Pharmaceutical composition containing ilex asprella, heat-clearing and inflammation-eliminating preparation and preparation method thereof

By using a compound flavoring agent of sucralose, steviol glycosides and citric acid in the Qingre Xiaoyan Ning preparation, the problem of the bitter taste of Jiujiecha was solved, improving the taste of the preparation and the medication compliance of pediatric patients.

CN118105418BActive Publication Date: 2025-12-05HINYE PHARM CO LTD
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Patent Information

Application Number
CN202410096919.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-01-24
Publication Date
2025-12-05
Estimated Expiration
2044-01-24

AI Technical Summary

Technical Problem

The bitter and astringent taste of the nine-section tea in the existing heat-clearing and anti-inflammatory preparations is extremely unpleasant, especially for children, and affects medication adherence.

Method used

Sucralose, steviol glycosides, and citric acid are used as compound flavoring agents to improve the taste through synergistic effects. The specific ratio is 100 parts of dried tea powder, 0.36 parts of sucralose, 1.1 parts of steviol glycosides, and 0.10 parts of citric acid.

Benefits of technology

The taste of the Qingre Xiaoyan Ning preparation has been significantly improved, eliminating any unpleasant odor and reducing bitterness and astringency, making it suitable for pediatric patients and improving medication adherence.

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Abstract

The application discloses a medicine composition containing Ilex hainanensis, a heat-clearing and inflammation-resolving preparation and a preparation method thereof, and the medicine composition containing Ilex hainanensis comprises the following raw material components in parts by weight: Ilex hainanensis dry extract powder 100 parts; sucralose 0.30-0.40 parts; stevioside 1.00-1.20 parts; citric acid 0.05-0.15 parts. The medicine composition containing Ilex hainanensis and the heat-clearing and inflammation-resolving preparation provided by the application use sucralose, stevioside and citric acid as a composite flavoring agent, the three components are mutually coordinated, the oral compliance of the preparation is successfully improved, the bitterness and astringency of the heat-clearing and inflammation-resolving preparation obtained after the composite flavoring agent is added according to the amount are well improved, there is no bad smell, and the overall taste is good.
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