration or deformation caused by the parallelism error, and the performance requirements of the driver are also high.

[0094] Therefore, this embodiment improves the connection mode between the center spline 22 and the guide member 26 in the prior art from a fixed connection (rigid connection) to a floating connection, so that the center spline 22 can move slightly to adapt to the parallelism error when driving the sampling needle 3 to move. The specific design is as follows:

[0095] like Figure 4 As shown, in one embodiment, the moving mechanism also includes a floating connection assembly 2 for absorbing the stress generated by the rocker arm during the vertical movement. The stress generally comes from the deviation between the theoretical movement path and the actual movement path of the sampling needle 3 caused by processing errors and assembly errors.

[0096] Specifically, the moving mechanism includes a base 21, a central spline 22, a driving member, a guiding member 26, and an adapter plate. The driving member and the guiding member 26 are both disposed inside the inner cavity of the base 21. The central spline 22 penetrates through the top of the base 21 and can move up and down within the base 21. One end of the central spline 22 that extends out is connected to one end of the rocker arm. One end of the central spline 22 located inside the inner cavity of the base 21 is fixedly connected to the adapter plate. The guiding member 26 is slidably disposed along the axial direction of the central spline 22, and the guiding member 26 is floatingly connected to the adapter plate in the vertical direction.

[0097] Further, the driving member includes a motor 27 and a transmission belt 28. The adapter plate is fixedly connected to the transmission belt 28. Thus, the reciprocating movement of the transmission belt 28 between the driving pulley and the driven pulley can be converted into the movement of the sampling needle 3 in the vertical direction through the adapter plate.

[0098] Further, the floating connection assembly 2 further includes a slide rail 25 disposed inside the base 21. The guiding member 26 is slidably assembled on the slide rail 25, thereby restricting the vertical movement path of the sampling needle 3 and improving the operation stability.

[0099] Further, the guiding member 26 includes a connecting plate 261 extending horizontally. The adapter plate includes a first adapter plate 23 and a second adapter plate 24 disposed at intervals, and the first adapter plate 23 and the second adapter plate 24 are rigidly connected in a "C" shape. During assembly, the connecting plate 261 is horizontally inserted into the "C" - shaped space (i.e., the connection port of the adapter plate) between the first adapter plate 23 and the second adapter plate 24. There are certain gaps between the upper and lower surfaces of the connecting plate 261 and the first adapter plate 23 and the second adapter plate 24 respectively. The gaps can not only achieve transmission but also ensure the freedom degree between the connecting plate 261 and the adapter plate, allowing slight movement between the two to adapt to the parallelism deviation.

[0100] In some other embodiments, on the basis of the above - mentioned Embodiment Six, rolling bearings can be used to connect the first adapter plate 23 and the second adapter plate 24 respectively. The balls of the rolling bearings are in contact with the first adapter plate 23 and the second adapter plate 24 respectively. Thus, slight movement is also allowed between the connecting plate 261 and the whole adapter plate.

[0101] In some other embodiments, on the basis of the above - mentioned Embodiment Six, chutes can be provided on both the first adapter plate 23 and the second adapter plate 24. Sliding parts are slidably assembled on the chutes. The upper and lower surfaces of the connecting plate 261 are respectively connected to the corresponding sliding parts. Thus, slight movement is also allowed between the connecting plate 261 and the whole adapter plate.

[0102] In some other embodiments, on the basis of the above-mentioned Embodiment VI, the end of the connecting plate 261 can also be set as a spring or a flexible material, and the spring or the flexible material is fixedly connected to the side wall of the "C"-shaped structure of the adapter plate. In this way, elastic deformation can also be utilized to allow a small movement between the connecting plate 261 and the adapter plate.

[0103] In some other embodiments, on the basis of the above-mentioned Embodiment VI, the first adapter plate 23 and the second adapter plate 24 are rigidly connected through a columnar structure in the center, and a through hole is provided on the connecting plate 261 and sleeved outside the columnar structure through the through hole. The aperture of the through hole is slightly larger than the outer diameter of the columnar structure. In this way, a small movement can also be allowed between the connecting plate 261 and the whole adapter plate.

[0104] It should be understood that in this embodiment, through different structural designs, small movements can occur between the upper and lower surfaces of the connecting plate 261 and the first adapter plate 23 and the second adapter plate 24 respectively, that is, the radial offset during the movement of the sampling needle 3 can be absorbed, thereby effectively eliminating the vibration caused by the parallelism error.

[0105] It has been verified that by using the rocker arm of the floating connection assembly 2, the anti-liquid-throwing performance has been greatly improved, and both the critical speed of liquid throwing and the mechanical vibration have been greatly improved.

[0106] Next, the improvement of the sampling needle 3 will be specifically introduced:

[0107] Embodiment VIII:

[0108] In one embodiment, as Figure 5 shown, the sampling needle 3 includes a needle body 31, an outer tube 32 and a fixing member 33. The outer tube 32 is sleeved outside one end of the needle body 31 and connects this end to the fixing member 33. The outer tube 32 extends outward from the fixing member 33 by a first extension section L (L also represents the length of the outward extension), and the needle body 31 extends outward from the fixing member 33 by a second extension section M (M also represents the length of the outward extension).

[0109] This application discovers that the range of L / M has a direct impact on the anti-liquid-throwing performance of the sampling needle 3. On the one hand, under the condition that the diameters of the outer tube 32 and the needle body 31 remain unchanged, the larger L / M is, the stronger the rigidity of the needle body 31 itself is, and the stronger the anti-liquid-throwing characteristic of the needle body 31 itself is; however, the larger L / M is, it also means that the range of the length of the needle body 31 (i.e., the effective use length) that can participate in the "liquid suction - liquid discharge - cleaning" process is smaller, which greatly limits its scope of use.

[0110] In this embodiment, the length of the first extension section designed by the present invention should be less than or equal to 0.6 times the length of the second extension section (that is, L / M≤0.6), which can take into account both the anti-flushing performance and its effective use length; preferably, 0.2≤L / M≤0.55, more preferably, L / M=0.26, 0.4.

[0111] It has been demonstrated that, on the one hand, the corresponding relationship of L / M≤0.6 can meet the effective use length (ML) of the sampling needle 3, ensuring that the aspiration and / or discharge actions required by the analyzer can be completed using the effective use length; on the other hand, the outer tube 32 increases the rigidity near the root of the sampling needle 3, which can resist deformation that may be caused during movement, and effectively prevent the occurrence of liquid throwing.

[0112] Embodiment nine:

[0113] In one embodiment, the present application has found that surface treatment of the needle body 31 can improve the hydrophobicity of the needle body 31 and also improve the anti-flushing performance of the sampling needle.

[0114] In this embodiment, one surface treatment method is to coat a hydrophobic layer on the surface of the needle body 31, such as coating Teflon; another surface treatment method is to nano-treat the surface structure of the needle body 31, such as controlling the surface grains within the nano-size range through heat treatment or shot peening; another surface treatment is to spray a nano-layer on the surface of the needle body 31, and the sprayed material can be a compound material containing one or more of Au, Ag or Cr, or it can be a fluorocarbon, PTFE or polyethersulfone based material.

[0115] Embodiment ten:

[0116] In one embodiment, the present application has found that the use of a variable diameter structure can improve the anti-flushing performance of the sampling needle 3. Specifically, the sampling end 34 of the needle body 31 includes a connecting section, a transition section and a working section; the connecting section is connected to the needle body 31, the transition section is connected to the connecting section, and the working section is connected to the transition section; the cross-sectional areas of the connecting section, the transition section and the working section are arranged in descending order.

[0117] In this embodiment, the sampling end 34 of the needle body 31 extends outward from the main body, and the cross-sections of the needle body 31 at various locations have uniform dimensions, such as a cylindrical structure. The sampling end 34 includes an integrally formed connecting section, a transition section, and a working section, wherein the connecting section is connected to the needle body 31, or directly extends outward from the needle body 31, and the cross-sectional dimension parameters of the connecting section are consistent with those of the needle body 31. The transition section adopts a variable diameter structure, and the cross-sectional area of ​​the transition section gradually decreases from the connecting section to the working section. The cross-sectional areas of the working section have uniform dimensions, such as a cylindrical structure. Based on this, the liquid is more easily separated from the needle body 31, reducing the risk of hanging liquid, thereby also improving the anti-flushing performance of the sampling needle 3.

[0118] In some other embodiments, the needle body 31 , the outer tube 32 and the fixing member 33 may be assembled in one piece and connected to the rocker arm 1 via the fixing member 33 , so that the rocker arm 1 drives the entire sampling needle 3 to move.

[0119] In some other embodiments, the outer diameter of the needle body 31 may be 1.5-2.5 mm, preferably 2 mm.

[0120] In some other embodiments, the outer tube 32 of this embodiment can be made of metal materials, such as stainless steel tube, titanium alloy tube, etc.; the cross-sectional shape of the outer tube 32 matches the cross-sectional shape of the needle body 31; the outer diameter of the outer tube 32 can be 3.5-4.5mm, preferably 4mm, and the inner diameter can be 3-4mm, preferably 3.6mm.

[0121] In some other embodiments, the sampling needle 3 also includes an insulating tube, which is arranged between the outer tube 32 and the needle body 31. The insulating tube is preferably a heat shrink tube, and the length of the heat shrink tube matches the length of the outer tube 32 to ensure that the area on the needle body 31 corresponding to the outer tube 32 can be covered after heat shrinkage; the heat shrink tube is made of one or more materials such as PVC, PE, PVDF, PTFE, FED, fluororubber, EPDM, etc., and the shrinkage ratio of the heat shrink tube can be 2:1, 3:1, 4:1.

[0122] In this embodiment, the installation method of the outer tube 32, the needle body 31, and the heat shrink tube includes the following steps:

[0123] First, the material and length of the heat shrink tube are selected according to the shrinkage ratio, the outer diameter of the needle body 31 and other parameters, and the heat shrink tube is placed at an appropriate position outside the needle body 31;

[0124] Then, the heat shrink tube and the needle body 31 are placed in a set temperature environment to complete heat shrinkage, wherein the set temperature is 65-150° C., preferably 80-120° C., and more preferably 90-100° C. Specifically, the heat source may be a heatable air cylinder;

[0125] Finally, glue is applied circumferentially on both ends of the shrink tube, and the outer tube 32 is inserted into the shrink tube to achieve a fixed connection with the needle body 31 through the glue; alternatively, the outer tube 32 is sleeved on the outside of the needle body 31, and the relative positions of the two are kept reasonable and fixed, and then glue is injected circumferentially from both ends of the outer tube 32 into the cavity between the needle body 31 and the outer tube 32 to achieve a fixed connection.

[0126] Based on the improvements of the moving mechanism and the sampling needle 3 introduced above, the present invention improves the anti-liquid-throwing ability of the sampling needle 3 during the test liquid transportation process; and also reduces the requirements on the performance of the driving component during the reagent transportation process.

[0127] The present application also provides an analyzer having the anti-fluid rejection device described in the above embodiment. Specifically, the analyzer can be a chemiluminescence analyzer, a biochemical analyzer, a urine analyzer, a coagulation analyzer, etc.

[0128] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can easily think of various equivalent modifications or replacements within the technical scope disclosed by the present invention, and these modifications or replacements should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention shall be based on the protection scope of the claims.

Claims

1. An anti-flushing liquid sampling device, comprising a sampling needle, characterized in that: The sampling needle comprises a needle body, an outer tube and a fixing piece, wherein the outer tube is sleeved on the outside of one end of the needle body, and one end of the needle body is connected to the fixing piece; Wherein, the outer tube has a first extension section extending outwardly relative to the fixing member by a length of L, and the needle body has a second extension section extending outwardly relative to the fixing member by a length of M, and 0.2≤L / M≤0.6; The device also includes a moving mechanism, which includes a rotatable rocker arm; one end of the rocker arm is a rotation center, and the other end is provided with the sampling needle; Among them, the closer the position on the rocker arm is to the sampling needle, the smaller the unit mass is; or, within the length of a certain part or some parts of the rocker arm, the unit mass does not change with the change of the distance from the sampling needle, and the certain part or some parts of the rocker arm include: the area where the rocker arm is subjected to consistent force or the area between two points where there is a difference in the force change of the rocker arm.

2. The anti-flushing liquid sampling device according to claim 1, characterized in that: The farther the rocker arm is from the rotation center, the smaller the bending section moment is; Alternatively, within the length of a certain portion or certain portions of the rocker arm, the bending section moment does not change with the change of the distance from the sampling needle.

3. The anti-flushing liquid sampling device according to claim 2, characterized in that: The relationship between the length of the rocker arm and the moment of bending resistance along the length direction is: f(x)=a1x+b1, x∈[0, L1); f(x)=a2x+b2, x∈[L1, L2); f(x)=a3x+b3, x∈[L2, L3]; Among them, f(x) is the bending section moment at the corresponding position; a1, a2, a3, b1, b2, b3 are all coefficients; x, L1, L2 and L3 all represent the distance from the rotation center on the rocker arm.

4. The anti-flushing liquid sampling device according to claim 2, characterized in that: The relationship between the unit mass of the longitudinal section of the rocker arm along the length direction and the bending section moment at the corresponding position is: f(x)=a*e bx Where a and b are coefficients, x represents the unit mass of the longitudinal section, and f(x) is the bending section moment at the corresponding longitudinal section.

5. The anti-flushing liquid sampling device according to any one of claims 1 to 4, characterized in that: The moving mechanism also includes a floating connection component; the floating connection component is connected to one end of the rocker arm and is used to drive the rocker arm to rotate and move linearly; the floating connection component is floatingly connected to the rocker arm in the vertical direction to absorb the stress generated by the rocker arm during the vertical movement.

6. The anti-flushing liquid sampling device according to claim 5, characterized in that: The floating connection assembly includes: a base, a center spline, an adapter plate, a driving member and a guide member; the center spline passes through the top of the base and can move up and down in the base, the center spline passes through one end of the base and is connected to one end of the rocker arm, the center spline is located in the internal cavity of the base and is fixedly connected to the adapter plate; the driving member and the guide member are both arranged in the internal cavity of the base, the driving member is fixedly connected to the adapter plate and is used to drive the center spline to move up and down in the base; the guide member is floatingly connected to the adapter plate in the vertical direction.

7. The anti-flushing liquid sampling device according to claim 6, characterized in that: The guide member comprises a connecting plate, a connecting port is arranged in the adapter plate, the connecting plate is extended in the horizontal direction and inserted in the connecting port, and a movable gap is left between the connecting plate and the inside of the connecting port in the vertical direction.

8. The anti-flushing liquid sampling device according to any one of claims 1 to 4, characterized in that: The sampling end of the sampling needle adopts a variable diameter structure; or the surface of the needle body of the sampling needle is coated with a hydrophobic layer; or an insulating layer is arranged on the outer side of the needle body of the sampling needle.

9. An analyzer, characterized in that: The invention comprises the anti-flushing liquid sampling device according to any one of claims 1 to 8.

Images